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Journal articles on the topic 'Comedogenicity'

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1

Katoulis, A. C., E. M. Kakepis, H. Kintziou, M. E. Kakepis, and N. G. Stavrianeas. "Comedogenicity of cosmetics: a review." Journal of the European Academy of Dermatology and Venereology 7, no. 2 (1996): 115–19. http://dx.doi.org/10.1111/j.1468-3083.1996.tb00606.x.

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2

Tucker, S. B. "Development of an objective comedogenicity assay." Archives of Dermatology 122, no. 6 (1986): 660–65. http://dx.doi.org/10.1001/archderm.122.6.660.

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3

Tucker, Stephen B. "Development of an Objective Comedogenicity Assay." Archives of Dermatology 122, no. 6 (1986): 660. http://dx.doi.org/10.1001/archderm.1986.01660180066016.

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4

Nguyen, Shawn H., Thao P. Dang, and Howard I. Maibach. "Comedogenicity in Rabbit: Some Cosmetic Ingredients/Vehicles." Cutaneous and Ocular Toxicology 26, no. 4 (2007): 287–92. http://dx.doi.org/10.1080/15569520701555383.

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5

Draelos, Zoe Diana, and Joseph C. DiNardo. "A re-evaluation of the comedogenicity concept." Journal of the American Academy of Dermatology 54, no. 3 (2006): 507–12. http://dx.doi.org/10.1016/j.jaad.2005.11.1058.

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6

Myung, Ki Bum. "Assessment of Comedogenicity of Cosmetics in Humans and Rabbits." Ewha Medical Journal 12, no. 4 (1989): 335. http://dx.doi.org/10.12771/emj.1989.12.4.335.

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7

Maarouf, Melody, Chantal Saberian, and Vivian Y. Shi. "Myths, Truths, and Clinical Relevance of Comedogenicity Product Labeling." JAMA Dermatology 154, no. 10 (2018): 1131. http://dx.doi.org/10.1001/jamadermatol.2018.1741.

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8

CHIBA, Katsuyoshi, Kazuhiko YOSHIZAWA, Ikuyo MAKINO, Koji KAWAKAMI, and Masaharu ONOUE. "Comedogenicity of squalene monohydroperoxide in the skin after topical application." Journal of Toxicological Sciences 25, no. 2 (2000): 77–83. http://dx.doi.org/10.2131/jts.25.77.

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9

Sharmina Huq, Tasmia Zaman Mim, Abdullah Al Noman, Snigdha Malabeka, and Nashim Ahmed. "Munir Rashid Chowdhury." World Journal of Advanced Research and Reviews 24, no. 3 (2024): 2070–77. https://doi.org/10.30574/wjarr.2024.24.3.3840.

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Background: Acne vulgaris is a common dermatological condition influenced by factors such as pore blockage, excessive sebum production, and inflammation. This study evaluates the comedogenicity, skin tolerability, and functional benefits of Siodil acne treatment products, including Sebi Gel, Sebi Serum, Sebi Cleanser, and ATO Gel. Methods: A total of 26 participants aged 18–40 years underwent a 28-day open-label trial to assess the impact of Siodil products on pore blockage, skin hydration, and acne reduction. Comedogenicity was scored using a standardized acne grading scale, and patch tests w
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10

Munir, Rashid Chowdhury, Huq Sharmina, Zaman Mim Tasmia, Al Noman Abdullah, Malabeka Snigdha, and Ahmed Nashim. "Assessment of comedogenicity and skin reactions to siodil acne treatment products: A preliminary clinical trial." World Journal of Advanced Research and Reviews 24, no. 3 (2024): 2070–77. https://doi.org/10.5281/zenodo.15209182.

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<strong>Background:&nbsp;</strong>Acne vulgaris is a common dermatological condition influenced by factors such as pore blockage, excessive sebum production, and inflammation. This study evaluates the comedogenicity, skin tolerability, and functional benefits of Siodil acne treatment products, including Sebi Gel, Sebi Serum, Sebi Cleanser, and ATO Gel. <strong>Methods:&nbsp;</strong>A total of 26 participants aged 18&ndash;40 years underwent a 28-day open-label trial to assess the impact of Siodil products on pore blockage, skin hydration, and acne reduction. Comedogenicity was scored using a
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11

Kligman, Albert M. "Improved Procedure for Assessing Acnegenicity (Comedogenicity) in the Rabbit Ear Model." Journal of Toxicology: Cutaneous and Ocular Toxicology 8, no. 4 (1989): 395–410. http://dx.doi.org/10.3109/15569528909062944.

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12

Arenas, Daniel, Korkunda Svitlana, Andres Eloy Soto, Jorge López Berroa, and Daniela Marín Rivera. "Efficacy and Tolerance Evaluation of pbserum smartker Equilibrium Professional." Latin american journal of clinical sciences and medical technology 6, no. 1 (2024): 167–73. http://dx.doi.org/10.34141/ljcs1720359.

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Introduction. Skin acts as a complete barrier protecting against external aggressions and keeps the body’s internal balance. The loss of its firmness and elasticity is a complex process associated with cutaneous aging, which implies intrinsic and extrinsic factors that promote changes in the dermis, epidermis, and abnormal pigmentation. In recent years, treatments for improving skin health and beauty have advanced significantly, which has raised great interest in the related technology. Objective. To evaluate the efficacy and tolerability of pbserum smartker Equilibrium Professional in terms o
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13

Sidou, F., N. Kerrouche, and P. Soto. "P95 Comedogenicity and cosmetic acceptability of a new UVA/UVB protection cream." Melanoma Research 20 (June 2010): e83. http://dx.doi.org/10.1097/01.cmr.0000382929.49058.04.

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14

Baek, J. H., S. M. Ahn, K. M. Choi, M. K. Jung, M. K. Shin, and J. S. Koh. "Analysis of comedone, sebum and porphyrin on the face and body for comedogenicity assay." Skin Research and Technology 22, no. 2 (2015): 164–69. http://dx.doi.org/10.1111/srt.12244.

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15

J, N. Divya, Joydeep Roy, Bhaskar Gupta, Arup Paul, and Shromona Kar. "Petroleum Jelly: A Brief Review of its History, Uses and Safety." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 914–21. https://doi.org/10.5281/zenodo.14052733.

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Petrolatum, commonly known as petroleum jelly, is a versatile topical agent widely used in dermatology. Despite its popularity, misconceptions persist about this dermatological staple. This review explores petrolatum&rsquo;s history, manufacturing process, and biological properties that make it an excellent moisturizer. It addresses concerns about flammability, allergenicity, and comedogenicity, dispelling myths about its use near oxygen and its potential to cause acne. Petrolatum&rsquo;s diverse applications in dermatology include serving as a patch test instrument, a vehicle for medicated oi
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16

Waranuch, Neti, Sutthinee Wisutthathum, Supaporn Tuanthai, et al. "Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial." Contemporary Clinical Trials Communications 23 (September 2021): 100834. http://dx.doi.org/10.1016/j.conctc.2021.100834.

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17

Gala, Monil Yogesh Neena, Snehal Sameer Muchhala, Sujeet Narayan Charugulla, et al. "Evaluation of comedogenic potential of a moisturizer venusia max lotion (PAMA free)." IP Indian Journal of Clinical and Experimental Dermatology 8, no. 1 (2022): 28–31. http://dx.doi.org/10.18231/j.ijced.2022.006.

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: Being commonly used skin care products, comedogenic potential of moisturizers should be assessed. : The aim of the study was to evaluate the comedogenic potential of a moisturizer Venusia Max Lotion (paraben-, alcohol-, mineral oil-, animal origin-(PAMA) free) when applied topically to the skin compared to the controls. : Double-blind, single-center, comparative study conducted at private institute in Mumbai, India: Approximately 0.025 gm of the test product and 0.025 ml of positive control (coconut oil) and negative control (glycerin) were applied and occluded under a patch on the upper bac
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18

Bhuvaneswari, V. S., and R. S. Chandan. "REVIEW ON SAFETY ASSESSMENT OF A COSMETIC PRODUCT." International Journal of Current Pharmaceutical Research 10, no. 3 (2018): 1. http://dx.doi.org/10.22159/ijcpr.2018v10i3.27333.

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Cosmetics can be defined as, “substances which are intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body’s structure or functions” according to USFDA. This review encompasses a brief description of the process of safety assessment of a cosmetic product. There is no significant systemic absorption of cosmetics by penetration through skin, but some products are intended to apply on the mucous membranes or skin surrounding the mucous membranes which may result in significant systemic absorption on conti
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19

Andersen, F. Alan. "Final Safety Assessment for PCA and Sodium PCA." International Journal of Toxicology 18, no. 2_suppl (1999): 25–34. http://dx.doi.org/10.1177/109158189901800206.

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PCA is the cosmetic ingredient term used for the cyclic organic compound known commonly as pyroglutamic acid. Sodium PCA is the sodium salt of PCA. Both are used as hair and skin conditioning agents. These ingredients are recommended to be used in a concentration range of 0.2-4%. One optical isomer of PCA (the L form) is a naturally occurring component of mammalian tissue. PCA applied to the skin is absorbed to a limited extent. Absorption is in addition to PCA already present in the skin. In short-term and subchronic studies in several animal species, findings were unremarkable except for neu
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20

Johnson, Wilbur. "Final Report on the Safety Assessment of Propylene Glycol (PG) Dicaprylate, PG Dicaprylate/Dicaprate, PG Dicocoate, PG Dipelargonate, PG Isostearate, PG Laurate, PG Myristate, PG Oleate, PG Oleate SE, PG Dioleate, PG Dicaprate, PG Diisostearate, and PG Dilaurate." International Journal of Toxicology 18, no. 2_suppl (1999): 35–52. http://dx.doi.org/10.1177/109158189901800207.

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The Propylene Glycol Dicaprylate family of ingredients includes several esters and diesters of Propylene Glycol and fatty acids. These ingredients are used in cosmetic formulations as skin conditioning agents, viscosity increasing agents, and surfactants. Two skin irritation studies (minimal to no irritation) and a comedogenicity study (insignificant comedogen) on Propylene Glycol Dicaprylate/Dicaprate and a skin irritation study (slight) and an acute oral toxicity study (nontoxic) on Propylene Glycol Laurate were available. Available data were also found indicating that Propylene Glycol Dicap
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21

Aich, Biswajit, Gauri Debashish Dhanaki, Arti Sanghavi, Snehal Muchhala, Sagar Katare, and Bhavesh Kotak. "Evaluation of comedogenic potential of a ceramide-based moisturizer (lotion/cream): A prospective, randomized, double-blind, parallel-group comparative study." Cosmoderma 5 (February 22, 2025): 28. https://doi.org/10.25259/csdm_203_2024.

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Objectives Comedogenicity is a crucial consideration for cosmetic preparations. While most of the ingredients used in moisturizers may have the ability to cause comedones, the study was done to assess the non-comedogenic potential of test products (Venusia CeraPlus Moisturizers). The primary objective of the study was to evaluate the comedogenic potential of the test products using light microscopy. Materials and Methods This was a prospective, randomized, double-blinded, positive- and negative-controlled, two-cohort study to evaluate the comedogenic potential of Venusia CeraPlus moisturizers.
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22

Lanigan, Rebecca S. "Final Report On the Safety Assessment of Iodopropynyl Butylcarbamate (IPBC)." International Journal of Toxicology 17, no. 5_suppl (1998): 1–37. http://dx.doi.org/10.1177/109158189801700503.

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Iodopropynyl Butylcarbamate (IPBC) functions as a preservative in a wide variety of cosmetic formulations. Although concentrations as high as 0.1% have been reported, most applications appear to require this preservative at less than 0.0125%. IPBC readily penetrates through the skin. The average acute oral LD50 in rats is 1.47 g/kg. Rats fed IPBC for 4 weeks had increased liver weights and decreased plasma cholinesterase activity, and rats fed IPBC for 13 weeks had transient behavior alteration, increased liver weights, hepatocyte enlargement, stomach lesions, and decreased weight gain. Rats a
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23

Gala, Monil Yogesh Neena, Snehal Sameer Muchhala, Sujeet Narayan Charugulla, et al. "Evaluation of comedogenic potential of a paraben-free plant-based butter moisturizing cream: A double-blind, comparative study." Cosmoderma 1 (October 7, 2021): 52. http://dx.doi.org/10.25259/csdm_53_2021.

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Objectives: Comedogenicity is a critical factor in making of cosmetics and skin care products. The term “acne cosmetica” was coined to link the relationship between female acne to the use of cosmetic formulations, stating that the ingredients used in the cosmetic formulations have the potential to evoke a comedogenic response or produce comedones. Therefore, it is important that a skin care product is non-comedogenic and efficacious at the same time. The main objective of this study is to evaluate the comedogenic potential of the test product (Venusia Max Cream – paraben free) when applied top
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24

Bobok, N. M. "Should skincare products from different brands be combined for a systematic routine? (Review)." Ukrainian Journal of Dermatology, Venerology, Cosmetology, no. 1 (March 28, 2025): 32–41. https://doi.org/10.30978/ujdvk2025-1-32.

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The modern cosmetics market has a significant number of companies offering various skin, hair and body care products. However, the question of whether it is worth combining products from various brands or sticking to a single product line remains relevant. Objective — to summarize and compare information on the use of skincare products from a single brand versus multiple ones. Materials and methods. Relevant sources on the systematic use of skin care products were searched online using systemic, bibliosemantic, and analytical methods. Inclusion criteria were meta-analyses, literature reviews,
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25

Abel Francis, Abel Francis, and Anitta Shojan. "Comedogenicity of Oils." International Journal of Contemporary Medical Research [IJCMR] 6, no. 8 (2019). http://dx.doi.org/10.21276/ijcmr.2019.6.8.21.

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26

"American Academy of Dermatology invitational symposium on comedogenicity." Journal of the American Academy of Dermatology 20, no. 2 (1989): 272–77. http://dx.doi.org/10.1016/s0190-9622(89)80058-1.

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27

"1 Final Report on the Safety Assessment of Stearyl Alcohol, Oleyl Alcohol, and Octyl Dodecanol." Journal of the American College of Toxicology 4, no. 5 (1985): 1–29. http://dx.doi.org/10.3109/10915818509078685.

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Stearyl Alcohol, Oleyl Alcohol, and Octyl Dodecanol are long-chain saturated or unsaturated (Oleyl) fatty alcohols. They are used in numerous cosmetic product categories at concentrations of less than 0.1 percent to greater than 50 percent. The metabolism of Stearyl Alcohol and Oleyl Alcohol in rats is described. The results of acute oral toxicity studies indicate a very low order of toxicity. In rabbit irritation tests, these alcohols produced minimal ocular irritation and minimal to mild cutaneous irritation. Stearyl Alcohol produced no evidence of contact sensitization or comedogenicity. Cl
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28

Lee, Eunyoung, and Nahee Kim. "Isopropyl Myristate and Cocoa Butter are not Appropriate Positive Controls for Comedogenicity Assay in Asian Subjects." Journal of Cosmetology & Trichology 01, no. 01 (2015). http://dx.doi.org/10.4172/2471-9323.1000102.

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29

"4 Final Report on the Safety Assessment of Butyl Stearate, Cetyl Stearate, Isobutyl Stearate, Isocetyl Stearate, Isopropyl Stearate, Myristyl Stearate, and Octyl Stearate." Journal of the American College of Toxicology 4, no. 5 (1985): 107–46. http://dx.doi.org/10.3109/10915818509078688.

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The 7 Stearates described in this report are either oily liquids or waxy solids that are primarily used in cosmetics as skin emollients at concentrations up to 25 percent. The toxicology of the Stearates has been assessed in a number of animal studies. They have low acute oral toxicity and are essentially nonirritating to the rabbit eye when tested at and above use concentration. At cosmetic use concentrations the Stearates are, at most, minimally irritating to rabbit skin. In clinical studies the Stearates and cosmetic products containing them were at most minimally to mildly irritating to th
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30

"6 Final Report on the Safety Assessment of Safflower Oil." Journal of the American College of Toxicology 4, no. 5 (1985): 171–97. http://dx.doi.org/10.3109/10915818509078690.

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Safflower Oil is a polyunsaturated edible seed oil consisting primarily of triglycerides of linoleic acid. The oil is used in cosmetics as an emollient in topical lotions and creams at concentrations normally between 0.1 and 5 percent. The pure oil produced slight to moderate comedogenicity. However, products containing up to 5 percent Safflower Oil were not comedogenic in rabbits. Results of animal tests indicated that Safflower Oil was not an eye or skin irritant or contact sensitizer. The oil increased the incidence of 12-dimethylbenz(a)anthracene in rats. Safflower Oil has been used to tre
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31

"Final Report on the Safety Assessment of Corylus Avellana (Hazel) Seed Oil, Corylus Americana (Hazel) Seed Oil, Corylus Avellana (Hazel) Seed Extract, Corylus Americana (Hazel) Seed Extract, Corylus Rostrata (Hazel) Seed Extract, Corylus Avellana (Hazel) Leaf Extract, Corylus Americana (Hazel) Leaf Extract, and Corylus Rostrata (Hazel) Leaf Extract." International Journal of Toxicology 20, no. 1_suppl (2001): 15–20. http://dx.doi.org/10.1080/109158101750300928.

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These ingredients are all derived from hazelnut trees. The two seed oils are expressed from the nuts of the hazelnut tree of the particular species identified. Most current reported cosmetic uses are of the seed oils. The seed extracts are the extract of the nuts of the identified species tree. There is one current report of use of seed extract in cosmetics. The leaf extracts are the extract from the leaves of the particular species tree. There are no current reports of use of these extracts in cosmetics. Analysis of seed oil from one species identified Oleic Acid, Palmitoleic Acid, Linoleic A
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32

"Amended Final Report of the Safety Assessment of Dibutyl Adipate as Used in Cosmetics1." International Journal of Toxicology 25, no. 1_suppl (2006): 129–34. http://dx.doi.org/10.1080/10915810600716679.

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Dibutyl Adipate, the diester of butyl alcohol and adipic acid, functions as a plasticizer, skin-conditioning agent, and solvent in cosmetic formulations. It is reportedly used at a concentration of 5% in nail polish and 8% in suntan gels, creams, and liquids. Dibutyl Adipate is soluble in organic solvents, but practically insoluble in water. Dibutyl Adipate does not absorb radiation in the ultraviolet (UV) region of the spectrum. Dibutyl Adipate is not toxic in acute oral or dermal animal toxicity tests. In a subchronic dermal toxicity study, 1.0 ml/kg day−1 caused a significant reduction in b
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33

"Final Report on the Safety Assessment of Stearyl Heptanoate." Journal of the American College of Toxicology 14, no. 6 (1995): 498–510. http://dx.doi.org/10.3109/10915819509010309.

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The ester Stearyl Heptanoate, a waxy solid that is insoluble in water, is used as a skin conditioning agent-occlusive in a wide variety of cosmetic formulations at varying concentrations (e.g., up to 25% in lip balms, up to 5% in ointments). Studies report a high oral LD50, ≥ 5 g/kg, for rats. Animal data indicate potential for mild skin irritation, but none for sensitization. Undiluted Stearyl Heptanoate did produce some ocular irritation in rabbits, but a 1.5% solution produced no effects. Mutagenesis assays (Ames and micronucleus test) were negative. Clinical data showed no evidence of irri
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34

"An advance in comprehensive “real world” assessment of both the comedogenicity and acnegenicity of sunscreens in acne-prone consumers." Journal of the American Academy of Dermatology 68, no. 4 (2013): AB13. http://dx.doi.org/10.1016/j.jaad.2012.12.058.

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35

Grygierczyk, Kaja, Marta Palacz-Wróbel, and Anna Krzeszewska-Zaręba. "Porównanie skuteczności nawilżenia skóry po zastosowaniu kremów na bazie oleju z wiesiołka i na bazie oleju arganowego." Medycyna Rodzinna 22, no. 3 (2019). http://dx.doi.org/10.25121/mr.2019.22.3.115.

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Introduction. Plant oils are valued ingredients of the oil phase of cosmetics. Argan oil is a semi-drying oil and is composed mainly of unsaturated fatty acids. It also contains saturated fatty acids and antioxidants such as tocopherols and polyphenols, among others. Evening primrose oil is rich in UFA and GLA. It is also a source of vitamins, zinc, calcium, magnesium and selenium. Skin has a protective role in the human body. The quality of its function depends on the level of hydration, among other aspects. Appropriate hydration is achieved with suitable skin care products, including natural
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36

"Final Report on the Safety Assessment of Pentasodium Pentetate and Pentetic Acid as Used in Cosmetics." International Journal of Toxicology 27, no. 2_suppl (2008): 71–92. http://dx.doi.org/10.1080/10915810802244546.

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Pentasodium Pentetate and Pentetic Acid function as chelating agents in cosmetics. Pentasodium Pentetate is readily soluble in water, but the corresponding free acid is not. Pentasodium Pentetate is used in almost 400 cosmetic products over a wide range of product categories, although it is mostly used in hair dyes and colors at use concentrations of 0.1% to 1.0%. Pentetic Acid is used in 150 cosmetic products, mostly in hair dyes and colors. Chelating agents are used in cosmetics to remove calcium and magnesium cations, which impede foaming and cleansing performance and which can cause a haze
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