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Journal articles on the topic "Co op AG"

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Yim, Julian W., and Rae Weston. "The characteristics of bioentrepreneurs in the Australian biotechnology industry: A pilot study." Journal of Management & Organization 13, no. 4 (November 2007): 383–406. http://dx.doi.org/10.1017/s1833367200003618.

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AbstractIn order to understand the characteristics of bioentrepreneurs, this paper seeks to identify the entrepreneurial types present in the Australian biotechnology industry by using the four-way psychological typology (Miner 2000) and identifying linkages between the four-way psychological typology and the Big Five model of personality traits. We believe this is a new approach to using psychological typology in the study of entrepreneurship by mapping with the Big Five model of personality traits. Miner's four typological types are ‘personal achievers’ (PA), ‘super sales people’ (SS), ‘expert idea generators’ (EI) and ‘real managers’ (RM). The Big Five factors are extraversion (Ex), stability/emotion stability (Es), agreeableness (Ag), conscientiousness (Co), and openness to experience (Op). By combining the entrepreneurial types and the five-factor personality traits, we can map the linkage relationships as PA-ExEsCoOp; SS-ExAgCoOp; EI-ExEsOp and RM-ExEsCoOp.In this pilot study, we find there are more ‘personal achiever’ and ‘expert idea generator’ bioentrepreneurs in the biotech industry with the linkage relationships of PA-ExEsCoOp and EI-Ex EsOp, which lead us to conclude there are strong demands for bioentrepreneurs with managerial skills, sales and marketing skills, skills in forming strategic alliance with partners and skills in securing the public and private capitals through finance channels such as public listing and venture capital. This implies that if PA entrepreneurs acquired more agreeableness personality traits and EI entrepreneurs also acquired more agreeableness and conscientiousness personality traits they would improve the ability of their businesses to attract more financial investments and form sustainable strategic alliance with partners in the Australian biotechnology industry.
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Yim, Julian W., and Rae Weston. "The characteristics of bioentrepreneurs in the Australian biotechnology industry: A pilot study." Journal of Management & Organization 13, no. 4 (November 2007): 383–406. http://dx.doi.org/10.5172/jmo.2007.13.4.383.

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Abstract:
AbstractIn order to understand the characteristics of bioentrepreneurs, this paper seeks to identify the entrepreneurial types present in the Australian biotechnology industry by using the four-way psychological typology (Miner 2000) and identifying linkages between the four-way psychological typology and the Big Five model of personality traits. We believe this is a new approach to using psychological typology in the study of entrepreneurship by mapping with the Big Five model of personality traits. Miner's four typological types are ‘personal achievers’ (PA), ‘super sales people’ (SS), ‘expert idea generators’ (EI) and ‘real managers’ (RM). The Big Five factors are extraversion (Ex), stability/emotion stability (Es), agreeableness (Ag), conscientiousness (Co), and openness to experience (Op). By combining the entrepreneurial types and the five-factor personality traits, we can map the linkage relationships as PA-ExEsCoOp; SS-ExAgCoOp; EI-ExEsOp and RM-ExEsCoOp.In this pilot study, we find there are more ‘personal achiever’ and ‘expert idea generator’ bioentrepreneurs in the biotech industry with the linkage relationships of PA-ExEsCoOp and EI-Ex EsOp, which lead us to conclude there are strong demands for bioentrepreneurs with managerial skills, sales and marketing skills, skills in forming strategic alliance with partners and skills in securing the public and private capitals through finance channels such as public listing and venture capital. This implies that if PA entrepreneurs acquired more agreeableness personality traits and EI entrepreneurs also acquired more agreeableness and conscientiousness personality traits they would improve the ability of their businesses to attract more financial investments and form sustainable strategic alliance with partners in the Australian biotechnology industry.
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3

Mohamed, Tarek, Tatyana Sycheva, Douglas R. Schneider, Swati R. Chokalingam, and Robert Weinstein. "Inapparent Von Willebrand Disease as the Underlying Cause of Menorrhagia Attributed to Uterine Fibroids." Blood 106, no. 11 (November 16, 2005): 4084. http://dx.doi.org/10.1182/blood.v106.11.4084.4084.

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Abstract Menorrhagia is a public health issue affecting 15% of American women, 300,000 of whom undergo hysterectomy each year. 50% of menorrhagia cases are not explained by gynecological disorders like uterine fibroids but in up to 1/3 of such cases bleeding disorders such as von Willebrand disease (vWd) may be present. No cases have been reported to indicate whether women with fibroids and menorrhagia should be investigated for vWd, particularly when screening tests (aPTT or bleeding time) are normal. We report herein 2 cases which demonstrate that inapparent vWd (normal screening tests) should indeed be sought in certain such cases of menorrhagia. Patient #1 was a 44 y/o African-American woman with severe menorrhagia since menarche, multiple 2 cm fibroids and severe iron deficiency anemia (Hgb 7.9 g/dl; MCV 68.5 FL; ferritin 1 ng/ml). Menstrual periods lasted 7 days. She bled through her clothes the first 1–3 days. Intolerant of oral iron, she required weekly injections of iron sucrose (100 mg) to keep up with menstrual losses. A sister in another state was also known to have menorrhagia. Patient #2 was a 40 year old Caucasian woman with severe menorrhagia since menarche (age 11 years), intramural fibroids and severe iron deficiency anemia (Hb 8.9 g/dl, MCV 64.9 FL, ferritin 4 ng/ml). Menstrual periods lasted 7 days, changing pad every hour for the first 2 days.. She bled through her clothes the first 2–3 days and was unable to keep up with menstrual losses using oral iron. Her younger sister also had menorrhagia. Patient Screening Tests Timing fVIII(%) * vWf Ag (%) * Ristocetin co-factor (%) * vW multimer pattern Comment * reference range: 55–200 #1 PTT 31 sec, BT 6 min, Blood Group O+ Mid cycle 61 54 42 Unknown Normal multimer pattern obtained 30 minutes after pre-op injection of DDAVP and also 4 months post hysterectomy Menses 37 48 23 Type II post hysterectomy 53 52 50 Normal #2 PTT 31.5 sec, BT normal, Blood Group O+ Mid cycle 177 117 120 Normal DDAVP nasal spray shortened menstrual period from 7 days (72 pads) to 5 days(20 pads). Younger sister and nephew subsequently diagnosed with vWd. Menses 74 46 52 Type I These cases illustrate that the assumption that severe menorrhagia is explained by simple anatomical abnormalities such as uterine fibroids may cause a significant hemostatic defect to be overlooked. Even normal screening tests, or vW tests obtained during follicular phase, do not rule out vWd in women with severe menorrhagia. The vW panel should be repeated at the start of menses. Patient #1 demonstrates a hitherto unknown association between uterine fibroids and acquired vWd which was apparently cured by hysterectomy and may suggest a mechanism by which fibroids cause menorrhagia. DDAVP controlled the menorrhagia of Patient #2 and may have done so in Patient #1 as well. Physicians should be alert to the possibility of inapparent vWd as the underlying cause of menorrhagia in women with uterine fibroids. High index of suspicion and careful diagnostic work up may provide an opportunity to avoid needless hysterectomy in some patients.
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4

Rivera-Caravaca, JM, O. Piot, I. Roldan-Rabadan, A. Denis, M. Anguita, J. Mansourati, E. Marijon, et al. "A validation of the 4S-AF scheme in Spanish and French patients from the EORP-AF Long-Term General Registry." EP Europace 23, Supplement_3 (May 1, 2021). http://dx.doi.org/10.1093/europace/euab116.298.

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Abstract Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Abbott Vascular Int. (2011–2014), Amgen Cardiovascular (2009–2018), AstraZeneca (2014–2017), Bayer AG (2009–2018), Boehringer Ingelheim (2009–2019), Boston Scientific (2009–2012), The Bristol Myers Squibb and Pfizer Alliance (2011–2016), The Alliance Daiichi Sankyo Europe GmbH and Eli Lilly and Company (2011–2017), Edwards (2016–2019), Gedeon Richter Plc. (2014–2017), Menarini Int. Op. (2009–2012), MSD-Merck & Co. (2011–2014), Novartis Pharma AG (2014–2017), ResMed (2014–2016), Sanofi (2009–2011), SERVIER (2009–2018). The Atrial Fibrillation NETwork (AFNET), conducting the registry in Germany, received support from The Bristol Myers Squibb/Pfizer Alliance (2014–2018) and the German Centre for Cardiovascular Research (DZHK). Funding from Daiichi-Sankyo and Boehringer-Ingelheim have been received for conducting the registry in Spain. Funding from BMS-Pfizer Alliance was received to support the programme in France Background The 4S-AF scheme (Stroke risk, Symptom severity, Severity of atrial fibrillation [AF] burden, Substrate severity) has recently been described as a novel approach to in-depth characterization of AF, and included in the 2020 European Society of Cardiology guidelines for the management of AF. Purpose In the present study, we validated for the first time the 4S-AF scheme in the Spanish and French cohorts of the EurObservational Research Programme (EORP)-AF Long-Term General Registry. Methods The Spanish and French cohorts of the EORP-AF Long-Term General Registry, were merged and included. The baseline 4S-AF scheme was calculated as follows: Symptom severity (according to EHRA symptom score: 0-2 points), Severity of AF burden (according to AF type: 0-3 points), Substrate severity (according to comorbidities/cardiovascular risk factors: 0-7 points); and related to the primary management strategy (rhythm or rate control). According to the results for these 3 domains, four code colors have been defined. Patients with all domains in "green" should be managed by rhythm control. In patients with one domain in "yellow" or two domains in "green" categories, rhythm control can be attempted. On contrary, for patients with "red" color category, the 4S-AF scheme suggests a rate control strategy. All-cause mortality and the composite of ischemic stroke/transient ischemic attack/systemic embolism, major bleeding and all-cause death, were the primary endpoints. These outcomes were recorded during 1-year of follow-up. Results 1479 patients (36.9% females, median age of 72 [IQR 64-80] years) were included (Table 1). The median 4S-AF scheme score was 5 (IQR 4-7). The 4S-AF scheme, as continuous and as categorical, was associated with the management strategy decided for the patient (both p < 0.001). The predictive performances of the 4S-AF scheme for the actual management strategy were appropriate in its continuous (C-index: 0.77, 95% CI 0.75-0.80) and categorical (C-index: 0.75, 95% CI 0.72-0.78) forms (Figure 1A). Cox regression analyses showed that patients classified as "red" category in the 4S-AF scheme had higher risk of all-cause death (adjusted HR 1.75, 95% CI 1.02-2.99) and composite outcomes (adjusted HR 1.60, 95% CI 1.05-2.44) (Figure 1B). Thus, patients for who the 4S-AF scheme suggests that may be managed by rhythm control (recommended or considered) had a significantly lower risk of these events. Conclusion Characterization of AF by using the 4S-AF scheme may aid in identifying AF patients that would be managed by rhythm or rate control, and could also help in identifying high-risk AF patients for worse clinical outcomes in a ‘real-world’ setting. Abstract Table 1 and Figures 1A-1B
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Books on the topic "Co op AG"

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Otto, Bernd. Der Co op-Skandal: Ein Lehrstück aus der deutschen Wirtschaft. Frankfurt a.M: Campus Verlag, 1996.

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Book chapters on the topic "Co op AG"

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