Academic literature on the topic 'Cnaeus Marcius'

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Journal articles on the topic "Cnaeus Marcius"

1

Martell, Henry J., Avanthi Tayi Shah, Alex G. Lee, et al. "Abstract 54: Integrative analysis of whole-genome and RNA sequencing in high-risk pediatric malignancies." Cancer Research 82, no. 12_Supplement (2022): 54. http://dx.doi.org/10.1158/1538-7445.am2022-54.

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Abstract The use of sequencing-based assays for clinical management of pediatric cancer patients has become increasingly common. However, for many pediatric patients, gene panel based sequencing tests yield few actionable results. Given the complex genomic alterations present in many pediatric cancers, especially high-risk solid tumors, we hypothesized that an unbiased approach might reveal more actionable findings and lead to a more comprehensive understanding of these diseases. To accomplish this, we integrated whole-genome sequencing (WGS) with RNAseq in the analysis of a pediatric oncology
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2

Martell, Henry J., Avanthi T. Shah, Alex G. Lee, et al. "Abstract 1509: Longitudinal profiling of high-risk pediatric malignancies using a multiomics approach." Cancer Research 83, no. 7_Supplement (2023): 1509. http://dx.doi.org/10.1158/1538-7445.am2023-1509.

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Abstract For many pediatric cancer patients, commonly used gene-panel sequencing tests yield few actionable results, partly due to the complex genomic alterations present. We hypothesized that an unbiased approach, combining whole-genome (WGS) and RNA sequencing (RNAseq), could overcome this and lead to a more comprehensive understanding of these diseases. While prior studies have evaluated WGS and RNAseq in pediatric cancers, few focused primarily on metastatic or relapsed disease. We also placed special focus on longitudinal profiling of patients, including with additional deep sequencing, t
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3

Prip, Frederik, Philippe Lamy, Iver Nordentoft, et al. "Abstract 6075: Comprehensive genomic characterization of early-stage bladder cancer from 438 patients by whole genome- and exome sequencing." Cancer Research 83, no. 7_Supplement (2023): 6075. http://dx.doi.org/10.1158/1538-7445.am2023-6075.

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Abstract Background: The genomic landscape of cancer is complex and includes mutations and copy number alterations (CNAs) that affect several cancer related pathways and drive tumor evolution. Non-muscle-invasive bladder cancers (NMIBC) are largely orphan for integrative genomic studies. Large studies are needed to delineate the genomic complexity and heterogeneity of NMIBC. Methods: A total of 438 patients with NMIBC were analyzed, 296 of which were part of the UROMOL cohort (PMID: 27321955). The median follow-up was 5 years. The progression rate was 13% (n= 56). Whole exome sequencing (WES)
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4

Macaulay, Charles W., Marcus R. Breese, and E. Alejandro Sweet-Cordero. "Abstract B011: Dynamics of predicted tumor neoepitope burden in a pan-cancer solid tumor pediatric cohort." Cancer Immunology Research 11, no. 12_Supplement (2023): B011. http://dx.doi.org/10.1158/2326-6074.tumimm23-b011.

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Abstract Human leukocyte antigen (HLA) binding of tumor neoepitopes confers clinical value in certain adult malignancies. However, the prevalence of tumors that result in HLA binding of neoepitopes in pediatric malignancies is not as well-characterized. We set out to establish the feasibility of predicting neoepitope burden and the prevalence of predicted neoepitope across a previously established cohort of pediatric oncology patients. Additionally, because this analysis requires knowledge of each patient’s HLA haplotype for predicting binding of tumor peptides, we also set out to develop a no
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Books on the topic "Cnaeus Marcius"

1

1952-, Wofford Susanne Lindgren, ed. Shakespeare's late tragedies: A collection of critical essays. Prentice Hall, 1996.

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2

Shakespeare, William. Coriolanus. Standard Ebooks, 2022.

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