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Journal articles on the topic 'Comorbid pathology'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Tribuntseva, L. V., A. V. Budnevsky, Yu S. Ivanchuk, Ya S. Shkatova, and R. E. Tokmachev. "COMORBID PATHOLOGY IN PATIENTS WITH BRONCHIAL ASTHMA: LITERATURE REVIEW." NAUKA MOLODYKH (Eruditio Juvenium) 9, no. 1 (2021): 136–46. http://dx.doi.org/10.23888/hmj202191136-146.

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The article contains a literature review that presents the results of studies of the prevalence of comorbidy in patients with bronchial asthma (BA), as well as the gender- and age-related characteristics of comorbidity in such patients. More than half of asthma patients suffer from the comorbid pathology, which negatively affects the clinical course of asthma, as well as the quality of life. The number of chronic comorbid diseases increases with age, on average to 5 comorbid conditions in BA patients aged 75 years and older. The most common diseases, the prevalence of which increases with age,

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Boyko, V. V., K. Y. Parkhomenko, V. V. Nikonov, O. E. Feskov, and O. E. Gavrikov. "Comorbid pathology in herniology." EMERGENCY MEDICINE 17, no. 1 (2021): 14–20. http://dx.doi.org/10.22141/2224-0586.17.1.2021.225709.

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In recent decades, there has been an aging population worldwide with an increasing proportion of the elderly and senile, leading to a significant increase in the prevalence of a variety of pathologies, especially cardiovascular disease, overweight and obesity, diabetes, neoplastic and dysplastic diseases, and diseases that require surgical treatment. The negative impact on health significantly increases in the presence of several diseases, which creates qualitatively new conditions that cannot be explained by the mechanical sum of the impact of individual diseases. The presence of concomitant

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Vertkin, A. L., A. S. Sycheva, A. V. Nosova, G. U. Knorring, and G. V. Zavyalov. "Metabolic therapy for comorbid pathology." Medical alphabet 1, no. 19 (2020): 19–23. http://dx.doi.org/10.33667/2078-5631-2020-19-19-23.

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Demographic changes, the increasing frequency of comorbidity make us pay close attention to the prescribed therapy and control of drug to drug interactions. The use of polymodal drugs with pleiotropic effects that affect the key points of development of comorbid pathology may be promising.

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Saranyuk, R. V., and A. V. Polonikov. "Psoriasis: analysis of comorbid pathology." Russian Journal of Clinical Dermatology and Venereology 24, no. 1 (2025): 16. https://doi.org/10.17116/klinderma20252401116.

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Background. Chronic nature of course and presence of systemic inflammation in psoriasis are accompanied by the development of a great number of comorbid disorders, which not only lead to social maladjustment, but also directly affect patients’ survival. For clinicians, diagnostic search of co-occuring disorders in psoriasis during routine practice is often difficult due to their great diversity, different incidence and pronouncement of associations with the main disease. Objective. To study the structure of comorbid disorders in patients with psoriasis. Material and methods. A number of patien

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Afanaseva, A. D., L. V. Shcherbakova, V. V. Gafarov, V. S. Shramko, D. V. Denisova, and Yu I. Ragino. "Characteristics of behavioral and socioeconomic risk factors for noncommunicable diseases in young people with comorbidities." Cardiovascular Therapy and Prevention 23, no. 12 (2025): 4096. https://doi.org/10.15829/1728-8800-2024-4096.

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Aim. To analyze behavioral and socioeconomic risk factors for noncommunicable diseases in young people with comorbidities.Material and methods. The population sample included 1415 people. Comorbid pathology was considered a combination of ≥3 diseases. Comorbid pathology was detected in 105 examined people.For comparison with comorbid patients, a group of healthy individuals without any of the studied diseases was formed (n=162).Results. When assessing the main socioeconomic and behavioral characteristics, healthy individuals more often report a good self-perceived health compared to individual

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Lawson, Ben D., Angus H. Rupert, and Amanda M. Kelley. "Mental Disorders Comorbid with Vestibular Pathology." Psychiatric Annals 43, no. 7 (2013): 324–27. http://dx.doi.org/10.3928/00485713-20130703-07.

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Sarsenbaeva, G. I., and A. I. Kim. "Comorbid pathology in pediatric cardiac surgery." CHILDREN’S HEART AND VASCULAR DISEASES 15, no. 4 (2018): 213–18. http://dx.doi.org/10.24022/1810-0686-2018-15-4-213-218.

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Shahinian, V. R., I. V. Filchakov, N. V. Kharchenko, et al. "IS BLASTOCYST INVASION A COMORBID PATHOLOGY?" Medical Parasitology and Parasitic Diseases, no. 3 (August 2021): 51–58. http://dx.doi.org/10.33092/0025-8326mp2021.3.51-58.

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Blastocystis spp. - unicellular protozoa, widespread in the human population, the clinical significance of which is being discussed. The aim and objectives of the work: to study the prevalence of Blastocystis spp. in patients with gastrointestinal diseases and individuals with immunodeficiency states (HIV-positive patients), to determine the presence of specific gastrointestinal symptoms in blastocyst invasion (BI). Testing for Blastocystis spp. persons who have not been diagnosed with gastrointestinal tract disease (253) - comparison group (CG); patients who underwent inpatient or outpatient

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Dynnik, V. O., N. V. Bagatska, O. O. Dynnik, O. G. Verchoshanova, and H. O. Havenko. "Comorbid pathology issues in pediatric gynecology." Modern pediatrics. Ukraine, no. 8(128) (December 28, 2022): 32–36. http://dx.doi.org/10.15574/sp.2022.128.32.

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The problems of diagnosis, therapeutic tactics and medical prognosis in comorbid, polymorbid pathology stand out among the most actual problems of modern health care. Purpose - to study the frequency and nature of comorbid conditions in patients with pubertal abnormal uterine bleeding (PAUB). Materials and methods. The study included 342 girls aged 11-17 suffering from PAUB. All patients were examined by a multidisciplinary team of doctors. Results. It has been shown that menstrual irregularities are combined with other somatic, mental and endocrine pathologies in the vast majority of patients

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Brynina, A. V., D. R. Gimhan, and A. I. Wickramage. "COMORBID CONDITIONS IN PSORIASIS." Journal of the Grodno State Medical University 21, no. 1 (2023): 12–18. http://dx.doi.org/10.25298/2221-8785-2023-21-1-12-18.

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Psoriasis is a chronic dermatosis of a multifactorial nature with a dominant role in the development of genetic factors, characterized by hyperproliferation of epidermal cells, impaired keratinization, and inflammation in the dermis. Currently, its prevalence in the population is from 0.1 to 7%, and among people hospitalized in dermatological hospitals – from 25 to 40%. In the scientific literature, the issue of considering psoriasis as a systemic disease is widely discussed, which includes damage not only to the skin, but also to other organs and systems. Thus, the indicated problems of combi

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Ustinova, Olga Y., Nina V. Zaitseva, Vitalii G. Kostarev, Elena M. Vlasova, Alyona A. Vorobyova, and Alexandr E. Nosov. "Analysis of comorbid pathology in oil producers." Hygiene and sanitation 100, no. 5 (2021): 464–70. http://dx.doi.org/10.47470/0016-9900-2021-100-5-464-470.

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Aim of the study. To analyze the patterns of the comorbidity pathology formation in employees occupied in oil production. Materials and methods. Observation group - 292 employees of the oil production enterprise (100% men). The average age was 39.4 ± 10.6 (20-65) years. Average work experience is 13.1 ± 9.6 (3-22) years. The comparison group included 65 employees working in the management of the enterprise. The average age is 40.2 ± 9.8 (20-65) years. Average work experience is 18.5 ± 9.5 (5-23) years. Observation group - 292 oil and gas production operators (OGP) - 100% men. The study involve

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Zaytseva, N. S., A. D. Bagmet, V. G. Kokoev, and A. V. Popov. "NOSOLOGICAL CHARACTERISTICS OF COMORBID PATHOLOGY IN COMBATANTS." Современные проблемы науки и образования (Modern Problems of Science and Education), no. 6 2020 (2020): 100. http://dx.doi.org/10.17513/spno.30343.

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Orlova, E. A., Yu A. Kandrashkina, E. Yu Trushina, and E. M. Kostina. "Patient with comorbid pathology: is ASIT possible?" Allergology and Immunology in Paediatrics, no. 2 (June 24, 2024): 82–88. http://dx.doi.org/10.53529/2500-1175-2024-2-82-88.

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Introduction. ASIT is characterized by a high safety profile, however, when prescribing ASIT, indications and certain contraindications should be taken into account, knowledge of which is mandatory for every practicing allergist. In recent years, clinical contraindications to ASIT have been revised due to the publication of the Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI). The decision to prescribe ASIT is based on an assessment of the individual patient’s condition, analysis of indications, consideration of contraindications to ASIT, assessment of concomit

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Surkova, L., A. Strinovich, O. Budnik, and A. Bahtina. "Possibilities of quantiferon test in detection of latent tb infection." Immunopathology, Allergology, Infectology 2022 (April 1, 2022): 31–34. http://dx.doi.org/10.14427/jipai.2022.2.31.

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Objective: to determine the capabilities of the quantiferon test in detecting latent tuberculosis infection in patients with comorbid pathology. Materials and methods. A retrospective analysis of the quantiferon test results was carried out in 420 patients with suspected tuberculosis or with a hyperergic Mantoux or Diaskintest reaction using the QuantiFERON-TB Gold Plus test system (Qiagen, Germany). Results. Different levels of tuberculosis infection were established in different age groups of patients with comorbid pathology, with a higher infection rate at a young age – 21.42%. The shift of

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Kholodkov, N. I., V. V. Ostroukhov, V. A. Drobyshev та ін. "КЛИНИЧЕСКИЙ СЛУЧАЙ ЭФФЕКТИВНОЙ РЕАБИЛИТАЦИИ ПАЦИЕНТА С КОМОРБИДНОЙ СОСУДИСТОЙ ПАТОЛОГИЕЙ". Sibirskij medicinskij vestnik 7, № 3 (2023): 65–71. http://dx.doi.org/10.31549/2541-8289-2023-7-3-65-71.

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The problem of rehabilitation of patients with multimorbid pathology currently holds its medical and social relevance, due to the complexity of choosing an adequate treatment and predicting possible complications at the hospital stage. This is determined by the predominant monomorbid nature of clinical recommendations, as well as the difficulty of analyzing all risk factors and predicting the outcome of a comorbid disease. The article describes the case of a 60-year-old man with comorbid cerebrocardiovascular pathology, transferred from the palliative department to a rehabilitation center. The

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Mitchenko, Olena I., Kateryna O. Timokhova, and Nataliia M. Chulaievska. "Diagnostic Features and Selection of Hypolipidemic Therapy in Patients with Coronary Artery Disease with “Possible” Familial Hypercholesterolemia." Ukrainian Journal of Cardiovascular Surgery 30, no. 3 (2022): 50–59. http://dx.doi.org/10.30702/ujcvs/22.30(03)/mt041-5059.

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The aim. To optimize the diagnostic algorithm for patients with true “possible” familial hypercholesterolemia (FH) and differential diagnosis with hypercholesterolemia on the background of comorbid endocrinopathies for selection of optimal hypolipidemic therapy. Materials and methods. We examined 130 patients with hypercholesterolemia and comorbid pathology (type 2 diabetes mellitus, hypothyroidism, obesity grade II-III). In each group, subgroups with low-density lipoproteins (LDL) ≥5 mmol/l were selected and followed up on the background of maximum tolerated doses of statins in combinat

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Bakalets, N. F., and O. L. Nikiforova. "ANALYTICAL ASSESSMENT OF OUT-PATIENT TREATMENT OF PATIENTS WITH RHEUMATOID ARTHRITIS." Health and Ecology Issues, no. 4 (December 28, 2016): 36–40. http://dx.doi.org/10.51523/2708-6011.2016-13-4-8.

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Objective: to carry out the analytical assessment of outpatient management of patients with rheumatoid arthritis in real clinical practice and study the structure of comorbid pathology. Material and methods. The medical records of 88 patients have been analyzed at 6 outpatient clinics of Gomel. The Charlson comorbidity index was applied for the quantitative assessment of the comorbid status. Results. The most common provoking factors of the development of rheumatoid arthritis were acute respiratory viral infections and exacerbation of chronic diseases; and the background disease was thyroid pa

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Volkova, Yu V., V. O. Dynnik, S. V. Novokhatska, L. V. Matiusha, and O. H. Verhoshanova. "Vitamin and microelement supply of adolescent girls with menstrual function disorders." Ukrainian Journal of Pediatric Endocrinology, no. 1 (April 6, 2024): 9–14. http://dx.doi.org/10.30978/ujpe2024-1-9.

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Objective — to identify the relationship between changes in the concentration of vitamins A, E, D, magnesium content, and comorbid pathology in adolescent girls with menstrual function disorders. Materials and methods. Examinations involved 237 girls with menstrual function disorders aged 11—18 years. Oligomenorrhea (OM) was diagnosed in 103 patients, and abnormal uterine bleeding (AUB) in 134 girls. Results and discussion. Comorbid pathology was revealed in most patients, regardless of the type of menstrual function disorder. Endocrine system disorders were the most frequent comorbidities. In

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Trukhan, Dmitry I., Yulia S. Chuyanova, and Dmitry G. Makushin. "The problem of urinary incontinence through the prism of comorbidity." Clinical review for general practice 2, no. 9 (2021): 11–23. http://dx.doi.org/10.47407/kr2021.2.9.00103.

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The problem of urinary incontinence is multidisciplinary. Patients with this problem get an appointment with therapists, general practitioners, pediatricians, urologists, gynecologists, neurologists. Real clinical practice is currently characterized by a significant increase in clinical situations, when it is difficult to talk about the presence of only one disease in a patient, and in most clinical cases the patient has a concomitant or combined pathology. Arterial hypertension and diabetes mellitus are among the most common somatic diseases. To analyze the influence of these diseases on the

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Zhdan, V. N., H. S. Khaіmenova, M. Yu Babanina, G. V. Volchenko, and I. V. Ivanitsky. "MODERN APPROACH TOWARDS THE TREATMENT OF COMORBID PATHOLOGY." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 19, no. 2 (2019): 12–15. http://dx.doi.org/10.31718/2077-1096.19.2.12.

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Osteoarthritis (OA) is a common, poly-etiological disease of the joints, the occurrence and development of which is associated with a number of genetic, endogenous (hormonal balance, immune disorders, oxidative stress) and exogenous factors (trauma, overload). The combination of metabolic syndrome (MS) and OA is one of the most pressing medical and social issues for healthcare today. This is due to both their extremely high prevalence and high comorbidity with other conditions and diseases that have a significant impact on the quality of life of patients. The aim of our work was to study the p

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Vasiltseva, O. Ya, and I. N. Vorozhczova. "Glycemic control importance in patients with comorbid pathology." Consilium Medicum 20, no. 10 (2018): 96–100. http://dx.doi.org/10.26442/2075-1753_2018.10.96-100.

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Olyunin, Yu A. "Chronic musculoskeletal pain. Leading symptom or comorbid pathology?" Modern Rheumatology Journal 16, no. 3 (2022): 96–102. http://dx.doi.org/10.14412/1996-7012-2022-3-96-102.

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Current trends in the development of personalized medicine dictate the need to interpret chronic pain as a multifactorial biopsychosocial phenomenon. A comprehensive integrated approach to the management of patients with chronic pain includes nosological diagnostics, assessment of factors that determine the persistence of pain and comorbid pathology, and the use of necessary pharmacological and non-pharmacological methods of treatment. Currently, primarily non-steroidal anti-inflammatory drugs are used for the pharmacotherapy of chronic pain, which is predominantly nociceptive in nature. Melox

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Larkin, V. I., A. A. Bort, T. A. Lisina, A. D. Potasheva, and V. A. Hvostov. "Ischemic stroke in the patients with comorbid pathology." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 118, no. 3 (2018): 15. http://dx.doi.org/10.17116/jnevro20181183215-19.

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Nevzorova, V. A., V. M. Chertok, T. A. Brodskaya, P. A. Selyukova, and N. V. Zakharchuk. "Mitochondrial dysfunction and vascular aging in comorbid pathology." Pacific Medical Journal, no. 1 (March 25, 2022): 10–16. http://dx.doi.org/10.34215/1609-1175-2022-1-10-16.

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Cardiovascular diseases take a leading position in the structure of mortality in modern society. Most diseases are characterized by uncontrolled processes of oxidative stress, proteolysis, tissue and cellular hypoxia, which cause endothelial dysfunction. Tissue and cellular hypoxia accumulated with mitochondrial reactive forms of oxygen damaging lipoproteins, proteins, nucleic acids plays an important role in the pathogenesis of vascular aging. Cellular aging is characterized by a decrease in the number of mitochondria, a decrease in the number of copies of mitochondrial DNA, and the loss of m

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Chernova, L. "Comorbid pathology in children with autism spectrum disorders." Vrach 32, no. 8 (2021): 50–53. http://dx.doi.org/10.29296/25877305-2021-08-09.

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Derevyanko, Olga S., Liudmila I. Ibragimova, Magomedkerim R. Ragimov, and Tatiana V. Nikonova. "Autoimmune gastritis: comorbid pathology in type 1 diabetes." Diabetes mellitus 21, no. 5 (2018): 404–8. http://dx.doi.org/10.14341/dm9465.

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In recent years noted an increased number of patients with autoimmune diseases (AID), and the special attention deserves combination of several autoimmune pathologies collected in one patient, because such patients requires special tactics of management. Autoimmune diseases of the gastrointestinal tract are less researched and, nevertheless, prognostically unfavorable. Autoimmune gastritis (AIG) has a special place in other stomach diseases, which develops in the aggregate with type 1 diabetes. AIG is a chronic inflammation of the mucous membrane of the body of the stomach, leading to the appe

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Vorotynov, Y. A., R. K. Kantemirova, Z. D. Fidarova, and A. A. Obrezan. "Rehabilitation of patients with comorbid pathology: age specifics." Russian Journal of Geriatric Medicine, no. 4 (December 20, 2024): 263–69. https://doi.org/10.37586/2686-8636-4-2024-263-269.

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INTRODUCTION. A personalized approach to the rehabilitation of patients with coronary heart disease (CHD) and concomitant musculoskeletal disorders (MSDs) is becoming increasingly relevant, especially for older patients. The number of patients with comorbidities is significantly related to age. Older people tend to experience slowly progressive pathological conditions, they gradually develop several diseases, particularly chronic ones, and their ability to compensate and adapt is reduced.OBJECTIVE: To analyze modern methods of cardiac rehabilitation for this group of patients.MATERIALS AND MET

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Khavkin, A. I., A. V. Naletov, E. A. Balakireva, et al. "Comorbid pathology of the gastrointestinal tract in psoriasis." Archives of Pediatrics and Pediatric Surgery 2, no. 3 (2025): 10–14. https://doi.org/10.31146/2949-4664-apps-2-3-10-14.

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Psoriasis is a chronic inflammatory immune-mediated disease associated and often coexisting with another chronic inflammatory pathology associated with impaired immune response. Immuno-inflammatory diseases of the gastrointestinal tract are recorded with high frequency in patients with psoriasis. The data obtained from the studied literature confirm the connection between psoriasis and inflammatory bowel diseases, celiac disease, non-alcoholic fatty liver disease. The presence of common pathogenetic links, side effects from ongoing psoriasis treatment methods, indicates the need for diagnostic

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Kuzmin, N. D., N. V. Ustinova, N. A. Pozdeeva, et al. "Comorbid pathology in children with rare eye diseases." EYE GLAZ 25, no. 2 (2023): 136–43. http://dx.doi.org/10.33791/2222-4408-2023-2-136-143.

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Introduction. It is often very difficult to single out the leading type of a disorder in children, especially with impaired or underdeveloped vision. There is a risk to overlook other types of health restrictions in boarding schools for blind and tender-eyed children. The need to solve the problem of comprehensive support for persons with disabilities is conditioned by the provisions of the Universal Declaration of Human Rights, the UN Convention on the Rights of the Child and the UN Convention on the Rights of Persons with Disabilities.Purpose. To analyze the comorbidity of congenital visual

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Vasyliuk, V. M., V. S. Khabchuk, A. Ya Pavliak, O. Ya Zhurakivska, and A. B. Hrechyn. "Morphologic characteristic of rat myocardium in comorbid pathology." Pathologia 20, no. 2 (2023): 175–81. http://dx.doi.org/10.14739/2310-1237.2023.2.280409.

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Diabetic cardiomyopathy is a serious complication of diabetes mellitus (DM). Aim. Therefore, we aimed to study myocardial changes in adult rats with streptozotocin (STZ)-induced DM exposed to chronic immobilization stress (CIS). Materials and methods. A total of 26 adult albino male rats weighing 180–200 g were examined. All the animals were divided into three groups: Group I included 10 rats with STZ-induced DM exposed to CIS; Group II comprised 10 rats with STZ-induced DM; Group III included 6 intact animals. The samples were collected on the 14th and 56th days of the experiment. Histologica

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Khaisheva, L. A., O. V. Likhachev-Mishchenko, K. A. Khaishev, V. A. Suroedov, and N. V. Drobotya. "Growth stimulating factor in patients with comorbid pathology." South Russian Journal of Therapeutic Practice 6, no. 1 (2025): 66–72. https://doi.org/10.21886/2712-8156-2025-6-1-66-72.

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Objective: to study the level of growth stimulating factor (sST-2) in comorbid patients with ST-segment elevation myocardial infarction (STeMI) who underwent PCI for 36 months. Materials and methods: the study included 191 people, 36.2 + 1.8 months of follow-up, and included the following stages: I stage (hospital) — from the moment of admission to the hospital for myocardial infarction; II stage (outpatient) — repeated visits 12 and 36 months after discharge from the hospital. The patients were divided into three groups: Group 1 — 69 patients with STEMI + hypertension; Group 2 — 67 patients w

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Balandina, T. V., Yu V. Trinitatsky, Z. A. Goncharova, D. S. Korobko, R. E. Gromyko, and Y. Y. Pogrebnova. "Multiple sclerosis and neoplasms: comorbid oncological pathology in patients with multiple sclerosis in the Rostov region." South Russian Journal of Therapeutic Practice 6, no. 2 (2025): 65–71. https://doi.org/10.21886/2712-8156-2025-6-2-65-71.

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Objective: study of the structure of comorbid oncological pathology in patients with MS in the Rostov region. Description of the difficulties of differential diagnosis in patients with neoplasms and identification of features of the course of MS in patients with comorbid oncological pathology, first of all, the rate of increase in disability. Materials and methods: the study included 44 patients with significant comorbid oncological pathology (neoplasms of the central and peripheral nervous system, malignant tumors) using patient questionnaires, laboratory and instrumental research methods. St

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Ivashchenko, Irina E., Marina A. Kuzmenko, Viktoriya V. Popova, and Irina V. Alexandrova. "Analysis of comorbid pathology in patients with occupational chronic obstructive pulmonary disease from exposure to industrial aerosols according to the regional register of Occupational Diseases of the Novosibirsk region." Russian Journal of Occupational Health and Industrial Ecology 62, no. 8 (2022): 507–12. http://dx.doi.org/10.31089/1026-9428-2022-62-8-507-512.

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Introduction. In the course of the work the scientists have conducted an analysis of comorbid pathology was carried out in patients with occupational chronic obstructive pulmonary disease (OCOPD) who underwent inpatient examination at the Clinic of the Novosibirsk Research Institute of Hygiene of Rospotrebnadzor. The study aims to research the frequency and nature of comorbid pathology in patients with OCOPD who underwent inpatient examination at the Clinic of the Novosibirsk Research Institute of Hygiene of Rospotrebnadzor. Materials and methods. In the course of the work we have conducted a

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Melnikova, I. Yu, and E. G. Shapovalov. "Comorbid conditions in pediatric practice." Experimental and Clinical Gastroenterology, no. 6 (October 22, 2024): 169–75. http://dx.doi.org/10.31146/1682-8658-ecg-226-6-169-175.

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The comorbidity is an urgent scientific and practical problem of modern pediatrics. The practical significance of combined pathology in children is determined by its widespread occurrence and universal impact on all aspects of a child’s health and treatment options. In patients with congenital heart defects, outcomes are influenced by numerous non-cardiac and genetic factors. In childhood and adolescent bronchial asthma, concomitant diseases are a common cause of adverse outcomes, such as poor disease control, frequent seizures, decreased quality of life and increased healthcare costs. A stabl

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Malyutina, Natalia, Svetlana Luzina, and Olga Shilcova. "P-151 THE RISK PREDICTION OF COMORBID PATHOLOGY DEVELOPMENT OF LOCOMOTIVE DRIVERS WITH ARTERIAL HYPERTENSION." Occupational Medicine 74, Supplement_1 (2024): 0. http://dx.doi.org/10.1093/occmed/kqae023.0668.

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Abstract Introduction Arterial hypertension and gastrointestinal tract diseases are common diseases and often observed in the same patients. It is expedient to develop a methodology for predicting of a comorbid pathology developing for workers in order to maintain working longevity. Methods Employees (n=127, men) of locomotive crews ofrailways (experience &gt; 10 years) are examined. Laboratory studies: a general blood test, serum concentrations of traditional biochemical parameters, the concentration of individual proteins. Results The obtained data let to develop a mathematical formula f

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Kravchenko, I. E., E. R. Girfanutdinova, N. V. Galeeva, and R. R. Ginyatullin. "Comorbid conditions as extrahepatic manifestations of chronic HCV infection." Infekcionnye bolezni 22, no. 2 (2024): 101–7. http://dx.doi.org/10.20953/1729-9225-2024-2-101-107.

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Chronic hepatitis C virus (HCV) infection is a serious public health problem. In 2022, more than 33.8 thousand cases of chronic hepatitis C virus (HCV) were registered in the Russian Federation, with a total economic burden of RUB 60.9 billion. In addition to liver damage, a significant number of patients with CHC have various comorbid conditions, the development of which may be due to extrahepatic replication of HCV. In clinical practice, it is difficult to prove the association of comorbid pathology with extrahepatic manifestations of HCV. This literature review presents the results of meta-

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Suleymanova, Tamila Rustamovna, Konul Adil kyzy Mamеdova, and Evgeniya Valeryevna Sosnovskaya. "THE EFFECT OF COMORBID PATHOLOGY ON THE COURSE OF SARS-COV-2 INFECTI." Scientific medical Bulletin of Ugra 32, no. 2 (2022): 53–55. http://dx.doi.org/10.25017/2306-1367-2022-32-2-53-55.

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The influence of comorbid conditions on the course of a new coronavirus infection caused by SARS-CoV-2 (COVID-19) is becoming an urgent problem for healthcare. There is more and more information confirming that the severity of COVID-19 depends on the presence of comorbid conditions in the patient. This work is devoted to the analysis of outcomes from covid - 19 in patients with comorbid pathology

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Riku, Yuichi, Mari Yoshida, Yasushi Iwasaki, Gen Sobue, Masahisa Katsuno, and Shinsuke Ishigaki. "TDP-43 Proteinopathy and Tauopathy: Do They Have Pathomechanistic Links?" International Journal of Molecular Sciences 23, no. 24 (2022): 15755. http://dx.doi.org/10.3390/ijms232415755.

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Transactivation response DNA binding protein 43 kDa (TDP-43) and tau are major pathological proteins of neurodegenerative disorders, of which neuronal and glial aggregates are pathological hallmarks. Interestingly, accumulating evidence from neuropathological studies has shown that comorbid TDP-43 pathology is observed in a subset of patients with tauopathies, and vice versa. The concomitant pathology often spreads in a disease-specific manner and has morphological characteristics in each primary disorder. The findings from translational studies have suggested that comorbid TDP-43 or tau patho

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Pavliukovych, Nataliia D., Volodymyr V. Husak, Oleksandr V. Pavliukovych, Vira O. Shuper, Serhii V. Shuper, and Olena M. Husak. "ERYTHROPOIETIN SYNTESIS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON COMORBID PATHOLOGY." Clinical and Preventive Medicine, no. 7 (December 24, 2023): 39–43. http://dx.doi.org/10.31612/2616-4868.7.2023.05.

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Introduction. Decreased production of erythropoietin by the kidneys plays crucial role in the development of anemia in patients with chronic heart failure, especially on the background of comorbid diabetes mellitus type 2. In diabetic patients due to early damage of the kidney vessels and following erythropoietin deficiency anemia develops much earlier than clinically significant decrease of glomerular filtration rate. The aim of the study was to find out possible dependence of changes in the erythropoietinsynthesizing function of the kidneys on the degree of severity of anemic hypoxia i

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Beigel, Elena A., Elena V. Katamanova, and Nataliya V. Efimova. "Risk factors for the development of comorbid diseases of occupational bronchopulmonary pathology." Hygiene and sanitation 101, no. 9 (2022): 1043–48. http://dx.doi.org/10.47470/0016-9900-2022-101-9-1043-1048.

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Introduction. Comorbid diseases in patients with occupational bronchopulmonary pathology determines the severity of the underlying disease. The purpose was to identify risk factors for the development of concomitant diseases in occupational bronchopulmonary pathology in aluminum production workers. Materials and methods. One hundred thirty men with an occupational pathology including chronic obstructive pulmonary disease (COPD), bronchial asthma (BA), chronic non-obstructive bronchitis (CNB) and their combination were examined. Inclusion criteria - male gender, age from 43 years to 72 years, e

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Voronko, Andrii, Olha Selіuk, Alla Buzhenko, et al. "Prolongation of Professional Longevity of Patients with Arterial Hypertension in Military Personnel Participating in Modern Armed Conflicts." Family medicine. European practices, no. 1 (February 28, 2023): 28–34. http://dx.doi.org/10.30841/2786-720x.1.2023.277478.

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Arterial hypertension (AH) without proper treatment can lead to heart attack, stroke, kidney or heart failure, vision impairment and other complications. The determination of effective preventive measures to prolong siutability for military service based on the health status of experienced military persons with existing comorbid pathology is an urgent issue today and a component of national security. The objective: to analyze the effective measures that influence on the prolongation of the suitability for military service of military personnel with AH – the participants in the anti terrorist o

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Polozova, Ella, Vsevolod Skvortsov, Olga Radaykina, et al. "Clinical case of a comorbid patient with arterial hypertension." Spravočnik vrača obŝej praktiki (Journal of Family Medicine), no. 2 (February 1, 2020): 31–39. http://dx.doi.org/10.33920/med-10-2002-04.

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The widespread prevalence of comorbid pathology determines the relevance of this problem. Comorbid pathology due to the interaction of diseases, drug pathomorphism, age characteristics of the patient, significantly changes clinical picture and course of the main nosology, affects severity of complications and their nature, significantly affects quality of life and prognosis of patients. Diagnosis and treatment of many diseases is complicated in the conditions of comorbidity. The article presents a clinical case of a comorbid patient with arterial hypertension from the moment of exposure to ris

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Uryasyev, O. M., Y. A. Panfilov, M. A. Granatkin, and A. A. Pyko. "CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND COMORBIDITY." Journal of Volgograd State Medical University 74, no. 2 (2020): 174–77. http://dx.doi.org/10.19163/1994-9480-2020-2(74)-174-177.

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The article discusses comorbid diseases that occur in chronic obstructive pulmonary disease, which are consideredin the context of «comorbid pathology». The pathogenesis of associated diseases and its relationship with the underlyingdisease is shown.

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Rusina, Robert, Radoslava Bajtosova, Zsolt Cséfalvay, et al. "Comorbid Neurodegeneration in Primary Progressive Aphasia: Clinicopathological Correlations in a Single-Center Study." Behavioural Neurology 2022 (September 8, 2022): 1–14. http://dx.doi.org/10.1155/2022/6075511.

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Introduction. Primary progressive aphasia (PPA) is a clinically variable syndrome manifesting as slow progressive loss of speech and language with multiple underlying neurodegenerative pathologies. Materials and Methods. We included data from nine PPA patients with available autopsies. We then retrospectively reviewed all available medical records, neuropsychology, and MRI results to confirm the corresponding subtypes of PPA and compared them with postmortem neuropathological results. Results. Clinical presentations corresponded to the nonfluent/agrammatic variant in six cases, the semantic va

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Rychkova, S. I., N. I. Kurysheva, A. B. Laver, A. I. Tolmacheva, and R. I. Sandimirov. "Comorbid pathology in children with partial optic nerve atrophy." Russian ophthalmology of children 50, no. 4 (2024): 12–17. https://doi.org/10.25276/2307-6658-2024-4-12-17.

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Purpose.To evaluate the structure of comorbid pathology in schoolchildren with congenital partial optic atrophy. Material and methods. Medical records of 120 children with congenital partial optic nerve atrophy (PONA) and 67 children in the control group without ophthalmopathology were observed and analyzed. Results.Obtained data demonstrated in the group of children with PONA compared with the control group a higher incidence of neurological pathology (14.9% in children with CANV versus 46.7% of children in the control group, p<0.001), as well as mental disorders, musculoskeletal diseases

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Khokhlova, Yu A., L. N. Markelova, and N. E. Titova. "Comorbid diseases and conditions of patients with a novel coronavirus infection COVID-19, who died in infectious hospital." Perm Medical Journal 39, no. 5 (2022): 12–20. http://dx.doi.org/10.17816/pmj39512-20.

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Objective. To analyze the comorbid diseases and conditions in patients with a novel coronavirus infection COVID-19, who died in the infectious hospital. Materials and methods. Analysis of 1202 postmortem epicrises and protocols of pathologicoanatomic study of patients, who died in the infectious hospital of Smolensk on the basis of Clinical Hospital № 1 was carried out. Results. There prevailed elderly and old patients 81.5 %, most of them suffered from cardiovascular diseases (CVD), first of all ischemic heart disease 92 % and arterial hypertension 94.8 %. The most frequent risk f

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Hashiguchi, Kenichi, Ryota Kobayashi, Daichi Morioka, et al. "Prediction of Co-Occurrence of Lewy Body Disease with Alzheimer’s Disease." Journal of Alzheimer's Disease Reports 8, no. 1 (2024): 609–14. http://dx.doi.org/10.3233/adr-240019.

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Identifying the coexistence of Lewy body (LB) pathology with Alzheimer’s disease (AD) in clinical practice is important in the era of anti-amyloid-β antibody therapy. However, few studies have predicted the presence of comorbid LB pathology with AD using indicative biomarkers of dementia with Lewy bodies or by collecting detailed clinical symptoms. We report the clinical progression of a 67-year-old patient diagnosed with AD who developed rapid eye movement sleep disorder-like symptoms and transient visual hallucinations 10 years after AD onset and was considered to have comorbid LB pathology

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Voronko, Andrii, Olha Selіuk, Alla Buzhenko, et al. "Scoring of Professional Longevity of Patients with Arterial Hypertension of Military Personnel – the Participants of Modern Armed Conflicts." Family medicine. European practices, no. 4 (December 29, 2022): 11–17. http://dx.doi.org/10.30841/2786-720x.4.2022.274623.

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The prediction of ability for military service by the health of patients who are experienced (with war experience) military persons with arterial hypertension (AH) with existing comorbid pathology is an urgent issue of today and a component of national security. The objective: to analyze the of factors that influence on the prognosis of health service for the military service of patientsmilitary personnel with AH – the participants of anti-terrorist operation / operation of the united forces (ATO / OUF), taking into account the available comorbid pathology. Materials and methods. Medical card

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Voronko, Andrii, Olha Selіuk, Alla Buzhenko, et al. "Prolongation of Professional Longevity of Patients with Arterial Hypertension in Military Personnel Participating in Modern Armed Conflicts." Family Medicine. European Practices, no. 1 (February 28, 2023): 28–34. https://doi.org/10.30841/2786-720X.1.2023.277478.

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Abstract:

Arterial hypertension (AH) without proper treatment can lead to heart attack, stroke, kidney or heart failure, vision impairment and other complications. The determination of effective preventive measures to prolong siutability for military service based on the health status of experienced military persons with existing comorbid pathology is an urgent issue today and a component of national security. <strong>The objective:</strong> to analyze the effective measures that influence on the prolongation of the suitability for military service of military personnel with AH – the particip

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Naumov, A. V., T. V. Prokofieva, O. S. Polunina, L. V. Saroyants, and E. A. Polunina. "Proinflammatory cytokines in patients with acute myocardial infarction against the background of chronic obstructive pulmonary disease." Medical Herald of the South of Russia 11, no. 3 (2020): 40–47. http://dx.doi.org/10.21886/2219-8075-2020-11-3-40-47.

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Objective: To study and analyze serum levels of interleukins (IL): IL-1β, IL-2 and IL-6 in patients with myocardial infarction and chronic obstructive pulmonary disease.Materials and methods: In 85 people were examined: 28 patients with myocardial infarction, 37 patients with comorbid pathology (myocardial infarction and chronic obstructive pulmonary disease) and 20 somatically healthy volunteers as a control group. Determination of IL-1β, IL-2 and IL-6 levels was basing on enzyme immunoassay.Results: The median and inter-percentile range of IL-1β, IL-2 and IL-6 in the donors did not differ si

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