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Journal articles on the topic 'Colloidosomes ; metal shell ; drug delivery'

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1

Liang, Zuozhong, Zhiyuan Yang, Haitao Yuan, et al. "A protein@metal–organic framework nanocomposite for pH-triggered anticancer drug delivery." Dalton Transactions 47, no. 30 (2018): 10223–28. http://dx.doi.org/10.1039/c8dt01789a.

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2

Lu, Liangyu, Mengyu Ma, Chengtao Gao, et al. "Metal Organic Framework@Polysilsesequioxane Core/Shell-Structured Nanoplatform for Drug Delivery." Pharmaceutics 12, no. 2 (2020): 98. http://dx.doi.org/10.3390/pharmaceutics12020098.

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Modern pharmaceutics requires novel drug loading platforms with high drug loading capacity, controlled release, high stability, and good biocompacity. Metal–organic frameworks (MOFs) show promising applications in biomedicine owing to their extraordinarily high surface area, tunable pore size, and adjustable internal surface properties. However, MOFs have low stability due to weak coordinate bonding and limited biocompatibility, limiting their bioapplication. In this study, we fabricated MOFs/polysilsesquioxane (PSQ) nanocomposites and utilized them as drug carriers. Amine-functionalized MOF (
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3

Cong, Hai-Lin, Fei-Fei Jia, Song Wang, Ming-Tao Yu, You-Qing Shen, and Bing Yu. "Core–Shell Upconversion Nanoparticle@Metal–Organic Framework Nanoprobes for Targeting and Drug Delivery." Integrated Ferroelectrics 206, no. 1 (2020): 66–78. http://dx.doi.org/10.1080/10584587.2020.1728627.

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4

Zhao, Huai-Xin, Quan Zou, Shao-Kai Sun, et al. "Theranostic metal–organic framework core–shell composites for magnetic resonance imaging and drug delivery." Chemical Science 7, no. 8 (2016): 5294–301. http://dx.doi.org/10.1039/c6sc01359g.

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A novel multifunctional MOF-based composite with good biocompatibility, high drug loading capacity, sustained drug release and outstanding MR imaging capability was developed through a simple in situ growth procedure for simultaneous drug delivery and magnetic resonance (MR) imaging.
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5

Zhao, Linling, Huarong Liu, Fengwei Wang, and Lai Zeng. "Design of yolk–shell Fe3O4@PMAA composite microspheres for adsorption of metal ions and pH-controlled drug delivery." J. Mater. Chem. A 2, no. 19 (2014): 7065–74. http://dx.doi.org/10.1039/c4ta00976b.

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Yolk–shell structured pH-responsive Fe<sub>3</sub>O<sub>4</sub>@PMAA microspheres have been prepared for adsorption of metal ions and drug delivery by combined sol–gel reaction, emulsion polymerization and selective etching methods accompanying hydrolysis of PMMA shells of core–shell–shell Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@PMMA composite microspheres.
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6

Porcino, Marianna, Ioanna Christodoulou, Mai Dang Le Vuong, Ruxandra Gref, and Charlotte Martineau-Corcos. "New insights on the supramolecular structure of highly porous core–shell drug nanocarriers using solid-state NMR spectroscopy." RSC Advances 9, no. 56 (2019): 32472–75. http://dx.doi.org/10.1039/c9ra07383c.

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7

Cai, Mengru, Gongsen Chen, Liuying Qin, et al. "Metal Organic Frameworks as Drug Targeting Delivery Vehicles in the Treatment of Cancer." Pharmaceutics 12, no. 3 (2020): 232. http://dx.doi.org/10.3390/pharmaceutics12030232.

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In recent years, metal organic frameworks (MOFs) have been widely developed as vehicles for the effective delivery of drugs to tumor tissues. Due to the high loading capacity and excellent biocompatibility of MOFs, they provide an unprecedented opportunity for the treatment of cancer. However, drugs which are commonly used to treat cancer often cause side effects in normal tissue accumulation. Therefore, the strategy of drug targeting delivery based on MOFs has excellent research significance. Here, we introduce several intelligent targeted drug delivery systems based on MOFs and their charact
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8

Klein, Stefanie, Tobias Luchs, Andreas Leng, Luitpold Distel, Winfried Neuhuber, and Andreas Hirsch. "Encapsulation of Hydrophobic Drugs in Shell-by-Shell Coated Nanoparticles for Radio—and Chemotherapy—An In Vitro Study." Bioengineering 7, no. 4 (2020): 126. http://dx.doi.org/10.3390/bioengineering7040126.

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Our research objective was to develop novel drug delivery vehicles consisting of TiO2 and Al2O3 nanoparticles encapsulated by a bilayer shell that allows the reversible embedment of hydrophobic drugs. The first shell is formed by covalent binding of hydrophobic phosphonic acid at the metal oxide surface. The second shell composed of amphiphilic sodium dodecylbenzenesulfonate emerges by self-aggregation driven by hydrophobic interactions between the dodecylbenzene moiety and the hydrophobic first shell. The resulting double layer provides hydrophobic pockets suited for the intake of hydrophobic
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9

Wang, Daolin, Changyong Gao, Chang Zhou, Zhihua Lin, and Qiang He. "Leukocyte Membrane-Coated Liquid Metal Nanoswimmers for Actively Targeted Delivery and Synergistic Chemophotothermal Therapy." Research 2020 (June 24, 2020): 1–10. http://dx.doi.org/10.34133/2020/3676954.

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We report a leukocyte membrane-coated gallium nanoswimmer (LMGNS) capable of ultrasound-propelled motion, antibiofouling, and cancer cell recognition and targeting. The LMGNS consists of a needle-shaped gallium core encapsulating an anticancer drug and a natural leukocyte membrane shell. Under the propulsion of an ultrasound field, LMGNSs could autonomously move in biological media with a speed up to 108.7 μm s−1. The velocity and motion direction of the LMGNSs can be modulated by regulating the frequency and voltage of the applied ultrasound field. Owing to the leukocyte membrane coating, LMG
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10

Lin, Caixue, Keke Sun, Cheng Zhang, et al. "Carbon dots embedded metal organic framework @ chitosan core-shell nanoparticles for vitro dual mode imaging and pH-responsive drug delivery." Microporous and Mesoporous Materials 293 (February 2020): 109775. http://dx.doi.org/10.1016/j.micromeso.2019.109775.

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11

Li, Xue, Marianna Porcino, Jingwen Qiu, Doru Constantin, Charlotte Martineau-Corcos, and Ruxandra Gref. "Doxorubicin-Loaded Metal-Organic Frameworks Nanoparticles with Engineered Cyclodextrin Coatings: Insights on Drug Location by Solid State NMR Spectroscopy." Nanomaterials 11, no. 4 (2021): 945. http://dx.doi.org/10.3390/nano11040945.

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Recently developed, nanoscale metal-organic frameworks (nanoMOFs) functionalized with versatile coatings are drawing special attention in the nanomedicine field. Here we show the preparation of core–shell MIL-100(Al) nanoMOFs for the delivery of the anticancer drug doxorubicin (DOX). DOX was efficiently incorporated in the MOFs and was released in a progressive manner, depending on the initial loading. Besides, the coatings were made of biodegradable γ-cyclodextrin-citrate oligomers (CD-CO) with affinity for both DOX and the MOF cores. DOX was incorporated and released faster due to its affini
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12

Saykova, Diana, Svetlana Saikova, Yuri Mikhlin, Marina Panteleeva, Ruslan Ivantsov, and Elena Belova. "Synthesis and Characterization of Core–Shell Magnetic Nanoparticles NiFe2O4@Au." Metals 10, no. 8 (2020): 1075. http://dx.doi.org/10.3390/met10081075.

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In this study, NiFe2O4@Au core–shell nanoparticles were prepared by the direct reduction of gold on the magnetic surface using amino acid methionine as a reducer and a stabilizing agent simultaneously. The obtained nanoparticles after three steps of gold deposition had an average size of about 120 nm. The analysis of particles was performed by X-ray diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy, and UV-Vis spectroscopy techniques. The results indicate successful synthesis of core–shell particles with the magnetic core, which consists of a few agglomerated nick
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13

Akouibaa, A., A. Derouiche, and H. Redouane. "Numerical study of the effects of polymeric shell on plasmonic resonance of gold nanorods." International Journal of Computational Materials Science and Engineering 03, no. 04 (2014): 1450024. http://dx.doi.org/10.1142/s2047684114500249.

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Gold nanorods (GNRs) have great potential widespread applications in biomedical imaging, drug delivery and photothermal therapy due to unique surface plasmon resonance (SPR) ranging from visible to near infrared (NIR) region, facile synthesis and easy functionalization. The frequency of SPR is not only determined by the nature of the metal, but also by a number of other parameters, such as particle size and shape, the presence of a capping shell on the particle surface, or the dielectric properties of the surrounding medium. In this study, use is made of finite element method (FEM) for the cal
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14

Ali, A., M. A. Ashraf, Q. A. Minhas, Q. A. Naqvi, M. A. Baqir, and P. K. Choudhury. "On the Core-Shell Nanoparticle in Fractional Dimensional Space." Materials 13, no. 10 (2020): 2400. http://dx.doi.org/10.3390/ma13102400.

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The investigation of core-shell nanoparticles has been greatly exciting in biomedical applications, as this remains of prime importance in targeted drug delivery, sensing, etc. In the present work, the polarizability and scattering features of nanoparticles comprised of nano-sized dielectric/metallic core-shell structures were investigated in the fractional dimensional (FD) space, which essentially relates to the confinement of charged particles. For this purpose, three different kinds of metals—namely aluminum, gold and silver—were considered to form the shell, having a common silicon dioxide
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15

Fernandes, Joshua, and Sangmo Kang. "Numerical Study on the Surface Plasmon Resonance Tunability of Spherical and Non-Spherical Core-Shell Dimer Nanostructures." Nanomaterials 11, no. 7 (2021): 1728. http://dx.doi.org/10.3390/nano11071728.

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The near-field enhancement and localized surface plasmon resonance (LSPR) on the core-shell noble metal nanostructure surfaces are widely studied for various biomedical applications. However, the study of the optical properties of new plasmonic non-spherical nanostructures is less explored. This numerical study quantifies the optical properties of spherical and non-spherical (prolate and oblate) dimer nanostructures by introducing finite element modelling in COMSOL Multiphysics. The surface plasmon resonance peaks of gold nanostructures should be understood and controlled for use in biological
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16

Rostamzadehmansoor, S., Mirabdullah Seyed Sadjadi, K. Zare, and Nazanin Farhadyar. "Preparation of Ferromagnetic Manganese Doped Cobalt Ferrite-Silica Core Shell Nanoparticles for Possible Biological Application." Defect and Diffusion Forum 334-335 (February 2013): 19–25. http://dx.doi.org/10.4028/www.scientific.net/ddf.334-335.19.

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Magnetic oxide nanoparticles with proper surface coatings are increasingly being evaluated for clinical applications such as hyperthermia, drug delivery, magnetic resonance imaging, transfection and cell/protein separations. In this work, we investigated synthesis, magnetic properties of silica coated metal ferrite, (CoFe2O4)/SiO2 and manganese doped cobalt ferrite nanoparticles (Mnx-Co1-xFe2O4 with x = 0.02, 0.04 and 0.06)/SiO2 for possible biomedical application. All the ferrites nanoparticles were prepared by co-precipitation method using FeCl3.6H2O, CoCl2.6H2O and MnCl2.2H2O as precursors,
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17

Esquivel, Reynaldo, Iván Canale, Maricela Ramirez, et al. "Poly(N-isopropylacrylamide)-coated gold nanorods mediated by thiolated chitosan layer: thermo-pH responsiveness and optical properties." e-Polymers 18, no. 2 (2018): 163–74. http://dx.doi.org/10.1515/epoly-2017-0135.

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AbstractA core-shell of colloidal metal-responsive polymer provides an innovative model in functional materials. These core-shell nanocomposites offer the possibility to control some properties, such as particle size, surface plasmon resonance and morphology. In this research, we demonstrate the successful synthesis and functionality of gold nanorods (GNR) coated with the polymers chitosan (Ch) and poly(N-isopropylacrylamide) (PNIPAM). The polymer coatings are performed using a two-step method. First, GNR were coated with a thiolated chitosan (GNR-Ch) by replacing hexadecyltrimethylammonium br
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18

Kuznetsov, Vyacheslav A., Petr O. Kushchev, Irina V. Ostankova, et al. "Modern Approaches to the Medical Use of pH- and Temperature-Sensitive Copolymer Hydrogels (Review)." Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 22, no. 4 (2020): 417–29. http://dx.doi.org/10.17308/kcmf.2020.22/3113.

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This article provides the review of the medical use of pH- and temperature-sensitive polymer hydrogels. Such polymers are characterised by their thermal and pH sensitivity in aqueous solutions at the functioning temperature of living organisms and can react to the slightest changes in environmental conditions. Due to these properties, they are called stimuli-sensitive polymers. This response to an external stimulus occurs due to the amphiphilicity (diphilicity) of these (co)polymers. The term hydrogels includes several concepts of macrogels and microgels. Microgels, unlike macrogels, are polym
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19

Paunov, Vesselin N., Paul F. Noble, Olivier J. Cayre, Rossitza G. Alargova, and Orlin D. Velev. "Fabrication of Novel Types of Colloidosome Microcapsules for Drug Delivery Applications." MRS Proceedings 845 (2004). http://dx.doi.org/10.1557/proc-845-aa5.18.

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ABSTRACTNovel colloidosome microcapsules with aqueous gel cores and shells of different polymeric colloid particles have been prepared and characterized. Our preparation technique involves templating water-in-oil emulsions stabilized by either polymeric microrods or polystyrene (PS) latex particles and subsequent gelling of the aqueous phase with a suitable hydrocolloid. The obtained colloidosome microcapsules were transferred in water after dissolving the oil phase in ethanol and multiple centrifugation/washing cycles with ethanol and water. The presence of an aqueous gel core was found to en
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20

"Carbon and Core Shell like Molecular Nanostructures in Cancer diagnosis and Therapy." Advances in Nanoscience and Nanotechnology 2, no. 1 (2018). http://dx.doi.org/10.33140/ann/02/01/00005.

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During the past years, carbon nanotubes (CNTs) have attracted considerable interest since their first discovery. Great progress has been made in the field of nanomaterials given their great potential in biomedical applications. Carbon nanotubes (CNTs), due to their unique physicochemical properties, have become a popular tool in cancer diagnosis and therapy. They are considered one of the most promising nanomaterials with the capability of both detecting the cancerous cells and delivering drugs or small therapeutic molecules to these cells because of the unique structure, extremely high specif
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21

Brar, Basanti, Koushlesh Ranjan, Ankur Palria, et al. "Nanotechnology in Colorectal Cancer for Precision Diagnosis and Therapy." Frontiers in Nanotechnology 3 (September 16, 2021). http://dx.doi.org/10.3389/fnano.2021.699266.

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Colorectal cancer (CRC) is the third most frequently occurring tumor in the human population. CRCs are usually adenocarcinomatous and originate as a polyp on the inner wall of the colon or rectum which may become malignant in the due course of time. Although the therapeutic options of CRC are limited, the early diagnosis of CRC may play an important role in preventive and therapeutic interventions to decrease the mortality rate. The CRC-affected tissues exhibit several molecular markers that may be exploited as the novel strategy to develop newer approaches for the treatment of the disease. Na
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