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Journal articles on the topic 'Complex Fibroadenoma'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Ankita, Shiksha, and Kumar Patel Pankaj. "Study of Histopathological Changes in Fibroadenoma of Breast." International Journal of Pharmaceutical and Clinical Research 14, no. 8 (2022): 379–84. https://doi.org/10.5281/zenodo.13356410.

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<strong>Background: </strong>Fibroadenoma represents a long-term risk for breast carcinomas especially in women with complex fibroadenomas, ductal hyperplasia, older women, or a family history of breast carcinoma. <strong>Material and Methods:</strong> This prospective study was done in Department of Pathology, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar from September 2021 to July 2022. Total 123 cases of fibroadenoma and further histopathological examination were done. Formalin fixed excisional breast biopsies of patients, with histopathological diagnosis of f

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2

Brouwer de Koning, I. M., H. C. van Heusden, S. J. J. Mol, M. L. Rots, W. A. Draaisma, and K. Bosscha. "A rapidly growing fibroadenoma in a pregnant woman: A case report." Breast Disease 42, no. 1 (2023): 325–30. http://dx.doi.org/10.3233/bd-230030.

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BACKGROUND: Fibroadenomas are the most common benign breast lesions in women. They present as a unilateral mass and can rapidly enlarge in size through hormonal changes. Fibroadenomas could be classified as small or giant, and as simple or complex. They are classified as ‘giant’ when the size exceeds 5 cm and/or weight 500 gram; and as ‘complex’ if one of the following characteristics is present: cysts with a size >3 mm, epithelial calcifications, sclerosing adenosis and papillary apocrine metaplasia. Giant fibroadenomas can cause compression of surrounding breast tissue or breast asymmetry

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3

Pavithra D, Harini R, Hemalatha A, et al. "Pathophysiological and epidemiological aspects of fibroadenoma of the breast: A review." World Journal of Biology Pharmacy and Health Sciences 15, no. 1 (2023): 049–54. http://dx.doi.org/10.30574/wjbphs.2023.15.1.0297.

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A fibroadenoma is a solid, not fluid-filled, unilateral, benign (non-cancerous), breast tumour. It is painless. Fibroadenoma the terms "Fibro" and "Adenoma" refer to the glandular structure in epithelial tissue, respectively. In most cases, they appear as a straightforward, moveable, painless, smooth, and well-defined lump. They could be found in one breast or both. fibroadenoma is most frequently detected in women between the ages of 14 and 35. The lump may gradually grow without any accompanying pain, nipple changes, or skin changes, however the menstrual cycle may cause variations in size.

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Pavithra, D., R. Harini, A. Hemalatha, et al. "Pathophysiological and epidemiological aspects of fibroadenoma of the breast: A review." World Journal of Biology Pharmacy and Health Sciences 15, no. 1 (2023): 049–54. https://doi.org/10.5281/zenodo.8327686.

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A fibroadenoma is a solid, not fluid-filled, unilateral, benign (non-cancerous), breast tumour. It is painless. Fibroadenoma the terms "Fibro" and "Adenoma" refer to the glandular structure in epithelial tissue, respectively. In most cases, they appear as a straightforward, moveable, painless, smooth, and well-defined lump. They could be found in one breast or both. fibroadenoma is most frequently detected in women between the ages of 14 and 35. The lump may gradually grow without any accompanying pain, nipple changes, or skin changes, however the menstrual cycle may cause

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5

Hota, Subhransu Kumar, Ranjana Giri, Hardik Kabra, Devika Chauhan, Prita Pradhan, and Pran Singh Pujari. "Complex fibroadenoma with focal ossification- an enigmatic finding in a less common tumor." International Surgery Journal 8, no. 5 (2021): 1650. http://dx.doi.org/10.18203/2349-2902.isj20211851.

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Breast lumps have diverse causes including benign as well as malignant lesions. Fibroadenoma (FA) is a common cause of breast lump. Complex fibroadenomas, a particular subtype, pose diagnostic dilemmas due to confusing the radiological findings and hold higher incidence of transformation to malignancy. A 49 year old female presented with a painless lump in right breast for 2 years which appeared calcified on radiology. Excision biopsy was performed which grossly revealed an encapsulated grey-white firm to hard with cystic areas. Microscopically the sections showed a well encapsulated fibroepit

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Jagtap, Sunil Vitthalrao, Swati Sunil Jagtap, Nidhi Rajubhai Goswami, and Neha Babasaheb Desai. "Juvenile fibroadenoma of the breast." IP Journal of Diagnostic Pathology and Oncology 7, no. 3 (2022): 183–86. http://dx.doi.org/10.18231/j.jdpo.2022.043.

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Juvenile fibroadenoma is a rare variant of fibroadenoma and is characterized by rapidly enlarging, painless, and unilateral masses. We presents a case of juvenile fibroadenoma of the breast in a 14 year old girl, presented with rapidly growing mass in the right breast of four months duration. On local examination a solitary, firm, mobile, unilateral, non-tender mass was felt in the upper and lower outer quadrant of the right breast, measuring 6.5 x 4.1 x 3.5cm. The overlying skin was normal. There was no axillary lymphadenopathy. The sonomammography of the right breast showed a single, oval, h

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7

Mulia, I. Gusti Bagus Lulut Premana, I. G. A. Sri Mahendra Dewi, and I. Wayan Juli Sumadi. "KARAKTERISTIK KLINIKOPATOLOGI PASIEN FIBROADENOMA MAMMAE DI RSUP SANGLAH DENPASAR TAHUN 2017-2018." E-Jurnal Medika Udayana 10, no. 4 (2021): 75. http://dx.doi.org/10.24843/mu.2021.v10.i4.p12.

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ABSTRAK Fibroadenoma mammae (FAM) yaitu tumor jinakGpadaXpayudaraGyangXberbatasGjelas danXberbentukGbenjolanXyangGdapatXdigerakkan. Penyebab fibroadenomaXyaitu adanya pathogenesis yang berhubungan dengan hipersensitivitas jaringan payudara local terhadap estrogen, factor makanan dan factor riwayat keluarga atau keturunan. Penelitian ini bertujuan untuk mengetahui gambaran karakteristik klinikopatologi pasien FAM di RSUP Sanglah Denpasar tahun 2017 – 2018. Penelitian ini merupakan penelitian deskriptif dengan metodeGpenelitian potong lintang. Sebanyak 94 sampel diambil dengan teknik total

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8

Ohashi, Ryuji, Miyuki Matsubara, Yasuhiko Watarai, et al. "Cytological features of complex type fibroadenoma in comparison with non-complex type fibroadenoma." Breast Cancer 23, no. 5 (2015): 724–31. http://dx.doi.org/10.1007/s12282-015-0632-9.

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9

Gogoi, Geetanjali, and Diganta Borgohain. "Complex fibroadenoma – A case report." International Journal of Biomedical Research 6, no. 8 (2015): 585. http://dx.doi.org/10.7439/ijbr.v6i8.2328.

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10

P, Sneha, and Kavitha Yevoor. "Study of Histopathological Changes in Fibroadenoma of the Breast." Annals of Pathology and Laboratory Medicine 10, no. 2 (2023): A13–18. http://dx.doi.org/10.21276/apalm.3194.

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Background: Fibroadenoma of the breast is a relatively frequently occurring tumor. Although often considered a benign tumour, several reports describe a higher risk of subsequent breast carcinoma in patients diagnosed with fibroadenoma. Increased risk depends on presence of complex changes within fibroadenoma, presence of hyperplasia and positive family history for breast cancer. Aims and Objectives: Our main aim was to study the histological variations within the fibroadenoma of the breast and also to identify those lesions with the possible risk of malignancy. Methods: Descriptiv

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Karasjov, Vladimir Ye, V. T. Dolgikh, and O. V. Leonov. "Treatment of fertile age patients with benign breast tumors." Russian Journal of Oncology 20, no. 3 (2015): 12–16. http://dx.doi.org/10.17816/onco40148.

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The article presents the results of the treatment of 85 fertile age women with breast fibroadenomas. They were operated either by partial mastectomy or by vacuum aspiration removal of fibroadenomas with En-Cor apparatus. The study evaluated therapeutic effect on the hormonal background of the women with breast fibroadenomas achieved by monophase microdose complex oral contraceptives (ethinyl estradiol at the dose of 20 pg) or by vacuum aspiration. The use of En-Cor apparatus was effective not only in total fibroadenoma removal, but also in excellent cosmetic results, reduction of the operation

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Ciurea, Anca Ileana, Hanelore Argentina Herţa, Cătălin George Iacoban, Bogdan Fetica, Liliana Rogojan, and Cristiana Augusta Ciortea. "Fibroadenomas and breast carcinoma: a possible answer to a frequently asked question. A pictorial essay." Medical Ultrasonography 20, no. 3 (2018): 385. http://dx.doi.org/10.11152/mu-1408.

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Fibroadenomas (FAs) are the most frequently encountered benign breast lesions in young women and due to the age of the patients, they are usually diagnosed by ultrasound. Although they rarely undergo malignant transformation, the patients remain concerned about the possibility of malignant transformation. The aim of this pictorial essay is to illustrate the appearance of classic and complex fibroadenomas, to discuss the risk factors and to highlight the imaging characteristics that raise the suspicion of malignant transformation. In other words, we try to answer, according to our experience an

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13

Balmiki, Pradeep, and Kamlesh Mourya. "Fibroadenoma of ectopic breast tissue in chest wall: a rare case report and review of the literature." International Surgery Journal 6, no. 9 (2019): 3389. http://dx.doi.org/10.18203/2349-2902.isj20194083.

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Fibroadenoma of ectopic breast tissue is a rare disease. Ectopuc breast tissues are found along milk line. Malignancy is more common than fibroadenoma in ectopic breast tissue. Ectopic breast tissue can be present with nipple or without nipple areola complex. Here we report a case of 20 years old patient having fibroadenoma of ectopic breast tissue in anterior chest wall without nipple areola complex. Patient underwent excision and biopsy. Histopathology confirmed it as fibroadenoma of the ectopic breast tissue. This case has been reported for its rarity and to reemphasise the importance of sc

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14

Phulware, RaviH, Samikshya Thapa, Arvind Kumar, and Sanjeev Kishore. "Cytomorphological features of complex fibroadenoma breast." Journal of Cytology 40, no. 4 (2023): 220. http://dx.doi.org/10.4103/joc.joc_58_23.

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15

Al-Darwish, Abdullah S., Hisham AlKhalidi, Hammad Akram, and Nuha A. Alsaleh. "Myxoid Fibroadenoma of the Breast: A Rare Histological Variant Case Report and Literature Review." Dr. Sulaiman Al Habib Medical Journal 6, no. 1 (2024): 27–29. http://dx.doi.org/10.4103/dshmj.dshmj_13_24.

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Breast myxoid fibroadenoma (MFA) is a rare entity characterized by hypocellular myxoid stroma and is either sporadic or associated with the Carney complex, an inherited disorder caused by PRKAR1A-inactivating germline mutations. Here, we present the case of a 17-year-old girl who presented with a 3-cm mass in her left breast, suggestive of fibroadenoma. The mass was surgically excised, and histopathology revealed MFA. We sought to review breast MFA and compare it to conventional fibroadenoma.

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16

Perin, Matheus Yung, Leonardo Antunes Castrillon da Fonseca, Viviane Cristina Oliveira, Carlos Bernardo Cola, Luciana Marques da Silva, and Leonardo Amorim Rizzo. "Complex Fibroadenoma: a Cystic Neoplasia Report Case." Journal of Health Sciences 23, no. 4 (2021): 345–48. http://dx.doi.org/10.17921/2447-8938.2021v23n4p345-348.

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AbstractFibroadenoma is the most common breast tumor in young woman. It is considered a non-malignant tumor, showing hyaline component and a biphasic stroma and epithelial process, thus, it is similar to phyllode tumor revealing intralobular stroma. The cystic changes in a complex fibroadenoma may mimic a carcinoma, therefore it may represent some problems in images interpretation, and it may enlarge the risk of cancer development. This is a description of a case report with literature review. A 21-year-old female patientwith no history of breast cancer in family, presented a palpable lump in

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17

Ekundina, Olakayode V., Chiamaka C. Ejelue, Ondokeyi P. Apulu, and Ore-oluwa O. Ayodele. "Cell Proliferation, Contact Inhibition, and Apoptosis Profiling in a Benign and Malignant Breast Lesion." International Journal of Oncology Research 5, no. 1 (2022): 1–6. https://doi.org/10.23937/2643-4563/1710034.

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Introduction: Monitoring and diagnosis of benign or premalignant breast lesions as it progresses to a malignant condition is very necessary for its ability to predict or curb the progression of a breast lesion to the malignant condition and Immunohistochemistry has been proven to be a useful tool in achieving this as immunohistochemical markers are corresponding and specific in nature. Objectives: The primary objective of this case-control study is to study the expression of KI67, E-cadherin, and P53 in normal breast tissues, fibroadenomas, and Invasive Ductal adenocarcinoma and to determine t

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18

Jabeen, Nusrat, Hussain Adnan Abdulla, Mohamed Ayed Abushwemeh, Asma Alqaseer, and Amal Alrayes. "Giant fibroadenoma of the breast: a benign breast mass mimicking malignancy." International Surgery Journal 8, no. 4 (2021): 1391. http://dx.doi.org/10.18203/2349-2902.isj20211332.

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Fibroadenoma is a common benign lesion of the breast that usually occurs in young females. Giant fibroadenoma of the breast is a rare benign pathology, which is defined as fibroadenoma greater than 5 cm in size and/or weighs more than 500 g. It is usually found in adolescent women. A 37-year-old woman undergoing treatment for infertility was referred to the breast clinic with an ulcerating left breast lump that had progressively increased in size. Examination showed a fungating left breast mass that obliterated the nipple-areola complex. Ultrasound showed a large soft tissue mass in the left b

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19

International, Journal of Medical Science and Innovative Research (IJMSIR). "Osseous metaplasia in a complex fibroadenoma, A rare finding - A case report with review of literature." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 3 (2024): 91–94. https://doi.org/10.5281/zenodo.15402575.

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<strong>Abstract</strong> <strong>Introduction:</strong> Osseous metaplasia is one of the rarest pathology in breast lesions. Majority of cases are seen in malignant breast lesions and very few are mentioned with benign lesions of breast. Hence, careful diagnosis is necessary to differentiate it from malignant lesions in the breast.                                            &n

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20

Olaofe, Olaejirinde O., Ademola I. Soremekun, and James O. Oladele. "Fibroepithelial tumours of the breast seen in a tertiary health centre in southwestern Nigeria." International Journal of Research in Medical Sciences 11, no. 8 (2023): 2789–95. http://dx.doi.org/10.18203/2320-6012.ijrms20232405.

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Background: Fibroepithelial tumours of the breast are mainly fibroadenoma and phyllodes tumour. Our objective was to describe the clinical and pathological features of benign fibroepithelial tumours and then compare our findings with reports from other parts of the world. Methods: We carried out a retrospective study of all benign fibroepithelial tumours diagnosed in the Department of Morbid Anatomy and Forensic Medicine of Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria from January 1, 2018 to December 31, 2022. Results: A total of 538 cases of fibroadenoma we

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Ahmed, Qazi N., Syed O. Chand, Riyaj S. Patel, and Hingora M. Saquib. "Fibroadenoma with pseudo angiomatous stromal hyperplasia and hamartoma of the breast: a case report." International Journal of Research in Medical Sciences 13, no. 7 (2025): 3023–26. https://doi.org/10.18203/2320-6012.ijrms20252042.

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Pseudo angiomatous stromal hyperplasia (PASH) is an uncommon benign proliferative lesion of the breast stroma, characterized histologically by interanastomosing slit-like spaces within a dense collagenous background, mimicking vascular channels but lacking true endothelial lining. It was first described in 1986 by Vuitch, Rosen, and Erlandson, who reported nine cases of breast masses simulating vascular tumors, composed of proliferative mammary stromal tissue. Although PASH is often an incidental microscopic finding in breast biopsies, it can occasionally present as a palpable mass, particular

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22

Mele, Marco, Pernille Vahl, Jonas Amstrup Funder, Anne Schmidt Sorensen, and Vibeke Jensen. "Apocrine carcinoma arising in a complex fibroadenoma: A case report." Breast Disease 34, no. 4 (2014): 183–87. http://dx.doi.org/10.3233/bd-140365.

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23

&NA;. "A need to subclassify mammary fibroadenoma into “Complex” and “noncomplex” subtypes?" Advances in Anatomic Pathology 2, no. 2 (1995): 125. http://dx.doi.org/10.1097/00125480-199503000-00045.

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Muthusamy, RajeshwariK, and SangitaS Mehta. "Borderline phyllodes tumor arising in a complex fibroadenoma with extensive squamous metaplasia: A complex pathological presentation." Indian Journal of Medical and Paediatric Oncology 39, no. 2 (2018): 266. http://dx.doi.org/10.4103/ijmpo.ijmpo_46_17.

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25

Victor, Ekundina, Ayowole Oladele, Awe Praise, et al. "Expression of CEA, CA125 and P16INK4A in the Normal Breast, Fibroadenoma and Invasive Adenocarcinomas of the Breast." Alq J Med App Sci 5, no. 1 (2022): 78–88. https://doi.org/10.5281/zenodo.5949210.

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Aims. The incidence rate of breast cancer is higher in developed countries and it varies greatly with race and ethnicity. The p16INK4A, a tumor suppressor gene, CA125, a gene involved in the arrest of the cell cycle and CEA, a cellular adhesion molecule are markers that have been expressed in breast cancer cases in previous studies, however this study was aimed at studying the various expression patterns of these markers at different stages of breast cancer starting from the normal breast, fibroadenoma down to the invasive adenocarcinoma of the breast. Sample and method. A total of 65 breast t

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Bhandare, Shruti, Varsha Munj, Dattaraj Budkule, and DrTanay Gangurde. "Synchronous Complex Fibroadenoma and Tubular Adenoma of the Breast in an Adolescent Female: A Rare Case Report." International Journal of Science and Research (IJSR) 11, no. 7 (2022): 518–21. http://dx.doi.org/10.21275/sr22705112135.

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Alessandrini, Lara, Dalia Gobbi, Giovanni Franco Zanon, Patrizia Dall’Igna, Giovanni Cecchetto, and Rita Alaggio. "Concurrent fibroadenoma and intraductal papilloma – A recurring complex lesion in a premenarcheal girl." Pathology - Research and Practice 209, no. 2 (2013): 120–23. http://dx.doi.org/10.1016/j.prp.2012.10.011.

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28

Alatise, Olusegun Isaac, Ganiyat Oluwatoyin Omoniyi-Esan, Olukayode O. Lawal, Abdulrusheed Kayode Adesunkanmi, and Augustine Agbakwuru. "Relating tissue selenium to anthropometric and receptor status in Nigerian patients with breast cancer." Journal of Clinical Oncology 30, no. 15_suppl (2012): e12022-e12022. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e12022.

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e12022 Background: The aim of this study was to identify the relationship of tissue selenium to anthropometric data and receptors status among Nigerian women with breast cancer. Methods: Consecutive consenting patients who had histologically confirmed breast cancer and fibroadenoma at Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, were recruited for the study. One gram of disease breast tissue was taken for selenium analysis from the subjects. The specimens were analyzed using graphite furnace atomic absorption spectrometer. Subjects’ demographics, anthropometric and breast can

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29

Nassar, Aziza, Daniel W. Visscher, Amy C. Degnim, et al. "Complex fibroadenoma and breast cancer risk: a Mayo Clinic Benign Breast Disease Cohort Study." Breast Cancer Research and Treatment 153, no. 2 (2015): 397–405. http://dx.doi.org/10.1007/s10549-015-3535-8.

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Ng, Wei Wei, and Shanty Velaiutham. "CARNEY COMPLEX." Journal of the ASEAN Federation of Endocrine Societies 39, S1 (2024): 22–23. https://doi.org/10.15605/jafes.039.s1.032.

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INTRODUCTION/BACKGROUND Carney complex (CNC) is a rare multiple endocrine neoplasia characterized by spotty skin pigmentation, myxomas and endocrine overactivity. We report a case of a young female with multiple typical manifestations of CNC over the past 12 years, including bilateral primary pigmented nodular adrenocortical disease, bilateral breast ductal adenoma, cardiac myxoma and thyroid nodule. CASEThis female first presented at age 28 for secondary amenorrhea, weight gain and uncontrolled hypertension. She had pigmentation over her lips and features of Cushing syndrome, such as facial p

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Muhammad Shah, Ainul Hadi, Muhammad Iftikhar, Imranuddin Khan, Muhammad Zeb, and Shehzad Akbar Khan. "Evaluation of benign breast diseases." Professional Medical Journal 30, no. 04 (2023): 432–36. http://dx.doi.org/10.29309/tpmj/2023.30.04.7391.

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Objectives: To find the frequency of benign breast diseases presented to outdoor patient department and to exclude malignancy. Study Design: Descriptive Case Series Study. Setting: Department of General Surgery, Hayatabad Medical Complex, Peshawar. Period: July 2021 to June 2022. Material & Methods: Ninety five females presented to OPD with complaints of breast pain, lumpy, nipple and breast discharge. All patients were investigated through triple assessment. Mammography and trucat biopsy were performed in selected cases. Diagnosed cases of breast cancer and those picked up through investi

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Meghji, Nadir A., Ibrahim Mkoma, Advera Ngaiza, Paul Itule, and Ally H. Mwanga. "Mammoplasty With Nipple-sparing Goldilocks Technique in Unilateral Gigantic Juvenile Fibroadenoma." Plastic and Reconstructive Surgery - Global Open 13, no. 6 (2025): e6894. https://doi.org/10.1097/gox.0000000000006894.

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Summary: Juvenile fibroadenoma (JFA) represents a distinct subtype of fibroepithelial breast lesions that predominantly affect adolescents and young women. Unilateral JFAs are a rare condition in which surgical intervention focusing on oncoplastic reconstruction may be indicated in cases of severe symptoms or significant cosmetic deformity, with careful consideration of patient age, breast development stage, and long-term outcomes. However, there is limited literature on their surgical management aimed at delivering good aesthetic results to these young women. We report a case of a 15-year-old

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Madjar, Christin, James Seabert, Annette Fisseler-Eckhoff, et al. "Relevance of B3 lesions in breast diagnosis – frequency and therapeutic consequences." Senologie - Zeitschrift für Mammadiagnostik und -therapie 15, no. 03 (2018): 153–59. http://dx.doi.org/10.1055/a-0646-6554.

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AbstractWith improvements in breast imaging and minimally invasive interventions, detection of early breast cancer has increased. However, with the improved diagnostic capabilities, the risk of false-positive benign lesions as well as lesions classified as B3 by histopathology has also increased. Varying rates of malignancies are associated with B3 lesions, raising the question of whether such lesions should always be surgically removed. The results of our retrospective analysis should assist in this decision-making process.307 core needle or vacuum-assisted needle biopsies in which B3 lesions

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Jesrani, Ameet, Pari Gul, Nida Khan, Seema Nayab, and Fahmida Naheed. "Ultrasound Employed to Detect Breast Lumps among Symptomatic Patients in Tertiary Care Hospital." Journal of Bahria University Medical and Dental College 10, no. 4 (2020): 296–300. http://dx.doi.org/10.51985/jbumdc2020032.

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Objective: To assess different pathological breast lesions in ultra sound in a subgroup of population. Study design and setting: It was a cross sectional study conducted at Bolan Medical Complex Hospital Quetta, Pakistan from June 2018 to January 2019. Methodology: Total 103 patients with breast swelling, pain and discharge were targeted. Gray scale and Doppler Ultrasound of breast followed by FNAC/biopsy of breast lesion was performed. Data presented as mean ± standard deviation for continuous variables and frequency with percentages for categorical variables. Results: Out of 48 clinically pa

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Jaksa, Suherman, Muhammad Fachri, Andriyani Andriyani, Nurmalia Lusida, Gofur Ahmad, and Muhammad Labib. "Risk factors for fibroadenoma mammae (FAM) among adult women at the South Tangerang General Hospital in Indonesia." Trends in Immunotherapy 8, no. 1 (2024): 6410. http://dx.doi.org/10.24294/ti.v8.i1.6410.

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A frequent benign breast tumor, fibroadenoma mammae (FAM), has extra stromal and epithelial components in the breast tissue. Despite not being fatal, FAM increases breast cancer risk, highlighting the necessity to recognize it. Estrogen and progesterone levels during menstruation, pregnancy, and lactation may alter FAM development. Therefore, this study examines FAM risk variables in adult women at South Tangerang Regional General Hospital, Indonesia. Adult women in General Hospital of South Tangerang City, Indonesia were studied using a case-control design with 85 cases and 85 controls. South

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Saxena, Shilpi, Kachnar Varma, Deep Kumar Raman, and Vivek Upadhyay. "Rare findings in a common tumor: A case of complex fibroadenoma with secondary changes in a young female." Indian Journal of Pathology and Oncology 7, no. 2 (2020): 327–30. http://dx.doi.org/10.18231/j.ijpo.2020.064.

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37

Sharif, Aamir, Tahira Tabassum, Muhammad Riaz, Muhammad Akram, and Naveed Munir. "Cytomorphological patterns of palpable breast lesions diagnosed on fine needle aspiration cytology in females." European Journal of Inflammation 18 (January 2020): 205873922094614. http://dx.doi.org/10.1177/2058739220946140.

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Breast cancer is the most common malignant tumor and is a leading cause of death worldwide. This study was planned to find out the frequencies of various types of lesions from palpable breasts of female patients through fine needle aspiration cytology. This retrospective study was carried out during December 2017 to May 2018 on 100 female patients presenting with palpable breast mass at University Medical Complex & Research Center, Sargodha, Pakistan. Following written informed consent from patients, a detailed history, patient age, and clinical examination were recorded. The fine needle a

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38

Makis, William, Anthony Ciarallo, Marc Hickeson, and Vilma Derbekyan. "Rapidly Growing Complex Fibroadenoma With Surrounding Ductal Hyperplasia Mimics Breast Malignancy on Serial F-18 FDG PET/CT Imaging." Clinical Nuclear Medicine 36, no. 7 (2011): 576–79. http://dx.doi.org/10.1097/rlu.0b013e318217569e.

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39

M, Afodun A., Eze E. D, Quadri K. K, et al. "Comparative sonographic review of benign and malignant breast masses." Journal of Solid Tumors 8, no. 1 (2018): 42. http://dx.doi.org/10.5430/jst.v8n1p42.

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Complex breast masses may appear as suspicious ultrasound findings that usually warrant biopsy. Ductal cell carcinoma in-situ (DCIS) is a form of breast cancer with a non-uniform appearance and malignant potential. A longitudinal review of mammary gland ultrasound (with high frequency transducer) within a three-year period was conducted. Differential diagnosis of fibroadenoma, lactating adenoma, mastitis, galactocele, breast cancer, abscess and “general” masses greater than 16 mm in diameter was stratified. Based on the breast imaging reporting in data system (BIRADS), lesions were classified

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Madhumita Paul, Manisha Mahata, Sajeeb Mondal, Rajashree Pradhan, and Bidisha Chakraborty. "Cytohistological Evaluation of Unusual Male Breast lesions: A Case Series from a Tertiary Care Centre." Indian Journal of Public Health Research & Development 15, no. 1 (2024): 180–84. http://dx.doi.org/10.37506/tyzxrz16.

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Introduction: Pathologic lesions of male breast are not as common as its female counterpart.In this study we have reported six cases of unusual pathological lesions of male breast presenting clinically asbreast lump studied by Fine Needle Aspiration Cytology (FNAC) with histologic correlation.Method: 6 male patients were studied who presented to us with breast lump and had FNAC done with subsequenthistopathological correlation.Result: Out of 6 cases, 3 were fibromatosis (desmoid-type), 2 cases of invasive carcinoma involving both breastswith axillary lymph node metastasis and 1 case of complex

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Wilkinson, T. Raju Vinay, Anupama Ashok Kashid, and Rajiv Krishnarao Sonarkar. "A massive phylloides tumor in the breast: case report and literature review." International Surgery Journal 7, no. 7 (2020): 2425. http://dx.doi.org/10.18203/2349-2902.isj20202863.

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Phylloides tumor (PT) is a rare fibro epithelial neoplasm comprising <1% of all breast tumors. Clinical spectrum ranges from benign (B), borderline (BL), and locally recurrent to malignant (M) and metastatic type. Phylloides tumors originate from the connective tissue of the breast, so the malignant phylloides are histologically sarcomas. We are reporting a massive phylloides tumor in a 45 years old female. She presented with a huge breast mass occupying almost the whole of the right breast with two areas of pressure necrosis, on the overlying skin. She noticed a small lump 7 months ago in

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Nerune, Savitri M., Prasad Sasnur, Sayandeep K. Das, and Kezia Anna Jacob. "Myofibroblastoma of the breast mimicking carcinoma: a diagnostic challenge with a crucial role for histopathology and immunohistochemistry." BMJ Case Reports 18, no. 1 (2025): e263503. https://doi.org/10.1136/bcr-2024-263503.

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Myofibroblastoma is a rare mesenchymal tumour known for its benign nature but complex diagnostic pathway. A woman in her 40s presented with a painless breast mass, initially reported as a fibroadenoma on ultrasound mammography and as a benign to borderline phyllodes tumour on fine needle aspiration cytology. Contrast-enhanced CT was reported as carcinoma of the breast with Breast Imaging and Reporting Data System (BIRADS)-6. Based on these findings, a modified right radical mastectomy was performed. This case highlights the limitations of radiological modalities in diagnosing myofibroblastoma

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A. AL-Dujaily, Esraa, Liwaa H. Al-Kelabi, Ali Jabir Neima Alkhafaji, and Esraah S.M.Al-Harris. "HER-2/neu overexpression in correlation to Vascular Endothelial Growth Factor ,grade and stage of Non other wised specified Invasive ductal carcinoma." AL-QADISIYAH MEDICAL JOURNAL 6, no. 10 (2017): 27–37. http://dx.doi.org/10.28922/qmj.2010.6.10.27-37.

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This study aimed to assess the significance of human epidermal growth factor (HER-2/neu) protein overexpression and its possible correlation with vascular endothelial growth factor (VEGF),grade and stage in human non otherwise specified breast cancer. The present investigation was performed over a period starting from November 2008 to January 2009 .Formalin fixed, paraffin-embedded blocks from 30 patients with breast cancer were included in this study. A group of 15 patients with benign breast lesions (fibroadenoma) was included as a comparative group and 15 normal breast tissue sections were

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Abdelmalak, M., W. Jeck, R. C. Bentley, R. E. Factor, L. H. Rosenberger, and D. E. Peterson. "Case Report: Primary Alveolar Soft Part Sarcoma of the Breast." American Journal of Clinical Pathology 158, Supplement_1 (2022): S42. http://dx.doi.org/10.1093/ajcp/aqac126.080.

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Abstract Introduction/Objective Alveolar soft part sarcoma (ASPS) is an exceedingly rare malignant neoplasm, typically arising in the lower limbs or the head and neck region of children and young adults. Very few cases of primary ASPS have been reported arising in the breast. Methods/Case Report A 16-year-old female presented with a slowly growing mass of the left breast for three years. Clinical and imaging features were initially consistent with a fibroadenoma. Palpable increase in size prompted repeat ultrasound revealing a 3.4 cm oval, complex, cystic and solid mass. Due to its complexity

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Gallowitsch, H. J., D. Kogler, E. Kresnik, P. Mikosch, I. Gomez, and P. Lind. "Tc-99m-Tetrofosmin Scintimammography: A Prospective Study in Primary Breast Lesions." Nuklearmedizin 35, no. 06 (1996): 225–29. http://dx.doi.org/10.1055/s-0038-1629780.

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SummaryDespite low specificity routine mammography is the method of choice to screen women for breast cancer. In addition high frequency ultrasonography (US) or magnetic resonance imaging (MRI) can improve breast cancer diagnosis. However there is a lack of conventional imaging to improve the high rate of false positive results that make biopsy or surgery necessary. Aim: The purpose of our study was to evaluate prospectively the sensitivity, specificity, PPV and NPV of scintimammography with a new cationic complex Tc-99m-tetrofosmin. Methods: Fourtyeight patients in whom mammography and/or hig

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Edwards, A., C. Bermudez, G. Piwonka, et al. "Carney's Syndrome: Complex Myxomas. Report of Four Cases and Review of the Literature." Cardiovascular Surgery 10, no. 3 (2002): 264–75. http://dx.doi.org/10.1177/096721090201000314.

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Cardiac myxomas are rare tumors. They usually appear as a sporadic isolated condition in the left atrium of middle-aged women with no other coincidental pathology. Carney and others have described in young people a special complex group of cardiac myxomas associated to a distinctive complex pathology, giving identity to the “Syndrome Myxoma” or “Carney's Syndrome”. Four additional cases of this syndrome, treated from 1977 to 1999 at the Hospital Clínico de la Universidad de Chile are presented here with a comprehensive review of the literature, accumulating 100 cases. The main features of our

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Johnson AB, Aishat ON, Adedotun OA, Salewa OE, Adewale A, and Adebola A. "An audit of two hundred and fifty consecutive breast biopsies in Nigerian women." Ibom Medical Journal 18, no. 2 (2025): 294–303. https://doi.org/10.61386/imj.v18i2.668.

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Objective: This study aims to audit the clinical and pathological features of patients with breast lumps seen at the University of Medical Sciences Teaching Hospital, Akure Complex, Ondo State, Nigeria. Methods: A retrospective descriptive cross-sectional study was conducted at the surgical outpatient department of the University of Medical Sciences Teaching Hospital, Akure Complex over a three-year duration between May 2018 and April 2021. Histopathological reports of all breast specimens received and processed during the study period were retrieved from a computer database and analyzed using

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Calderón-Garcidueñas, Ana Laura, Mónica Sanabria-Mondragón, Lourdes Hernández-Beltrán, Noé López-Amador, and Ricardo M. Cerda-Flores. "Mammographic Breast Density Patterns in Asymptomatic Mexican Women." Radiology Research and Practice 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/127485.

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Breast density (BD) is a risk factor for breast cancer.Aims. To describe BD patterns in asymptomatic Mexican women and the pathological mammographic findings.Methods and Material. Prospective, descriptive, and comparative study. Women answered a questionnaire and their mammograms were analyzed according to BI-RADS. Univariate () and conditional logistic regression analyses were performed.Results. In 300 women studied the BD patterns were fat 56.7% (170), fibroglandular 29% (87), heterogeneously dense 5.7% (17), and dense pattern 8.6% (26). Prevalence of fat pattern was significantly different

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Shanmugam, Subbiah, Sujay Susikar, and Radha Siva Bharath. "Patient satisfactory score post oncoplastic breast surgery- our institutional experience." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 5 (2023): 1370–73. http://dx.doi.org/10.18203/2320-1770.ijrcog20231226.

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Background: Surgical management of breast cancer is rapidly evolving with increasing importance on techniques to preserve patient’s quality of life and post treatment cosmesis. Oncoplastic breast surgery (OBS) combines oncologic principles with plastic surgery techniques to improve cosmetic results by immediate breast reconstruction at the time of surgery. We aimed to evaluate patient reported satisfaction using questionnaire following OBS. Methods: This was a prospective observational study of 25 patients who underwent oncoplastic breast surgery at the department of surgical oncology, Governm

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Autenshlyus, Alexander I., Sergey A. Arkhipov, Tatiana A. Kunts, et al. "Cytokine profiles of tumor supernatants in invasive ductal cancer and fibroadenoma of the breast and its relationship with VEGF-A expression in the tumors." International Journal of Immunopathology and Pharmacology 30, no. 1 (2017): 83–88. http://dx.doi.org/10.1177/0394632016681306.

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Interrelations between cytokines, produced by invasive ductal carcinoma (IDC) and fibroadenoma (FA) of the breast, and angiogenic growth factor VEGF-A, expressed in IDC and FA, were investigated. The analysis of the cytokine profiles of IDC and FA was performed by cultivation of tumor biopsy specimens in vitro. Testing of the cytokine-producing reserve of the tumors for production of VEGF-A was conducted by culturing samples of IDC and FA in a medium containing polyclonal activator (a complex of phytohemagglutinin, concanavalin A, and lipopolysaccharide). Levels of cytokines and growth factors

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