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Journal articles on the topic 'Combined drugs'

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1

Stevens, D. A., B. J. Kullberg, E. Brummer, A. Casadevall, M. G. Netea, and A. M. Sugar. "Combined treatment: antifungal drugs with antibodies, cytokines or drugs." Medical Mycology 38, no. 1 (2000): 305–15. http://dx.doi.org/10.1080/mmy.38.1.305.315.

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Stevens, D. A., B. J. Kullberg, E. Brummer, A. Casadevall, M. G. Netea, and A. M. Sugar. "Combined treatment: antifungal drugs with antibodies, cytokines or drugs." Medical Mycology 38, s1 (2000): 305–15. http://dx.doi.org/10.1080/mmy.38.s1.305.315.

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3

KANIUK, M. I. "COMBINED NANOCHEMOTHERAPY USING DOXORUBICIN AND CURCUMIN AS AN EXAMPLE." Biotechnologia Acta 16, no. 1 (2023): 5–20. http://dx.doi.org/10.15407/biotech16.01.005.

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The aim of the work was to review literature data on combined nanochemotherapy using the example of two drugs ̶doxorubicin and curcumin. Special attention was paid to the use of substances with synergistic properties in one nanoparticle, capable to penetrate into living cell. The method of combined chemotherapy of nanopreparations improves processing efficiency. The technique of using nanocontainers with synergistic drugs in combination with ligands reduces the side effects of chemotherapy drugs. Results. Literature data indicate that the use of nanopreparations contributes the rapid creation
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4

&NA;. "Combined antiparkinsonian drugs increase cardiovascular dysfunction." Inpharma Weekly &NA;, no. 1419 (2004): 19. http://dx.doi.org/10.2165/00128413-200414190-00045.

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&NA;. "Combined antiparkinsonian drugs increase cardiovascular dysfunction." Reactions Weekly &NA;, no. 983 (2004): 5. http://dx.doi.org/10.2165/00128415-200409830-00013.

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6

Ghodse, Hamid. "Combined use of drugs and alcohol." Current Opinion in Psychiatry 7, no. 3 (1994): 249–51. http://dx.doi.org/10.1097/00001504-199405000-00010.

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7

Ghia, Paolo. "Ibrutinib: better combined with other drugs?" Lancet Oncology 15, no. 10 (2014): 1043–44. http://dx.doi.org/10.1016/s1470-2045(14)70388-2.

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8

Shipman, Lydia. "Repurposed drugs combined to amplify autophagy." Nature Reviews Cancer 15, no. 11 (2015): 636–37. http://dx.doi.org/10.1038/nrc4033.

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Merk, Wojciech, and Krzysztof Kucia. "Combined use of ECT and psychotropic drugs." Psychiatria Polska 49, no. 6 (2015): 1241–53. http://dx.doi.org/10.12740/pp/37462.

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10

GS, Lavekar. "Concept of Integrated Drugs Development." Journal of Natural & Ayurvedic Medicine 7, no. 3 (2023): 1–4. http://dx.doi.org/10.23880/jonam-16000413.

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Drugs are an integral part of treatment in health care, it is a belief that the drugs should be free from side effects should be safe and not to create any disease. The chemical or allopathic drugs which are having some side effects may be combined with Ayurveda herbal drugs to pacify their side effects or bring to minimal level. Another aspect is that the Ayurved herbal drugs are slow and weak in action, but quite safe, on other side the allopathic drugs are comparatively fast, bit strong but with some side effects. If these two are combined like an example of anti-diabetic allopathic drug me
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11

Tannock, I. F. "Treatment of cancer with radiation and drugs." Journal of Clinical Oncology 14, no. 12 (1996): 3156–74. http://dx.doi.org/10.1200/jco.1996.14.12.3156.

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PURPOSE To review the current status and future prospects of combined treatment of cancer with radiation and drugs. DESIGN A review of (1) mechanisms whereby combined use of radiation and drugs might lead to improved therapeutic benefit for the treatment of cancer; (2) problems related to the design and analysis of clinical trials that evaluate combined modality treatment; and (3) clinical results of larger randomized trials that have compared combined versus single modality treatment for various types of cancer. RESULTS Improvement in the therapeutic index depends on exploitation of the biolo
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12

Hansson, Lennart. "Combined Action Drugs in the Treatment of Hypertension." Drugs 36, Supplement 6 (1988): 26–30. http://dx.doi.org/10.2165/00003495-198800366-00006.

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13

Rybak, Leonard P. "The combined effects of ototoxic drugs and noise." Journal of the Acoustical Society of America 101, no. 5 (1997): 3100. http://dx.doi.org/10.1121/1.418899.

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14

Radics, J. "Combined application of psychotropic drugs in schizoaffective disorder." European Psychiatry 23 (April 2008): S138—S139. http://dx.doi.org/10.1016/j.eurpsy.2008.01.864.

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15

Costa, Sonya, Marisa Machado, Cláudia Cavadas, and Maria do Céu Sousa. "Antileishmanial activity of antiretroviral drugs combined with miltefosine." Parasitology Research 115, no. 10 (2016): 3881–87. http://dx.doi.org/10.1007/s00436-016-5153-8.

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16

Blank, Mikhail, and Olga Blank. "SYNCHRONOUS COMBINED THERAPY IN ONCOLOGY." Problems in oncology 64, no. 4 (2018): 490–92. http://dx.doi.org/10.37469/0507-3758-2018-64-4-490-492.

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There are presented the main principles and possibilities of simultaneous chemoradiotherapy, including intra-tumoral administration of antitumor drugs in combination with irradiation of primary bone tumors with soft tissue components, metastatic damage of bones, soft tissue tumors as well as superficial tumors and metastases. On the example of 23 patients the high efficiency of synchronous combined therapy is showed. The possibility of using low total doses of ionizing radiation in order to significantly increase the local cytotoxicity of antitumor drugs directly in the tumor focus is substant
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17

Sandro, Pinheiro da Costa, Julien Salvarani Borges Pedro, Silva Quintão Laís, et al. "PHARMACOLOGICAL ASPECTS IN THE COMBINATION OF ANTIDEPRESSANTS FOR THE TREATMENT OF OBESITY: AN INTEGRATED REVIEW." RevistaFT 27, no. 123 (2023): 20. https://doi.org/10.5281/zenodo.8083720.

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Currently, the search for rapid weight loss has provided elaborations of different masterful formulations with various associated substances, among which antidepressants stand out. Recent years have seen the approval of a number of new anti-obesity drugs. Most of these influence hypothalamic appetite pathways via dopaminergic and serotonergic signaling. Combination therapies, allowing lower doses to minimize potential off-target effects. In this sense, it is understood that the use of antidepressants in slimming formulations is effective in reducing the symptoms of bulimia and treating the ass
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18

Wang, Jie, Xiaochen Yang, Bo Feng, et al. "Is Yangxue Qingnao Granule Combined with Antihypertensive Drugs, a New Integrative Medicine Therapy, More Effective Than Antihypertensive Therapy Alone in Treating Essential Hypertension?" Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/540613.

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Background. Yangxue Qingnao granule (YQG) combined with antihypertensive drugs, a new integrative medicine therapy, has been widely used for essential hypertension (EH) in China. This study aims to assess the current clinical evidence of YQG combined with antihypertensive drugs for EH.Methods. Randomized controlled trials(RCTs) published between 1996 and 2012 on YQG combined with antihypertensive drugs versus antihypertensive drugs in treating EH were retrieved from six major electronic databases, including The Cochrane Library, PubMed, Chinese National Knowledge Infrastructure, Chinese Scient
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19

Behei, Nataliia S., and Oksana V. Tryhubchak. "Marketing research of combined drugs for treatment of cardiovascular diseases." Česká a slovenská farmacie 71, no. 5 (2022): 79–94. http://dx.doi.org/10.5817/csf2023-2-79.

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The work is devoted to the results of complex marketing research of all combined cardiovascular drugs. The market of combined drugs from group C according to the ATC classification in 41 countries of the world during 2019–2022 was analyzed. Segment markets of the 27 European Union countries, Albania, Belarus, Bosnia and Hercegovina, Canada, Colоmbia, Great Britain, India, Moldova, Norway, Russian Federation, Switzerland, and Ukraine, were studied. The pharmaceutical market of Australia and the United States were also studied. The structure of this group of drugs was characterized, and the most
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20

Gigolyan, M. O., and M. I. Cheryomkin. "THE MORPHOLOGY OF SOME ORGANS IN CASE OF COMBINED INTOXICATION OF ALCOHOL AND DRUGS." Amur Medical Journal, no. 15-16 (2016): 46–47. http://dx.doi.org/10.22448/amj.2016.15-16.46-47.

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21

Tikhomirov, A. L., T. A. Yudina, and D. I. Burchakov. "Combined oral contraceptives in improving quality of young women’s lives." Medical alphabet 1, no. 1 (2019): 15–18. http://dx.doi.org/10.33667/2078-5631-2019-1-1(376)-15-18.

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Compliance with the use of combined hormonal contraceptive drugs containing drospirenone is presented. The use of such drugs enhances the use of hormonal contraception. The distinctive features of the drugs are considered: reliable contraception, reduced severity of side effects, additional positive preventive and curative effects.
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22

Okovityi, Sergey V., Karina L. Raikhelson, and Veronika A. Prikhodko. "Combined hepatoprotective pharmacotherapy for liver disease." Experimental and Clinical Gastroenterology, no. 7 (October 7, 2022): 5–20. http://dx.doi.org/10.31146/1682-8658-ecg-203-7-5-20.

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Fixed-dose drug products as well as non-fixed hepatoprotective drug combinations are commonly used in modern clinical practice. Combined and concurrent drug use makes it possible to augment the pharmacological effects of individual agents, or extend the range of their potential indications. The drugs most commonly considered for combination therapy include essential phospholipids, glycyrrhizinic acid, ursodeoxycholic acid, silibinin, and S-adenosylmethionine. This paper discusses the rationale for combined use of liver-targeting drugs from a pathogenetic viewpoint, and provides a review of the
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23

Sampson, Michael. "Antiarrhythmic drugs. Part 3: rate-control drugs." British Journal of Cardiac Nursing 14, no. 11 (2019): 1–11. http://dx.doi.org/10.12968/bjca.2019.0079.

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Rate-control drugs are used to reduce the ventricular rate during atrial arrhythmias and are widely used in both primary and secondary care. In this final instalment of a three-part article series, we evaluate three commonly used rate-control agents: bisoprolol, diltiazem, and digoxin. Of these, bisoprolol has the widest range of indications as it is also used in the prevention of ventricular arrhythmias. It has the best safety profile of the three drugs owing to its combined renal and hepatic excretion. Diltiazem and digoxin have a narrower range of use and carry a greater risk of toxicity as
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24

Grishsin, О. V. "SAFETY OF THE COMBINED EMERGENCY ANTIHYPERTENSIVE THERAPY." EMERGENCY MEDICAL CARE 22, no. 1 (2021): 32–39. http://dx.doi.org/10.24884/2072-6716-2021-22-1-32-39.

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In 91 patients with increased blood pressure, the efficacy and safety of three combinations of antihypertensive drugs was clarified. It was proved that the use of hourly monitoring of changes in blood pressure immediately after the provision of emergency therapy with the help of sublingual use of combinations of antihypertensive drugs allows for objective control of the time of onset and duration of the preservation of the therapeutic effect and to assess the likelihood and severity of repeated increase and excessive decrease in blood pressure. It has been shown that combinations of antihypert
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25

Zhang, Bowen. "Analysis of gastric cancer medication by exploring fluorouracil drugs." Theoretical and Natural Science 58, no. 1 (2024): 28–34. http://dx.doi.org/10.54254/2753-8818/58/20241325.

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Abstract. Gastric cancer (GC), as one of the most important types of cancer with a very high incidence rate in China, is in urgent need of treatment. China has made certain progress, such as the widespread use of fluorouracil and other drugs in the treatment of gastric cancer, as well as the use of various treatment methods such as surgery and chemotherapy. This article aims to explore the efficacy of fluorouracil drugs in the treatment of gastric cancer and their combined application with other drugs. By analyzing the correlation between peripheral blood platelet levels and the efficacy of ox
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26

Palmeira-de-Oliveira, Ana, Ana Rita Ramos, Carlos Gaspar, Rita Palmeira-de-Oliveira, Paula Gouveia, and José Martinez-de-Oliveira. "In VitroAnti-CandidaActivity of Lidocaine and Nitroglycerin: Alone and Combined." Infectious Diseases in Obstetrics and Gynecology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/727248.

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The aim of this work was to study the anti-Candidaactivity of lidocaine and nitroglycerin alone and in combination. TenCandidastrains were included, corresponding to 1 collection type strain (ATCC 10231) and 9 clinical isolates: 4C. albicans, 2C. glabrata, 1C. tropicalis, 1C. krusei, and 1C. parapsilosis. The CLSI reference M27-A3 micromethod was used to determine the anti-Candidaactivity of the drugs alone; minimal inhibitory and lethal concentrations were determined. The classic checkboard technique was used to determine the activity of combined drugs. Lidocaine fungicidal effect was dosedep
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27

Ibragimova, Muazam, and Zohida Shamshiyeva. "INTOXICATION PSYCHOSES CAUSED BY COMBINED DRUG USE." MODERN SCIENCE AND RESEARCH 3, no. 3 (2024): 11–24. https://doi.org/10.5281/zenodo.10734306.

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<em>In recent years, there has been a trend in all developed countries of the world for the rapid spread of the combined consumption of psychoactive substances, the market of which is increasingly expanding due to the emergence of new synthetic drugs and drugs. Cases of the appearance of intoxicating psychoses as a result of the combined use of psychoactive substances of various pharmacological groups have become significantly more frequent, they are practically not found in the mono-consumption of classical opioids, and rarely occur with an overdose of natural cannabinoids. </em>
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Abd-Alkareem, Haider Fathi, Ahmed Haider Jaber, Ali Qasim Ibrahim, and Murtadha Abdulhamid Fanok. "Lipid lessening drugs overview." GSC Biological and Pharmaceutical Sciences 10, no. 1 (2020): 090–95. https://doi.org/10.5281/zenodo.4280966.

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Lipid lessening drugs are groups of drugs used to treat the conditions or diseases that associated with elevated blood levels of lipids (cholesterol, triglyceride) and low-density lipoprotein (LDL). These conditions known as dyslipidemias, which is hypercholesterolemia, hypertriglyceridemia, or combined hyperlipidemia. Many studies found that dyslipidemias inclined and increase the risk of other diseases such as atherosclerosis, diabetes mellitus, and coronary arteries disease.
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29

Limanova, O. A., L. E. Fedotova, and O. A. Gromova. "Combined oral contraceptives and treatment of new coronavirus infection (COVID-19): aspects of drug interactions." Infekcionnye bolezni 19, no. 1 (2021): 149–58. http://dx.doi.org/10.20953/1729-9225-2021-1-149-158.

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This article discusses the problem of drug interactions between combined oral contraceptives on the example of Belara® (30 μg of ethinyl estradiol + 2 mg of chlormadinone acetate; Gedeon Richter, Hungary) and medications recommended for the treatment of new coronavirus infection (COVID-19) and concomitant disorders at the pharmacodynamic and pharmacokinetic levels with an assessment of the efficacy and safety of therapy for females. We described safe, potentially dangerous, and dangerous combinations of these drugs. Key words: new coronavirus infection (CAVID-19), combined oral contraceptives,
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Eshonkhuzhaev, О. О. "Pharmacoepidemiological analysis of combined antibacterial therapy in young children with bronchopulmonary pathology." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 3 (June 10, 2025): 75–76. https://doi.org/10.33920/med-13-2503-16.

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The peculiarities of using antibacterial drugs in pediatrics are determined by the anatomical and physiological characteristics of a growing organism and the more frequent use of antibiotics in children thanaa in adults. These same physiological characteristics of the child's body, leading to changes in the pharmacokinetics of drugs, can have a significant impact on the choice and dosage of anti-infective chemotherapy drugs. This becomes especially relevant in the case of a combination form of treatment with antibacterial drugs. One of the difficult tasks that a pediatrician faces when using a
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31

Usov, Konstantin. "ABOUT THE DISADVANTAGES OF MODERN COMBINED ANTI-TUBERCULOSIS DRUGS." Modern Technologies and Scientific and Technological Progress 2022, no. 1 (2022): 281–82. http://dx.doi.org/10.36629/2686-9896-2022-1-281-282.

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32

Yarovoy, S. K. "Herbal drugs in combined therapy and metaphylaxis of nephrolithiatis." Pacific Medical Journal 63, no. 1 (2016): 19–23. http://dx.doi.org/10.17238/pmj1609-1175.2016.1.19-23.

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33

NAKAMURA, CHIZUKO. "Effect of combined drugs on pharmacokinetics of Cefteram pivoxil." Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 20, no. 1 (1989): 253–54. http://dx.doi.org/10.3999/jscpt.20.253.

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34

Fedotova, Arina, and Alena Sheverduk. "COMBINED USE OF DRUGS TO IMMOBILIZE EGYPTIAN FLYING DOGS." Bulletin of KSAU, no. 6 (January 22, 2025): 145–50. https://doi.org/10.36718/1819-4036-2023-6-145-150.

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The purpose of research is to evaluate the effectiveness of the combination of Zoletil 50 and Medetomidine for the immobilization of Egyptian flying dogs. A literature review on the anesthesia of Egyptian flying dogs and the results of our own research using the Zoletil 50 + Medetomidine anesthesia regimen are given. The effectiveness of the use of the combination of preparations Zoletil 50 + Medetomidine and their effect on the anesthesia process and the organism of animals was evaluated in comparison with the results of various protocols used for fruit bats. The work was carried out on clini
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35

van Gijn, J., and A. Algra. "Secondary Stroke Prevention with Drugs: Single or Combined Therapy?" Cerebrovascular Diseases 9, no. 3 (1999): 24–28. http://dx.doi.org/10.1159/000047551.

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36

Cerrone, Maddalena, Margherita Bracchi, Sean Wasserman, et al. "Safety implications of combined antiretroviral and anti-tuberculosis drugs." Expert Opinion on Drug Safety 19, no. 1 (2019): 23–41. http://dx.doi.org/10.1080/14740338.2020.1694901.

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37

Silva, Tedesco H., T. V. S. Freitas, C. R. Felipe, et al. "ADVANTAGES OF BASILIXIMAB INDUCTION COMBINED WITH MODERN IMMUNOSUPPRESSIVE DRUGS." Transplantation Journal 90 (July 2010): 620. http://dx.doi.org/10.1097/00007890-201007272-01181.

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38

Roig, Teresa, and Jordi Bermúdez. "Microcalorimetric evaluation of the effect of combined chemotherapeutic drugs." Biochimica et Biophysica Acta (BBA) - General Subjects 1244, no. 2-3 (1995): 283–90. http://dx.doi.org/10.1016/0304-4165(95)00026-8.

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39

Fan, Wenqing. "Combined nanotechnology with monoclonal antibody drugs for cancer immunotherapy." Highlights in Science, Engineering and Technology 102 (July 11, 2024): 461–66. https://doi.org/10.54097/k0dm7x19.

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Cancer, a genetic disease characterized by uncontrolled cell growth and spread, remains a major global health challenge, with its complexity lying in the myriad ways it can manifest and resist treatment. It is marked by the accumulation of mutations that lead to genomic instability, contributing to its lethality and the difficulty in treatment. Epidemiologically, cancer constitutes a significant burden worldwide, being a leading cause of death. The International Agency for Research on Cancer projects a relentless increase in cancer incidence and mortality, underscoring the urgent need for more
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40

Vailenko, D. S., T. P. Tananakina, Yu G. Pustovoy, V. V. Baranova, V. I. Shmatkov, and A. R. Zanin. "Combined Use of Broad-Spectrum Antibiotics in Phthisiology." Fundamental and Clinical Medicine 9, no. 1 (2024): 8–16. http://dx.doi.org/10.23946/2500-0764-2024-9-1-8-16.

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Aim. To investigate pharmacokinetic and pharmacodynamic interactions of levofloxacin, kanamycin and linezolid in combined chemotherapy of multidrug-resistant tuberculosis.Materials and Methods. We investigated pharmacological interactions between levofloxacin, kanamycin and linezolid using GalaxyWEB GalaxySagittarius – AlphaFold software.Results. We found that levofloxacin can interact through the carboxyl group (–COOH) with compounds containing an amino group, in particular with linezolid and kanamycin, in order to form a carbamide bond -CO-NH-. Levofloxacin is also able to form an azomethine
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Trovò, Mauro G., Marco Gigante, Emilio Minatel, Carlo Gobitti, and Giovanni Franchin. "Combined Modality Treatment of Locally Advanced Lung Cancer." Tumori Journal 84, no. 2 (1998): 259–69. http://dx.doi.org/10.1177/030089169808400227.

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This paper describes the mechanisms of action of ionizing radiations combined with antineoplastic drugs. Some relevant drugs for the combined modality treatments of locally advanced lung cancer are reported. The meta-analyses including randomized trials comparing single agent (radiotherapy or chemotherapy) versus combined chemoterapy and radiotherapy in patients with unresectable non small cell lung cancer and limited small cell lung cancer are then reviewed. The clinical outcome in relation to different schedules of chemoradiotherapy (sequential, alternating and concurrent) is also focussed.
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42

Abritsova, M. V., and N. R. Torchua. "Combined drug therapy of hemorrhoidal bleeding." Ambulatornaya khirurgiya = Ambulatory Surgery (Russia) 22, no. 1 (2025): 153–59. https://doi.org/10.21518/akh2025-017.

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Hemorrhoidal disease is one of the most common proctological pathologies. The main risk factors are physical inactivity, obesity, pregnancy, and chronic constipation, including dysynergic bowel movements. Systemic bioflavonoids (diosmin and hesperidin) demonstrate high efficacy, especially in the early stages of the disease. These substances strengthen blood vessels, reduce inflammation and improve microcirculation. Studies confirm that the combination of systemic flavonoids with topical agents such as sodium alginate accelerates the regression of symptoms. Sodium alginate in the form of candl
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43

Wang, Jie, Kuiwu Yao, Xiaochen Yang, et al. "Chinese Patent Medicine Liu Wei Di Huang Wan Combined with Antihypertensive Drugs, a New Integrative Medicine Therapy, for the Treatment of Essential Hypertension: A Systematic Review of Randomized Controlled Trials." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/714805.

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Objectives. To assess the beneficial and adverse effects of Liu Wei Di Huang Wan (LWDHW), combined with antihypertensive drugs, for essential hypertension.Methods. Five major electronic databases were searched up to August 2012 to retrieve any potential randomized controlled trials designed to evaluate the clinical effectiveness of LWDHW combined with antihypertensive drugs for essential hypertension reported in any language, with main outcome measures as blood pressure. The quality of the included studies was assessed with the Jadad scale and a customized standard quality assessment scale.Res
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44

Tsantili-Kakoulidou, Anna, and Vassilis Demopoulos. "Drug-like Properties and Fraction Lipophilicity Index as a combined metric." ADMET and DMPK 9, no. 3 (2021): 177–90. http://dx.doi.org/10.5599/admet.1022.

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Fraction Lipophicity Index (FLI) has been developed as a composite drug-like metric combining logP and logD in a weighted manner. In the present study an extended data set confirmed the previously established drug-like FLI range 0-8 using two calculation systems for logP /logD assessment, the freeware MedChem Designer and ClogP. The dataset was split into two classes according to percentage of fraction absorbed (%FA) - class 1 including drugs with high to medium absorption levels and class 2 including poorly absorbed drugs. The FLI and FLI© (ClogP based FLI) drug-like range covers 93% and 90 %
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45

Gopal, Garg, Saraf Shailendra, and Saraf Swarnlata. "Simultaneous estimation of ramipril and metoprolol tartrate in combined dosage forms." Journal of Indian Chemical Society Vol. 84, Jun 2007 (2007): 609–11. https://doi.org/10.5281/zenodo.5820884.

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Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur-492 010, Chhattisgarh, India <em>E-mail </em>: swarnlata_ saraf@rediffmail.com <em>Fax</em> : 91-0771-2263773 <em>Manuscript received 12 October 2006, accepted 3 April 2007</em> Four new analytical methods were developed based on the simultaneous estimation of drugs in a binary mixture without prior separation. In Simultaneous equation method, the drugs were determined by using the absorbance values of ramipril and metoprolol at selected wavelengths, viz. 205 nm and 222.5 nm respectively. The second method depends on the applicat
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Vucelic, D., P. Pesko, D. Stojakov, et al. "Systemic hemostatic drugs." Acta chirurgica Iugoslavica 54, no. 1 (2007): 177–95. http://dx.doi.org/10.2298/aci0701177v.

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Understanding the haemostatic changes is crucial in developing strategies for the management of haemorrhage syndroma. In recent years, the revised model of coagulation ("cell based" model) provided a much more authentic description of the coagulation process. Pharmacological intervention, especially desmopresin, antifibrinolytics (synthetics and nature) and increasingly recombinant activated factor VII are being used in prevention and therapeutically to control bleeding of variety etiologies. Skilful surgery combined with blood saving methods and careful management of blood coagulation will al
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Гончар, А. О., Н. В. Шолойко, and О. О. Комаріда. "Reimbursement of combined antihypertensive medicenes in Ukraine: aspects of inclusion and external reference pricing." Farmatsevtychnyi zhurnal, no. 6 (December 29, 2022): 53–59. http://dx.doi.org/10.32352/0367-3057.6.22.06.

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Cardiovascular diseases (CVD), in particular arterial hypertension (AH), are the main causes of morbidity and mortality, Ukraine is on the 1st place in Europe for mortality from these diseases. Modern clinical guidelines emphasize the use of combined antihypertensive drugs, and improving the accessibility of these medicines for Ukrainian patients with hypertension is relevant. In Ukraine, at the end of 2022, there were no combined antihypertensive drugs in the List of reimbursed drugs. Therefore, there is a need to develop scientific and practical approaches to improve the «Affordable Medicine
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48

Kovaleva, Yu S., and O. A. Kokina. "Polycomponent drugs in the treatment of intertriginous dermatosis." Meditsinskiy sovet = Medical Council, no. 13 (August 9, 2022): 60–65. http://dx.doi.org/10.21518/2079-701x-2022-16-13-60-65.

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The most common localization of dermatoses of combined etiology are intertriginous areas. In recent years, an increase in the number of patients suffering from dermatoses of combined etiology has been recorded. The reasons for this situation can be both irrational therapy and background comorbidities in the patient, as well as a number of anatomical and physiological prerequisites for the formation and maintenance of an inflammatory infectious process with localization, namely in the area of skin folds. The article describes in detail the anatomical and physiological features of these areas, t
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49

Sebaiy, Mahmoud. "Analytical Methods for Determination of Salbutamol, Ambroxol and Fexofenadine." Biotechnology and Bioprocessing 1, no. 1 (2020): 01–11. http://dx.doi.org/10.31579/2766-2314/004.

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In this review article, we will introduce all reported methods that have been developed for determination of certain anti-tussive and anti-histaminic drugs such as salbutamol, ambroxol and fexofenadine in their pure form, combined form with other drugs, combined form with degradation products, and in biological samples. We also will shed the light on the most important combination of drugs that are used for treatment of asthma and related diseases.
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50

Pattan, S. R., A. O. Zanwar, N. B. Wabale, and U. B. Shetkar. "SCOPE AND NEED OF COMBINATION OF ANTIHYPERTENSIVE DRUGS." INDIAN DRUGS 49, no. 05 (2012): 5–19. http://dx.doi.org/10.53879/id.49.05.p0005.

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The recommendation for first-line therapy for hypertension remains a beta blocker or diuretic given in a low dosage. A target blood pressure of less than 140/90 mm Hg is achieved in about 50 percent of patients treated with monotherapy; two or more agents from different pharmacological classes are often needed to achieve adequate blood pressure control. Single-dose combination antihypertension therapyis an important option that combines efficacy of blood pressure reduction and a low side effect profilewith convenient once-daily dosing to enhance compliance. Combination antihypertensives includ
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