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1

Swenor, Bonnielin, beatriz Munoz, and Eleanor M. Simonsick. "VISUAL IMPAIRMENT AND ENGAGEMENT IN COGNITIVELY STIMULATING ACTIVITIES." Innovation in Aging 3, Supplement_1 (November 2019): S656. http://dx.doi.org/10.1093/geroni/igz038.2432.

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Abstract We examined the relationship between visual impairment (VI) and engagement in cognitively stimulating activities using data from 924 participants in the Cognitive Vitality Sub-Study of the Health ABC Study. At Year 3 (baseline for these analyses), vision was assessed as: visual acuity (VA), contrast sensitivity (CS), and stereo acuity (SA). Participation in cognitively stimulating activities was determined based on responses to 12 questions (administered at Years 3, 5, 7, and 9) assessing frequency of participation ranging from none to daily. We calculated the total number of activities engaged in at least monthly. In cross-sectional analyses adjusted for age, race, and sex, impaired VA (≤20/40, 8%), CS (<1.55, 5%), and SA (<80 secs arc, 29%) was associated with participation in fewer cognitive activities (β=-0.54, 95% CI:-1.06, -0.03; β=-0.59, 95% CI:-0.12, 0.06; β=-0.40, 95% CI:-0.81, -0.18, respectively). Longitudinally, change per year in the number of activities differed by baseline participation levels. Those participating in ≥5 activities at baseline (population median) had a significant decline in the number of activities, irrespective of VI status. However, for those participating in <5 activities at baseline, the increase in these activities tended to be lesser in the VI than in non-VI groups, and for SA this increase was significantly lower for the impaired group (βimpaired=0.004; 95% CI:-0.05, 0.05; βnot-impaired=0.06; 95% CI: 0.03, 0.10; time x SA interaction p=0.0496). These data indicate that older adults with VI participate in fewer cognitive activities and the change in participation over time differs from than those without VI.
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2

Farah, Martha J., Saul Sternberg, Thomas A. Nichols, Jeffrey T. Duda, Terry Lohrenz, Yi Luo, Libbie Sonnier, Sharon L. Ramey, Read Montague, and Craig T. Ramey. "Randomized Manipulation of Early Cognitive Experience Impacts Adult Brain Structure." Journal of Cognitive Neuroscience 33, no. 6 (May 1, 2021): 1197–209. http://dx.doi.org/10.1162/jocn_a_01709.

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Abstract Does early exposure to cognitive and linguistic stimulation impact brain structure? Or do genetic predispositions account for the co-occurrence of certain neuroanatomical phenotypes and a tendency to engage children in cognitively stimulating activities? Low socioeconomic status infants were randomized to either 5 years of cognitively and linguistically stimulating center-based care or a comparison condition. The intervention resulted in large and statistically significant changes in brain structure measured in midlife, particularly for male individuals. These findings are the first to extend the large literature on cognitive enrichment effects on animal brains to humans, and to demonstrate the effects of uniquely human features such as linguistic stimulation.
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3

Wilson, Robert S., Lisa L. Barnes, and David A. Bennett. "Assessment of Lifetime Participation in Cognitively Stimulating Activities." Journal of Clinical and Experimental Neuropsychology 25, no. 5 (August 1, 2003): 634–42. http://dx.doi.org/10.1076/jcen.25.5.634.14572.

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4

Vemuri, P., and E. C. Mormino. "Cognitively stimulating activities to keep dementia at bay." Neurology 81, no. 4 (July 3, 2013): 308–9. http://dx.doi.org/10.1212/wnl.0b013e31829c5f05.

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5

Baldivia, Beatriz, Vivian Maria Andrade, and Orlando Francisco Amodeo Bueno. "Contribution of education, occupation and cognitively stimulating activities to the formation of cognitive reserve." Dementia & Neuropsychologia 2, no. 3 (September 2008): 173–82. http://dx.doi.org/10.1590/s1980-57642009dn20300003.

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Abstract The cognitive reserve (CR) concept posits that there is individual variability in processing task demands and coping with neurodegenerative diseases. This variability can be attributed to the protective effects derived from continuous cognitive stimulation throughout life, including formal education, engagement in cognitively stimulating activities and occupation. These can result in protection against age-related cognitive decline and reduce the risk of developing Alzheimer's disease. The aim of this review is to summarize the main features of CR formation and to discuss the challenges in carrying out CR research in developing countries.
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Tesky, Valentina A., Christian Thiel, Winfried Banzer, and Johannes Pantel. "Effects of a Group Program to Increase Cognitive Performance Through Cognitively Stimulating Leisure Activities in Healthy Older Subjects." GeroPsych 24, no. 2 (June 2011): 83–92. http://dx.doi.org/10.1024/1662-9647/a000035.

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To investigate the effects of leisure activities on cognitive performance of healthy older subjects, an innovative intervention program was developed. Frequent participation in cognitively stimulating activities (i.e., reading, playing chess, or playing music) is associated with reduced risk of dementia. AKTIVA (active cognitive stimulation – prevention in the elderly) is an intervention program designed to enhance cognitive stimulation in everyday life by increasing cognitive stimulating leisure activities. The present study determines the effects of AKTIVA on cognitive function, mood and attitude toward aging in a sample of older participants from the general population. Several measurement instruments were used including the Alzheimer’s Disease Assessment Scale (ADAS-Cog), the Trail-Making Test (TMT), and the Memory Complaint Questionnaire (MAC-Q). Initially, the sample consisted of 307 older persons (170 female, 72 ± 7 years). The intervention was evaluated with a randomized, controlled pre-post follow-up design. Participants were randomly assigned to one of three conditions: AKTIVA intervention (n = 126), AKTIVA intervention plus nutrition and exercise counseling (n = 84), no-intervention control group (n = 97). The AKTIVA intervention consisted of 8 weekly sessions and two booster sessions after a break of 4 months. Participation in the group program resulted in positive effects on cognitive function and attitude toward aging for subassembly groups. Older persons (≥ 75 years) showed enhanced speed of information processing (by TMT Version A) (F = 4.17*, p < .05); younger participants (< 75 years) showed an improvement in subjective memory decline (by MAC-Q) (F = 2.55*, p < .05). Additionally, AKTIVA enhanced the frequency of activities for leisure activities for subassembly groups. The results of this study suggest that the AKTIVA program can be used to increase cognitively stimulating leisure activities in the elderly. Further research is necessary to identify the long-term effects of this intervention particularly with respect to the prevention of dementia.
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7

Ferreira, Nicola, Adrian Owen, Anita Mohan, Anne Corbett, and Clive Ballard. "Associations between cognitively stimulating leisure activities, cognitive function and age-related cognitive decline." International Journal of Geriatric Psychiatry 30, no. 4 (July 3, 2014): 422–30. http://dx.doi.org/10.1002/gps.4155.

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8

Morales Ortiz, Manuel, and Aaron Fernández. "Assessment of Cognitively Stimulating Activity in a Spanish Population." Assessment 27, no. 6 (May 21, 2018): 1310–19. http://dx.doi.org/10.1177/1073191118774620.

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Theoretical models of active ageing and cognitive reserve emphasize the importance of leading an active life to delay age-related cognitive deterioration and maintain good levels of well-being and personal satisfaction in the elderly. The objective of this research was to construct a scale to measure cognitively stimulating activities (CSA) in the Spanish language. The sample consisted of a total of 453 older persons. The scale was constructed from a list of 28 items and validated using structural equation models. The scale obtained showed a negative correlation with age and a positive correlation with education and physical activity. Using hierarchical regression models, CSAs were found to have a significant effect on attention when controlling for the effect of age and education. Likewise, a significant interaction between age and CSA was found on the measure of episodic memory. The validated CSA scale will enable the relationships between changes in cognitive functions and stimulating activities to be studied.
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9

Pillai, Jagan A., Charles B. Hall, Dennis W. Dickson, Herman Buschke, Richard B. Lipton, and Joe Verghese. "Association of Crossword Puzzle Participation with Memory Decline in Persons Who Develop Dementia." Journal of the International Neuropsychological Society 17, no. 6 (September 28, 2011): 1006–13. http://dx.doi.org/10.1017/s1355617711001111.

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AbstractParticipation in cognitively stimulating leisure activities such as crossword puzzles may delay onset of the memory decline in the preclinical stages of dementia, possibly via its effect on improving cognitive reserve. We followed 488 initially cognitively intact community residing individuals with clinical and cognitive assessments every 12–18 months in the Bronx Aging Study. We assessed the influence of crossword puzzle participation on the onset of accelerated memory decline as measured by the Buschke Selective Reminding Test in 101 individuals who developed incident dementia using a change point model. Crossword puzzle participation at baseline delayed onset of accelerated memory decline by 2.54 years. Inclusion of education or participation in other cognitively stimulating activities did not significantly add to the fit of the model beyond the effect of puzzles. Our findings show that late life crossword puzzle participation, independent of education, was associated with delayed onset of memory decline in persons who developed dementia. Given the wide availability and accessibility of crossword puzzles, their role in preventing cognitive decline should be validated in future clinical trials. (JINS, 2011, 17, 1006–1013)
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10

Qiu, Chengxuan, and Laura Fratiglioni. "Frequent cognitively stimulating activities reduces the risk of Alzheimer disease." Evidence-based Healthcare 6, no. 3 (September 2002): 113–14. http://dx.doi.org/10.1054/ebhc.2002.0510.

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11

Opdebeeck, Carol, Catherine Quinn, Sharon M. Nelis, and Linda Clare. "Does cognitive reserve moderate the association between mood and cognition? A systematic review." Reviews in Clinical Gerontology 25, no. 3 (August 2015): 181–93. http://dx.doi.org/10.1017/s0959259815000155.

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SummaryThe evidence regarding the association between mood and cognitive function is conflicting, suggesting the involvement of moderating factors. This systematic review aimed to assess whether cognitive reserve moderates the association between mood and cognition in older people. Cognitive reserve was considered in terms of the three key proxy measures – educational level, occupation, and engagement in cognitively stimulating leisure activities – individually and in combination. Sixteen studies representing 37,101 participants were included in the review. Of these, 13 used a measure of education, one used a measure of occupation, two used a measure of participation in cognitively stimulating activities, and one used a combination of these. In general, cognitive reserve moderated the association between mood and cognition, with a larger negative association between mood and cognition in those with low cognitive reserve than in those with high cognitive reserve. Further research utilizing multiple proxy measures of cognitive reserve is required to elucidate the associations.
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12

Hassing, Linda B. "Gender Differences in the Association Between Leisure Activity in Adulthood and Cognitive Function in Old Age: A Prospective Longitudinal Population-Based Study." Journals of Gerontology: Series B 75, no. 1 (September 4, 2017): 11–20. http://dx.doi.org/10.1093/geronb/gbx170.

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Abstract Objectives To examine the long-term association between leisure activities in adulthood and cognitive function in old age while recognizing gender differences in activity profiles. Methods The sample included 340 cognitively healthy twins enrolled in the OCTO-Twin Study, a longitudinal study on cognitive aging. Leisure activity was measured in midlife and cognitive function in old age (mean age 83). Leisure activities covered the domains of domestic, intellectual–cultural, and self-improvement activities. The cognitive assessments comprised 5 measurement occasions (2-year intervals) covering verbal ability, spatial ability, memory, and speed. The association between leisure activity and cognitive function was estimated separately for the genders using growth curve models, adjusting for age and education. Results Men and women had the same level of total leisure activity but differed in activity profiles and in the associations between activity and cognitive function. Higher engagement in self-improvement among men was related to higher level of cognitive functioning. Among women, intellectual–cultural activity was related to better verbal ability and memory. Concerning trajectories of cognitive function, domestic activity among men was related to less decline in speed, whereas for women it was related to steeper decline in spatial ability and memory. Further, higher intellectual–cultural activity among women was related to steeper decline in memory. Discussion Cognitively stimulating activities (i.e., self-improvement and intellectual–cultural), might increase cognitive reserve whereas less cognitively stimulating activities (i.e., domestic) do not. Gender differences should be considered when examining lifestyle factors in relation to cognitive aging.
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13

Mitchell, Meghan B., Cynthia R. Cimino, Andreana Benitez, Cassandra L. Brown, Laura E. Gibbons, Robert F. Kennison, Steven D. Shirk, et al. "Cognitively Stimulating Activities: Effects on Cognition across Four Studies with up to 21 Years of Longitudinal Data." Journal of Aging Research 2012 (2012): 1–12. http://dx.doi.org/10.1155/2012/461592.

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Engagement in cognitively stimulating activities has been considered to maintain or strengthen cognitive skills, thereby minimizing age-related cognitive decline. While the idea that there may be a modifiable behavior that could lower risk for cognitive decline is appealing and potentially empowering for older adults, research findings have not consistently supported the beneficial effects of engaging in cognitively stimulating tasks. Using observational studies of naturalistic cognitive activities, we report a series of mixed effects models that include baseline and change in cognitive activity predicting cognitive outcomes over up to 21 years in four longitudinal studies of aging. Consistent evidence was found for cross-sectional relationships between level of cognitive activity and cognitive test performance. Baseline activity at an earlier age did not, however, predict rate of decline later in life, thus not supporting the concept that engaging in cognitive activity at an earlier point in time increases one's ability to mitigate future age-related cognitive decline. In contrast, change in activity was associated with relative change in cognitive performance. Results therefore suggest that change in cognitive activity from one's previous level has at least a transitory association with cognitive performance measured at the same point in time.
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14

Ihle, Andreas, Michel Oris, Delphine Fagot, Christian Maggiori, and Matthias Kliegel. "The association of educational attainment, cognitive level of job, and leisure activities during the course of adulthood with cognitive performance in old age: the role of openness to experience." International Psychogeriatrics 28, no. 5 (November 26, 2015): 733–40. http://dx.doi.org/10.1017/s1041610215001933.

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ABSTRACTBackground:The relevance of mental health for everyday life functioning and well-being is crucial. In this context, higher educational attainment, higher cognitive level of one's occupation, and more engaging in stimulating leisure activities have been found to be associated with better cognitive functioning in old age. Yet, the detailed pattern of the potential interplay of such a cognitively engaged lifestyle with personality dimensions, such as openness to experience, in their relations to cognitive functioning remains unclear.Methods:Two thousand eight hundred and twelve older adults served as sample for the present study. Psychometric tests on verbal abilities and processing speed were administered. In addition, individuals were retrospectively interviewed on their educational attainment, occupation, and regarding 18 leisure activities that had been carried out in mid-life. Moreover, openness to experience was assessed.Results:We found that the effect of openness to experience on cognitive functioning was mediated by educational attainment, cognitive level of job, and engaging in different leisure activities. Data were not better described by alternative moderation models testing for interactive (i.e. dependent) effects of openness to experience and cognitively stimulating engagement.Conclusions:To explain interindividual differences in cognitive functioning in old age, present data are in line with a mechanism in which individuals with high openness to experience may have been more engaged in stimulating activities in early and mid-life. Possibly by increasing their cognitive reserve throughout adulthood, this may finally enhance their cognitive performance level later in old age.
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15

Cohen, Ann D., Beth E. Snitz, Eric McDade, Howard J. Aizenstein, Julie Price, Chester Mathis, Oscar L. Lopez, and William Klunk. "O3-01-06: Effect of cognitively stimulating activities on PiB-PET in cognitively normal elderly." Alzheimer's & Dementia 11, no. 7S_Part_5 (July 2015): P219. http://dx.doi.org/10.1016/j.jalz.2015.07.241.

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16

WILSON, ROBERT S., LISA L. BARNES, KRISTIN R. KRUEGER, GEORGE HOGANSON, JULIA L. BIENIAS, and DAVID A. BENNETT. "Early and late life cognitive activity and cognitive systems in old age." Journal of the International Neuropsychological Society 11, no. 4 (July 2005): 400–407. http://dx.doi.org/10.1017/s1355617705050459.

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Little is known about the relative benefits of cognitively stimulating activities at different points in the lifespan. In a cohort of 576 older persons without dementia, we assessed current and past (childhood, young adulthood, middle age) frequency of cognitive activity; availability of cognitively stimulating resources in the home in childhood and middle age; and 5 domains of cognitive function. Past cognitive activity and cognitive resources were positively correlated with both current cognitive activity and current cognitive function. The association with cognitive function was reduced after controlling for current cognitive activity, however. Current cognitive activity was associated with better cognitive function, especially semantic memory and perceptual speed, even after controlling for past activity. The results suggest that past cognitive activity contributes to current cognition principally through its association with cognitive activity in old age. (JINS, 2005,11, 400–407.)
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17

Wilson, Robert S. "Participation in Cognitively Stimulating Activities and Risk of Incident Alzheimer Disease." JAMA 287, no. 6 (February 13, 2002): 742. http://dx.doi.org/10.1001/jama.287.6.742.

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18

Campbell, Laura M., Emily W. Paolillo, Anne Heaton, Bin Tang, Colin A. Depp, Eric Granholm, Robert K. Heaton, Joel Swendsen, David J. Moore, and Raeanne C. Moore. "Daily Activities Related to Mobile Cognitive Performance in Middle-Aged and Older Adults: An Ecological Momentary Cognitive Assessment Study." JMIR mHealth and uHealth 8, no. 9 (September 24, 2020): e19579. http://dx.doi.org/10.2196/19579.

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Background Daily activities have been associated with neurocognitive performance. However, much of this research has used in-person neuropsychological testing that requires participants to travel to a laboratory or clinic, which may not always be feasible and does not allow for the examination of real-time relationships between cognition and behavior. Thus, there is a need to understand the real-time relationship between activities in the real world and neurocognitive functioning to improve tracking of symptoms or disease states and aid in the early identification of neurocognitive deficits among at-risk individuals. Objective We used a smartphone-based ecological momentary cognitive assessment (EMCA) platform to examine real-time relationships between daily activities and neurocognitive performance (executive functioning and verbal learning) in the everyday environment of middle-aged and older adults with and without HIV. Methods A total of 103 adults aged 50-74 years (67 persons with HIV; mean age 59 years, SD 6.4) were recruited from the University of California, San Diego HIV Neurobehavioral Research Program and the San Diego community. Participants completed our EMCA protocol for 14 days. Participants reported their current daily activities 4 times per day; following 2 of the 4 daily ecological momentary assessment (EMA) surveys, participants were administered the mobile Color-Word Interference Test (mCWIT) and mobile Verbal Learning Test (mVLT), each once per day. Activities were categorized into cognitively stimulating activities, passive leisure activities, and instrumental activities of daily living (IADLs). We used multilevel modeling to examine the same-survey and lagged within-person and between-person effects of each activity type on mobile cognitive performance. Results On average, participants completed 91% of the EMA surveys, 85% of the mCWIT trials, and 80% of the mVLT trials, and they reported engaging in cognitively stimulating activities on 17% of surveys, passive leisure activities on 33% of surveys, and IADLs on 20% of surveys. Adherence and activity percentages did not differ by HIV status. Within-persons, engagement in cognitively stimulating activities was associated with better mCWIT performance (β=−1.12; P=.007), whereas engagement in passive leisure activities was associated with worse mCWIT performance (β=.94; P=.005). There were no lagged associations. At the aggregate between-person level, a greater percentage of time spent in cognitively stimulating activities was associated with better mean mVLT performance (β=.07; P=.02), whereas a greater percentage of time spent in passive leisure activities was associated with worse mean mVLT performance (β=−.07; P=.01). IADLs were not associated with mCWIT or mVLT performance. Conclusions Smartphones present unique opportunities for assessing neurocognitive performance and behavior in middle-aged and older adults’ own environment. Measurement of cognition and daily functioning outside of clinical settings may generate novel insights on the dynamic association of daily behaviors and neurocognitive performance and may add new dimensions to understanding the complexity of human behavior.
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Mather, Mara. "How Do Cognitively Stimulating Activities Affect Cognition and the Brain Throughout Life?" Psychological Science in the Public Interest 21, no. 1 (August 2020): 1–5. http://dx.doi.org/10.1177/1529100620941808.

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Cohen, Ann, Beth Snitz, Oscar Lopez, Howard Aizenstein, Robert Nebes, Lisa Weissfeld, Julie Price, Chester Mathis, and William Klunk. "P2-133: Effect of cognitively and physically stimulating activities on PiB-PET." Alzheimer's & Dementia 9 (July 2013): P394. http://dx.doi.org/10.1016/j.jalz.2013.05.777.

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Wilson, Robert S., and David A. Bennett. "Cognitive Activity and Risk of Alzheimer's Disease." Current Directions in Psychological Science 12, no. 3 (June 2003): 87–91. http://dx.doi.org/10.1111/1467-8721.01236.

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Recent research suggests that frequent participation in cognitively stimulating activities may reduce risk of Alzheimer's disease in old age. We review epidemiological evidence of such an association. We then consider whether cognitive activity can account for the association between higher educational and occupational attainment and reduced risk of Alzheimer's disease. Finally, we discuss the behavioral and neurobiological mechanisms that may underlie the association between cognitive activity and risk of Alzheimer's disease.
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Tesky, Valentina, and Johannes Pantel. "P3-321: Cognitively stimulating leisure activities: A new approach for patients with mild cognitive impairment (MCI)." Alzheimer's & Dementia 8, no. 4S_Part_15 (July 2012): P571. http://dx.doi.org/10.1016/j.jalz.2012.05.1545.

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23

Daffner, Kirk R., Katherine K. Ryan, Danielle M. Williams, Andrew E. Budson, Dorene M. Rentz, David A. Wolk, and Phillip J. Holcomb. "Increased Responsiveness to Novelty is Associated with Successful Cognitive Aging." Journal of Cognitive Neuroscience 18, no. 10 (October 2006): 1759–73. http://dx.doi.org/10.1162/jocn.2006.18.10.1759.

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The animal literature suggests that exposure to more complex, novel environments promotes neurogenesis and cognitive performance in older animals. Studies in humans indicate that participation in intellectually stimulating activities may serve as a buffer against mental decline and help to sustain cognitive abilities. Here, we show that across old adults, increased responsiveness to novel events (as measured by viewing duration and the size of the P3 event-related potential) is strongly linked to better performance on neuropsychological tests, especially those involving attention/executive functions. Cognitively high performing old adults generate a larger P3 response to visual stimuli than cognitively average performing adults. These results suggest that cognitively high performing adults successfully manage the task by appropriating more resources and that the increased size of their P3 component represents a beneficial compensatory mechanism rather than less efficient processing.
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Roth, Nicole, Paola Sebastiani, Stephanie Cosentino, Nicole Schupf, Thomas Perls, and Stacy Andersen. "Pathway Analysis of Leisure Activity and Cognitive Function in the Long Life Family Study." Innovation in Aging 4, Supplement_1 (December 1, 2020): 501. http://dx.doi.org/10.1093/geroni/igaa057.1618.

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Abstract Familial longevity and greater involvement in activities purported to build cognitive reserve (e.g. education, cognitively stimulating leisure activity) have both been associated with better cognitive function in later life, yet little is known about how these protective factors relate with one another. In this work, we modeled the associations among familial longevity, proxies of cognitive reserve, and cognitive function in the Long Life Family Study (LLFS). We assessed cognitive function using a comprehensive battery of neuropsychological tests (i.e. Digit-Spans, California Verbal Learning Test, Rey-Osterrieth Complex Figure, phonemic fluency, category fluency, Word Generation, DKEFS Sorting Test, and logical memory) in a subset of LLFS family members and a referent cohort (N=314, mean age 75.7±14.6 years). To model these associations, we used a series of Bayesian hierarchical regression pathways that incorporate a random effect for family relatedness, adjusted by age and sex. All continuous variables were rescaled and bounded to be approximately between (0,1) in order to standardize regression coefficients and to allow for an asymmetrical beta-distribution. Controlling for education level, age, and sex, referents had greater engagement in late-life cognitive activities compared to LLFS family members, β=0.38 (95% CI: 0.18 to 0.57). In turn, those with higher markers of cognitive reserve exhibited better neuropsychological performance. Despite LLFS family members having lower participation in cognitively stimulating leisure activities, there were no differences between LLFS family members and referents on cognitive test performance. These results suggest long-lived family members may have more unique pathways (i.e. genetic/environmental) that preserve cognition later in life.
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Cohen, Ann, Beth Snitz, Oscar Lopez, Howard Aizenstein, Robert Nebes, Lisa Weissfeld, Julie Price, Chester Mathis, and William Klunk. "IC-P-030: Effect of cognitively and physically stimulating activities on PiB-PET." Alzheimer's & Dementia 9 (July 2013): P25. http://dx.doi.org/10.1016/j.jalz.2013.05.031.

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Schultz, Stephanie A., Jordan Larson, Jennifer Oh, Rebecca Koscik, Maritza N. Dowling, Catherine L. Gallagher, Cynthia M. Carlsson, et al. "Participation in cognitively-stimulating activities is associated with brain structure and cognitive function in preclinical Alzheimer’s disease." Brain Imaging and Behavior 9, no. 4 (October 31, 2014): 729–36. http://dx.doi.org/10.1007/s11682-014-9329-5.

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Meza, Pamela Almeida, Andrew Steptoe, and Dorina Cadar. "The Role of Leisure Activities as Markers of Cognitive Reserve on Dementia Risk in English Older Adults." Innovation in Aging 4, Supplement_1 (December 1, 2020): 664. http://dx.doi.org/10.1093/geroni/igaa057.2297.

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Abstract We examined the frequency of participation in cognitive and social type of leisure activities in association with dementia risk over 15 years of follow-up in 12,280 participants aged 50+ from the English Longitudinal Study of Ageing. Cox proportional hazards regression models were used to estimate the hazard of dementia in relation to the cognitive and social type of leisure activities as well as their interactions with sex and marital status. Medium and higher levels of engagement in cognitive leisure activities were associated with a lower risk of dementia. An analysis of the social type of leisure activities showed a similar pattern with protection for higher levels of engagement in a model adjusted for sex and marital status but further explained by wealth. This study shows a reduced risk of dementia for individuals with higher levels of engagement in cognitively stimulating activities, that may preserve cognitive reserve until later in life.
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Bronte-Tinkew, Jacinta, Jennifer Carrano, Allison Horowitz, and Akemi Kinukawa. "Involvement Among Resident Fathers and Links to Infant Cognitive Outcomes." Journal of Family Issues 29, no. 9 (January 8, 2008): 1211–44. http://dx.doi.org/10.1177/0192513x08318145.

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Using a sample of resident fathers in the Early Childhood Longitudinal Study–Birth Cohort (9-month Father Study), this study examined how father involvement is associated with infant cognitive outcomes in two domains (babbling and exploring objects with a purpose). Results from a series of logistic regression models indicate that varied aspects of father involvement (cognitively stimulating activities, physical care, paternal warmth, and caregiving activities) are associated with a lower likelihood of infant cognitive delay. Two-way interaction models further indicate that father involvement is related to greater reductions in infant cognitive delay for male infants than for female infants and for infants with disabilities than for infants without. These findings point to the importance of considering fathers' roles in early infant outcomes. Early positive father–child interactions reduce cognitive delay.
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Williams, Benjamin David, Neil Pendleton, and Tarani Chandola. "Cognitively stimulating activities and risk of probable dementia or cognitive impairment in the English Longitudinal Study of Ageing." SSM - Population Health 12 (December 2020): 100656. http://dx.doi.org/10.1016/j.ssmph.2020.100656.

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Krell-Roesch, Janina, Jeremy A. Syrjanen, Maria Vassilaki, Mary M. Machulda, Michelle M. Mielke, David S. Knopman, Walter K. Kremers, Ronald C. Petersen, and Yonas E. Geda. "Quantity and quality of mental activities and the risk of incident mild cognitive impairment." Neurology 93, no. 6 (July 10, 2019): e548-e558. http://dx.doi.org/10.1212/wnl.0000000000007897.

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ObjectiveTo investigate whether timing, number, and frequency of mentally stimulating activities in midlife and late life are associated with the risk of incident mild cognitive impairment (MCI).MethodsWe conducted a prospective cohort study in the setting of the population-based Mayo Clinic Study of Aging in Olmsted County, Minnesota, including 2,000 individuals aged ≥70 years who were cognitively unimpaired at baseline and were followed for a median of 5.0 years. Participants completed a self-reported survey on timing, number, and frequency of engagement in 5 mentally stimulating activities (reading books, computer use, social activities, playing games, craft activities) at baseline.ResultsThe risk of incident MCI was significantly reduced for participants who engaged in social activities (hazard ratio [95% confidence interval] 0.80 [0.64–0.99]) and playing games (0.80 [0.66–0.98]) in both late life and midlife combined. Using a computer was associated with a decreased risk regardless of timing (not late life but midlife: 0.52 [0.31–0.88]; late life but not midlife: 0.70 [0.56–0.88]; late life and midlife: 0.63 [0.51–0.79]). Craft activities were associated with a reduced risk of incident MCI only when carried out in late life but not midlife (0.58 [0.34–0.97]). Furthermore, engaging in a higher number of activities in late life was associated with a significantly reduced risk of incident MCI (any 2 activities: 0.72 [0.53–0.99], any 3: 0.55 [0.40–0.77], any 4: 0.44 [0.30–0.65], all 5: 0.57 [0.34–0.96]).ConclusionEngaging in a higher number of mentally stimulating activities, particularly in late life, is associated with a decreased risk of MCI among community-dwelling older persons.
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Brown, Colette, Andrea Chirino, Cristina Cortez, and Cassandra Gearhart. "I’m Not Creative in That Way: Older Adults’ Differential Experiences of an Arts-Based Intervention." Innovation in Aging 4, Supplement_1 (December 1, 2020): 835. http://dx.doi.org/10.1093/geroni/igaa057.3058.

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Abstract A recent 12-week intervention study revealed that making conceptual art is linked to improved cognitive health among community-dwelling older adults (Brown et al., 2020). Unknown, however, is whether the intervention experience differed for participants who exhibited more versus less improvement. This pilot study examined 163 excerpts from semi-structured interviews with cognitively normal, older adult participants (N = 11, Mean age = 72.82). Using thematic analysis and data displays on Dedoose, key themes were distilled regarding intervention acceptability. Participants exhibiting less cognitive improvement more often mentioned personally connecting to topics of dementia and aging through art, but more often mentioned scheduling conflicts. Conversely, participants exhibiting greater cognitive improvement more often mentioned experiencing intellectual enrichment, but feeling insecure about their art capabilities. Novel art activities may be personally meaningful and cognitively stimulating for some participants, but emotionally frustrating for others. Future work should explore ways to optimize arts-based interventions for older participants.
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Zhang, Wei. "Religious Participation, Gender Differences, and Cognitive Impairment among the Oldest-Old in China." Journal of Aging Research 2010 (2010): 1–10. http://dx.doi.org/10.4061/2010/160294.

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This study examines if religious participation in China is associated with cognitive functioning among the oldest-old and whether positive psychological feelings and leisure activity engagement explain the association, and gender moderates the association. Logistic regressions were used to analyze the Chinese Healthy Longevity Survey. A significant negative association between religious participation and cognitive impairment was found among the oldest-old and much of the association was mediated by positive psychological feelings and leisure activities. Women reported higher proportion of religious participation, but the cognitive benefits of religious participation were stronger for men. Findings indicate that (a) religious participation is significantly correlated with cognitive functioning in part because the religious oldest-old are more likely to be optimistic and happy and engage in more cognitively stimulating activities; (b) there might be gender differences in religious participation such that the oldest-old men may engage in religious activities that are particularly relevant to cognitive functioning.
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Yates, Lauren A., Shier Ziser, Aimee Spector, and Martin Orrell. "Cognitive leisure activities and future risk of cognitive impairment and dementia: systematic review and meta-analysis." International Psychogeriatrics 28, no. 11 (August 9, 2016): 1791–806. http://dx.doi.org/10.1017/s1041610216001137.

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ABSTRACTBackground:As life expectancies continue to rise, modifiable lifestyle factors that may prevent cognitive decline and dementia in later life become increasingly important in order to maintain quality of life in old age.Methods:Five meta-analyses were conducted on data from papers identified in a systematic review. Studies were grouped according to outcomes (dementia, cognitive impairment including amnestic Mild Cognitive Impairment (aMCI), Mild Cognitive Impairment (MCI), and cognitive decline) and output (risk (RR), odds (OR), or hazard ratios (HR)).Results:Nineteen studies met our inclusion criteria and quality assessments. Four of five meta-analyses showed significant associations between participation in cognitive leisure activities and reduced risk of cognitive impairment (OR = 0.69, 95% CI: 0.56–0.85) and dementia (HR = 0.58, 95% CI: 0.46–0.74; RR = 0.61, 95% CI: 0.42–0.90; OR = 0.78, 95% CI: 0.67–0.90). However, one pooled analysis of cognitive impairment studies did not reach significance (HR = 0.85, 95% CI: 0.71–1.02). Mentally stimulating leisure activities were significantly associated with later life cognition (β = 0.11, p = 0.05), better memory (β = 0.20, 95% CI: 0.11–0.29), speed of processing (β = 0.37, 95% CI: 0.29–0.45), and executive functioning (β = 0.23, 95% CI: 0.15–0.29), and less decline in overall cognition (β = −0.23, p < 0.01), language (β = −0.11, p < 0.05), and executive functioning (β = −0.13, p < 0.05). Activities were also shown to reduce rate of cognitive decline (estimate = 0.03, SE = 0.01, p = 0.00).Conclusions:There is increasing evidence that participation in cognitively stimulating leisure activities may contribute to a reduction of risk of dementia and cognitive impairment in later life. Promoting involvement in such activities across lifespan could be an important focus for primary prevention strategies for governments and health services.
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Larson, Jordan, Stephanie Schultz, Jennifer Oh, Rebecca L. Koscik, Maritza Dowling, Catherine Gallagher, Cynthia Carlsson, et al. "P2-204: PARTICIPATION IN COGNITIVELY-STIMULATING ACTIVITIES IS ASSOCIATED WITH BRAIN STRUCTURE AND COGNITIVE FUNCTION IN PRECLINICAL ALZHEIMER'S DISEASE." Alzheimer's & Dementia 10 (July 2014): P547. http://dx.doi.org/10.1016/j.jalz.2014.05.881.

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Peralta, Gabriela P., Joan Forns, Manuela García de la Hera, Llúcia González, Mònica Guxens, Mónica López-Vicente, Jordi Sunyer, and Judith Garcia-Aymerich. "Sleeping, TV, Cognitively Stimulating Activities, Physical Activity, and Attention-Deficit Hyperactivity Disorder Symptom Incidence in Children." Journal of Developmental & Behavioral Pediatrics 39, no. 3 (April 2018): 192–99. http://dx.doi.org/10.1097/dbp.0000000000000539.

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Runge, Shannon K., Brent J. Small, G. Peggy McFall, and Roger A. Dixon. "APOE Moderates the Association between Lifestyle Activities and Cognitive Performance: Evidence of Genetic Plasticity in Aging." Journal of the International Neuropsychological Society 20, no. 5 (May 2014): 478–86. http://dx.doi.org/10.1017/s1355617714000356.

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AbstractThe current study examined independent and interactive effects between Apolipoprotein E (APOE) genotype and two types of cognitively-stimulating lifestyle activities (CSLA)—integrated information processing (CSLA-II) and novel information processing (CSLA-NI)—on concurrent and longitudinal changes in cognition. Three-wave data across 6 years of follow-up from the Victoria Longitudinal Study (n=278; ages 55–94) and linear mixed model analyses were used to characterize the effects of APOE genotype and participation in CSLA-II and CSLA-NI in four cognitive domains. Significant CSLA effects on cognition were observed. More frequent participation in challenging activities (i.e., CSLA-NI) was associated with higher baseline scores on word recall, fact recall, vocabulary and verbal fluency. Conversely, higher participation in less cognitively-challenging activities (i.e., CSLA-II) was associated with lower scores on fact recall and verbal fluency. No longitudinal CSLA-cognition effects were found. Two significant genetic effects were observed. First, APOE moderated CSLA-II and CSLA-NI associations with baseline verbal fluency and fact recall scores. Second, APOE non-ɛ4 carriers’ baseline performance were more likely to be moderated by CSLA participation, compared to APOE-ɛ4 carriers. Our findings suggest APOE may be a “plasticity” gene that makes individuals more or less amenable to the influence of protective factors such as CSLA. (JINS, 2014,20, 1–9)
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Sharifian, Neika, A. Zarina Kraal, Afsara B. Zaheed, Ketlyne Sol, and Laura B. Zahodne. "Longitudinal Associations Between Contact Frequency with Friends and with Family, Activity Engagement, and Cognitive Functioning." Journal of the International Neuropsychological Society 26, no. 8 (March 23, 2020): 815–24. http://dx.doi.org/10.1017/s1355617720000259.

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AbstractObjectives:Social engagement may be an important protective resource for cognitive aging. Some evidence suggests that time spent with friends may be more beneficial for cognition than time spent with family. Because maintaining friendships has been demonstrated to require more active maintenance and engagement in shared activities, activity engagement may be one underlying pathway that explains the distinct associations between contact frequency with friends versus family and cognition.Methods:Using two waves of data from the national survey of Midlife in the United States (n = 3707, Mage = 55.80, 51% female at baseline), we examined longitudinal associations between contact frequency with friends and family, activity engagement (cognitive and physical activities), and cognition (episodic memory and executive functioning) to determine whether activity engagement mediates the relationship between contact frequency and cognition.Results:The longitudinal mediation model revealed that more frequent contact with friends, but not family, was associated with greater concurrent engagement in physical and cognitive activities, which were both associated with better episodic memory and executive functioning.Conclusion:These findings suggest that time spent with friends may promote both cognitively and physically stimulating activities that could help to preserve not only these social relationships but also cognitive functioning.
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Larson, Jordan, Jennifer Oh, Rebecca Koscik, Maritza Dowling, Catherine Gallagher, Cynthia Carlsson, Howard Rowley, et al. "IC-01-03: PARTICIPATION IN COGNITIVELY STIMULATING ACTIVITIES IS ASSOCIATED WITH BRAIN STRUCTURE AND COGNITIVE FUNCTION IN PRECLINICAL ALZHEIMER'S DISEASE." Alzheimer's & Dementia 10 (July 2014): P2. http://dx.doi.org/10.1016/j.jalz.2014.04.020.

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39

Cuevas, Heather E., Alexa K. Stuifbergen, and Catherine Ward. "Participant Perspectives of Cognitive Rehabilitation for Type 2 Diabetes: Expectations and Impact." Journal of Aging Research 2018 (August 19, 2018): 1–9. http://dx.doi.org/10.1155/2018/6563457.

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Purpose. To describe the experiences of people with type 2 diabetes who have completed a comprehensive cognitive rehabilitation intervention. Method. Nineteen participants with type 2 diabetes enrolled in an 8-week intervention consisting of 4 educational classes to learn strategies to improve cognitive function and an online training program at home to practice cognitively stimulating activities. Two focus groups were conducted as part of a study designed to assess the feasibility of the comprehensive cognitive rehabilitation intervention. Results. Three main themes were identified in the qualitative data: (1) expectations of cognitive change; (2) use of cognitive strategies; and (3) effect on diabetes self-management. Participants shared valuable insight into how their experiences with the intervention changed and how they viewed diabetes. Conclusions. While the participants did not initially tie their cognitive complaints to diabetes, they were able to show how and why they might use cognitive strategies to improve diabetes self-management activities. By adapting those strategies for diabetes, quality of life can improve as well as potentially glycemic control.
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Kolanowski, Ann, Donna Fick, Mark Litaker, Paula Mulhall, Linda Clare, Nikki Hill, Jacqueline Mogle, Malaz Boustani, David Gill, and Andrea Yevchak-Sillner. "Effect of Cognitively Stimulating Activities on Symptom Management of Delirium Superimposed on Dementia: A Randomized Controlled Trial." Journal of the American Geriatrics Society 64, no. 12 (November 12, 2016): 2424–32. http://dx.doi.org/10.1111/jgs.14511.

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41

Hueluer, Gizem, and George W. Rebok. "THE ROLE OF WORK AND RETIREMENT IN COGNITIVE AND BRAIN AGING." Innovation in Aging 3, Supplement_1 (November 2019): S24. http://dx.doi.org/10.1093/geroni/igz038.090.

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Abstract According to the “use it or lose it” hypothesis of cognitive aging, cognitive enrichment and cognitively engaging activities are associated with the maintenance of high levels of cognitive functioning in old age. Similar ideas have been brought forward with respect to characteristics of individuals’ work environment, with more cognitively enriching work demands providing an optimal environment for cognitive development and maintenance. The goal of this research group is to showcase new developments in research on work, retirement and cognitive aging. Hülür et al. examine the role of perceived work environment for cohort differences in trajectories of cognitive change based on 56-year longitudinal data from the Seattle Longitudinal Study. Andel et al. use data from the Swedish Adoption/Twin Study of Aging to examine trajectories of cognitive aging before vs. after retirement with two-slope growth curve models. Zulka et al. conduct a systematic literature review on the association between retirement and cognition and examine the role of factors such as occupational experiences and the cognitive domain studied. Burzynska et al. investigate the relationship between stressful and stimulating occupational exposures and structural brain health and cognition in older age. The discussion by George Rebok will focus on how these findings contribute to our understanding of the role of occupational experiences for cognitive and brain aging and how they can be utilized to promote maintenance of cognitive functioning in old age.
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42

Jung, Seojung, and Karen Siedlecki. "Temporal Relationship Between Activity Engagement and Cognition." Innovation in Aging 4, Supplement_1 (December 1, 2020): 592. http://dx.doi.org/10.1093/geroni/igaa057.1987.

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Abstract Previous studies have shown that activity engagement is related to cognitive function. However, few studies have examined the temporal order between activity engagement and various domains of cognition. Using data from the Virginia Cognitive Aging Project (baseline N =5430, Mage =51.28, SD =18.12), we examined the temporal relationships between engagement in physical and cognitive activity and different cognitive domains (reasoning, spatial visualization, episodic memory, processing speed, vocabulary) after controlling for age, education, self-rated health and depression. Cross-lagged panel analyses indicate that very few of the temporal relationships between activity level and cognition were significant except higher levels of cognitive activity significantly predicted better future processing speed, but not the reverse. Findings suggest the importance of engaging in cognitively stimulating activities, which help adults preserve processing speed over time. This study also highlights the importance of longitudinal design on various domains of cognition to help develop domain-specific interventions.
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43

León, Irene, Juan García-García, and Lola Roldán-Tapia. "Escala de Reserva Cognitiva y envejecimiento." Anales de Psicología 32, no. 1 (December 25, 2015): 218. http://dx.doi.org/10.6018/analesps.32.1.182331.

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<p>The construct of cognitive reserve attempts to explain why some individuals with brain impairment, and some people during normal ageing, can solve cognitive tasks better than expected. This study aimed to estimate cognitive reserve in a healthy sample of people aged 65 years and over, with special attention to its influence on cognitive performance. For this purpose, it used the Cognitive Reserve Scale (CRS) and a neuropsychological battery that included tests of attention and memory. The results revealed that women obtained higher total CRS raw scores than men. Moreover, the CRS predicted the learning curve, short-term and long-term memory, but not attentional and working memory performance. Thus, the CRS offers a new proxy of cognitive reserve based on cognitively stimulating activities performed by healthy elderly people. Following an active lifestyle throughout life was associated with better intellectual performance and positive effects on relevant aspects of quality of life.</p>
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Block, Laura, Megan Peck, and Andrea Gilmore-Bykovskyi. "Design and Preliminary Evaluation of a Community-Based Brain Health Promotion and Wellness Program." Innovation in Aging 4, Supplement_1 (December 1, 2020): 224–25. http://dx.doi.org/10.1093/geroni/igaa057.724.

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Abstract Recommendations for risk reduction of dementia and cognitive decline emphasize addressing modifiable risk factors including physical activity, cognitive stimulation, and socialization. However, existing resources and programs to promote brain health through multifaceted risk factor reduction are often costly, challenging to individualize, and limited in their delivery format, narrowing their accessibility among older adults. To address community identified needs for brain health promotion resources, we applied a user-centered design approach to develop, implement, and evaluate feasibility/acceptability of a community-based brain health promotion program: Strength & Resilience Brain Health and Wellness Program. Design requirements were specified through ongoing end-user feedback via structured and open-ended surveys, group dialogue, and facilitator memoing which informed needed iterative refinements of program components. The resultant program incorporates information about brain health/dementia prevention, physical exercise, and cognitively-stimulating activities targeting attention, focus, problem solving, and communication. Integrated across components are deliberate adaptations for physical/cognitive abilities and activities to facilitate group cohesion and reduce stigma. Across two 10-week offerings, we found the program to be feasible as demonstrated through high enrollment (N=44) and retention (75%). A quarter of participants self-disclosed a dementia diagnosis in baseline surveys. Participants rated program components as acceptable, and perceived positive influences on target risk factors particularly social isolation, sense of self-worth, and cognitive stimulation. The current study provides a platform for a feasible and scalable group, community-based brain health promotion program, and suggests participant-centered outcomes extend beyond cognitive domains. More rigorous evaluation of the program is needed to evaluate fidelity across components and standardized outcomes.
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Cadar, Dorina, Celine De Looze, and Christine McGarrigle. "Cardiovascular Health, Functional Disability, and Leisure Activities Profiles in Relation to Mental Aging." Innovation in Aging 4, Supplement_1 (December 1, 2020): 663. http://dx.doi.org/10.1093/geroni/igaa057.2292.

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Abstract We investigated cardiovascular health, functional disability and leisure activities profiles independently and in relation to cognitive decline and dementia in high and low-medium income countries using data from the English Longitudinal Study of Ageing, Irish Longitudinal Study on Ageing and Brazilian Bambui Cohort Study of Aging. Functional loss among older Brazilians has shown a hierarchical sequence over the 15-year follow-up, with the highest incidence in functional disability reported for dressing, followed by getting out of bed, bathing/showering, walking across a room, using the toilet and eating (de Oliveira). Using the Life’s Simple 7, an ideal cardiovascular health scoring system evaluating the muscular strength, mobility and physiological stress, we showed a reliable prediction of cognitive trajectories in a representative sample of Irish individuals (De Looze). Within the same cohort, we report discrepancies between men and women in functional decline driven by domestic tasks, rather than determining differential cognitive trajectories (McGarrigle). In an English representative sample, we found that participants with an increasing number of functional impairments over almost a decade were more likely to be classified with subsequent dementia compared with those with no impairments and this may imply a more comprehensive ascertainment during the prodromal stage of dementia (Cadar). In contrast, a reduced risk of dementia was found for individuals with higher levels of engagement in cognitively stimulating activities, that may preserve cognitive reserve until later in life (Almeida). Identifying factors that influence cognitive aging and dementia risk in a multifactorial perspective is critical toward developing adequate intervention and treatment.
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46

Bogunovic, Blanka, and Nada Polovina. "Educational-material context of the family and students’ attitudes towards schooling." Zbornik Instituta za pedagoska istrazivanja 39, no. 1 (2007): 99–114. http://dx.doi.org/10.2298/zipi0701099b.

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The impact of the family environment, the mode and the quality of parental stimulation may have a decisive role in the student?s capacity development and realization of given capabilities, and affects particularly the level and the quality of his/her academic attainment. A student?s academic attainment is conditioned by educational aspirations formed in a dynamic interaction with stimulating aspects of the family context. The aims of our study were: to examine the students? attitudes towards schooling, and to obtain answers to the question: which stimulating aspects of family context are the most predictable for the development of educational aspirations, i.e. attitudes towards school and gaining knowledge, educational interests and plans for further education. The sample comprised 1.464 eighth-grade students, aged 15, from 34 primary schools in Serbia. The data were collected by the use of questionnaires filled in by the students and school principals. The results indicate a trend of interrelatedness of cognitively and educationally favorable conditions within the family and positive attitudes towards school, attainment, high aspirations and cognitive and intellectual interests for out-of-school activities. It can be concluded that family stimulation is the resultant of the influence of cultural and educational profile of the family and active parental attitudes regarding education and attainment of their children. The findings could have practical implications in the domain of parents/school cooperation, not only in order to increase the awareness of the importance of active participation of both parties, but also to provide useful guidelines for developing optimal contents and procedures. .
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Wilson, Robert S., Tianhao Wang, Lei Yu, Francine Grodstein, David A. Bennett, and Patricia A. Boyle. "Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia." Neurology 97, no. 9 (July 14, 2021): e922-e929. http://dx.doi.org/10.1212/wnl.0000000000012388.

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ObjectiveTo test the hypothesis that higher level of cognitive activity predicts older age at dementia onset in Alzheimer disease (AD) dementia.MethodsAs part of a longitudinal cohort study, 1,903 older persons without dementia at enrollment reported their frequency of participation in cognitively stimulating activities. They had annual clinical evaluations to diagnose dementia and AD, and the deceased underwent neuropathologic examination. In analyses, we assessed the relation of baseline cognitive activity to age at diagnosis of incident AD dementia and to postmortem markers of AD and other dementias.ResultsDuring a mean of 6.8 years of follow-up, 457 individuals were diagnosed with incident AD at a mean age of 88.6 (SD 6.4, range 64.1–106.5) years. In an extended accelerated failure time model, higher level of baseline cognitive activity (mean 3.2, SD 0.7) was associated with older age at AD dementia onset (estimate 0.026; 95% confidence interval 0.013–0.039). Low cognitive activity (score 2.1, 10th percentile) was associated with a mean onset age of 88.6 years compared to a mean onset age of 93.6 years associated with high cognitive activity (score 4.0, 90th percentile). Results were comparable in subsequent analyses that adjusted for potentially confounding factors. In 695 participants who died and underwent a neuropathologic examination, cognitive activity was unrelated to postmortem markers of AD and other dementias.ConclusionA cognitively active lifestyle in old age may delay the onset of dementia in AD by as much as 5 years.
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Ducharme-Laliberté, Gabriel, Samira Mellah, Benjamin Boller, and Sylvie Belleville. "[P2-579]: NEUROFUNCTIONAL ACTIVATION ASSOCIATED WITH EARLY AND LIFELONG COGNITIVELY STIMULATING ACTIVITIES MODERATES WORKING MEMORY DIFFERENCES IN NORMAL AGING." Alzheimer's & Dementia 13, no. 7S_Part_17 (July 2017): P868—P869. http://dx.doi.org/10.1016/j.jalz.2017.06.1238.

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Tesky, Valentina A., Winfried Banzer, and Johannes Pantel. "P1-007: The AKTIVA-study: Trend analyses of an intervention program to enhance cognitively stimulating activities in older adults." Alzheimer's & Dementia 6 (July 2010): S175. http://dx.doi.org/10.1016/j.jalz.2010.05.554.

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50

Jin, Yinzi, Mingxia Jing, and Xiaochen Ma. "Effects of Digital Device Ownership on Cognitive Decline in a Middle-Aged and Elderly Population: Longitudinal Observational Study." Journal of Medical Internet Research 21, no. 7 (July 29, 2019): e14210. http://dx.doi.org/10.2196/14210.

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Background Cognitive decline is a major risk factor for disability and death and may serve as a precursor of dementia. Digital devices can provide a platform of cognitively stimulating activities which might help to slow cognitive decline during the process of normal aging. Objective This longitudinal study aimed to examine the independent protective factors of desktop and cellphone ownership against cognitive decline in mid-life and older adulthood and to examine the combined effect of desktop and cellphone ownership on the same outcome. Methods Data was obtained from a China Health and Retirement Longitudinal Studies (CHARLS) cohort made up of 13,457 community-dwelling adults aged 45 years or above in 2011-2012. They were followed for 4 years, with baseline measurements taken as well as 2 two-year follow-up visits. Cognitive function was tested during the baseline test and follow-up visits. A global cognition z-score was calculated based on two domains: word recall and mental intactness. The key independent variables were defined as: whether one had desktops with internet connection at home and whether one had a cellphone. An additional categorical variable of three values was constructed as: 0 (no desktop or cellphone), 1 (desktop or cellphone alone), and 2 (desktop and cellphone both). Mixed-effects regression was adjusted for demographic and health behavior as well as health condition risk factors. Results Adjusted for demographic and health behavior as well as health condition risk factors, desktop and cellphone ownership were independently associated with subsequent decreased cognitive decline over the four-year period. Participants without a desktop at home had an adjusted cognitive decline of –0.16 standard deviations (95% CI –0.18 to –0.15), while participants with a desktop at home had an adjusted cognitive decline of –0.10 standard deviations (95% CI –0.14 to –0.07; difference of –0.06 standard deviations; P=.003). A similar pattern of significantly protective association of 0.06 standard deviations (95% CI 0.03-0.10; P<.001) between cellphone ownership and cognitive function was observed over the four-year period. Additionally, a larger longitudinal protective association on cognitive decline was observed among those with both of the digital devices, although the 95% CIs for the coefficients overlapped with those with a single digital device alone. Conclusions Findings from this study underscored the importance of digital devices as platforms for cognitively stimulating activities to delay cognitive decline. Future studies focusing on use of digital devices are warranted to investigate their longitudinal protective factors against cognitive decline at mid- and later life.
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