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Journal articles on the topic 'Comparison of survival curves'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Klemera, Petr, and Stanislav Doubal. "Gompertz — A program for evaluation and comparison of survival curves." AGE 23, no. 3 (2000): 129–32. http://dx.doi.org/10.1007/s11357-000-0014-9.

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2

Nizeyimana, Ildephonse, Samuel Mwalili, and George Orwa. "New Test for the Comparison of Survival Curves to Detect Late Differences." Journal of Probability and Statistics 2023 (March 1, 2023): 1–10. http://dx.doi.org/10.1155/2023/9945446.

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Background. Survival analysis attracted the attention of different scientists from various domains such as engineering, health, and social sciences. It has been widely exploited in clinical trials when comparing different treatments looking at their survival probabilities. Kaplan–Meier curves plotted from the Kaplan–Meier estimates of survival probabilities are used to depict the general image for such situations. Methods. The weighted log-rank test has been dealt with by suggesting different weight functions which give specific strength in specific situations. In this work, we proposed a new

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Chiu, Vi Kien, and Adele Lerolle-Chiu. "Integrated survival analysis." Journal of Clinical Oncology 41, no. 16_suppl (2023): e14695-e14695. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e14695.

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e14695 Background: Clinical trial efficacy may be determined by the primary endpoint(s) of median progression free survival (mPFS) and/or median overall survival (mOS) from the Kaplan-Meier estimate, and secondary endpoints of overall response rate (ORR) and duration of response (DOR). In the treatment of metastatic cancers, single agent immunotherapy tends to have lower ORR and longer DOR in comparison to chemotherapy or targeted tyrosine kinase inhibitor therapy, which tends to have higher ORR and shorter DOR. This leads to intersecting or crossing Kaplan-Meier survival curves, which are har

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Araujo, Olinda Maria Rodrigues de, Maria Lúcia Ivo, Marcos Antonio Ferreira Júnior, Elenir Rose Jardim Cury Pontes, Ieda Maria Gonçalves Pacce Bispo, and Eveny Cristine Luna de Oliveira. "Survival and mortality among users and non-users of hydroxyurea with sickle cell disease." Revista Latino-Americana de Enfermagem 23, no. 1 (2015): 67–73. http://dx.doi.org/10.1590/0104-1169.3385.2526.

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OBJECTIVE: to estimate survival, mortality and cause of death among users or not of hydroxyurea with sickle cell disease.METHOD: cohort study with retrospective data collection, from 1980 to 2010 of patients receiving inpatient treatment in two Brazilian public hospitals. The survival probability was determined using the Kaplan-Meier estimator, survival calculations (SPSS version 10.0), comparison between survival curves, using the log rank method. The level of significance was p=0.05.RESULTS: of 63 patients, 87% had sickle cell anemia, with 39 using hydroxyurea, with a mean time of use of the

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Buyse, Marc, Tomasz Burzykowski, Mahesh Parmar, et al. "Using the Expected Survival to Explain Differences Between the Results of Randomized Trials: A Case in Advanced Ovarian Cancer." Journal of Clinical Oncology 21, no. 9 (2003): 1682–87. http://dx.doi.org/10.1200/jco.2003.04.088.

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Purpose: A meta-analysis of randomized trials in advanced ovarian cancer showed a longer survival with cyclophosphamide, doxorubicin, and cisplatin (CAP) than with cyclophosphamide and cisplatin (CP; P = .009). In contrast, the results of the large International Collaborative Ovarian Neoplasm Study (ICON2) showed no survival difference between CAP and carboplatin (P = .98). In this article, we show how these discrepant results can be reconciled through the estimation of expected survival curves. Materials and Methods: A proportional hazards model, fitted to the meta-analysis data, was used to

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Perry, R., M. Taylor, L. Lewis, A. Yellowlees, K. Fleetwood, and T. Barata. "Estimating Survival Data from Published Kaplan-Meier Curves: a Comparison of Methods." Value in Health 17, no. 7 (2014): A326. http://dx.doi.org/10.1016/j.jval.2014.08.588.

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7

Li, Huimin, Dong Han, Yawen Hou, Huilin Chen, and Zheng Chen. "Statistical Inference Methods for Two Crossing Survival Curves: A Comparison of Methods." PLOS ONE 10, no. 1 (2015): e0116774. http://dx.doi.org/10.1371/journal.pone.0116774.

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Aleman, Alicia, Daniel Pedrosa, Magdalena Irisarri, Rafael Alonso, Ana Perez Galán, and Regina Guzman. "PD66 Indirect Comparison Of Treatments For Metastatic Melanoma." International Journal of Technology Assessment in Health Care 34, S1 (2018): 154. http://dx.doi.org/10.1017/s0266462318003276.

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Introduction:Vemurafenib plus cobimetinib (VC) for the treatment of metastatic melanoma was requested to be included in the National Formulary in Uruguay. The standard of care for metastatic melanoma in Uruguay is dacarbazine. There is no published head-to-head trial assessing the effects of VC versus dacarbazine. The objective of this study was to perform an indirect comparison of the effects of dacarbazine, compared with VC, based on the results of trials that included both treatments versus the same comparator (vemurafenib alone).Methods:We searched Pubmed and The Cochrane Library for trial

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Ghali, William A. "Comparison of 2 Methods for Calculating Adjusted Survival Curves From Proportional Hazards Models." JAMA 286, no. 12 (2001): 1494. http://dx.doi.org/10.1001/jama.286.12.1494.

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Shilovsky, G. A. "CALCULATION OF AGING: ANALYSIS OF SURVIVAL CURVES IN NORMAL AND IN PATHOLOGY, FLUCTUATIONS IN MORTALITY DYNAMICS, CHARACTERISTICS OF LIFE SPAN DISTRIBUTION AND INDICATORS OF ITS VARIATION." Биохимия 89, no. 2 (2024): 373–80. http://dx.doi.org/10.31857/s0320972524020138maruu.

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The article describes the history of studies of survival data carried out at the Research Institute of Physico-Chemical Biology under the leadership of Academician V. P. Skulachev from 1970s until present, with special emphasis on the last decade. The use of accelerated failure time (AFT) model and analysis of coefficient of variation of lifespan (CVLS) in addition to the Gompertz methods of analysis, allows to assess survival curves for the presence of temporal scaling (i.e., manifestation of accelerated aging), without changing the shape of survival curve with the same coefficient of variati

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VIRTO, R., D. SANZ, I. ÁLVAREZ, S. CONDON, and J. RASO. "Comparison of the Chlorine Inactivation of Yersinia enterocolitica in Chlorine Demand and Demand-Free Systems." Journal of Food Protection 68, no. 9 (2005): 1816–22. http://dx.doi.org/10.4315/0362-028x-68.9.1816.

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Inactivation of Yersinia enterocolitica by chlorine (0.6 to 20 ppm) was investigated in distilled water and in tryptic soy broth (TSB, 0.015%) at different temperatures (4, 20, and 40°C). In distilled water, chlorine inactivation of Y. enterocolitica was enhanced by increasing the temperature from 4 to 20°C, and survival curves were described by a model that assumed first-order kinetics followed by tailing in which the microbial concentration remained constant. The presence of TSB increased chlorine resistance of Y. enterocolitica, and survival curves were concave downward. These survival curv

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12

Heuser, Aaron, Minh Huynh, and Joshua C. Chang. "Asymptotic convergence in distribution of the area bounded by prevalence-weighted Kaplan–Meier curves using empirical process modelling." Royal Society Open Science 5, no. 11 (2018): 180496. http://dx.doi.org/10.1098/rsos.180496.

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The Kaplan–Meier product-limit estimator is a simple and powerful tool in time to event analysis. An extension exists for populations stratified into cohorts where a population survival curve is generated by weighted averaging of cohort-level survival curves. For making population-level comparisons using this statistic, we analyse the statistics of the area between two such weighted survival curves. We derive the large sample behaviour of this statistic based on an empirical process of product-limit estimators. This estimator was used by an interdisciplinary National Institutes of Health–Socia

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Arboretti, Rosa, Roberto Fontana, Fortunato Pesarin, and Luigi Salmaso. "Nonparametric combination tests for comparing two survival curves with informative and non-informative censoring." Statistical Methods in Medical Research 27, no. 12 (2017): 3739–69. http://dx.doi.org/10.1177/0962280217710836.

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This paper looks at permutation methods used to deal with hypothesis testing within the survival analysis framework. In the literature, several attempts have been made to deal with the comparison of survival curves and, depending on the survival and hazard functions of two groups, they can be more or less efficient in detecting differences. Furthermore, in some situations, censoring can be informative in that it depends on treatment effect. Our proposal is based on the nonparametric combination approach and has proven to be very effective under different configurations of survival and hazard f

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Forman, Sandra, Bruce Thompson, and Genell Knatterud. "P39 Selection of appropriate controls for comparison of survival curves with time-dependent events." Controlled Clinical Trials 16, no. 3 (1995): 94S. http://dx.doi.org/10.1016/0197-2456(95)90519-b.

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15

Haybittle, John L. "Significance testing in the comparison of survival curves from clinical trials of cancer treatment." European Journal of Cancer and Clinical Oncology 22, no. 11 (1986): 1279–83. http://dx.doi.org/10.1016/0277-5379(86)90133-1.

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Yamaguchi, Dean J., Thomas C. Matthews, Marjan Mujib, et al. "Survival Comparison of Patients Undergoing Secondary Aortic Repair." Advances in Vascular Medicine 2015 (April 5, 2015): 1–5. http://dx.doi.org/10.1155/2015/395921.

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Introduction. Infrarenal abdominal aortic aneurysm (AAA) repair warrants lifelong surveillance. Secondary aortic intervention (SAI) outcomes may be affected by the therapeutic approach. We compared short- and long-term mortality in patients who underwent SAIs after initial aortic repair, either endovascular (EVAR) or open. Methods. Patients who underwent AAA repair between 1986 and 2010 were retrospectively identified in a vascular surgery database as well as those who underwent SAIs. All-cause mortality and Kaplan-Meier survival curves were calculated. Results. We identified 149 patients who

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17

Brković-Popović, I. "Effect of Mercury on the Survival of Daphnia Magna." Water Science and Technology 22, no. 5 (1990): 241–46. http://dx.doi.org/10.2166/wst.1990.0035.

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The median lethal time (LT) for each concentration of mercury was determined on the basis of mortality curves. Toxicity curves (i.e., the median life-span of Daphniamagna, LT 50, versus the concentration of mercury) for four tested conditions are shown. The experiments were carried out using two diluents of different total hardness (46 and 119 mg/l as CaCO3), at two temperatures (20°C and 25°C). A comparison of the LT 50s of the control organisms with the LT 50s of the test organisms at mercury concentrations of 0.0075 and 0.0050 mg. l-1 showed that the chemical characteristics and temperature

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Bertolet, Alejandro, and Alejandro Carabe. "Modelling Dose Effects from Space Irradiations: Combination of High-LET and Low-LET Radiations with a Modified Microdosimetric Kinetic Model." Life 10, no. 9 (2020): 161. http://dx.doi.org/10.3390/life10090161.

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The Microdosimetric Kinetic Model (MKM) to predict the effects of ionizing radiation on cell colonies is studied and reformulated for the case of high-linear energy transfer (LET) radiations with a low dose. When the number of radiation events happening in a subnuclear domain follows a Poisson distribution, the MKM predicts a linear-quadratic (LQ) survival curve. We show that when few events occur, as for high-LET radiations at doses lower than the mean specific energy imparted to the nucleus, zF,n, a Poisson distribution can no longer be assumed and an initial pure linear relationship between

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Maguire, Douglas A., and Christine C. Maguire. "Analyzing treatment effects on Douglas-fir seedling survival with an extreme value regression model." Canadian Journal of Forest Research 17, no. 12 (1987): 1627–30. http://dx.doi.org/10.1139/x87-250.

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First year survival patterns in a cohort of natural Douglas-fir (Pseudotsugamenziesii (Mirb.) Franco) seedlings were assessed with an extreme value regression model. Extreme value distributions were fit to the data, assuming equal scale parameters among treatments but allowing location parameters to vary. The regression approach using indicator variables facilitated statistical comparison of survival curves among several habitats and treatments.

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20

Ossato, Andrea, Lorenzo Gasperoni, Luna Del Bono, Andrea Messori, and Vera Damuzzo. "Efficacy of Immune Checkpoint Inhibitors vs. Tyrosine Kinase Inhibitors/Everolimus in Adjuvant Renal Cell Carcinoma: Indirect Comparison of Disease-Free Survival." Cancers 16, no. 3 (2024): 557. http://dx.doi.org/10.3390/cancers16030557.

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Background: The proven efficacy of mTOR inhibitors (mTORIs), tyrosine kinase inhibitors (TKIs) or immune checkpoint inhibitors (ICIs) in metastatic renal cell carcinoma (RCC) suggests that these agents should be investigated as adjuvant therapy with the aim of eliminating undetectable microscopic residual disease after curative resection. The aim of our study was to compare the efficacy of these treatments using an innovative method of reconstructing individual patient data. Methods: Nine phase III trials describing adjuvant RCC treatments were selected. The IPDfromKM method was used to recons

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Hendry, J. H. "Survival Curves for Normal-tissue Clonogens: A Comparison of Assessments Usingin Vitro, Transplantation, orin SituTechniques." International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 47, no. 1 (1985): 3–16. http://dx.doi.org/10.1080/09553008514550021.

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Shetty, Shreya J., Lokesh Bathla, Venkatesh Govindarajan, Peter Thomas, and Brian W. Loggie. "Comparison of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy with Mitomycin or Carboplatin for Diffuse Malignant Peritoneal Mesothelioma." American Surgeon 80, no. 4 (2014): 348–52. http://dx.doi.org/10.1177/000313481408000415.

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Diffuse malignant peritoneal mesothelioma is a rare, aggressive disease. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have improved outcomes where systemic chemotherapy has not succeeded. In this study, we compare outcomes of patients treated with mitomycin or carboplatin as perfusate. In this retrospective study, 47 procedures (CRS + HIPEC) were conducted on 44 patients between March 2003 and August 2010 with either mitomycin or carboplatin. χ2 and Student's t test were used for comparison of clinicopathological variables and Kaplan-Meier curves and log ra

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Kumar, Shrawan. "On the comparison of survival curves of two groups of chronic kidney disease patients based on progressively censored data." Journal of Renal Endocrinology 8 (January 1, 2022): e16062. http://dx.doi.org/10.34172/jre.2022.16062.

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Introduction: Chronic kidney disease (CKD) is the progressive loss of kidney function. Prevalence of every stage of CKD is rising over the period with increasing number of diabetic, hypertensive and elderly population. It is becoming a problem of epidemic proportions in India. Objectives: Comparison of the survival function of CKD patients with different disease stages criticality grouped on the basis of gender, diabetes and hypertension. Patients and Methods: The retrospective data of 117 patients suffering from CKD during the period March 2006 to October 2016 is used. In the present study, l

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Zadnik, Vesna, Tina Žagar, and Maja Primic Žakelj. "Cancer Patients’ Survival: Standard Calculation Methods And Some Considerations Regarding Their Interpretation." Slovenian Journal of Public Health 55, no. 2 (2016): 144–51. http://dx.doi.org/10.1515/sjph-2016-0012.

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Abstract Background Cancer patients’ survival is an extremely important but complex indicator for assessing regional or global inequalities in diagnosis practices and clinical management of cancer patients. The population-based cancer survival comparisons are available through international projects (i.e. CONCORD, EUROCARE, OECD Health Reports) and online systems (SEER, NORDCAN, SLORA). In our research we aimed to show that noticeable differences in cancer patients’ survival may not always reflect the real inequalities in cancer care, but can also appear due to variations in the applied method

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Bromley, Alexandria, and Jennifer Perry. "Survival of Probiotic Lactobacillus spp. During Kombucha Fermentation." Current Developments in Nutrition 6, Supplement_1 (2022): 507. http://dx.doi.org/10.1093/cdn/nzac077.010.

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Abstract Objectives This study will determine if specific probiotics inoculated into unfermented sweetened tea can survive kombucha fermentation in appreciable quantities. Methods Growth curves for six probiotic Lactobacillus spp. in MRS broth or sweetened black tea incubated at species-recommended temperature (30°C or 37°C) or 25°C were created. Inoculated (∼9 logCFU/mL) sweet tea was also fermented with kombucha SCOBYs (n = 3), until a pH of 3.0 was reached. Probiotic populations were documented throughout fermentation and storage and were compared to previously constructed growth curves. Mo

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Rogula, Basia, Greta Lozano-Ortega, and Karissa M. Johnston. "A Method for Reconstructing Individual Patient Data From Kaplan-Meier Survival Curves That Incorporate Marked Censoring Times." MDM Policy & Practice 7, no. 1 (2022): 238146832210776. http://dx.doi.org/10.1177/23814683221077643.

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Introduction. Access to individual patient data (IPD) can be advantageous when conducting cost-effectiveness analyses or indirect treatment comparisons. While exact times of censoring are often marked on published Kaplan-Meier (KM) curves, an algorithm for reconstructing IPD from such curves that allows for their incorporation is presently unavailable. Methods. An algorithm capable of incorporating marked censoring times was developed to reconstruct IPD from KM curves, taking as additional inputs the total patient count and coordinates of the drops in survival. The reliability of the algorithm

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Kusumoto, Tamon, Ryo Ogawara, Kazuyo Igawa, et al. "Scaling parameter of the lethal effect of mammalian cells based on radiation-induced OH radicals: effectiveness of direct action in radiation therapy." Journal of Radiation Research 62, no. 1 (2020): 86–93. http://dx.doi.org/10.1093/jrr/rraa111.

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ABSTRACT We have been studying the effectiveness of direct action, which induces clustered DNA damage leading to cell killing, relative to indirect action. Here a new criterion Direct Ation-Based Biological Effectiveness (DABBLE) is proposed to understand the contribution of direct action for cell killing induced by C ions. DABBLE is defined as the ratio of direct action to indirect action. To derive this ratio, we describe survival curves of mammalian cells as a function of the number of OH radicals produced 1 ps and 100 ns after irradiation, instead of the absorbed dose. By comparing values

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Teniola, Babalola Bayowa, Adeleke Raphael Ayantunji, Halid Omobolaji Yusuf, et al. "Statistical Powers of Some Tests for Checking Homogeneity of Survival Distributions with Disjointed Ends in the Presence of Censoring." International Journal of Analysis and Applications 20 (September 12, 2022): 46. http://dx.doi.org/10.28924/2291-8639-20-2022-46.

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This paper considered the comparison of some tests for assessing the overall homogeneity of Kaplan-Meier survival curves under low and high censoring rates when the curves are disjointed towards the end. The performances of these tests were measured by their statistical powers. Monte Carlo simulation study was conducted to evaluate and numerically compare the relative performances of Log-rank,Wilcoxon, Tarone-Ware, Peto-Peto, Modified Peto-Peto, the Fleming-Harrington (1,1), and the Babalola-Adeleke tests. The result obtained shows that the Babalola-Adeleke and Fleming-Harrington (1,1) tests h

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Ruijter, J. M. "Calculation of survival curves and statistical comparison of two censored populations: A computer program in BASIC." Computers and Biomedical Research 22, no. 1 (1989): 11–17. http://dx.doi.org/10.1016/0010-4809(89)90010-4.

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Bajpai, Basant K., Aidanas Preiksaitis, Saulius Vosylius, and Saulius Rocka. "Association Between the Cerebral Autoregulation Index (Pressure Reactivity), Patient’s Clinical Outcome, and Quality of ABP(t) and ICP(t) Signals for CA Monitoring." Medicina 56, no. 3 (2020): 143. http://dx.doi.org/10.3390/medicina56030143.

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Background and Objectives: The aim of this study was to explore the association between the cerebral autoregulation (CA) index, the pressure reactivity index (PRx), the patient’s clinical outcome, and the quality of arterial blood pressure (ABP(t)) and intracranial blood pressure (ICP(t)) signals by comparing two filtering methods to derive the PRx. Materials and Methods: Data from 60 traumatic brain injury (TBI) patients were collected. Moving averaging and FIR (Finite Impulse Response) filtering were performed on the ABP(t) and ICP(t) signals, and the PRx was estimated from both filtered dat

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Demir, I., and H. A. van de Venter. "Survival of watermelon (Citrullus lanatus (Thunb.) Matsum. and Nakai) seeds at 40°C prolonged by prior storage at 30°C." Seed Science Research 9, no. 3 (1999): 259–61. http://dx.doi.org/10.1017/s0960258599000264.

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AbstractSeeds of watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai var. Congo) were subjected to mild accelerated ageing treatments of 30 and 60 d at 30°C at a moisture content of 7.2%. In comparison to a cold-stored control, normal germination and viability were slightly (but not significantly) decreased by these treatments. Subsequent construction of survival curves during storage at 40°C, at seed moisture contents ranging from 10–18%, revealed that the prior 30°C ageing treatments prolonged survival under these conditions.

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Rael, Michael, Agnes Benedict, Jack Ishak, Sarah Cadarette, Marco Campioni, and Sumeet Panjabi. "Indirect Comparison to Assess the Relative Efficacy of Carfilzomib + Lenalidomide + Dexamethasone Versus Bortezomib + Thalidomide + Dexamethasone: A Matching Adjusted Indirect Comparison." Blood 126, no. 23 (2015): 5624. http://dx.doi.org/10.1182/blood.v126.23.5624.5624.

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Abstract Background: Several novel treatments have recently been approved for the treatment of relapsed multiple myeloma (RMM). In the absence of head-to-head comparisons between these novel treatments, clinicians and payers must rely on statistical indirect comparisons. The objective of this analysis is to derive measures of relative effectiveness for carfilzomib + lenalidomide + dexamethasone (KRd) against bortezomib + thalomide + dexamethasone (VTd) in patients with RMM who have been treated with at least one prior therapy and who had an autologous stem cell transplant (ASCT). Methods: A ma

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den Hollander, Jan G., Jenny D. Knudsen, Johan W. Mouton, et al. "Comparison of Pharmacodynamics of Azithromycin and Erythromycin In Vitro and In Vivo." Antimicrobial Agents and Chemotherapy 42, no. 2 (1998): 377–82. http://dx.doi.org/10.1128/aac.42.2.377.

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ABSTRACT In this study, we determined the efficacy of various dosing regimens for erythromycin and azithromycin against four pneumococci with different susceptibilities to penicillin in an in vitro pharmacokinetic model and in a mouse peritonitis model. The MIC was 0.03 μg/ml, and the 50% effective doses (determined after one dose) of both drugs were comparable for the four pneumococcal strains and were in the range of 1.83 to 6.22 mg/kg. Dosing experiments with mice, using regimens for azithromycin of one to eight doses/6 h, showed the one-dose regimen to give the best result; of the pharmaco

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Yu, Zihan, Rong Hu, and Jiaqing Chen. "A Study Investigating Interpretable Deep Learning Models for Predicting Mortality and Survival in Patients with Primary Thyroid Lymphomas." Applied Sciences 15, no. 9 (2025): 5146. https://doi.org/10.3390/app15095146.

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Primary thyroid lymphoma (PTL) is a rare malignancy, and this study aimed to develop a prognostic prediction model for PTL using deep learning algorithms while providing interpretable analyses. Machine learning models were employed for mortality risk prediction, with the SHAP framework introduced for feature interpretation, and a DeepSurv model was constructed for comparison with the Cox proportional hazards (Cox-PH) model. Model performance was evaluated using Harrell’s c-index, ROC curves, AUC, calibration curves, and decision curve analysis (DCA). Results revealed that age, ‘B’ symptoms, hi

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Wu, Qiuji, Juan Wang, Shaojie Li, et al. "Comparison of Definitive Radiotherapy-Based Treatment and Surgical-Based Treatment for Locally Advanced Head and Neck Soft Tissue Sarcoma." Journal of Clinical Medicine 12, no. 9 (2023): 3099. http://dx.doi.org/10.3390/jcm12093099.

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Background: Head and neck soft-tissue sarcomas are rare but aggressive malignancies. Definitive radiotherapy might be an alternative treatment choice in patients unfit for surgery with preservation of organ function and facial morphology. Whether definitive radiotherapy is comparable with surgery has not been fully demonstrated. In this study, we compared the prognosis of patients with radiotherapy-based treatment and with surgery-based treatment. Methods: From May 2014 to February 2021, patients with locally advanced head and neck soft-tissue sarcoma treated with either definitive radiotherap

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Hutson, Alan D. "A robust semi-parametric warping estimator of the survivor function with an application to two-group comparisons." Statistical Methods in Medical Research 27, no. 2 (2016): 384–97. http://dx.doi.org/10.1177/0962280216630342.

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In this note, we develop a new and novel semi-parametric estimator of the survival curve that is comparable to the product-limit estimator under very relaxed assumptions. The estimator is based on a beta parametrization that warps the empirical distribution of the observed censored and uncensored data. The parameters are obtained using a pseudo-maximum likelihood approach adjusting the survival curve accounting for the censored observations. In the univariate setting, the new estimator tends to better extend the range of the survival estimation given a high degree of censoring. However, the ke

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Porter, D. E., V. Prasad, L. Foster, G. F. Dall, R. Birch, and R. J. Grimer. "Survival in Malignant Peripheral Nerve Sheath Tumours: A Comparison between Sporadic and Neurofibromatosis Type 1-Associated Tumours." Sarcoma 2009 (2009): 1–5. http://dx.doi.org/10.1155/2009/756395.

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We studied 123 patients with malignant peripheral nerve sheath tumours (MPNSTs) between 1979 and 2002. However, 90 occurred sporadically whereas 33 were associated with neurofibromatosis type 1 (NF1). Survival was calculated using Kaplan-Meier survival curves and we used Cox's proportional hazards model to identify independent prognostic factors. A 5-year survival for 110 nonmetastatic patients was 54%; (33% NF1 and 63% sporadic ). Tumour stage and site were significant prognostic indicators after univariate analysis. After multivariate analysis, however, only NF1 () and tumour volume more tha

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Li, Shuo, Xiang-Yu Meng, Souraka Tapara Dramani Maman, Yong-Nong Xiao, and Sheng Li. "Lenalidomide and Low Dose Dexamethasone Plus Elotuzumab or Carfilzomib for Relapsed or Refractory Multiple Myeloma: A Comparison of Progression-Free Survival with Reconstructed Individual Participant Data." BioMed Research International 2018 (December 16, 2018): 1–6. http://dx.doi.org/10.1155/2018/9057823.

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Background. Refractory and relapsed multiple myeloma (RRMM) remains a clinical challenge. We compared the progression-free survival (PFS) of RRMM patients treated with lenalidomide and low dose dexamethasone plus elotuzumab or carfilzomib (ELD vs. CLD), using reconstructed individual patient data (IPD) based on two published trials reports. Methods. We extracted data of study-level characteristics from original trial reports. We evaluated the comparability between the two treatment groups in terms of baseline status. Digitization of PFS Kaplan-Meier curves, reconstruction of IPD data, and subs

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Peternelli, Luiz Alexandre, Flávia Sílvia Corrêa Tomaz, Diego Paiva Bernardes, Gilson Fernandes da Silva, and Fabricia Gonçalves Lacerda. "An alternative method for assessing the equivalence among treatments in survival analysis." Ciência Rural 43, no. 9 (2013): 1553–60. http://dx.doi.org/10.1590/s0103-84782013000900004.

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This work aims to evaluate the use of parametric models instead of a nonparametric procedure to adjust survival curves related to different treatments, and to verify the equivalence among treatments by the multivariate method of cluster analysis. The dataset used to validate the method was obtained from a laboratory experiment with cutting ants. Eight colonies of cutting ants were used, each one receiving different treatments. The exponential, Weibull, log-normal, and logistic models were adjusted for each treatment, along with the usual Kaplan-Meier adjustment. The logistic model used was the

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Karrison, Theodore, and Masha Kocherginsky. "Restricted mean survival time: Does covariate adjustment improve precision in randomized clinical trials?" Clinical Trials 15, no. 2 (2018): 178–88. http://dx.doi.org/10.1177/1740774518759281.

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Background: Restricted mean survival time is a measure of average survival time up to a specified time point. There has been an increased interest in using restricted mean survival time to compare treatment arms in randomized clinical trials because such comparisons do not rely on proportional hazards or other assumptions about the nature of the relationship between survival curves. Methods: This article addresses the question of whether covariate adjustment in randomized clinical trials that compare restricted mean survival times improves precision of the estimated treatment effect (differenc

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GEHRIG, P. A., D. E. MORRIS, and L. VAN LE. "Uterine serous carcinoma: a comparison of therapy for advanced-stage disease." International Journal of Gynecologic Cancer 14, no. 3 (2004): 515–20. http://dx.doi.org/10.1136/ijgc-00009577-200405000-00014.

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Management of advanced-stage uterine serous carcinoma (USC) is uncertain, and postsurgical therapeutic options swing between radiation and chemotherapy. The aim of this study is to evaluate the utility of radiotherapy compared to platinum-based chemotherapy in women with advanced-stage USC. We retrospectively identified cases of USC at our institution. Survival distributions were calculated by the Kaplan–Meier method. Two-tailedt-tests were used to compare time to progression and time to death. We identified 24 women diagnosed with either stage III or IV USC. Time to progression for women rece

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Cope, Shannon, Sam T. Keeping, Rachel Goldgrub, et al. "Indirect comparison of nivolumab ± ipilimumab (CheckMate 032) versus other treatments for recurrent small-cell lung cancer." Journal of Comparative Effectiveness Research 8, no. 10 (2019): 733–51. http://dx.doi.org/10.2217/cer-2018-0130.

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Aim: To estimate the comparative efficacy of nivolumab ± ipilimumab versus alternative treatments for small-cell lung cancer after at least one prior line of chemotherapy. Materials & m ethods: A systematic literature review identified six randomized controlled trials (RCTs) that could be connected in a network. The Kaplan–Meier survival curves from these RCTs were synthesized using network meta-analysis models. Aggregate-level matching was used to connect CheckMate 032 to the RCTs. Results: CheckMate 032 was connected to the network by Amrubicin Clinical Trial-1. Nivolumab ± ipilimumab ha

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Liu, Xiao-Hong, Gong Chen, De-Dong Cao, et al. "Comparison of clinical features of patients with or without severe gastrointestinal complications in aggressive gastrointestinal lymphomas." World Journal of Gastrointestinal Oncology 16, no. 11 (2024): 4409–23. http://dx.doi.org/10.4251/wjgo.v16.i11.4409.

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BACKGROUND Aggressive primary gastrointestinal non-Hodgkin lymphoma (PGINHL) is an uncommon and heterogeneous group of lymphoid malignancies, that differs from indolent lymphoma and has a high incidence of severe gastrointestinal complications (GICs). AIM To investigate and compare the clinicopathological characteristics, treatments and outcomes in the GICs and No-GICs group with aggressive PGINHL. METHODS This retrospective analysis was performed on aggressive PGINHL patients between January 2013 and December 2021 at our hospital. The independent influence factors of GICs were obtained by uni

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Allan, John N., Christopher P. Fox, Grzegorz S. Nowakowski, et al. "Indirect Comparisons of the Efficacy of Epcoritamab Vs Glofitamab in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)." Blood 144, Supplement 1 (2024): 2349. https://doi.org/10.1182/blood-2024-203994.

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Background: Epcoritamab (epcor) is a first-in-class CD3xCD20 bispecific antibody (bsAb) approved for the treatment of 3L+ LBCL and follicular lymphoma. In the single-arm, phase 1/2, EPCORE NHL-1 trial (NCT03625037), epcor given until disease progression or unacceptable toxicity, demonstrated deep and durable responses, a median overall survival (OS) of 18.5 months, and a manageable safety profile in R/R LBCL. A second CD3xCD20 bsAb given as fixed-treatment duration, glofitamab (glofit), also demonstrated durable responses, conferring a median OS of 11.5 months in the pivotal study. Understandi

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FUJIKAWA, HIROSHI, SATOSHI MOROZUMI, GLEN H. SMERAGE, and ARTHUR A. TEIXEIRA. "Comparison of Capillary and Test Tube Procedures for Analysis of Thermal Inactivation Kinetics of Mold Spores." Journal of Food Protection 63, no. 10 (2000): 1404–9. http://dx.doi.org/10.4315/0362-028x-63.10.1404.

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Characteristics of capillary and test tube procedures for thermal inactivation kinetic analysis of microbial cells were studied for mold spores. During heating, capillaries were submerged in a water bath and test tubes were held with their caps positioned above the level of the heating medium. Thermal inactivation curves of Aspergillus niger spores in capillaries at around 60°C consisted of a shoulder and a fast linear decline, whereas curves in test tubes consisted of a shoulder, a fast linear decline, and a horizontal tail. There were no significant differences in values of the rate and the

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Pruitt, Ronald S. "Small sample comparison of six bivariate survival curve estimators1." Journal of Statistical Computation and Simulation 45, no. 3-4 (1993): 147–67. http://dx.doi.org/10.1080/00949659308811478.

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Parrotta, Jacqueline N., Marie Kristine Panganiban, Paul E. Feustel, Alyse Dicenzo, and John W. Simon. "Long-term Cosmetic Alignment Following Surgery for Esotropia Versus Exotropia in Childhood: A Comparison Using Survival Curves." Journal of Pediatric Ophthalmology & Strabismus 52, no. 6 (2015): 339–42. http://dx.doi.org/10.3928/01913913-20150924-11.

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Tunthanathip, Thara, and Thakul Oearsakul. "Comparison of predicted survival curves and personalized prognosis among cox regression and machine learning approaches in glioblastoma." Journal of Medical Artificial Intelligence 6 (July 2023): 10. http://dx.doi.org/10.21037/jmai-22-98.

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CLAUS, J. J., G. J. M. WALSTRA, P. M. BOSSUYT, S. TEUNISSE, and W. A. VAN GOOL. "A simple test of copying ability and sex define survival in patients with early Alzheimer's disease." Psychological Medicine 29, no. 2 (1999): 485–89. http://dx.doi.org/10.1017/s0033291798007375.

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Background. We studied whether heterogeneous profiles of cognitive function are relevant to survival in patients with early Alzheimer's disease.Methods. CAMCOG subscales of cognitive function were used as predictors of survival, together with gender in 157 consecutively referred patients with early Alzheimer's disease. Statistical analysis was performed with Cox proportional hazards analysis and Kaplan–Meier survival curves. Survival rates were compared with those in the general population.Results. Eighty patients (51%) died during the follow-up that extended to 5·7 years, with a median surviv

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Vilkov, V. G., S. A. Shalnova, A. V. Kapustina, G. A. Muromtseva, and O. M. Drapkina. "Comparison of thirty-year survival in the populations of Russia and the United States of America." Cardiovascular Therapy and Prevention 22, no. 5 (2023): 3556. http://dx.doi.org/10.15829/1728-8800-2023-3556.

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Aim. To compare survival at a 30-year follow-up in the populations of Russia and USA.Material and methods. From the Russian studies of 1975-1982, 14728 men and 6140 women aged 18-71 years were included, with follow-up until 2017 (501016 person-years of follow-up). In addition, 2265 men and 2345 women aged 18-71 years from the US population (The Third National Health and Nutrition Examination Survey) were compared with survey data in 1988-1994, with mortality follow-up until 2019 (115523 person-years of follow-up). Kaplan-Meier curves were created in groups of men and women aged 18-29, 30-39, 4

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