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Journal articles on the topic 'CNS condition'

Author: Grafiati

Published: 10 December 2022

Last updated: 19 July 2025

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1

Silver, Jerry. "CNS Regeneration: Only on One Condition." Current Biology 19, no. 11 (2009): R444—R446. http://dx.doi.org/10.1016/j.cub.2009.04.026.

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Han, Guansheng, Fei Xiong, Yu Zhou, Leibo Song, and Xingkai Wang. "Research Progress on Shear Characteristics of Rock Joints under Constant Normal Stiffness Boundary Conditions." Shock and Vibration 2021 (September 1, 2021): 1–6. http://dx.doi.org/10.1155/2021/9670151.

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The constant normal stiffness (CNS) boundary condition is more representative for the underground engineering, in which the shear-induced dilation is restricted by surrounding rocks, resulting in an increase in the normal stress. Therefore, the use of CNS boundary conditions in the research of shear-slip failure of underground rock engineering is more in line with the actual situation. Taking the instability and failure of surrounding rock in underground engineering as the background, the present study introduces the engineering background of CNS boundary conditions and the research progress o

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Cao, Yangbing, Yang Wu, Xiangxiang Zhang, Zhi Liu, Weiguo Gong, and Zhenping Huang. "Experimental Study on the Influence of Hydromechanical Boundary Conditions on Shear-Flow Coupling Characteristics of Granite Joints." Geofluids 2022 (August 22, 2022): 1–17. http://dx.doi.org/10.1155/2022/4030000.

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The instability of jointed rock mass is usually the shear process of the rock mass along discontinuities under the influence of groundwater flow. By conducting laboratory tests and numerical experiments on the shear-flow coupling of rock joints under constant normal stiffness (CNS) and constant normal stress (CNL) boundary conditions, the influence of normal boundary conditions and seepage pressure on the shear mechanical and flow characteristics of joints were investigated. The test results were as follows: The joint shear stiffness, peak, and residual shear strength under the CNS boundary co

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Webber, Parker, Brianna C. Landis, and Amanda E. Brooks. "Recontextualizing Neuromyelitis Optica as a Systemic Condition: A Perspective." Journal of Clinical & Translational Ophthalmology 1, no. 2 (2023): 61–71. http://dx.doi.org/10.3390/jcto1020008.

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Neuromyelitis optica spectrum disorder (NMOSD), a demyelinating CNS disorder in which inflammatory cells infiltrate the spinal cord and optic nerve, has been identified as an AQP4-IgG-positive disease. Some of its most common clinical characteristics are optic neuritis, acute myelitis, area postrema syndrome, and brainstem syndrome. However, the relationship between aquaporin-4 (AQP4) and NMOSD appears to be involved in pathologies outside of the CNS due to the fact that autoimmune, muscular, and paraneoplastic syndromes are more common in patients with NMOSD. This perspective presents an anal

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Balasubramaniam, Srikant, Monali Mahadev Patil, Nakul Rathore, and Hemant M. Jawale. "CNS Neuroblastoma FOXR2 Mimicking a Benign Condition: A Diagnostic Conundrum." Journal of Pediatric Neurosciences 19, no. 3 (2024): 107–10. https://doi.org/10.4103/jpn.jpn_128_23.

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Abstract Diagnostic dilemmas are common in central nervous system (CNS) lesions. It is important to have a proper neuropathological diagnosis, as the treatment of benign conditions is different from malignant tumors. Our case report is an example of a diagnostic dilemma, which commonly accompanies rare malignancies lacking unique characteristics and literature support. An 11-year-old child was diagnosed with intracranial tuberculoma with meningoencephalitis and started on antituberculous drugs. After 6 months, the patient presented with a paroxysmal event and raised intracranial pressure. A gr

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Sanei Taheri, Morteza, Mohammad Ali Karimi, Hamidreza Haghighatkhah, Ramin Pourghorban, Mohammad Samadian, and Hosein Delavar Kasmaei. "Central Nervous System Tuberculosis: An Imaging-Focused Review of a Reemerging Disease." Radiology Research and Practice 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/202806.

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Central nervous system (CNS) tuberculosis is a potentially life threatening condition which is curable if the correct diagnosis is made in the early stages. Its clinical and radiologic manifestations may mimic other infectious and noninfectious neurological conditions. Hence, familiarity with the imaging presentations of various forms of CNS tuberculosis is essential in timely diagnosis, and thereby reducing the morbidity and mortality of this disease. In this review, we describe the imaging characteristics of the different forms of CNS tuberculosis, including meningitis, tuberculoma, miliary

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Kanaev, A. K., E. V. Oparin, and E. V. Oparina. "Entropic model of network dynamics of clocking network synchronization." Journal of Physics: Conference Series 2131, no. 4 (2021): 042089. http://dx.doi.org/10.1088/1742-6596/2131/4/042089.

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Abstract The main task of the clocking network synchronization (CNS) network subsystem is the formation, transmission, distribution and delivery of synchronization signals to the telecommunication system (TCS) digital equipment for the purpose of its coordinated interaction. Indicators of the telecommunication services quality are inextricably linked with the indicators of the CNS network functioning quality, in this regard, the process of monitoring and managing the CNS network comes to the fore for the purpose of prompt detection of failures and their subsequent elimination. The article prov

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Gupta, Lipika, and Archit Gupta. "Central nervous system manifestations in HIV: magnetic resonance imaging pictorial review." International Journal of Research in Medical Sciences 11, no. 8 (2023): 3115–20. http://dx.doi.org/10.18203/2320-6012.ijrms20232460.

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Human immunodeficiency virus (HIV) is a member of the Retroviridae (retrovirus) family. It is associated with immunodeficiency, neurological diseases and neoplasms. With the use of antiretroviral therapy (ART), the prognosis of people who are infected with HIV has improved, and the incidence of HIV-related central nervous system (CNS) diseases has markedly decreased. In spite of that the mortality from HIV-related CNS diseases remains significant. Magnetic resonance imaging (MRI) has improved the perspective for people with HIV with the help of early diagnosis and prompt treatment. There are v

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Srithanasuwan, Anyaphat, Montira Intanon, Wasana Chaisri, and Witaya Suriyasathaporn. "In Vitro Bacterial Competition of Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli against Coagulase-Negative Staphylococci from Bovine Mastitis Milk." Antibiotics 12, no. 3 (2023): 600. http://dx.doi.org/10.3390/antibiotics12030600.

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Intramammary infection (IMI) from the environment and infected quarters can cause co-infection. The objective of this study was to determine the ability of coagulase-negative staphylococci (CNS) to survive in the same environment as Staphylococcus aureus, Streptococcus agalactiae, and Escherichia coli as major pathogens. In total, 15 and 242 CNS strains were used in Experiment I and Experiment II, respectively. Both experiments were separated into three conditions: culture with CNS 24 h before (PRIOR), after (AFTER), and at the same time (EQUAL). The lack of a clear zone, regardless of size, w

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GUPTA, MOHIT, RAVI SHEKHAR, and JAGDISH K. SAHU. "ROLE OF DRUG DISCOVERY IN CENTRAL NERVOUS SYSTEM DISORDERS: AN OVERVIEW." Current Research in Pharmaceutical Sciences 11, no. 3 (2021): 86–90. http://dx.doi.org/10.24092/crps.2021.110302.

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Central nervous system (CNS) stimulants are drugs, which produce a response that could be used to alleviate a particular medical condition. These are the agents, which speed up to treat conditions characterized by lack of adrenergic stimulation, including narcolepsy and neonatal apnea. The majority of CNS stimulants is chemically similar to the neurohormone norepinephrine and simulates the traditional "fight or flight" syndrome associated with sympathetic nervous system arousal. A small figure of added members of the CNS stimulant class do not fall into definite chemical groups. The review on

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11

Behl, Ajay, Lorie Ellis, Dominic Pilon, Patrick Lefebvre, and Nancy Ann Dawson. "Observation of CNS events in real-world use of enzalutamide (ENZ) and bicalutamide (BIC)." Journal of Clinical Oncology 34, no. 2_suppl (2016): 235. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.235.

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235 Background: TERRAIN, a randomized, double-blind, multi-center, phase II trial compared efficacy and safety of ENZ to BIC in men with mCRPC. Although ENZ and BIC fall within the same drug classification, rates of seizure and other central nervous system (CNS) events, observed in non-clinical trial populations have not been explored. The objective of this study was to compare rates of real world CNS events in patients treated with ENZ or BIC. Methods: Retrospective claims from Truven Health MarketScan database were used to identify patients with a PC diagnosis; ≥1 claim for ENZ or BIC (index

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Weiner, Debra K., Angela Gentili, Katherine Coffey-Vega, Natalia Morone, Michelle Rossi, and Subashan Perera. "Biopsychosocial Profiles and Functional Correlates in Older Adults with Chronic Low Back Pain: A Preliminary Study." Pain Medicine 20, no. 7 (2018): 1300–1310. http://dx.doi.org/10.1093/pm/pny065.

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Abstract Objective To describe key peripheral and central nervous system (CNS) conditions in a group of older adults with chronic low back pain (CLBP) and their association with pain severity and self-reported and performance-based physical function. Design Cross-sectional. Setting Outpatient VA clinics. Subjects Forty-seven community-dwelling veterans with CLBP (age 68.0 ± 6.5 years, range = 60–88 years, 12.8% female, 66% white) participated. Methods Data were collected on peripheral pain generators—body mass index, American College of Rheumatology hip osteoarthritis criteria, neurogenic clau

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Wang, Xiangyu, Ruofan Wang, and Zizheng Zhang. "Numerical Analysis Method of Shear Properties of Infilled Joints under Constant Normal Stiffness Condition." Advances in Civil Engineering 2018 (August 1, 2018): 1–13. http://dx.doi.org/10.1155/2018/1642146.

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The direct shear test is implemented in this paper for infilled joints under constant normal stiffness (CNS) condition with the finite difference software FLAC3D. The CNS condition was performed based on a servoprogram developed by FISH language. The effects of initial normal stress, undulating angle, and infilled ratio on the shear failure mode of infilled joints under CNS are revealed based on numerical simulation. It is found that the shear strength of infilled joints will grow along with the increase of the undulating angle and the decrease of the infilled ratio. The numerical analysis met

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14

Bakirtzis, Christos, Maria Lima, Sotiria Stavropoulou De Lorenzo, et al. "Secondary Central Nervous System Demyelinating Disorders in the Elderly: A Narrative Review." Healthcare 11, no. 15 (2023): 2126. http://dx.doi.org/10.3390/healthcare11152126.

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Secondary demyelinating diseases comprise a wide spectrum group of pathological conditions and may either be attributed to a disorder primarily affecting the neurons or axons, followed by demyelination, or to an underlying condition leading to secondary damage of the myelin sheath. In the elderly, primary demyelinating diseases of the central nervous system (CNS), such as multiple sclerosis, are relatively uncommon. However, secondary causes of CNS demyelination may often occur and in this case, extensive diagnostic workup is usually needed. Infectious, postinfectious, or postvaccinal demyelin

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Luk’yanova, I. S., I. Yu Gordienko, G. F. Medvedenko, G. O. Grebinichenko, and B. A. Tarasyuk. "Pathology of provisional organs, complications of pregnancy and labor, and the condition of newborn with congenital defects of the urinary and nervous systems." UKRAINIAN JOURNAL OF PERINATOLOGY AND PEDIATRICS, no. 3(91) (September 30, 2022): 15–21. http://dx.doi.org/10.15574/pp.2022.91.15.

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Congenital malformations (CM) in fetuses and neonates belong to main causes of perinatal morbidity and mortality. Provision organs malformation and malfunction in such cohorts is less studied. The purpose - to analyze the course of pregnancy, the data of ultrasound imaging of provisional organs in the presence of CM of central nervous system (CNS) and/or of nephro-urinary system (NUS) in the fetus and newborn. Materials and methods. The results of prenatal and postnatal ultrasound, anamnestic and general clinical data of a sample of cases with prenatally diagnosed CM of CNS and/or NUS for the

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Busechian, Sara, Luca Turini, Micaela Sgorbini, et al. "Are Horse Owners Able to Estimate Their Animals’ Body Condition Score and Cresty Neck Score?" Veterinary Sciences 9, no. 10 (2022): 544. http://dx.doi.org/10.3390/vetsci9100544.

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Obesity and overconditioning are becoming more prevalent in horses, and are influencing the animal’s health, activity, and reproductive efficiency. Body condition score (BCS) and cresty neck score (CNS) have been correlated with the development of various diseases. Many of the papers in the literature evaluate the prevalence of obesity and overconditioning in horse populations considering BCS given by owners. The aim of this study was to evaluate the validity of the owners’ estimation of the degree of equine obesity or overconditioning by comparing BCS and CNS provided by each owner and a boar

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Sánchez Mainar, María, Stefan Weckx, and Frédéric Leroy. "Coagulase-Negative Staphylococci Favor Conversion of Arginine into Ornithine despite a Widespread Genetic Potential for Nitric Oxide Synthase Activity." Applied and Environmental Microbiology 80, no. 24 (2014): 7741–51. http://dx.doi.org/10.1128/aem.02298-14.

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ABSTRACTWithin ecosystems that are poor in carbohydrates, alternative substrates such as arginine may be of importance to coagulase-negative staphylococci (CNS). However, the versatility of arginine conversion in CNS remains largely uncharted. Therefore, a set of 86 strains belonging to 17 CNS species was screened for arginine deiminase (ADI), arginase, and nitric oxide synthase (NOS) activities, in view of their ecological relevance. In fermented meats, for instance, ADI could improve bacterial competitiveness, whereas NOS may serve as an alternative nitrosomyoglobin generator to nitrate and

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18

Hall, Leanne M., Sandra Brauer, Fay Horak, and Paul W. Hodges. "Adaptive Changes in Anticipatory Postural Adjustments With Novel and Familiar Postural Supports." Journal of Neurophysiology 103, no. 2 (2010): 968–76. http://dx.doi.org/10.1152/jn.00479.2009.

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Anticipatory postural adjustments (APAs) serve to stabilize posture prior to initiation of voluntary movement. This study examined the effects of changes in postural support on APAs using novel and familiar support paradigms. We also investigated whether postural strategies were refined with practice and how the CNS responded when multiple supports were available. Twelve healthy subjects stood on dual force platforms and performed 20 randomized left and right rapid leg-lift tasks in response to a visual cue under four conditions: unsupported, bilateral handgrip, bite plate, and a combined hand

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Sano, Renata, Alessandra Tessitore, Angela Ingrassia, and Alessandra d'Azzo. "Chemokine-induced recruitment of genetically modified bone marrow cells into the CNS of GM1-gangliosidosis mice corrects neuronal pathology." Blood 106, no. 7 (2005): 2259–68. http://dx.doi.org/10.1182/blood-2005-03-1189.

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AbstractBone marrow cells (BMCs) could correct some pathologic conditions of the central nervous system (CNS) if these cells would effectively repopulate the brain. One such condition is GM1-gangliosidosis, a neurodegenerative glycosphingolipidosis due to deficiency of lysosomal β-galactosidase (β-gal). In this disease, abnormal build up of GM1-ganglioside in the endoplasmic reticulum of brain cells results in calcium imbalance, induction of an unfolded protein response (UPR), and neuronal apoptosis. These processes are accompanied by the activation/proliferation of microglia and the productio

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Chaudhary, Kiran G., Amruta Tripathy, Puneet Kumar Bagri, and Himanshi Avinash Jain. "Case Series of Primary Testicular Lymphoma: Insights into a Rare Condition." Indian Journal of Case Reports 11, no. 4 (2025): 144–47. https://doi.org/10.32677/ijcr.v11i4.4994.

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Primary testicular lymphoma (PTL) is a rare extranodal type of non-Hodgkin’s lymphoma (NHL), accounting for <5% of testicular malignancies and 1–2% of NHL cases. The most common PTL is diffuse large B-cell lymphoma (DLBCL) type, a highly heterogeneous form of NHL, with a higher incidence in men over 60. Testicular lymphoma frequently recurs in extranodal sites, especially the contralateral testis and central nervous system (CNS), which is a sign of poor prognosis. Given the aggressive nature of testicular DLBCL, multimodal management is required, including orchiectomy, immunochemotherapy wi

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Zhang, Shubo, Xin Zheng, Changsheng Wang, and Gang Wang. "Shear Behavior and Asperity Damage of 3D Rough Joints under CNS Boundary Conditions Based on CZM Simulation." Sustainability 15, no. 6 (2023): 5064. http://dx.doi.org/10.3390/su15065064.

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Although boundary conditions can significantly impact the shear behaviors and asperity damage evolution of jointed rocks, numerical studies on the damage of 3D rough rock joints under the constant normal stiffness (CNS) boundary condition have rarely been reported. In this work, the three-dimensional model of the irregular joint surface is established by using point cloud reconstruction technology. Based on the cohesive zone model (CZM), we simulate the shear behavior of three-dimensional rough rock joints under the CNS boundary condition, which is realized by using embedded spring elements im

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Wilson, Marc-Michel, David C. Henshall, Susan M. Byrne, and Gary P. Brennan. "CHD2-Related CNS Pathologies." International Journal of Molecular Sciences 22, no. 2 (2021): 588. http://dx.doi.org/10.3390/ijms22020588.

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Epileptic encephalopathies (EE) are severe epilepsy syndromes characterized by multiple seizure types, developmental delay and even regression. This class of disorders are increasingly being identified as resulting from de novo genetic mutations including many identified mutations in the family of chromodomain helicase DNA binding (CHD) proteins. In particular, several de novo pathogenic mutations have been identified in the gene encoding chromodomain helicase DNA binding protein 2 (CHD2), a member of the sucrose nonfermenting (SNF-2) protein family of epigenetic regulators. These mutations in

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Wilson, Marc-Michel, David C. Henshall, Susan M. Byrne, and Gary P. Brennan. "CHD2-Related CNS Pathologies." International Journal of Molecular Sciences 22, no. 2 (2021): 588. http://dx.doi.org/10.3390/ijms22020588.

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Epileptic encephalopathies (EE) are severe epilepsy syndromes characterized by multiple seizure types, developmental delay and even regression. This class of disorders are increasingly being identified as resulting from de novo genetic mutations including many identified mutations in the family of chromodomain helicase DNA binding (CHD) proteins. In particular, several de novo pathogenic mutations have been identified in the gene encoding chromodomain helicase DNA binding protein 2 (CHD2), a member of the sucrose nonfermenting (SNF-2) protein family of epigenetic regulators. These mutations in

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Figueroa Rodriguez, Fernando, Kwon Minkyung, Sruthi Jinna, Sohail Farshad, and Francisco Davila. "Rheumatoid Meningoencephalitis: A Feared Condition in the Era of TNF Blockers." Case Reports in Rheumatology 2018 (December 16, 2018): 1–4. http://dx.doi.org/10.1155/2018/4610260.

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Central nervous system (CNS) involvement in rheumatoid arthritis (RA) is uncommon, and most of the times, it is secondary to vasculitic processes or extra-articular rheumatoid nodules. Meningeal involvement is extremely rare. In the literature, there are a few case reports, series, and retrospective studies which have demonstrated the association of rheumatoid (aseptic) meningoencephalitis after starting tumor necrosis factor (TNF) inhibitors. We present a case of rheumatoid meningoencephalitis (RME) in a 52-year-old male with a history of RA on adalimumab who presented with headaches associat

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Longo, Sara, Shanti Esmieu, Alice Pastorello, Katie Waine, Kerstin Baiker, and Giunio Bruto Cherubini. "Cryptococcosis with central nervous system involvement in a dog in the UK: a case report and review of the condition." Companion Animal 24, no. 8 (2019): 414–18. http://dx.doi.org/10.12968/coan.2019.0016.

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This case report describes the clinical presentation, diagnostic findings, treatment and outcome in a dog diagnosed with diffuse cryptococcosis with involvement of the central nervous system (CNS). This represents the fourth case of cryptococcosis with CNS involvement in dogs described in the UK. The dog presented with signs of multifocal brain disorder; investigations, including magnetic resonance imaging, cerebrospinal fluid analysis and serology, revealed cryptococcosis. As previously reported, despite treatment, in our case the outcome was extremely poor. Cryptococcosis is an opportunistic

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Baranouskaja, E. I., S. V. Zhavoronok, G. A. Shishko, and A. Voronetsky. "THE HERPES VIRUS INFECTION INFLUENCE OF THE MOTHER TO CONDITION OF THE NEWBORN." Health and Ecology Issues 1, no. 2 (2004): 55–60. http://dx.doi.org/10.51523/2708-6011.2004-1-2-9.

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Purpose of the objective is to study the influence of the Herpes Virus Infection on the course and the outcome of the pregnancy, pathology of the fetus and newborn. Methods: immunoassay (ELISA), immunofluorescence (MIF), polymerase chain reaction (PCR), statistical. All together 322 pregnant women from the perinatal risk group, whose pregnancy favorable resulted examined. The received results: The Chronically latent Herpes Virus Infection of the mother complicates the pregnancy, conduces to CNS affection in the form of the ischemic-hypoxic encephalopathy of the fetus and newborn. 61% pregnant

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Fry, Brian. "Using stable CNS isotopes to evaluate estuarine fisheries condition and health." Isotopes in Environmental and Health Studies 49, no. 3 (2013): 295–304. http://dx.doi.org/10.1080/10256016.2013.783830.

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Ittiyavirah, Sibi P., and T. Rahees. "Evaluation of psychopharmacological activity of ethyl acetate extract of Sarcostema acidum (Roxb).voigt." Journal of Phytopharmacology 2, no. 5 (2013): 1–7. http://dx.doi.org/10.31254/phyto.2013.2501.

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Herbal medicines are gaining growing interest because of their cost- effective, eco- friendly attributes and true relief from disease condition. Sarcostemma acidum was documented in many folklore practices for various psychiatric conditions. It has been dealt with in detail in “SHRUSHRUTHA SAMHITHA”. Ethyl Acetate Extract of the whole plant Sarcostemma acidum (EASA) was evaluated for psychopharmacological effects, Anti Psychotic, Anxiolytic and CNS inhibitory activity. Anti psychotic effects of EASA was assessed by Condition Avoidance Response and cataleptic Scoring test using pole climbing an

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Kuntz-Melcavage, Kara L., Willard M. Freeman, and Kent E. Vrana. "CNS Genes Implicated in Relapse." Substance Abuse: Research and Treatment 2 (January 2008): SART.S1042. http://dx.doi.org/10.4137/sart.s1042.

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Drug abuse is a condition that impacts not only the individual drug user, but society as a whole. Although prevention of initial drug use is the most effective way to prevent addiction, avoiding relapse is a crucial component of drug addiction recovery. Recent studies suggest that there is a set of genes whose expression is robustly and stably altered following drug use and ensuing abstinence. Such stable changes in gene expression correlate with ultrastructural changes in brain as well as alterations in behavior. As persistent molecular changes, these genes may provide targets for the develop

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Prambudi, Hery, and Supriyatin. "Review of Essential Oil Bioactivity Against Anxiety Symptom." Jurnal Penelitian Pendidikan IPA 11, no. 6 (2025): 1–9. https://doi.org/10.29303/jppipa.v11i6.11512.

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The use of essential oils as complementary therapy for various health conditions, especially those involving the central nervous system (CNS), is gaining increased attention. Anxiety disorder, a common CNS-related condition characterized by excessive worry and fear, is one of the main targets for such therapies. Essential oils from various plants contain bioactive compounds that act on the CNS and exhibit anxiolytic potential. This systematic literature review aimed to assess the anxiolytic bioactivity of essential oils and identify the most effective types used for anxiety reduction. Preclini

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Peeters, Marthe CM, Linda Dirven, Johan AF Koekkoek, Mattijs E. Numans, and Martin JB Taphoorn. "Prediagnostic presentations of glioma in primary care: a case–control study." CNS Oncology 8, no. 3 (2019): CNS44. http://dx.doi.org/10.2217/cns-2019-0015.

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Aim: This study aimed to assess the prevalence of symptoms glioma patients may present with to the general practitioner, and whether these can be distinguished from patients with other CNS disorders or any other condition. Methods: Glioma patients were matched to CNS patients and ‘other controls’ using anonymized general practitioner registries. Prevalences were evaluated in the 5 years prior to diagnosis. Result: CNS patients reported significantly more motor symptoms in the period 60–24 months, (p = 0.039). Moreover, <6 months before diagnosis CNS patients differed significantly in mood d

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Ali, Ahtisham, Salwa Naeem, Maira Mahmood, Muhammad Usman Ajmal, and Agha Shabbir Ali. "AN INFANT WITH A RARE ACQUIRED CNS DISORDER." Journal of Akhtar Saeed Medical & Dental College 06, no. 03 (2024): 120–23. https://doi.org/10.51127/jamdcv06i03cr01.

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Acute disseminated encephalomyelitis (ADEM) or post-infectious encephalomyelitis is a rare neurological condition particularly affecting young children.We report a case of 1-year 1-year-old boy with high grade fever, altered mental status, lower limb weakness and seizures. One week before these symptoms the child had complaints of loose stools and vomiting. His initial reports showed leukopenia, raised acute phase reactants and CSF showed elevated proteins. Clinical evaluation and MRI imaging confirmed the diagnosis of ADEM. Prompt treatment with high dose corticosteroids led to gradual improv

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Setianingsih, Tutik, Danar Purwonugroho, and Yuniar Ponco Prananto. "Influence of Pyrolysis Parameters Using Microwave toward Structural Properties of ZnO/CNS Intermediate and Application of ZnCr2O4/CNS Final Product for Dark Degradation of Pesticide in Wet Paddy Soil." ChemEngineering 5, no. 3 (2021): 58. http://dx.doi.org/10.3390/chemengineering5030058.

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Pesticide is a pollution problem in agriculture. The usage of ZnCr2O4/CNS and H2O2 as additive in liquid fertilizer has potency for catalytic pesticide degradation. Colloid condition is needed for easy spraying. Rice husk and sawdust were used as carbon precursor and ZnCl2 as activator. The biomass–ZnCl2 mixtures were pyrolyzed using microwave (400–800 W, 50 min). The products were dispersed in water by blending then evaporated to obtain ZnO/CNS. The composites were reacted with KOH, CrCl3·6H2O, more ZnCl2, and little water by microwave (600 W, 5 min). The ZnCr2O4/CNS and H2O2 were used for de

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Mitchell-DiCenso, Alba, Gordon Guyatt, Michael Marrin, et al. "A Controlled Trial of Nurse Practitioners in Neonatal Intensive Care." Pediatrics 98, no. 6 (1996): 1143–48. http://dx.doi.org/10.1542/peds.98.6.1143.

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Objective. To compare a clinical nurse specialist/neonatal practitioner (CNS/NP) team with a pediatric resident team in the delivery of neonatal intensive care. Design. Randomized, controlled trial. Setting. A 33-bed tertiary-level neonatal intensive care unit. Patients. Of 821 infants admitted to the neonatal intensive care unit between September 1991 and September 1992, 414 were randomized to care by the CNS/NP team, and 407 were randomized to care by the pediatric resident team. Intervention. Infants assigned to the CNS/NP team were cared for by CNS/NPs during the day and by pediatric resid

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Le Morvan de Sequeira, Charlotte, Charlotte Hengstberger, Paul Enck, and Isabelle Mack. "Effect of Probiotics on Psychiatric Symptoms and Central Nervous System Functions in Human Health and Disease: A Systematic Review and Meta-Analysis." Nutrients 14, no. 3 (2022): 621. http://dx.doi.org/10.3390/nu14030621.

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Background: The gut microbiota impacts on central nervous system (CNS) function via the microbiota–gut–brain axis. Thus, therapeutics targeting the gut microbiota such as probiotics have the potential for improving mental health. This meta-analysis synthesizes the evidence regarding the impacts of probiotics on psychological well-being, psychiatric symptoms and CNS functioning. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were applied for executing this review using the databases PubMed, Web of Science and Cochrane Library. The data were summarized

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Parida, Amitav, Omar Abdel-Mannan, Kshitij Mankad, et al. "Isolated central nervous system familial hemophagocytic lymphohistiocytosis (fHLH) presenting as a mimic of demyelination in children." Multiple Sclerosis Journal 28, no. 4 (2021): 669–75. http://dx.doi.org/10.1177/13524585211053565.

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Isolated central nervous system (CNS) presentations of haemophagocytic lymphohistiocytosis (HLH), traditionally a systemic inflammatory condition, have been reported in adults and children. We identified nine patients with a diagnosis of isolated CNS familial hemophagocytic lymphohistiocytosis (fHLH) with symptom onset <18 years of age, and one asymptomatic sibling. Children with atypical chronic/recurrent CNS inflammation should be considered for immunological and genetic panel testing for fHLH even in the absence of any systemic inflammatory features. Despite haematopoietic stem cell tran

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Anderson, Sharon. "Congenital Nephrotic Syndrome of the Finnish Type in a Dominican Newborn: An Overview and Case Report." Neonatal Network 41, no. 2 (2022): 83–88. http://dx.doi.org/10.1891/11-t-745.

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Congenital nephrotic syndrome of the Finnish type (CNS-FT) is a rare genetic condition that causes massive proteinuria, hypoproteinemia, hypercholesterolemia, and edema that progresses to end-stage renal disease. Symptoms may manifest in utero as fetal hydrops or during the first few days to months of life. This article shares the case of a Dominican infant who presented with CNS-FT. It provides a comprehensive overview of CNS-FT including the underlying genetic cause, prenatal and postnatal diagnostic testing options, and treatment recommendations. It walks the reader through the diagnostic a

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Var, Susanna R., Phoebe Strell, Sether T. Johnson, Alex Roman, Zoey Vasilakos, and Walter C. Low. "Transplanting Microglia for Treating CNS Injuries and Neurological Diseases and Disorders, and Prospects for Generating Exogenic Microglia." Cell Transplantation 32 (January 2023): 096368972311710. http://dx.doi.org/10.1177/09636897231171001.

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Microglia are associated with a wide range of both neuroprotective and neuroinflammatory functions in the central nervous system (CNS) during development and throughout lifespan. Chronically activated and dysfunctional microglia are found in many diseases and disorders, such as Alzheimer’s disease, Parkinson’s disease, and CNS-related injuries, and can accelerate or worsen the condition. Transplantation studies designed to replace and supplement dysfunctional microglia with healthy microglia offer a promising strategy for addressing microglia-mediated neuroinflammation and pathologies. This re

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Maqsood Ahmad Dar, Eijaz Ahmed Bhat, Ajay Kotwal, Mir Sadaqat Hassan Zaffer, and Owvass Hamid Dar. "Clinicoetiological profile and outcome of patients of acute febrile encephalopathy in a tertiary care hospital in New Delhi - A prospective observational study." Asian Journal of Medical Sciences 15, no. 6 (2024): 52–58. https://doi.org/10.71152/ajms.v15i6.3614.

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Background: Acute febrile encephalopathy (AFE) in spite of being a common clinical condition is less known to the general population thereby resulting in delay in seeking medical attention with detrimental consequences. The causes can range from infectious central nervous system (CNS) and systemic diseases to non-infectious conditions such as neuroleptic malignant syndrome, poisoning, and drug overdose. Early diagnosis and prompt medical management can result in good clinical outcome in terms of morbidity and mortality. Aims and Objectives: The aims and objectives are to study the clinical pro

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Dar, Maqsood Ahmad, Eijaz Ahmed Bhat, Ajay Kotwal, Mir Sadaqat Hassan Zaffer, and Owvass Hamid Dar. "Clinicoetiological profile and outcome of patients of acute febrile encephalopathy in a tertiary care hospital in New Delhi - A prospective observational study." Asian Journal of Medical Sciences 15, no. 6 (2024): 52–58. http://dx.doi.org/10.3126/ajms.v15i6.34644.

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Background: Acute febrile encephalopathy (AFE) in spite of being a common clinical condition is less known to the general population thereby resulting in delay in seeking medical attention with detrimental consequences. The causes can range from infectious central nervous system (CNS) and systemic diseases to non-infectious conditions such as neuroleptic malignant syndrome, poisoning, and drug overdose. Early diagnosis and prompt medical management can result in good clinical outcome in terms of morbidity and mortality. Aims and Objectives: The aims and objectives are to study the clinical pro

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Shrestha, R., Shakya Shrestha, O. Millington, J. Brewer, and T. Bushell. "Immune Responses in Neurodegenerative Diseases." Kathmandu University Medical Journal 12, no. 1 (2015): 67–76. http://dx.doi.org/10.3126/kumj.v12i1.13646.

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Neurodegenerative disease is a progressive loss of neurons from central nervous system and has a huge impact on health care system. Various causes have been proposed of which inflammation has been suggested to be a probable key factor in the most of such conditions. The involvement of immune cells including lymphocytes in such diseased condition of the CNS supports this notion. The effective therapy for these diseases has been sought for more than a half century but still lacking such therapy. On such basis this review article has mainly focussed on evidence of the involvement of immune cells

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Fragoso, Yara Dadalti, Tarso Adoni, Joseph Bruno Bidin Brooks, et al. "Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder." Arquivos de Neuro-Psiquiatria 75, no. 2 (2017): 92–95. http://dx.doi.org/10.1590/0004-282x20170001.

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ABSTRACT Superficial siderosis (SS) of the central nervous system (CNS) is a rare and possibly underdiagnosed disorder resulting from chronic or intermittent bleeding into the subarachnoid space, leading to deposition of blood products in the subpial layers of the meninges. Magnetic resonance imaging (MRI) shows a characteristic curvilinear pattern of hypointensity on its blood-sensitive sequences. Methods Series of cases collected from Brazilian centers. Results We studied 13 cases of patients presenting with progressive histories of neurological dysfunction caused by SS-CNS. The most frequen

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Del Principe, Maria Ilaria, Luca Maurillo, Francesco Buccisano, et al. "CENTRAL NERVOUS SYSTEM INVOLVEMENT IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA: DIAGNOSTIC TOOLS, PROPHYLAXIS AND THERAPY." Mediterranean Journal of Hematology and Infectious Diseases 6, no. 1 (2014): e2014075. http://dx.doi.org/10.4084/mjhid.2014.075.

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In adult patients with acute lymphoblastic leukemia (ALL), Central Nervous System (CNS) involvement is associated with a very poor prognosis. The diagnostic assessment of this condition relies on the use of neuroradiology, conventional cytology (CC) and flow cytometry (FCM). Among these approaches, which is the gold standard it is still a matter of debate. Neuroradiology and CC have a limited sensitivity with a higher rate of false negative results. FCM demonstrated a superior sensitivity over CC, particularly when low levels of CNS infiltrating cells are present. Although prospective studies

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Larochelle, Catherine, Imke Metz, Marc-André Lécuyer, et al. "Immunological and pathological characterization of fatal rebound MS activity following natalizumab withdrawal." Multiple Sclerosis Journal 23, no. 1 (2016): 72–81. http://dx.doi.org/10.1177/1352458516641775.

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Background: Severe rebound multiple sclerosis (MS) activity is a life-threatening complication of natalizumab (NTZ) withdrawal, for which pathogenesis and treatment are still unclear. We report the immunological and pathological characterization of a case of central nervous system (CNS) inflammatory demyelination after NTZ discontinuation. Objective: To understand the pathophysiology of this neuroinflammatory condition. Methods: Antemortem blood and cerebrospinal fluid (CSF) analysis was compared with postmortem pathological studies, as well as with novel flow cytometry characterization of imm

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Courtin, E., JC Ouallet, E. Lazaro, M.-L. Martin-Negrier, F. Cohen-Aubart, and P. Duffau. "Isolated CNS Sarcoidosis Versus Systemic Sarcoidosis With CNS Involvement: A Same Disease?" Neurohospitalist 12, no. 2 (2022): 290–94. http://dx.doi.org/10.1177/19418744211030416.

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Neurological involvement occurs in 5 to 15% of patients with sarcoidosis. It rarely represents the sole manifestation of the disease, a condition called isolated neurosarcoidosis. Objectives: To describe patients with definite isolated central neurosarcoidosis. To compare their characteristics to a group of systemic sarcoidosis with central neurologic involvement. Methods: Monocentric retrospective study of all patients presenting with central neurosarcoidosis (NS) over a 10 year period, subsequently divided into 2 groups: isolated neurosarcoidosis (INS) and systemic neurosarcoidosis (SNS). Re

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Sakalecha, Anil Kumar, Parameshwar Keerthi B H, Varun S, and Shivaprasad G Savagave. "Re-Print: An Interesting Case of Disseminated Tuberculoma of Brain and Spinal Cord Type of Study: Case Report." Biomedical Research and Clinical Reviews 5, no. 1 (2021): 01–04. http://dx.doi.org/10.31579/2692-9406/083.

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Tuberculosis is an important public problem worldwide from 19th century. Manifestations of tuberculosis widely classified as pulmonary and extra pulmonary manifestations. Central nervous system (CNS) tuberculosis is a serious condition where patients most often present with seizure. Tuberculoma is one of the CNS manifestations of tuberculosis. The imaging feature of tuberculoma is ring enhancing lesions. Tuberculoma should be differentiated from other diseases with ring enhancing lesions like neurocysticercosis, coccidiomycosis, toxoplasmosis and malignancies.

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Ghareghani, Majid, and Serge Rivest. "Multiple Sclerosis Research Evolves: A Closer Look at Deep Gray Matter, Sexual Function Rehabilitation, and T Regulatory Cells." Journal of Personalized Medicine 14, no. 2 (2024): 202. http://dx.doi.org/10.3390/jpm14020202.

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Garcia-Carretero, Rafael. "Clinical Features and Predictors for Mortality in Neurolisteriosis: An Administrative Data-Based Study." Bacteria 1, no. 1 (2021): 3–11. http://dx.doi.org/10.3390/bacteria1010002.

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Listeriosis is an uncommon and potentially severe zoonotic bacterial infection that usually occurs in outbreaks instead of isolated cases. In recent years, there has been an increase in the incidence of this disease. One of the most severe of its complications involves the central nervous system (CNS) in a condition known as neurolisteriosis. Here, we describe the demographic and clinical features of patients presenting with neurolisteriosis between 2001 and 2015 using administrative data and attempt to identify potential predictors for mortality. We used the Spanish Minimum Basic Data Set at

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Cronin, Elaine Anne. "Actinomycosis: a case report of two patients treated for the condition who required stoma formation." British Journal of Nursing 30, no. 16 (2021): S32—S37. http://dx.doi.org/10.12968/bjon.2021.30.16.s32.

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Actinomycosis is a rare bacterial condition that is seen infrequently and no studies have examined its prevalence or incidence globally. The author, a stoma care clinical nurse specialist (CNS), found herself caring for two such patients 3 weeks apart, both of whom were diagnosed with pelvic actinomycosis. Both patients had been fitted with copper intrauterine devices (IUDs) 10 years previously and were not aware that leaving IUDs in situ for a prolonged period increased their risk of infection. This article gives an overview of the condition, with discussion around the two patients the author

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Mohamed, Nurdiyana, Muhammad Zakwan Yahya, Muttaqillah Najihan Abdul Samat, and Hamzaini Abdul Hamid. "A Rare Case of Isolated Paediatric Central Nervous System Melioidosis: An Imaging Chameleon." International Journal of Research and Scientific Innovation XI, no. XII (2024): 49–54. https://doi.org/10.51244/ijrsi.2024.11120005.

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Burkholderia pseudomallei, the agent of melioidosis, can cause multisystemic infections, including rare cases in the central nervous system (CNS). Isolated CNS melioidosis is particularly rare, with a 3% of cases in long-term study. In this region that is high endemicity, risk factors include direct contact with contaminated soil or water, particularly among individual with immunosuppressive condition. Without timely intervention, CNS melioidosis will lead to high mortality and morbidity rate. Case Presentation: A 6-year-old boy with G6PD deficiency and acute lymphoblastic leukaemia (B cell AL

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