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Relevant bibliographies by topics / Comparative genomic hybridization / Dissertations / Theses

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Dissertations / Theses on the topic 'Comparative genomic hybridization'

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Published: 4 June 2021

Last updated: 20 February 2023

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1

Stanczak, Krzysztof M. "Detection of genomic deletions by single-nucleotide polymorphism array comparative genomic hybridization." Diss., Restricted to subscribing institutions, 2007. http://proquest.umi.com/pqdweb?did=1320950331&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Mantripragada, Kiran K. "Microarray-Based Comparative Genomic Hybridization in Neurofibromatoses and DiGeorge Syndrome." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5743.

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Burke, Natalie. "Genetic Imbalances in Endometriosis Detected by Oligonucleotide-Array Based Comparative Genomic Hybridization." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etd/1129.

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Endometriosis is one of the most common gynecological diseases as it is thought to affect up to 15% of the female population. Characterized by the growth and proliferation of endometrial tissue outside of the uterine cavity, it is a complex condition with varying degrees of severity and can affect multiple regions of the body with symptoms ranging from a total lack of symptoms to debilitating pain and infertility. The most accepted theory of how endometriosis initiates is that of retrograde menstruation; however, approximately 90% of women with unobstructed fallopian tubes are thought to have

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錢文偉 and Man-wai Gary Chien. "Cytogenetic analysis of head and neck cancer by comparative genomic hybridization." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31224209.

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Valentine, Erin L. "Microarray-based comparative genomic hybridization of three Adams Oliver syndrome families." Oklahoma City : [s.n.], 2009.

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6

Chien, Man-wai Gary. "Cytogenetic analysis of head and neck cancer by comparative genomic hybridization /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk:8888/cgi-bin/hkuto%5Ftoc%5Fpdf?B23440041.

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文詠賢 and Wing-yin Cornelia Man. "Genomic aberrations in lung cancer: a study with comparative genomic hybridization and analysis of loss ofheterozygosity." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31227697.

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Martin, Mallory N. "Microduplication 22q syndrome : investigation of intergenerational change using microarray-based comparative genomic hybridization /." Oklahoma City : [s.n.], 2009.

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9

Alshammari, Nawal. "Genetic biomarkers in uveal melanoma : an exploration using high-resolution array comparative genomic hybridization." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/16803/.

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Uveal melanomas (UM) are aggressive ocular tumours of adults that are typically characterized by chromosomal aberrations such as loss of 1p, 3, 6q, and gain 6p, and 8q. Of these monosomy 3 (M3) and 8q+ are powerful predictors of prognosis. The relationship of changes affecting chromosome 6 is however more ambivalent, having been linked to both good and poor prognosis, and yet both regions have not been well defined, which suggest the presence of one or more oncogenes in 6p and tumour suppressor gene in 6q. Therefore, different chromosome 6 alterations may have a variable impact on the prognosi

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Glen, McGillivary. "Comparative Genomic Analysis Between the Haemophilus influenzae biogroup aegyptius Brazilian Purpuric Fever Invasive Strain F3031 and the Haemophilus influenzae biogroup aegyptius Non-invasive Strain F1947." Miami University / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=miami1088607238.

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11

Chen, Beichen. "Identification of copy number variants associated with renal agenesis using array-based comparative genomic hybridization." Thesis, University of Iowa, 2010. https://ir.uiowa.edu/etd/655.

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Copy Number Variants (CNVs) are defined as DNA segments of 1kb or more in length and present in a variable number of copies in the human genome. It has been recently shown that many human genetic diseases including organ malformations are caused by CNVs in a patient's genome. However, the genetic and molecular basis for Renal Agenesis (RA), which is a medical condition whereby unilateral or bilateral fetal kidneys fail to develop, has not yet been extended to CNV studies. By using array-based Comparative Genomic Hybridization, we are analyzing DNA from patients who have RA in order to identify

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Benetkiewicz, Magdalena. "Development and Application of Human Chromosome 22 Genomic Microarray : Chromosome 22-Associated Disorders Analyzed by Array-Based Comparative Genomic Hybridization." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6272.

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Locke, Devin Paul. "SEGMENTAL DUPLICATIONS PROMOTE GENOMIC INSTABILITY IN HUMAN CHROMOSOME 15q11-q13." Case Western Reserve University School of Graduate Studies / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=case1088114861.

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Luk, Catherine Yuen Yee. "Molecular cytogenetic analysis of non-small cell lung carcinoma, by comparative genomic hybridization and spectral karyotyping." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0007/MQ45531.pdf.

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15

Maydan, Jason Stephen. "High-resolution mutation detection in Caenorhabditis elegans mutants and natural isolates using array comparative genomic hybridization." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/6683.

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An essential requirement of genetic research is the ability to identify mutations. Forward genetic screens begin by selecting for a phenotype and proceed to search for the causative mutation. Reverse genetics experiments first identify the mutation and then seek to derive the mutant phenotype, if any. Both approaches depend on efficient means of detecting mutations. This thesis describes the development of methods to facilitate the detection of mutations in the model organism, Caenorhabditis elegans, using array Comparative Genomic Hybridization (aCGH). Exon-centric oligonucleotide microarrays

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Castelli, Luciana Caricati Veiga. "Hibridação Genômica Comparativa em Endometriose." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/17/17135/tde-30052008-104355/.

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A endometriose é uma doença ginecológica benigna comum, mas agressiva, caracterizada pela presença de tecido endometrial ectópico. A teoria mais aceita para explicá-la é a teoria de Sampson, na qual o tecido endometrial descamado durante a menstruação sofre refluxo através das tubas uterinas, adere e se prolifera em sítios ectópicos da cavidade peritoneal. Por outro lado, apenas o refluxo tubário não é capaz de estabelecer a doença e vários estudos sugerem uma etiologia multidimensional incluindo fatores hereditários, hormonais e imunológicos. Várias metodologias têm sido propostas com o objet

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Buckley, Patrick. "Development and Application of Microarray-Based Comparative Genomic Hybridization : Analysis of Neurofibromatosis Type-2, Schwannomatosis and Related Tumors." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4786.

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Mahas, Ahmed Ibrahim. "Distinguishing Melanocytic Nevi From Melanoma by DNA Copy Number Changes: Array-Comparative Genomic Hybridization As a Research Tool." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1437782090.

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Alwohhaib, M. "Detection of somatic mutations in breast cancer and non-cancerous chromosomal disorders by the application of comparative genomic hybridization." Thesis, Swansea University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.635770.

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The aim of this study was to detect chromosomal imbalances in breast cancer and non-cancerous chromosomal disorders by comparative genomic hybridization (CGH). Initially, the technique was developed to be used on different types of samples. The samples used include DNA of patients suffering from different syndromes, frozen breast tumours tissue samples, and archival paraffin - embedded breast-tumour tissue sections. CGH application on the different syndromes have shown copy number changes in chromosome Y in two kabuki syndrome patients, imbalances at the X and Y chromosomes of the fragile X pa

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Potluri, Keerti. "Improving DNA quality using FFPE tissues for Array Comparative Genomic Hybridization to find Single Nucleotide Polymorphisms (SNPs) in Melanoma." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1438267267.

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Toujani, Saloua. "Du chromosome au gène par un criblage global des altérations génomiques dans la malignité pour isoler de nouvelles cibles thérapeutiques." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA11T027/document.

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Le cancer est désormais considéré comme une maladie génomique de la cellule. Les moyens d’étude de l’oncogénome étaient basés sur les différentes modalités du caryotype, peu résolutif. L’application des techniques de micromatrices d’oligonucléotides, notamment l’aCGH, a permis une avancée majeure dans la caractérisation des génomes des cancers.La première partie de notre travail a porté sur les lymphomes de Burkitt (LB), caractérisés par une translocation entre un gène d'immunoglobuline et MYC. L’étude portait sur 12 tumeurs primaires et 15 lignées cellulaires. L’aCGH (44K et 244K), concordait

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Gatto, Kaleb Pretto 1987. "Análise dos cromossomos sexuais de Pseudis tocantins (Anura, Hylidae)." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317686.

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Orientadores: Luciana Bolsoni Lourenço, Carmen Silvia Busin<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-23T12:08:20Z (GMT). No. of bitstreams: 1 Gatto_KalebPretto_M.pdf: 33988822 bytes, checksum: 7e3f3565dac9a540ea7c353f51068d4f (MD5) Previous issue date: 2013<br>Resumo: O resumo poderá ser visualizado no texto completo da tese digital<br>Abstract: The abstract is available with the full electronic document<br>Mestrado<br>Biologia Celular<br>Mestre em Biologia Celular e Estrutural

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Adhikari, Bishwo. "Genomic Analysis of Nematode-Environment Interaction." BYU ScholarsArchive, 2010. https://scholarsarchive.byu.edu/etd/2578.

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The natural environments of organisms present a multitude of biotic and abiotic challenges that require both short-term ecological and long-term evolutionary responses. Though most environmental response studies have focused on effects at the ecosystem, community and organismal levels, the ultimate controls of these responses are located in the genome of the organism. Soil nematodes are highly responsive to, and display a wide variety of responses to changing environmental conditions, making them ideal models for the study of organismal interactions with their environment. In an attempt to exa

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Catelani, Ana Lúcia Pereira Monteiro. "Variação no número de cópias de segmentos de DNA (CNV) em pacientes com surdez sindrômica." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-28062010-123759/.

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A perda auditiva é o defeito mais comum ao nascimento e cerca de 70 milhões de pessoas no mundo apresentam algum grau de perda auditiva. Além da alta incidência, as implicações da perda auditiva na linguagem, na cognição e no desenvolvimento emocional e social reforçam sua importância. No entanto, em grande parte dos pacientes, a causa da deficiência auditiva não é esclarecida. Nós usamos hibridação comparativa do genoma baseada em arrays (Array Comparative Genomic Hybridization aCGH) para investigar alterações no número de cópias de segmentos de DNA (Copy Number Variation CNV) em 31 indiví

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Yano, Cassia Fernanda. "Estudos evolutivos no gênero Triportheus (Characiformes, Triportheidae) com enfoque na diferenciação do sistema de cromossomos sexuais ZZ/ZW." Universidade Federal de São Carlos, 2016. https://repositorio.ufscar.br/handle/ufscar/8567.

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Submitted by Alison Vanceto (alison-vanceto@hotmail.com) on 2017-02-23T13:20:14Z No. of bitstreams: 1 TeseCFY.pdf: 5114033 bytes, checksum: 6922d93e7dda82cee55aa69273fa7013 (MD5)<br>Approved for entry into archive by Ronildo Prado (ronisp@ufscar.br) on 2017-03-14T19:51:58Z (GMT) No. of bitstreams: 1 TeseCFY.pdf: 5114033 bytes, checksum: 6922d93e7dda82cee55aa69273fa7013 (MD5)<br>Approved for entry into archive by Ronildo Prado (ronisp@ufscar.br) on 2017-03-14T19:52:08Z (GMT) No. of bitstreams: 1 TeseCFY.pdf: 5114033 bytes, checksum: 6922d93e7dda82cee55aa69273fa7013 (MD5)<br>Made available i

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Ashton, Kevin John. "Genetic Aberrations in Non-Melanoma Skin Cancer." Thesis, Griffith University, 2002. http://hdl.handle.net/10072/367012.

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Genetic changes are hallmarks of cancer development involving the activation and/or inactivation of oncogenes and tumour suppressor genes, respectively. In non-melanoma skin cancer (NMSC) development, the initiation of genetic mutations results from exposure to solar ultraviolet radiation. Non-melanoma skin cancers are comprised of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Several related cutaneous lesions also exist, of which solar keratoses (SK) are widely accepted as a precursor dysplasia to SCC development. The study of recurrent genetic changes present within NMSC and

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Mixão, Verónica de Pinho 1991. "Hybridization in Candida yeast pathogens." Doctoral thesis, Universitat Pompeu Fabra, 2020. http://hdl.handle.net/10803/670103.

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Candida species are among the most important fungal pathogens. Although Candida albicans is the most common cause of Candida infections, many other Candida species have emerged as pathogens. How pathogenicity is evolutionary acquired is unknown, but previous studies point to a role of hybridization in its development. This thesis studied the genomic features of Candida pathogens, with a special focus on hybrids and their evolution. Specifically, it asked the questions of how spread are hybrids among Candida species, and what are the processes that drive the evolution of their genomes. To this

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Michelland, Sylvie. "Déséquilibres génétiques dans les cancers bronchiques : une analyse par hybridation génomique comparative." Université Joseph Fourier (Grenoble), 1998. http://www.theses.fr/1998GRE10181.

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Le cancer du poumon est un probleme de sante publique majeur et il represente la premiere cause de mort par cancer chez l'homme dans le monde. Nous nous sommes interesses a l'analyse des desequilibres genetiques dans les tumeurs bronchiques dans le but d'etablir une cartographie precise des zones du genome associees a cette pathologie. Nous avons utilise la technique d'hybridation genomique comparative in situ (cgh) qui met en evidence de maniere rapide et globale l'ensemble des desequilibres genetiques presents dans une tumeur. Nous avons mis au point un protocole permettant d'obtenir des pre

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29

Giraud, Delphine. "Dynamique des éléments transposables et évolution du génome des spartines polyploïdes." Thesis, Rennes 1, 2019. http://www.theses.fr/2019REN1B057.

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Les conséquences de la spéciation divergente ou réticulée (par hybridation) ont été explorées au cours de la diversification des spartines depuis 6-10MA à travers l’analyse des séquences répétées, de leur expression et régulation. Nous avons montré une corrélation entre éléments transposables, tailles de génome, et relations phylogénétiques, tout en mettant en évidence une dynamique variable des catégories d’éléments transposables ou de séquences satellites selon les lignées, et l’ancienneté des évènements de spéciation. L’abondance des éléments transposables a été mise en relation avec leur n

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Williams, Stephen. "IDENTIFICATION OF LOCI CONTRIBUTING TO THE SMITH-MAGENIS SYNDROME-LIKE PHENOTYPE AND MOLECULAR EVALUATION OF THE RETINOIC ACID INDUCED 1 GENE." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/65.

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Smith-Magenis syndrome (SMS) is a multiple congenital abnormalities intellectual disability syndrome that results from a deletion of chromosome 17p11.2 or mutation of the retinoic acid inducted one gene (RAI1). SMS is characterized by a multitude of phenotypic features including craniofacial defects, short stature, obesity, intellectual disability, self-abusive behavior, sleep disturbance and behavioral abnormalities. Interestingly, although SMS is a clearly defined syndrome with a known molecular change at its foundation, ~40% of all candidate cases sent to the Elsea lab for evaluation do n

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Ashton, Kevin John, and K. Ashton@griffith edu au. "Genetic Aberrations in Non-Melanoma Skin Cancer." Griffith University. School of Health Science, 2002. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030818.122305.

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Genetic changes are hallmarks of cancer development involving the activation and/or inactivation of oncogenes and tumour suppressor genes, respectively. In non-melanoma skin cancer (NMSC) development, the initiation of genetic mutations results from exposure to solar ultraviolet radiation. Non-melanoma skin cancers are comprised of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Several related cutaneous lesions also exist, of which solar keratoses (SK) are widely accepted as a precursor dysplasia to SCC development. The study of recurrent genetic changes present within NMSC and

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32

Suzuki, Keli Tieko. "Investigação molecular por sequenciamento do gene CBP em portadores da síndrome de Rubinstein-Taybi." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-24052012-154642/.

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A Síndrome de Rubinstein-Taybi (RTSs) é uma doença rara de herança autossômica dominante, caracterizada por dismorfismos craniofaciais, polegares e háluces alargados, deficiência intelectual e de crescimento. RTSs tem sido associada com mutações no gene CREBBP (CBP) e mutações menos frequentes no gene EP300 que foram descritas em oito indivíduos. CBP e p300 possuem alta homologia e são extremamente importantes em várias vias de sinalização, principalmente como coativadores de transcrição e na acetilação das histonas. Nosso estudo baseou-se na análise de alterações moleculares por sequenciament

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Liu, Iris. "Comparative genome hybridization reveals widespread genome variation in pathogenic cryptococcus species." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/5646.

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Genome variability can influence the virulence of pathogenic microbes. The availability of genome sequences for strains of the AIDS-associated fungal pathogens Cryptococcus neoformans and C. gattii presented an opportunity to use Comparative Genome Hybridization (CGH) to examine genome variability between strains of different molecular subtypes and ploidy. CGH analysis of 15 strains revealed extensive genomic variation including regions of difference (deletions and amplifications) and chromosome copy number variability. Although no common genomic change was observed for these 15 strains, three

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Eulálio, Inês Mariana Cardoso. "Developmente of a CNVs detection method through qPCR." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22507.

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Mestrado em Biotecnologia<br>Os copy number variations (CNVs) consistem em segmentos de DNA de uma kilobase ou mais, que se encontram num número variável de cópias, em comparação com um genoma de referência. A deteção de CNVs é convencionalmente realizada através de técnicas de citogenética, como fluorescence in situ hybridization e array comparative genomic hybridization, ou com base em PCR, como multiplex ligation-dependent probe amplification, SNP arrays ou deep sequencing. Porém, a evolução da técnica de PCR quantitativo em tempo real (qPCR) permitiu que fosse, actualmente, considerada o m

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Berglund, Mattias. "Molecular Characterization of Diffuse Large B-cell Lymphoma and Aspects of Transformation." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4266.

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Serson, William Richard. "INCREASING RENEWABLE OIL CONTENT AND UTILITY." UKnowledge, 2017. http://uknowledge.uky.edu/pss_etds/89.

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Since the dawn of agriculture man has been genetically modifying crop plants to increase yield, quality and utility. In addition to selective breeding and hybridization we can utilize mutant populations and biotechnology to have greater control over crop plant modification than ever before. Increasing the production of plant oils such as soybean oil as a renewable resource for food and fuel is valuable. Successful breeding for higher oil levels in soybean, however, usually results in reduced protein, a second valuable seed component. We show that by manipulating a highly active acyl-CoA: diacy

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Kincaid, Smith Julien. "Modification des traits d'histoire de vie au cours de l’hybridation et analyse des mécanismes moléculaires sous- jacents chez les parasites plathelminthes du genre Schistosoma." Thesis, Perpignan, 2018. http://www.theses.fr/2018PERP0028/document.

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Les changements globaux ont en partie pour effet de modifier les aires de répartition géographique des espèces. Les interactions nouvelles entre espèces n’ayant jamais été en contact peuvent potentiellement mener à des cas atypiques de reproduction, notamment l’hybridation. Ce phénomène peut avoir des implications épidémiologiques fortes car il peut conduire à la genèse de pathogènes hybrides. La combinaison du matériel génétique d’espèces distinctes peut conférer de meilleures capacités à la progéniture (vigueur hybride ou hétérosis), pouvant à terme potentiellement mener à des changements ad

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Aguiar, Simone dos Santos. "Pesquisa da amplificação e/ou deleção genica atraves da tecnica de hibridização genomica comparativa (CGH) e da leção dos genes P53 e RB1 atraves da tecnica de hibridação in situ fluorescente (FISH) no tecido do tumor de crianças e adolescentes com ost." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312071.

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Orientador: Silvia Regina Brandalise<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-06T21:43:20Z (GMT). No. of bitstreams: 1 Aguiar_SimonedosSantos_D.pdf: 43958145 bytes, checksum: b9dafbbd99ad0e567b3c1f03a0c7b37e (MD5) Previous issue date: 2006<br>Resumo: Introdução Os osteossarcomas (OS) são tumores agressivos, primários de osso, com prognóstico reservado. As deleções dos genes supressores de tumor, RBl e P53, localizados nos cromossomos 13 e 17 respectivamente, são freqüentemente encontradas neste tipo de tumor

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Baumgartner, Adolf. "Comparative genomic hybridization (CGH) in genotoxicology." 2013. http://hdl.handle.net/10454/10121.

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No<br>In the past two decades comparative genomic hybridization (CGH) and array CGH have become crucial and indispensable tools in clinical diagnostics. Initially developed for the genome-wide screening of chromosomal imbalances in tumor cells, CGH as well as array CGH have also been employed in genotoxicology and most recently in toxicogenomics. The latter methodology allows a multi-endpoint analysis of how genes and proteins react to toxic agents revealing molecular mechanisms of toxicology. This chapter provides a background on the use of CGH and array CGH in the context of genotoxicology a

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Santos, André Ferreira. "Development of a Database for Array Comparative Genomic Hybridization." Master's thesis, 2015. http://hdl.handle.net/10316/30808.

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Dissertação de Mestrado Integrado em Engenharia Biomédica apresentada à Faculdade de Ciências e Tecnologia da Universidade de Coimbra.<br>A técnica de Microarray de Hibridização Genómica Comparativa (arrayCGH) permitiu um avanço significativo no diagnóstico de doenças de desenvolvimento incompreensíveis através da deteção de variações do número de cópia genómicas (CNVs) que antes eram indetetáveis por outros tipos de tecnologias citogenéticas. Através desta técnica são detetadas síndromes genéticas já identificadas mas também novos distúrbios e novas doenças genómicas causadas por CNVs.

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Chen, Hung-I. Harry, and 陳鴻毅. "Development of a Normalization Algorithm for Array Comparative Genomic Hybridization." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/86066366982034436673.

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碩士<br>國立臺灣大學<br>電機工程學研究所<br>95<br>Genomic instability is one of fundamental factors in tumorigenesis and tumor progression. Many studies have shown that copy-number abnormalities at the DNA level are important in the pathogenesis of cancer. Array Comparative Genomic Hybridization (array CGH), developed based on expression microarray technology, can reveal the chromosomal aberrations in segmental copies at a high-resolution. However, due to the nature of array CGH, many standard expression data processing tools, such as data normalization, often failed to yield satisfactory results. We demonstr

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Chen, Hung-I. Harry. "Development of a Normalization Algorithm for Array Comparative Genomic Hybridization." 2007. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-1007200716470300.

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LIN, YI CHAO, and 林宜昭. "Analysis of chromosomal aberration in pancreatic carcinoma by comparative genomic hybridization." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/49141080339263080109.

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碩士<br>長庚大學<br>基礎醫學研究所<br>93<br>The mortality of pancreatic cancer in male is the ninth leading cause of cancer death during year 2003 in Taiwan, and that in female ranks eighth. In order to develop the new diagnostic, therapeutic and preventive methods of the disease, we ought to define the progression of the tumorigenesis mechanism of the cancer. However, what we know about the genetic mechanism of the disease is not enough. Hruban et al. (2000) proposed the genetic progression model for pancreatic intraepithelial neoplasias. It involved a set of genetic variations. The complicated copy n

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Lin, Yu-Shu, and 林育澍. "An Integration of Statistical Methods for Array-based Comparative Genomic Hybridization." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/71870029541893742750.

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碩士<br>國立臺灣大學<br>農藝學研究所<br>94<br>The DNA microarray is widely used to investigate gene expression profiles of many thousands of genes simultaneously. And it has become a common tool for exploring various questions in many areas of biological and medical sciences. Specifically, array-based comparative genomic hybridization (Array CGH) is applied to screen alteration of DNA copy numbers genomewide. The main purpose of such application is to detect the altered DNA segments among genome sequences from a control (reference) treatment to a test treatment. Typically, efficient statistical tools are de

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Freitas, Marta Catarina Baptista. "Prenatal diagnosis: the clinical usefulness of Array Comparative Genomic Hybridization (aCGH)." Master's thesis, 2017. https://hdl.handle.net/10216/104446.

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Freitas, Marta Catarina Baptista. "Prenatal diagnosis: the clinical usefulness of Array Comparative Genomic Hybridization (aCGH)." Dissertação, 2017. https://hdl.handle.net/10216/104446.

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Lai, Jiunn-Jei, and 賴俊吉. "Study of Chromosomal Aberrations in Nasal Lymphoma By Comparative Genomic Hybridization Technique." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/19102033855476926703.

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碩士<br>國立陽明大學<br>遺傳學研究所<br>88<br>Nasal lymphoma (nasal and nasal type T/NK cell lymphoma) is the most aggressive kind of lymphoma. It was most often occurred in nose or facial midline. And it is highly associated with Epstein Barr Virus. The incidence of nasal lymphoma in Asian and Native American are much higher than that of Caucasian. There are about three forth cases occurred in male. Besides, the prognosis of nasal lymphoma was very poor, and there was highly rate of relapse. Because of these reasons, we are interest in analyzing how it happens. Here, we want to realize the cytogenetics of

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Chen, Ming-Chih, and 陳明志. "Investigation on the People’s Willingness to Using the array-Comparative Genomic Hybridization." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/80244000447158336128.

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碩士<br>育達商業科技大學<br>行銷與流通管理所<br>101<br>Taiwan has been a highly developed country, where low birth rate has become an increasingly apparent phenomenon. More and more people choose not to have children, or insist on the spirit that one child is just enough and only have one child. In the trend of late marriage and late childbirth, middle and advanced maternal age has been quite common. However, the risk of preterm birth or congenital disease also increases with the age of women at childbirth. According to medical statistics, 4 in 100 newborns have birth defects in Taiwan, and it is estimated that

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"Identification of genetic abnormalities in nasopharyngeal carcinoma by comparative genomic hybridization and interphrase cytogenetics." 1999. http://library.cuhk.edu.hk/record=b5889980.

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Fan Chung-sze.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1999.<br>Includes bibliographical references.<br>Abstracts in English and Chinese.<br>Acknowledgements --- p.i<br>Abstract --- p.ii<br>List of Tables --- p.vii<br>List of Figures --- p.viii<br>List of Abbreviations --- p.x<br>Table of Contents --- p.xi<br>Chapter Chapter 1 --- Introduction<br>Chapter 1.1 --- Nasopharyngeal Carcinoma --- p.1-1<br>Chapter 1.1.1 --- Histology of NPC --- p.1-1<br>Chapter 1.1.2 --- Etiological Factors --- p.1-2<br>Chapter 1.1.3 --- Genetic Changes in NPC --- p.1-5<br>Chapter 1.2 --- Back

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"Chromosomal aberrations in hepatocellular carcinoma: a study by comparative genomic hybridization and interphase cytogenetics." 2000. http://library.cuhk.edu.hk/record=b5890480.

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Lee Siu-wah.<br>Thesis submitted in: December 1999.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2000.<br>Includes bibliographical references (leaves [106]-116).<br>Abstracts in English and Chinese.<br>Abstract (in English) --- p.i<br>Abstract (in Chinese) --- p.iii<br>Acknowledgements --- p.v<br>Table of Contents --- p.vi<br>List of Figures --- p.ix<br>List of Tables --- p.x<br>Abbreviations --- p.xi<br>Chapter Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- Hepatocellular Carcinoma (HCC) --- p.2<br>Chapter 1.2 --- Etiology of Hepatocellular Carcinoma --- p.5<br>Chapt

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