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Journal articles on the topic 'Combined TOF and Palate Repair'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

International, Journal of Medical Science and Innovative Research (IJMSIR). "Perioperative Anaesthetic Management for an Isolated or Combined Tetralogy of Fallot (TOF) and Cleft Palate/Lip Repairs - A Systematic Review and Meta-Analysis." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 4 (2024): 59–79. https://doi.org/10.5281/zenodo.15422691.

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<strong>Abstract</strong> The prevalence of cleft lip is 0.3 in every 1000 live births and the combination of cleft lip (CL) and palate(P) in every 1000 live births is 0.45.[1] The CL/P  is commonly associated with various cyanotic and noncyanotic cardiac anomalies including Tetralogy of  Fallot’s (TOF).[2,3] Severe congenital heart disease (CHD) forms are diagnosed and treated before cleft care.[4] Most of the patients with CL/P can be operated on at a median age of 11 months without any serious complications, and intensive care unit admission or mortality.[2] Nowadays, most o

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Kantar, Rami S., William J. Rifkin, Michael J. Cammarata, et al. "Combined Primary Cleft Lip and Palate Repair." Journal of Craniofacial Surgery 30, no. 2 (2019): 384–89. http://dx.doi.org/10.1097/scs.0000000000005039.

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Schulte, Linda J., Paighton C. Miller, Jacob R. Miller, Dilip Nath, and Pirooz Eghtesady. "Technique for Neo-Pulmonary Valve Creation With Living Tissue for Repair of Atrioventricular Septal Defect and Tetralogy of Fallot." World Journal for Pediatric and Congenital Heart Surgery 13, no. 4 (2022): 499–502. http://dx.doi.org/10.1177/21501351221096048.

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Long-standing effects of pulmonary regurgitation after transannular patch repair in Tetralogy of Fallot (ToF) can be especially deleterious in the setting of combined ToF and complete atrioventricular septal defect (CAVSD). We present a technique for a complete repair of combined ToF/CAVSD using right atrial appendage tissue to create a competent neo-pulmonary valve. This technique provides advantages of right heart protection via pulmonary valve competence and the use of living tissue capable of growth with the patient, potentially obviating the need for repeat interventions.

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Wang, Xu. "Combined Repair Surgery for Cleft Lip and Cleft Palate: A 4-Year Clinical Experience." Science Insights 4, no. 2 (2013): 79–80. http://dx.doi.org/10.15354/si.13.rp015.

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Surgical repair is the only method of treatment for patients with cleft lip or/and palate. The cleft lip surgery is usually done when the child is 3 to 6 months old, while cleft palate repair is done between 2 and 3 years old in order to allow the palate to change as the child grows. Here we reported our experience of simultaneous surgeries for both cleft lip and cleft palate with satisfactory results in 48 patients who have not done cleft lip repair at early age. It reduced the treatment time, the patients’ pain, as well as the financial burden of the patients’ family by one operation.

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Dr, Talib Mustafa Jawad, Ali Haroon Dhumad Lami Dr, and Amir Abdul-Adhim Albakaa Dr. "Buccal Mucosa Graft for Cleft Palate Surgery." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 05, no. 01 (2025): 81–90. https://doi.org/10.5281/zenodo.14760205.

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<strong>Background</strong>: Cleft palate repair aims at producing closure of the cleft with reasonable lengthy palate in order to have competent velopharyngeal closure. There are various procedures concentrate on the lengthening of the palate like: Veu Wardill and Kilner, Furlow double opposing Z-plasty, Mukherji bilateral mucosal cheek flap, and Kaplan unilateral mucosal cheek flap etc.   Buccal mucosal flap for nasal layer combined with Z-Plasty in the oral layer of the soft palate is one of these procedure provide reasonable length for cleft palate repair.   <strong>Objective</st

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Smith, D., S. E. F. H. J. Abdullah, A. Moores, and D. M. Wynne. "Post-operative respiratory distress following primary cleft palate repair." Journal of Laryngology & Otology 127, no. 1 (2012): 65–66. http://dx.doi.org/10.1017/s0022215112002563.

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AbstractIntroduction:Infants are obligate nasal breathers. Cleft palate closure may result in upper airway compromise. We describe children undergoing corrective palatal surgery who required unplanned airway support.Setting:Tertiary referral unit.Method:Retrospective study (2007–2009) of 157 cleft palate procedures (70 primary procedures) in 43 patients. Exclusion criteria comprised combined cleft lip and palate, secondary palate procedure, and pre-existing airway support.Results:The children's mean age was 7.5 months and their mean weight 7.72 kg. Eight children were syndromic, and eight unde

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Kaye, Alison, Columbine Che, William L. Chew, Elizabeth A. Stueve, and Shao Jiang. "Cleft Care of Internationally Adopted Children From China." Cleft Palate-Craniofacial Journal 56, no. 1 (2018): 46–55. http://dx.doi.org/10.1177/1055665618771423.

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Objective: To quantify a population of international adoptees from China with cleft lip and/or palate to assess presentations and team management practices. Design: Single institution retrospective. Patients: One hundred one patients with cleft lip and/or palate and history of international adoption from China. Results: Forty-nine males and 52 females were adopted from 2001 to 2014. Median age at arrival was 26 months. A total of 88.1% had a combined cleft lip and palate: 59 unilateral, 30 bilateral. Only 4 patients had isolated cleft palate. A total of 85.6% had cleft lip repair before adopti

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Murthy, Jyotsna. "Descriptive study of management of palatal fistula in one hundred and ninety-four cleft individuals." Indian Journal of Plastic Surgery 44, no. 01 (2011): 041–46. http://dx.doi.org/10.1055/s-0039-1699477.

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ABSTRACT Objective: Palatal fistula is a significant complication following cleft palate repair. The guidelines of management of the palatal fistula is dependent on the type of cleft, site of fistula, condition of surrounding tissue and associated problem. We studied the management and outcome of 194 cleft palate fistula in our institute. Design: We present the descriptive hospital-based study of management of palatal fistula in 194 cleft patients. We have excluded all the syndromic children and children whose anterior palate was not operated as per protocol. Settings: Of 194 cleft palate fist

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Goh, Benjamin K. L., and Hui-Ling Chia. "The Use of Acellular Dermal Matrix in Combination With Pedicled Buccal Fat Pad in Wide Cleft Palate Repair: A Case Report and Literature Review." Cleft Palate-Craniofacial Journal 56, no. 10 (2019): 1381–85. http://dx.doi.org/10.1177/1055665619851915.

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We describe a case of the combined use of acellular dermal matrix and pedicled buccal fat pad (BFP) in a wide U-shaped cleft palate repair. Acellular dermal matrix was used as a “patch” repair for the nasal mucosa defect as opposed to the conventional inlay graft. The advantages include reduced cost and a smaller avascular graft load. Lateral relaxing incisions were made to ensure tension-free closure of oromucosa at midline. Lateral oromucosa defect closure with well-vascularized pedicled BFP ensures enhanced healing, less palatal contracture and shortening, and reduced infection. The palate

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Usama, Ahmed Rana. "Experience of Primary Cleft Lip And Palate At A Tertiary Care Hospital in Pakistan: A 4 Year Retrospective Review." Pakistan Journal of Plastic Surgery 8, no. 2 (2020): 43–46. https://doi.org/10.5281/zenodo.4641671.

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Abstract Objectives: To retrospectively review our experience of primary cleft lip and palate surgery at a tertiary care hospital Methods: This was a retrospective study, reviewing the records of all patients with cleft lip and palate operated in, from September 2012 to October 2016.Data analysis was done using SPSS (16.0). Results: During this period, a total of 316 patients were seen (149 males and 167 females). 60 had isolated cleft palate, 83 had isolated cleft lip and 173 had combined cleft lip and palate. Patient age was meansd(15 days-33 years). A total of 349 procedures were performed

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Schwarz, Richard J. "Combined repair of lip and palate with pharyngoplasty for late presenting clefts." Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 40, no. 4 (2006): 210–13. http://dx.doi.org/10.1080/02844310600723083.

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12

Emmanuel, JK Adu. "Management of Cleft Lip and Palate: A Five Year Review." Archives of Otolaryngology and Rhinology 3, no. 1 (2017): 023–26. https://doi.org/10.17352/2455-1759.000038.

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<strong>Introduction:</strong> Clefts of the lip may cause cosmetic and social problems. Clefts of the palate may affect feeding, speech and hearing.  <strong>Objective:</strong> To document the clinical and epidemiological features, surgical techniques (Millard’s repair for cleft lip, and the Oxford palatoplasty for cleft palate) and the outcome of treatment of patients with cleft lip and palate at Komfo Anokye Teaching Hospital (KATH), Kumasi, between January 2010 and December 2014. <strong>Patients and Methods:</strong> Data on cleft patients were retrieved from the records of th

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von Ungern-Sternberg, Britta S., Ferenc Petak, Zoltan Hantos, and Walid Habre. "Changes in Functional Residual Capacity and Lung Mechanics during Surgical Repair of Congenital Heart Diseases." Anesthesiology 110, no. 6 (2009): 1348–55. http://dx.doi.org/10.1097/aln.0b013e3181a32887.

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Background To characterize the impact of lung volume changes in the lung function impairment after the surgical repair of congenital heart diseases, combined measurements of functional residual capacity, lung clearance index, and respiratory mechanics were performed in children with hypoperfused lungs (tetralogy of Fallot [TOF]) or with pulmonary hyperperfusion (ventricular septal defect [VSD]). Methods Lung volume and clearance were assessed by using a sulfur hexafluoride washout technique, and the mechanical properties of the respiratory system were assessed using a low-frequency oscillation

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Mardiyantoro, Fredy, Diwya Nugrahini Hapsari, and Lalita El Milla. "MODIFIED FEEDING BOTTLE FOR INFANT WITH CLEFT LIP AND PALATE AT THE PERIPHERAL AREA: A CASE REPORT." Jurnal Ilmiah dan Teknologi Kedokteran Gigi 15, no. 1 (2019): 29. http://dx.doi.org/10.32509/jitekgi.v15i1.695.

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Introduction:A newborn can suck at breast and latch well to get breast milk, but infants born with cleft lip and palate have difficulties to press the nipple by their tongues towards palatal direction. Case:A 10-day-old female infant came with complaint of not being able to breastfeed from a normal bottle and accordingly need to use spoon for milk feeding. She was planned to perform first step operation at 3 months with minimum 10 pounds of body weight. For nutrient intake, nasogastric tube had been placed on the patient. Case management :At the first visit, impression procedure was performed

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Liu, Xiyang, and Zhenqi Chen. "Effects of Palate Repair on Cranial Base and Maxillary Morphology in Patients With Unilateral Complete Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 55, no. 10 (2018): 1367–74. http://dx.doi.org/10.1177/1055665618768544.

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Objective: To identify the effects of palate repair on cranial base and maxillary morphology in patients with unilateral cleft lip and palate (UCLP) and to discover the relevance between cranial base and maxilla through cephalometric analysis. Design: Retrospective. Patients: Thirty-seven UCLP patients with operated lip (OL) and unoperated palate constituted OL group and were classified into 5 cervical vertebral maturation (CVM) stages. Thirty-seven UCLP patients with operated lip and palate (OLP) and 37 noncleft people with skeletal class I malocclusion were CVM- and sex-matched with the OL g

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Kochar, Lalit, Deepak V. Chauhan, S. P. Bajaj, and Akash Juneja. "Evaluation of Eustachian tube function in patients of cleft palate and effects of palatoplasty on these findings." International Journal of Otorhinolaryngology and Head and Neck Surgery 7, no. 9 (2021): 1473. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20213282.

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<p class="abstract"><strong>Background:</strong> Isolated cleft palate and cleft palate and cleft lip patients have poor Eustachian tube function which results in hearing impairment that too in the speech formative years. Aim of study was to evaluate tympanometric findings in patient of cleft palate and effect of palatoplasty on both short term and long term postoperatively.</p><p class="abstract"><strong>Methods:</strong> The subjects consisted of patients attending the cleft lip and palate clinic. This was a combined clinic consisting of department o

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Salloum, Mariah L., Kyle R. Eberlin, Navil Sethna, and Usama S. Hamdan. "Combined Use of Infraorbital and External Nasal Nerve Blocks for Effective Perioperative Pain Control during and after Cleft Lip Repair." Cleft Palate-Craniofacial Journal 46, no. 6 (2009): 629–35. http://dx.doi.org/10.1597/08-142.1.

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Perioperative analgesia in patients undergoing cleft lip and palate repair is complicated by the risk of postoperative airway obstruction. We describe a technique of combined infraorbital and external nasal nerve blocks to reduce the need for opioid analgesia. Using this technique, we have successfully performed cleft lip repair under local anesthesia alone, without general anesthesia or intravenous sedation, in adolescents and adults. In children, this technique can reduce the need for postoperative opioids. We describe this novel analgesic approach to decrease opioid requirements and minimiz

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Arindra, Pingky Krisna, Prihartiningsih Prihartiningsih, and Bambang Dwi Rahardjo. "Penatalaksanaan Repair Palatoplasty dengan Teknik Furlow Double Opposing Z Plasty." Majalah Kedokteran Gigi Indonesia 1, no. 1 (2015): 115. http://dx.doi.org/10.22146/majkedgiind.8856.

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Kasus bibir dan lelangit sumbing merupakan salah satu kelainan deformitas yang sering terjadi. Keadaan klinis bervariasi mulai dari kasus sumbing tidak komplit sampai dengan komplit. Keadaan klinis dengan lebar celah yang bervariasi membutuhkan teknik pembedahan yang tepat. Pasien-pasien dengan bibir dan atau lelangit sumbing mungkinsebelumnya telah menjalani beberapa intervensi pembedahan, sehingga sering memerlukan koreksi lebih lanjut untuk memperbaiki hasil operasi sebelumnya. Pasien anak laki-laki usia 4 tahun 7 bulan mengeluhkan masih terdapatnya celah di lelangit. Pasien didiagnosis den

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Isaac, Kathryn V., Ingrid M. Ganske, Stephen A. Rottgers, So Young Lim, and John B. Mulliken. "Cleft Lip and Palate in CHARGE Syndrome." Cleft Palate-Craniofacial Journal 55, no. 3 (2017): 342–47. http://dx.doi.org/10.1177/1055665617738994.

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Objective: Infants with syndromic cleft lip and/or cleft palate (CL/P) often require more complex care than their nonsyndromic counterparts. Our purpose was to (1) determine the prevalence of CL/P in patients with CHARGE syndrome and (2) highlight factors that affect management in this subset of children. Design: This is a retrospective review from 1998 to 2016. Patients: Patients with CHARGE syndrome were diagnosed clinically and genetically. Main Outcomes Measures: Prevalence of CL/P was determined and clinical details tabulated: phenotypic anomalies, cleft types, operative treatment, and re

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Gutierrez Vargas, Maria Camila, and Henry Ostos Alfonso. "Caracterización de la población pediátrica con labio y/o paladar hendido en un hospital regional del sur colombiano." Revista Repertorio de Medicina y Cirugía 34, no. 1 (2025): 40–45. https://doi.org/10.31260/repertmedcir.01217372.1522.

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Introduction: cleft lip (CL), and cleft palate (CP) or combined cleft lip and palate (CLP) are a group of congenital anomalies caused by the failure of fusion of embryonic tissues. Objective: to characterize the pediatric population with cleft lip and/or palate. Materials and methods: a retrospective cross-sectional observational descriptive study conducted during 2022 in a regional hospital. Results: 42 patients were included, predominantly females, the majority were non-syndromic, two died due to other congenital malformations and molecular detections such as the NOTCH1 variant and Xq26.32 a

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Thapa, Ajay Singh, and Rajesh Kumar Yadav. "Cleft Lip and Palate Surgery: Prevalance of Intraoperative Airway Complications in a Tertiary Center in Nepal." Birat Journal of Health Sciences 4, no. 3 (2020): 805–8. http://dx.doi.org/10.3126/bjhs.v4i3.27021.

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Introduction: Cleft lip and palate is one of the most common congenital malformations. Different syndromes have been described in association with cleft lip and palate, some of which have considerable anesthetic implications, and many involve potential airway problems. Objective: This study aimed to find the incidence of airway complications during cleft surgeries. Methods: The descriptive cross sectional study was conducted in College of Medical Sciences and Teaching Hospital, Bharatpur, Chitwan, Nepal over a period of one year from March 2017 toFebruary2018. All the 146 patients

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Srivastava, Maya Devi. "Persistent Severe Combined Immunodeficiency with Absent Trecs Secondary to Thymectomy for TOF Repair in Early Infancy." Journal of Allergy and Clinical Immunology 139, no. 2 (2017): AB108. http://dx.doi.org/10.1016/j.jaci.2016.12.349.

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Moslem, Dr Lt Col Mir Hasan Md, Dr Brig Gen (Rtd) Nurunnahar Fatema Begum, Dr Col Ferdousur Rahman Sarker, et al. "Outcome of Management of Tetralogy of Fallot in a Cardiac Center of a Tertiary Care Hospital in Bangladesh." Scholars Journal of Applied Medical Sciences 11, no. 04 (2023): 710–17. http://dx.doi.org/10.36347/sjams.2023.v11i04.007.

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Background: Congenital heart diseases (CHD) represent one of the major groups of birth defects and make up approximately 1% of human malformations. Incidence of congenital heart disease is 8-10/1000 live births. The incidence is higher in premature infants. In Bangladesh incidence of congenital heart diseases was found up to 25/1000 live birth in a one year study conducted in CMH Dhaka. Congenital cyanotic heart disease accounts for less than 25% of total congenital cardiac defects. In TOF the lungs are under-perfused as blood shunts from right to left bypassing the lungs. TOF constitutes 5-7%

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Peltomäki, Timo, Bruno L. Vendittelli, Barry H. Grayson, Court B. Cutting, and Lawrence E. Brecht. "Associations between Severity of Clefting and Maxillary Growth in Patients with Unilateral Cleft Lip and Palate Treated with Infant Orthopedics." Cleft Palate-Craniofacial Journal 38, no. 6 (2001): 582–86. http://dx.doi.org/10.1597/1545-1569_2001_038_0582_absoca_2.0.co_2.

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Objective: The purpose of this study was to examine possible associations between severity of clefting in infants and maxillary growth in children with complete unilateral cleft lip and palate. Design: This was a retrospective study of measurements made on infant maxillary study casts and maxillary cephalometric variables obtained at 5 to 6 years of follow-up. Setting: The study was performed at the Institute of Reconstructive Plastic Surgery of New York University Medical Center, New York, New York. Patients: Twenty-four consecutive nonsyndromic unilateral complete cleft lip and palate patien

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Sarker, Md Selim, Mohammad Rezaul Karim, Mohammad Emran, Md Mosaddak Akbar, and Nur E. Dilara Islam. "Evaluation of Anaesthetic Challenges in Primary Cleft Lip and Palate Surgeries in a Single Center Study." Annals of International Medical and Dental Research 9, no. 2 (2023): 303–9. http://dx.doi.org/10.53339/aimdr.2023.9.41.

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Background: One of the most prevalent congenital malformations and the most frequent craniofacial defects in children is cleft lip and palate. The aim of the study was to investigate the anaesthetic procedures employed and to determine the challenges and postoperative complications associated with cleft lip and palate surgery. Material Methods: A retrospective review of the anaesthetic procedures carried out from January 2022 to December 2022 at the Dhaka Dental College and Hospital. The hospital records were reviewed in order to learn about every occurrence of orofacial cleft surgery. In this

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Abramson, David L., Eileen M. Marrinan, and John B. Mulliken. "Robin Sequence: Obstructive Sleep Apnea following Pharyngeal Flap." Cleft Palate-Craniofacial Journal 34, no. 3 (1997): 256–60. http://dx.doi.org/10.1597/1545-1569_1997_034_0256_rsosaf_2.3.co_2.

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Objective We reviewed 24 children with Robin sequence who underwent cleft palate repair. Method All patients were 5 years of age or older at the time of review, allowing for accurate assessment of speech in relation to velopharyngeal function. All infants had palatal closure between 9 and 14 months of age, either V-Y repair (n = 16) or von Langenbeck repair (n = 8). Results Only 1 of 16 children who had V-Y repair had borderline velopharyngeal dysfunction (VPD). For reasons that are unclear, in the von Langenbeck repair group, six of eight children had VPD, and four of six underwent pharyngeal

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Hodges, Andrew M. "Combined early cleft lip and palate repair in children under 10 months – a series of 106 patients." Journal of Plastic, Reconstructive & Aesthetic Surgery 63, no. 11 (2010): 1813–19. http://dx.doi.org/10.1016/j.bjps.2009.10.033.

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Karki, Shambhu Bahadur, LK Rajbanshi, Batsalya Ariyal, and K. Shrestha. "Anaesthesia for Cleft Lip and Palate Surgery: Study from a Hospital of Eastern Nepal." Birat Journal of Health Sciences 2, no. 1 (2017): 127–33. http://dx.doi.org/10.3126/bjhs.v2i1.17288.

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IntroductionCleft lip and palate deformity is the most common congenital birth defect caused by complex genetic and environmental factors. Pre-operative management of these patients is always challenging and anesthesia has a great role for the surgery.ObjectiveThe aim of this study is to evaluate the outcomes including pre-operative election of cases, intra-operative and post-operative complications in pediatric patients.MethodologyThis is retrospective study conducted on cleft lip and palate repair patients between the ages of 3 months to 12 years, operated under general anesthesia during las

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Smarius, B. J. A., C. H. A. L. Guillaume, J. Slegers, A. B. Mink van der Molen, and C. C. Breugem. "Surgical management in submucous cleft palate patients." Clinical Oral Investigations 25, no. 6 (2021): 3893–903. http://dx.doi.org/10.1007/s00784-020-03719-1.

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Abstract Objectives The submucous cleft palate (SMCP) is considered to be the most subtle type of cleft palate. Early detection is important to allow on time intervention by speech therapy and/or surgical repair before the children already develop compensatory speech mechanisms. The purpose of this study was to investigate at what time children with a SMCP present, to determine when children are operated, and to analyze the postoperative outcomes for in SMCP children. Patient and methods Medical records from 766 individuals registered in the cleft registry in the Wilhelmina’s Children’s’ Hospi

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Ephraim, Samson K., Cecilia Protas, and Francis Tegete. "Surgical Management of Oro-Facial Clefts at a Tertiary Care Hospital in a Resource-Limited Setting: A Tanzanian Experience." EAS Journal of Medicine and Surgery 5, no. 10 (2023): 210–22. http://dx.doi.org/10.36349/easjms.2023.v05i10.007.

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Background: Orofacial clefts are the most common craniofacial anomalies in most parts of the world and its management remains a challenge to otorhinolaryngology, plastic/reconstructive, oral and maxillofacial surgeons practicing in resource limited countries. There is limited data on surgical management of these birth defects in Tanzania and Bugando Medical Centre (BMC) in particular. This study aimed to describe our own experience regarding the surgical management of orofacial clefts at BMC, a tertiary care hospital in Tanzania. Methods: This was a cross sectional study involving all children

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Elsherbiny, Ahmed, Ahmed Gelany, Ahmed S. Mazeed, et al. "Buccinator Re-Repair (Bs + Re: IVVP): A Combined Procedure to Maximize the Palate Form and Function in Difficult VPI Cases." Cleft Palate-Craniofacial Journal 57, no. 5 (2020): 543–51. http://dx.doi.org/10.1177/1055665619900621.

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Objectives: To assess the outcome of a modified buccinator flaps’ palatal lengthening combined with radical intravelar veloplasty (Bs + Re: IVVP) for the management of postpalatoplasty velopharyngeal incompetence and report the functional and structural changes occurring in the palate. Design: Prospective cohort study of consecutive cleft patients presenting with velopharyngeal incompetence and managed by buccinator re-repair procedure. Blind assessment of randomized recordings of speech and evaluation of velar form and function with nasoendoscopy and lateral videofluoroscopy were done. Patien

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Bartholomew, Ryan, Joseph Zenga, Derrick Lin, Daniel Deschler, and Jeremy Richmon. "Tip-on-Tip Scapular (TOTS) Flap for Reconstruction of Combined Palatectomy and Rhinectomy Defects." Facial Plastic Surgery 34, no. 04 (2018): 389–93. http://dx.doi.org/10.1055/s-0038-1666784.

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AbstractCombination anterior palatectomy and rhinectomy defects result in complete loss of midface and nasal support and present a significant reconstructive challenge. A novel use of the scapular tip free flap—the tip-on-tip scapula flap—was developed to provide both palatal repair and restoration of intrinsic nasal support. The scapular tip bone is split into a large proximal segment for the anterior palate and a smaller distal bone segment for nasal framework reconstruction. Two patients undergoing reconstruction of both total palatectomy and partial rhinectomy defects at a single academic

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Eghbali, Ahmad, and Bahram Khoram. "Comparing the effects of ropivacaine and lidocaine associated with epinephrine on the heart rate, blood pressure, and amount of bleeding in patients candidate for cleft palate repair: A randomized clinical trial." Journal of Shahrekord University of Medical Sciences 24, no. 3 (2022): 111–16. http://dx.doi.org/10.34172/jsums.2022.18.

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Background and aims: This study was conducted to compare the effects of two compounds ropivacaine and lidocaine associated with epinephrine on the heart rate, blood pressure, and bleeding rate in children undergoing general anesthesia for the cleft palate repair surgery. Methods: In this study, 30 children candidates for cleft palate surgery who were referred to Mofid Children’s Hospital, affiliated with Shahid Beheshti University of Medical Sciences in 2021, were included by using the convenience sampling method. The patients were randomly divided into two groups. Group 1 was treated with rop

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Luo, Ke, Jun-Mei Xu, Lin Cao, and Ju Gao. "Effect of dexmedetomidine combined with sufentanil on preventing emergence agitation in children receiving sevoflurane anesthesia for cleft palate repair surgery." Experimental and Therapeutic Medicine 14, no. 2 (2017): 1775–82. http://dx.doi.org/10.3892/etm.2017.4660.

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Kolisetty, Pavan Venkateswar, Sheikh Sarfraz Ali, and Indrajith K. Sudhy. "Experience with double transposition flaps and intravelar veloplasty for closure of wide cleft palates." Journal of Cleft Lip Palate and Craniofacial Anomalies 11, no. 1 (2024): 16–20. http://dx.doi.org/10.4103/jclpca.jclpca_26_23.

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ABSTRACT Background: Repairing a wide cleft palate is a challenging task for surgeons. The goals of cleft palate repair such as achieving anatomical closure of the defect, complete velopharyngeal closure, speech development, and to minimize dentoalveolar anomalies are difficult to achieve in wide and massive cleft palates. Several methods have been described for the same. We performed double transposition flaps combined with intravelar veloplasty in our patients. In this article, we share our experience with the same. Materials and Methods: We reviewed 9 cases, in which double transposition fl

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Rizzo, Maria Ida, Nefer Fallico, Annapina Palmieri, et al. "Rhinomanometry evidence in children treated by Furlow’s palatoplasty for velopharyngeal insufficiency correlated to cleft palate." Il Giornale di Chirurgia - Journal of the Italian Association of Hospital Surgeons 44, no. 3 (2024): e49. http://dx.doi.org/10.1097/ia9.0000000000000049.

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Background: Speech surgery outcomes for velopharyngeal insufficiency (VPI) are difficult to quantify. We investigated the correlation between objective measurements of nasal emission and speech assessment ratings in children undergoing Furlow palatoplasty for the treatment of cleft-related VPI. Methods: A total of 20 patients with VPI after primary cleft palate repair were recruited for Furlow’s palatoplasty. All participants completed rhinomanometry (RM) and speech evaluation scored by two blinded speech-language pathologists. Pre- and postoperative results were compared using the paired t te

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Lupi, Ettore, Alessandra Ciccozzi, Roberto Becelli, Mario Mannino, Sara Bernardi, and Filippo Giovannetti. "Surgical Management of Oro-Nasal Communication in Cocaine-Induced Lesions: Temporalis Muscle Flap with Le Fort I Osteotomy." Journal of Clinical Medicine 14, no. 6 (2025): 2033. https://doi.org/10.3390/jcm14062033.

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Background: Cocaine is a recreational drug known for its negative impact on health and social and economic life. One of the complications for cocaine abusers is cocaine-induced midline destructive lesion (CIMDL) syndrome, which includes the extensive destruction of the osteocartilaginous structures of the nose, the sinus, and the palate. Methods: Here, we describe three cases of the surgical management of CIMDL using a temporalis muscle flap combined with a Le Fort I osteotomy, which allows sufficient space for the muscle to settle. Results: The addition of the osteotomy allowed better handlin

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Ayyoub, Sam, Rishab Parapperi, Ubayd Isa, Mahek Mumtaz, and Faisal R. Jahangiri. "The Advantages of Using Intraoperative Neurophysiological Monitoring in Hip Surgeries: A Meta-Analysis." J of Neurophysiological Monitoring 2, no. 2 (2024): 46–59. https://doi.org/10.5281/zenodo.11152081.

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Various hip surgeries place peripheral nerves at risk of injury, such as those occurring during total hip arthroplasty, arthroscopic hip repair, and periacetabular osteotomy. In total hip arthroplasty, intraoperative neurophysiological monitoring (IONM) is focused on the sciatic nerve, which is particularly vulnerable due to its proximity to the surgical site. During arthroscopic hip repair, careful attention is paid to monitoring the femoral and lateral femoral cutaneous nerves to prevent traction and compression injuries. In periacetabular osteotomy, which involves cutting and realigning the

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Murugan, Aparna, Manikandhan Ramanathan, Keerthana Ponvel, and Herman F. Sailer. "Evaluation of the Efficacy of Platelet-rich Fibrin with an Osseous Graft in Cleft Alveolar Patients: A Clinical Study." Oral Health Research and Clinical Evidence 2, no. 1 (2025): 24–30. https://doi.org/10.4103/orcl.orcl_6_25.

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Objective: The alveolar cleft is a bony defect found in 75% of patients with cleft lip and palate. Alveolar cleft repair uses autogenous, allogenic, and alloplastic materials, with autologous grafts widely accepted. Various techniques and materials, such as platelet-rich fibrin (PRF), platelet-rich plasma, recombinant human platelet-derived growth factor, and bone morphogenetic protein-2 and 7, have been used to retain bone at recipient sites. Materials and Methods: The study assessed the effectiveness of PRF combined with osseous graft in enhancing bone and soft-tissue healing in alveolar cle

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Morota, Nobuhito, Satoshi Ihara, Hideki Ogiwara, Kenichi Usami, Ikkei Tamada, and Tsuyoshi Kaneko. "Basal encephalocele: surgical strategy and functional outcomes in the Tokyo experience." Journal of Neurosurgery: Pediatrics 27, no. 1 (2021): 69–78. http://dx.doi.org/10.3171/2020.6.peds20315.

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OBJECTIVEThe basal encephalocele (BEC) is the rarest form of encephalocele, with an incidence of about 1/35,000 live births. The incidence of its subtype, sphenoidal BEC, is even lower at about 1/700,000 live births. The aim of this study was to propose the optimal surgical approach to repairing BEC, with special attention to the reconstruction of the skull base bone defect.METHODSFourteen consecutive pediatric patients with BEC who underwent surgical repair between March 2004 and March 2020 (10 boys and 4 girls, age 25 days to 7 years, median age 4 months) were enrolled. The follow-up period

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Kobets, Andrew J., Richard J. Redett, Jonathan M. Walsh, Joseph Lopez, Melike Guryildirim, and Alan R. Cohen. "Repair of Giant Anterior Skull Base Encephalocele Containing Intralesional Eloquent Brain: Technical Note." Operative Neurosurgery 21, no. 2 (2021): 73–80. http://dx.doi.org/10.1093/ons/opab088.

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Abstract BACKGROUND Encephaloceles are herniations of intracranial neural tissue and meninges through defects in the skull. Basal encephaloceles are rare anterior skull base defects incident in 1 in 35,000 live births. Sphenoethmoidal encephaloceles are even more uncommon, with an incidence of 1 in 700,000 live births. Anterior skull base encephaloceles may be life-threatening in infants, presenting as airway obstruction and respiratory compromise. They can also present with cerebrospinal fluid (CSF) rhinorrhea, purulent nasal drainage, or meningitis. OBJECTIVE To report a novel technique for

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Kontos, Hans Friede, Henriques Cint, Konstantinos. "Maxillary development and dental occlusion in patients with unilateral cleft lip and palate after combined velar closure and lip-nose repair at different ages." Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 35, no. 4 (2001): 377–86. http://dx.doi.org/10.1080/028443101317149345.

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Chevignard, Mathilde, Kim Bull, James Holt, et al. "QOL-17. BIOLOGICAL CORRELATES OF QUALITY OF SURVIVAL AND NEUROCOGNITIVE OUTCOMES IN MEDULLOBLASTOMA; A META-ANALYSIS OF THE SIOP-UKCCSG-PNET3 AND HIT-SIOP-PNET4 TRIALS." Neuro-Oncology 22, Supplement_3 (2020): iii434. http://dx.doi.org/10.1093/neuonc/noaa222.679.

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Abstract Relationships between biological factors (genetic, tumour molecular subgroup) and neurocognitive/Quality of Survival (QoS) outcomes in medulloblastoma survivors are emerging, based on studies of limited retrospective cohorts. Integrated investigations of the medulloblastoma late-effects pathway (considering biological, clinical and treatment factors), using larger clinically-controlled cohorts, are now essential to determine their independent significance and potential for clinical application. In a combined cohort of SIOP-UKCCSG-PNET3 and HIT-SIOP-PNET4 patients (n=150), molecular su

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Cho, Byung Chae. "Unilateral Complete Cleft Lip and Palate Repair Using Lip Adhesion Combined with a Passive Intraoral Alveolar Molding Appliance: Surgical Results and the Effect on the Maxillary Alveolar Arch." Plastic and Reconstructive Surgery 117, no. 5 (2006): 1510–29. http://dx.doi.org/10.1097/01.prs.0000209467.98050.20.

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Filip, Charles, Michael Matzen, Ingegerd Aagenses, et al. "Speech and Magnetic Resonance Imaging Results following Autologous Fat Transplantation to the Velopharynx in Patients with Velopharyngeal Insufficiency." Cleft Palate-Craniofacial Journal 48, no. 6 (2011): 708–16. http://dx.doi.org/10.1597/09-161.

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Objective To measure velopharyngeal closure with magnetic resonance imaging (MRI) and to evaluate speech when treating velopharyngeal insufficiency (VPI) with autologous fat transplantation to the velopharynx. Patients Nine patients were recruited. Six patients had undergone cleft palate repair and subsequently developed VPI. Three were noncleft patients of which one had developed VPI after nasopharyngeal cancer treatment; another patient had developed VPI after combined adenotonsillectomy, and a third patient had VPI of unknown etiology. Main outcome measure Preoperative and 1-year postoperat

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Emanuel, Hina, Amee Revana, Tue Te, and Kevin Kaplan. "830 Combined Phototherapy and Melatonin for treatment of Circadian Rhythm Disorder in a Patient with Cornelia de Lange Syndrome." Sleep 44, Supplement_2 (2021): A323—A324. http://dx.doi.org/10.1093/sleep/zsab072.827.

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Abstract Introduction Cornelia de Lange syndrome (CdLS) is a rare genetic disorder characterized by variable physical, cognitive, and behavioral characteristics. Sleep disturbances have been frequently reported in CdLS including insomnia, sleep-disordered breathing, intrinsic sleep disorders, and circadian rhythm disorders (CRDs). The characterization and prevalence of CRDs in CdLS remain ill- defined. We report a case of a 13-year-old female with CdLS presenting with advanced sleep wake phase disorder (ASWPD). Report of case(s) A 13-year-old female with a past medical history of CdLS, develop

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Ferry, Andrew M., Han Zhuang Beh, Rami P. Dibbs, et al. "Impact of COVID-19 on Cleft Surgical Care." FACE 2, no. 1 (2021): 6–12. http://dx.doi.org/10.1177/2732501621996009.

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Background: Coronavirus disease 2019 (COVID-19) has greatly impacted pediatric healthcare facilities throughout the United States due to widespread case rescheduling and the implementation of supplementary COVID-19 perioperative protocols. To our knowledge, no studies have investigated the impact of COVID-19 on case volume, surgical timing, or operational aspects of cleft surgical procedures. The aim of this study is to investigate the impact that COVID-19 has had on cleft surgical care at our institution. Methods: A retrospective study comparing cleft surgical care in 2019 (the pre-pandemic c

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Pinheiro, Carla C. G., Alessander Leyendecker Junior, Daniela Y. S. Tanikawa, José Ricardo Muniz Ferreira, Reza Jarrahy, and Daniela F. Bueno. "Is There a Noninvasive Source of MSCs Isolated with GMP Methods with Better Osteogenic Potential?" Stem Cells International 2019 (November 6, 2019): 1–14. http://dx.doi.org/10.1155/2019/7951696.

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Background. A new trend in the treatment for alveolar clefts in patients with cleft lip and palate involves the use of bone tissue engineering strategies to reduce or eliminate the morbidity associated with autologous bone grafting. The use of mesenchymal stem cells—autologous cells obtained from tissues such as bone marrow and fat—combined with various biomaterials has been proposed as a viable option for use in cleft patients. However, invasive procedures are necessary to obtain the mesenchymal stem cells from these two sources. To eliminate donor site morbidity, noninvasive stem cell source

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Fernandes Cabral, David T., Georgios A. Zenonos, Juan C. Fernandez-Miranda, Eric W. Wang, and Paul A. Gardner. "Iatrogenic seeding of skull base chordoma following endoscopic endonasal surgery." Journal of Neurosurgery 129, no. 4 (2018): 947–53. http://dx.doi.org/10.3171/2017.6.jns17111.

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OBJECTIVEIatrogenic tumor seeding after open surgery for chordoma has been well described in the literature. The incidence and particularities related to endoscopic endonasal surgery (EES) have not been defined.METHODSThe authors retrospectively reviewed their experience with EES for clival chordoma, focusing on cases with iatrogenic seeding. The clinical, radiographic, pathological, and molecular characterization data were reviewed.RESULTSAmong 173 EESs performed for clival chordomas at the authors’ institution between April 2003 and May 2016, 2 cases complicated by iatrogenic seeding (incide

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Kishanrao, Suresh. "Managing Common Ear Problems by Primary Care Providers." Clinical Medical Reviews and Reports 6, no. 2 (2024): 01–05. https://doi.org/10.31579/2690-8794/198.

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Ear ailments (Otitis Media) are a major public health problem in India especially among children. Middle ear inflammation is a spectrum of conditions known as acute otitis media (AOM), Otitis media with effusion (OEM or glue ear) Chronic suppurative otitis media (CSOM) and Cerumen blockage. Acute otitis media a disease of infancy and childhood defined by the presence of inflammation and at least one of the signs of acute illness namely earache, fever, ear discharge, pulling ear etc is a leading cause of childhood morbidity and antibiotic prescriptions in India. It is second only to acute upper

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