Academic literature on the topic 'Cochlear mechanics'

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Journal articles on the topic "Cochlear mechanics"

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Ni, Guangjian, Stephen J. Elliott, Mohammad Ayat, and Paul D. Teal. "Modelling Cochlear Mechanics." BioMed Research International 2014 (2014): 1–42. http://dx.doi.org/10.1155/2014/150637.

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The cochlea plays a crucial role in mammal hearing. The basic function of the cochlea is to map sounds of different frequencies onto corresponding characteristic positions on the basilar membrane (BM). Sounds enter the fluid-filled cochlea and cause deflection of the BM due to pressure differences between the cochlear fluid chambers. These deflections travel along the cochlea, increasing in amplitude, until a frequency-dependent characteristic position and then decay away rapidly. The hair cells can detect these deflections and encode them as neural signals. Modelling the mechanics of the cochlea is of help in interpreting experimental observations and also can provide predictions of the results of experiments that cannot currently be performed due to technical limitations. This paper focuses on reviewing the numerical modelling of the mechanical and electrical processes in the cochlea, which include fluid coupling, micromechanics, the cochlear amplifier, nonlinearity, and electrical coupling.
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Robles, Luis, and Mario A. Ruggero. "Mechanics of the Mammalian Cochlea." Physiological Reviews 81, no. 3 (July 1, 2001): 1305–52. http://dx.doi.org/10.1152/physrev.2001.81.3.1305.

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In mammals, environmental sounds stimulate the auditory receptor, the cochlea, via vibrations of the stapes, the innermost of the middle ear ossicles. These vibrations produce displacement waves that travel on the elongated and spirally wound basilar membrane (BM). As they travel, waves grow in amplitude, reaching a maximum and then dying out. The location of maximum BM motion is a function of stimulus frequency, with high-frequency waves being localized to the “base” of the cochlea (near the stapes) and low-frequency waves approaching the “apex” of the cochlea. Thus each cochlear site has a characteristic frequency (CF), to which it responds maximally. BM vibrations produce motion of hair cell stereocilia, which gates stereociliar transduction channels leading to the generation of hair cell receptor potentials and the excitation of afferent auditory nerve fibers. At the base of the cochlea, BM motion exhibits a CF-specific and level-dependent compressive nonlinearity such that responses to low-level, near-CF stimuli are sensitive and sharply frequency-tuned and responses to intense stimuli are insensitive and poorly tuned. The high sensitivity and sharp-frequency tuning, as well as compression and other nonlinearities (two-tone suppression and intermodulation distortion), are highly labile, indicating the presence in normal cochleae of a positive feedback from the organ of Corti, the “cochlear amplifier.” This mechanism involves forces generated by the outer hair cells and controlled, directly or indirectly, by their transduction currents. At the apex of the cochlea, nonlinearities appear to be less prominent than at the base, perhaps implying that the cochlear amplifier plays a lesser role in determining apical mechanical responses to sound. Whether at the base or the apex, the properties of BM vibration adequately account for most frequency-specific properties of the responses to sound of auditory nerve fibers.
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Zheng, Jiefu, Niranjan Deo, Yuan Zou, Karl Grosh, and Alfred L. Nuttall. "Chlorpromazine Alters Cochlear Mechanics and Amplification: In Vivo Evidence for a Role of Stiffness Modulation in the Organ of Corti." Journal of Neurophysiology 97, no. 2 (February 2007): 994–1004. http://dx.doi.org/10.1152/jn.00774.2006.

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Although prestin-mediated outer hair cell (OHC) electromotility provides mechanical force for sound amplification in the mammalian cochlea, proper OHC stiffness is required to maintain normal electromotility and to transmit mechanical force to the basilar membrane (BM). To investigate the in vivo role of OHC stiffness in cochlear amplification, chlorpromazine (CPZ), an antipsychotic drug that alters OHC lateral wall biophysics, was infused into the cochleae in living guinea pigs. The effects of CPZ on cochlear amplification and OHC electromotility were observed by measuring the acoustically and electrically evoked BM motions. CPZ significantly reduced cochlear amplification as measured by a decline of the acoustically evoked BM motion near the best frequency (BF) accompanied by a loss of nonlinearity and broadened tuning. It also substantially reduced electrically evoked BM vibration near the BF and at frequencies above BF (≤80 kHz). The high-frequency notch (near 50 kHz) in the electrically evoked BM response shifted toward higher frequency in a CPZ concentration-dependent manner with a corresponding phase change. In contrast, salicylate resulted in a shift in this notch toward lower frequency. These results indicate that CPZ reduces OHC-mediated cochlear amplification probably via its effects on the mechanics of the OHC plasma membrane rather than via a direct effect on the OHC motor, prestin. Through modeling, we propose that with a combined OHC somatic and hair bundle forcing, the upward-shift of the ∼50-kHz notch in the electrically-evoked BM motion may indicate stiffness increase of the OHCs that is responsible for the reduced cochlear amplification.
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Dallos, Peter. "Cochlear mechanics." Journal of the Acoustical Society of America 87, S1 (May 1990): S1. http://dx.doi.org/10.1121/1.2028114.

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Dong, Wei, and Nigel P. Cooper. "An experimental study into the acousto-mechanical effects of invading the cochlea." Journal of The Royal Society Interface 3, no. 9 (March 2, 2006): 561–71. http://dx.doi.org/10.1098/rsif.2006.0117.

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The active and nonlinear mechanical processing of sound that takes place in the mammalian cochlea is fundamental to our sense of hearing. We have investigated the effects of opening the cochlea in order to make experimental observations of this processing. Using an optically transparent window that permits laser interferometric access to the apical turn of the guinea-pig cochlea, we show that the acousto-mechanical transfer functions of the sealed (i.e. near intact) cochlea are considerably simpler than those of the unsealed cochlea. Comparison of our results with those of others suggests that most previous investigations of apical cochlear mechanics have been made under unsealed conditions, and are therefore likely to have misrepresented the filtering of low-frequency sounds in the cochlea. The mechanical filtering that is apparent in the apical turns of sealed cochleae also differs from the filtering seen in individual auditory nerve fibres with similar characteristic frequencies. As previous studies have shown the neural and mechanical tuning of the basal cochlea to be almost identical, we conclude that the strategies used to process low frequency sounds in the apical turns of the cochlea might differ fundamentally from those used to process high frequency sounds in the basal turns.
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Kamble,, Mrs Nirmala N., and Dr V. R. Mankar. "Identifying Diabetic Parameters in Cochlear Mechanics and Models." International Journal of Engineering Research 3, no. 9 (September 1, 2014): 521–25. http://dx.doi.org/10.17950/ijer/v3s9/901.

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Zweig, George. "Linear cochlear mechanics." Journal of the Acoustical Society of America 138, no. 2 (August 2015): 1102–21. http://dx.doi.org/10.1121/1.4922326.

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Zweig, George. "Nonlinear cochlear mechanics." Journal of the Acoustical Society of America 139, no. 5 (May 2016): 2561–78. http://dx.doi.org/10.1121/1.4941249.

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Epp, Bastian, Jesko L. Verhey, and Manfred Mauermann. "Modeling cochlear dynamics: Interrelation between cochlea mechanics and psychoacousticsa)." Journal of the Acoustical Society of America 128, no. 4 (October 2010): 1870–83. http://dx.doi.org/10.1121/1.3479755.

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Kaufmann-Yehezkely, Michal, Ronen Perez, and Haim Sohmer. "Implications from cochlear implant insertion for cochlear mechanics." Cochlear Implants International 21, no. 5 (May 14, 2020): 292–94. http://dx.doi.org/10.1080/14670100.2020.1757225.

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Dissertations / Theses on the topic "Cochlear mechanics"

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Sun, Luyang. "Inverse methods in cochlear mechanics." Thesis, University of Southampton, 2016. https://eprints.soton.ac.uk/413460/.

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Cochlear modelling is used to provide insight into the physical mechanics of the cochlea. The complicated, three dimensional geometry of the fluid chambers in the cochlea is often represented in models of its mechanics by a box with a uniform area along its length. The first part of this thesis is concerned with the development of a tapered box model of the cochlea, in which the geometry of the cochlea is assumed to vary in a linear way along its length. Previous measurements of the variation in area of the two fluid chambers along the length of the cochlea in various mammals has been used to calculate a linear fit to the variation in the "effective area" that determines the 1D fluid coupling. The width of the basilar membrane is also assumed to vary linearly along the length of the model. The analytic form of the 1D fluid pressure distribution due to elemental BM motion is derived for this tapered box model, together with the added mass due to near field acoustic coupling. The coupled response in the 1D and 3D, uniform and tapered box model of passive cochlea can then be readily calculated. Although the form of the fluid coupling are very different in the uniform and tapered box models, the distribution of the basilar membrane vibration in the coupled models are very similar. The second part of the thesis is concerned with deriving the parameters of cochlear models from measured data using inverse methods. Previous inverse methods are first reviewed before a novel direct method is introduced, based on modelling the poles and zeros of the micromechanical response. This is compared with other inverse methods, using previously measured data on basilar membrane vibration in the cochlea, and relatively simple models are shown to provide a good fit to the data.
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Kolston, Paul Johannes. "Towards a better understanding of cochlear mechanics: A new cochlear model." Thesis, University of Canterbury. Electrical and Electronic Engineering, 1989. http://hdl.handle.net/10092/6653.

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Improving our understanding of cochlear mechanics requires the analysis of cochlear models. In the formulation of such models, it is necessary to make assumptions as to the relative importance of the many structures which comprise the cochlear partition. Data on the relative motion of these structures are virtually non-existent, and so the accuracy of many of the assumptions made is questionable. The bulk of the content of this thesis relates to the formulation and analysis of a new type of linear mechanical cochlear model. The new assumptions made in the formulation of the model are justified on the basis of the structure of the cochlear partition. The apparent realism of the model (both its structure and certain features of its response) seriously questions the hypothesis that response tuning and changes in response resulting from trauma prove the existence of active processes in the cochlea. Furthermore, arguments are presented that question the validity of using the presence of spontaneous otoacoustic emissions to justify the existence of active processes in cochlear tuning. The new model suggests that the complicated structural geometry of the cochlear partition (particularly the organ of Corti) must be incorporated in a model before conclusions relating to real cochlear behaviour can be drawn from it. In particular, the model suggests that a mechanical second filter exists in the cochlea, from rather broad tuning in the pectinate zone of the basilar membrane to sharper, neural-like tuning in the arcuate zone. It is concluded that the only way to properly check the validity of cochlear models is to obtain more experimental data pertaining to the relative motions of the various components that constitute the cochlear partition. Before this is done, we should not place too much faith in our present (alleged) understanding of cochlear mechanics. Also presented in this thesis are new modelling techniques for improving the realism of electrical transmission line cochlear models: the ability to include longitudinal and radial mechanical coupling, multidimensional fluid motion and stick-slip friction. It is shown that the inclusion of mechanical coupling and two-dimensional fluid motion in the new cochlear model has a predictable (and trivial) effect on-its response. The use of the stick-slip friction modelling technique is illustrated by means of two simple examples.
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Watts, Lloyd Mead Carver. "Cochlear mechanics : analysis and analog VLSI /." Diss., Pasadena, Calif. : California Institute of Technology, 1993. http://resolver.caltech.edu/CaltechETD:etd-07022004-115127.

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Bell, James Andrew, and andrew bell@anu edu au. "The Underwater Piano: A Resonance Theory of Cochlear Mechanics." The Australian National University. Research School of Biological Sciences, 2006. http://thesis.anu.edu.au./public/adt-ANU20080706.141018.

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This thesis takes a fresh approach to cochlear mechanics. Over the last quarter of a century, we have learnt that the cochlea is active and highly tuned, observations suggesting that something may be resonating. Rather than accepting the standard traveling wave interpretation, here I investigate whether a resonance theory of some kind can be applied to this remarkable behaviour.¶ A historical survey of resonance theories is first conducted, and advantages and drawbacks examined. A corresponding look at the traveling wave theory includes a listing of its short-comings.¶ A new model of the cochlea is put forward that exhibits inherently high tuning. The surface acoustic wave (SAW) model suggests that the three rows of outer hair cells (OHCs) interact in a similar way to the interdigital transducers of an electronic SAW device. Analytic equations are developed to describe the conjectured interactions between rows of active OHCs in which each cell is treated as a point source of expanding wavefronts. Motion of a cell launches a wave that is sensed by the stereocilia of neighbouring cells, producing positive feedback. Numerical calculations confirm that this arrangement provides sharp tuning when the feedback gain is set just below oscillation threshold.¶ A major requirement of the SAW model is that the waves carrying the feedback have slow speed (5-200 mm/s) and high dispersion. A wave type with the required properties is identified - a symmetric Lloyd-Redwood wave (or squirting wave) - and the physical properties of the organ of Corti are shown to well match those required by theory.¶ The squirting wave mechanism may provide a second filter for a primary traveling wave stimulus, or stand-alone tuning in a pure resonance model. In both, cyclic activity of squirting waves leads to standing waves, and this provides a physical rendering of the cochlear amplifier. In keeping with pure resonance, this thesis proposes that OHCs react to the fast pressure wave rather than to bending of stereocilia induced by a traveling wave. Investigation of literature on OHC ultrastructure reveals anatomical features consistent with them being pressure detectors: they possess a cuticular pore (a small compliant spot in an otherwise rigid cell body) and a spherical body within (Hensens body) that could be compressible. I conclude that OHCs are dual detectors, sensing displacement at high intensities and pressure at low. Thus, the conventional traveling wave could operate at high levels and resonance at levels dominated by the cochlear amplifier. ¶ The latter picture accords with the description due to Gold (1987) that the cochlea is an ‘underwater piano’ - a bank of strings that are highly tuned despite immersion in liquid.¶ An autocorrelation analysis of the distinctive outer hair cell geometry shows trends that support the SAW model. In particular, it explains why maximum distortion occurs at a ratio of the two primaries of about 1.2. This ratio also produces near-integer ratios in certain hair-cell alignments, suggesting that music may have a cochlear basis.¶ The thesis concludes with an evaluation and proposals to experimentally test its validity.
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Ryan, Marie Siobhan. "The influence of neural activity on cochlear mechanics in humans." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404594.

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Sellon, Jonathan Blake. "The functional role of tectorial membrane poroelasticity in cochlear mechanics." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/107287.

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Thesis: Ph. D., Harvard-MIT Program in Health Sciences and Technology, 2016.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 121-132).
The tectorial membrane (TM) is an extracellular matrix that overlies the mechanically sensitive hair bundles of sensory receptor cells in the inner ear. Based on this strategic position, it has long been accepted that the TM plays a critical role in the stimulation of sensory hair cells. Early measurements demonstrated elastic properties of the TM and suggested that the TM is resonant. More recent measurements have shown that longitudinal coupling of the TM generates traveling waves that contribute to cochlear tuning. Here we show the importance of (1) viscosity in controlling the spread of excitation in TM traveling waves, as well as the importance of matrix porosity in determining (2) the viscosity of genetically modified TMs, and (3) local interactions with hair bundles. To understand the longitudinal spread of mechanical excitation via TM traveling waves, we develop chemical manipulations that systematically and reversibly alter TM stiffness and viscosity. Increasing TM viscosity or decreasing stiffness reduces longitudinal spread of mechanical excitation, thereby coupling a smaller range of best frequencies, which would sharpen tuning. In contrast, increasing viscous loss or decreasing stiffness would tend to broaden tuning in resonance based TM models. Thus, TM wave and resonance mechanisms are fundamentally different in the way they control frequency selectivity. To understand the molecular origin of TM viscosity, we investigate traveling waves in genetically modified TMs. We show that nanoscale pores of TectaY1870C/+ TMs are significantly larger than those of Tectb -/- TMs. The larger pore size reduces shear viscosity, thereby reducing traveling wave speed and increasing spread of excitation. These results demonstrate the previously unrecognized importance of TM porosity in cochlear tuning. To understand how TM porosity affects the local interaction between the TM and hair cells, we apply oscillatory forces to the TM with spherical probe tips. The effective stiffness of the TM is small at low frequencies where the porous matrix and surrounding fluid can move independently. By contrast, the effective stiffness of the TM is large at high frequencies, where these two phases are entrained by viscosity to move together. Interestingly, the transition frequency is in the audio frequency range only for hair bundle sized tips. Furthermore, the transition region is characterized by increased phase lead between the stimulus force and applied displacement that may play an essential role in the stability of micromechanical feedback paths and ultimately the sensitivity of hearing. In conclusion, these results show that traveling wave properties and local interactions with the hair bundles depend critically on TM porosity, thus fundamentally changing the way we think about molecular mechanisms underlying cochlear frequency selectivity and sensitivity.
by Jonathan Blake Sellon.
Ph. D.
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Williams, Deirdre Mary. "The effect of the auditory efferents on acoustic distortion products in human subjects." Thesis, University of Sussex, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240554.

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Arcand, Benjamin Y. "An active surgical positioning device for a cochlear implant electrode array /." Available online. Click here, 2005. http://sunshine.lib.mtu.edu/ETD/DISS/arcandb/diss.pdf.

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Ghaffari, Roozbeh 1979. "The functional role of the mammalian tectorial membrane in the cochlear mechanics." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43876.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.
Includes bibliographical references (p. 101-110).
Sound-evoked vibrations transmitted into the mammalian cochlea produce traveling waves that provide the mechanical tuning necessary for spectral decomposition of sound. These traveling waves of motion propagate along the basilar membrane (BM) and ultimately stimulate the mechano-sensory receptors. The tectorial membrane (TM) plays a key role in this stimulation process, but its mechanical function remains unclear. Here we show that the TM supports traveling waves that are an intrinsic feature of its visco-elastic structure. Radial forces applied at audio frequencies (1-20 kHz) to isolated TM segments generate longitudinally propagating waves on the TM with velocities similar to those of the BM traveling wave near its best frequency (BF) place. We compute the dynamic shear storage modulus and shear viscosity of the TM from the propagation velocity of the waves and show that segments of the TM from the basal turn are stiffer than apical segments are. Analysis of loading effects of hair bundle stiffness, the limbal attachment of the TM, and viscous damping in the subtectorial space suggests that TM traveling waves can occur in vivo. To test how TM waves may participate in cochlear function, we investigated waves in genetically modified mice lacking beta-tectorin, a glycoprotein found exclusively in the TM. Tectb-/- mutant mice were previously shown to exhibit significant loss of cochlear sensitivity at low frequencies and sharpened frequency tuning compared to wild types. We show that the spatial extent and propagation velocity of TM traveling waves are significantly reduced in Tectb-/- mice compared to wild types, consistent with the concept that there is a reduction in the spread of excitation via TM waves and less TM wave interaction with the BM traveling wave in Tectb-/- mice.
(cont.) The differences in TM wave properties between mutants and wild types arise from changes to the mechanical properties of the TM; mutant TMs are significantly less stiff than wild type TMs are. Our results show the presence of a traveling wave mechanism through the TM that can functionally couple a significant longitudinal extent of the cochlea and may interact with the BM wave, suggesting that TM waves are crucial for cochlear sensitivity and tuning.
by Roozbeh Ghaffari.
Ph.D.
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Hill, Jennifer Clare. "The relationship between auditory efferent function and frequency selectivity in man." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313735.

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Books on the topic "Cochlear mechanics"

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Duifhuis, Hendrikus. Cochlear Mechanics. Boston, MA: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4419-6117-4.

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International Symposium on Cochlear Mechanics and Otoacoustic Emissions (1985 Rome, Italy). Cochlear mechanics and otoacoustic emissions. Stockholm, Sweden: Distributed by the Almqvist & Wiksell Periodical Co., 1986.

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International Symposium on Cochlear Mechanics and Otoacoustic Emissions (1985 Rome, Italy). Cochlear mechanics and otoacoustic emissions. Stockholm, Sweden: Distributed by Almqvist & Wiksell Periodical Co., 1986.

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service), SpringerLink (Online, ed. Cochlear Mechanics: Introduction to a Time Domain Analysis of the Nonlinear Cochlea. Boston, MA: Springer US, 2012.

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F, Grandori, Cianfrone G, and Kemp D. T, eds. Cochlear mechanisms and otoacoustic emissions: 2nd International Symposium on Cochlear Mechanics and Otoacoustic Emissions. Basel: Karger, 1990.

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Williamstown, Mass ). Mechanics of Hearing Workshop (11th 2011. What fire is in mine ears: Progress in auditory biomechanics : proceedings of the 11th International Mechanics of Hearing Workshop, Williamstown, Massachusetts, 16-22 July 2011 / editors, Christopher A. Shera, Elizabeth S. Olson. Melville, N.Y: American Institute of Physics, 2011.

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H, Wada, ed. Proceedings of the International Symposium on Recent Developments in Auditory Mechanics. Singapore: World Scientific, 2000.

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Mechanics, and Biophysics of Hearing (Conference) (1990 University of Wisconsin Madison WI). The Mechanics and biophysics of hearing: Proceedings of a conference held at the University of Wisconsin, Madison, WI, June 25-29, 1990. Berlin: Springer-Verlag, 1990.

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Bohnke, Frank. Cochlear Mechanics (Orl). Not Avail, 1999.

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De Boer, Egbert, and Alfred L. Nuttall. Cochlear mechanics, tuning, non-linearities. Oxford University Press, 2010. http://dx.doi.org/10.1093/oxfordhb/9780199233397.013.0005.

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Book chapters on the topic "Cochlear mechanics"

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Duifhuis, Hendrikus. "Emerging Cochlear Mechanics." In Cochlear Mechanics, 33–63. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_3.

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Duifhuis, Hendrikus. "A PTPV Response Collection." In Cochlear Mechanics, 237–58. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_10.

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Duifhuis, Hendrikus. "Developments from 1950 to 1980." In Cochlear Mechanics, 21–31. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_2.

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Duifhuis, Hendrikus. "Nonlinear Auditory Phenomena (I) Knowledge Around 1980." In Cochlear Mechanics, 67–93. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_4.

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Duifhuis, Hendrikus. "Modeling the Nonlinear Cochlea." In Cochlear Mechanics, 95–146. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_5.

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Duifhuis, Hendrikus. "Results." In Cochlear Mechanics, 149–74. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_6.

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Duifhuis, Hendrikus. "Applications and Perspective." In Cochlear Mechanics, 175–93. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_7.

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Duifhuis, Hendrikus. "Basic Linear Tools." In Cochlear Mechanics, 197–220. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_8.

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Duifhuis, Hendrikus. "Nonlinear Tools." In Cochlear Mechanics, 221–35. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_9.

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Duifhuis, Hendrikus. "Historical Introduction." In Cochlear Mechanics, 3–19. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-6117-4_1.

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Conference papers on the topic "Cochlear mechanics"

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Verma, Sunil, Suresh Singh Naruka, and Ameet Kishore. "Mechanics involved in cochlear implantation." In 2015 International Conference on Futuristic Trends on Computational Analysis and Knowledge Management (ABLAZE). IEEE, 2015. http://dx.doi.org/10.1109/ablaze.2015.7155001.

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ZWEIG, G. "CELLULAR COOPERATION IN COCHLEAR MECHANICS." In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812704931_0045.

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Cooper, Nigel P., John J. Guinan, Christopher A. Shera, and Elizabeth S. Olson. "Efferent Insights into Cochlear Mechanics." In WHAT FIRE IS IN MINE EARS: PROGRESS IN AUDITORY BIOMECHANICS: Proceedings of the 11th International Mechanics of Hearing Workshop. AIP, 2011. http://dx.doi.org/10.1063/1.3658118.

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GARDNER-MEDWIN, A. R. "COCHLEAR MECHANICS: A SIDEWAYS LOOK." In Proceedings of the 10th International Workshop on the Mechanics of Hearing. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789812833785_0053.

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"MODELLING THE COCHLEAR AMPLIFIER AND THE COCHLEA'S DYNAMICS." In Proceedings of the 10th International Workshop on the Mechanics of Hearing. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789812833785_others05.

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van der Heijden, Marcel, and Corstiaen P. C. Versteegh. "Questioning cochlear amplification." In MECHANICS OF HEARING: PROTEIN TO PERCEPTION: Proceedings of the 12th International Workshop on the Mechanics of Hearing. AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4939347.

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Meaud, Julien, Thomas Bowling, and Charlsie Lemons. "Computational Modeling of Spontaneous Otoacoustic Emissions by the Mammalian Cochlea." In ASME 2018 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dscc2018-9044.

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The mammalian cochlea is a sensory system with high sensitivity, sharp frequency selectivity and a broad dynamic range. These characteristics are due to the active nonlinear feedback by outer hair cells. Because it is an active nonlinear system, the cochlea sometimes emits spontaneous otoacoustic emissions (SOAEs) that are generated in the absence of any external stimulus due to the emergence of limit cycle oscillations. In this work, we use a computational physics-based model of the mammalian cochlea to investigate the generation of SOAEs. This model includes a three-dimensional model of the fluid mechanics in the cochlear ducts, a micromechanical model for the vibrations of the cochlear structures, and a realistic model of outer hair cell biophysics. Direct simulations of SOAEs in the time-domain demonstrate that the model is able to capture key experimental observations regarding SOAEs. Parametric studies and analysis of model simulations are used to demonstrate that SOAEs are a global phenomenon that arises due to the collective action of a distributed region of the cochlea rather than from spontaneous oscillations from individual outer hair cells.
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8

DALLOS, P. "SOME PENDING PROBLEMS IN COCHLEAR MECHANICS." In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812704931_0013.

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ULFENDAHL, M., J. BOUTET DE MONVEL, and A. FRIDBERGER. "VISUALIZING COCHLEAR MECHANICS USING CONFOCAL MICROSCOPY." In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812704931_0040.

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10

Biswas, Amitava. "A Novel Analysis of the Mechanics of Cochlea, the Inner Ear." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-42394.

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Abstract:
The human ear is often regarded as a paragon of mechanical engineering. To understand how the hearing system works, scientists have proposed detailed models of its specific aspects—the transfer of acoustic energy from the atmosphere to the tympanic membrane via the external ear; the coupling of the tympanic membrane to the oval window of the cochlea via ossicles; the resultant fluidic oscillations in the cochlear ducts; the formation of traveling waves in the basilar membrane of the cochlea; the mechanical stimulation of inner hair cells by the basilar membrane; and the consequential transduction of nerve impulses. Scientists have also proposed models to explain the phenomenon of enhancement of the traveling waves in the basilar membrane by synchronized co-contraction in the length of outer hair cells (OHCs). Although it is unrealistic that any OHC would contract in length without expanding in diameter, the models proposed by other analysts have so far incorporated the longitudinal contraction of OHCs only, suggesting that the impact of any diametric expansion of OHCs would be relatively trival. Here we show that the basilar membrane would behave like a Beam-Column system, which may be significantly influenced by the diametric expansion of OHCs.
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