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1

Romanato, Luiz Sergio. ""Armazenagem de combustível nuclear queimado"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-15052006-220434/.

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Quando um país se torna auto-suficiente em uma parte do ciclo nuclear, quanto à produção de combustível que será usado em suas centrais nucleares para a geração de energia, precisa voltar sua atenção para a melhor forma de armazenar este combustível após a sua utilização. A armazenagem do combustível nuclear queimado é uma prática necessária e utilizada nos dias atuais em todo o mundo como temporária, tanto por países que não têm definido o plano de destinação final, isto é, o repositório definitivo, como também por aqueles que já o possuem. Existem dois aspectos principais que envolvem os com
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Coq, Guilhelm. "Utilisation d'approches probabilistes basées sur les critères entropiques pour la recherche d'information sur supports multimédia." Poitiers, 2008. http://theses.edel.univ-poitiers.fr/theses/2008/Coq-Guilhelm/2008-Coq-Guilhelm-These.pdf.

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Les problèmes de sélection de modèles se posent couramment dans un grand nombre de domaines applicatifs tels que la compression de données ou le traitement du signal et de l’image. Un des outils les plus utilisés pour résoudre ces problèmes se présente sous la forme d’une quantité réelle à minimiser appelée critère d’information ou critère entropique pénalisé. La principale motivation de ce travail de thèse est de justifier l’utilisation d’un tel critère face à un problème de sélection de modèles typiquement issu d’un contexte de traitement du signal. La justification attendue se doit, elle, d
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Claesson, Göran, and Jonas Silverborn. "Multifunktionell CNC-maskin." Thesis, Högskolan i Halmstad, Sektionen för Informationsvetenskap, Data– och Elektroteknik (IDE), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-24576.

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Lundstedt, Anders. "Realizability in Coq." Thesis, KTH, Matematik (Avd.), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-174109.

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This thesis describes a Coq formalization of realizability interpretations of arithmetic. The realizability interpretations are based on partial combinatory algebras—to each partial combinatory algebra there is an associated realizability interpretation. I construct two partial combinatory algebras. One of these gives a realizability interpretation equivalent to Kleene’s original one, without involving the usual recursion-theoretic machinery.<br>Den här uppsatsen beskriver en Coq-formalisering av realiserbarhetstolkningar av aritmetik. Realiserbarhetstolkningarna baseras på partiella kombinato
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Doody, Aaron L. (Aaron Lee). "CNC router modernization." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/40405.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.<br>Includes bibliographical references.<br>A large-format CNC router has been stored in the Pappalardo Laboratory wood shop for several years in an unusable state. A need assessment determined that it would be cost effective to bring the router online for use in the mechanical engineering curriculum. The router was cleaned and inspected; it was determined that the router was in sound mechanical condition. The stepper motors, control system, and power supply were also functional, but the CNC interface s
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Krejčí, Jan. "CNC řízení frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2021. http://www.nusl.cz/ntk/nusl-442459.

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This diploma thesis deals with rebuild of manual drill-mill machine BF20L into CNC mill machine, 3D model of that and eventual control using PLC. All axes are powered by stepper motors, with encoders, connected to control cards and industrial computer from company Beckhoff. For this control is made full switchboard, supplemented by electrical wiring diagram. Program control along with visualization is made in software TwinCAT 3. Drill-mill machine can be controlled manually or automatically by program.
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Claret, Guillaume. "Program in Coq." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCC068/document.

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Dans cette thèse, nous cherchons à développer de nouvelles techniques pour écrire plus simplement des programmes formellement vérifiés. Nous procédons en étudiant l'utilisation de Coq en tant que langage de programmation dans différents environnements. Coq étant un langage purement fonctionnel, nous nous concentrons surtout sur la représentation et la spécification d'effets impurs, tel que les exceptions, les références mutables, les entrées-sorties et la concurrence.Nous travaillons premièrement sur deux projets préliminaires qui nous aident à comprendre les défis existants dans la programmat
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PERSSON, LINUS, and NATALIJA ZIVANOVIC. "Picasso : CNC plotter." Thesis, KTH, Mekatronik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-233002.

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In today’s society, CNC machines are used for various purposes. In this project, a CNC plotter is created to analyze how the performance of the plotter differs when using two different motors: a DC motor controlled by a potentiometer in the horizontal direction and a stepper motor in the vertical direction. A CNC plotter is built and used to do tests in order to answer the research question. The results show that a DC motor with a potentiometer is more precise than a stepper motor and the mean value of the relative errors in the vertical direction is always higher. The values differ with 1 per
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9

Kovář, Pavel. "Model CNC frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219700.

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The master's thesis deals with the basic parts and principles of CNC machines with a focus on a CNC milling machine. There are also comparisons of several CNC machines sold. Furthermore, the project deals with the description of the manipulator, which is situated in laboratory E-132 in area Kolejní 4, Brno. The work also includes a description of the device, which is located in the manipulator model. We can find there a description of the program generating G-code from the image that you create in the editor. The next section describes possible modifications of the manipulator for its reconstr
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Moštěk, Jiří. "Malý CNC stroj." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2014. http://www.nusl.cz/ntk/nusl-220350.

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This diploma thesis deals with the design and construction of a three-axis CNC machine primarily designed for PCB drilling and production of front panels for various electronic devices. All three axes are driven by stepper motors NEMA 23 which are connected to stepper motor drivers L6470. Processor STM32F407 is used to control the whole machine. The wiring is completed by a LCD display with touchscreen which is used to communicate with user. Data for drilling can be entering manually or via USB inerface. Part of this thesis is the selection of a suitable construction and components, assembling
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Vondrák, Jan. "Technologie CNC frézování." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-228933.

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Common possibility analysis on milling machine, analysis possibility for programming in workshop oriented milling in system Sinumerik 840D ShopMill. Project alternative manufacturing technology including creation NC programme and technical economic valuation for part of Suspension globular screw in axis X.
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Drlík, Michal. "Souřadnicová CNC vrtačka." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229482.

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This thesis deals with designing and realization of a CNC drill. The body of the thesis is divided into three parts: Firstly, a design of a mechanical construction, secondly, an electronic scheme with its realization using industrial components and lastly, a design of a data export from an application for DPS EAGLE designing to G-KOD formate. The whole process should make drilling of plates with DPS or eventually the whole plate manufacturing more efficient and the quality and accurancy of a whole work should increase.
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Žák, Petr. "Konstrukce CNC frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-231996.

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The diploma thesis includes design of vertical CNC milling machine. It also includes research in the field of CNC milling machines on the world market, which is carried out to select the appropriate machine parameters and the structural configuration of the machine. Another part of the thesis deals with the selection of suitable components, design calculations, manufacturing drawings and the 3D model showing the final design solution of proposed machine.
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Pospíšil, Jiří. "Hobby CNC frézka." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-232104.

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This diploma thesis serves as experimental proof of real world capabilities of computer designed hobby CNC milling machine with its parts printed on a 3D printer. First half is a brief introduction of CNC technologies to non-professional audience. Second part together with 3D model works as manual to build your own machine. Priority was to keep costs to minimum with decent accuracy still in mind.
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Kalina, Vladimír. "Malá CNC frézka." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-319489.

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The content of this diploma thesis is the design and construction of small vertical CNC milling machines. In the thesis are listed and machines that appear in today's production on the market. The components are designed for tools, for ball screw, linear guide. Parts are attached to the 3D models with vertical machine and drawings of the proposed machinery.
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Beránek, Jakub. "Bezpečnost CNC brusek." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-382265.

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This thesis deals with safety of the CNC grinding machines. The first part of this thesis is focusing on legislative requirements of EU and Czech Republic, which concern with topic of this thesis. The second part of the thesis is focusing on the safety of the chosen grinding machine. The main parts of the machine which are important for safety are described and then the checklists for verification of the safety requirements are made.
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Hanulík, René. "Řízení CNC pískovačky." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2020. http://www.nusl.cz/ntk/nusl-413120.

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The diploma thesis clarifies the issue of creating inscriptions on stone slabs. It describes some types of sensors, actuators, their physical principles and possibilities of their use. The work mentions the limitations and specifics of sandblasting, design solutions and implementation of equipment for patternless sandblasting.The functionality of the device is demonstrated and verified on illustrative examples.
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Chaňo, Patrik. "Hobby CNC frézka." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-416606.

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This diploma thesis serves as a design and implementation of a hobby CNC milling machine, for the modeling community. The work is conceived as an overview of the most common machining technologies. The following is an introduction to the construction of CNC milling machines and an introduction to the basic components used. Furthermore, the actual design proposals and a description of the implementation of two of them are presented. When designing the machine, emphasis was placed on the lowest possible price and availability of individual components.
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Persson, Linus, and Natalija Zivanovic. "Picasso : CNC plotter." Thesis, KTH, Maskinkonstruktion (Inst.), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-230244.

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In today’s society, CNC machines are used for various purposes.In this project, a CNC plotter is created to analyzehow the performance of the plotter differs when using twodifferent motors: a DC motor controlled by a potentiometerin the horizontal direction and a stepper motor in thevertical direction. A CNC plotter is built and used to dotests in order to answer the research question. The resultsshow that a DC motor with a potentiometer is more precisethan a stepper motor and the mean value of the relative errorsin the vertical direction is always higher. The valuesdiffer with 1 percentage po
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Lynch, Nick. "The C1q receptors." Thesis, University of Leicester, 1997. http://hdl.handle.net/2381/29753.

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Calreticulin is widely, abundantly and constituatively expressed; it has no transmembrane domain and it is found mainly in the endoplasmic reticulum. These features are characteristic of a house-keeping protein, not of a cell surface receptor. Moreover, the pI of the calreticulin is very low, while that of C1q is very high, suggesting that its retention on C1q affinity columns might be the result of non-specific interactions. This study sought to identify a membrane-targeted isoform of calreticulin that might represent a functional C1q receptor. Northern blot analyses, genomic Southern blots a
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Sers, Rickard, and Victor Wiberg. "Konstruktion av CNC-Router." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-23611.

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AASS (Applied Autonomous Sensor Systems, Centrum för Tillämpade Autonoma Sensorsystem) arbetar med forskning inom autonoma system. Deras stora användningsområden är utveckling av automatiska system till fordonsindustrin samt system till äldrevården. AASS, har ett önskemål om en enklare modell av en CNC fräs för enklare fräsning till bland annat prototyptillverkning. Fokus ska ligga på kostnaden då precisionen inte är av största intresse. Uppdraget innebär att ta fram en konstruktion av en cnc- router med tre axlar med ett arbetsrum på 600x450x150mm. Maskinen ska kunna skära i mjuka material so
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Carpani, Valerio. "CNN-based video analytics." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018.

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The content of this thesis illustrates the six months work done during my internship at TKH Security Solutions - Siqura B.V. in Gouda, Netherlands. The aim of this thesis is to investigate on convolutional neural networks possible usage, from two different point of view: first we propose a novel algorithm for person re-identification, second we propose a deployment chain, for bringing research concepts to product ready solutions. In existing works, the person re-identification task is assumed to be independent of the person detection task. In this thesis instead, we consider the two ta
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Malhotra, Rajneesh. "Human leukocyte C1q receptor." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.481094.

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Kotter, Mark Reinhard. "Macrophages and CNS remyelination." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614264.

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Penderis, Jacques. "Neuregulins and CNS remyelination." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620066.

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Mitáš, Daniel. "Ovládací rozhraní CNC frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219821.

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This project deals with portal-type CNC milling machine design and construction. CNC milling machine should be able to machining light metals and alloys. This document contains description of mechanical components selection, machine frame design and building, design and construction of USB motion control unit and also contains control software description and user manual.
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Podloucký, Milan. "Konstrukce malého CNC soustruhu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230138.

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The aim of this master thesis is construction a small CNC lathe ideal for small series of mostly minor workpieces or for learning needs. In the first part of the work is carried out general literature search containing turning technology, tools for turning and the allocation of turning machines. There is also retrieval of small lathes located not only in our market. Based on research are selected technical parameters of the machine and carried out construction calculations. Also included is a 3D model of the entire assembly and assembly drawings of machine nodes.
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Jagoš, Roman. "Konstrukce malé CNC frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230234.

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This master´s thesis deals with design of small CNC milling machines and comparing CNC tabletop milling machines in the world market. It is also done design of small CNC milling machine through the use of contemporary and modern trends, used in design of machine tools.
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Sobotka, Ondřej. "Návrh CNC řídicího systému." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2014. http://www.nusl.cz/ntk/nusl-231279.

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The thesis describesthedesign of a controlsystemfor CNC applicationswhich do not requiresynchronizedmotionofseveral axis atonce. Thegoaliscompatibilitywith G-codethatallowsyou to controlthedevicewith a Cartesiancoordinatesystem. Withthe use ofthenormal PC to run thesystem and communicate via serial line.
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Cherepanov, Maksym. "Ruční programovaní CNC strojů." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-317201.

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Kučera, David. "CNC obrábění rotační součásti." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-417437.

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The diploma thesis concerns CNC machining of rotary part. The first part briefly introduces options of multipurpose CNC machines and robotized workplaces. The main body of the thesis analyses two production departments; one of them operated by a robotic manipulator. The conclusion summarises the accomplished results of the thesis.
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Buš, Martin. "Návrh hobby CNC frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-417754.

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This master thesis is focused on design of CNC hobby milling machine.In the first part of master thesis there are brief information about construction of CNC milling machines with varios types of milling machines available on market. After that, is made a selection of suitable machine componets for selected parameters. Futhermore, the masters thesis include a solutions of the component on all axes CNC milling machines.
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McAdam, R. A. "Cloning and characterisation of human C1q genes in normals and C1q deficient patients." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376928.

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Berjaud, Clémentine. "« Cinq sur cinq, mi comandante ! » : contribution à l’étude des réceptions des discours politiques télévisés." Thesis, Paris 1, 2014. http://buadistant.univ-angers.fr/login?url=https://www.dalloz-bibliotheque.fr/pvurl.php?r=http%3A%2F%2Fdallozbndpro-pvgpsla.dalloz-bibliotheque.fr%2Ffr%2Fpvpage2.asp%3Fpuc%3D5442%26nu%3D159%26selfsize%3D1.

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Cette thèse porte sur les réceptions des discours politiques télévisés par les citoyens ordinaires. En prenant pour terrain le Venezuela d’Hugo Chavez, ce travail propose un cadre d’analyse de la réception des discours politiques, focalisé sur les récepteurs, leurs pratiques concrètes, et attentif aux ancrages sociaux de ces processus. La réception se compose de différentes étapes, entre exposition, attention, interprétations et réceptions différées. Pour chacune de ces étapes, les rapports au politique des citoyens entrent en jeu, guidant et conditionnant leurs réceptions. Cette enquête multi
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Bhandavat, Romil. "Molecular precursor derived SiBCN/CNT and SiOC/CNT composite nanowires for energy based applications." Diss., Kansas State University, 2013. http://hdl.handle.net/2097/15347.

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Doctor of Philosophy<br>Department of Mechanical and Nuclear Engineering<br>Gurpreet Singh<br>Molecular precursor derived ceramics (also known as polymer-derived ceramics or PDCs) are high temperature glasses that have been studied for applications involving operation at elevated temperatures. Prepared from controlled thermal degradation of liquid-phase organosilicon precursors, these ceramics offer remarkable engineering properties such as resistance to crystallization up to 1400 °C, semiconductor behavior at high temperatures and intense photoluminescence. These properties are a direct resu
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Lara, Teodoro. "Controllability and applications of CNN." Diss., Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/28921.

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Birzniece, Vita. "Neuroactive steroids and rat CNS." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-296.

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Mitchell, Daniel Anthony. "C1q deficiency and murine lupus." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342252.

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Bourdon, Pierre. "Le quinquennat, cinq ans après /." Paris : l'Harmattan, 2008. http://catalogue.bnf.fr/ark:/12148/cb41220316k.

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Rogers, Madolyn Bowman. "Control of CNS neuronal survival /." May be available electronically:, 2007. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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Fancy, Stephen Philip James. "Transcriptional control of CNS remyelination." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613013.

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Rautava, J. P. (Jori-Pekka). "CNC-jyrsimen tärinän mittaus värinäsensorilla." Bachelor's thesis, University of Oulu, 2017. http://urn.fi/URN:NBN:fi:oulu-201710072962.

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Tässä työssä tehdään ensin kirjallisuuskatsaus LTE-tekniikan perusteisiin sekä 5G-tekniikan käyttöön ja mahdollisuuksiin IoT-sovellutuksissa. Teoriaosuudessa tarkastellaan mistä osista LTE-tekniikka koostuu ja mitkä ovat keskeisiä asioita LTE-tekniikan mahdollistamassa suuremmassa datan siirtonopeudessa verrattuna 3G tekniikkaan. 5G-tekniikkaan liittyen esitellään 5G:n perusideat ja miksi se mahdollistaa entistä suuremmat datan siirtonopeudet ja pienemmät latenssit kuin 4G-tekniikka. Tämän työn lopussa on esitelty tekemäni IoT-sovellus, jossa CNC-jyrsimestä voidaan mitata tärinäarvoja käyttäen
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Jakubiec, Line. "Vérification de circuits dans Coq." Aix-Marseille 1, 1999. http://www.theses.fr/1999AIX11030.

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La verification formelle de circuits integres garantit de facon rigoureuse leur fiabilite. Pour ce faire, les assistants de preuve sont de plus en plus utilises. Le systeme coq, base sur le calcul des constructions inductives avec types co-inductifs, presente des particularites interessantes et originales. Nous etudions ce que ce systeme peut apporter dans le domaine de la specification et de la verification de circuits. Apres avoir montre l'interet des types dependants pour donner des specifications de circuits precises et donc fiables, nous utilisons le mecanisme d'extraction coq pour synthe
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Sarda, Christine. "Chronotoxicité de cinq antiépileptiques majeurs." Bordeaux 2, 1996. http://www.theses.fr/1996BOR2P014.

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Matoušek, Vojtěch. "Návrh a řízení CNC stroje." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2011. http://www.nusl.cz/ntk/nusl-218945.

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My task was to build a smaller structure triaxial CNC milling. I designed electronics for motion control. The main part is the implementation of the control unit, which will provide control of the machine. The work includes the complete design, PCB design and program description for the uP ARM. The unit can work independently as well as hardware interpolator connected to the PC.
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Vlček, Michal. "Integrace měření do CNC obrábění." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-229070.

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This master thesis deals with integration of measuring into process of machining. The object of this work is making summary of using measuring probes, description of the probes working principles and their division by construction and usage. The practical part of this work deals with creation of measuring cycles in softwaru Productivity+ and their implementation to machining cycles in MCV 1210. In the last part, two testing workpieces were created and the economic evaluation of introduction of the probes into machining process was performed.
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47

Michele, Jiří. "Konstrukce malé vertikální CNC frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230492.

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This diploma thesis designs a small vertical CNC milling machine. The thesis includes selection of suitable structural design of the machine based on market analysis and requirements. The listed components, constructional calculations and 3D model are chosen in order to minimize the costs.
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48

Kubiš, Richard. "Analýza minutové sazby CNC strojů." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-231016.

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This master’s thesis is focused on analysis of the minute cost rate for CNC machines. It describes cost inputs and a way of including them in the minute cost rate. Further describes creating of mathematical model, minute rates for entire CNC machine and possibilities of using of the minute rate for optimalisation. It points out that no general calculation method is existing and that there are problems with creating certain minute rate and need of individal approach.
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49

Ludva, Jan. "Konstrukční návrh portálové CNC frézky." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-241719.

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This master’s thesis deals with a design of a portal CNC milling machine. The thesis contains a description of milling machine’s single types, analysis of Czech and foreign market and analysis of basic milling machine’s groups. The work includes calculating of cutting forces and moments of a chosen tool, choice of spindle and design of axe’s drive systems. The thesis also includes 3D model of the chosen variant, it’s by a method of final elements and finally drawing documentation.
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50

Lacinová, Michaela. "Detekce CNV v bakteriálních genomech." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2019. http://www.nusl.cz/ntk/nusl-400996.

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This master thesis deals with analysis of structural variation of genome and with methods of its sequencing across all generations. Subsequently it contains a description of copy number variation and methods of its detection. The experimental part focuses on algorithm proposal for CNV detection according analysis and testing of uneven coverage in genome, variable representation of GC content and distance of sequence reads. Finally, the algorithm for detecting copy number variation is tested on genomic data of bacteria Klebsiella pneumoniae.
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