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1

Api, A. M., D. Belsito, D. Botelho, et al. "The RIFM approach to evaluating Natural Complex Substances (NCS)." Food and Chemical Toxicology 159 (January 2022): 112715. http://dx.doi.org/10.1016/j.fct.2021.112715.

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2

Н.Ю., Чеснокова, Приходько Ю.В., Левочкина Л.В., Кузнецова А.А. та Фадеева М.Е. "НАТУРАЛЬНЫЙ КОНЦЕНТРИРОВАННЫЙ КРАСИТЕЛЬ, СОДЕРЖАЩИЙ КОМПЛЕКС АНТОЦИАНОВЫХ ПИГМЕНТОВ И ПЕКТИНОВЫХ ВЕЩЕСТВ". Bulletin of KSAU, № 12 (18 грудня 2019): 160–68. http://dx.doi.org/10.36718/1819-4036-2019-12-160-168.

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Изучено влияние температуры и ультразвука на интенсивность извлечения антоцианового пигмента и пектиновых веществ. Показано, что спектры, описывающие интенсивность извлечения антоцианового пигмента черной смородины, имеют два максимума поглощения при длинах волн 510 и 280 нм. Установлено соответствие максимумов поглощения антоцианового пигмента длине волны 510 нм и пектиновых веществ, ассоциированных с полифенолами, длине волны 280 нм. Показано, что наиболее полно экстрагирование антоцианового пигмента и пектиновых веществ происходит при температуре 65 °С в течение 30 мин. Увеличение температу
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3

Špinarová, Š., and K. Petříková. "Variability of the content and quality of some active substances within Achillea millefolium complex." Horticultural Science 30, No. 1 (2011): 7–13. http://dx.doi.org/10.17221/3811-hortsci.

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The present paper compares the production of active substances in different subspecies of Achillea millefolium complex growing in the Czech Republic. Representatives of 7 subspecies of A. millefolium complex (A. setacea Waldst. et Kit., A. asplenifolia Vent., A. pratensis Saukel et Langer, A. collina Rchb., A. styriaca Saukel et Langer subsp. bohemica, A. millefolium subsp. millefolium, A. pannonica Scheele) and several natural hybrids of Achillea L. were collected from 75 natural habitats in different parts of the Czech Republic. Plants were cultivated to investigate plant growth and contents
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4

Kochetov, Andrei, Valentin Minakov, Elena Fisunova, Tatyana Lavrenova, and Luybov Filonenko. "Acoustic synthesis of feed proteins under conditions of a complex ultrasonic field." E3S Web of Conferences 273 (2021): 13004. http://dx.doi.org/10.1051/e3sconf/202127313004.

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Liquid waste of food industry enterprises contains various valuable organic substances of natural origin, which can be rationally used to obtain feed proteins. The problem of using valuable substances from food waste solves the problem of using biotechnological methods in order to use methods of accumulating biomass, enzymes, vitamins, etc. The biomass of unicellular microorganisms formed in the process of cultivation can be a raw material for obtaining feed additives and other biologically active substances.
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5

Warren, Richard M. "Synthesizing complex sensations from simple components." Behavioral and Brain Sciences 31, no. 1 (2008): 90–91. http://dx.doi.org/10.1017/s0140525x0800352x.

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AbstractThe target article suggests that taste is not based on the traditional four basic tastes, but rather is a continuum subserved by cross-fiber integration. This commentary describes evidence indicating that the traditional concept is valid, and that with suitable precautions, it is possible to match natural substances using mixtures representing fundamental tastes.
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Adekenov, S. M., А. N. Zhabayeva, and G. М. Baisarov. "Water-Soluble Substances of Arglabin." Eurasian Chemico-Technological Journal 22, no. 3 (2020): 205. http://dx.doi.org/10.18321/ectj971.

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The article discusses the results of a study of the water solubility of natural sesquiterpene lactone arglabin, in particular, its ability to complex formation with complexing agents polyvinylpyrrolidone, the disodium salt of glycyrrhizic acid, magnesium carbonate. Mechanocomposites with polyvinylpyrrolidone and disodium salt of glycyrrhizic acid, which have increased water solubility, were obtained by the method of mechanochemical treatment of arglabin native. At the same time, the best result of dissolution in water is achieved by a two-hour treatment with polyvinylpyrrolidone and with disod
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7

Babina, Liudmila V., and Ksenia E. Lukina. "English deadjectival nouns as models of knowledge representation about the world." Current Issues in Philology and Pedagogical Linguistics, no. 2(2021) (June 25, 2021): 176–85. http://dx.doi.org/10.29025/2079-6021-2021-2-176-185.

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From the position of a cognitive approach the authors consider English deadjectival nouns, what involves identifying and describing knowledge domains represented by these language units in English language culture. The study is carried out on the material of deadjectival nouns, which are fixed in English dictionaries and selected by a continuous sampling method. A set of methods is used, the main of which are methods of conceptual-definitional and cognitive-matrix analysis. As a result of the study, it is revealed that English deadjectival nouns represent the structure of knowledge of an integ
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8

Landina, L. N. "Standardization of Dry Extract of Pumpkin Pulp Juice, Which Has a Hypolipidemic Effect on the Content of Β-Carotene". Medicina 9, № 1 (2021): 79–92. http://dx.doi.org/10.29234/2308-9113-2021-9-1-79-92.

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The objective is to standardize the content of β-carotene – one of the principal active substances with sufficient hypolipidemic activity in the resultant original product. Search for natural biologically active substances having a hypolipidemic effect is one of the topical questions in modern pharmacy. Most of the research is carried out by means of isolating individual substances from the plant object. We propose to study a native phytocomplex obtained from pumpkin pulp – a dry extract of pumpkin pulp juice. The following materials and methods were used: laboratory-obtained dry extract of pu
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9

Bondareva, Lydia, and Nadezhda Kudryasheva. "Direct and Indirect Detoxification Effects of Humic Substances." Agronomy 11, no. 2 (2021): 198. http://dx.doi.org/10.3390/agronomy11020198.

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The review summarizes studies on the detoxification effects of water-soluble humic substances (HS), which are products of the natural transformation of organic substances in soils and bottom sediments that serve as natural detoxifying agents in water solutions. The detoxifying effects of HS on microorganisms are quite complex: HS neutralize free pollutants (indirect bioeffects) and also stimulate the protective response of organisms (direct bioeffects). Prospects and potential problems of bioluminescent bacteria-based assay to monitor toxicity of solutions in the presence of HS are discussed.
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10

Napiórkowska, Alicja, and Marcin Kurek. "Coacervation as a Novel Method of Microencapsulation of Essential Oils—A Review." Molecules 27, no. 16 (2022): 5142. http://dx.doi.org/10.3390/molecules27165142.

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These days, consumers are increasingly “nutritionally aware”. The trend of “clean label” is gaining momentum. Synthetic additives and preservatives, as well as natural ones, bearing the E symbol are more often perceived negatively. For this reason, substances of natural origin are sought tfor replacing them. Essential oils can be such substances. However, the wider use of essential oils in the food industry is severely limited. This is because these substances are highly sensitive to light, oxygen, and temperature. This creates problems with their processing and storage. In addition, they have
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11

Medetkhanov, Fazil A., Kseniya V. Muravyova, Dmitriy P. Khadeev, Irina A. Konakova, and Elmira S. Yarullina. "Comparative assessment of the parameters of acute toxicity of natural products." BIO Web of Conferences 17 (2020): 00146. http://dx.doi.org/10.1051/bioconf/20201700146.

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The paper presents the results of comparative assessment of the parameters of acute toxicity of complex plant agents under such laboratory codes as CDP, Bronchelp and a phytopropoletic agent KNA for parenteral application, as well as a complex agent KV for use per os. The studies revealed that the single intramuscular administration of agents from natural components CDP, Bronchelp and KNA to laboratory rats in the maximum permissible dose do not have a general toxic effect. Similar results were obtained by oral use of a complex agent KV. According to the results, the tested agents are classifi
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Krotova, Irina, and Vladimir Boev. "NATURAL DYES FROM CONIFEROUS PLANT DEBARKING WASTE." Trade, service, food industry 1, no. 4 (2022): 406–20. http://dx.doi.org/10.17516/2782-2214-0029.

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The need to reduce greenhouse gas emissions into the atmosphere, decarbonization of industrial production makes it urgent to improve many technological schemes, including schemes for complex processing of plant resources. The authors of the article consider the possibility of recycling multi-tonnage waste bark of Siberian coniferous plants to obtain a marketable product – a natural dye for the textile industry. The study showed that the complex of coloring substances of the bark of Siberian fir, spruce and larch is mainly represented by flavonoid compounds, primarily quercetin, dihydroquerceti
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13

Dzhenis, Y. A., and I. I. Tuber. "Integrated interrelationship of sewage sludges with absorbing complex of river Miass drainage area." Water Practice and Technology 9, no. 4 (2014): 441–44. http://dx.doi.org/10.2166/wpt.2014.041.

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Soil is a powerful and active absorber of many substances, assumes the pressure of industrial and municipal emissions and waste, and performs the important role of a buffer and a detoxicant. It accumulates heavy metals, pesticides, hydrocarbons and other chemical polluting substances and due to the soil absorbing complex (SAC) strongly captures and protects natural waters and the atmosphere from harm. Applying sewage sludges in our research will enable us to strengthen the capacity of SAC and to reduce the toxicity of heavy metals when they enter a reservoir via a drain from anthropogenically
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14

Sokolova, Elena Nikolaevna, Tat'yana Vladimirovna Yuraskina, Yuliya Aleksandrovna Borshcheva, Natal'ya Aleksandrovna Fursova, Anton Yur'yevich Sharikov, and Elena Mikhailovna Serba. "INFLUENCE OF BIOTECHNOLOGICAL FACTORS ON THE YIELD OF BIOLOGICALLY ACTIVE COMPOUNDS FROM SORBUS AUCUPARIA." chemistry of plant raw material, no. 3 (September 27, 2021): 291–300. http://dx.doi.org/10.14258/jcprm.2021037439.

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Currently, the diet of almost all population groups in Russia is characterized by a deficiency of vitamins, essential amino acids, macro- and micronutrients, as well as biologically active substances (flavonoids, carotenoids, etc.). Replenishment of the lack of these components in the diet of the population due to natural sources of plant origin is an important and actual task of national health care.
 The rational use of natural components of plant materials containing a wide range of natural biologically active substances using biocatalytic methods, as well as the selection of optimal c
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15

Gumerova, G. H., M. R. Vakhitov, and I. S. Dokuchaeva. "Methodological approaches for the efficient production of parapharmaceuticals based on wild raw materials." E3S Web of Conferences 247 (2021): 01055. http://dx.doi.org/10.1051/e3sconf/202124701055.

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The foundations of efficient production are laid at the stage of developing a high-tech product. The object of research is wild berries (lingonberry, honeysuckle, viburnum, cranberry, cloudberry, sea buckthorn, mountain ash, aronia), which are used as a source of a natural complex of biologically active substances and trace elements as the main substance of a new parapharmaceutical. The primary technological task of food engineering of paramarceuticals is the maximum extraction of biologically active substances of plant raw materials and their preservation in their native form during the warra
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16

Lee, Joonseop, Gyeol Ko, Junghoon Mok, and Yongwon Seo. "Complex Phase Behaviors and Structural Coexistence of Natural Gas Hydrates Containing Large-Molecule Guest Substances." Energy & Fuels 35, no. 7 (2021): 6081–89. http://dx.doi.org/10.1021/acs.energyfuels.0c04372.

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17

O’Melia, C. R., W. C. Becker, and K. K. Au. "Removal of Humic Substances by Coagulation." Water Science and Technology 40, no. 9 (1999): 47–54. http://dx.doi.org/10.2166/wst.1999.0440.

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Measurements and modeling of the adsorption of natural organic matter (NOM) on oxide surfaces are presented and compared. Agreement is good and supports the view that the adsorption of NOM on oxides depends significantly on complex formation reactions between specific sites on oxide surfaces and functional groups on the NOM. Coagulant requirements can and often are set by the total organic carbon (TOC) concentration in a water source. Frequently there is a stoichiometric relationship between the required coagulant dosage and the TOC of the water to be treated. Other important factors include p
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18

POPOV, A. I., V. N. ZELENKOV, M. V. MARKOV, et al. "HUMIC SUBSTANCES AND THE MECHANISM OF THEIR INFLUENCE ON THE PRODUCTION OF HIGHER GREEN PLANTS." SABRAO Journal of Breeding and Genetics 54, no. 4 (2022): 908–16. http://dx.doi.org/10.54910/sabrao2022.54.4.21.

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The latest research proposed a new point of view about the material composition of so-called 'humic substances,' isolated from natural objects (soils, peats, sapropels, and composts) by alkaline solutions, and presented the conceptual model of direct influence of 'humic substances' on biochemical and biophysical processes into plants. 'Humic substances' are essentially black liquor, i.e., a product artificially obtained because of the alkaline hydrolysis of organic material from natural objects. Black liquor consists of a complex mixture of a variety of organic compounds. According to the prop
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19

Degli Esposti, M., A. Ghelli, M. Ratta, D. Cortes, and E. Estornell. "Natural substances (acetogenins) from the family Annonaceae are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I)." Biochemical Journal 301, no. 1 (1994): 161–67. http://dx.doi.org/10.1042/bj3010161.

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Natural products from the plants of the family Annonaceae, collectively called Annonaceous acetogenins, are very potent inhibitors of the NADH-ubiquinone reductase (Complex I) activity of mammalian mitochondria. The properties of five of such acetogenins are compared with those of rotenone and piericidin, classical potent inhibitors of Complex I. Rolliniastatin-1 and rolliniastatin-2 are more powerful than piericidin in terms of both their inhibitory constant and the protein-dependence of their titre in bovine submitochondrial particles. These acetogenins could be considered therefore the most
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20

Losev, OM, HM Voytenko, NV Kurdil, et al. "Modeling of content of biologically active hepatoprotective substances in the composition of natural honey." One Health and Nutrition Problems of Ukraine 54, no. 1 (2021): 34–40. http://dx.doi.org/10.33273/2663-9726-2021-54-1-34-40.

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Aim. The search for ways to create hepatoprotective food additives based on biologically active substances of plant origin and bee honey is an important area of research in the field of biology and medicine. Materials and Methods. The material for the research was bees of Ukrainian breed (Apis mellifera sossimai). The process of enriching the natural properties of natural honey was carried out in a natural way through the bee family by feeding colonies of bees with a special composition of natural origin components based on Avéna satíva and Silibum marianum. Sieve honey with monofloral honey f
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21

Labbozzetta, Manuela, Paola Poma, and Monica Notarbartolo. "Natural Inhibitors of P-glycoprotein in Acute Myeloid Leukemia." International Journal of Molecular Sciences 24, no. 4 (2023): 4140. http://dx.doi.org/10.3390/ijms24044140.

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Acute myeloid leukemia (AML) remains an insidious neoplasm due to the percentage of patients who develop resistance to both classic chemotherapy and emerging drugs. Multidrug resistance (MDR) is a complex process determined by multiple mechanisms, and it is often caused by the overexpression of efflux pumps, the most important of which is P-glycoprotein (P-gp). This mini-review aims to examine the advantages of using natural substances as P-gp inhibitors, focusing on four molecules: phytol, curcumin, lupeol, and heptacosane, and their mechanism of action in AML.
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Bubenec, E. A., M. A. Volchkevich, E. N. Koroza, K. Kulakovskij, and G. G. Maksimenya. "PHYTOTHERAPY USE IN MODERN MEDICINE." Military Medicine, no. 3 (2021): 150. http://dx.doi.org/10.51922/2074-5044.2021.3.150.

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It is known that phytotherapy is a method of treating various human diseases, based on the use of medicinal plants and complex preparations from them. Medicinal plants can be used in fresh, dried form, as well as by isolating active substances from them with the help of simple processing, which preserves the structure of the natural complex. components (infusion, extract, etc.).
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Garsiya, Ekaterina Robertovna, Liliya Petrovna Myikots, Liliya Veniaminovna Ligay, Arnol'd Alekseyevich Shamilov, and Dmitriy Alekseyevich Konovalov. "QUALITATIVE CONTENT AND SOME PHYSICAL AND CHEMICAL PROPERTIES OF POLYSACCHARIDES FROM ONOPORDUM ACANTHIUM L. HERB." chemistry of plant raw material, no. 4 (December 14, 2021): 65–73. http://dx.doi.org/10.14258/jcprm.2021049074.

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Natural polymers are interesting as independent pharmaceutical substances also as complex drugs including herbal drugs. The aim of this work was determination of the main features of water-soluble polysaccharides (WSPS) and pectinic substances (PS) isolated from Onopordum acanthium L. herb for using as pharmaceutical substances. The following tasks were set to achieve this aim: determination of qualitative content of monosaccharides after previous acidic hydrolysis of fractions by paper chromatography, determination of molecular weight, isoelectric point, distribution coefficient, superficial
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Danilov, D. A., A. V. Griazkin, V. A. Sokolova, and I. V. Bacherikov. "The component composition of planted pine wood cultivated in the boreal zone." Nordic Pulp & Paper Research Journal 35, no. 4 (2020): 685–93. http://dx.doi.org/10.1515/npprj-2020-0058.

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AbstractThe present study analyzes the composition of pine wood cultivated on artificial plantations in the Leningrad Oblast (Region). Comparing to pine wood from natural stands, a smaller heartwood zone along the height of the pine trunk and a lower content of resinous substances are noted. The content of cellulose and lignin in the heartwood and sapwood of pine is distributed differently along the trunk. The distribution of pentosans and water-soluble substances in the heartwood and sapwood along the trunk is associated with the lignin complex. The component composition of the studied pine w
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Krizshanovsky, S. P., B. I. Geltser, T. A. Kuznetsova, E. V. Persiyanova, and T. S. Zaporozhets. "The effectiveness of combined therapy of dyslipidemia by atorvastatin and biologycally active substances from marine hydrobionts." Russian Journal of Biotherapy 16, no. 2 (2017): 97–102. http://dx.doi.org/10.17650/1726-9784-2017-16-2-97-102.

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Introduction. The perspective direction in therapy of dyslipidemia (DLP) is a complex application of biologycally active substances from marine hydrobionts. Objective. The purpose of research - to compare the lipidcorrective action of preparates based on biologically active substances from marine hydrobionts - fukolam and maristim - individually and in combination with atorvastatin in patients with DLP. Materials and methods. 250patients with DLP and 40 healthy donors were included in research. As medicines atorvastatin, fukolam, maristim were used. In the blood serum the levels of lipid spect
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Astanov, Salih, Askar Fayzullaev, Guzal Kasimova, and Iroda Raupova. "Resource-saving technology of carrot processing with the production of natural dye." IOP Conference Series: Earth and Environmental Science 1112, no. 1 (2022): 012088. http://dx.doi.org/10.1088/1755-1315/1112/1/012088.

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Abstract Complex carrot processing technology “Mirzoi krasny” along with concentrated and powdered natural dye rich in mineral elements and biologically active substances obtained carrot powder and transparent juice used in the food industry. Based on obtaining the absorption spectrum of dyes, it was found that the main coloring pigment of the dye, along with β, are also α and γ-carotenoids.A method of sterilization of concentrated carrot dye based on an IR gausted object has been developed.
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Piskorska-Jasiulewicz, Magdalena Maria, and Małgorzata Witkowska-Zimny. "Non-nutritional use of breast milk." Postępy Higieny i Medycyny Doświadczalnej 71 (October 4, 2017): 0. http://dx.doi.org/10.5604/01.3001.0010.5049.

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Mammals milk, in addition to nutrients, contains many biologically active substances including immunoglobulins, growth factors, cytokines, acute phase proteins, and antimicrobial and antiviral proteins. Thanks to its unique composition, for hundreds of years it is used in post-natal care, treatment of wounds, as well as to fight bacterial and viral infections. The discovery of stem cells and HAMLET complex in breast milk resulted in increased interest in human breast milk as a natural medicine. Milk therapy is devoid of side effects, and breast milk banks may serve as a potential source of mil
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Pavel, Procházka, Štranc Přemysl, Pazderů Kateřina, Štranc Jaroslav, and Vostřel Jan. "Effects of biologically active substances used in soybean seed treatment on oil, protein and fibre content of harvested seeds." Plant, Soil and Environment 63, No. 12 (2017): 564–68. http://dx.doi.org/10.17221/702/2017-pse.

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In 4-year trials, soybean seeds were treated with the following biologically active substances: Lignohumate B (a mixture of humic acids and fulvic acids); Lexin (a mixture of humic acids and fulvic acids enriched with auxins); brassinosteroid (a synthetic analogue of natural epibrassinolide 24) and so-called ‘Complex seed treatment’ (a mixture of a saturated solution of sucrose, Lexin, the fungicide Maxim XL 035 FS and an adjuvant on the basis of pinolene). After harvesting soybean seeds from the individual treatments, they were analysed for oil, protein and fibre contents. The results show th
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Ioshchenko, Yuliya, Viktor Kablov, and Gennady Zaikov. "Biodegradation of oil products in polluted soil by using the mixture of the polymer complex [chotisan–lactoserum protein]–active silt." Chemistry & Chemical Technology 2, no. 2 (2008): 123–28. http://dx.doi.org/10.23939/chcht02.02.123.

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Biodegradation processes of oil products in the polluted soil were studied by using the mixture of the polymer complex [chitosan – lactoserum protein]–active silt. It is shown that all these processes take place due to the synergism of the components which form part of the mixture; the use of the developed biomixture ensures the effective biodegradation of compound oil hydrocarbons, a high degree of cleaning soil from pollutions, except the possible secondary pollution of environment. As a result of biocomposting the cleaned ground containing biogenic substances fits in natural cycle and can b
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Arora, Swamita, Tanveer Naved, Sanjar Alam, Bhupendra Chauhan, and Harikesh Kalonia. "TLR 4 / MD2 Complex inhibitors potential therapeutic prospective for asthma and asthma exacerbation." Research Journal of Biotechnology 16, no. 11 (2021): 164–76. http://dx.doi.org/10.25303/1611rjbt164176.

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The feedback of our body to foreign particles is initially initiated by the innate immunity where the likes Toll- Like Receptors (TLRs), play an important role in the identification process. The identification of the trouble through the interaction of the receptor is the initial step to propagate the protective agents throughout the body. These interact action with the attacking pathogens like viruses and bacteria (PAMPs, pathogen-associated molecular patterns) or substances produced cells of the body which are injured (DAMPs, danger-associated molecular patterns) helping in the identification
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Panda, Siva S., and Nancy Jhanji. "Natural Products as Potential Anti-Alzheimer Agents." Current Medicinal Chemistry 27, no. 35 (2020): 5887–917. http://dx.doi.org/10.2174/0929867326666190618113613.

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Medicinal plants have curative properties due to the presence of various complex chemical substances of different composition, which are found as secondary metabolites in one or more parts of the plant. The diverse secondary metabolites play an important role in the prevention and cure of various diseases including neurodegenerative diseases like Alzheimer’s disease. Naturally occurring compounds such as flavonoids, polyphenols, alkaloids, and glycosides found in various parts of the plant and/or marine sources may potentially protect neurodegeneration as well as improve memory and cognitive f
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Nechytailo, Mykola, Olena Nahorna, and Yevhenii Kosiuk. "Defining the effect of the chemical concentration and solution pH on membrane chemical cleaning process." E3S Web of Conferences 109 (2019): 00061. http://dx.doi.org/10.1051/e3sconf/201910900061.

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In the process of treating natural water from surface sources, precipitated substances are tend to be deposited on the ultrafiltration membrane, either as suspended solids or as gel structures, formed by humic substances with metal salts. Hydraulic washes are unable to remove gelled structures from the surface of the membranes. Consequently, the phenomenon of gelation on the surface of the membrane causes gradual decrease in productivity, which is a negative factor. Chemical washing of membranes is generally used to remove the gel layer from the membrane surface. In this paper, the range of co
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Rubiolo, Patrizia, Cristina Casetta, Cecilia Cagliero, Hugues Brevard, Barbara Sgorbini, and Carlo Bicchi. "Populus nigra L. bud absolute: a case study for a strategy of analysis of natural complex substances." Analytical and Bioanalytical Chemistry 405, no. 4 (2012): 1223–35. http://dx.doi.org/10.1007/s00216-012-6537-y.

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Romanova, E. M., V. V. Romanov, V. N. Lyubomirova, L. A. Shadieva, and T. M. Shlenkina. "Vectors for the development of high-tech industrial aquaculture." BIO Web of Conferences 27 (2020): 00132. http://dx.doi.org/10.1051/bioconf/20202700132.

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The article discusses the prospects of optimizing the technology of growing African catfish in high-tech industrial aquaculture. The goal was to determine the range of biologically active substances that can increase the productivity, organoleptic qualities of fish grown in recirculating aquaculture systems and optimize their living conditions. For this purpose, a complex of biologically active substances was tested, including probiotics, prebiotics, amino acids, and natural sorbents. It was introduced into feed and added to the water of fish tanks. Studies have shown that the developed comple
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Yordanov, M., P. Dimitrova, S. Patkar, L. Saso, and N. Ivanovska. "Inhibition of Candida albicans extracellular enzyme activity by selected natural substances and their application inCandidainfection." Canadian Journal of Microbiology 54, no. 6 (2008): 435–40. http://dx.doi.org/10.1139/w08-029.

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Extracellular enzymes secreted by Candida albicans are claimed to be virulence factors responsible for penetration of the yeast into host cells. Substances able to inhibit lipolytic and proteinase activities of the fungus might be of therapeutic use in some pathologic conditions caused by C. albicans. In the present work, we have tested the influence of the flavonoid compounds apigenin and kaempferol, the indole alkaloid ibogaine, and the protoberberine alkaloid berberine on the in vitro enzyme activity of C. albicans. The substances showed complex suppressive effects concerning the processes
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36

Markarova, A. E., M. Yu Markarova, O. A. Razin, and S. M. Nadezhkin. "The microorganisms natural consortia effectiveness in the white cabbage crop cultivation." IOP Conference Series: Earth and Environmental Science 953, no. 1 (2022): 012035. http://dx.doi.org/10.1088/1755-1315/953/1/012035.

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Abstract The research on effectiveness of microbial consortia with growth-regulating and anti-pathogenic functions on the yield and quality of white cabbage had been carried out in the field conditions for 2 years. It was obtained that under N90P120K150, the use of the experimental biofungicide Tridem promoted an increase in nitrogen-fixing activity in the soil and a decrease in the infectious conditions in the rhizosphere under cabbage hybrids. The use of the experimental microbial complex BIS provided an increase in the mass of heads of cabbage, the accumulation of biologically active substa
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37

Shavrina, D. I., N. V. Nesterova, O. V. Nesterova, N. V. Birukova, and A. A. Iaroshenko. "Studying Possibilities of Using Beebread in Medicine with the Follow-Up Development of a Means to Improve Immunity." RUDN Journal of Medicine 23, no. 4 (2019): 412–17. http://dx.doi.org/10.22363/2313-0245-2019-23-4-412-417.

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In the course of the analysis of scientific literature, the composition of the bee bread containing biologically active substances (arginine, phenylalanine, isoleucine, leucine, lysine, methionine, threonine), mineral salts, trace elements and valuable vitamins that enhance immunity was studied. The complex of reactions recommended by the State Pharmacopoeia of the Russian Federation was used to determine the main groups of biologically active substances characteristic of natural raw materials. As an object of research, bee bread was used. The raw materials were identified: amino acids, hydrox
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38

Fitzke, B., and S. U. Geißen. "Sustainable removal of iodinated X-ray contrast media (XRC) by ozonation in a complex wastewater matrix – urine as example." Water Science and Technology 55, no. 12 (2007): 293–300. http://dx.doi.org/10.2166/wst.2007.426.

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Pharmaceutical and diagnostic substances like antibiotics, cytostatics and iodised X-ray contrast media (XRC) are well-known for not being metabolised and are excreted soon after application. As a result, these preparations are difficult to biodegrade and their adsorption behaviour is rather poor. Finally, the refractory properties of these substances are leading to an accumulation in the natural waterbody depending on the hydrological situation. The elimination of contrast media from urine and diluted urine solutions by ozonation was investigated using a bubble column reactor to remove and re
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39

Sakinah, Marda. "Use of Herbal Medicinal Products among Children." Eureka Herba Indonesia 4, no. 1 (2021): 156–59. http://dx.doi.org/10.37275/ehi.v4i1.29.

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The use of herbal medicinal products for the treatment and prevention of diseases has a long tradition over the world. The herbal medicinal products are defined as exclusively herbal active substances-contained medicinal products which used for prevention or treatment of disease. Because of its process, it chemically different defined substances in several aspects; mostly because they consist of complex multi-component mixtures which from the extraction of plant parts such as roots and leaves. Many substances could be used for relieving clinical symptoms among children. The perception that “na
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Pogarska, Viktoriya, Raisa Pavlyuk, Roman David Tauber, et al. "DEVELOPMENT OF THE EXTRACTION METHOD OF INACTIVE FORMS OF PECTIN SUBSTANCES FROM FRUITS TO EASY-DIGESTIBLE ACTIVE FORM DURING THE OBTAINING OF NANOFOOD." EUREKA: Life Sciences 6 (November 30, 2017): 57–64. http://dx.doi.org/10.21303/2504-5695.2017.00520.

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The aim of the work is development of a unique method for deep processing of fruits and vegetables with a high content of sparingly soluble pectin substances, which makes it possible to remove pectic substances from inactive form and transform them into an easily digestible active form when obtaining natural semi-finished products and food products in nanosized form. To achieve the aim, a complex effect on the raw material of steam-thermal treatment or cryogenic shock freezing and fine-dispersed grinding is used as an innovation. A new method for obtaining finely dispersed additives and health
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41

Boullemant, Amiel, Bernard Vigneault, Claude Fortin, and Peter G. C. Campbell. "Uptake of Neutral Metal Complexes by a Green Alga: Influence of pH and Humic Substances." Australian Journal of Chemistry 57, no. 10 (2004): 931. http://dx.doi.org/10.1071/ch04093.

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We have examined the influence of pH and a natural humic acid on the short-term uptake (<40 min) of a neutral, lipophilic metal complex by a unicellular freshwater alga, Pseudokirchneriella subcapitata. Cadmium diethyldithiocarbamate ([Cd(DDC)2]0) was used as a model lipophilic metal complex and Suwannee River Humic Acid (SRHA) was chosen as a representative aquatic humic acid (6.5 mg C L−1). Under the experimental conditions virtually all the Cd was expected to be present as the lipophilic complex ([Cd]T = 0.38 nM; [DDC] 1 μM; [Cd2+] <10−15 M; pH 7.0, 6.0, or 5.5). Uptake of [Cd(DDC)2]0
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Bates, Nicola. "Poisons affecting the cardiovascular system." Companion Animal 25, no. 8 (2020): 215–23. http://dx.doi.org/10.12968/coan.2020.0066.

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Cardiac and cardiovascular function can be affected by numerous substances, including overdose of drugs for cardiac and cardiovascular conditions, drugs used in the management of other diseases, over-the-counter medicines and supplements, foods and natural toxins such as plants. A common cause of tachycardia in dogs is exposure to salbutamol from piercing an asthma inhaler. Cardiac drugs such as beta-blockers and calcium-channel blockers can cause hypotension and disrupt cardiac rhythm. Although severe cases are not common in companion animals, management may be complex, requiring high dose in
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Bates, Nicola. "CPD article: Poisons affecting the cardiovascular system." Veterinary Nurse 11, no. 7 (2020): 310–19. http://dx.doi.org/10.12968/vetn.2020.11.7.310.

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Cardiac and cardiovascular function can be affected by numerous substances, including overdose of drugs for cardiac and cardiovascular conditions, drugs used in the management of other diseases, over-the-counter medicines and supplements, foods and natural toxins such as plants. A common cause of tachycardia in dogs is exposure to salbutamol from piercing an asthma inhaler. Cardiac drugs such as beta-blockers and calcium-channel blockers can cause hypotension and disrupt cardiac rhythm. Although severe cases are not common in companion animals, management may be complex, requiring high dose in
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44

Кобелева and S. Kobeleva. "Choice of Criteria for Ecological Assessment of Construction Technologies." Safety in Technosphere 2, no. 6 (2013): 29–32. http://dx.doi.org/10.12737/2159.

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The fuel-energy complex and the construction industry are ones of the main sources of environment pollution. The main man-made emissions have been analyzed, and calculations of buildings’ energy consumption have been presented in this paper. To assess the contribution of construction technologies in environmental issues it has been proposed the following criteria: total energy consumption; emissions of polluting substances in the biosphere; natural resources consumption.
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Bouyahya, Abdelhakim, Hamza Mechchate, Loubna Oumeslakht, et al. "The Role of Epigenetic Modifications in Human Cancers and the Use of Natural Compounds as Epidrugs: Mechanistic Pathways and Pharmacodynamic Actions." Biomolecules 12, no. 3 (2022): 367. http://dx.doi.org/10.3390/biom12030367.

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Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal cells. The mechanistic understanding of the pathways involved in tumor transformation has implicated a priori predominance of epigenetic perturbations and a posteriori genetic instability. In this work, we aimed to explain the mechanistic involvement of epigenetic pathways in the cancer process, as well as the abilities of natural bioactive compounds isolated from medicinal plants (flavonoids, phenolic acids, stilbenes, and ketones) to specifically target the epigenome of tumor cells. The molecular event
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46

Pilon, Alan Cesar, Marcelo Del Grande, Maíra R. S. Silvério, et al. "Combination of GC-MS Molecular Networking and Larvicidal Effect against Aedes aegypti for the Discovery of Bioactive Substances in Commercial Essential Oils." Molecules 27, no. 5 (2022): 1588. http://dx.doi.org/10.3390/molecules27051588.

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Dengue is a neglected disease, present mainly in tropical countries, with more than 5.2 million cases reported in 2019. Vector control remains the most effective protective measure against dengue and other arboviruses. Synthetic insecticides based on organophosphates, pyrethroids, carbamates, neonicotinoids and oxadiazines are unattractive due to their high degree of toxicity to humans, animals and the environment. Conversely, natural-product-based larvicides/insecticides, such as essential oils, present high efficiency, low environmental toxicity and can be easily scaled up for industrial pro
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47

Zhorov, G. А., L. L. Zakharova, and V. N. Obryvin. "BACKGROUND CONTENT OF TECHNOGENIC AND NATURAL RADIONUCLIDES IN DETOXIFYING AND BIOLOGICALLY ACTIVE SUBSTANCES." Problems of Veterinary Sanitation, Hygiene and Ecology 1, no. 2 (2021): 223–29. http://dx.doi.org/10.36871/vet.san.hyg.ecol.202102019.

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For correctly assess the effectiveness and safety of the use of sorption-detoxifying agents and feed additives intended for animals receiving feed with an excess content of toxicants, it is necessary to take into account the background levels of radionuclides, toxic elements, pesticides and other technogenic and natural pollutants in the studied substances. The need for such studies is due both to the existence of areas with a naturally elevated level of natural toxicants in the sources of raw materials for the production of additives and drugs, and to the increasing anthropogenic influence, a
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48

Silva-Carvalho, Ricardo, Fátima Baltazar, and Cristina Almeida-Aguiar. "Propolis: A Complex Natural Product with a Plethora of Biological Activities That Can Be Explored for Drug Development." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–29. http://dx.doi.org/10.1155/2015/206439.

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The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different plants, buds, and exudates in different geographic areas. Propolis has been attracting scientific attention since it has many biological and pharmacological properties, which are related to its chemical composition. Severalin vitroandin vivostudies have been performed to characterize and understand the d
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Проскурнін, О. А., Т. В. Божко, В. М. Жук, Б. М. Комариста та В. І. Бендюг. "ДОЦІЛЬНІСТЬ ВРАХУВАННЯ КОМПЛЕКСНИХ ПОКАЗНИКІВ ЯКОСТІ ПРИРОДНОЇ ВОДИ ПРИ НОРМУВАННІ СКИДАНЬ ЗАБРУДНЮЮЧИХ РЕЧОВИН ІЗ ЗВОРОТНИМИ ВОДАМИ У ВОДНІ ОБ'ЄКТИ". SCIENTIFIC BULLETIN OF CIVIL ENGINEERING 108, № 2 (2022): 79–84. http://dx.doi.org/10.29295/2311-7257-2022-108-2-79-84.

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The article is devoted to justifying the feasibility of taking into account complex indicators of natural water quality in the task of regulating the discharge of pollutants with waste waters to water bodies. The problem has scientific and legal aspects. The scientific aspect is the similarity of the harmful effect of various substances on living organisms. Attention is drawn to the fact that in the tasks of normalization of discharge of waste water, it is advisable to calculate the complex negative effect of substances according to the limiting signs of harmfulness (LSH). Concerning the legal
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Boullemant, Amiel, Jean-Pierre Gagné, Claude Fortin, and Peter G. C. Campbell. "Interactions of hydrophobic metal complexes and their constituents with aquatic humic substances." Environmental Chemistry 4, no. 5 (2007): 323. http://dx.doi.org/10.1071/en07046.

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Environmental context. Lipophilic metal complexes, because they can readily cross biological membranes, are especially bioavailable. However, in natural waters these complexes do not necessarily exist in a free state, i.e. they may bind to the organic matter (humic substances) that is present in natural waters. It follows that the in situ bioavailability of lipophilic metal complexes will tend to be less than that measured in simple laboratory experiments. Abstract. The ability of dissolved humic substances (HS: fulvic and humic acids) to complex cationic metals is well known, but their intera
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