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Journal articles on the topic 'Cockcroft-Gault formula'

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Published: 4 June 2025

Last updated: 14 July 2025

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1

Zanoli, Luca, Giulia Romano, Marcello Romano, et al. "Renal Function and Ultrasound Imaging in Elderly Subjects." Scientific World Journal 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/830649.

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We evaluated in elderly subjects (a) the ability of GFR formulas to discriminate chronic kidney disease (CKD), (b) the correlation between renal morphology and function, and (c) the usefulness of combined r-US and GFR formulas to detect CKD. A total of 72 patients were enrolled (mean age 80 ± 7 years, male sex 44%, serum creatinine 0.98 ± 0.42 mg/dL, and CKD 57%). Cockcroft-Gault showed the highest sensitivity (78%) and specificity (94%) for CKD and was correlated with kidney volume (R=0.68,P<0.001). All formulas failed to provide a reliable estimate of GFR. In multivariate analysis, Cockcr

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2

Chowdhury, Jenat Zareen, Mohammad Masum Alam, and Forhadul Hoque Mollah. "Comparison of CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) formula based eGFR (estimated glomerular filtration rate) with C-G (Cockcroft-Gaul) and MDRD (Modification of Diet in Renal Disease) formula based eGFR in adult Bangladeshi population." Bangabandhu Sheikh Mujib Medical University Journal 14, no. 4 (2022): 152–56. http://dx.doi.org/10.3329/bsmmuj.v14i4.56616.

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Glomerular filtration rate (GFR) is the most important and accurate measure of overall kidney functions both in good health and disease because it is the sum of the filtration rates in each of the functioning nephrons .Different GFR measuring methods have some limitations.The objective of this study was to compare the CKD-EPI formula based eGFR with that of Cock- croft- Gault formula & 4 variable MDRD formula based eGFR.This Cross-sectional analytical study was done in the Department of Biochemistry & Molecular biology, BSMMU September during the period of July 2017 to August 2018. Ser

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Lavrishcheva, Y. V., A. A. Yakovenko, and A. N. Belskykh. "Criteria for assessing renal allograft dysfunction." Bulletin of the Russian Military Medical Academy 22, no. 2 (2020): 16–18. http://dx.doi.org/10.17816/brmma50038.

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The significance of the glomerular filtration rate calculated by the Cockcroft - Gault formula as one of the highly sensitive criteria for assessing renal allograft dysfunction is substantiated. The study demonstrated that in the group of patients with an increased level of daily proteinuria there is a significantly lower level of serum creatine in comparison with the group of patients with a normal level of daily proteinuria. Moreover, in patients with a normal level of daily proteinuria, there are significantly higher values of glomerular filtration rate calculated by the Cockcroft - Gault f

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4

Park, E. Y., and T. Y. Kim. "The original sin of Cockcroft-Gault formula." Nephrology Dialysis Transplantation 25, no. 4 (2010): 1347–50. http://dx.doi.org/10.1093/ndt/gfp702.

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Lavrishcheva, Yu V., and E. S. Kuvardin. "CLINICO-LABORATORY CRITERIA FOR EVALUATING DYSFUNCTION OF KIDNEY ALLOTRASPLAT FOR THE OPTIMIZATION OF IMMUNOSUPRESS SCHEMES IN THE EARLY AND REMOTE PERIODS AFTER KIDNEY TRANSPLANTATION." Translational Medicine 5, no. 6 (2019): 5–9. http://dx.doi.org/10.18705/2311-4495-2018-5-6-.

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Background. A significant role in solving the problem of renal replacement therapy should be played by kidney transplantation, which is now widely regarded as the optimal method for treating end-stage renal failure. An important problem remains the survival of the graft, and therefore it is necessary to find the most optimal method for diagnosing the earliest lesion of the graft.Objective. Examine the possibility of using glomerular filtration rate calculated by the Cockcroft–Gault (C&G) and EPI formulas to assess renal allograft function.Design and methods. 216 patients with functioning r

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Lavrishcheva, Yu V., and E. S. Kuvardin. "CLINICO-LABORATORY CRITERIA FOR EVALUATING DYSFUNCTION OF KIDNEY ALLOTRASPLAT FOR THE OPTIMIZATION OF IMMUNOSUPRESS SCHEMES IN THE EARLY AND REMOTE PERIODS AFTER KIDNEY TRANSPLANTATION." Translational Medicine 5, no. 6 (2019): 5–9. http://dx.doi.org/10.18705/2311-4495-2018-5-6-5-9.

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Background. A significant role in solving the problem of renal replacement therapy should be played by kidney transplantation, which is now widely regarded as the optimal method for treating end-stage renal failure. An important problem remains the survival of the graft, and therefore it is necessary to find the most optimal method for diagnosing the earliest lesion of the graft.Objective. Examine the possibility of using glomerular filtration rate calculated by the Cockcroft–Gault (C&G) and EPI formulas to assess renal allograft function.Design and methods. 216 patients with functioning r

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7

Nevins, Michael, and Michael Bright. "COCKCROFT-GAULT FORMULA FOR DIAGNOSING MODERATE KIDNEY FAILURE." Journal of the American Geriatrics Society 56, no. 4 (2008): 774. http://dx.doi.org/10.1111/j.1532-5415.2008.01634.x.

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8

Helou, Rafik. "Should We Continue to Use the Cockcroft-Gault Formula?" Nephron Clinical Practice 116, no. 3 (2010): c172—c186. http://dx.doi.org/10.1159/000317197.

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9

Syvolap, V. V., and V. A. Lysenko. "Dependence of renal filtration capacity on the phenotype of chronic heart failure, indicators of systolic and diastolic heart function." Pathologia 18, no. 1 (2021): 4–11. http://dx.doi.org/10.14739/2310-1237.2021.1.223742.

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The issue of changes in the filtration capacity of the kidneys depending on the structural-geometric and functional remodeling of the heart in different phenotypes of chronic heart failure, disorders of systolic and diastolic function of the left ventricle remains insufficiently studied. The aim of this work: to investigate the relationship between changes in the filtration capacity of the kidneys in patients with chronic heart failure of ischemic genesis depending on the phenotype, indicators of systolic and diastolic cardiac function. Materials and methods. After an informed consent was sign

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Sokoll, L. J., R. M. Russell, J. A. Sadowski, and F. D. Morrow. "Establishment of creatinine clearance reference values for older women." Clinical Chemistry 40, no. 12 (1994): 2276–81. http://dx.doi.org/10.1093/clinchem/40.12.2276.

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Abstract Age-adjusted reference ranges for creatinine clearance were determined in 279 women, ages 40-95 years, who were housed in a metabolic research unit and consumed a meat-free diet. Creatinine clearance, but not serum creatinine, declined with age by 0.63 mL/min per 1.73 m2 per year. Serum and urine creatinine concentrations, used to calculate clearances, were analyzed by a kinetic Jaffé procedure. In a subset of 100 subjects, fasting serum creatinine values averaged 8.3 +/- 5.2 (SD) mumol/L higher when measured by the kinetic Jaffé procedure than by an enzymatic method (creatinine PAP).

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Djite, Moustapha, Philomène Lopez Sall, Ambroise Wonkam, et al. "Détermination du débit de filtration glomérulaire au cours de la drépanocytose au Sénégal: Schwartz, Cockcroft et Gault, MDRD, CKD-EPI ou JSCCS ?" International Journal of Biological and Chemical Sciences 15, no. 6 (2022): 2283–96. http://dx.doi.org/10.4314/ijbcs.v15i6.4.

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La détermination du Débit de Filtration Glomérulaire (DFG) est importante chez les drépanocytaires du fait qu’ils constituent un groupe de patients chez lesquels des atteintes rénales sont fréquemment décrites notamment l’hyperfiltration glomérulaire. Dès lors, à une époque où les calculateurs en ligne proposent simultanément différentes formules de détermination du DFG, il serait important d’évaluer au sein d’une population noire africaine drépanocytaire l’équivalence entre ces formules qui ont été développées et validées sur des populations caucasiennes et afro-américaines à DFG normal ou di

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12

Filler, Guido, Jennifer Foster, A. M. Y. Acker, Nathalie Lepage, Ayub Akbari, and Jochen H. H. Ehrich. "The Cockcroft-Gault formula should not be used in children." Kidney International 67, no. 6 (2005): 2321–24. http://dx.doi.org/10.1111/j.1523-1755.2005.00336.x.

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13

Tolossa, Wubshet Jote, Tigist Workneh Leulseged, Abdu Adem, et al. "Agreement of glomerular filtration rate estimation equations for chemotherapy dosing in cancer patients at a tertiary referral hospital in Sub-Saharan Africa." PLOS One 20, no. 6 (2025): e0325883. https://doi.org/10.1371/journal.pone.0325883.

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Introduction Narrow therapeutic indices of chemotherapeutic agents necessitate precise dosing to ensure efficacy and minimize nephrotoxicity. Due to the complexity of directly measuring Glomerular filtration rate (GFR), renal dosing is usually based on GFR estimation equations. The Cockcroft-Gault formula remains the most widely used equation in cancer patients, despite the availability of more precise kidney function estimation equations. Therefore, the aim of the study was to assess the agreement between Cr and cystatin-C (CysC) based GFR estimation equations and GFR estimated by Cockcroft-G

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Tapper, Marlene, Donovan A. McGrowder, Lowell Dilworth, and Adedamola Soyibo. "Prospective Comparison of 24-Hour Urine Creatinine Clearance with Estimated Glomerular Filtration Rates in Chronic Renal Disease Patients of African Descent." Medicines 8, no. 9 (2021): 48. http://dx.doi.org/10.3390/medicines8090048.

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Background: The 24-hour (24-h) creatinine clearance (CrCl) is the most common method for measuring GFR in clinical laboratories. However, the limitations of CrCl have resulted in the widespread acceptance of mathematically derived estimated glomerular filtration rate (eGFR) using Cockcroft-Gault (CG), Modification of Diet in Renal Disease (MDRD) and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations in predicting eGFR. The aim of the study was to compare 24-h CrCl with eGFR derived from these formulae and to identify which could be the best alternative. Method: A prospec

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Stehling, Florian, Rainer Büscher, Jörg Grosse-Onnebrink, Peter F. Hoyer, and Uwe Mellies. "Glomerular and Tubular Renal Function after Repeated Once-Daily Tobramycin Courses in Cystic Fibrosis Patients." Pulmonary Medicine 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/2602653.

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Introduction. Antibiotic treatment regimens againstPseudomonas aeruginosalung infection in cystic fibrosis (CF) patients often include aminoglycoside antibiotics that may cause chronic renal failure after repeated courses. Aminoaciduria is an early marker of acute aminoglycoside-induced renal tubular dysfunction. We hypothesized that urinary amino acid reabsorption is decreased after repeated once-daily tobramycin therapies.Methods. In this prospective cross-sectional study creatinine clearance was estimated by the Schwartz and the Cockcroft-Gault formula. Tubular amino acid reabsorption was d

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Shiganov, S. V., V. V. Baev, and A. P. Shulbayev. "The comparative analysis of therapy by «typical practice» and the fixed combination perindopril and indapamide an arterial hypertension with kidney insufficiency." Systemic Hypertension 10, no. 4 (2013): 66–69. http://dx.doi.org/10.26442/sg28992.

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Results of the conducted prospektivny clinical research devoted to a comparative assessment of hypotensive and nefroprotektivny efficiency of the fixed combination perindopril and indapamid in comparison with by «typical practice» treatments of an arterial hypertension with kidney insufficiency on the frequency of achievement and maintenance of level of target arterial pressure, dynamics of a system glomerular filtration of a formula to the Cockcroft-Gault.

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Ruzhylo, Sofiya, Xawery Żukow, Dariya Popovych, et al. "Assessment of the rate of glomerular filtration by a non-invasive method." Journal of Education, Health and Sport 60 (May 21, 2024): 51613. http://dx.doi.org/10.12775/jehs.2024.60.51613.

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Background. Existing methods for assessing glomerular filtration rate (GF) are invasive. Therefore, we set ourselves the goal of evaluating the rate of glomerular filtration by a non-invasive method. Materials and Methods. The object of observations were 10 men aged 37-69 years without clinical diagnosis tested twice with 7-days interval. The rate of glomerular filtration was calculated according to endogenous creatinine clearance and the Cockcroft & Gault formula. Systolic and diastolic blood pressure was measured three times in a row. The state of the autonomic nervous system was assesse

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Ruzhylo, Sofiya, Xawery Żukow, Dariya Popovych, et al. "Assessment of the rate of glomerular filtration by a non-invasive method." Journal of Education, Health and Sport 59 (May 21, 2024): 51613. http://dx.doi.org/10.12775/jehs.2024.68.51613.

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Background. Existing methods for assessing glomerular filtration rate (GF) are invasive. Therefore, we set ourselves the goal of evaluating the rate of glomerular filtration by a non-invasive method. Materials and Methods. The object of observations were 10 men aged 37-69 years without clinical diagnosis tested twice with 7-days interval. The rate of glomerular filtration was calculated according to endogenous creatinine clearance and the Cockcroft & Gault formula. Systolic and diastolic blood pressure was measured three times in a row. The state of the autonomic nervous system was assesse

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Myara, I., F. Lahiani, C. Cosson, A. Duboust, and N. Moatti. "Estimated Creatinine Clearance by the Formula of Gault and Cockcroft in Renal Transplantation." Nephron 51, no. 3 (1989): 426–27. http://dx.doi.org/10.1159/000185340.

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Coyle, J. M., R. Sarkar, B. K. Bhowmick, and R. J. Meara. "Cockcroft and Gault Formula for Estimation of Creatinine Clearance: Should We Adopt it?" Age and Ageing 26, suppl 3 (1997): P19. http://dx.doi.org/10.1093/ageing/26.suppl_3.p19-c.

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21

Lee, Kwang-No, Jong-Il Choi, Yun Gi Kim, et al. "Comparison of Renal Function Estimation Formulae for Dosing Direct Oral Anticoagulants in Patients with Atrial Fibrillation." Journal of Clinical Medicine 8, no. 12 (2019): 2034. http://dx.doi.org/10.3390/jcm8122034.

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The Cockcroft-Gault (CG) formula is recommended to guide clinicians in the choice of the appropriate dosage for direct oral anticoagulants (DOACs). However, the performance of the CG formula varies depending on the patient’s age, weight, and degree of renal function. We aimed to compare the validity of the CG formula with that of Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) formulae for dosing DOACs. A total of 6268 consecutive patients on anticoagulants for atrial fibrillation (AF) were retrospectively investigated. Among underwe

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Hasna, Hasna, Liong Boy Kurniawan, and Fitriani Mangarengi. "Correlation of Serum Creatinine Based on Cockcroft-Gault and CKD-EPI in Diabetes Mellitus." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 31, no. 2 (2025): 167–71. https://doi.org/10.24293/ijcpml.v31i2.2327.

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World Health Organization (WHO) predicts Indonesia's population with Type 2 Diabetes Mellitus (T2DM) will rise from 8.4 million in 2000 to 21.3 million in 2030. The primary cause of disability and death in people with Diabetes Mellitus (DM) is nephropathy. The early stages of diabetic nephropathy are characterized by glomerular hyperfiltration and an increase in the estimated-Glomerular Filtration Rate (eGFR). Other markers of diabetic nephropathy in addition to eGFR are increased creatinine, albuminuria, and proteinuria. The currently developed formulas for eGFR assessment are the Cockcroft-G

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Rigalleau, Vincent, Catherine Lasseur, Caroline Perlemoine, et al. "Cockcroft-Gault formula is biased by body weight in diabetic patients with renal impairment." Metabolism 55, no. 1 (2006): 108–12. http://dx.doi.org/10.1016/j.metabol.2005.07.014.

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Shrewsberry, Timothy W., Ashraf Banoub, Kevin Fleming, Holly Snyder, and James Stehlik. "Spreadsheet Use to Calculate Creatinine Clearance From Serum Creatinine." Journal of ExtraCorporeal Technology 39, no. 4 (2007): 260–62. http://dx.doi.org/10.1051/ject/200739260.

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Spreadsheets may be created to include the Cockcroft-Gault Formula (CGF) for creatinine-based estimation of glomerular filtration rate. Creatinine clearance (CrCl) provides a more accurate method for perioperative risk assessment of renal function than serum creatinine. CrCl may be used to develop guidelines for renal protective management strategies during cardiopulmonary bypass. CGF uses serum creatinine, age, kilogram weight, sex, and “logical test” functions within the spreadsheet to calculate the CrCl. Implementation of spreadsheets has the potential for numerous other calculations and ma

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Ballo, Piercarlo, Tania Chechi, Gaia Spaziani, et al. "Prognostic comparison between creatinine-based glomerular filtration rate formulas for the prediction of 10-year outcome in patients with non-ST elevation acute coronary syndrome treated by percutaneous coronary intervention." European Heart Journal: Acute Cardiovascular Care 7, no. 8 (2017): 689–702. http://dx.doi.org/10.1177/2048872617697452.

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Background: Estimated glomerular filtration rate (eGFR) is a predictor of outcome among patients with non-ST-elevation acute coronary syndrome (NSTE-ACS), but which estimation formula provides the best long-term risk stratification in this setting is still unclear. We compared the prognostic performance of four creatinine-based formulas for the prediction of 10-year outcome in a NSTE-ACS population treated by percutaneous coronary intervention. Methods: In 222 NSTE-ACS patients submitted to percutaneous coronary intervention, eGFR was calculated using four formulas: Cockcroft–Gault, re-express

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Grueso Cuesta, Cristina, Jaime E. Poquet Jornet, Juan M. Gasent Blesa, Antonio Valdivia Perez, Francisco J. Carrera Hueso, and Lucrecia Moreno Royo. "Toxicity and effectiveness of carboplatin in obese or overweight patients." Journal of Oncology Pharmacy Practice 25, no. 6 (2018): 1328–35. http://dx.doi.org/10.1177/1078155218790339.

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Objective To evaluate the efficiency and toxicity of carboplatin using actual body weight in obese/overweight patients using the Calvert formula with Cockcroft–Gault for CrCl estimation. Methods We evaluated the association of BMI in regards to efficiency and toxicity in a retrospective cohort study of patients who started treatment with carboplatin between 2012 and 2013. Cohorts included obese/overweight patients and normal-weight patients. Efficiency was measured by overall survival, progression-free survival and response rate. Toxicity was measured by the proportion of dose reductions and d

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Parvin, Mimi, Md Aminul Haque Khan, Muhammad Saiedullah, Muhammad Rezwanur Rahman, Md Saiful Islam, and Lubna Naznin. "Comparison of CCR, Cockcroft-Gault and Mdrd Formula for the Estimation of Glomerular Filtration Rate." Journal of Bangladesh College of Physicians and Surgeons 33, no. 4 (2016): 207–12. http://dx.doi.org/10.3329/jbcps.v33i4.28141.

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Many organizations recommend the use of equations that provide a rapid method of assessing glomerular filtration rate (GFR) to facilitate the detection, evaluation, and management of chronic kidney diseases. Indeed, many clinical laboratories already report estimated GFR (eGFR) values whenever the serum creatinine level is measured. To compare the predictive equations for the measurement of GFR in Bangladeshi population, we measured GFR by creatinine clearance rate (CCR) and also estimated it by Modification of Diet in Renal Disease (MDRD) 4 variables equation and Cockcroft and Gault (C-G) for

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Lees, K., H. Taylor, R. Shah, and R. Burcombe. "Retrospective analysis of EDTA-GFR versus Cockcroft-Gault formula in lung patients receiving carboplatin chemotherapy." Lung Cancer 63 (January 2009): S7. http://dx.doi.org/10.1016/s0169-5002(09)70021-2.

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Lamb, Edmund J., Charles RV Tomson, and Paul J. Roderick. "Estimating kidney function in adults using formulae." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 42, no. 5 (2005): 321–45. http://dx.doi.org/10.1258/0004563054889936.

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With increasing emphasis on the earlier detection and management of chronic kidney disease (CKD), estimation of the glomerular filtration rate (GFR) has assumed greater importance. It is accepted that use of serum creatinine concentration alone as a marker of kidney function is inadequate; in particular, it has a poor sensitivity for detecting CKD. International recommendations favour the reporting of creatinine-based estimates of GFR using formulae which also take into account age, gender and other variables that affect the relationship between serum creatinine and GFR: in particular, the fou

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Syed Akhter Muhammad, Muhammad Usman, Muhammad Naseer, Muhammad Azam, Syed Mohkumuddin, and Abdul Malik. "Update on Assessment of Estimated Glomerular Filtration Rate in Patients with Cirrhosis." Indus Journal of Bioscience Research 3, no. 5 (2025): 727–29. https://doi.org/10.70749/ijbr.v3i5.1511.

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Background: cirrhosis causes muscle loss and changes in creatinine levels, it is difficult to assess renal function in these patients. Often, creatinine-based processes calculate GFR too high which causes renal diseases to be diagnosed late and the illness to be undertreated. Objectives: To study which eGFR equation works best in cirrhotic patients and can most reliably be used in assessing and detecting early kidney impairment. Study Design: A Cross-Sectional Study. Place and Duration of study: From May 2024 to December 2024 Nephrology & Gastroenterology Department, Sandeman Provincial Ho

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Laroche, Marie-Laure, Jean-Pierre Charmes, Aline Marcheix, François Bouthier, and Louis Merle. "Estimation of Glomerular Filtration Rate in the Elderly: Cockcroft-Gault Formula versus Modification of Diet in Renal Disease Formula." Pharmacotherapy 26, no. 7 (2006): 1041–46. http://dx.doi.org/10.1592/phco.26.7.1041.

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Ferreira-Filho, Sebastião Rodrigues, Camila Caetano Cardoso, Luiz Augusto Vieira de Castro, Ricardo Mendes Oliveira, and Renata Rodrigues Sá. "Comparison of Measured Creatinine Clearance and Clearances Estimated by Cockcroft-Gault and MDRD Formulas in Patients with a Single Kidney." International Journal of Nephrology 2011 (2011): 1–4. http://dx.doi.org/10.4061/2011/626178.

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There are doubts about whether the values obtained from the Cockroft-Gault (ClCG) and Modification of Diet in Renal Disease (GFRMDRD) formulas are comparable to the more traditional formula used to obtain the creatinine clearance from a 24-hour urine collection (ClCrm), particularly in patients with only one kidney. The present study aimed to compare these formulas in individuals with one remaining kidney after previous nephrectomy (Nx) and to verify which estimated formula correlates more closely with ClCrm. Thirty-six patients who had undergone Nx had their renal filtration analyzed with ClC

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Ogarkov, M. Yu, E. S. Filimonov, T. A. Mulerova, and A. A. Kuzmina. "Functional state of kidneys and arterial hypertension among indigenous and nonindigenous residents of Mountain Shoria." Systemic Hypertension 12, no. 1 (2015): 43–46. http://dx.doi.org/10.26442/sg29090.

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Goal: to investigate the interrelation between arterial hypertension and functional state of kidneys among indigenous and nonindigenous Mountain Shoria residents.Material and methods. 370 Mountain Shoria residents (consisting of 113 men and 257 women) were examined. All examinees were 51,07±1,46 and 52,93±0,96 years old on average. The level of blood creatinine was determined by all examinees. Its clearance was calculated according to the Cockcroft-Gault formula in order to determine the glomerular filtration rate. The calculated values were matched with the average square of the body surface

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Casal, Morgan A., Thomas D. Nolin, and Jan H. Beumer. "Estimation of Kidney Function in Oncology." Clinical Journal of the American Society of Nephrology 14, no. 4 (2019): 587–95. http://dx.doi.org/10.2215/cjn.11721018.

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Estimation of kidney function in patients with cancer directly affects drug dosing, agent selection, and eligibility for clinical trials of novel agents. Overestimation of kidney function may lead to overdosing or inappropriate agent selection and corresponding toxicity. Conversely, underestimation of kidney function may lead to underdosing or inappropriate agent exclusion and subsequent therapeutic failure. It would seem obvious that the most accurate estimates of kidney function should be used to reduce variability in decision making and ultimately, the therapeutic outcomes of toxicity and c

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Šečić, D., A. Turohan, E. Begić, et al. "Serum creatinine vs corrected cockcroft-gault formula according to Poggio reference values in patients with arterial hypertension." Atherosclerosis 331 (August 2021): e234-e235. http://dx.doi.org/10.1016/j.atherosclerosis.2021.06.721.

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Rigalleau, V., C. Lasseur, C. Perlemoine, et al. "A simplified Cockcroft-Gault formula to improve the prediction of the glomerular filtration rate in diabetic patients." Diabetes & Metabolism 32, no. 1 (2006): 56–62. http://dx.doi.org/10.1016/s1262-3636(07)70247-1.

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Burkhardt, H., G. Bojarsky, N. Gretz, and R. Gladisch. "Creatinine Clearance, Cockcroft-Gault Formula and Cystatin C: Estimators of True Glomerular Filtration Rate in the Elderly?" Gerontology 48, no. 3 (2002): 140–46. http://dx.doi.org/10.1159/000052832.

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Vervoort, Gerald, Jacqueline M. T. Klein Gunnewiek, Hans L. Willems, and Jack F. M. Wetzels. "Effect of creatinine assay standardization on the performance of Cockcroft–Gault and MDRD formula in predicting GFR." Nephrology Dialysis Transplantation 21, no. 10 (2006): 2998–99. http://dx.doi.org/10.1093/ndt/gfl276.

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Kemperman, Frits A., Janto Surachno, Raymond T. Krediet, and Lambertus Arisz. "Cimetidine improves prediction of the glomerular filtration rate by the cockcroft-gault formula in renal transplant recipients." Transplantation 73, no. 5 (2002): 770–74. http://dx.doi.org/10.1097/00007890-200203150-00020.

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Stöhr, Wolfgang, A. Sarah Walker, Paula Munderi, et al. "Estimating Glomerular Filtration Rate in HIV-Infected Adults in Africa: Comparison of Cockcroft–Gault and Modification of Diet in Renal Disease Formulae." Antiviral Therapy 13, no. 6 (2008): 761–70. http://dx.doi.org/10.1177/135965350801300613.

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Background Cockcroft–Gault (CG) and Modification of Diet in Renal Disease (MDRD) formulae are recommended for glomerular filtration rate (GFR) estimation, but neither has been validated or directly compared longitudinally in HIV-infected patients or in Africa. Methods We investigated differences between formulae in baseline GFR, GFR changes and incidence of impaired GFR after initiation of antiretroviral therapy (ART) in 3,316 HIV-infected adults in Africa, considering sex, age, body mass index and baseline laboratory parameters as predictors. Results Participants were 65% women, median age 36

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Cai, FengQing, Li Ren, Hong Liu, et al. "The Relationship between the Level of Serum Creatinine, Modified Diet and Renal Disease Formula, Cockcroft–Gault Formula, and Renal Tubulointerstitial Lesion." Renal Failure 34, no. 3 (2012): 334–37. http://dx.doi.org/10.3109/0886022x.2011.647304.

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Grubb, A., J. Björk, V. Lindström, G. Sterner, P. Bondesson, and U. Nyman. "A cystatin C‐based formula without anthropometric variables estimates glomerular filtration rate better than creatinine clearance using the Cockcroft‐Gault formula." Scandinavian Journal of Clinical and Laboratory Investigation 65, no. 2 (2005): 153–62. http://dx.doi.org/10.1080/00365510510013596.

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Bevc, Sebastjan, Radovan Hojs, Robert Ekart, Matej Završnik, Maksimiljan Gorenjak, and Ludvik Puklavec. "Simple Cystatin C Formula for Estimation of Glomerular Filtration Rate in Overweight Patients with Diabetes Mellitus Type 2 and Chronic Kidney Disease." Experimental Diabetes Research 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/179849.

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In clinical practice the glomerular filtration rate (GFR) is estimated from serum creatinine-based equations like the Cockcroft-Gault formula (C&G) and Modification of Diet in Renal Disease formula (MDRD). Recently, serum cystatin C-based equations, the newer creatinine formula (The Chronic Kidney Disease Epidemiology Collaboration formula (CKD-EPI)), and equation that use both serum creatinine and cystatin C (CKD-EPI creatinine & cystatin formula) were proposed as new GFR markers. Present study compares serum creatinine-based equations, combined (including both serum creatinine and cy

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Januškevičiūtė, Elija, Vaidas Vicka, Justina Krauklytė, et al. "Acute Kidney Injury in Cardiac Surgery Patients: Role of Glomerular Filtration Rate and Fat-Free Mass." Acta medica Lituanica 28, no. 1 (2021): 22. http://dx.doi.org/10.15388/amed.2021.28.1.22.

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Background: eGFR (estimated glomerular filtration rate) formulas may be inaccurate in overweight cardiac surgery patients, overestimating the kidney reserve. The aim of this study was to modify the eGFR formulas and to determine whether the modified eGFR is a more accurate predictor of acute kidney injury (AKI).Materials and methods: The patients were assigned into 4 BMI groups as follows: normal weight (18.5–25 kg/m2), pre-obesity (25–30 kg/m2), class I obese (30–35 kg/m2), class II and III obese (≥35 kg/m2). Cockcroft–Gault (CG) eGFR formula was modified by using the fat-free mass (FFM) deri

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Quadri, K. H. M., J. Bernardini, A. Greenberg, S. Laifer, A. Syed, and J. L. Holley. "Assessment of Renal Function During Pregnancy Using a Random Urine Protein to Creatinine Ratio and Cockcroft-Gault Formula." American Journal of Kidney Diseases 24, no. 3 (1994): 416–20. http://dx.doi.org/10.1016/s0272-6386(12)80897-3.

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Rotmans, Joris I., Wijnanda J. Frenkel, Raymond T. Krediet, and Sophia E. J. A. De Rooij. "THE PREDICTIVE VALUE OF THE COCKCROFT-GAULT FORMULA AND THE MODIFICATION OF DIET IN RENAL DISEASE FORMULA FOR MORTALITY IN ELDERLY PEOPLE." Journal of the American Geriatrics Society 57, no. 5 (2009): 946–48. http://dx.doi.org/10.1111/j.1532-5415.2009.02251.x.

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Weidling, H., H. P. Breuel, H. J. Biersack, and M. J. Reinhardt. "Detection of impaired renal function." Nuklearmedizin 43, no. 06 (2004): 203–9. http://dx.doi.org/10.1055/s-0038-1623917.

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Summary Aim: Renal function is usually determined by means of creatinine-clearance, and of serum Cystatin C, the latter with increasing frequency. The present study analyses, whether the diagnostic accuracy of 99mTc-MAG3 clearance is comparable to that of these modern serologic methods. Patienten, Methods: 71 consecutive adult Caucasian patients (42 female, 29 male; age 50 ± 16 yrs., range 20 – 83) who were referred to a nuclear medicine department for determination of bilateral renal function with 99mTc-MAG3 were included. Following sufficient hydration, 10 ml of blood were taken for determin

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Wu, Xiaoyun, Feng Qiu, Xianglan Jin, Qiang Liu, Jian Zhou, and Xia Duan. "Evaluation of Four eGFR Calculating Formulae in Predicting Postoperative Acute Kidney Injury in Adult Patients Undergoing Open-Heart Surgery with Cardiopulmonary Bypass." Contrast Media & Molecular Imaging 2022 (July 13, 2022): 1–6. http://dx.doi.org/10.1155/2022/6929758.

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Objective. There are four widely-used formulae to calculate the perioperative glomerular filtration rate (GFR) of patients undergoing cardiac surgery. We assessed the predictive values of these formulae in the occurrence of postoperative acute kidney injury (AKI). Methods. Patients who underwent open-heart valvular surgery with cardiopulmonary bypass from January 2015 to October 2017 were enrolled in this retrospective study. Demographic data and perioperative serum creatinine levels were collected. The estimated GFR (eGFR) was calculated using four formulae: Cockcroft Gault (CG), body surface

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Cemin, Roberto, Luisa Foco, Carmine Zoccali, and Raffaele De Caterina. "Should We Continue Assessing Glomerular Filtration Rate with the Cockroft–Gault Formula in NOAC-Treated Patients? The Magnitude of the Problem." Journal of Clinical Medicine 9, no. 6 (2020): 1893. http://dx.doi.org/10.3390/jcm9061893.

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Despite the proven superiority of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) over the Cockcroft–Gault (CG) formula, current guidelines recommend the latter to assess renal function in patients treated with non-vitamin K antagonist oral anticoagulants (NOACs). To assess the relationship between the CG and the recommended CKD-EPI formulas, in a cohort of atrial fibrillation (AF) patients treated with NOACs, and the misclassifications introduced by the CG formula for renal function levels, we estimated renal function with three equations: CG, CKD-EPI with body surface adjustm

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Kim, Hyun-Ki, and Tae-Dong Jeong. "Clinical Relevance of a Vancomycin 24 h Area under the Concentration—Time Curve Values Using Different Renal Function Equations in Bayesian Dosing Software." Journal of Personalized Medicine 13, no. 1 (2023): 120. http://dx.doi.org/10.3390/jpm13010120.

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With the updated 2020 vancomycin therapeutic drug monitoring (TDM) guidelines suggesting a ratio of area under the curve over 24 h to a minimum inhibitory concentration (AUC24/MIC) as a target from the Infectious Diseases Society of America, an accurate estimation of AUC24 has become more critical. We aim to compare the AUC24 using Bayesian dosing software according to various estimated glomerular filtration rate (eGFR) equations in order to analyze the clinical impact of eGFR in vancomycin TDM. We reviewed the TDM dataset of 214 adult patients and analyzed the AUC24 values from various renal

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