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Dissertations / Theses on the topic 'Coke drum'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Hu, Yuhua Ph D. Massachusetts Institute of Technology. "pH-sensitive core-shell nanoparticles for intracellular drug delivery." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/42942.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2008.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Vita.<br>Includes bibliographical references (p. 193-208).<br>Therapeutics such as proteins, DNA, or siRNA, can only exert their function in the cell cytosol or nucleus. However, most of them are cell membrane impermeable molecules that can only be taken up by cells via endocytosis or phagocytosis. Such drug molecules are thus confined in endolysosomes

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2

Sun, Qian. "Aqueous core colloidosomes with a metal shell." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/284921.

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Colloidosomes are microcapsules whose shells consist of colloid particles, which are coagulated by a stabiliser or fused by sintering. In recent years, they have attracted considerable attention because of their potential applications in a range of industries, such as food, bioreactors and medicine. However, traditional particulate polymer shell colloidosomes leak low molecular weight encapsulated materials due to their intrinsic shell permeability, and this problem will limit their applications in pharmaceutical industries. In this thesis, we report aqueous core colloidosomes coated with a si

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3

Panduwawala, Tharindi. "Natural product guided antibacterial drug discovery : tetramates as core scaffolds." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:b507ca4d-ef35-4928-90a2-0a3f774a4ed2.

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This thesis describes the synthesis and biological evaluation of a library of compounds containing the tetramic acid core in search of novel antibacterial drug candidates. Chapter 1 discusses the need for new antibiotics due to the emergence of virulent bacterial strains resistant to clinically available drugs and the hiatus in the discovery of new replacement antibitoics that has become a global threat to human health. Different platforms for antibacterial drug discovery and the re-emergence of natural products-based approach that has gained importance in the quest for novel antibiotics are d

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4

Steiner, Katrin [Verfasser]. "The influence of drug core properties on drug release from extended release reservoir pellets / Katrin Steiner." Berlin : Freie Universität Berlin, 2011. http://d-nb.info/1025239733/34.

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5

Sethi, Amit. "Digital Rights Management and Code Obfuscation." Thesis, University of Waterloo, 2004. http://hdl.handle.net/10012/1012.

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Digital Rights Management (DRM) involves retaining control over digital information, even after it has been made public. Preventing illegal file sharing on the Internet, which is a topic that has recently received a large amount of media attention, is just one instance where DRM is needed. In this thesis, we attempt to create formal definitions for DRM. Currently, there is a lack of such formal definitions, which is one reason why DRM schemes have achieved little success. We will also examine two DRM schemes that can be cracked easily: Microsoft DRM 2. 0, and the Content Scrambli

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6

Simmons, Travis G. ""Because they made me come" : motivation and outcome in adolescent substance abuse treatment /." Electronic version (PDF), 2005. http://dl.uncw.edu/etd/2005/simmonst/travissimmons.html.

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7

Han, Daewoo. "Core-Sheath Polymer Fibers by Coaxial Electrospinning." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1288975118.

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8

Bhomia, Ruchir. "Studies into solid core drug delivery system using haemoglobin as a model drug and supercritical fluid processing for encapsulation." Thesis, University of Greenwich, 2015. http://gala.gre.ac.uk/14128/.

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The aim of this project was to formulate a solid core drug delivery system for oral delivery of proteins using silica as core material, haemoglobin as model drug and supercritical fluid processing as encapsulation technique. Silica particles of different morphology were used as a carrier material for protein immobilisation and fatty acids coating was performed using supercritical carbon dioxide (CO2) as a processing media. The melting behaviour of saturated fatty acids (lauric, myristic, palmitic and stearic acid) and pluronics (F-38, F-68, F-77, F-127 and F-108) were studied under pressurised

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9

Stefani, Stefano [Verfasser]. "Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems / Stefano Stefani." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1104733854/34.

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10

Ranjan, Ashish. "Development of core-shell nanostructure encapsulating gentamicin as efficient drug delivery system against intracellular Salmonella." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/29082.

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Intracellular pathogens like <i>Salmonella</i> have developed various mechanisms to evade host defenses, and they can establish infections. Treatment and eradication are difficult due to our inability in achieving the optimum concentrations of cell-impermeable aminoglycosides like gentamicin within these cells. In this dissertation, we hypothesize that developing a novel core-shell methodology for incorporating high amounts of gentamicin into the cores with either hydrophilic or amphiphilic shell will be more effective than the free gentamicin in clearing intracellular <i>Salmonella</i> infect

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11

Bergendahl, Veit. "Studying sigma-core binding of bacterial RNA polymerase by LRET biochemistry and drug discovery /." [S.l.] : [s.n.], 2003. http://archiv.ub.uni-marburg.de/diss/z2003/0061/.

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12

Hameed, Fazal [Verfasser], and J. [Akademischer Betreuer] Henkel. "DRAM Aware Last-Level-Cache Policies for Multi-core Systems / Fazal Hameed. Betreuer: J. Henkel." Karlsruhe : KIT-Bibliothek, 2015. http://d-nb.info/1077251165/34.

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13

Trivedi, Vivek. "The preparation of solid core drug delivery system (SCDDS) via supercritical processing of fatty acids." Thesis, University of Greenwich, 2009. http://gala.gre.ac.uk/8113/.

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The aim of this study is to develop a novel drug delivery system for biologics i.e. proteins and peptides using a solid core drug delivery system (SCDDS). Both, 0.5 μm and 1.0 μm silica particles were used as a model core material and were coated with different ratios of fatty acid. A proportional increase in particle size was observed with increasing ratio of fatty acid in the formulation. Coating of silica particles with smaller chain fatty acids (lauric and myristic acid) resulted in a higher increase in particle size compared to the longer chain fatty acids i.e. palmitic acid and stearic a

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14

Pischon, Jeanette Hannah Charlotte [Verfasser]. "Core-Multishell-Nanocarrier for Topical Drug Delivery in a Psoriasis Mouse Model / Jeanette Hannah Charlotte Pischon." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1176632183/34.

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15

Egodawatte, Shani Nirasha. "Environmental and biomedical applications of iron oxide/ mesoporous silica core-shell nanocomposites." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/5462.

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Mesoporous silica has shown great potential as an adsorbent for environmental contaminants and as a host for imaging and therapeutic agents. Mesoporous silica materials have a high surface area, tunable pore sizes and well defined surface properties which are governed by the surface hydroxyl groups. Surface modification of the mesoporous silica can tailor the adsorption properties for a specific metal ion or a small drug molecule by providing better sites for chelation or electrostatic interactions. Iron oxide / mesoporous silica core shell materials couple the favorable properties of both the

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16

Yeh, Hsi-wei. "Investigation of Polymeric Composites for Controlled Drug Release." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4971.

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The Electrospray (ES) technique is a promising particle generation method for drug delivery due to its capabilities of producing monodisperse PLGA composite particles with unique configurations and high drug encapsulation efficiency. In the dissertation work, the coaxial dual capillary ES was used to generate drug-loaded core-shell PLGA particles to study the effects of particle filling materials, drug loading locations and particle shell thicknesses on the resultant in vitro release behaviors of the hydrophilic and/ or hydrophobic model drugs. Through release profile characterization of drug-

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17

Li, Yan [Verfasser]. "Robust Design of DRAM Core Circuits : Yield Estimation and Analysis by A Statistical Design Approach / Yan Li." Aachen : Shaker, 2011. http://d-nb.info/1080764976/34.

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18

Rheiner, Steven. "EFFECTS OF CORE AND SHELL MODIFICATION TO TETHERED NANOASSEMBLIES ON SIRNA THERAPY." UKnowledge, 2017. http://uknowledge.uky.edu/pharmacy_etds/73.

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siRNA therapy is an emerging technique that reduces protein expression in cells by degrading their mRNAs via the RNA interference pathway (RNAi). Diseases such as cancer often proliferate due to increased protein expression and siRNA therapy offers a new method of treatment for those diseases. Although siRNA therapy has shown success in vitro, it often fails in vivo due to instability in the blood stream. To overcome this limitation, delivery vehicles are necessary for successful transfection of siRNA into target cells and cationic polymers have been widely studied for this purpose. However, c

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19

Tobaldini, Renata Teixeira de Castro. "A desvinculação de recursos da união - DRU e o financiamento da seguridade social brasileira." Universidade Estadual de Londrina. Centro de Estudos Sociais Aplicados. Programa de Pós-Graduação em Serviço Social e Política Social, 2012. http://www.bibliotecadigital.uel.br/document/?code=vtls000172867.

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A pesquisa que ora se apresenta tem como tema a Desvinculação de Recursos da União e sua relação com o financiamento da Seguridade Social brasileira. O objetivo é discutir/analisar o uso deste mecanismo pelo Estado brasileiro no contexto atual de retorno à ortodoxia para recompor as taxas de lucro do capital, apresentando os impactos deste mecanismo para o financiamento da seguridade social brasileira, afetando a garantia de direitos fundamentais dos cidadãos. Por meio de uma pesquisa bibliográfica levantamos o conceito, o histórico, as principais discussões da atualidade e o montante de recur

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20

Dixon, Jeffrey James, and Alistair Saint McLean. "Technical modification within the healthcare industry: improving both the efficacy of the National Drug Code carrier and the accessibility of electronic health records to reduce adverse drug events." Monterey, California: Naval Postgraduate School, 2013. http://hdl.handle.net/10945/34705.

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Approved for public release; distribution is unlimited<br>The main focus of this thesis is to present the idea that QR codes could contribute to a reduction in adverse drug events (ADEs) by increasing the efficacy of the national drug code and storing an electronic health record. This research examines a change in drug coding technology that will decrease the number of ADEs by empowering patients to be more proactive in tracking their current prescription and over-the-counter drugs, and the ADEs associated with them. The main objectives of this research are to demonstrate the benefits of repla

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21

Sharma, Khushboo. "Synthesis and Characterization of a Novel Amphiphilic Core-Corona Hyperbranched Polymer, composed of EHMO and EHMOpeg, for drug delivery." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2207.

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A novel amphiphilic core-corona hyperbranched polymer, composed of 3-ethyl-3-(hydroxylmethyl) oxetane (EHMO) and PEGylated EHMO (EHMOPEG), was synthesized through cationic ring opening polymerization. Nuclear Magnetic Resonance spectroscopy (NMR), Dynamic Light Scattering (DLS), and Fourier Transform Infrared spectroscopy (FTIR) were used to characterize the polymer structure and degree of branching. It was found that the degree of branching (DOB) of the polymer was affected by the weight % ratios of EHMO/EHMOPEG used in polymerization. As the weight % ratio of EHMO/ EHMOPEG decreased, the DOB

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22

Cameros, Brian (Brian Leigh) 1971. "Crystal structure of a mutation in the HIV gp41 core : effect on a deep cavity and implication for drug development." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/85354.

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23

Rumetshofer, Anna. "Playing the European Postal Code Lottery? : Analysis of Time to Market of new Drugs on the European Market." Thesis, Uppsala universitet, Nationalekonomiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-391498.

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This thesis seeks to investigate the vastly varying time to market of newly approved drugs across Europe. Firtsly, I use a country fixed effects model on data of newly approved drugs from 2014 to 2017 from 18 European countries. I investigate the correlations between medication specific characteristics and the launch time and find that drugs intended to treat HIV, rheumatism or hepatitis are correlated with a faster launch time. Orphan drugs, though they represent a third of the dataset are found to be insignificantly correlated with time to market. Using a drug fixed effects model, I research

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24

Casasola, Raffaella. "Electrospinning of poly (lactic) acid for biomedical applications : analysis of solution properties and process parameters, drug encapsulation and release." Thesis, Loughborough University, 2016. https://dspace.lboro.ac.uk/2134/22949.

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Electrospinning or electrostatic fibre spinning employs electrostatic force to draw fibres from a liquid, either a polymeric solution or a polymer melt in the form of a charged jet. The jet solidifies and is deposited on a collector in the form of a non-woven fibrous mat. Electrospun fibres have diameters between several nanometres to a few microns, which is one of the main advantages of the process, as materials at the nanoscale have shown great potential in a wide range of healthcare and energy applications. The initial selection of solvents to dissolve the polymer for production of electros

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25

Chamradová, Ivana. "Polymerní materiály pro řízenou administraci léčiv a řízené uvolňování aktivních látek." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2015. http://www.nusl.cz/ntk/nusl-233407.

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Literární rešerše předložené dizertační práce shrnuje poznatky jak o současně používaných biomateriálech, tak i o tzv. „chytrých“ biomedicínských materiálech mezi které patří termocitlivé kopolymery. Mezi tyto kopolymery, jejichž vodné roztoky gelují při teplotě lidského těla (37 °C), řadíme amfifilní triblokové kopolymery skládající se z hydrofobního laktidu, glykolidu a hydrofilního polyethylen glykolu (PLGA PEG PLGA). Komerčně dostupné termocitlivé kopolymery známé pod názvem ReGel or OncoGel jsou v současné době využívány jako injekčně aplikovatelné nosiče s postupným uvolňováním léčiv,

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26

Profit, Deborah J. "Educating Adolescents and Young Adults on Clinical Research and the Drug-Development Process| Can Public and Private Leaders Come Together to Deliver Greater Good?" Thesis, Franklin Pierce University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3640151.

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<p> The development of new medical treatments for patients is limited by the challenges of recruiting clinical-research participants. In the United States, the Food and Drug Administration regulates the multidimensional approval process for new drugs, biologics, and medical devices to ensure consumer safety. The regulatory approval processes includes complex clinical trials that necessitate either healthy volunteers or patients who are willing to participate. The low enrollment rates of volunteers and patients willing to participate in clinical trials are resulting in significant delays in bri

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27

Daniel, A. Gerard. "Zinc Environment in Proteins: The Flexible and Reactive Core of HIV-1 NCp7 and The Inhibitory Site of Caspase-3." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/3263.

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Zinc is an essential cofactor of several proteins. The roles of zinc in these proteins are classified as catalytic, structural or regulatory. Zinc present in structural sites is considered to be a chemically inert, static structural element. On the contrary, previous studies on a C2H2 type zinc finger model compound and the C3H type HIV-1 NCp7 C-terminal zinc knuckle have shown that zinc at these sites can undergo coordination sphere expansion under the influence of a Pt based electrophile. The pentacoordination observed around zinc in these experiments raises an important question: are the st

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28

Khan, Ikram Ullah. "Microfluidic-assisted synthesis and release properties of multi-domain polymer microparticles drug carriers." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAF042/document.

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Les caractéristiques et les propriétés de libération de microparticules chargées de médicament dépendent de la nature des matériaux employés, des propriétés physicochimiques des microparticules, du choix de la méthode de production, et enfin des propriétés des molécules encapsulées. A l'inverse de la plupart des méthodes conventionnelles, les méthodes microfluidiques présentent l’avantage de bien mieux contrôler la génération de gouttelettes, leur taille et leur distribution de tailles. Ainsi des dispositifs microfluidiques à base de capillaires ont été développés pour obtenir des microbilles

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29

Garmendia, Craig A. "Patterns of Regularity Noncompliance Identified by the U.S. Food and Drug Administration and Their Effects on Meta-analyses." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3920.

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The objective of this study was to determine the patterns of regulatory noncompliance, as identified by the U.S. Food and Drug Administration (FDA), and their effects on meta-analyses. In order to achieve these objective, three studies were undertaken: analysis of citations issued by FDA Investigators at the conclusion of an inspection; analysis of regulatory actions taken by the FDA towards clinical researchers based on the observations cited by FDA Investigators; and sensitivity analysis of meta-analyses based on the Agency’s determination of research misconduct, primarily the falsification

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30

Reichel, Derek Alexander. "HALO- AND SOLVATO-FLUOROCHROMIC POLYMER NANOASSEMBLIES FOR CANCER THERANOSTICS." UKnowledge, 2017. http://uknowledge.uky.edu/pharmacy_etds/74.

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Theranostics is an emerging treatment approach that combines diagnostics with therapy in order to personalize treatment regimens for individual patients and decrease cancer mortality. Previously, nanoparticles entrapping conventional fluorescent dyes were developed for cancer theranostics, but fluorescent nanoparticles did not allow clinicians to significantly improve cancer treatments. The use of fluorescent dyes that are sensitive to solvent acidity (halo-fluorochromism) and polarity (solvato-fluorochromism) may overcome the limitations of fluorescent nanoparticles and improve cancer therapy

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31

Cope, Zackary A., Kimberly N. Huggins, A. Brianna Sheppard, Daniel M. Noel, David S. Roane, and Russell W. Brown. "Neonatal Quinpirole Treatment Enhances Locomotor Activation and Dopamine Release in the Nucleus Accumbens Core in Response to Amphetamine Treatment in Adulthood." Digital Commons @ East Tennessee State University, 2010. https://doi.org/10.1002/syn.20729.

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Neonatal quinpirole treatment to rats produces long-term increases in D(2) receptor sensitivity that persists throughout the animal's lifetime, a phenomenon referred to as D(2) priming. Male and female Sprague-dawley rats were administered quinpirole (1 mg kg(-1)) or saline from postnatal days (P)1-11. At P60, all animals were given an injection of quinpirole (100 microg kg(-1)), and results showed that rats neonatally treated with quinpirole demonstrated enhanced yawning in response to quinprole, verifying D(2) receptor priming because yawning is a D(2) receptor mediated event. Beginning 1-3

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32

Zhuk, Mikalai. "Nanostructured granules for controlled delivery of dexamethasone." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/14181.

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Mestrado em Ciência e Engenharia de Materiais<br>A Drug Delivery System (DDS) may provide the precise transportation of the medical drug inside the patient’s body, directly to the pathological area or alternatively it may be also locally administrated. Once at the site of interest, the ideal DDS is expected to release the drug in a sustained manner according to the specific needs of the patient. As compared to other routes of drug administration, an appropriately designed DDS which active components are conveniently targeted should also ensure the desired in situ treatment without harmful effe

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33

Benin, Bogdan Markovich. "Synthesis and Characterization of Novel Gold-Based Nanoparticulate Chemotherapeutic Agents." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1461088605.

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34

Macmillan, Stanley. "Constraints management in a continuous-batch process." Diss., Pretoria : [s.n.], 2004. http://upetd.up.ac.za/thesis/available/etd-08082004-070610.

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35

Romo, Arango Sebastian A. "Low-Cycle Fatigue of Low-Alloy Steel Welded Joints." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1573054310351145.

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36

Costamagna, Federica. "Colloidal stability, intracellular fate and toxicology of drug nanocarriers - Application to polymerized micelles and organometallic nanogels Nanotoxicology at the particle/micelle frontier: influence of core-polymerization on the intracellular distribution, cytotoxicity and genotoxicity of polydiacetylene micelles." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASS128.

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Une compréhension approfondie de la stabilité colloïdale est nécessaire pour concevoir des nanoparticules pour la vectorisation de molécules actives. En particulier, prévoir le comportement in vivo des particules (désagrégation ou agrégation) est fondamental pour prédire l’efficacité et la toxicité des nanoformulations. Les objectifs de cette thèse concernaient (1) l’amélioration de la stabilité colloïdale en conditions physiologiques et (2) l’étude in vitro du comportement biologique de deux types de nanovecteurs : nanogels à base de chitosane-fer et micelles de polydiacétylène<br>A thorough

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37

Battaglia, Dax C. "An activity-based cost analysis of the Substance Abuse Counseling Center, Marine Corps Base Hawaii." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2003. http://library.nps.navy.mil/uhtbin/hyperion-image/03Mar%5FBattaglia.pdf.

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Andrade, Diego Fontana de. "Nanocápsulas de núcleo lipídico : estudos de penetração cutânea e proposição de estratégias para a avaliação da liberação in vitro." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/94616.

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Neste trabalho foi avaliada a permeação/penetração cutânea in vitro (pele suína) de propionato de clobetasol nanoencapsulado incorporado em um semissólido, empregando células de difusão de Franz. A nanoencapsulação foi capaz de reduzir a quantidade de fármaco que penetra nas camadas da pele (estrato córneo, epiderme e derme) sem alterar a forma (distribuição percentual) como o propionato de clobetasol se distribui. A adequabilidade de diferentes membranas sintéticas (acetato de celulose, policarbonato e membrana de diálise) para a avaliação da liberação in vitro, empregando células de difusão

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39

Caba, Beth Lynn. "Solution and Adsorption Characterization of Novel Water-Soluble Ionic Block Copolymers for Stabilization of Magnetite Nanoparticles." Diss., Virginia Tech, 2007. http://hdl.handle.net/10919/27614.

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There is a need for multifunctional polymer-particle complexes for use in biomedical applications such as for drug delivery or as MRI contrast agents where composition and stability are essential for the complexes to function. This work outlines a general methodology for rationally designing complexes stabilized with polymer brush layers using adapted star polymer models for brush extension and pair potential. Block copolymer micelles were first utilized for experimental validation by using the brush extension model to predict the size and the interaction model to predict the second virial c

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40

Bulteau, François. "Ciblage in vivo des tumeurs via l'antigène Tn : Développement d'un cluster de Macrophage Galactose Lectine Human Macrophage Galactose-Type Lectin (MGL) Recognizes the Outer Core of Escherichia coli Lipooligosaccharide." Thesis, Université Grenoble Alpes, 2020. http://www.theses.fr/2020GRALV048.

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L’ensemble des cellules, qu’elles soient procaryotes ou eucaryotes, est doté d’une couche de glycosylation externe riche et diversifiée, composant la face dominante immédiate en relation à leur environnement. Elles résultent de processus enzymatiques complexes liant les sucres entre eux et sur des protéines ou lipides. Des variations du « glycome » peuvent apparaître dans certaines pathologies. Les cancers sont les pathologies les plus fréquentes présentant des anomalies de ces glycosylations. Ces altérations sont quasi systématiques à la surface des cellules cancéreuses. Parmi celles-ci, l’an

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41

Kaufman, Amanda Christine. "A System of Aesthetics: Emily Dickinson's Civil War Poetry." University of Toledo Honors Theses / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=uthonors1292535978.

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42

Spáčil, Tomáš. "Bicí automat pro hudebníky." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2014. http://www.nusl.cz/ntk/nusl-220353.

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The aim of this work is to create a functional prototype of a drum machine with sound generating using a microcontroller. Introduction is devoted to general drum machine and an analysis of its parts, principle and basic modes of operation. The following chapter deals with the principle of digital signal processing and sound generation using a microcontroller. Part of this chapter is focused on mixing using compression methods. The core of this work is to design my own block structure and overall scheme of the drum machine with a description of the parts. Followed by analysis and implementation

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Ménard, Mathilde. "Synthèse de nanoparticules hybrides de type coeur-coquille à visées théranostiques." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAE050/document.

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Le but de ce travail de thèse a été de synthétiser de nouveaux nano-objets pour le diagnostic et le traitement du cancer. Ainsi, nous avons développé des nanoparticules hybrides constituées d'un noyau inorganique recouvert d'une couche organique de sérum albumine humaine (HSA). Le noyau inorganique est un composite constitué d'un cœur d'oxyde de fer (IO) et d'une coquille de silice mésoporeuse (MS). L’IO permet, grâce à ses propriétés magnétiques, le diagnostic par imagerie par résonance magnétique (IRM) et la thérapie par hyperthermie magnétique (HM), tandis que les porosités de la MS permett

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Almeida, Silvia Helena Oliveira de. "Incorporação de novas tecnologias de informação em um sistema de distribuição de medicamentos : avaliação quanto ao aumento da segurança de pacientes." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/62092.

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Introdução: A área Hospitalar vem sofrendo constantes mudanças organizacionais devido à introdução de novas tecnologias que incentivam a segurança do paciente. Aquelas aplicadas à distribuição de medicamentos podem abreviar o número de erros de distribuição, obter em tempo real um elevado nível de informação sobre todo processo e gerir melhor o tempo do profissional farmacêutico, de forma a aumentar a intervenção deste na prevenção de erros de medicações e consequentemente, os cuidados farmacêuticos ao doente internado. Objetivos: Avaliar o impacto da implantação de novas tecnologias que visam

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Jamal, Al Dine Enaam. "Synthèse et caractérisation des nanoparticules intelligentes." Thesis, Université de Lorraine, 2017. http://www.theses.fr/2017LORR0054/document.

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L’un des enjeux majeurs en nanomédecine est de développer des systèmes capables à la fois de permettre un diagnostic efficace et également de servir de plateforme thérapeutique pour combattre les infections et les neuro-dégénérescences. Dans cette optique, et afin d’améliorer la détection de tumeurs, des agents de contraste ont été développés dans le but d’augmenter le rapport signal sur bruit. Parmi ces agents, les nanoparticules (NPs) d’oxyde de fer superparamagnétiques (SPIOs) et les quantum dots (QDs) sont des candidats idéaux et ont reçu une grande attention depuis une vingtaine d’années.

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Chen, Jie. "Experimental study of elastoplastic mechanical properties of coke drum materials." Master's thesis, 2010. http://hdl.handle.net/10048/1013.

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Thesis (M. Sc.)--University of Alberta, 2010.<br>Title from pdf file main screen (viewed on July 7, 2010). A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Master of Science, [Department of] Mechanical Engineering, University of Alberta. Includes bibliographical references.

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Vakilalroayaei, Hessam. "Dynamic Behaviour of Coke Drums PSVs During Blocked Outlet Condition." Thesis, 2009. http://hdl.handle.net/10012/4382.

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The maximum yield taken in an oil refinery can not exceed 70% without including Delayed Coker Unit (DCU) as part of unit operations in the refinery. This implies naturally a big attraction on investing of such a unit for refiners. However, during the past decades, there were few refiners included Coker unit in the refinery, due to the fact of its large capital investment with a high marginal profitability. On the other hand the technologies developed to operate a coker unit, involve a series of process steps that require highly trained and well experienced operators with a state of art of desi

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Lin, Li-Chen, and 林秝楨. "Analysis On Mode of Drug Crime- Taking Drug Market as Core." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/99058236182273041388.

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碩士<br>國立中正大學<br>犯罪防治所<br>96<br>With technology development and information popularization, transportation is getting more and more convenient, which makes drug dealing become a global-level drug market. Therefore, drug problem is also becoming a global crisis. Recent years have seen continuing high criminal rate related with drugs in this country; its popular rate is also on upward trend; the ages of drug users are also becoming younger and younger. Further more, co morbidity rate related with drugs is increasing, such as the rate of AIDS, death and injury caused by the injection of drugs, as

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Zahr, Alisar S. "Solid core-shell drug nanoparticles for therapeutic delivery." 2007. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-1738/index.html.

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Li, Min Jhan, and 李旻展. "Development of Biodegradable Shell-core Structured Microspheres for Drug Delivery." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/4b2awg.

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碩士<br>長庚大學<br>機械工程學系<br>105<br>In this study, electrospraying techniques were used to prepare biodegradable particle carriers. Poly (lactide-co-glycolide), hydrochloride, vancomycin hydrochloride, ceftazidime hydrate, green fluorescent protein, along with different kinds of solvents were used to manufacture the biodegradable drug-eluting microspheres. The diameter of the microspheres of the solid microspheres and the shell-core microspheres prepared by using the optimum processing parameters is about 5 ~ 10 μm. The microspheres of the shell and core structure were confirmed by transmission ele

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