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1

M.S., Kuznetsova, and Vakulenko T.B. "Features of the pubescence of Calluna vulgaris (L.) Hull plants and its cultivars." Plant Introduction 76 (December 1, 2017): 50–55. https://doi.org/10.5281/zenodo.2331054.

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<strong>Objective</strong> &ndash; to study the trichomes of the stem and leaves of the common heather (<em>C. vulgaris</em> (L.) Hull) and its cultivars belonging to different cultivars groups. <strong>Material and methods.</strong> Annual shoots of heather and its cultivars were examined under light microscopes Stemi-2000-C and MBS-3, increasing by 40, 50 and 100 times. <strong>Results. </strong>There are two types of trichomes on the leaves of the heather of ordinary and investigated cultivars &ndash; simple and glandular. Simple trichomes are most often located on the stem and along the edge of the leaf blade and groove, which opens the stomata. <strong>Conclusions.</strong> Length, density of location on the surface of the leaf and stem and the direction of growth of trichomes in heather and its cultivars differ. Simple trichomes on the stem are located more densely than on the leaf. The longest trichomes of the leaf and stem are on plants of the cultivar &#39;H.E. Beale&#39;, the shortest &ndash; on plants of the cultivar &#39;Golden Carpet&#39;. Simple trichomes are located the most densely on the cultivar &#39;Silver Knight&#39;. The trichomes of the leaf are directed acroscopically on the heather and its cultivars, the trichomes of the stem are chaotic on 6 cultivars. They are directed basically on the common heather and on cultivar &#39;Mullion&#39;, acroscopically &mdash; on two cultivars and almost horizontally &mdash; on the &#39;Golden Carpet&#39;.
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2

N.M., Smilyanets, and Kuznetsova M.S. "The history of introduction of the genus Calluna Salisb. in M.M. Gryshko National Botanical Garden of the NAS of Ukraine." Plant Introduction 72 (December 1, 2016): 22–27. https://doi.org/10.5281/zenodo.2457269.

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The article contains results of research of the archival documents of M.M. Gryshko National Botanical Garden (NBG) of the NAS of Ukraine, relating to the introduction of common heather (<em>Calluna vulgaris </em>(L.) Hull), since 1938. It was found that in the NBG for the first time heather plants were obtained in 1946 from Germany, but in the subsequent inventory documents they are not mentioned. Further, data on the presence of heather in the collections are fixed periodically in inventory registers, the last reference dates back to 1974. After 1979 inventory data were not submitted to the archive, that is why we were not able to trace the presence of common heather in them. Targeted collection of heather varieties began in 2006, &quot;Heather garden&quot; was opened in 2012, where common heather is growing. Also here is the largest in Ukraine collection of varieties of common heather (54 varieties). In &quot;Heather garden&quot; the other plants of the such families as <em>Ericaceae </em>Juss, <em>Magnoliaceae </em>Juss. and <em>Pinaceae </em>Spreng. ex F. Rudolphi are growing. The history of the introduction of heather <em>C. vulgaris</em> in the NBG can be divided into four phases, the last of which (from 2006) is the most productive.
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3

Eva V., Razhina, Smirnova Ekaterina S., Sharaviev Pavel V., Neverova Olga P., and Galushina Polina S. "DEVELOPMENT OF A RECIPE FOR THE PRODUCTION OF BREAD USING AN INFUSION OF COMMON HEATHER AND PUMPKIN PUREE." Vestnik of the Bashkir State Agrarian University 72, no. 4 (2024): 164–68. https://doi.org/10.31563/1684-7628-2024-72-4-164-168.

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Currently, the use of vegetable components in the production of bread is an urgent direction. The purpose of the work was to make a recipe and carry out high-quality bread with the introduction of pumpkin puree and infusion of common heather. The research was carried out in the laboratories of the Faculty of Biotechnology and Food Engineering of the Federal State Budgetary Educational Institution of Higher Education "Ural State Agrarian University". The infusion of common heather was obtained by adding 10 g of dry stems and inflorescences to 200 ml of boiling water. The infusion was used in the manufacture of samples No. 3 and No. 4. Bread production consisted of the following stages: preparation of ingredients, dough kneading, fermentation, kneading, forming, proofing, baking and cooling. The quality control of bread samples was carried out according to organoleptic and physico-chemical characteristics. The results of the organoleptic analysis allow us to identify the best of the enriched samples – No. 4, produced with the introduction of 80 g of pumpkin puree and 70 g of common heather infusion into the recipe. It had a pleasant, slightly spicy taste, a dark yellow color, and a smell peculiar to wheat bread. The results of determining the physico-chemical parameters of bread samples indicated a decrease in acidity as the volume of infusion increased and the moisture content of the crumb increased. The additives did not have a special effect on the porosity of the crumb. Based on the results of the conducted research, we recommend making 80 g of pumpkin puree and 70 ml of common heather infusion in the production of wheat bread.
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Pakhomova, A. I. "Collection of representatives of the Ericaceae family in the botanical garden of the Kuzbass Humanitarian Pedagogical Institute." Проблемы ботаники Южной Сибири и Монголии 22, no. 2 (2023): 251–55. http://dx.doi.org/10.14258/pbssm.2023136.

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Representatives of the heather family are distributed in the temperate climate zone almost throughout the globe and are of great economic importance. The collection of representatives of the Ericaceae family in the Botanical Garden of the Kuzbass Humanitarian Pedagogical Institute of the Federal State Budgetary Educational Institution of Higher Education “Kemerovo State University” consists of 12 species and 28 varieties belonging to 7 genera. Representatives of the genus Rhododendron are represented by 10 species and 7 hybrid varieties. These are predominantly evergreen, semi-deciduous or deciduous shrubs. The collection also includes 11 varieties of common heather with a wide range of flower and leaf colors. Also, in the conditions of the Botanical Garden of KSPI, the varieties Erica carnea L. (ruddy or herbaceous Erica) performed well. Among other representatives of the Heather family, the collection includes 3 species of Kalmia, 2 varieties of Empetrum nigrum L., 2 varieties of Andromeda polifolia L. and Vaccinium myrtillus L. (common blueberry). The experience of relatively successful cultivation of representatives of the heather family allows us to hope for expanding the taxonomic and quantitative composition of the collection, which is actively used for scientific and educational purposes.
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5

Escuredo, Olga, Flores Shantal Rodríguez, Rodriguez Ana Seijo, and M. Carmen Seijo. "Characterization of the honey produced in heather communities (NW Spain)." Journal of Apicultural Research 58, no. 1 (2024): 84–91. https://doi.org/10.1080/00218839.2018.1495417.

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The heathers communities constitute a very interesting habitat for the conservation of the biodiversity and even forhoney production. This honey is very appreciated for its sensory qualities and for coming from a natural barely intervened habitat. This article provides information about the characteristics of 40 honey samples obtained in two subtypesof European dry heaths of the NW of the Iberian Peninsula (Mediterranean and Atlantic heaths). Melissopalynologicaland physicochemical parameters including moisture, pH, hydroxymethylfurfural, diastase activity, color, phenols and flavonoids content, antioxidant activity, mineral (K, Ca, Fe, Mg, Na, P, Zn, and Cu), and sugar (fructose, glucose, sucrose,melezitose, trehalose, and maltose) composition were studied. The samples had a common fingerprint as their Erica pollen content, high electrical conductivity, high mineral content, high phenol content, and the amber to dark amber color,but some significant differences were found between samples produced in Mediterranean dry heaths in relation to thoseproduced in Atlantic heaths
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6

Bernstein, Justin M., Harold K. Voris, Bryan L. Stuart, et al. "Undescribed Diversity in a Widespread, Common Group of Asian Mud Snakes (Serpentes: Homalopsidae: Hypsiscopus)." Ichthyology & Herpetology 110, no. 3 (2022): 560–74. https://doi.org/10.1643/h2022015.

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Bernstein, Justin M., Voris, Harold K., Stuart, Bryan L., Phimmachak, Somphouthone, Seateun, Sengvilay, Sivongxay, Niane, Neang, Thy, Karns, Daryl R., Andrews, Heather L., Osterhage, Jennifer, Phipps, Elizabeth A., Ruane, Sara (2022): Undescribed Diversity in a Widespread, Common Group of Asian Mud Snakes (Serpentes: Homalopsidae: Hypsiscopus). Ichthyology &amp; Herpetology 110 (3): 560-574, DOI: 10.1643/h2022015, URL: http://dx.doi.org/10.1643/h2022015
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7

Kochubey, Alena, Olga Cherepanova, and Irina Petrova. "Daily and season transpiration intensive of Calluna vulgaris (L.) Hill in the trans-Ural south area." Forestry Engineering Journal 13, no. 4 (2024): 209–22. http://dx.doi.org/10.34220/issn.2222-7962/2023.4/13.

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The Trans-Ural region is the southern point of the common heather (C. vulgaris) range. Field ecophysiological&#x0D; study of C. vulgaris plants transpiration intensity (IT) was carried out in connection with the problem of marginal populations adaptation to arid climate. The research was carried out in the forest-steppe of the Trans-Ural region (Kurgan&#x0D; region), where an abundant population of heather grows. The dailyvariation of IT was studied taking into account a set&#x0D; of recorded ecoclimate limiting factors (wind speed, illumination, dynamics of air temperature and humidity, soil temperature) during one growing season (from April to September 2016) under the canopy of a pine forest and in the adjacent&#x0D; clearing. To study IT, annual apical shoots of plants 4 cm long were used in triplicate for each time period. The total&#x0D; sample size on one day of measurements ranged from 30-35 shoots. The transpiration rate was determined by the rapid&#x0D; weighing method, which takes into account the water lost by the shoot over a certain time period. When processing the&#x0D; data, we used correlation analysis (Pearson's correlation coefficient r), which made it possible to clarify the strength and&#x0D; direction of two continuous (metric) variables interaction. Differences in IT daily changes were revealed in plants growing&#x0D; under the forest canopy and in the open areas. Under conditions of long-term atmospheric and soil drought, which is&#x0D; common for the region, in 2016 a sharp decrease in heather water content was observed, starting from 10 a.m. throughout&#x0D; the entire growing season, with the exception of April, when the moisture deficit in the soil and heather tissues was still&#x0D; minimal. In May, maximum IT values in the clearing were noted at 14:00 (8.5 mg/h×10 –4) whereas under the canopy of&#x0D; the tree stand, peak IT values begin at 10 a.m. (12.7 mg/h×10 –4). Daytime summer transpiration in common heather (C.&#x0D; vulgaris) is even less intense than spring transpiration ((3–5 mg/h×10–4).It was revealed that meteorological factors play&#x0D; a decisive role in IT in various types of forest. In open felled areas, the determining factor is PAR (0.81, p &lt; 0.05) and, to&#x0D; a lesser extent, atmospheric temperature (0.69, p &lt; 0.05), and under the canopy - only PAR (0.96, p &lt;0.05). A decrease&#x0D; in IT and, accordingly, photosynthesis leads to a decrease in the population’s vitality and non-ripening of seeds, which is&#x0D; an ecophysiological factor of the heather absence south of Kurgan city.
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Rosnes, Magne, Ellen Synnøve Skilbred, Edvard Aamodt, Ivar Ståle Ertesvåg, and Ragni Fjellgaard Mikalsen. "Study of fire characteristics of forest vegetation in the Atlantic coastal region of Norway." Journal of Physics: Conference Series 2885, no. 1 (2024): 012066. http://dx.doi.org/10.1088/1742-6596/2885/1/012066.

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Abstract Understanding of wildfire risk requires an understanding of the natural species’ fire dynamics. This study investigates fire characteristics of common wildland species in Norwegian forests – stair-step moss, lingonberry shrub, juniper, bilberry, and heather. Cone calorimetry experiments were conducted after conditioning samples to similar moisture content. Stair-step moss and bilberry stems exhibited longer burning times and lower peak heat release rates, suggesting a slower, more sustained combustion. Heather, despite age differences, showed similar fire behaviours, indicating moisture content’s role in wildfire risk. Evergreens displayed the most intense fire development, with juniper potentially acting as a ladder species for vertical fire spread.
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9

Karpiński, Tomasz M., Joanna Karpińska, and Marcin Ożarowski. "Polish honeys exhibit activity against Pseudomonas aeruginosa isolated from wounds." Leczenie Ran 21, no. 1 (2024): 3–7. http://dx.doi.org/10.60075/lr.v21i1.60.

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Pseudomonas aeruginosa is recognized as an opportunistic pathogen and a common contributor to wound infections. This study focused on evaluating the antibacterial activity of selected Polish honeys against P. aeruginosa. Six bacterial strains isolated from wounds and four types of honeys (multifloral, linden, buckwheat, and heather) were utilized. The minimal inhibitory concentrations (MIC) were determined through the micro-dilution method employing 96-well plates, while antibiofilm activity was assessed using fluorescence microscopy after a 4-hour incubation period with the honeys. Results indicated diverse antibacterial efficacy among honeys, with linden and heather honeys demonstrating the most potent activity. Linden honey displayed an average MIC of 20.8%, while heather honey exhibited an MIC of 25%. Both honeys significantly reduced biofilm formation, with linden honey achieving a reduction of 54-67% and heather honey of 45-58%. Buckwheat and multifloral honeys exhibited lower activity, demonstrating average MIC levels of 37.5% and 41.7%, respectively, and a biofilm reduction below 20%. Conclusively, Polish honeys exhibited promising activity against both planktonic and biofilm forms of P. aeruginosa. These findings suggest potential applications in wound healing treatments, emphasizing the need for further research in this area. The study contributes valuable insights to the limited literature on the antibacterial activity of Polish honeys.
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10

Schellenberg, Jenny, and Erwin Bergmeier. "The Calluna life cycle concept revisited: implications for heathland management." Biodiversity and Conservation 31, no. 1 (2021): 119–41. http://dx.doi.org/10.1007/s10531-021-02325-1.

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AbstractHeather, Calluna vulgaris, is a key species of European dry heath and central determinant of its conservation status. The established Calluna life cycle concept describes four phases—pioneer, building, mature, and degeneration—distinguishable by growth and vitality characteristics of undisturbed plants grown from seeds. However, little is known about the life cycle and ageing of plants subjected to severe disturbance, although measures to this effect (burning, mowing) are common in heathland management. We studied the vitality of over 400 heather plants by examining multiple morphological (plant height, long shoot and inflorescence lengths, flowering activity), anatomical (growth rings) and environmental (management, nitrogen deposition, climate) attributes. We found Calluna vitality to be mainly determined by the aboveground stem age, and that severe disturbances promote vigorous vegetative regeneration. Ageing-related shifts in the habit and vitality of plants resprouting from stem-base buds is similar to that of seed-based plants, but the former revealed higher vitality when young, at the cost of a shorter life span. In contrast, plants originating from decumbent stems resemble building-stage plants but apparently lack the capacity to re-enter a cycle including stages other than degeneration-type. As a consequence, we supplemented the established heather life cycle concept with a post-disturbance regeneration cycle of plants derived from resprouting. We conclude that management of dry lowland heathlands should include rotational small-scale severe disturbance to support both seed germination and seedling establishment as well as vegetative regeneration chiefly of young heather plants capable of resprouting from buds near rootstock.
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11

Cherepanova, Olga, Irina Petrova, Stanislav Sannikov, and Yulia Mishchihina. "Diagnostics and Description of a New Subspecies of Calluna vulgaris (L.) Hull from Western Siberia." Horticulturae 9, no. 3 (2023): 386. http://dx.doi.org/10.3390/horticulturae9030386.

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The article presents the results of the study of fifty populations of common heather (Calluna vulgaris (L.) Hull) collected throughout its range. A phased comparative analysis (genetic, biochemical, anatomical, morphological, and ecological) was carried out with the estimation of indicators that included two key populations—Zavodouspenskoe (Pritobolye, Western Siberia) and Luga (Baltic, Eastern Europe). It was concluded that heather growing in Western Siberia should be identified as a separate taxonomic group, giving it the status of a subspecies. The gene pool of Pritobolye populations (including Zavodouspenskoe) is represented by the completely dominant (100%) monohaplotype S, which is not found anywhere else. The heather plant growing in Zavodouspenskoe has a longer lifespan. It is distinguished by larger linear leaf dimensions (length 2.06 ± 0.09 mm), thicker cuticle (4.77 ± 0.33 μm), increased number of trichomes (18.98 ± 0.56), and a reduced number of stomata (13.60 ± 0.63) than that growing in Luga. The new subspecies differs in biochemical composition: twice less content of epicatechin (average 1.992 ± 0.005 mg g−1), three times more myricetin (average 2.975 ± 0.005 mg g−1), twice as much chlorogenic acid (average 2.763 ± 0.004 mg g−1). An ecological feature is that C. vulgaris does not grow in the swamps of Western Siberia and has a small population. This species has a high horticultural potential and requires protection as its population in Western Siberia continues to decline rapidly.
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Russell, Heather. "Supporting Infant Feeding In Vegan Familes." Student Midwife 5, no. 3 (2022): 6–9. http://dx.doi.org/10.55975/qtjj9547.

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Veganism is a philosophical belief protected by law and a growing social movement. Paediatric dietitians can provide expert advice to address any dietary concerns encountered on infant-feeding journeys. However, student and qualified midwives, and other healthcare professionals are in an optimal position to support person-centred care for families who make lifestyle choices in line with their beliefs and values. In this article, Heather explores the impact of veganism on infant feeding and addresses common questions.
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Thompson, Francis. "From Prestige Project to Simply Shell: The Short History of the Northern Arts and Cultural Centre." Canadian Theatre Review 73 (December 1992): 45–50. http://dx.doi.org/10.3138/ctr.73.015.

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The Northern Arts and Cultural Centre, once a monument to pan-Canadian generosity and Yellowknife civic pride, is now living off the proceeds of bingos. “I don’t want to see it go ... I’ll chain myself to the door if I have to do it,” says Heather Ross, a long-time NACC board member, director and actress. And more recently, bingo organizer. Ross’ despondency and determination may be common in Canada’s theatrical community. But NACC’s riches-to-rags story is anything but common. This is not some vulnerable old institution, slipping slowly into financial oblivion. This 313-seat theatre opened in 1984 after unprecedented community mobilization raised $1.3 million in four years.
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Šukele, Renāte, Ingus Skadiņš, Rudīte Koka, and Dace Bandere. "Antibacterial effects of oak bark (Quercus robur) and heather herb (Calluna vulgaris L.) extracts against the causative bacteria of bovine mastitis." Veterinary world 15, no. 9 (2022): 2315–22. https://doi.org/10.14202/vetworld.2022.2315-2322.

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Background and Aim:&nbsp;Bovine mastitis has a negative impact on animals, and improper antibiotic use has caused an increase in bacterial resistance. Therefore, medicinal plants could serve as an alternative treatment for this condition. Polyphenols have potential as antibiotic agents. Oak bark has long been used as a medicine and has shown antibacterial effects. Moreover, research on heather plant demonstrated that it has antibacterial properties. This study aimed to assess the antibacterial effects of oak (Quercus robur) bark and heather (Calluna vulgaris L.) herb extracts against common bovine mastitis pathogens. Materials and Methods:&nbsp;Dried oak bark and heather herb were used to prepare extracts using 30%, 50%, and 70% ethanol and acetone as solvents. Their polyphenol content was determined using the Folin&ndash;Ciocalteu method. Bovine mastitis- inducing clinical isolates of&nbsp;Escherichia coli,&nbsp;Streptococcus agalactiae,&nbsp;Streptococcus uberis,&nbsp;Serratia liquefaciens,&nbsp;Staphylococcus aureus, and reference cultures of&nbsp;S. aureus&nbsp;and&nbsp;E. coli&nbsp;were used for antibacterial tests. All extracts were screened through a disk diffusion test to ascertain their antibacterial effects, and the minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined for the most effective extracts. Results:&nbsp;Oak bark extracts had variable antibacterial effects against&nbsp;S. aureus&nbsp;and&nbsp;Streptococcus&nbsp;strains, but no statistically significant difference was observed in activity against&nbsp;E. coli. The disk diffusion test showed that the oak bark extracts obtained using acetone and ethanol at 30% yielded the best results. However, the 70% acetone oak extract alone affected all types of bacteria. Further antibacterial tests of 70% acetone and 30% ethanol oak extracts revealed that the lowest MIC and MBC scores were against&nbsp;S. aureus&nbsp;strains and&nbsp;E. coli&nbsp;reference cultures. Conversely, the heather herb extracts exhibited broader activity against all types of bacteria, although better results were observed against Gram-positive bacteria. There was also a negative correlation between solvent concentration and antibacterial effect (p &lt; 0.05, r = &minus;0.507). The highest inhibition zone scores and broadest spectrum were observed in samples prepared in 30% ethanol. There was no statistically significant correlation between the phenolic content of plants and their antibacterial effects. Conclusion:&nbsp;Oak bark and heather extracts could be used as potential antibacterial agents against bovine mastitis pathogens.
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Kerslake, J. E., and S. E. Hartley. "Phenology of Winter Moth Feeding on Common Heather: Effects of Source Population and Experimental Manipulation of Hatch Dates." Journal of Animal Ecology 66, no. 3 (1997): 375. http://dx.doi.org/10.2307/5983.

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16

Chen, Yan, Regina Bracy, and Roger Rosendale. "(61) Nutrient Management of Common Herbaceous Perennial Plantings in Southern Landscapes." HortScience 41, no. 4 (2006): 1071B—1071. http://dx.doi.org/10.21273/hortsci.41.4.1071b.

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While herbaceous perennials continuously gain popularity in southern landscape plantings, the nutrient requirements of many species in this group are still unknown. The business goal of lawn and garden care companies emphasizes aesthetic value of the urban landscape. Improper nutrient management, such as the overapplication of fertilizers, is inefficient and may result in increased pest problems and risks of contaminating ground and surface waters by nutrient runoff. Seven herbaceous perennials (lantana, rudbeckia, purple cone flower, daylily, mexican heather, cigar plant, and guara) were planted in simulated landscape beds. Fertilizers applied included one or two OsmocotePlus 16-8-12 tablets (7.5 g), OsmocotePlus 15-9-12 (5 months) at 0, 33, 66, and 131 g/m2 at planting, or applying OsmocotePlus 15-9-12 (5 months) 33 g/m2 or one OsmocotePlus tablet at the time of planting plus another 33 g/m2 topdressing after flowering. Plant growth of rudbeckis, purple cone flower, and lantana were highest at 131 g/m2 applied at planting, but resulted in similar overall plant quality as with 33 or 66 g/m2 treatments. Daylily growth was similar across fertilization treatments, and overall quality decreased at high fertilization rates with more severe daylily rust observed on these plants. Applying one OsmocotePlus 7.5-g tablet resulted in similar plant quality with applying OsmocotePlus 33 and 66 g/m2, but significantly reduced the amount of fertilizer used. Additional topdressing after flowering did not further increase plant quality in fall, but may affect the overwintering survival of perennial plants.
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Bast, Joseph L. "Comment on Brent Beal's and Heather Olson Beal's “Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League”." Journal of School Choice 7, no. 4 (2013): 508–14. http://dx.doi.org/10.1080/15582159.2013.839917.

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Houck, Eric A. "Comment on Brent Beal's and Heather Olson Beal's “Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League”." Journal of School Choice 7, no. 4 (2013): 517–19. http://dx.doi.org/10.1080/15582159.2013.839920.

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Hagstrup, Marie, Dan Bruhn, Kent Olsen, Mie Lukassen, and Cino Pertoldi. "Molecular study of dietary diversity of the Exmoor-ponies (Equus feruscaballus)." GABJ 4, no. 1 (2021): 53–70. http://dx.doi.org/10.46325/gabj.v4i1.111.

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Much is still to learn about the reintroducing of horses in rewilding in regards to their forage on woody species as horses are often categorized as true grazers and dwellers of the open habitat. Relative amount of woody vegetation and different woody species ingested by Exmoor-ponies (Equus feruscaballus) in the Rewilding Mols project area in the Mols BjergeNational Park, Denmark, during winter were determined using macroscopic analysis of faeces and DNA metabarcoding. This showed an increase in the relative amount of woody vegetation ingested during winter (December – February) peaking at 35.2% in January. The three most dominating woody species were common heather (Calluna vulgaris), common oak (Quercus robur), and scots pine (Pinus Sylvestris) with a total relative abundance in the diet throughout the entire study period of ‘10’%, ‘10’% and ‘6’%, respectively. No direct debarking by the Exmoor-ponies was observed nor evidence of debarking on trees in the area (data not shown).The current forage on woody vegetation during winter was concluded not to be significant in order to trigger canopy dieback and eventually cause retrogressive succession.If the goal for a specific rewilding project includes creation of clearings in forest stands one should reconsider the choice of Exmoor-ponies.
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Starchenko, Galyna, Andriy Hrytsyk, Ain Raal, and Oleh Koshovyi. "Phytochemical Profile and Pharmacological Activities of Water and Hydroethanolic Dry Extracts of Calluna vulgaris (L.) Hull. Herb." Plants 9, no. 6 (2020): 751. http://dx.doi.org/10.3390/plants9060751.

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According to the WHO data (2017), depression is the most predominant disease worldwide, with about 300 million people suffering from it, and bipolar disorder is the second most common. Therefore, it is relevant to research new medicines based on medicinal herbal raw materials with anti-anxiety and antidepressant effects. Common heather (Calluna vulgaris (L.) Hull.), a flowering plant of the Ericaceae family, is a promising species for research in this area. The aim of this study was to investigate the phytochemical profile and several biological activities of hydroethanolic dry extracts from the C. vulgaris herb. Nineteen phenolic substances were identified and quantified in the extracts by HPLC. The quantitative content of the basic groups of biologically active compounds was determined by spectrophotometry. Arbutin was dominant among the hydroquinone derivatives; chlorogenic acid among the hydroxycinnamic acids; rutin, hyperoside and quercetin-3-D-glucoside among the flavonoids; and (+)-gallocatechin and (-)-epigallocatechin among the tannin metabolites. The water and hydroethanolic extract were compared, the extract of C. vulgaris herb obtained with 70% hydroethanolic had the most pronounced anti-inflammatory, antimicrobial, anxiolytic, stress-protective, anti-anxiety and anti-depressant effects, and it is a promising substance for the development of new drugs or food supplements.
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Bunce, Robert G. H., Claire M. Wood, and Simon M. Smart. "The Ecology of British Upland Landscapes. I. Composition of Landscapes, Habitats, Vegetation and Species." Journal of Landscape Ecology 11, no. 3 (2018): 120–39. http://dx.doi.org/10.2478/jlecol-2018-0015.

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Abstract A primary requirement for policy objectives is reliable figures on the composition of any region. Currently there is no comprehensive, definitive set of statistics for the British Uplands, hence the present paper. An overview of the background to the region is first provided, together with some examples of the available figures and a discussion of their limitations. The paper uses a formal structure, with landscapes at the highest level followed by habitats, then vegetation, and finally species, with exact definitions of the categories applied at all levels. The figures are produced from a survey of stratified, random one kilometre squares. The tables give comprehensive figures for Great Britain (GB) as a whole, and also England, Wales and Scotland. The Uplands are shown to cover 38 % of the country. In terms of UK Broad Habitats, Bog is the most common overall (2062 k ha). It is estimated that 41 % of upland vegetation in Britain is grazed by sheep, and Cervus elephus (red deer) are particularly evident in Scotland. Walls (mainly drystone) are the most important linear feature (84 k km) but hedgerows (30 k km) are also widespread. The major vegetation classes are those linked to moorlands and bogs (about 25 %) but those associated with fertile soils are also common (10 %). In terms of species, Potentilla erecta (tormentil) is the most frequent species with four other acid grassland species in the top ten. Calluna vulgaris (ling heather) has the highest cover in Great Britain (14.8 %).
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El Fattah, Fatima Ezzahraa. "The Orthodox Dichotomy between the Secular and Islamic Feminisms in Moroccan Young Activists." Journal of Gender, Culture and Society 1, no. 1 (2021): 14–21. http://dx.doi.org/10.32996/jgcs.2021.1.1.3.

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There has been an ongoing interest in youth activism in recent decades, especially in western countries where youth organizations and associations are very common in schools and colleges. Heather Lewis-Charp et al. confirm that although there is an increasing interest in youth political engagement, there are very few empirical studies on the subject matter (Shawn Ginwright 2006, 22). This lack of research applies to the issue of youth activism and political engagement not just in Morocco, but across the Middle East and North Africa (MENA). In the wake of the so-called Arab spring, the focus on youth political engagement and activism grew, given the important role of youth and other marginalized communities – especially women – in protests around the region. In Morocco, a large number of the protesters in the February 20th movement were young people; of these, many were actively associated with feminist organizations and work. This is in contrast to the continued association between feminist activism in Morocco and older generations. This chapter will start by sketching a history of feminist movements and organizations in Morocco and will follow with a discussion of recent activist work by two prominent activists, Zineb Fasiki and Youssef Gherradi.
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Elliott, Alan C., Stoffel P. Bester, Ronell R. Klopper, E. Charles Nelson, and Michael D. Pirie. "Curating an online checklist for Erica L. (Ericaceae): contributing to and supporting global conservation through the World Flora Online." PhytoKeys 243 (June 21, 2024): 121–35. http://dx.doi.org/10.3897/phytokeys.243.121555.

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To support the work of the Global Conservation Consortium for Erica and update the Erica checklist in the World Flora Online (WFO), we have curated the taxonomic backbone in the WFO by expanding it to include updated nomenclatural information from the International Plant Name Index, missing names present in the World Checklist of Vascular Plants (WCVP), the Botanical Database of Southern Africa (BODATSA), and from the “International register of heather names” database, a data source not readily available online. The result is the most robust database of Erica names to date, including 851 species, 111 subspecies, 244 varieties, and 2787 synonyms, which is a reliable reference for initiatives such as the Erica identification aid, conservation prioritisation, and gap analyses. We disambiguate common orthographic variants within the database and present an overview of these. We also comment on the correct orthography of E. heleophila Guthrie &amp; Bolus and E. michellensis Dulfer and the validity of E. tegetiformis E.G.H.Oliv. are discussed, and the use of E. adunca Benth. for a South African species rather than E. triceps Link, which is here regarded as insufficiently known and of uncertain application, is clarified.
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Rehm, Jürgen, Maximilien Rehm, Hannu Alho, et al. "Alcohol dependence treatment in the EU: A literature search and expert consultation about the availability and use of guidelines in all EU countries plus Iceland, Norway, and Switzerland." International Journal of Alcohol and Drug Research 2, no. 2 (2013): 53–67. http://dx.doi.org/10.7895/ijadr.v2i2.89.

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Rehm, J., Rehm, M. X., Alho, H., Allamani, A., Aubin, H., Bühringerm G,m Daeppen, J., Frick, U., Gual, A., &amp; Heather, N. (2013). Alcohol dependence treatment in the EU: A literature search and expert consultation about the availability and use of guidelines in all EU countries plus Iceland, Norway, and Switzerland. International Journal of Alcohol and Drug Research, 2(2), 53-67. doi: 10.7895/ijadr.v2i2.89 (http://dx.doi.org/10.7895/ijadr.v2i2.89)Aim: To describe guidelines and common practices for alcohol dependence treatment in Europe.Design: Systematic and qualitative review; for each country, guidelines were identified via systematic literature research, followed by interviews with treatment experts.Setting: European Union (EU) countries plus Iceland, Norway, and Switzerland.Participants: Experts in alcohol dependence treatments and treatment systems.Measure: Semi-structured questionnaire for interviews.Findings: While fewer than half of EU countries have formal national guidelines for alcohol dependence treatment, a majority of these countries have guidelines by professional organizations such as psychiatric or neuropsychopharmacologic societies, and several are currently developing such guidelines. Abstinence is the usual treatment goal, but the majority of countries accept reduction of drinking as an intermediate or secondary goal, in practice even more than in the guidelines. Psychotherapy, mainly cognitive-behavioral approaches, motivational interviewing, and family therapy, is the most common treatment for relapse prevention, in part accompanied by pharmacotherapy (disulfiram, acamprosate and naltrexone being used most often).Conclusions: There are differences in treatment for alcohol dependence in Europe. The introduction of reduction of drinking as one treatment goal may attract more patients.
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Krzesiński, Paweł, Agata Galas, Grzegorz Gielerak, and Beata Uziębło-Życzkowska. "Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure." Cardiology Research and Practice 2020 (March 21, 2020): 1–9. http://dx.doi.org/10.1155/2020/9371967.

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Anaemia is a common comorbidity in patients with heart failure (HF) and is associated with more severe symptoms and increased mortality. The aim of this study was to evaluate haemodynamic profiles of HF patients with respect to the presence of reduced left ventricular ejection fraction (LVEF) and anaemia. Methods and Results. Haemodynamic status was evaluated in 97 patients with acute decompensated HF. Impedance cardiography, echocardiography, and N-terminal probrain natriuretic peptide (NT-proBNP) results were analysed. The study group was stratified into four subgroups according to LVEF (&lt;40% vs ≥40%) and the presence of anaemia (haemoglobin &lt;13.0 g/dL in men and &lt;12.0 g/dL in women). Thoracic fluid content was higher (p=0.037) in anaemic subjects, while no significant relation between anaemia and NYHA was observed. Anaemic subjects with LVEF ≥ 40% were distinguished from those with LVEF &lt; 40% by significantly higher stroke index (p=0.002), Heather index (p=0.014), and acceleration index (p=0.047). Patients with reduced LVEF and anaemia presented the highest NT-proBNP (p=0.003). Conclusions. In acute decompensated HF, anaemia is related with fluid overload, relatively higher cardiac systolic performance but no clinical benefit in patients with preserved/midrange LVEF, and increased left ventricular tension, fluid overload, and impaired cardiac systolic performance in patients with reduced LVEF.
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Knowles, Mary, Xun Li, Carlos Lehnebach, Philip Lester, and Julia Kasper. "Pollen samples from a bumble bee (Hymenoptera: Apidae) collection show historic foraging on introduced and native plants in the South Island of New Zealand." PLOS ONE 17, no. 12 (2022): e0278860. http://dx.doi.org/10.1371/journal.pone.0278860.

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Historic pollination networks are important to understand interactions between different plant and pollinator species, as well as to differentiate between causes and consequences of present insect population decline. Natural history collections in museums store biological proxy data, which is used to reconstruct historic pollination networks of bumble bees. Four bumble bee species (Bombus terrestris, B. ruderatus, B. hortorum and B. subterraneus) were introduced to Aotearoa New Zealand in 1885 specifically for pollination purposes. Pollen samples were collected from museum specimens of three of the four NZ species of bumble bee (excluding B. subterraneus) collected between 1954 and 1972 from 56 locations across the South Island, New Zealand. The most common plants identified on all three bumble bee species were Calluna vulgaris (heather), Ulex (gorse), Cytisus (broom), and Trifolium repens (white clover). However, all three bumble bee species also carried pollen from several native plants (e.g. Arthropodium, Weinmannia, Plagianthus, Quintinia, Veronica, Melicytus) and potentially had been involved in the pollination of these species. This study adds new plant species known to be foraged upon by bumble bees in Aotearoa New Zealand. Further studies on pollination networks in New Zealand will help us understand any changes in host plant preferences over time and after the time period covered by this study.
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Elliott, Alan C., Stoffel P. Bester, Ronell R. Klopper, E. Charles Nelson, and Michael D. Pirie. "Curating an online checklist for Erica L. (Ericaceae): contributing to and supporting global conservation through the World Flora Online." PhytoKeys 243 (June 21, 2024): 121–35. https://doi.org/10.3897/phytokeys.243.121555.

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To support the work of the Global Conservation Consortium for <i>Erica</i> and update the <i>Erica</i> checklist in the World Flora Online (WFO), we have curated the taxonomic backbone in the WFO by expanding it to include updated nomenclatural information from the International Plant Name Index, missing names present in the World Checklist of Vascular Plants (WCVP), the Botanical Database of Southern Africa (BODATSA), and from the "International register of heather names" database, a data source not readily available online. The result is the most robust database of <i>Erica</i> names to date, including 851 species, 111 subspecies, 244 varieties, and 2787 synonyms, which is a reliable reference for initiatives such as the <i>Erica</i> identification aid, conservation prioritisation, and gap analyses. We disambiguate common orthographic variants within the database and present an overview of these. We also comment on the correct orthography of <i>E. heleophila</i> Guthrie &amp; Bolus and <i>E. michellensis</i> Dulfer and the validity of <i>E. tegetiformis</i> E.G.H.Oliv. are discussed, and the use of <i>E. adunca</i> Benth. for a South African species rather than <i>E. triceps</i> Link, which is here regarded as insufficiently known and of uncertain application, is clarified.
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Zhou, Zhao Xia. "Statistical Analyses on Usage of Water Heater in Urban Residential Buildings." Applied Mechanics and Materials 521 (February 2014): 748–51. http://dx.doi.org/10.4028/www.scientific.net/amm.521.748.

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A survey for water heater in urban residential buildings is carried in Wuhan. The results show that more than 40% subjects use solar energy water heat. More than 20% subjects point out the energy consumption of water heater should be decreased. There are about 24.8% subjects take initial cost as the first place when they chose water heater. 44.2% subjects know about heat pump water heater, but they could not buy it if the initial cost is too high. There are 84% subjects could select heat pump water heater when the cost is no more 20% high than the average price of the common water heaters. Moreover, the energy consumptions of residential water heaters are also investigated. The energy consumption characteristics of water heater in Wuhan are analyzed.
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29

Viteritti, Joseph P. "Men in Tights and the Multiplication of Mixed Metaphors: Comment on Brent Beal's and Heather Olson Beal's “Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League”." Journal of School Choice 7, no. 4 (2013): 505–7. http://dx.doi.org/10.1080/15582159.2013.839915.

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30

Coulson, Andrew. "A Relic of Scholasticism in an Age of Science: Comment on Brent Beal's and Heather Olson Beal's “Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League”." Journal of School Choice 7, no. 4 (2013): 515–16. http://dx.doi.org/10.1080/15582159.2013.839918.

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31

Linhoss, John E., Joseph L. Purswell, and Jeremiah D. Davis. "Evaluating Radiant Heater Performance Using Chick Thermal Preference and Spatial Analysis." Applied Engineering in Agriculture 37, no. 3 (2021): 447–54. http://dx.doi.org/10.13031/aea.14466.

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HighlightsRadiant heaters from different manufacturers with the same power output do not produce the same radiant distribution.Heater net usable area is influenced by heater elevation and chick preferences for radiant flux.Radiant heaters should be operated at manufacturer specified elevations to minimize potential reductions in performance.Abstract. Radiant heaters are the most common method of providing supplemental heat in broiler houses, but little is known about how efficiently they create a suitable thermal environment for brooding chicks. This study investigates the net usable area (NUA), or the total floor area within the range of radiant flux preferred by chicks, for six round radiant heaters with a nominally rated power output of 11.72 kW. NUA was calculated for all heaters at three manufacturer specified heights 1.52, 1.83, and 1.98 m and at a distance 0.3 m below manufacturer specified height (1.22 m). NUA ranged from 11.6 ± 0.7 m2 to 59.4 ± 19.7 m2 and increased with heater mounting elevation. Results indicate that radiant heaters from different manufacturers with the same power output do not produce the same NUA. NUA was also shown to be higher at 8 d than 1 d for all heaters and was attributed to the decrease in chick preference for level of radiant flux during the first week of brooding. NUA gross radiant coefficient (GRC), or the proportion of the heat energy in the fuel that reached the floor and was within the thermal comfort range of the chicks, did not exceed 0.37 for any heater and decreased with heater elevation. Operating a heater below the manufacturer specified mounting elevations led to reduced NUA and an overall less efficient use of fuel. Keywords: Broiler chicks, Brooding, Net usable area, Radiant heaters, Thermal preference.
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32

Hussein, Tareq, Omar Al-Jaghbeer, Nizar Bqour, Bilal Zidan, and Bashar Lahlouh. "Exposure to Aerosols Emitted from Common Heating Combustion Sources Indoors—The Jordanian Case as an Example for Eastern Mediterranean Conditions." Atmosphere 13, no. 6 (2022): 870. http://dx.doi.org/10.3390/atmos13060870.

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In Jordan, ~61% of total residential energy consumption is consumed by heating spaces using portable kerosene (K) and liquified petroleum gas (LPG) heaters. Here, we evaluated the indoor air quality (IAQ) versus the use of K and LPG heaters inside a test room reflecting the typical conditions of Jordanian dwellings during the winter season. The experimental setup included particle size distribution (diameter 0.01–25 µm) measurements, and we utilized a simple sectional indoor aerosol model (SIAM) to estimate the emission rate and lifetime of the combustion products in the test room. The particle number (PN) concentration during the LPG operation was 6 × 104–5.9 × 105 cm−3, depending on the setting at minimum, medium, or maximum. The K heater operation increased with the PN concentrations to a range of 4 × 105–8 × 105 cm−3. On average, the particle losses were 0.7–1.6 h−1 for micron particles (1–10 µm) and 0.8–0.9 h−1 for ultrafine particles (&lt;0.1 µm). The emission rate from the LPG heater was 1.2 × 1010–2.8 × 1010 particles/s (6.6 × 106–8.0 × 106 particles/J), and that for the K heater was about 4.4 × 1010 particles/s (1.9 × 107 particles/J). The results call for the immediate need to apply interventions to improve the IAQ by turning to cleaner heating processes indoors.
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Brantley, Kristen D., Thomas U. Ahearn, Emily Norton, et al. "Abstract 3594: Performance of common general-population breast cancer risk prediction models in 14 cohorts." Cancer Research 85, no. 8_Supplement_1 (2025): 3594. https://doi.org/10.1158/1538-7445.am2025-3594.

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Abstract Background: Several breast cancer (BC) risk prediction models are used in clinical practice to identify women eligible for enhanced screening or prevention strategies. While these models have been independently validated in specific and often separate contexts, their performance has not been systematically evaluated and compared across a wide range of populations or age ranges. Methods: We collected individual-level baseline questionnaire data and incident cancer diagnoses from 14 cohorts participating in the Breast Cancer Risk Prediction Project (BCRPP), representing the United States (N=12), Canada (N=1) and Australia (N=1). After harmonizing data across cohorts, five-year absolute risk estimates for invasive breast cancer were derived using four models: BCRAT, iCARE-Lit, Tyrer-Cuzick (all estimating risk in women aged ≥20-75 years) and the Black Women’s Health Study (BWHS) calculator (estimating risk in Black women aged ≥30-70 years). Using the iCARE-calibrate function in R we estimated the area under the curve (AUC) and 95% confidence intervals (CI) within each cohort, using absolute risk designations to incorporate age. Expected to observed (E/O) absolute risks were estimated on average and within expected absolute risk deciles for each cohort. To align with its intended use in clinical practice, calibration of the BWHS calculator (and comparison to other models) was performed within the subset of Black women pooled from all cohorts. Results: A total of 1, 041, 708 women, enrolled in studies between 1976-2015, were included. Within five years of baseline cohort entry, 116, 113 invasive breast cancer cases were diagnosed. Mean age at baseline ranged from 34 to 62 years. Within cohorts, discrimination was similar across models but varied substantially across cohorts. Age-incorporated AUCs ranged from 0.55-0.77, with most cohort-specific AUCs under 0.65 and higher AUCs observed among younger cohorts. Calibration, measured by E/O ratios, differed substantially by both cohort and risk prediction model. For the majority of cohort-model combinations, risk was overestimated in the upper risk deciles. In general, E/O ratios were more similar for BCRAT and Tyrer-Cuzick models compared to iCARE-Lit, which tended to overestimate risk more on average. In the subset of Black women aged ≥30-70 years (N=84, 594, N=824 invasive cases in 5 years), age-incorporated AUCs ranged from 0.61 to 0.64. While risk was overestimated in the upper risk deciles for all models, overestimation was 13-118% lower for the BWHS calculator. Conclusion: The discrimination and calibration of existing risk prediction models varied across studies. Future model development including additional risk factors (e.g., genetic and mammographic information) should leverage diverse training data and flexible models to ensure risk estimates perform well across different regions, countries, and ethnicities. Citation Format: Kristen D. Brantley, Thomas U. Ahearn, Emily Norton, Julie Palmer, Gary Zirpoli, Matt Barnett, Marian L. Neuhouser, Lauren Teras, James Hodge, Thomas E. Rohan, Roger Milne, A. Heather Eliassen, Hongyan Huang, Yu Chen, Katie M. O'Brien, Cari Kitahara, Garnet Anderson, I-Min Lee, Nilanjan Chatterjee, Montserrat Garcia-Closas, Peter Kraft, Breast Cancer Risk Prediction Project. Performance of common general-population breast cancer risk prediction models in 14 cohorts [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 3594.
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Gelao, Gennaro, Roberto Marani, and Anna Gina Perri. "Self Heating and IR Emission Effects Simulation of Radiative Heater on Power MOS AC Switch." International Journal of Emerging Technology and Advanced Engineering 12, no. 6 (2022): 115–22. http://dx.doi.org/10.46338/ijetae0622_15.

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High power IR heaters are very common but some have high switch on current due to the high difference of the electric resistance at ambient temperature and at steady state temperature. In this paper we develop a thermal model of these IR heaters considering the radiated power which is proportional to the fourth power of the temperature, according to the Stefan Boltzmann law. We propose a new circuit based on a series of two power MOS and simulate the switching, showing the temperature and heat flux inside the heater and MOSFET. Keywords— IR emission effects, Radiate Heater, MOSFET Devices, Modelling, Advanced Design System (ADS).
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VIRAG, Piroska, Ioana C. BRIE, Claudia C. BURZ, et al. "Modulation of the UV-B-induced Oxidative Stress and Apoptosis in HaCaT Cell Line with Calluna vulgaris Extract." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 43, no. 2 (2015): 313–19. http://dx.doi.org/10.15835/nbha43210000.

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The reactive oxygen species (ROS) production due to ultraviolet B (UV-B) exposure is extremely harmful to the skin. It causes lesions of DNA, proteins and lipids and leads to cellular death. In the present study the UV-B-induced ROS and subsequent apoptosis in the human keratinocyte cell line (HaCaT) were counterbalanced by a plant extract with antioxidant capacity. Some molecules modulated by common heather (Calluna vulgaris) (CV) extract through which this may exert its photoprotective effects were also identified. The ROS were evaluated with CM-H2DCFDA assay, while apoptosis and Bax-α/Bcl-xL molecules with ELISA. The extract was standardized according to its polyphenolic content and the most important biologically active compounds, such as hyperozid, quercetin, isoquercetin, kampferol were evidenced by high-performance liquid chromatography. The UV-B induced ROS production occurred at its highest level at 2 h after the exposure of the HaCaT cells, while apoptosis later, at 4 h. The most significant changes in Bax-α and Bcl-XL proteins induced by UV-B, as well as the highest effect of the extract on apoptosis, were both registered at 4 h. The CV extract decreased concentration- and time-dependently the UV-B-induced ROS production and prevented apoptosis. These effects of CV occurred, at least to a certain extent, due to the modulation of Bax-α/Bcl-XL proteins. These findings suggest that skin cells could be protected from some of the UV-B-induced harmful effects by the administration of the CV extract, which may be further exploited as a potential photoprotective agent.
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Mokhova, L. M. "Special aspects of the formation of subfossil pollen assemblages from Ketoi Island (Central Kuril Islands)." Geosystems of Transition Zones 8, no. 2 (2023): 142–52. http://dx.doi.org/10.30730/gtrz.2024.8.2.142-152.

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The composition and ratios of main components of pollen assemblages from the surface layer of peatlands, soils, lake sediments, and alluvial silts in different parts of the Ketoi Island were analyzed. The island, despite its small size, is distinguished by a complex organization of the landscapes. The pollen spectra represent well the local vegetation at the sampling sites, regardless of the genesis of sediments. Pollen brought from adjacent territories does not have a significant effect on the composition of pollen spectra. The spectra from soil deposits in the southeastern part of the island are represented by heather pollen; in the southwestern part, by tree pollen, mostly Siberian dwarf pine, alder, and birch pollen. Among nonarborescent pollen, Asteraceae and Ericaceae are dominant. The pollen spectra obtained from pioneer soil in the western part of the island consist of club moss spores (Lycopodium clavatum), which represent communities on overgrown rockfall deposits. The assemblages of the surface layer of peatlands contain large amounts of sedge and grass pollen. The pollen spectra from alluvial silts represent the vegetation of small valleys, where alder, dwarf pine, and Erman’s birch along the sides are common. The pollen spectra from the sediments of small lakes represent local biotic communities very well. Allochthonous pollen of dark coniferous and broad-leaved trees is present in the spectra in small quantities, except for two samples. This pollen was brought from the southern islands, including those of Japan. The data obtained can be used for paleogeographic reconstructions in the analysis of the formation of pollen spectra on small oceanic islands.
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37

Merrifield, John. "Assessing the Market Metaphor for School Systems—Market Failure versus Political Process Failure: Comment on Brent Beal's and Heather Olson Beal's “Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League”." Journal of School Choice 7, no. 4 (2013): 498–504. http://dx.doi.org/10.1080/15582159.2013.839914.

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38

Maria, Kuznetsova. "Seasonal dynamics of flowering of Calluna vulgaris (L.) Hull and its cultivars in conditions of Kyiv regarding to peculiarities of the flower structure." ScienceRise:Biological Science, no. 2(17) (April 30, 2019): 10–13. https://doi.org/10.15587/2519-8025.2019.165608.

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<strong>The aim of our study&nbsp;</strong>was to research the connection between the flower structure and the duration of flowering of Calluna vulgaris&nbsp;(L.)&nbsp;Hull and its cultivars. Our tasks were to investigate the flower structure of bud bloomers and double-flowered Calluna vulgaris&nbsp;(L.)&nbsp;Hull cultivars, to compare it with the structure of C. vulgaris flower; to analyze the data of phenological observations of C. vulgaris&nbsp;and its 10 cultivars flowering phase during 2015&ndash;2018. <strong>The methods&nbsp;</strong>were phenological observations and microscopic examinations. <strong>Results.</strong>&nbsp;Common features for C. vulgaris and cultivars concerning to their flowering are racemose inflorescences, an arrangement of flowers, acropetal succession. The flower structure of &lsquo;Dirry&rsquo;, &lsquo;Mullion&rsquo;, &lsquo;Golden Carpet&rsquo;, &lsquo;Winter Red&rsquo; is similar to that of C. Vulgaris. Among this group, &lsquo;Winter Red&rsquo; finishes blooming the first and &lsquo;Dirry&rsquo; is the last due to its compound inflorescence. An increased number of petals, full sterility and long flowering period characterize flowers of double-flowered cultivars. Bud bloomers &lsquo;Alicia&rsquo;, &lsquo;Bonita&rsquo; belong to f.&nbsp;diplocalyx Jansen. They are characterized by different flowering periods. &lsquo;Alicia&rsquo; blooms the longest (85&plusmn;7 days) among investigated C. vulgaris cultivars and &lsquo;Bonita&rsquo; blooms about 53 days. <strong>Conclusions.</strong>&nbsp;C. vulgaris cultivars that have the same flower structure as species begin to bloom, as well as common heather, in the third decade of July. The duration of C. vulgaris cultivars flowering period depends also on the peculiarities of the inflorescence structure. Therefore, in order to predict the duration of cultivars flowering, it is necessary to study the features of their inflorescences structure. Double-flowered cultivars are worth to be used more often in gardening due to their high decorativeness and long flowering period. The issue of preserving the color of bud bloomers flowers needs further research. When using the cultivars of C.&nbsp;vulgaris with different types of flowers and duration of flowering, we can create landscapes of high and long decorative features
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Singh, Surinder, Alok Jejusaria, Jaspreet Singh, Munish Vashishath, and Dinesh Kumar. "Comparative study of titanium, platinum, and titanium nitride thin films for micro-elecrto mechanical systems (MEMS) based micro-heaters." AIP Advances 12, no. 9 (2022): 095202. http://dx.doi.org/10.1063/6.0001892.

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This paper presents a comparative study of titanium (Ti), platinum (Pt), and titanium nitride (TiN) micro-electro mechanical systems based micro-heaters. In the present study, a common geometry and thin film thicknesses were selected to achieve comparable base resistances for all three microheater materials. Titanium, platinum, and titanium nitride thin films are deposited using DC magnetron sputtering, E-beam evaporation, and reactive DC magnetron sputtering techniques, respectively, and deposited thicknesses were verified using scanning electron microscopy. Mechanical properties such as Young’s modulus and hardness were also evaluated using nano-indentation. Later, the micro-heaters were fabricated, packaged, and characterized. The thermal coefficient of resistance (TCR) was found to be 4146, 2641, and 487 ppm/°C for Ti, Pt, and TiN micro-heaters, respectively. Power–temperature (P–T) characterization showed that the power required to reach the set temperature is comparable for all the above micro-heater materials. The TiN micro-heater exhibits a linear voltage–current (V–I) characteristic compared to platinum and titanium micro-heaters. The temperatures measured using infra-red imaging were comparable to those calculated by TCR measurements. Furthermore, thermal stability studies have been performed on all micro-heaters for 110 h. TiN microheaters were found to be more stable and resilient to external environmental conditions than Ti and Pt microheaters because of their lower TCR values.
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40

Kukal, Olga. "Winter mortality and the function of larval hibernacula during the 14-year life cycle of an arctic moth, Gynaephora groenlandica." Canadian Journal of Zoology 73, no. 4 (1995): 657–62. http://dx.doi.org/10.1139/z95-077.

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Larvae of the arctic moth Gynaephora groenlandica stop feeding and spin silk hibernacula before the peak of summer season in the Canadian High Arctic Archipelago. This study examines the function of these hibernacula in relation to the biotic and abiotic mortality factors of parasitism and temperature. Winter mortality of 10% among larvae in cages on the tundra was compared with previous results on parasitism (56% mortality). Prior to winter, the cages were used to record larval behaviour and the location of hibernacula. The majority of the larvae (81%) spun hibernacula, most of which were concealed between the stems of arctic heather, Cassiope tetragona. Fewer hibernacula were found on the primary host plant, arctic willow, Salix arctica, than on C. tetragona or Dryas integrifolia, which formed the dominant plant cover. Nearly one-half of all the larvae that spun hibernacula made joint hibernacula with other larvae. Frequency of larvae sharing hibernacula declined with increasing numbers of larvae per cage. At low population density about half of the larvae occupied communal hibernacula, whereas only one-quarter of the larvae at high density shared hibernacula. In most cases only 2 larvae spun a common hibernaculum, 3 larvae shared hibernacula less frequently, and greater numbers of larvae were rarely found in a single hibernaculum. Unlike the high excess body temperatures usually achieved through thermoregulation by feeding larvae and pupae, temperatures within hibernacula were nearly identical with those of the surrounding substrate over 18 h and rose &lt; 5 °C during the afternoon. This study suggests that larval hibernacula lower summer and winter mortality of G. groenlandica larvae. Hibernacula are an effective barrier to parasitism, which is the primary mortality factor. Furthermore, the behavioural shift from feeding to spinning hibernacula may prevent energy depletion by inducing metabolic depression during mid to late summer, which may be essential for winter survival.
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Jung, Dong Geon, Junyeop Lee, Jin Beom Kwon, Bohee Maeng, Hee Kyung An, and Daewoong Jung. "Low-Voltage-Driven SnO2-Based H2S Microsensor with Optimized Micro-Heater for Portable Gas Sensor Applications." Micromachines 13, no. 10 (2022): 1609. http://dx.doi.org/10.3390/mi13101609.

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To realize portable gas sensor applications, it is necessary to develop hydrogen sulfide (H2S) microsensors capable of operating at lower voltages with high response, good selectivity and stability, and fast response and recovery times. A gas sensor with a high operating voltage (&gt;5 V) is not suitable for portable applications because it demands additional circuitry, such as a charge pump circuit (supply voltage of common circuits is approximately 1.8–5 V). Among H2S microsensor components, that is, the substrate, sensing area, electrode, and micro-heater, the proper design of the micro-heater is particularly important, owing to the role of thermal energy in ensuring the efficient detection of H2S. This study proposes and develops tin (IV)-oxide (SnO2)-based H2S microsensors with different geometrically designed embedded micro-heaters. The proposed micro-heaters affect the operating temperature of the H2S sensors, and the micro-heater with a rectangular mesh pattern exhibits superior heating performance at a relatively low operating voltage (3–4 V) compared to those with line (5–7 V) and rectangular patterns (3–5 V). Moreover, utilizing a micro-heater with a rectangular mesh pattern, the fabricated SnO2-based H2S microsensor was driven at a low operating voltage and offered good detection capability at a low H2S concentration (0–10 ppm), with a quick response (&lt;51 s) and recovery time (&lt;101 s).
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42

Dudkiewicz, Edyta, and Paweł Szałański. "A review of heat recovery possibility in flue gases discharge system of gas radiant heaters." E3S Web of Conferences 116 (2019): 00017. http://dx.doi.org/10.1051/e3sconf/201911600017.

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Heating of large-cubage buildings accounts for significant share of energy consumption. The radiant heating system using gas heaters is a common solution for large-cubage halls and is considered to be energy efficient. There is a possibility of additional heat energy recovery from the flue gases of gas radiant heaters because new solutions were introduced to the market. Furthermore heat recovery consists the most promising solution and develop during the recent years rapidly. On the other hand, few works have been dedicated to heat recovery from exhaust gas but none of them consider exhaust gas from radiant heaters. Exhaust gas temperature depends on the type and efficiency of the gas heater. The selection of both the type of radiant heaters and the heat recovery system requires many factors to be taken into account. This study consider possibilities for application of different heat exchangers in exhaust gases system of gas radiant heaters. The authors propose to classify exhaust gas heat recovery systems in dependence on intermediary medium: water/air, gas heaters type: ceramic/tube and number (single/group) and their mounting location.
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43

Charbonneau, Amanda, Arthur Brady, Tanner Coon, et al. "Abstract 1064: Cancer data aggregator: a new cancer data discovery tool." Cancer Research 85, no. 8_Supplement_1 (2025): 1064. https://doi.org/10.1158/1538-7445.am2025-1064.

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Cancer research data is generated and managed in silos. Data repositories frequently use different models and vocabularies to describe their data holdings, and many specialize in certain data types, necessitating that data from a large integrative project be spread across several repositories. For researchers who want to reuse existing cancer data, just navigating this ecosystem of repositories, formats and models can be overwhelming. The Cancer Data Aggregator (CDA) is a new free National Cancer Institute (NCI) service that aims to increase the discoverability of cancer datasets by making them searchable from a common interface, using a single model and vocabulary. We combine metadata for thousands of studies hosted at multiple data repositories across the NCI, and make that metadata available for search from a unified database, so researchers can more easily find and reuse existing cancer research data. The CDA ensures that researchers can find what they’re looking for using a single set of search terms by thoroughly cleaning, harmonizing, and cross-referencing the study metadata. This allows researchers to find subjects that have participated in multiple studies, discover data from a disease that was originally described in different ways at each repository, or compile all the data from a large consortium project like CPTAC - no matter how fragmented it ended up. With the CDA, one set of search terms can return results from data repositories including the Genomic Data Commons, the Proteomic Data Commons, the Imaging Data Commons, Cancer Data Services, and the Integrated Canine Data Commons. Results are displayed in a simple table format (tsv) that is compatible with all standard spreadsheet apps (Excel, Google sheets, Numbers, etc) or loaded directly for analysis in a Jupyter notebook. Results include relevant clinical, phenotypic, genotypic values and provenance details, as well as information about where data files can be downloaded from using the GA4GH DRS API. The Cancer Data Aggregator publishes a new release at the end of each month, and only publishes public data. This ensures that all researchers can use the CDA anonymously without any special privileges, and can always expect data to be up to date. Non-computational users can search the CDA using fill-in-the-blank style queries, while power users can create software for custom searches using our Python library. Visit https://cda.readthedocs.io/ to get started. Citation Format: Amanda Charbonneau, Arthur Brady, Tanner Coon, Rachel Kutner, Surya Saha, Katherine Thayer, Alexander Baumann, Todd Phil, Henry Schaefer, Heather Creasy, Jack DiGiovanna, David Pot, Bing-Xing Huo. Cancer data aggregator: a new cancer data discovery tool [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 1064.
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44

Zois, Christos, and Vassilis Pergantis. "An (un)common remedy to Indigenous communities’ subsistence: revisiting Traditional Knowledge Commons." Journal of Human Rights and the Environment 14, no. 1 (2023): 27–48. http://dx.doi.org/10.4337/jhre.2023.01.02.

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Indigenous Traditional Knowledge (ITK) has been at the centre of heated debates about patent and intellectual protection for a long time. Efforts to normatively regulate the protection of ITK are imbued by a property-based logic associated most prominently with intellectual property regimes, which focus primarily on its economic value. However, such an approach collides with the spiritual, cultural and sacred character of Indigenous Traditional Knowledge. This article aims to provide an alternative for ITK protection through the revamping of the Traditional Knowledge Commons (TKC) concept. It elucidates those TKC traits beneficial to Indigenous communities and identifies potential challenges associated with TKC implementation. The article highlights instances of successfully enacted TKC as evidence of the economic and social capacity of such communitarian schemes, which can further empower Indigenous communities. Lastly, the article explores the viability of establishing a commons-alike ITK management regime on a global scale given the divergent views and aspirations both of communities providing ITK and potential ITK users.
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45

Carpenter, Brittany L., Jacqueline D. Peacock, Kyle Dubiak, Heather Fecteau, and Robert Carlson. "1354. Antibiotic Resistance and Coinfections Among Women with Sexually Transmitted Infections." Open Forum Infectious Diseases 8, Supplement_1 (2021): S764. http://dx.doi.org/10.1093/ofid/ofab466.1546.

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Abstract Background Sexually transmitted infections (STIs) represent a growing epidemic, particularly among America’s youth. Traditional single or dual organism STI testing is limited in its utility compared to PCR panel-based vaginitis testing. PCR panel testing can identify up to 99% of vaginitis associated organisms, while simultaneously providing information about antibiotic resistance. Methods We analyzed 10,011 vaginosis panel cases released between April 2020 and May 2021. The PCR-based vaginosis panel consists of organisms associated with bacterial vaginosis, aerobic vaginitis, yeast infections, STIs, and Lactobacillus species. This panel simultaneously detects evidence of antibiotic resistance for nine classes of drugs. Results Of 9405 cases from vaginal swabs, 618 (6.8%) were positive for at least one STI including Chlamydia trachomatis (CT), Haemophilus ducreyi, Herpes Simplex Virus 1 or 2 (HSV2), Neisseria gonorrhoeae (NG), and/or Trichomonas vaginalis. Of 603 urine samples, 7.6% were positive for at least one STI and represented a younger population. Patients younger than age 25 (33% of the cohort) were disproportionately affected by STIs, consistent with CDC findings. About 50% of all positive STI cases were in patients under 25. Evidence of bacterial vaginosis was also present in 89% of CT and NG cases, and 75% of HSV2 cases. Strikingly, we found the presence of an antibiotic resistant marker(s) to first line treatment in 76.2% of CT and 19.3% of NG cases. Conclusion Our data illustrates the advantages of utilizing a PCR-panel approach to STI detection over a targeted approach for individual organisms. Coinfections with bacterial vaginosis were common and if left unidentified, patients may receive incomplete treatment. Additionally, our data suggests that antibiotic resistance testing is imperative for effective treatment planning and antibiotic stewardship in suspected STI cases. Disclosures Brittany L. Carpenter, PhD, NxGen MDx (Employee) Jacqueline D. Peacock, PhD, MB(ASCP)CM, NxGen MDx (Employee) Kyle Dubiak, PhD, NxGen MDx (Employee) Heather Fecteau, MS, LCGC, NxGen MDx (Employee) Robert Carlson, MD, FCAP, NxGen MDx (Employee)
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46

Kryuchenko, N. O. "BIOGEOCHEMISTRY OF FLUORINE IN SOILS, WILD BERRIES AND MUSHROOMS OF THE SVYDOVETS MASSIF OF THE CARPATHIAN BIOSPHERE RESERVE." Mineralogical Journal 46, no. 4 (2024): 71–80. https://doi.org/10.15407/mineraljournal.46.04.071.

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The results of research on the content of water-soluble fluorine in soils, berries of plants of the heather family, and mushroom fruiting bodies are presented. These are plants — Vaccínium vítis-idaéa, Oxycoccus, Vaccinium uliginosum, Empetrum nigrum and mushrooms — Leccinum aurantiacum, Leccinum scabrum, Russula Pers., which grow in the mid-mountain zone of the Svydovets massif (Mountain Blyznytsia) of the Carpathian Biosphere Reserve (KBR). Fluoride analyzes were performed using the spectrometric method with alizarin-complexon on a Specol 11 spectrophotometer. It was found that the berries of Vaccínium vítis-idaéa contain 5 times more fluoride than the berries of Empetrum nigrum (14.1 mg/kg and 2.9 mg/kg, respectively), the berries of Vaccinium uliginosum and Oxycoccus have approximately the same content — 10—10.7 mg/kg. In the fruiting bodies of mushrooms, the highest content of fluorine is found in Russula Pers. — 16.1 mg/kg, Leccinum aurantiacum — 11.4 mg/kg, Leccinum scabrum — 8.1 mg/kg. According to the coefficient of biological absorption (Ах — the supply of fluorine from the soil to berries and mushrooms), the following series was revealed (from larger to smaller): the berries of Vaccínium vítis-idaéa are characterized by a strong biological accumulation of fluorine (10—15), the berries of Oxycoccus and Vaccinium uliginosum are weak accumulation (8—12), Empetrum nigrum berries — medium and weak capture (0.2—3); mushrooms — Russula Pers. and Leccinum scabrum have strong accumulation (10—15), Leccinum aurantiacum — weak accumulation (8—11). These series coincide with the fluoride content in berries and mushrooms. That is, the majority of fluorine in the berries and mushrooms of KBR comes from the soil, which allows us to draw conclusions about the purity of atmospheric air in relation to fluorine. Correlations between F and other chemical elements — Ca, Fe, Mg, P, K, Na and H2O, as well as nutrients — mono- and disaccharides (sugar), vitamin C in berries and mushrooms were traced. Common features were revealed: strong (R2 &gt;0.8) negative correlation: F — Ca, F — H2O, F — vitamin C; strong positive relationship: F—P.
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47

Gómez, C., P. Alejandro, and F. Montes. "Phenological characterization of Fagus sylvatica L. in Mediterranean populations of the Spanish Central Range with Landsat OLI/ETM+ and Sentinel-2A/B." Revista de Teledetección, no. 55 (June 23, 2020): 71. http://dx.doi.org/10.4995/raet.2020.13561.

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&lt;p&gt;The Spanish Central Range hosts some of the southernmost populations of &lt;em&gt;Fagus sylvatica&lt;/em&gt; L. (European beech). Recent cartography indicates that these populations are expanding, going up-streams and gaining ground to oak forests of &lt;em&gt;Quercus pyrenaica &lt;/em&gt;Willd., heather-lands, and pine plantations. Understanding the spectral phenology of European beech populations—which leaf flush occurs earlier than other vegetation formations—in this Mediterranean mountain range will provide insights of the species recent dynamics, and will enable modelling its performance under future climate oscillations. Intra-annual series of 211 Landsat OLI/ETM+ images, acquired between April 2013-December 2019, and 217 Sentinel-2A/B images, acquired between April 2017-December 2019, were employed to characterize the spectral phenology of European beech populations and five other vegetation types for comparison in an area of 108000 ha. Vegetation indices (VI) including the Normalized Difference Vegetation Index (NDVI) and Tasseled Cap Angle (TCA) from Landsat, and the NDVI and Enhanced Vegetation Index (EVI) from Sentinel-2 were retrieved from sample pixels. The temporal series of these VI were modelled with Savitzky-Golay and double logistic functions, and assessed with TIMESAT software, enabling the parametric characterization of European beech spectral phenology in the area with the start, length, and end of season, as well as peak time and value. The length of beech phenological season was similar when portrayed by Landsat and Sentinel-2 NDVI time series (214 and 211 days on average for the common period 2017-2019) although start and end differed. Compared with NDVI counterparts the TCA season started and peaked later, and the EVI season was shorter. Sentinel-2 NDVI peaked higher than Landsat NDVI. The European beech had an earlier (21 days on average) start of season than competing oak forests. Joint analysis of data from the virtual constellation Landsat/ Sentinel-2 and calibration with field observations may enable more detailed knowledge of phenological traits at the landscape scale.&lt;em&gt;&lt;/em&gt;&lt;/p&gt;
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48

Biryukov, A. B., A. N. Lebedev, and K. D. Kaminsky. "Study of the characteristics of combined flue gas deep cooling devices on hot water boilers of housing and communal services system." Vestnik IGEU, no. 5 (October 31, 2024): 31–41. http://dx.doi.org/10.17588/2072-2672.2024.5.031-041.

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One of the ways to increase the efficiency of hot water boilers of the housing and communal services system is the deep cooling of combustion products to temperatures below the dew point temperature. Currently, there are a number of studies on the use of condensation economizers and air heaters of various types to solve this problem. The use of such devices makes it possible to reduce the temperature of combustion products and, thus, increase the heat utilization coefficient, reduce fuel consumption. The use of combined flue gas cooling devices seems particularly promising, but the parameters of their operation have not yet been studied. In this regard, the development and study of the parameters of such devices are relevant. Using the techniques to design heat exchangers, a set of thermal calculations has been performed to study the characteristics of a combined deep cooling system for combustion products after a hot water boiler of the housing and communal services system, represented by an air heater and a condensation economizer. It is considered that one part of the flue gases after the air heater is sent to the economizer, and the other part goes through the bypass, bypassing the economizer, and then meets the combustion products coming out of it. The distribution of the combustion product flow before the economizer is based on the need to ensure the temperature of the mixed flow after the economizer at 70 °C. For the most common hot water boiler in the housing and communal services system of the TVG-8M type, the authors have been established the dependence of the heat transfer coefficients, the surface area of the heat exchangers and other parameters of the deep cooling system of the exhaust gases on the set value of the temperature of the combustion products after the air heater. It has been established that the proposed scheme of a combined deep cooling system for combustion products makes it possible to improve the technical and economic performance of the boiler by reducing fuel consumption. It is proved that the smoke temperature after the air heater for this type of the boiler should not be very low (not lower than 115–130 °C), since it dramatically increases the heat flow with a decrease in the average logarithmic temperature difference and leads to an increase not only in the temperature of the heated air, but also in the surface area of the air heater.
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49

Crawford, R. H., V. Paton-Cole, R. Turnbull, E. Fitzgerald, A. Michalewicz, and J. Garber. "Trends in residential sustainability measures in the state of Victoria." IOP Conference Series: Earth and Environmental Science 1101, no. 2 (2022): 022018. http://dx.doi.org/10.1088/1755-1315/1101/2/022018.

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Abstract Buildings require a significant quantity of energy and water during their operation. Solar water heaters and rainwater tanks have become increasingly common to reduce the demand for fossil-fuel based energy and mains water within buildings. Since 2006, the Victorian Building Authority has required either a rainwater tank or solar water heater to be installed in any new house built in Victoria, Australia. This research analyses the trend in adoption of these two systems using data from building permits issued from 2006 to 2019. This shows that despite an initial preference for rainwater tanks, solar water heaters have been the preferred choice. This preference was found to be greatest for projects costing from $200k-$600k and for allotment areas smaller than 500 m2. Preference for rainwater tanks tended to increase in line with an increase in project cost and allotment area, and this preference was found to be most common in metropolitan areas. This study provides insight into the opportunities for further adoption of solar water heaters and rainwater tanks, including using information at the LGA level to develop specific business opportunities or to inform policy, such as alternative water efficiency solutions for households where allotment area may limit rainwater tank adoption.
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50

Murali, Shivani Jagannathan, Bharath Kumar Karre, Cristina Ivan, et al. "Abstract 4761: The ERBB4 exon skipping isoform JMA-CYT2 is the dominant isoform of ERBB4 gene fusions." Cancer Research 85, no. 8_Supplement_1 (2025): 4761. https://doi.org/10.1158/1538-7445.am2025-4761.

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Abstract Background: ERBB4, a member of the ERBB family of receptor tyrosine kinases, has received less attention than its counterparts, ERBB1 (EGFR), ERBB2 (HER2) and ERBB3(HER3), despite its established involvement in oncogenesis and its potential as a therapeutic target. While the role of ERBB4 and its isoforms in neuronal development is well understood, mutations and fusions of ERBB4 have been linked to several types of cancer, however they have not been fully explored. Further research into ERBB4 fusions and their oncogenic mechanisms is essential for advancing targeted therapies. Methods: We performed a comprehensive analysis of ERBB4 fusions using next-generation sequencing (NGS) data from a total of 216, 176 formalin-fixed paraffin-embedded (FFPE) tumor samples across various solid tumors. NGS was conducted on DNA isolated from these samples and RNA fusions were detected using whole transcriptome sequencing (WTS). We analyzed patient demographics, fusion partners, ERBB4 isoforms, and co-occurring mutations. Additionally, tumor mutational burden (TMB) was assessed, and data from public bioinformatic resources were used for comparison. Results: ERBB4 fusions were detected in 0.25% of the 24 solid tumor types analyzed, with the highest prevalence observed in OSEC, BRCA, BLCA, UTNE, and NSCLC. Notably, 63.1% of ERBB4 fusions involved the 3' end of the gene and included various fusion partners. The most common fusion partner was IKZF2:ERBB4, accounting for 58.2% of cases. Exon 2 was identified as the most frequent breakpoint in ERBB4 fusions. As a result, 5' ERBB4 fusions retain only the signal peptide, while 3' fusions lose the signal peptide, which may impair translocation to the cell membrane. The most common isoform observed in ERBB4 fusions was the JMa-Cyt2 isoform, seen in over 83% of cases. This isoform skips exon 26, which contains a PI3K phosphorylation site critical for ubiquitination and degradation. Further analyses revealed a significant upregulation of ERBB4 expression in ERBB4 fusion positive cases in BLCA(P&amp;gt;0.001), OSEC(P&amp;gt;0.001), and NSCLC(P&amp;gt;0.001). Pathway analyses revealed upregulation of Myc targets indicating ERBB4-ICD-STAT5A complex in promoting cell proliferation. Co-occurring mutations are enriched in TP53, PIK3CA, and TERT in ERBB4 fusions. Conclusion: Our study highlights the frequent occurrence of ERBB4 fusions across various cancer types, with IKZF2 being the most common fusion partner. The prevalence of the ubiquitination-resistant JMa-Cyt2 isoform and the retention of cytoplasmic (kinase) domain in many fusions suggest that ERBB4 fusions may contribute to oncogenesis through a STAT5A-dependent mechanism, independent of PI3K. These findings underscore the potential of ERBB4 fusions as therapeutic targets and suggest that gamma-secretase inhibitors could be a promising treatment option for patients with these fusions. Citation Format: Shivani Jagannathan Murali, Bharath Kumar Karre, Cristina Ivan, Chao Sima, Asfetaw Abera, David Spetzler, Milan Radovich, Heather O'neill, Ravi Chakra Turaga. The ERBB4 exon skipping isoform JMA-CYT2 is the dominant isoform of ERBB4 gene fusions [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 4761.
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