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1

Law, S. K. A. Complement. 2nd ed. IRL Press at Oxford University Press, 1995.

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2

Müller-Eberhard, Hans J., and Peter A. Miescher, eds. Complement. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-82416-6.

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3

Reid, Kenneth B. M., 1943-, ed. Complement. IRL Press, 1988.

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4

Frank, Michael M. Complement. Upjohn, 1985.

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5

1927-, Müller-Eberhard Hans J., and Miescher Peter A, eds. Complement. Springer-Verlag, 1985.

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6

Lambris, John D., V. Michael Holers, and Daniel Ricklin, eds. Complement Therapeutics. Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-4118-2.

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7

1937-, Cruse Julius M., and Lewis R. E. 1947-, eds. Complement today. Karger, 1993.

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8

Roumenina, Lubka T., ed. The Complement System. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1016-9.

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9

Gadjeva, Mihaela, ed. The Complement System. Humana Press, 2014. http://dx.doi.org/10.1007/978-1-62703-724-2.

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10

Rother, Klaus, Gerd O. Till, and G. Maria Hänsch, eds. The Complement System. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-58753-5.

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11

Loos, Michael, ed. Bacteria and Complement. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-45604-6.

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12

Szebeni, Janos, ed. The Complement System. Springer US, 2004. http://dx.doi.org/10.1007/b110959.

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13

Rother, Klaus, and Gerd O. Till, eds. The Complement System. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-97038-2.

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14

1926-, Rother K., and Till Gerd O. 1939-, eds. The Complement system. Springer-Verlag, 1988.

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15

1926-, Rother K., Till Gerd O. 1939-, and Hänsch G. M. 1950-, eds. The complement system. 2nd ed. Springer, 1998.

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16

Michael, Loos, ed. Bacteria and complement. Springer-Verlag, 1985.

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17

1954-, Szebeni Janos, ed. The complement system: Novel roles in health and disease. Kluwer Academic Publishers, 2004.

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18

D, Ross Gordon, ed. Immunobiology of the complement system: An introduction for research and clinical medicine. Academic Press, 1986.

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19

Morgan, B. Paul. Complement Methods and Protocols. Humana Press, 2000. http://dx.doi.org/10.1385/159259056x.

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20

Santos, Ana Lúcia, and Anabela Gonçalves, eds. Complement Clauses in Portuguese. John Benjamins Publishing Company, 2018. http://dx.doi.org/10.1075/ihll.17.

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21

Zipfel, Peter F., ed. Complement and Kidney Disease. Birkhäuser-Verlag, 2006. http://dx.doi.org/10.1007/3-7643-7428-4.

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22

Lambris, John D., ed. Current Topics in Complement. Springer US, 2006. http://dx.doi.org/10.1007/0-387-34134-x.

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23

W, Dodds Alister, and Sim Robert B, eds. Complement: A practical approach. IRL Press at Oxford University Press, 1997.

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24

J, Lachmann P., ed. The Biology of complement. Springer International, 1994.

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25

F, Zipfel Peter, ed. Complement and kidney disease. Birkhäuser, 2005.

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26

Paul, Morgan B., ed. Complement methods and protocols. Humana Press, 2000.

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27

B, Sim R., ed. Activators and inhibitors of complement. Kluwer Academic Publishers, 1993.

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28

Keith, Whaley, ed. Methods in complement for clinical immunologists. Churchill Livingstone, 1985.

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29

Whaley, K., M. Loos, and J. M. Weiler, eds. Complement in Health and Disease. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2214-6.

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30

Lambris, John D., ed. The Third Component of Complement. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74977-3.

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31

Sim, Robert B., ed. Activators and Inhibitors of Complement. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2757-8.

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32

Lambris, John D., ed. Current Topics in Complement II. Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-78952-1.

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33

Müller-Eberhard, H. J., and P. A. Miescher. Complement. Springer London, Limited, 2012.

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34

Pickering, Matthew C., and Jyoti Bakshi. Complement. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0064.

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In this chapter we summarize clinically important aspects of complement biology. This information is used to present a comprehensive overview of complement deficiency states and provide a logical basis for understanding complement assays in clinical practice. Hypocomplementaemic urticarial vasculitis syndrome, a condition associated with anti-C1q antibodies and complement consumption, is discussed. We summarize the use of eculizumab, a monoclonal antibody that targets and inhibits complement C5, in the treatment of haemolysis in paroxysmal nocturnal haemoglobinuria and atypical haemolytic urae
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35

Pickering, Matthew C., and Jyoti Bakshi. Complement. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642489.003.0064_update_001.

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In this chapter we summarize clinically important aspects of complement biology. This information is used to present a comprehensive overview of complement deficiency states and provide a logical basis for understanding complement assays in clinical practice. Hypocomplementaemic urticarial vasculitis syndrome, a condition associated with anti-C1q antibodies and complement consumption, is discussed. We summarize the use of eculizumab, a monoclonal antibody that targets and inhibits complement C5, in the treatment of haemolysis in paroxysmal nocturnal haemoglobinuria and atypical haemolytic urae
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36

Meyer, Harriet S. Complement. Oxford University Press, 2009. http://dx.doi.org/10.1093/jama/9780195176339.022.491.

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37

Staff, CIBA Foundation Symposium, and G. E. Wolstenholme. Complement. Wiley & Sons, Limited, John, 2008.

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38

Wolstenholme, G. E. W., and Julie Knight. Complement. Wiley & Sons, Incorporated, John, 2009.

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39

Muller-Eberhard, H., and P. Miescher. Complement. Springer Berlin / Heidelberg, 1985.

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40

Muller-Eberhard, H. J. Complement. Island Press, 1985.

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41

Lambris, John D., Daniel Ricklin, and V. Michael Holers. Complement Therapeutics. Springer London, Limited, 2012.

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42

Bhole, Malini. Complement deficiencies. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0299.

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The complement system comprises a group of heat-labile proteins which form part of the innate immune system. The main physiological functions of the complement system include defence against pyogenic bacterial infections, clearance of immune complexes and products of inflammatory damage, and acting as a bridge between the innate and adaptive immune system. The complement system is regulated by various complement inhibitors (regulatory proteins) that are present in both the classical pathway and the alternate pathway and which regulate and prevent spontaneous activation of the complement system
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43

Chromosome Complement. Springer London, Limited, 2012.

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44

Rother, Klaus, and Gerd O. Till. Complement System. Springer London, Limited, 2012.

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45

Barnum, Scott R., and Theresa N. Schein. Complement FactsBook. Elsevier Science & Technology Books, 2017.

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46

Barnum, Scott R. Complement FactsBook. Elsevier Science & Technology Books, 1999.

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47

Barnum, Scott, and Theresa Scheing. Complement FactsBook. Elsevier Science & Technology Books, 2017.

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48

Lambris, John D., Daniel Ricklin, and V. Michael Holers. Complement Therapeutics. Springer, 2016.

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49

Wilson, Tracy. Coffee Complement. Beautiful Publications LLC, 2021.

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50

Rother, K., Gerd O. Till, and Gertrud M. Hänsch. Complement System. Springer London, Limited, 2012.

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