Academic literature on the topic 'Colorectal tumorigenesis'

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Journal articles on the topic "Colorectal tumorigenesis"

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Abbasi, A. M., I. C. Talbot, A. Forbes, and I. C. Talbot. "Colorectal tumorigenesis." Gut 36, no. 5 (1995): 801. http://dx.doi.org/10.1136/gut.36.5.801-b.

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Shirakami, Yohei, Takayuki Nakanishi, Noritaka Ozawa, et al. "Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats." PLOS ONE 16, no. 5 (2021): e0251942. http://dx.doi.org/10.1371/journal.pone.0251942.

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Prostaglandin E2 receptor EP4 is involved in inflammation and related tumorigenesis in the colorectum. This study aimed to investigate the chemopreventive ability of RQ-15986, a selective EP4 antagonist, in colitis-related colorectal tumorigenesis. Male Kyoto APC delta rats, which have APC mutations, were treated with azoxymethane and dextran sulfate sodium and subsequently administered RQ-15986 for eight weeks. At the end of the experiment, the development of colorectal tumor was significantly inhibited in the RQ-15986-treated group. The cell proliferation of the crypts and tumors in the colo
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Li, Tao, Guoliang Liu, Jiannan Li, et al. "Gastric tumorigenesis after radical resection combined with adjuvant chemotherapy for colorectal cancer: two case reports and a literature review." Journal of International Medical Research 49, no. 4 (2021): 030006052110070. http://dx.doi.org/10.1177/03000605211007050.

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Radical resection with or without adjuvant chemotherapy is a common option for stage II and III colorectal cancer. Few reports exist regarding gastric tumorigenesis, including gastric cancer, gastric intraepithelial neoplasia, and gastric stromal tumor, in patients who received this protocol as the standard treatment for colorectal cancer. We present two cases of gastric tumorigenesis in patients with colorectal cancer following radical resection combined with adjuvant chemotherapy. Both patients underwent gastrectomy and D2 lymphadenectomy for their gastric tumors; neither patient developed r
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Yang, Lin-Sen, Xiao-Jian Zhang, Yin-Yin Xie, Xiao-Jian Sun, Ren Zhao, and Qiu-Hua Huang. "SUMOylated MAFB promotes colorectal cancer tumorigenesis." Oncotarget 7, no. 50 (2016): 83488–501. http://dx.doi.org/10.18632/oncotarget.13129.

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Cho, Dong-Hyung, Yoon Kyung Jo, Seon Ae Roh, et al. "Upregulation of SPRR3 Promotes Colorectal Tumorigenesis." Molecular Medicine 16, no. 7-8 (2010): 271–77. http://dx.doi.org/10.2119/molmed.2009.00187.

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Tanaka, N., N. Matsubara, M. Ikeda, et al. "Molecular colorectal tumorigenesis and gene therapy." Nippon Daicho Komonbyo Gakkai Zasshi 51, no. 9 (1998): 686–686. http://dx.doi.org/10.3862/jcoloproctology.51.686.

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Morin, P. J., B. Vogelstein, and K. W. Kinzler. "Apoptosis and APC in colorectal tumorigenesis." Proceedings of the National Academy of Sciences 93, no. 15 (1996): 7950–54. http://dx.doi.org/10.1073/pnas.93.15.7950.

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Cross, William, Michal Kovac, Ville Mustonen, et al. "The evolutionary landscape of colorectal tumorigenesis." Nature Ecology & Evolution 2, no. 10 (2018): 1661–72. http://dx.doi.org/10.1038/s41559-018-0642-z.

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Fearon, Eric R., and Bert Vogelstein. "A genetic model for colorectal tumorigenesis." Cell 61, no. 5 (1990): 759–67. http://dx.doi.org/10.1016/0092-8674(90)90186-i.

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Wang, W. S., P. M. Chen, and Y. Su. "Colorectal carcinoma: from tumorigenesis to treatment." Cellular and Molecular Life Sciences 63, no. 6 (2006): 663–71. http://dx.doi.org/10.1007/s00018-005-5425-4.

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Dissertations / Theses on the topic "Colorectal tumorigenesis"

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Cripps, Kathryn Jane. "Genetic events in colorectal tumorigenesis." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/27836.

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More is known about the genes involved in colorectal tumorigenesis than for any other human cancer. Mutations have been identified in many genes, including the <I>K-ras</I> oncogene and the <I>APC, MCC, DC</I> and <I>p53</I> tumour suppressor genes. However, whilst much is known about these events there are many questions that remain unanswered. Three specific questions involving <I>p53, MCC</I> and <I>APC</I> were addressed in this thesis. Firstly, it has been previously assumed that point mutation of the <I>p53</I> gene inevitably resulted in a permanently stabilised protein product. To addr
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Kaidi, Abderrahmane. "The role of hypoxia in colorectal tumorigenesis." Thesis, University of Bristol, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439670.

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Moore, Amy Elizabeth. "The role of HGF/Met signalling in colorectal tumorigenesis." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544331.

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Chell, Simon D. "The role of prostaglandin synthesis and signalling in colorectal tumorigenesis." Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413674.

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Jankowski, Janusz Antoni Zygmunt. "Constitutive gene expression during colorectal tumorigenesis : in vivo and in vitro." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321753.

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Morral, Martínez Clara 1989. "The Nucleolus : a connection between cell fate and tumorigenesis in colorectal cancer." Doctoral thesis, Universitat Pompeu Fabra, 2017. http://hdl.handle.net/10803/663807.

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El càncer de colon es caracteritza per presentar una composició cel·lular heterogènia en la qual només un subgrup de cèl·lules retenen la capacitat de contribuir en el manteniment i creixement del tumor. L‘investigació duta a terme en aquesta tesis es focalitza en estudiar aquelles funcions biològiques que estan específicament enriquides en aquesta subpoblació tumoral comparat amb altres cèl·lules cancerígenes que no tenen potencial tumoral. A partir de dades obtingudes en analitzar l’expressió genètica de cèl·lules mare normals i tumorals, hem descobert que l’activitat nucleolar està espe
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Ilantzis, Christian. "Role of human carcinoembryonic antigen (CEA) in colorectal tumorigenesis : a tissue architecture model." Thesis, McGill University, 1998. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35898.

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Human carcinoembryonic antigen (CEA) and the related CEA family member nonspecific cross-reacting antigen (NCA), function in vitro as intercellular adhesion molecules. Changes in the expression pattern of CEA and NCA in a wide variety of cancerous tissues has raised the possibility that they could contribute to neoplastic and malignant transformation by influencing tissue architecture and differentiation. This study revisits the expression pattern of CEA and NCA in colorectal tumorigenesis by emphasizing the accurate quantitation of cell-surface levels in the context of tissue architecture. FA
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Ilantzis, Christian. "Role of human carcinoembryonic antigen (CEA) in colorectal tumorigenesis, a tissue architecture model." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ50189.pdf.

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Kostic, Aleksandar David. "Deep Sequencing and Functional Analyses Identify a Role of Fusobacterium Species in Colorectal Tumorigenesis." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10843.

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The tumor microenvironment is a complex community consisting of neoplastic cells, surrounding stromal cells, a broad array of immune cells, and a microbiota. By sheer numbers, the microbiota has its greatest manifestation in colorectal cancer (CRC) because the colon contains up to 100 trillion bacteria, outnumbering human cells by a factor of 10 and encoding a gene-content that is 100-fold larger than that of the human genome. Indeed, previous studies using germ-free mice in a variety of genetic backgrounds have demonstrated that the microbiota can impact colorectal tumorigenesis. In addition,
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Okuchi, Yoshihisa. "Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis." Kyoto University, 2016. http://hdl.handle.net/2433/217738.

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Book chapters on the topic "Colorectal tumorigenesis"

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Dheer, Rishu, Julie M. Davies, and Maria T. Abreu. "Inflammation and Colorectal Cancer." In Intestinal Tumorigenesis. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19986-3_8.

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Ushio, Kyosuke. "Hereditary Nonpolyposis Colorectal Cancer and Tumorigenesis in the Human Body." In Hereditary Colorectal Cancer. Springer Japan, 1990. http://dx.doi.org/10.1007/978-4-431-68337-7_16.

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Young, Joanne P., and Peter W. Laird. "DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis." In Genetics of Colorectal Cancer. Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-09568-4_4.

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Wang, Weicang, Katherine Z. Sanidad, and Guodong Zhang. "Cytochrome P450 Eicosanoid Signaling Pathway in Colorectal Tumorigenesis." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-21735-8_11.

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Bertagnolli, Monica M. "Cyclooxygenase-2 and Chronic Inflammation: Drivers of Colorectal Tumorigenesis." In Energy Balance and Gastrointestinal Cancer. Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-2367-6_10.

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Perera, Thushanthi, Yumie Takata, and Gerd Bobe. "Grain Legume Consumption Inhibits Colorectal Tumorigenesis: A Meta-Analysis of Human and Animal Studies." In Grain Legumes. InTech, 2016. http://dx.doi.org/10.5772/63099.

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Okayasu, Isao, Tsutomu Yoshida, Tetuo Mikami, et al. "Mucosal Remodeling and Alteration of Stromal Microenvironment in Ulcerative Colitis as Related to Colorectal Tumorigenesis." In Ulcerative Colitis - Epidemiology, Pathogenesis and Complications. InTech, 2011. http://dx.doi.org/10.5772/25362.

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Conference papers on the topic "Colorectal tumorigenesis"

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Leggett, Barbara A. "Abstract IA05: The serrated pathway of colorectal tumorigenesis." In Abstracts: AACR Special Conference: Colorectal Cancer: From Initiation to Outcomes; September 17-20, 2016; Tampa, FL. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.crc16-ia05.

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Sanchez-Martin, Victoria. "G-quadruplexes and DNA damage in colorectal cancer tumorigenesis." In The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response. MDPI, 2021. http://dx.doi.org/10.3390/iecc2021-09198.

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Choi, Yuri, Chae Hwa Kwon, Seon Jin Lee, et al. "Abstract 3566:SLCO4A1-AS1promotes tumorigenesis of colorectal cancer by stabilizingSLCO4A1." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3566.

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Drury, James M., Naser Jafari, B. Mark Evers, and Yekaterina Y. Zaytseva. "Abstract 1443: Overexpression of CD36 promotes tumorigenesis in colorectal cancer." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-1443.

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Choi, Yuri, Chae Hwa Kwon, Seon Jin Lee, et al. "Abstract 3566:SLCO4A1-AS1promotes tumorigenesis of colorectal cancer by stabilizingSLCO4A1." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3566.

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Bian, Benjamin, Sébastien Mongrain, Francois Boudreau, and Nathalie Rivard. "Abstract 1505: The role of cathepsin B in colorectal tumorigenesis." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1505.

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Blanco, Fernando F., Sandhya Sanduja, Lisa Young, and Dan Dixon. "Abstract 1225: Regulation of ARE-mediated mRNA decay during colorectal tumorigenesis." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1225.

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Chien, Chun Wei, Yen-Yu Lai, Bo-Wen Lin, Shao-Chieh Lin, Jenq-Chang Lee, and Shaw-Jenq Tsai. "Abstract 5258: Overexpressed TYRO3 in colorectal cancer regulates tumorigenesis and metastasis." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-5258.

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Shureiqi, Imad, Dongning Chen, R. Sue Day, et al. "Abstract 2897: Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-2897.

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Zuo, Xiangsheng, Rui Tian, Shen Gao, et al. "Abstract 3819: PPAR-delta promotes Wnt/B-catenin-driven colorectal tumorigenesis." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3819.

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