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Dissertations / Theses on the topic 'Cochlea'

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1

Giese, Arnaud. "Régulation de la protéine centrale de la polarité planaire cellulaire Vangl2 dans l’organe de Corti." Thesis, Bordeaux 2, 2010. http://www.theses.fr/2010BOR21761/document.

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Outre leur polarité apico-basale, certaines cellules épithéliales développent une seconde polarité, appelée Polarité Planaire Cellulaire (PCP). L'axe de la PCP est orienté perpendiculairement à l'axe de polarité apico-basale et régit l'orientation uniforme de certaines structures, comme les poils ou cils, non seulement à l'échelle de la cellule mais également au sein du tissu. L'épithélium cochléaire est l'un des meilleurs modèles d'étude de PCP chez les mammifères. En effet, les cellules neuro-épitheliales qui le composent, soutenues par des cellules de soutien, présentent à leur apex, des to
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2

Ku, Emery Mayon. "Modelling the human cochlea." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/64535/.

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One of the salient features of the human cochlea is the incredible dynamic range it possesses—the loudest bearable sound is 10,000,000 times greater than the softest detectable sound; this is in part due to an active process. More than twelve thousand hairlike cells known as outer hair cells are believed to expand and contract in time to amplify cochlear motions. However, the cochlea’s response is more than just the sum of its parts: the local properties of outer hair cells can have unexpected consequences for the global behaviour of the system. One such consequence is the existence of otoacou
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3

van, der Vyver Johannes Petrus. "A biomorphic electronic Hopf cochlea /." Zürich : ETH, 2006. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=16941.

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4

Morell, Ybarz Maria. "Ultrastructural analysis of odontocete cochlea." Doctoral thesis, Universitat Politècnica de Catalunya, 2012. http://hdl.handle.net/10803/125113.

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The morphological study of the Odontocete organ of Corti including possible pathological features resulting from sound over-exposure, represent a key conservation issue to assess the effects of acoustic pollution on marine ecosystems. Through the collaboration with stranding networks belonging to 26 countries, 150 ears from 13 species of Odontocetes were processed. In this dissertation, we present a standard protocol to 1) compare the ultrastructure of the cochlea in several Odontocete species and 2) investigate possible damage as a consequence of sound exposure, using scanning (SEM) and trans
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5

Jia, Huan. "Stratégies pharmacologiques pour la prévention de la fibrose intra-cochléaire." Thesis, Montpellier 1, 2012. http://www.theses.fr/2012MON1T001.

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L'implantation cochléaire reste à ce jour le seul moyen capable de restaurer la perception auditive chez les personnes présentant une surdité sévère ou profonde en échec d'appareillage conventionnel. Son principe repose sur la stimulation électrique directe des neurones auditifs de la cochlée par un faisceau d'électrode inséré dans l'oreille interne. Malgré les progrès réalisés dans le manufacturage des électrodes et dans la technique chirurgicale, le geste d'insertion du faisceau d'électrode demeure traumatique. Ce traumatisme est souvent responsable de la perte de l'audition résiduelle sur l
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6

Edelmann, Karola. "Richtungshören bei Kindern mit bilateralen Cochlea-Implantaten im Vergleich zu Kindern mit unilateralem Cochlea-Implantat." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976294052.

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7

Fragnière, Eric. "Analogue VLSI emulation of the cochlea /." Lausanne, 1998. http://library.epfl.ch/theses/?nr=1796.

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8

Blomkvist, Anna, and Anna Fritz-Sundström. "Språkutveckling hos barn med cochlea implantat." Thesis, Örebro University, School of Humanities, Education and Social Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-9919.

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9

Shiraishi, Hisako. "Design of an Analog VLSI Cochlea." University of Sydney. Electrical and Information Engineering, 2003. http://hdl.handle.net/2123/556.

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The cochlea is an organ which extracts frequency information from the input sound wave. It also produces nerve signals, which are further analysed by the brain and ultimately lead to perception of the sound. An existing model of the cochlea by Fragni`ere is first analysed by simulation. This passive model is found to have the properties that the living cochlea does in terms of the frequency response. An analog VLSI circuit implementation of this cochlear model in CMOS weak inversion is proposed, using log-domain filters in current domain. It is fabricated on a chip and a measurement of a bas
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10

Kallweit, Nicole [Verfasser]. "Laserinduzierte Stimulation der Cochlea / Nicole Kallweit." Garbsen : TEWISS - Technik und Wissen GmbH, 2019. http://d-nb.info/1176156241/34.

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11

Evans, Jared. "Piezoelectric-Based, Self-Sustaining Artificial Cochlea." Wright State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=wright1389196704.

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12

Vignali, Dario. "Modelling nonlinear interactions within the cochlea." Thesis, University of Southampton, 2017. https://eprints.soton.ac.uk/412704/.

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The auditory system has a wide dynamic range and remarkable selectivity, due partly to the nonlinear processing within the cochlea. Modelling the performance of the cochlea is a way to gain insight into how it operates and to better understand its mechanical structure, whose arrangement generates nonlinear phenomena. A box model with nonlinear micromechanics was simulated using the state space method and the quasi-linear method to understand nonlinear dynamic interactions within the cochlea. The results from the quasi-linear model were essential for obtaining cochlear compression curves, which
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13

Fasquelle, Lydie. "TMPRSS3 dont les mutations sont responsables des surdités humaines DFNB8/10, joue un rôle crucial dans la survie des cellules sensorielles lors de l'entrée en fonction cochléaire : caractérisation du modèle animal et identification des voies de signalisation impliquées." Thesis, Montpellier 1, 2011. http://www.theses.fr/2011MON1T026.

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TMPRSS3 est une sérine protéase mutée dans les surdités humaines DFNB8/10. Pour déterminer le rôle de cette protéine dans la physiologie cochléaire, nous avons généré puis caractérisé le phénotype auditif d'un modèle murin mimant la pathologie humaine. Les souris mutantes homozygotes sont profondément sourdes, due à une perte rapide et complète des cellules sensorielles cochléaires au moment de leur entrée en fonction. Afin de caractériser les mécanismes moléculaires responsables de la perte de ces cellules, nous avons comparé le protéome de souris sauvages et mutantes par des gels en 2-dimens
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14

Newbold, Carrie. "Electrode tissue interface : development and findings of an in vitro model /." Connect to thesis, 2006. http://repository.unimelb.edu.au/10187/1692.

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In the period immediately following the implantation of a cochlear implant electrode array within the cochlear environment, the power required to stimulate the auditory nerve at preset current levels increases. This rise is due to increases in electrode impedance which in turn is suggested to be a result of tissue growth around the electrode array. The foreign body response initiated by the immune system encapsulates the array in a matrix of fibrous tissue, separating the electrode array from the rest of the body. A second change in electrode impedance occurs with the onset of electrical st
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15

O'Beirne, Greg A. "Mathematical modelling and electrophysiological monitoring of the regulation of cochlear amplification." University of Western Australia. School of Biomedical and Chemical Sciences, 2005. http://theses.library.uwa.edu.au/adt-WU2006.0115.

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[Truncated abstract] The cochlea presumably possesses a number of regulatory mechanisms to maintain cochlear sensitivity in the face of disturbances to its function. Evidence for such mechanisms can be found in the time-course of the recovery of CAP thresholds during experimental manipulations, and in observations of slow oscillations in cochlear micromechanics following exposure to low-frequency tones (the “bounce phenomenon”) and other perturbations. To increase our understanding of these oscillatory processes within the cochlea, and OHCs in particular, investigations into cochlear regulatio
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16

Knobloch, Marie [Verfasser]. "Harmoniewahrnehmung mit dem Cochlea-Implantat / Marie Knobloch." Magdeburg : Universitätsbibliothek, 2018. http://d-nb.info/1165650568/34.

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17

Brass, David Neil. "Stimulus frequency otoacoustic emissions and cochlea function." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261775.

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18

Mullaley, Christopher John. "Modelling current flow in the mammalian cochlea." Thesis, University College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440459.

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19

John, Gabriela Christina [Verfasser]. "Otolithenfunktionsstörung nach Cochlea-Implantation / Gabriela Christina John." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2015. http://d-nb.info/1071088084/34.

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20

Ni, Guangjian. "Fluid coupling and waves in the cochlea." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/348820/.

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The cochlea plays an important role in human hearing. Its basic function is to map sounds of different frequencies onto corresponding characteristic positions on the basilar membrane, BM. When sounds enter the fluid-filled cochlea, deflections of the BM occur due to pressure differences between the cochlear fluid chambers. These deflections propagate along the cochlea to a frequency-dependent characteristic position and then decay away rapidly. The mechanics of the cochlea are modelled using both analytic and numerical models. In this thesis, the passive response of the cochlea is analysed, co
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21

Mann, Zoe Francesca. "Mitochondrial function in the neonatal rat cochlea." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1446285/.

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The cochlea is a specialised structure that contains the cells responsible for transducing mechanical sound stimuli into neural code within the auditory nerve. Mutations in the mitochondrial genome have been associated with hearing loss, suggesting that they play a key role in cochlear physiology. Alongside ATP production, mitochondria are also intimately involved in processes such as calcium homeostasis and the regulation of cell death. The precise role for mitochondria in inner ear physiology is at present poorly defined. I used neonatal cochlear explants and confocal microscopy to study asp
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22

Hey, Matthias. "Kanaltrennung bei hochratiger sequentieller pulsatiler Elektrostimulation der Cochlea." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=967060745.

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23

Louza, Julia Palo Rodrigues. "Zum Einfluss der Cochlea Implantation auf das Vestibularorgan." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-124603.

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24

Vonier, Andreas. "Cochlea-implantierte Kinder gehörloser bzw. hochgradig hörgeschädigter Eltern." Heidelberg Median-Verl, 2008. http://deposit.d-nb.de/cgi-bin/dokserv?id=3117018&prov=M&dokv̲ar=1&doke̲xt=htm.

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25

Fleischer, Mario. "Mehrfeldmodellierung und Simulation der äußeren Haarsinneszelle der Cochlea." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-100717.

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Das Innenohr des Säugetieres ist ein hochspezialisiertes sensorisches System, das durch ein komplexes mechanisches Verhalten gekennzeichnet ist. Neben der komplizierten Morphometrie und Geometrie kommen auch dem richtungsabhängigen Materialverhalten eine wesentliche Bedeutung zu. Es zeigt sich, daß im Cortischen Organ mit der äußeren Haarsinneszelle ein Zelltyp vorliegt, der durch seine physikalischen Eigenschaften das Gesamtverhalten des Innenohres maßgeblich beeinflußt. Wie jede tierische Zelle weist die äußere Haarsinneszelle als biomechanisches System eine heterogene Mikrostruktur auf. Vom
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26

Pan, Shuokai. "Cochlea modelling and its application to speech processing." Thesis, University of Southampton, 2018. https://eprints.soton.ac.uk/427156/.

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Models of the cochlea provide a valuable tool for both better understanding its mechanics and also as an inspiration for many speech processing algorithms. Realistic modelling of the cochlea can be computationally demanding, however, which limits its applicability in signal processing applications. To mitigate this issue, an efficient numerical method has been proposed for performing time domain simulations, based on a nonlinear state space formulation. This model has then been contrasted with another type of cochlear model, that is established from a cascade of digital filters. A comparison o
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27

Zhak, Serhii M. "Modeling and design of an active silicon cochlea." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45863.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2008.<br>Includes bibliographical references.<br>Silicon cochleas are inspired by the biological cochlea and perform efficient spectrum analysis: They realize a bank of constant-Q Nth-order filters with O(N) efficiency rather than O(N²) efficiency due to their use of an exponentially tapered filter cascade. They are useful in speech-recognition front ends, cochlear implants, and hearing aids, especially as architectures for improving spectral analysis in noisy environments and for perf
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28

Schulze-Gattermann, Heide. "Kosten-Nutzen-Analyse der Cochlea-Implantation bei Kindern /." Berlin : Springer, 2002. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=009735549&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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29

Wong, Paul Chun Hymn. "High Fidelity Bioelectric Modelling of the Implanted Cochlea." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14445.

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Cochlear implants are medical devices that can restore sound perception in individuals with sensorineural hearing loss (SHL). Since their inception, improvements in performance have largely been driven by advances in signal processing, but progress has plateaued for almost a decade. This suggests that there is a bottleneck at the electrode-tissue interface, which is responsible for enacting the biophysical changes that govern neuronal recruitment. Understanding this interface is difficult because the cochlea is small, intricate, and difficult to access. As such, researchers have turned to mode
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30

Mammano, Fabio. "Biophysics of the Cochlea. Theory, Experiments and Applications." Doctoral thesis, SISSA, 1992. http://hdl.handle.net/20.500.11767/4438.

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This work attempts to bring together theoretical and experimental aspects of cochlear biophysics. In both cases, the focus is on the relationship between the motility of outer hair cells and the filtering properties of the basilar membrane, as this seems the key for understanding the functioning of the peripheral auditory system. From the theoretical side, the hydrodynamics of the cochlea is studied in detail. A possible mechanism for coupling the outer hair cells to the mechanics of the basilar membrane is proposed and analysed mathematically. From the experimental side, the effects of
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31

Jäger, Wanje. "Physiological aspects of cochlear excitation and neurotransmitter release /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-3294-8/.

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32

Cheng, Jun. "Signal processing approaches on otoacoustic emissions /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4058-4.

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33

McMahon, Catherine. "The mechanisms underlying normal spike activity of the primary afferent synapse in the cochlea and its dysfunction : an investigation of the possible mechanisms of peripheral tinnitus and auditory neuropathy." University of Western Australia. School of Biomedical and Chemical Sciences, 2004. http://theses.library.uwa.edu.au/adt-WU2003.0034.

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[Truncated abstract] One of the problems in researching tinnitus is that it has often been assumed that the physiological mechanisms underlying the tinnitus percept cannot be objectively measured. Nonetheless, it is generally accepted that the percept results from altered spontaneous neural activity at some site along the auditory pathway, although it is still debated whether it is produced by: synchronisation of activity of adjacent neurones; a change in the temporal pattern of activity of individual neurones; or an increase in the spontaneous firing rate per se. Similarly, it is possible tha
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34

Waleka, Oliver Julian [Verfasser]. "Hörrehabilitation bei einseitiger Ertaubung mittels Cochlea-Implantat: Der Einfluss der subjektiven Ertaubungsdauer auf das postoperative Einsilberverstehen nach Cochlea-Implantation / Oliver Julian Waleka." Mainz : Universitätsbibliothek der Johannes Gutenberg-Universität Mainz, 2020. http://d-nb.info/1224810813/34.

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35

Wachtlin, Bianka, and Blanca Schäfer. "Phonologische Bewusstheit bei deutschsprachigen Kindern mit bilateraler Cochlea-Implantat Versorgung : eine Pilotstudie." Universität Potsdam, 2014. http://opus.kobv.de/ubp/volltexte/2014/7148/.

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36

Wright, A. "Structural changes in the human cochlea during drug treatment." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371567.

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37

Huss, M. "Dead regions in the cochlea : diagnosis and perceptual consequences." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604839.

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“Threshold equalising noise” (TEN) was designed to produce approximately equal masked thresholds for all signal frequencies for people without DRs. When the signal falls inside a DR and is therefore detected via neurones with characteristic frequencies different from the signal frequency, the masked threshold is unusually high. the TEN test was validated by comparison with psychophysical tuning curves and was found to be an appropriate clinical tool for the identification of DR. Hearing-impaired subjects who do not perceive pure tones with a clear pitch were often assumed to have DRs. A system
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38

Lahne, Manuela. "Damage-induced signalling mechanisms in the neonatal rat cochlea." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1444911/.

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Sound overstimulation and exposure to ototoxic drugs damage cochlear hair cells (HCs) and cause their death. The surrounding support cells maintain an epithelial barrier and the appropriate physiological environment for surviving HCs during pathological conditions. Coordination of this homeostatic process requires cellular signalling. However, the signalling events that are activated during damage in the mammalian cochlea, are poorly understood. Neonatal rat cochlear explants were subjected to mechanical damage or exposed to neomycin - an ototoxin. Mechanical damage triggered the immediate pro
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39

Hüttenbrink, Karl-Bernd, Thomas Zahnert, Uwe Vogel, and Gert Hofmann. "Biologic Fixation of the Electrode Cable of Cochlea Implants." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-135236.

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Objectives: To verify the necessity for special surgical techniques or clips for fixation of the electrode cable of a cochlea implant against dislocation, and to test the stability of postoperative biologic cicatrization as the sole and solid anchoring of the cable. Material: Temporal bone experiments with a simulated connective tissue sheath around conventional (Med El Combi 40+) and prototype (profiled surface) electrode cables. Results and Conclusions: The electrode cable is anchored securely in a sheath of scar tissue, since unphysiologic loads are needed for pulling it out of its anchorag
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40

De, Boer Jessica. "Electrical properties of Deiters cells of the mammalian cochlea." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397252.

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41

Page, Scott Lawrence. "Sound-induced micromechanical motions in an isolated cochlea preparation." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37926.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006.<br>Includes bibliographical references (p. 44-45).<br>The mechanical processes at work within the organ of Corti can be greatly elucidated by measuring both radial motions and traveling-wave behavior of structures within this organ in response to sound stimuli. To enable such measurements, we have developed a new preparation for observing three-dimensional motions of micromechanical structures in the apical region of an isolated gerbil cochlea. The cochlea is submerged in a low-chl
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42

Aranyosi, Alexander James 1970. "Measuring sound-induced motions of the alligator lizard cochlea." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/16829.

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Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 2002.<br>Includes bibliographical references (p. 219-235).<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>The sensitivity and frequency selectivity of the hearing sense are determined primarily by mechanical properties of the cochlea. These mechanical properties are poorly understood in any species. This thesis contributes to our understanding of cochlear mechanics by presenting measu
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43

Alkhairy, Samiya Ashraf. "An analytic model of the Cochlea and functional interpretations." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/113732.

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Thesis: Ph. D. in Biomedical Engineering, Harvard-MIT Program in Health Sciences and Technology, 2017.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 120-125).<br>The cochlea is part of the peripheral auditory system that has unique and intriguing features - for example it acts as a wave-based frequency analyzer and amplifies traveling waves. The human cochlea is particularly interesting d
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44

Andor, Daniel Ardó. "Energy transport, reflections and noise in the active cochlea." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615187.

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45

Burghard, Alice [Verfasser]. "Einflussfaktoren auf proliferative Vorgänge nach Cochlea Implantation / Alice Burghard." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2013. http://d-nb.info/1046662295/34.

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46

Hüttenbrink, Karl-Bernd, Thomas Zahnert, Uwe Vogel, and Gert Hofmann. "Biologic Fixation of the Electrode Cable of Cochlea Implants." Karger, 2000. https://tud.qucosa.de/id/qucosa%3A27630.

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Objectives: To verify the necessity for special surgical techniques or clips for fixation of the electrode cable of a cochlea implant against dislocation, and to test the stability of postoperative biologic cicatrization as the sole and solid anchoring of the cable. Material: Temporal bone experiments with a simulated connective tissue sheath around conventional (Med El Combi 40+) and prototype (profiled surface) electrode cables. Results and Conclusions: The electrode cable is anchored securely in a sheath of scar tissue, since unphysiologic loads are needed for pulling it out of its anchorag
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47

Weddell, Thomas David. "Mechanisms of excitation and amplification in the mammalian cochlea." Thesis, University of Brighton, 2013. https://research.brighton.ac.uk/en/studentTheses/0f9db6ef-c538-4db9-a714-ea04154959fa.

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Mechanisms of cochlea excitation and amplification were investigated experimentally across a range of mammalian species. Distortion product otoacoustic emissions (DPOAEs) are used to clinically assess hearing. DPOAEs recorded from the ears of human subjects in the presence of a low frequency, high level tone were compared with similar recordings made from guinea pigs. Both guinea pig and human data were found to originate from a common cochlear nonlinearity; the Boltzmann model of DPOAE generation at the output of a spatially localised single-saturating non-linearity. Accordingly, the guinea p
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48

Ghosh, Sumana. "CANNABINOID RECEPTORS (CB) IN COCHLEA: CHARACTERIZATION AND OTOPROTECTIVE FUNCTIONS." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/dissertations/1486.

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Endocannabinoid (eCB) system is composed of endogenous CB ligands including anandamide (AEA) and 2-Arachidonyl glycerol (2-AG), enzymes involved in their biosynthesis and degradation such as diacylglycerol lipase-α (DAGL- α), and CB receptors. Primarily, there are three types of CB receptors - CB receptor 1(CB1), CB receptor 2 (CB2) and non CB1 non CB2 types of CB receptor (e.g. GPR, TRPV1) and they belong to G-protein (Gi/o) coupled receptors (GPCR) family.CB1 receptors are abundant in the brain where they modulate neuronal activities. On the other hand, CB2 receptors are predominantly expre
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49

Tobin, Mélanie. "Gradients in the mechanical properties of auditory hair cells." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCC183/document.

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Notre capacité à communiquer et à apprécier la musique repose sur une discrimination de fréquences couvrant une large gamme de fréquences sonores. Cette propriété résulte de cellules mécanosensorielles « ciliées », qui sont réglées pour répondre de façon maximale à une fréquence caractéristique qui varie monotoniquement le long de l’axe de l’organe auditif, la cochlée. Les mécanismes cellulaires et moléculaires qui définissent la fréquence d’une cellule ciliée et régulent sa valeur pour différentes cellules afin de couvrir la gamme auditive demeurent néanmoins inconnus. Notre hypothèse de trav
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50

Berninger, Erik. "Quinine as a model for the study of cochlear hearing loss in humans /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4272-2/.

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