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Journal articles on the topic 'Cog Tool'

Author: Grafiati

Published: 4 June 2021

Last updated: 17 February 2022

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1

LoGiudice, D., K. Smith, J. Thomas, et al. "Kimberley Indigenous Cognitive Assessment tool (KICA): development of a cognitive assessment tool for older indigenous Australians." International Psychogeriatrics 18, no. 2 (2006): 269–80. http://dx.doi.org/10.1017/s1041610205002681.

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Background: Indigenous Australians have a unique cultural heritage dating back many thousands of years. Unfortunately, there is no validated tool to assess cognition in older indigenous Australians. This study was designed to address this deficiency. The Kimberley Indigenous Cognitive Assessment (KICA) was developed with Indigenous health and aged care organizations, and comprises cognitive, informant and functional sections. The psychometric properties of the cognitive assessment section (KICA-Cog) are described in this paper.Methods: The KICA-Cog was tested in 70 indigenous subjects, of vary

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Barczak, Anna, and Beata Hintze. "Mini-Cog as ascreening tool for dementia." Aktualności Neurologiczne 19, no. 3 (2019): 141–44. http://dx.doi.org/10.15557/an.2019.0019.

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3

Dyer, Suzanne M., Kate Laver, Margeret Friel, Craig Whitehead, and Maria Crotty. "The diagnostic accuracy of the Kimberley Indigenous Cognitive Assessment (KICA) tool: a systematic review." Australasian Psychiatry 25, no. 3 (2017): 282–87. http://dx.doi.org/10.1177/1039856216684735.

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Objectives: The objective of this study was to conduct a systematic review of evidence for the accuracy of the Kimberley Indigenous Cognitive Assessment (KICA) tool in supporting the diagnosis of dementia in Indigenous Australian populations. Methods: Cross-sectional diagnostic accuracy studies of the KICA with an appropriate reference standard published to November 2015 were included. Comparison to an alternative cognitive assessment tool was required in non-remote populations. Case control analyses were excluded. Results: Four studies were included: one of the KICA-Cog and KICA-Carer, one of

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Smith, K., L. Flicker, D. Atkinson, et al. "The KICA Carer: informant information to enhance the Kimberley Indigenous Cognitive Assessment." International Psychogeriatrics 28, no. 1 (2015): 101–7. http://dx.doi.org/10.1017/s1041610215001283.

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ABSTRACTBackground:A quality dementia-screening tool is required for older remote Aboriginal Australians who have high rates of dementia and limited access to appropriate medical equipment and clinicians. The Kimberley Indigenous Cognitive Assessment (KICA Cog) is a valid cognitive test for dementia in Aboriginal and Torres Strait Islander peoples. The KICA cognitive informant questionnaire (KICA Carer) had yet to be analyzed to determine validity alone or in combination with the KICA Cog.Methods:The KICA Carer was completed by nominated informants of 349 remote-living Aboriginal Australians i

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Adhikari, Shambhu P., Rubee Dev, and Soo Borson. "Modifying the Mini-Cog to Screen for Cognitive Impairment in Nonliterate Individuals." International Journal of Alzheimer's Disease 2021 (August 16, 2021): 1–6. http://dx.doi.org/10.1155/2021/5510093.

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Objectives. The Mini-Cog, a rapid, valid, and reliable screening tool for cognitive impairment, consists of 3-word recall and an executive clock drawing test (CDT). However, CDT requires at least basic literacy and cultural exposure to analog clocks, conditions not met in many population groups around the world. We developed a modification of the Mini-Cog (MMC) for use with nonliterate and literate individuals. Methods. Participants were adults (≥60 years) with no neurological diagnosis, with known cognitive impairment due to stroke, Parkinsonism, traumatic brain injury, or Alzheimer’s disease

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Peña-Casanova, Jordi. "Alzheimer's Disease Assessment Scale–Cognitive in Clinical Practice." International Psychogeriatrics 9, S1 (1997): 105–14. http://dx.doi.org/10.1017/s1041610297004778.

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The goal of this article is (a) to review a series of measurement standards for group and individual-patient applications of cognitive tests for Alzheimer's disease (AD); and (b) to review the literature and to use specific data from the NORMACODEM (a project of standardization of cognitive and functional tools for AD) to evaluate the measurement standards of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog). Seven measurement standards for group and individual patient use were evaluated: practicality, extent of measurement, depth of measurement, cross-sectional precision, longitud

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Клепиков, Виктор, Viktor Klyepikov, Александр Черепахин, and Alyeksandr CHyeryepakhin. "Peculiarities in easy spur cog-wheel shaving." Science intensive technologies in mechanical engineering 2, no. 6 (2017): 21–25. http://dx.doi.org/10.12737/article_592d14ddcb2a19.76456116.

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A procedure for the definition of female shaver geometrics on the basis of the computation for relative motion velocities of a tool and a blank is offered. On the basis of the theory for the vector direction computation of a relative velocity on a shaver there are developed designs of shavers with sloping and upright chip grooves. Options for chip groove locations for different conditions of shaving are considered.

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Galperin, Michael Y., David M. Kristensen, Kira S. Makarova, Yuri I. Wolf, and Eugene V. Koonin. "Microbial genome analysis: the COG approach." Briefings in Bioinformatics 20, no. 4 (2017): 1063–70. http://dx.doi.org/10.1093/bib/bbx117.

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Abstract For the past 20 years, the Clusters of Orthologous Genes (COG) database had been a popular tool for microbial genome annotation and comparative genomics. Initially created for the purpose of evolutionary classification of protein families, the COG have been used, apart from straightforward functional annotation of sequenced genomes, for such tasks as (i) unification of genome annotation in groups of related organisms; (ii) identification of missing and/or undetected genes in complete microbial genomes; (iii) analysis of genomic neighborhoods, in many cases allowing prediction of novel

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Setter, Stephen M., Joshua J. Neumiller, Melanie Johnson, Soo Borson, and James M. Scanlan. "The Mini-Cog: A Rapid Dementia Screening Tool Suitable for Pharmacists' Use." Consultant Pharmacist 22, no. 10 (2007): 855–61. http://dx.doi.org/10.4140/tcp.n.2007.855.

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Dorajoo, Sreemanee Raaj, Terence NG, Jung-Woo Chae, et al. "A web-based tool to predict chemotherapy-associated cognitive impairment during survivorship." Journal of Clinical Oncology 35, no. 15_suppl (2017): e21609-e21609. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e21609.

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e21609 Background: Chemotherapy-associated cognitive impairment (CACI) experienced during survivorship can dramatically impair quality of life, particularly among patients receiving treatment with curative intent. We construct a web-based tool to predict the risk of self-perceived CACI at 15 months post-chemotherapy initiation among early stage breast cancer patients, to facilitate screening and early intervention. Methods: We recruited patients receiving chemotherapy for early-stage breast cancer between 2011 and 2014. Subjective cognitive function was assessed using FACT-Cog before, during a

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Hobden, Breanne, Jamie Bryant, Megan Freund, Matthew Clapham, and Rob Sanson-Fisher. "Screening for Cognitive Impairment among Community-Dwelling Older Adults: A Comparison of 2 Screening Instruments." Journal of Primary Care & Community Health 12 (January 2021): 215013272110292. http://dx.doi.org/10.1177/21501327211029231.

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Introduction Community aged care services provide support to older adults living in their own homes. Cognitive impairment may increase the complexity of the support required. There is a need to ensure suitable brief screening tools are available to community aged care providers to assess possible cognitive impairment. This study aimed to examine the agreement between 2 validated cognitive impairment screening tools, the Mini-Cog, and Abbreviated Mental Test Score (AMTS), and the perceptions the individuals case manager of Case Manager’s. Methods A cross-sectional survey study was undertaken wi

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Beeldman, Emma, Rosanne Govaarts, Marianne de Visser, et al. "Screening for cognition in amyotrophic lateral sclerosis: test characteristics of a new screen." Journal of Neurology 268, no. 7 (2021): 2533–40. http://dx.doi.org/10.1007/s00415-021-10423-x.

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AbstractCognitive and behavioural impairment in amyotrophic lateral sclerosis (ALS) negatively influences the quality of life and survival, and, therefore, screening for these impairments is recommended. We developed a cognitive screening tool, the amyotrophic lateral sclerosis–frontotemporal dementia–cognitive screen (ALS–FTD–Cog) and aimed to validate it in patients with ALS. During the current study, the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) was published and we, therefore, decided to compare these two cognitive screening methods. The ALS–FTD–Cog was administered to 72 patie

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Harasani, Klejda, Delina Xhafaj, Adrisa Lekaj, Livia Veshi, and Maria del Carmen Olvera-Porcel. "Screening for mild cognitive impairment among older Albanian patients by clinical pharmacists." International Journal of Pharmacy Practice 29, no. 2 (2021): 189–91. http://dx.doi.org/10.1093/ijpp/riab001.

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Abstract Objectives To assess the prevalence of mild cognitive impairment (MCI) and its correlated factors among elderly Albanian patients using different screening tools applied by clinical pharmacists. Methods Patients aged 60 years old or more from two primary care centers located in two Albanian cities were included in the study. Two clinical pharmacists applied the MoCA/MoCA B (Montreal Cognitive Assessment/Basic) and the Mini-Cog in Albanian. A predictive multivariate logistic regression analysis and Kappa statistic were conducted. Key findings The prevalence of MCI using MoCA/MoCA B and

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Jović, Ozren, Dario Omanović, Marina Zelić, and Ivanka Pižeta. "Center of Gravity (COG) Method as a Tool in Processing of Voltammetric Signals." Electroanalysis 27, no. 10 (2015): 2347–56. http://dx.doi.org/10.1002/elan.201500065.

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Thein, M. S., I. S. Browner, C. Klein, M. Binner, and G. R. Shapiro. "Mini-Cog: A brief screening tool for cognitive impairment in older cancer patients." Journal of Clinical Oncology 28, no. 15_suppl (2010): 9064. http://dx.doi.org/10.1200/jco.2010.28.15_suppl.9064.

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Маликов, Андрей, Andrey Malikov, Андрей Сидоркин, Andrey Sidorkin, Станислав Рахметов, and Stanislav Rakhmetov. "Definition of parametric correlation mechanism of shaver-roller diameter with diameter of cylindrical wheel with circular tooth worked by it." Science intensive technologies in mechanical engineering 2018, no. 9 (2018): 39–45. http://dx.doi.org/10.30987/article_5b71326dab0078.99480322.

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A description of the algorithm for computation and synthesis of a shaver-roller machine engagement with a cylindrical cog-wheel with circular teeth (CCCT) for the definition of a tool rational diameter with respect to the diameter of the wheel worked by it is shown.

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Milian, Monika, Anna-Maria Leiherr, Guido Straten, Stephan Müller, Thomas Leyhe, and Gerhard W. Eschweiler. "The Mini-Cog, Clock Drawing Test, and the Mini-Mental State Examination in a German Memory Clinic: specificity of separation dementia from depression." International Psychogeriatrics 25, no. 1 (2012): 96–104. http://dx.doi.org/10.1017/s104161021200141x.

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ABSTRACTBackground: The aim of this study was to assess the specificities of the Mini-Cog, the Clock Drawing Test (CDT), and the Mini-Mental State Examination (MMSE) against depression and healthy controls in a German Memory Clinic. Furthermore, we analyzed the specificities of all three screening instruments in dependence of actual depression severity.Methods: Data from 142 depressed elderly, 438 dementia patients, and 64 healthy controls were retrospectively analyzed. The CDT and an extraction of the three-item recall of the MMSE were used to constitute the Mini-Cog algorithm. Depression sev

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Mittal, Nupur, Anil George, Lizette Leanos, and Paul Kent. "Children’s Oncology Group (COG) clinical trials as exemplars of pragmatism in clinical research." Journal of Clinical Oncology 35, no. 15_suppl (2017): e18188-e18188. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e18188.

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e18188 Background: In 2016, President Obama announced the “Moonshot Cancer Initiative” to advance cancer research. One of the key components of this initiative is promoting enrollment in pragmatic clinical trials and data sharing. As described in 2009 by Thorpe et al, using the 9-domian PRECIS-2 tool, a ‘pragmatic’ trial, as opposed to an ‘explanatory’ trial used to confirm a physiologic hypothesis, is one in which the intervention can be immediately applied into real-world clinical practice (J of Clin Epi:2009). In the US, 60%-90% children are enrolled on COG research trials. State-of-the-art

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Limpawattana, Panita, and Manchumad Manjavong. "The Mini-Cog, Clock Drawing Test, and Three-Item Recall Test: Rapid Cognitive Screening Tools with Comparable Performance in Detecting Mild NCD in Older Patients." Geriatrics 6, no. 3 (2021): 91. http://dx.doi.org/10.3390/geriatrics6030091.

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Background: Early mild neurocognitive disorder (mild NCD) detection can allow for appropriate planning and delay disease progression. There have been few studies examining validated mild NCD detection tools. One such tool that may be of use is the Mini-Cog, which consists of the clock drawing test (CDT) and three-item recall. Methods: This study aimed to compare the diagnostic properties of the Mini-Cog, the CDT alone, and the three-item recall test alone in mild NCD detection according to DSM-5 criteria. The participants were older patients attending the medicine outpatient clinic. Area under

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Kirk, Andrew. "Target Symptoms and Outcome Measures: Cognition." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 34, S1 (2007): S42—S46. http://dx.doi.org/10.1017/s0317167100005552.

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The Cognitive section of the Alzheimer's Disease Assessment Scale (ADAS-Cog) remains the most widely used cognitive measure in dementia trials although it does not assess attention, executive function, or agnosia. Designed for use in Alzheimer's disease (AD), it may not be ideal in assessing patients with other diagnoses. The ADAS-Cog differentiates between AD patients, patients with Mild Cognitive Impairment, and normal controls. It has been used in trials of drugs for vascular and mixed dementia and dementia with Lewy bodies. It is not clear that the ADAS-Cog is adequate for assessing cognit

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Repak, Tomas. "SEISMICALY BALLANCED MACHINE TOOL – MODEL AND SIMULATION OF COG MOVEMENT ABSOLUTISATION OF „FLOATING“ AXIS." MM Science Journal 2011, no. 04 (2011): 282–84. http://dx.doi.org/10.17973/mmsj.2011_12_201113.

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Andersen, Birgitte B., Jette Stokholm, Steen Hasselbalch, Jytte Dock, and Gunhild Waldemar. "P1-047 The ADAS-cog as a routine diagnostic tool in a memory clinic." Neurobiology of Aging 25 (July 2004): S107—S108. http://dx.doi.org/10.1016/s0197-4580(04)80361-0.

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Tatusov, R. L. "The COG database: a tool for genome-scale analysis of protein functions and evolution." Nucleic Acids Research 28, no. 1 (2000): 33–36. http://dx.doi.org/10.1093/nar/28.1.33.

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Ribeiro Filho, Sergio Telles, and Roberto Alves Lourenço. "The performance of the Mini-Cog in a sample of low educational level elderly." Dementia & Neuropsychologia 3, no. 2 (2009): 81–87. http://dx.doi.org/10.1590/s1980-57642009dn30200003.

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Abstract Objectives: To study the criterion validity of the Mini-Cog in low educational level elderly. Design: Cross-sectional and validation design. Setting: Policlínica Piquet Carneiro, an outpatient unit of Rio de Janeiro State University Hospital, in Brazil. Participants: A convenient sample consisting of 306 individuals, 65 yrs or older, selected from April 8th to July 15th, 2002. Methods: All participants underwent comprehensive geriatric evaluations which included the Mini-Mental State Examination (MMSE) and the cognitive part of the Cambridge Examination for Mental Disorders of the Eld

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Geeraerts, Dirk. "The sociosemiotic commitment." Cognitive Linguistics 27, no. 4 (2016): 527–42. http://dx.doi.org/10.1515/cog-2016-0058.

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AbstractCognitive Linguistics should complement the Cognitive Commitment with a Sociosemiotic Commitment: a commitment to make one’s account of human language accord with the status of language as a social semiotic, i. e., as an intersubjective, historically and socially variable tool, and to base that account on a methodology that likewise transcends the individual. By looking at defining features of Cognitive Linguistics (its cognitive orientation, and its usage-based character), it is argued that the relevance of the Sociosemiotic Commitment derives from the very essence of Cognitive Lingui

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Faust-Socher, Achinoam, Sarah Duff-Canning, Arthur Grabovsky, et al. "Responsiveness to Change of the Montreal Cognitive Assessment, Mini-Mental State Examination, and SCOPA-Cog in Non-Demented Patients with Parkinson’s Disease." Dementia and Geriatric Cognitive Disorders 47, no. 4-6 (2019): 187–97. http://dx.doi.org/10.1159/000496454.

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Background: Clinical monitoring of patients with Parkinson’s disease (PD) for cognitive decline is an important element of care. The Montreal Cognitive Assessment (MoCA) has been proposed to be a sensitive tool for assessing cognitive impairment in PD. The aim of our study was to compare the responsiveness of the MoCA to decline in cognition to the responsiveness of the Mini Mental State Examination (MMSE) and the Scales for Outcomes of Parkinson’s disease-cognition (SCOPA-Cog). Methods: PD patients without dementia were enrolled at 6 North American movement disorders centers between 2008 and

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DeVries, Michael J., and Sallie E. Gordon. "Cog-C: A Tool for Estimating Cognitive Complexity and the Need for Cognitive Task Analysis." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 38, no. 15 (1994): 943. http://dx.doi.org/10.1177/154193129403801504.

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Task analysis is a methodology used during many different phases of system development. However, because many tasks involve complex cognitive processing, there is an increasing need for designers to perform cognitive task analysis. It is generally agreed that cognitive task analysis tends to be costly in terms of time and effort, and many designers ask how they would know when cognitive task analysis should be performed. This demonstration features a computer-based decision aid, Cog-C, to help designers answer this question. The software tool is based on the assumption that cognitive complexit

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Glebkin, Vladimir. "Is conceptual blending the key to the mystery of human evolution and cognition?" Cognitive Linguistics 26, no. 1 (2015): 95–111. http://dx.doi.org/10.1515/cog-2014-0067.

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AbstractThis study addresses conceptual blending theory, as originated by Fauconnier and Turner, focusing on their view of the development of double-scope blending as the cause for the origin of language and forms of culture. The author raises certain criticisms of the theory's underpinnings and methodology. In particular, he points to a lack of cultural-historical analysis and a gap between some of the predictions of conceptual blending theory and the data of real-time experiments. It is shown that a view of blending as an important tool to adapt knowledge to the experience of people is more

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Клепиков, Виктор, Viktor Klyepikov, Александр Черепахин, and Alyeksandr CHyeryepakhin. "Optimization of spline hole broach processes and grinding of cylindrical surfaces in hardened cog-wheels." Science intensive technologies in mechanical engineering 1, no. 8 (2016): 32–36. http://dx.doi.org/10.12737/20813.

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One of the factors affecting considerably gear cutting accuracy consists in technological basis quality. The largest influence upon treatment accuracy of a reference hole have broach wear and errors in hole grinding. In the paper there are shown the investigation results of technological parameter effect upon broach stability and accuracy in broach treatment and grinding of a reference splined hole. The developed model of a process and a tool test allowed defining optimum parameters from the point of view of the treatment accuracy, surface layer parameters and life of a tool and cutting modes.

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Yuanyushkin, A. S., D. A. Rychkov, and D. V. Lobanov. "Surface Quality of the Fiberglass Composite Material after Milling." Applied Mechanics and Materials 682 (October 2014): 183–87. http://dx.doi.org/10.4028/www.scientific.net/amm.682.183.

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One of the prevalent ways of machining is milling, however to obtain the high fiberglass composite surface quality is difficult because of its layered structure, high strength and low thermal conductivity characteristics. This leads to the need for milling technology which provides high-quality surface. Our experiments for milling of the fiberglass composite show that the surface roughness, as one of the quality criteria, to a large depends on cutting conditions, tool material and wear of the cutting edge determined by the bevel rear tool wear. To ensure of the surface quality of the composite

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Blomberg, Johan. "The expression of non-actual motion in Swedish, French and Thai." Cognitive Linguistics 26, no. 4 (2015): 657–96. http://dx.doi.org/10.1515/cog-2015-0025.

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AbstractDynamic descriptions of static spatial situations, such as the road goes through the forest have attracted a lot of attention across different semantic theories. Analyses in terms of fictive motion and subjective motion have proposed that such expressions are strongly motivated by universal cognitive and conceptual factors. I present theoretical arguments for the conflation of several different motivations in the literature. Instead of a single general motivation, three distinct experiential motivations are presented under the term non-actual motion. These experiential motivations are

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Парфенов, Владимир, Vladimir Parfenov, Александр Хандожко, Alexandr Khandozhko, Алексей Киричек, and Alexey Kirichek. "DESIGN OF ROUGH HOBBING CUTTER FOR MACHINING OF COG-WHEEL OF LARGE MODULE." Bulletin of Bryansk state technical university 2019, no. 7 (2019): 23–29. http://dx.doi.org/10.30987/article_5d2d92319a8d00.64590625.

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For today cog-wheels are widespread parts in mechanical engineering. Hobbing cutters are to machine such parts with an efficient gear-cutting tool. For the preliminary machining of cog-wheel teeth of diesel locomotive wheel-pair m=10mm with the allowance for grinding there are used rough hobbing cutters. At that for the improvement of grinding conditions an allowance must be uneven: larger at the tooth top and less at the dedendum. Therefore special milling cutters are needed for machining cogwheels with the allowance for grinding. The existing solutions are not urgent in the field of limited

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Pudlo, Michael, Carl Daniel, Susan Bionat, Sayali Ketkar, and Arvind Bhimaraj. "Prevalence of Cognitive Impairment (CI) in Hospitalized Heart Failure (HF) Patients Utilizing the Mini-Cog Assessment Tool." Journal of Cardiac Failure 22, no. 8 (2016): S90. http://dx.doi.org/10.1016/j.cardfail.2016.06.287.

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DeVries, Michael J., and Sallie E. Gordon. "Estimating Cognitive Complexity and the Need for Cognitive Task Analysis." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 38, no. 16 (1994): 1023–27. http://dx.doi.org/10.1177/154193129403801607.

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Because an increasing number of systems are being developed to support complex cognitive functioning, task analysis is commonly being augmented with cognitive task analysis, which identifies cognitive processes, knowledge, and mental models relevant to task performance. Cognitive task analysis tends to be lengthy and time-consuming, so designers frequently ask how they might know if it is actually necessary for a specific project. In this paper, we assume that much of the need for cognitive task analysis depends on the inherent “cognitive complexity” of the task. We present a model of cognitiv

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Wommack, K. Eric, Jaysheel Bhavsar, and Jacques Ravel. "Metagenomics: Read Length Matters." Applied and Environmental Microbiology 74, no. 5 (2008): 1453–63. http://dx.doi.org/10.1128/aem.02181-07.

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ABSTRACT Obtaining an unbiased view of the phylogenetic composition and functional diversity within a microbial community is one central objective of metagenomic analysis. New technologies, such as 454 pyrosequencing, have dramatically reduced sequencing costs, to a level where metagenomic analysis may become a viable alternative to more-focused assessments of the phylogenetic (e.g., 16S rRNA genes) and functional diversity of microbial communities. To determine whether the short (∼100 to 200 bp) sequence reads obtained from pyrosequencing are appropriate for the phylogenetic and functional ch

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Sinclair, A. J., R. Gadsby, R. Hillson, A. Forbes, and A. J. Bayer. "Brief report: Use of the Mini-Cog as a screening tool for cognitive impairment in diabetes in primary care." Diabetes Research and Clinical Practice 100, no. 1 (2013): e23-e25. http://dx.doi.org/10.1016/j.diabres.2013.01.001.

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Yu, Chao, Fang Wang, Bingyu Wang, Guibing Li, and Fan Li. "A Computational Biomechanics Human Body Model Coupling Finite Element and Multibody Segments for Assessment of Head/Brain Injuries in Car-To-Pedestrian Collisions." International Journal of Environmental Research and Public Health 17, no. 2 (2020): 492. http://dx.doi.org/10.3390/ijerph17020492.

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It has been challenging to efficiently and accurately reproduce pedestrian head/brain injury, which is one of the most important causes of pedestrian deaths in road traffic accidents, due to the limitations of existing pedestrian computational models, and the complexity of accidents. In this paper, a new coupled pedestrian computational biomechanics model (CPCBM) for head safety study is established via coupling two existing commercial pedestrian models. The head–neck complex of the CPCBM is from the Total Human Model for Safety (THUMS, Toyota Central R&D Laboratories, Nagakute, Japan) (Ve

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Wong-Achi, Xavier, Gabriela Egas, and Dayana Cabrera. "Cognitive Impairment in Rural Elderly Population in Ecuador." Journal of Neurosciences in Rural Practice 08, S 01 (2017): S020—S022. http://dx.doi.org/10.4103/jnrp.jnrp_3_17.

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ABSTRACT Introduction: The Mini-Cog is a simple and short test that identifies cognitive impairment. Its detection helps provide an early dementia diagnosis, rapid access to treatments, and even delay or reversion. Materials and Methods: This multicenter, observational, descriptive, and cross-sectional study included 214 patients. Patients enrolled in this study were community dwellers aged ≥55-year-old, without prior diagnosis of cognitive impairment or dementia, with adequate hearing and vision functions. It was conducted in primary care health centers localized in rural communities of Ecuad

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Pérez-Cerdá, Celia, Dulce Quelhas, Ana I. Vega, Jesús Ecay, Laura Vilarinho, and Magdalena Ugarte. "Screening Using Serum Percentage of Carbohydrate-Deficient Transferrin for Congenital Disorders of Glycosylation in Children with Suspected Metabolic Disease." Clinical Chemistry 54, no. 1 (2008): 93–100. http://dx.doi.org/10.1373/clinchem.2007.093450.

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Abstract Background: Diagnoses of congenital disorders of glycosylation (CDG) are based on clinical suspicion and analysis of transferrin (Tf) isoforms. Here we present our experience of CDG screening in children with a suspected metabolic disease by determination of serum percentage of carbohydrate-deficient transferrin (%CDT) in tandem with isoelectric focusing (IEF) analysis of Tf and α1-antitrypsin (α1-AT). Methods: We performed approximately 8000 serum %CDT determinations using %CDT turbidimetric immunoassay (TIA). In selected samples, IEF analysis of Tf and α1-AT was carried out on an ag

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Galderisi, Faith C., Linda C. Stork, Ju Li, Motomi Mori, Solange Mongoue-Tchokote, and James Huang. "In Vitro Drug Sensitivity as a Predicitive Tool of Early Clinical Response in Childhood Acute Lymphoblastic Leukemia." Blood 110, no. 11 (2007): 4232. http://dx.doi.org/10.1182/blood.v110.11.4232.4232.

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Abstract Background: Residual disease or rapidity of response to induction therapy is among the most powerful predictors of outcome in pediatric Acute Lymphoblastic Leukemia (ALL). Various methods to determine response during induction have been in use in clinical investigation. We hypothesize that drug sensitivity at the cellular level predicts rapidity of response to induction therapy in ALL. We recently developed a high resolution flow cytometry based cytotoxicity assay for in vitro cellular drug response profiling for pediatric ALL. This method has a turnaround time of 48 hours and the abi

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Elsayed, Abdelrahman H., Huiyun Wu, Xueyuan Cao, et al. "A 5-Gene Ara-C, Daunorubicin and Etoposide (ADE) Drug Response Score As a Prognostic Tool to Predict AML Treatment Outcome." Blood 134, Supplement_1 (2019): 1429. http://dx.doi.org/10.1182/blood-2019-128787.

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Introduction: Cytarabine, daunorubicin and etoposide (ADE) are commonly used for remission and intensification of pediatric acute myeloid leukemia (AML). However, development of drug resistance is a major cause of treatment failure. In this study, we performed a comprehensive evaluation of expression levels of genes of pharmacological significance (pharmacokinetic /pharmacodynamic) to ADE and derived a drug response score predictive of treatment outcomes in pediatric AML patients. Methods: This study included 163 cases (median age=8.79 year, range= (0.013-21.1)) with AML enrolled in the multic

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Panhwar, Muhammad S., Megan E. Cunningham, Sadeer G. Al-Kindi, Joyce Thomas, Mriganka Singh, and Mahazarin Ginwalla. "High LACE Score with Abnormal Mini-Cog is a Strong Predictive Tool for All-Cause 30-Day Readmissions in Heart Failure Patients." Journal of Cardiac Failure 23, no. 8 (2017): S104—S105. http://dx.doi.org/10.1016/j.cardfail.2017.07.305.

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Fernández Bascuñana, Gema. "Validation of Authentication Measures Implementation in Iot Mobile Applications." Smart Cities 2, no. 2 (2019): 163–78. http://dx.doi.org/10.3390/smartcities2020012.

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Smartphones are an integral cog of the IoT environment and a fundamental bloc of any related security solution, given that IoT mobile applications allow users not only to get information, but also to influence the environment. This paper presents a methodological instrument that can contribute to implementing and evaluating security measures in mobile applications by means of an automated analysis tool. A clear process for linking policy and high-level security guidelines and measures to concrete source code elements is depicted, as well as an automated way of testing a set of mobile applicati

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Jeong, Min-Ki, Kyung-Won Park, Je-Kwang Ryu, Gwon-Min Kim, Hyun-Hun Jung, and Hyuntae Park. "Multi-Component Intervention Program on Habitual Physical Activity Parameters and Cognitive Function in Patients with Mild Cognitive Impairment: A Randomized Controlled Trial." International Journal of Environmental Research and Public Health 18, no. 12 (2021): 6240. http://dx.doi.org/10.3390/ijerph18126240.

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Age-related dementia refers to a state in which someone experiences multiple cognitive function impairment due to degenerative brain disease, and which causes difficulties in their daily life or social life. Dementia is the most common and serious obstacle in later life. Early intervention in the case of patients who are in the mild cognitive impairment (MCI) stage among the high-risk group can maintain and improve their cognitive function. The purpose of the current trial is aimed at investigating the association between a multi-component (exercise with cognitive) intervention program and hab

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Elsayed, Abdelrahman H., Huiyun Wu, Xueyuan Cao, et al. "Pediatric LSC3 (pLSC3) Score Derived from DNMT3B-CD34-GPR56 As a Prognostic Tool to Predict AML Patient Outcome: Results from Two Independent Pediatric AML Cohorts." Blood 132, Supplement 1 (2018): 290. http://dx.doi.org/10.1182/blood-2018-99-116462.

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Abstract Introduction: Resistance and relapse remain major obstacles in the treatment of acute myeloid leukemia (AML). Pre-existence and persistence of drug resistant leukemia stem cells (LSCs) is considered one of the major causes of relapse. A previous study (Ng et al., 2016) reported a prognostic signature of 17 genes (LSC17 score) differentially expressed in LSC+ compared to LSC- cell fractions that predicted outcome in patients with AML thereby classifying patients into high and low risk groups. The goal of this study is to determine the validity of LSC17 score in pediatric AML patients a

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Abro, Brooj, Cara Lunn Shirai, Anjum Hassan, Yvette Kudlinski, Barbara Weddle, and Friederike Kreisel. "Comparison of Immunophenotypic Abnormalities in B-Lymphoblastic Leukemia (B-ALL) Minimal Residual Disease (MRD) of Adults and Children Utilizing the Children's Oncology Group (COG)-Validated Multiparameter Flow Cytometry (MFC)- MRD Approach: An Institutional Experience." Blood 132, Supplement 1 (2018): 2661. http://dx.doi.org/10.1182/blood-2018-99-112317.

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Abstract Introduction Detection of minimal residual disease (MRD) by multiparameter flow cytometry (MFC) has become an important clinical tool in the treatment of patients with acute leukemia. At our institution, we routinely employ Children's Oncology Group (COG) validated B-lymphoblastic leukemia (B-ALL) MFC-MRD analysis for the detection of MRD in pediatric patients after induction therapy for B-ALL. We have extended this COG-validated assay to the adult B-ALL population. This technique relies on the identification of aberrant immunophenotypes expressed by residual bone marrow B-lymphoblast

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Mohile, Supriya G., William Dale, Mark R. Somerfield, et al. "Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology." Journal of Clinical Oncology 36, no. 22 (2018): 2326–47. http://dx.doi.org/10.1200/jco.2018.78.8687.

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Purpose To provide guidance regarding the practical assessment and management of vulnerabilities in older patients undergoing chemotherapy. Methods An Expert Panel was convened to develop clinical practice guideline recommendations based on a systematic review of the medical literature. Results A total of 68 studies met eligibility criteria and form the evidentiary basis for the recommendations. Recommendations In patients ≥ 65 years receiving chemotherapy, geriatric assessment (GA) should be used to identify vulnerabilities that are not routinely captured in oncology assessments. Evidence sup

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Ketelaars⁎, L., L. Pottel, M. Lycke, et al. "Use of the Freund Clock Drawing Test within the Mini-Cog as a screening tool for cognitive impairment in elderly patients with or without cancer." Journal of Geriatric Oncology 3 (October 2012): S75. http://dx.doi.org/10.1016/j.jgo.2012.10.083.

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Ketelaars, Lore, Lies Pottel, Michelle Lycke, et al. "Use of the Freund Clock Drawing Test within the Mini-Cog as a screening tool for cognitive impairment in elderly patients with or without cancer." Journal of Geriatric Oncology 4, no. 2 (2013): 174–82. http://dx.doi.org/10.1016/j.jgo.2012.10.175.

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Camargo, Carlos Henrique Ferreira, Rafael Arthur Serpa, Thiago Matnei, Jivago Szpoganicz Sabatini, and Hélio Afonso Ghizoni Teive. "The perception of apathy by caregivers of patients with dementia in Parkinson's disease." Dementia & Neuropsychologia 10, no. 4 (2016): 339–43. http://dx.doi.org/10.1590/s1980-5764-2016dn1004014.

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ABSTRACT Background: Apathy is one of the main neuropsychiatric symptoms in patients with Parkinson's disease (PD) and is associated with Parkinson's disease dementia (PDD). Objective: To identify the characteristics of apathy in individuals with PDD according to caregiver perception. Methods: Thirty-nine patients with PD according to MDS criteria for PDD were included. The following scales were used: the Hoehn and Yahr, the Unified Parkinson's Disease Rating Scale III, Scales for Outcomes in Parkinson's Disease-Cognition (SCOPA Cog), the Montgomery-Åsberg Depression Rating Scale (MADRS) and t

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