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Journal articles on the topic 'Co-ordinated Medical Research Fellowships'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Clark, Amelia M., and Brian J. Altman. "Circadian control of macrophages in the tumor microenvironment." Journal of Immunology 208, no. 1_Supplement (2022): 165.06. http://dx.doi.org/10.4049/jimmunol.208.supp.165.06.

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Abstract Introduction All leukocytes tested to date have functional circadian clocks, and nearly every arm of the immune response is subject to circadian regulation. Circadian clocks instruct the time-of-day-dependent, rhythmic expression of genes in a tissue- and cell-specific manner. In macrophages (mΦs), the circadian clock regulates several factors that are critical to executing effective immune responses. Tumor-associated mΦs are major contributors to immune suppression in the tumor microenvironment (TME). Evidence suggests that metabolically stressful factors in the TME such as acidic pH

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Murphy, Martina Cathryn, Naomi D. Parker, Tithi B. Amin, et al. "Educating hematology-oncology fellows about how to communicate with patients about cancer clinical trials: A needs assessment." Journal of Clinical Oncology 42, no. 16_suppl (2024): 9029. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.9029.

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9029 Background: Cancer clinical trials (CCTs) are vital to advancing treatment yet only 5-8% of people with cancer ever participate, with even lower rates among underserved groups. Teaching oncologists in training how to communicate about CCTs may improve the frequency and quality of patient-oncologist communication about CCTs and increase participation. However, little is known about interest in or feasibility of such training during Hematology-Oncology (Hem-Onc) graduate medical education (GME) fellowships. We aimed to determine Hem-Onc fellowship programs’: 1) current practices, needs, and

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Beieler, Alison M., Alison M. Beieler, Leah H. Yoke, et al. "617. Physician Perspective: Utilization of Advanced Practice Providers (APPs) in the ID Workforce." Open Forum Infectious Diseases 7, Supplement_1 (2020): S369—S370. http://dx.doi.org/10.1093/ofid/ofaa439.811.

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Abstract Background Applicants entering Infectious Disease (ID) fellowships are declining and shortages of ID physicians is a challenge recognized by the clinical workforce and Infectious Diseases Society of America (IDSA). There is increased awareness of more Advanced Practice Providers (APPs) being used within ID to expand and extend existing practices. However, little is known about APP utilization, APP clinical scope of practice, specific roles, and opportunities for education. Methods To evaluate physician perspectives on APP utilization in ID, we created an anonymous and voluntary survey

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OGG, JIM, and CATHERINE GORGEON. "Social gerontology in France: historical trends and recent developments." Ageing and Society 23, no. 6 (2003): 797–814. http://dx.doi.org/10.1017/s0144686x03001454.

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Social gerontology, as a distinct discipline, has been slower to develop in France than in Anglo-Saxon countries. Gerontological discourses have been dominated by the medical and physical sciences. At the same time, France has a long tradition of research on ageing that incorporates important social dimensions, particularly in demographic and economic fields. Current developments include research on pensions and related issues such as early-retirement or older people in the labour force; inter-generational relations or family solidarity; disabled elderly people and caring; and ageing among eth

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Toledo, Paloma, Shakir McLean, Lorent Duce, Cynthia A. Wong, Armin Schubert, and Denham S. Ward. "Evaluation of the Foundation for Anesthesia Education and Research Medical Student Anesthesia Research Fellowship Program Participants’ Scholarly Activity and Career Choices." Anesthesiology 124, no. 5 (2016): 1168–73. http://dx.doi.org/10.1097/aln.0000000000001068.

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Abstract Background The Foundation for Anesthesia Education and Research Medical Student Anesthesia Research Fellowship (MSARF) program is an 8-week program that pairs medical students with anesthesiologists performing anesthesia-related research. This study evaluated the proportion of students who published an article from their work, as well as the percentage of students who entered anesthesiology residency programs. Methods A list of previous MSARF participants (2005 to 2012), site, and project information was obtained. Searches for publications were performed using PubMed. The primary outc

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Bansal, Akhil, Joseph Pusey, Rahul Shah, and Abraham Tolley. "Development and evaluation of an extra-curricular programme focussing on high impact career opportunities for medical professionals." PLOS ONE 18, no. 4 (2023): e0284856. http://dx.doi.org/10.1371/journal.pone.0284856.

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Background Many medical professionals seek to do good through their careers, which may involve pursuing non-clinical options such as research, policy, or education in addition to clinical work. Working out which paths will lead to the largest social impact is a challenging question and of interest to many doctors. However, there are few, if any, services that use an impact-oriented framework to support doctors who want to make career decisions based on impact. Objectives To describe the development of an 8-week fellowship programme to introduce medical professionals to careers paths and focus

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Miller, Robin, Catherine Weir, and Steve Gulati. "Transforming primary care: scoping review of research and practice." Journal of Integrated Care 26, no. 3 (2018): 176–88. http://dx.doi.org/10.1108/jica-03-2018-0023.

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Purpose The purpose of this paper is to reflect on research evidence and practice experience of transforming primary care to a more integrated and holistic model. Design/methodology/approach It is based on a scoping review which has been guided by primary care stakeholders and synthesises research evidence and practice experience from ten international case studies. Findings Adopting an inter-professional, community-orientated and population-based primary care model requires a fundamental transformation of thinking about professional roles, relationships and responsibilities. Team-based approa

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Ryan, Una, Sheleigh Lawler, and Simon Reid. "Limiting swimming pool outbreaks of cryptosporidiosis – the roles of regulations, staff, patrons and research." Journal of Water and Health 15, no. 1 (2016): 1–16. http://dx.doi.org/10.2166/wh.2016.160.

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Cryptosporidium is the leading cause of swimming pool outbreaks of gastroenteritis. Transmission occurs through the ingestion of oocysts that are passed in the faeces of an infected person or animal when an accidental faecal release event occurs. Cryptosporidium parasites present specific challenges for infection control as oocysts are highly resistant to chlorine levels used for pool disinfection, infected individuals can shed large numbers of oocysts, there is a long incubation period and shedding of oocysts occurs even after symptom resolution. The purposes of this review are to identify ke

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Ferro, José M., and Patricia Canhão. "Subarachnoid Haemorrhage - Current Thinking and Future Strategy." European Neurological Review 4, no. 2 (2009): 38. http://dx.doi.org/10.17925/enr.2009.04.02.38.

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Subarachnoid haemorrhage (SAH) accounts for only 5% of all strokes, but is responsible for 25% of all fatalities related to stroke. The most important vascular risk factors for SAH are hypertension, smoking and high alcohol intake. One-quarter of patients with acute SAH are not diagnosed at their first medical encounter. To identify the aneurysm causing SAH and allow urgent treatment, angiography must be performed as soon as possible. The most important neurological complications of SAH are re-bleeding, intracerebral haematoma and intraventricular haemorrhage, vasospasm, delayed cerebral ischa

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Vuong, Lan N., Vu N. A. Ho, Tuong M. Ho, et al. "In-vitro maturation of oocytes versus conventional IVF in women with infertility and a high antral follicle count: a randomized non-inferiority controlled trial." Human Reproduction 35, no. 11 (2020): 2537–47. http://dx.doi.org/10.1093/humrep/deaa240.

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Abstract STUDY QUESTION Is one cycle of IVM non-inferior to one cycle of conventional in IVF with respect to live birth rates in women with high antral follicle counts (AFCs)? SUMMARY ANSWER We could not demonstrate non-inferiority of IVM compared with IVF. WHAT IS KNOWN ALREADY IVF with ovarian hyperstimulation has limitations in some subgroups of women at high risk of ovarian stimulation, such as those with polycystic ovary syndrome. IVM is an alternative ART for these women. IVM may be a feasible alternative to IVF in women with a high AFC, but there is a lack of data from randomized clinic

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Lapeña, José Florencio F. "Achievement and Ascription: Fact or Fiction." Philippine Journal of Otolaryngology-Head and Neck Surgery 23, no. 1 (2008): 4. http://dx.doi.org/10.32412/pjohns.v23i1.757.

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“Castles in the clouds, flying by; men will build them till they die; don’t they know it’s all a lie, tumbling castles make them cry; still they try…1”  Identity is shaped by thoughts, ideas, feelings and emotions; expressed in words, actions and expressions; and recorded for posterity in mentifacts and artifacts. “Paper” (or “plastic”) identity, found on various identification cards, electronic databases, resumés and curriculum vitaes, is not necessarily be the same as the “flesh and blood” or real-life identity known best to those with whom face-to-face in

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David, Maya, and Prasannanshu Prasannanshu. "COVID-19 PANDEMIC AND ENDANGERED LANGUAGES." IARS' International Research Journal 11, no. 1 (2021): 03–04. http://dx.doi.org/10.51611/iars.irj.v11i1.2021.148.

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This Special Issue of IARS International Research Journal contains eight articles which investigate diverse aspects of Endangered Languages and COVID-19. The ongoing Covid-19 pandemic has redefined the way we live, work, and think. Consequently, it has become necessary for leaders, specialists, scholars, and academics of various fields to re-examine their positions and research objectives and methodologies in the context of this pandemic. The field of endangered languages is no different: It was soon realised that the effect of the pandemic on endangered languages is far reaching. In man

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Ahmed Alhaneedi, Ghalib, Abduljabbar Alhammoud, Shamsi Hameed, Mohammad Al Ateeq Al Dosari, and Abdullatif Alkhal. "DOES RESTRUCTURING THE RESEARCH CURRICULUM OF ORTHOPEDIC TRAINING PROGRAM AFFECT THE RESEARCH PERFORMANCE? EVIDENCE FROM QATAR." International Journal of Advanced Research 9, no. 01 (2021): 950–56. http://dx.doi.org/10.21474/ijar01/12375.

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Background: The participation of trainees and faculties in the research is an integral part of postgraduate medical training and education. The educational curriculum of the training program should be structured to support the learning of the trainees scholarly activities, address research barriers, foster a culture of inquiry, and improve their research performance. The Accreditation Council for Graduate Medical Education International (ACGME-I) standards include participation in scholarly activities by residents and faculties as an essential requirement of the training program.The possible e

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Hatfield, Laura A., and Sherri Rose. "A conversation with Sherri Rose, winner of the 2020 health policy statistics section mid-career award." Health Services and Outcomes Research Methodology 20, no. 4 (2020): 208–14. http://dx.doi.org/10.1007/s10742-020-00216-6.

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Abstract Sherri Rose, Ph.D. is an associate professor at Stanford University in the Center for Health Policy and Center for Primary Care and Outcomes Research as well as Co-Director of the joint Harvard–Stanford Health Policy Data Science Lab. A renowned expert in machine learning methodology for causal inference and prediction, her applied work has focused on risk adjustment, algorithmic fairness, health program evaluation, and comparative effectiveness research. Dr. Rose’s leadership positions include current roles as Co-Editor of Biostatistics and Chair of the American Statistical Associati

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TERZIDOU, V. "ENDOCRINOLOGY OF PARTURITION AND PREPARATION FOR LABOUR." Fetal and Maternal Medicine Review 20, no. 1 (2009): 67–96. http://dx.doi.org/10.1017/s0965539509002381.

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Parturition is the process leading to expulsion of the fetus from the uterus. It is the result of a co-ordinated interplay between maternal and fetal factors. Despite extensive research the mechanisms that control the length of human pregnancy and signal the onset of labour remain unknown. Preterm labour refers to the onset of labour before 37 completed weeks or 259 days of pregnancy and after the gestation of viability (20–25 weeks, depending on definition). In most developed countries, preterm birth occurs in 5–10% of pregnancies whereas this may rise to 25% in certain developing countries.

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Wade, F. M., N. Pavlakis, I. Receveur, S. Leibman, and G. S. Smith. "The role of cancer Nurse coordinator in foregut malignancy: Workload and costing considerations in the Australian setting." Journal of Clinical Oncology 27, no. 15_suppl (2009): e20559-e20559. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e20559.

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e20559 Background: Foregut (esophageal and gastric) malignancy (FM) encompasses a number of diseases with poor outlook and complex and often morbid treatment. In keeping with world wide trends, the investigation and management of patients with FM is undertaken in the context of a multidisciplinary group consisting medical, nursing and paramedical specialists. Crucial to the delivery of co-ordinated and compassionate care is the Cancer Nurse Co-ordinator (CNC). Further, the CNC is pivotal in ensuring that benchmarks regarding intervals from diagnosis, to multidisciplinary assessment to treatmen

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Sims, Jessica M., Emma Lawrence, Katy Glazer, et al. "Lessons learned from the COVID-19 pandemic about sample access for research in the UK." BMJ Open 12, no. 4 (2022): e047309. http://dx.doi.org/10.1136/bmjopen-2020-047309.

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ObjectiveAnnotated clinical samples taken from patients are a foundation of translational medical research and give mechanistic insight into drug trials. Prior research by the Tissue Directory and Coordination Centre (TDCC) indicated that researchers, particularly those in industry, face many barriers in accessing patient samples. The arrival of the COVID-19 pandemic to the UK produced an immediate and extreme shockwave, which impacted on the ability to undertake all crucial translational research. As a national coordination centre, the TDCC is tasked with improving efficiency in the biobankin

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Pransky, Joanne. "The Pransky interview: Dr Ken Goldberg, Professor, Industrial Engineering and Operations Research, UC Berkeley; Inventor and Artist." Industrial Robot: the international journal of robotics research and application 46, no. 2 (2019): 188–91. http://dx.doi.org/10.1108/ir-02-2019-0026.

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Purpose The following article is a “Q&A interview” conducted by Joanne Pransky of Industrial Robot Journal as a method to impart the combined technological, business, and personal experience of a prominent, robotic industry PhD and inventor regarding his pioneering efforts and the commercialization of bringing a technological invention to market. The paper aims to discuss these issues. Design/methodology/approach The interviewee is Dr Ken Goldberg, an inventor working at the intersection of art, robotics, and social media. He joined the UC Berkeley faculty in 1995 where he is the UC Berkel

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Duffy, J. M. N., H. AlAhwany, S. Bhattacharya, et al. "Developing a core outcome set for future infertility research: an international consensus development study†‡." Human Reproduction 35, no. 12 (2020): 2725–34. http://dx.doi.org/10.1093/humrep/deaa241.

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Abstract STUDY QUESTION Can a core outcome set to standardize outcome selection, collection and reporting across future infertility research be developed? SUMMARY ANSWER A minimum data set, known as a core outcome set, has been developed for randomized controlled trials (RCTs) and systematic reviews evaluating potential treatments for infertility. WHAT IS KNOWN ALREADY Complex issues, including a failure to consider the perspectives of people with fertility problems when selecting outcomes, variations in outcome definitions and the selective reporting of outcomes on the basis of statistical an

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Sageman, Elischka, and Sharleen Cook. "An Outreach Midwifery Program for Homeless, Pregnant Young Women in the Northern Metropolitan Region of Melbourne." Australian Journal of Primary Health 1, no. 1 (1995): 79. http://dx.doi.org/10.1071/py95012.

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In this paper, the background, planning, and implementation of an outreach midwifery service for homeless, pregnant, young women in the northern metropolitan area of Melbourne is described. Research in the north east region of Melbourne had shown the large number of pregnant, homeless, young women, particularly in the West Heidelberg area (McDonald, 1992). Conventional antenatal services were not accessed by these women. They did not attend ante or postnatal classes and frequently missed hospital and medical appointments due to their transient lifestyle and lack of transport. This diminished t

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Williams, Grant Richard, Kathryn E. Weaver, Glenn Jay Lesser, et al. "Capacity to provide specialized care for older adults in community oncology practices: Results of the NCI Community Oncology Research Program (NCORP) Landscape survey." Journal of Clinical Oncology 37, no. 15_suppl (2019): 6539. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.6539.

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6539 Background: American Society of Clinical Oncology guidelines recommend that patients ≥65 years of age starting chemotherapy undergo a geriatric assessment (GA) to inform and guide management; however, little is known about resources available in community oncology practices to facilitate geriatric specialty care and implement these guidelines. Methods: Community oncology practices were electronically surveyed in 2017 regarding the availability of various providers, supportive services, and practice characteristics, as part of a larger survey of cancer care delivery research (CCDR) capacit

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Gravelsins, Laura, Nicole Gervais, Alana Brown, et al. "245 Sleep and cortical thickness are influenced by surgical menopause." Sleep 44, Supplement_2 (2021): A98—A99. http://dx.doi.org/10.1093/sleep/zsab072.244.

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Abstract Introduction Early loss of 17β-estradiol (E2), as experienced by women with bilateral salpingo-oophorectomy (BSO; removal of ovaries and fallopian tubes), is associated with increased prevalence of sleep disorders and greater Alzheimer’s disease (AD) risk. In older adults, poor sleep heightens AD risk; hypoxia increases markers for incipient AD, including circulating Aβ, and is linked to prefrontal cortical thinning. Thus, we wondered: 1) if this at-risk population of middle-aged women with BSO had sleep hypoxia, measured by oxygen desaturation, and 2) whether this related to decrease

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Zhukova, Nataliya, Dilru Habarakada, Caroline Drinkwater, et al. "OTHR-30. Multidisciplinary approach to childhood cancer bio-banking improves enrollment and enables better access to diagnostic and therapeutic studies." Neuro-Oncology 24, Supplement_1 (2022): i153. http://dx.doi.org/10.1093/neuonc/noac079.568.

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Abstract Despite the significant progress made in the multi-modal treatment of childhood malignancies over the last four decades with a concomitantly increased cure rates, the benefit is still largely limited to patients with leukemias, lymphomas and localized non-CNS solid tumors, leaving patients with high-risk non-CNS solid tumours and most CNS malignancies with minimal advancements. More research is critical to understand what drives these cancers and to investigate the best ways to deliver curative therapies. Translational research relies on patient-derived tissue samples, animal models a

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Keinert, Ana, Matheus Ghossain Barbosa, Maria Fernanda Lima-Costa, and Cleusa Pinheiro Ferri. "P8: Depression, diabetes, and healthcare services use – Brazilian Longitudinal Study of Aging (ELSI- Brazil, 2015-2016)." International Psychogeriatrics 36, S1 (2024): 85. http://dx.doi.org/10.1017/s1041610224001911.

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Objectives: Low- and middle-income countries face increasing burden of noncommunicable chronic diseases due to rapid population aging. The Objectives of this study is to estimate the association of co-occurring depression and diabetes with healthcare services utilization in the Brazilian population aged 50 years andolder.Methods: This is an analysis using baseline data of the ELSI-Brazil study. Measurements used were self-reported previous diagnosis for diabetes and a cut-off point of 4 on the CES-D-8 score for depression. Any medical consultations, specialist consultations and hospitalization

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Straus, L. D., P. J. Colvonen, D. Bertenthal, T. C. Neylan, and A. O’Donovan. "1112 Mental Health And Sleep Disorders Are Associated With Elevated C-reactive Protein In Returning Veterans." Sleep 43, Supplement_1 (2020): A423. http://dx.doi.org/10.1093/sleep/zsaa056.1107.

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Abstract Introduction Mental health disorders and sleep disorders are associated with systemic inflammation, which may be a key element linking these highly co-occurring conditions to negative health outcomes. This study used national VA medical records to examine C-reactive protein (CRP) levels in Iraq/Afghanistan veterans based on presence of mental health and/or sleep disorder diagnoses. Methods We examined medical records for 16,576 Iraq/Afghanistan veterans under age 55 who had high-sensitivity CRP results reported. ICD diagnostic codes were used to compare CRP values for: a) veterans wit

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Steel, Michael, Elizabeth Smyth, Hans Vasen, et al. "Ethical, Social and Economic Issues in Familial Breast Cancer: A Compilation of Views from the E.C. Biomed II Demonstration Project." Disease Markers 15, no. 1-3 (1999): 125–31. http://dx.doi.org/10.1155/1999/564893.

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Demand for clinical services for familial breast cancer is continuing to rise across Europe. Service provision is far from uniform and, in most centres, its evolution has been determined by local conditions, specifically by local research interests, rather than by central planning. However, in a number of countries there is evidence of progress towards co-ordinated development and audit of clinics providing risk assessment, counselling, screening and, in some cases, prophylactic intervention. Much important information should emerge from continued observation and comparative assessment of thes

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Duncan, Pamela W. "One Grip a Little Stronger." Physical Therapy 83, no. 11 (2003): 1014–21. http://dx.doi.org/10.1093/ptj/83.11.1014.

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Abstract Pamela W Duncan, PT, PhD, FAPTA Dr Duncan has actively participated in and contributed to physical therapist practice, physical therapist professional education, professional preparation of other health care providers, national policy development related to rehabilitation after stroke and aging, and scientific investigation. She has served several government appointments and provides leadership within several organizations. She served as co-chair of the Consensus Panel on Establishing Guidelines for Stroke Rehabilitation for the Agency for Health Care Policy, Research, and Education.

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Guillen-Ponce, Carmen, Evelina Mocci, Julie Earl, et al. "Spanish national hereditary pancreatic cancer registry (PanFAM)." Journal of Clinical Oncology 30, no. 15_suppl (2012): e12033-e12033. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e12033.

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e12033 Background: Inherited predisposition to Pancreatic Cancer (PC) corresponds 10% of all cases and includes members of families affected with hereditary cancer syndromes as Familial Pancreatic Cancer (FPC), Peutz-Jeghers, familial melanoma, hereditary breast and ovarian cancer, hereditary pancreatitis. An inherited predisposition in early onset PC (≤ 50 years) has also been suggested. We report preliminary data on PanFAM patients and screening of high risk individuals. Methods: PamFAM is a part of the European PANGEN PC case/control study of hereditary PC, co-ordinated by the Ramón y Cajal

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Hoole, Maya, Alison Sheridan, Angela Boyle, et al. "‘Ava’: a Beaker-associated woman from a cist at Achavanich, Highland, and the story of her (re-)discovery and subsequent study." Proceedings of the Society of Antiquaries of Scotland 147 (November 21, 2018): 73–118. http://dx.doi.org/10.9750/psas.147.1250.

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This contribution describes the discovery and subsequent investigation of a cist in a rock-cut pit at Achavanich, Highland. Discovered and excavated in 1987, the cist was found to contain the tightly contracted skeletal remains of a young woman, accompanied by a Beaker, three flint artefacts and a cattle scapula. Initial post excavation work established a date for the skeleton together with details of her age and sex, and preliminary pollen analysis of sediments attaching to the Beaker was undertaken. The findings were never fully published and, upon the death of the excavator, Robert Gourlay,

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Cho, Jonathan C., Wesley D. Kufel, Meghan N. Jeffres, and Elias Chahine. "2539. Characterization of Infectious Diseases Advanced Pharmacy Practice Experiences at United States Colleges of Pharmacy." Open Forum Infectious Diseases 6, Supplement_2 (2019): S882—S883. http://dx.doi.org/10.1093/ofid/ofz360.2217.

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Abstract Background Antimicrobial resistance is a public health crisis. Experiential education about the appropriate use of antimicrobials is necessary to prevent the post-antibiotic era. The purpose of this study was to describe the learning experiences during infectious diseases (ID) advanced pharmacy practice experiences (APPEs) offered by ID pharmacy faculty. Methods A 18-item, cross-sectional, multi-center, electronic survey was distributed via e-mail to ID pharmacy faculty at 124 schools and colleges of pharmacy in the United States. Programs were identified via the Accreditation Council

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Nadhan, Revathy, Ji Hee Ha, Muralidharan Jayaraman, Srishti Kashyap, and Danny N. Dhanasekaran. "Abstract LB039: Ovarian cancer cell-derived exosomal UCA1 reprograms glucose metabolism in stromal fibroblasts." Cancer Research 83, no. 8_Supplement (2023): LB039. http://dx.doi.org/10.1158/1538-7445.am2023-lb039.

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Abstract Tumor progression is stringently regulated by the co-ordinated signaling between the tumor cells and the tumor microenvironment (TME) through diverse autocrine, paracrine and exocrine signaling mechanisms. Recent studies have shown that the exosomes that play a crucial role in the transfer of oncogenic macromolecules and oncometabolites to different cellular components of the TME can be targeted for therapy. Therefore, with the focus on identifying the exosomal long non-coding RNA (lncRNA) that can be therapeutically targeted, we investigated the profile of ovarian cancer cell derived

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Ridgway, L., S. Koushesh, M. Tachrount, et al. "THE FORECAST STUDY: FACTORS PREDICTING PAIN PERSISTENCE IN SCIATICA. AN UPDATE ON BASELINE AND PRELIMINARY LONGITUDINAL DATA." Orthopaedic Proceedings 106-B, SUPP_15 (2024): 16. http://dx.doi.org/10.1302/1358-992x.2024.15.016.

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BackgroundFORECAST is a prospective longitudinal cohort study exploring mechanism-based prognostic factors for pain persistence in sciatica. Here, we share an update on this largest deeply-phenotyped primary care sciatica cohort.Methods/resultsOur cohort includes 180 people with sciatica (score >4 on Stynes’ Sum Score), aged 18–85, within 3 months of symptom onset. Psychosocial factors, self-reported sensory profiling, clinical examination, quantitative sensory testing (QST), biological samples (blood and skin samples), and Magnetic Resonance Neurography of lumbar nerve roots were collected

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Erickson, Alexander, Scott Ravyts, Michael Mitchell, et al. "0414 Pain in Your Day? Get Sleep Treatment Anyway! The Benefits of Behavioral Treatments for Insomnia Despite Pain Symptoms." SLEEP 46, Supplement_1 (2023): A183. http://dx.doi.org/10.1093/sleep/zsad077.0414.

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Abstract Introduction Sleep-related problems and pain affect millions of U.S. adults. Sleep-focused interventions improve both sleep and pain-related outcomes. However, pain can be a barrier to insomnia care due to perceptions that insomnia treatment may not be as effective in the presence of ongoing pain. This study evaluated whether pain severity and pain interference in daily life moderate the effects of behavioral treatments for insomnia on sleep outcomes (e.g., insomnia symptoms, perceived sleep quality, sleep effort, daytime sleepiness). Methods Secondary data analysis was conducted on a

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Office, Editorial. "Medical researchers unite for study on cancer intervention." Advances in Modern Oncology Research 2, no. 4 (2016): 184. http://dx.doi.org/10.18282/amor.v2.i4.158.

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<p><em>We introduce Drs. Antoine Snijders and Jian-Hua Mao, whose article is published in this issue of AMOR and discuss their views on cancer genetics, targeted therapy, and personalized medicine.</em></p><p><em><br /></em></p><p>Having worked together in numerous joint investigations that have yielded significant results, Dr. Snijders and Dr. Mao would most definitely agree that two heads are better than one. “Researchers these days need to have the ability to collaborate across many different disciplines,” said the duo in an exclus

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Nadarajah, R. N. Sugitha. "Combating cancer one step at a time." Advances in Modern Oncology Research 2, no. 5 (2016): 244. http://dx.doi.org/10.18282/amor.v2.i5.179.

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<p>"I graduated from the Faculty of Medicine at Ain Shams University,” says the oncologist, who completed his Bachelor of Medicine and Surgery in 2005 and is now working at the same university as a lecturer in clinical oncology. Ain Shams University, originally known as ‘Ibrahim Pasha’s University’ prides itself in being the third higher education institution to be founded in Egypt. It has produced famous alumni that include current acting Egyptian Prime Minister Sherif Ismail Mohamed and former Egyptian Prime Minister Abd El Aziz Muhammad Hegazi, as well as the noted American modern phi

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Shaffer, Nicholas, Telyn Peterson, and Karen Hentschel-Franks. "1070 Awakening Insights: Increasing Sleep Medicine Education for Psychiatry Residents." SLEEP 47, Supplement_1 (2024): A460. http://dx.doi.org/10.1093/sleep/zsae067.01070.

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Abstract Introduction Sleep is integral to mental health. For example, it is estimated that 40 to 50% of individuals with insomnia have co-occurring mental illness. Despite this, only ~3.31% of current sleep medicine fellows enter from a psychiatry residency, ~4.89% of sleep medicine fellowship alumni are psychiatrists, and 4.25% of sleep faculty members have a psychiatry background. At the present time, the Accreditation Council of Graduate Medical Education has no curriculum requirement for sleep education within psychiatry residency programs. A past study has shown that less than 40% of psy

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Gardner, Mike, Sasha Shepperd, Mary Godfrey, et al. "Comprehensive Geriatric Assessment in hospital and hospital-at-home settings: a mixed-methods study." Health Services and Delivery Research 7, no. 10 (2019): 1–206. http://dx.doi.org/10.3310/hsdr07100.

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BackgroundThe Comprehensive Geriatric Assessment (CGA) is a multidisciplinary process that determines a frail older person’s medical, functional, psychological and social capability to ensure that they have a co-ordinated plan for treatment and follow-up.ObjectivesTo improve our understanding of the effectiveness, cost-effectiveness and implementation of the CGA across hospital and hospital-at-home settings.MethodsWe used a variety of methods. We updated a Cochrane review of randomised trials of the CGA in hospital for older people aged ≥ 65 years, conducted a national survey of community CGA,

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MD Yusof, M. Y., J. Robinson, V. Davies, et al. "OP0190 COMPREHENSIVE GENETIC AND FUNCTIONAL ANALYSES OF Fc GAMMA RECEPTORS EXPLAIN RESPONSE TO RITUXIMAB THERAPY FOR AUTOIMMUNE RHEUMATIC DISEASES." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 126–27. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2615.

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BackgroundRituximab is widely used to treat rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) but clinical response varies. Efficacy is determined by the efficiency of depletion, which may depend on a variety of Fc gamma receptor (FcγR)-dependent mechanisms. Previous research was limited by complexity of the FCGR locus, not integrating copy number variation with functional SNP, and small sample size.ObjectivesThe study objectives were to assess the effect of the full range of FcγRs variants on depletion, clinical response and functional effect on NK-cell-mediated killing in two

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Holness, Dave. "Improving Access to Justice through Law Graduate Post-Study Community Service in South Africa." Potchefstroom Electronic Law Journal 23 (January 16, 2020): 1–25. http://dx.doi.org/10.17159/1727-3781/2020/v23i0a5968.

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Access to justice for all in South Africa, as most clearly set out in sections 34 and 35 of the Constitution of the Republic of South Africa, 1996, is necessary to realise various other fundamental rights and to improve living standards. There are insufficient free legal services available to the indigent in South Africa, especially in civil matters, thereby often making meaningful access to justice unattainable. This study considers possible approaches, challenges and opportunities for law graduate community service in South Africa (hereinafter "community service") to expand the ambit and imp

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Trost, Barry M., Olivier Dirat, Joseph Dudash, Jr., and Erik J. Hembre. "An Asymmetric Synthesis of C-2-epi-Hygromycin A We thank the National Science Foundation and the National Institute of Health, General Medical Sciences, for their generous support of our programs. O.D. thanks the Association pour la Recherche contre le Cancer (ARC) for a postdoctoral fellowship. Mass spectra were kindly provided by the Mass Spectrometry Facility, University of San Francisco, supported by the NIH Division of Research Resources." Angewandte Chemie International Edition 40, no. 19 (2001): 3658. http://dx.doi.org/10.1002/1521-3773(20011001)40:19<3658::aid-anie3658>3.0.co;2-2.

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Brown, Louise Clare, Hashim U. Ahmed, Rita Faria, et al. "Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study." Health Technology Assessment 22, no. 39 (2018): 1–176. http://dx.doi.org/10.3310/hta22390.

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Background Men with suspected prostate cancer usually undergo transrectal ultrasound (TRUS)-guided prostate biopsy. TRUS-guided biopsy can cause side effects and has relatively poor diagnostic accuracy. Multiparametric magnetic resonance imaging (mpMRI) used as a triage test might allow men to avoid unnecessary TRUS-guided biopsy and improve diagnostic accuracy. Objectives To (1) assess the ability of mpMRI to identify men who can safely avoid unnecessary biopsy, (2) assess the ability of the mpMRI-based pathway to improve the rate of detection of clinically significant (CS) cancer compared wi

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Kirchhoff, Jan H., Chaoyang Dai, and Gregory C. Fu. "A Method for Palladium-Catalyzed Cross-Couplings of Simple Alkyl Chlorides: Suzuki Reactions Catalyzed by [Pd2(dba)3]/PCy3 dba=(E,E)-dibenzylideneacetone, Cy=cyclohexyl. We thank Dr. Matthew R. Netherton for helpful discussions and Johnson Matthey Inc. for supplying palladium compounds. Support has been provided by the Deutsche Akademie der Naturforscher Leopoldina (Leopoldina fellowship to J.H.K., BMBF-LPD 9901/8-48), Bristol-Myers Squibb, the National Institutes of Health (National Institute of General Medical Sciences, R01-GM62871), the Natural Sciences and Engineering Research Council of Canada (postdoctoral fellowship to C.D.), and Novartis. Funding for the MIT Department of Chemistry Instrumentation Facility has been provided in part by NSF CHE-9808061 and NSF DBI-9729592." Angewandte Chemie 114, no. 11 (2002): 2025. http://dx.doi.org/10.1002/1521-3757(20020603)114:11<2025::aid-ange2025>3.0.co;2-w.

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Kirchhoff, Jan H., Chaoyang Dai, and Gregory C. Fu. "A Method for Palladium-Catalyzed Cross-Couplings of Simple Alkyl Chlorides: Suzuki Reactions Catalyzed by [Pd2(dba)3]/PCy3 dba=(E,E)-dibenzylideneacetone, Cy=cyclohexyl. We thank Dr. Matthew R. Netherton for helpful discussions and Johnson Matthey Inc. for supplying palladium compounds. Support has been provided by the Deutsche Akademie der Naturforscher Leopoldina (Leopoldina fellowship to J.H.K., BMBF-LPD 9901/8-48), Bristol-Myers Squibb, the National Institutes of Health (National Institute of General Medical Sciences, R01-GM62871), the Natural Sciences and Engineering Research Council of Canada (postdoctoral fellowship to C.D.), and Novartis. Funding for the MIT Department of Chemistry Instrumentation Facility has been provided in part by NSF CHE-9808061 and NSF DBI-9729592." Angewandte Chemie International Edition 41, no. 11 (2002): 1945. http://dx.doi.org/10.1002/1521-3773(20020603)41:11<1945::aid-anie1945>3.0.co;2-7.

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Tan, Tiffany C. Y., Saabah B. Mahbub, Jared M. Campbell, et al. "Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo." Human Reproduction 37, no. 1 (2021): 14–29. http://dx.doi.org/10.1093/humrep/deab233.

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Abstract STUDY QUESTION Can label-free, non-invasive optical imaging by hyperspectral autofluorescence microscopy discern between euploid and aneuploid cells within the inner cell mass (ICM) of the mouse preimplantation embryo? SUMMARY ANSWER Hyperspectral autofluorescence microscopy enables discrimination between euploid and aneuploid ICM in mouse embryos. WHAT IS KNOWN ALREADY Euploid/aneuploid mosaicism affects up to 17.3% of human blastocyst embryos with trophectoderm biopsy or spent media currently utilized to diagnose aneuploidy and mosaicism in clinical in vitro fertilization. Based on

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De Moortel, Deborah, Michelle C. Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, and Víctor Gonzalez. "Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe." Scandinavian Journal of Work, Environment & Health 51, no. 4 (2025): 259–64. https://doi.org/10.5271/sjweh.4238.

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Digitalization, green transitions, and demographic change are transforming societies and economies across Europe. These shifts are giving rise to new forms of work (eg, hybrid work, gig economy jobs) and reshaping management and work organization practices (eg, through algorithmic decision-making or digital monitoring of worker performance). While such developments offer important opportunities to improve sustainability, flexibility, and efficiency, they also present challenges for ensuring healthy and equitable working conditions—especially if workplace policies and practices do not keep pace

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Barsoum, Rashad S. "The story of the African Association of Nephrology (AFRAN)." African Journal of Nephrology 20, no. 1 (2017). http://dx.doi.org/10.21804/20-1-1650.

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The African Association of Nephrology was founded in Cairo on 28 February 1987, during the ISN-sponsored “African Kidney and Electrolytes Conference”, being hosted and co-sponsored by the Egyptian Society of Nephrology. Twenty-five physicians interested in kidney disease, from 13 African countries, constituted the core assembly that selected a steering committee composed of five members, representing the five geographical zones in Africa. The committee proposed the name the African Association of Nephrology (AFRAN), approved its logo, defined its mission, and drafted its constitution. All were

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Omer, Wafa. "Level-8 Ph.D. Programs In Medical Sciences: High Time For The Higher Education Commission (HEC) Of Pakistan To Establish A Medical Wing." Journal of Rawalpindi Medical College 28, no. 1 (2024). http://dx.doi.org/10.37939/jrmc.v28i1.2577.

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Medical Universities in Pakistan are growing in number at a fast pace. According to the database of the Pakistan Medical Commission 2021, at present Pakistan is home to 224 million people, 30 medical universities, and 176 public and private sector medical and dental schools.1 Most of these medical colleges have now transformed into autonomous medical universities while some remain affiliated with renowned medical universities.2 Some of the relatively newer medical universities in Punjab are Rawalpindi Medical University, Fatima Jinnah Medical University, King Edward Medical University, Nishtar

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Cocchi, Massimo, Lucio Tonello, and Fabio Gabrielli. "Molecular contiguity between man and animal: the cutting-edge studies carried out by Paolo Sotgiu Institute, L.U.de.S. University, Lugano, Switzerland." Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale 87, no. 1 (2014). http://dx.doi.org/10.4081/jbr.2014.2126.

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Recent research on the contiguity between man and animal provides strong evidence for the studies carried out by <em>Paolo Sotgiu</em> Institute for Research in Quantitative &amp; Quantum Psychiatry &amp; Cardiology, L.U.de.S. University, Lugano, Switzerland, in collaboration with the Department of Veterinary Medical Science, University of Bologna, Italy. The works, co- ordinated by Prof. Massimo Cocchi &ndash; <em>Paolo Sotgiu</em> Institute Scientific Director &ndash; have underlined this continuity, especially as to the relationship between man and do

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Price, Adam D., Bilal W. Nasim, Kelsey B. Montgomery, et al. "A Multi-institutional Study From the United States Resident Operative Experience Consortium Examining Factors Associated With Exposure and Pursuit of Colorectal Fellowship Following General Surgery Residency." Diseases of the Colon & Rectum, February 7, 2025. https://doi.org/10.1097/dcr.0000000000003671.

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BACKGROUND: Colon and rectal surgery is a popular fellowship following general surgery residency. The impact of a resident’s colon and rectal surgery experience during residency may impact their career trajectory and pursuit of colon and rectal surgery. OBJECTIVE: This study aims to identify individual and program factors associated with matriculation into colon and rectal surgery fellowship compared to other career trajectories. DESIGN: An analysis of case logs and demographic data from graduates of 19 accredited general surgery residency programs from the Accreditation Council for Graduate M

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Lu, Clara, Kathryn Chan, Leslie Martin, and Nadia Fairbairn. "“We need all hands on deck”: characterizing addiction medicine training in Canada—a mixed methods study of fellowship program directors." Addiction Science & Clinical Practice 20, no. 1 (2025). https://doi.org/10.1186/s13722-025-00543-4.

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Abstract Background Addiction Medicine training in Canada has evolved substantially in the last few years with the establishment of accreditation standards and several new fellowship programs. The novelty of these formal training programs, created in response to complex and ever-expanding clinical needs in Addiction Medicine, creates unique educational circumstances that must be understood to support future growth. This study characterizes the current state of these postgraduate training programs in Canada through the perspectives of Program Directors (PDs). Methods This study is a mixed metho

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