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1

Andersson, Camilla. "Challenges of studying complex community health promotion programmes : experiences from Stockholm diabetes prevention programme /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-703-0/.

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2

Cambon, Linda. "Étude de la transférabilité des interventions de promotion de la santé dans une perspective de promotion des démarches "evidence based health promotion" : développement d'un outil d'analyse de la transférabilité des interventions." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0276/document.

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Contexte : Les interventions de promotion de la santé agissent sur l'ensemble des déterminants de la santé. Cette caractéristique en fait le levier nécessaire à la lutte contre les inégalités sociales de santé mais rendent ces dernières complexes à mettre en oeuvre, à évaluer et à transférer. Il y a un enjeu à développer en France la promotion de la santé fondée sur les preuves et donc à favoriser le transfert d'interventions. La question de la transférabilité, c'est-à-dire la mesure dans laquelle l'effet d'une intervention dans un contexte donné peut être atteint dans un autre contexte, devie
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3

Lee, Judith. "Melancholy, the muse and mental health promotion : an analysis of the complex relationship between mood disorder and creativity, developing a scientific model of mental health promotion." Thesis, University of Ulster, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428346.

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4

Trompette, Justine. "Complexité des interventions en santé publique et en promotion de la santé : exploration de son appréhension par les chercheurs et par les acteurs de terrain." Thesis, Université de Lorraine, 2017. http://www.theses.fr/2017LORR0335/document.

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Contexte – Les interventions de santé publique et plus particulièrement les interventions de promotion de la santé sont considérées comme « complexes ». Leur évaluation représente un défi tant pour les chercheurs – lorsqu’il s’agit de caractériser ce qui produit des effets – que pour les acteurs – lorsqu’il s’agit de transférer une intervention d’efficacité prouvée –, notamment en raison de la forte influence du contexte sur l’efficacité de ces interventions. Cette problématique de la complexité soulève plusieurs questions aussi bien conceptuelles qu’opérationnelles : comment les chercheurs et
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5

Edvardsson, Kristina, Anneli Ivarsson, Rickard Garvare, et al. "Improving child health promotion practices in multiple sectors : outcomes of the Swedish Salut Programme." Umeå universitet, Epidemiologi och global hälsa, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-60853.

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Background: To improve health in the population, public health interventions must be successfully implemented within organisations, requiring behaviour change in health service providers as well as in the target population group. Such behavioural change is seldom easily achieved. The purpose of this study was to examine the outcomes of a child health promotion programme (The Salut Programme) on professionals' self-reported health promotion practices, and to investigate perceived facilitators and barriers for programme implementation. Methods: A before-and-after design was used to measure progr
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6

Троян, Марія Юріївна, Мария Юрьевна Троян, Mariia Yuriivna Troian та Т. В. Якушко. "Перешкоди просування продукції молочної галузі України на ринку ЄС". Thesis, Сумський державний університет, 2014. http://essuir.sumdu.edu.ua/handle/123456789/47455.

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Агропромисловий комплекс є однією з провідних галузей спеціалізації України. Зокрема особливе місце займає молочна галузь, продукція якої користується популярністю як у межах країни, так і за кордоном.Виробництво молока є чи не єдиним рентабельним сільськогосподарським виробництвом Україні, його рентабельність у 2013 році склала по країні вцілому 13,4%, а по деяким регіонам більше 25%.
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7

Ілляшенко, Сергій Миколайович, Сергей Николаевич Ильяшенко, Serhii Mykolaiovych Illiashenko та І. В. Меркун. "Виставковий стенд як інструмент формування іміджу і просування ТОВ «Керамейя» і його продукції". Thesis, ФОП Ткачов О.О, 2016. http://essuir.sumdu.edu.ua/handle/123456789/46312.

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Виконано аналіз ефективності застосування стенда як елемента виставкової діяльності ТОВ "Керамейя".<br>Выполнен анализ эффективности применения стенда как элемента выставочной деятельности ООО "Керамейя".<br>The analysis of effectiveness of stand as an element of the exhibition activities of the "Kerameya" LTD.
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8

Siriaporn, Nuttanun. "Transport actif, santé et environnement (ASTHAIR) : une approche multidisciplinaire du changement de comportement, de l'engagement communautaire et de la pensée systémique pour promouvoir le transport actif." Electronic Thesis or Diss., Université Côte d'Azur, 2025. http://www.theses.fr/2025COAZ4005.

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Le manque d'activité physique (PA) et la pollution de l'air sont en croissance dans la plupart des populations mondiales (Sicard et al., 2023 ; Strain et al., 2024) et tout particulièrement parmi les groupes défavorisés (Hajat et al., 2015). Ces deux problématiques sont des facteurs majeurs qui participent à la croissance des maladies non-transmissibles (NCD). Ces dernières sont les causes principales de décès dans les pays à revenus élevés et elles représentent une menace grandissante dans les pays à faibles revenus (World Health Organization, 2024e). En mitigeant ces risques, il sera possibl
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9

Ілляшенко, Сергій Миколайович, Сергей Николаевич Ильяшенко, Serhii Mykolaiovych Illiashenko та ін. "Роль виставкової діяльності у просуванні промислового підприємства на ринку". Thesis, ФОП Вишемирський В.С, 2019. http://essuir.sumdu.edu.ua/handle/123456789/73204.

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Досліджено теоретичні засади управління виставковою діяльністю підприємств, на їх основі запропонована укрупнена блок-схема алгоритму управління виставковою діяльністю на промисловому підприємстві, розроблено послідовність і зміст процедур управління, а також їх інформаційне забезпечення. Спираючись на результати аналізу виставкової діяльності ТОВ «Керамейя» доведено її високу ефективність, що підтверджує адекватність авторського підходу до управління нею.<br>Исследованы теоретические основы управления выставочной деятельностью предприятий, на их основе предложена укрупненная блок-схема алгори
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10

Matyskiela, Mary E. "Substrate binding by the anaphase-promoting complex." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3378672.

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11

Oelschlägel, Tobias. "Meiosis-specific Regulation of the Anaphase-Promoting Complex." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2006. http://nbn-resolving.de/urn:nbn:de:swb:14-1143717017741-21454.

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Meiosis is a specialized cell cycle, which generates haploid gametes from diploid parental cells. During meiosis one round of cohesion establishment during premeiotic DNA replication mediates two rounds of chromosome segregation. During meiosis I homologous chromosomes separate, whereas sister chromatids segregate during the second meiotic division without an intervening round of DNA replication. Both rounds of chromosome segregation are triggered by an ubiquitin ligase called the Anaphase-Promoting Complex or Cyclosome (APC/C). APC/C-dependent destruction of securin/Pds1 is required to activa
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12

Torres, Matthew Phillip Borchers Christoph H. "Regulation of the anaphase-promoting complex by phosphorylation." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,936.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Dec. 18, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Biochemistry and Biophysics." Discipline: Biochemistry and Biophysics; Department/School: Medicine.
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13

Schreiber, Anne. "Structural studies of the anaphase promotinq complex/cyclosome." Thesis, University of London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539894.

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14

Oelschlägel, Tobias. "Meiosis-specific Regulation of the Anaphase-Promoting Complex." Doctoral thesis, Technische Universität Dresden, 2005. https://tud.qucosa.de/id/qucosa%3A24682.

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Meiosis is a specialized cell cycle, which generates haploid gametes from diploid parental cells. During meiosis one round of cohesion establishment during premeiotic DNA replication mediates two rounds of chromosome segregation. During meiosis I homologous chromosomes separate, whereas sister chromatids segregate during the second meiotic division without an intervening round of DNA replication. Both rounds of chromosome segregation are triggered by an ubiquitin ligase called the Anaphase-Promoting Complex or Cyclosome (APC/C). APC/C-dependent destruction of securin/Pds1 is required to activa
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15

Jörgensen, Pia-Marie. "Regulation of mitosis : molecular analysis of the anaphase-promoting complex /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4483-0/.

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16

Dial, John Michael Borchers Christoph H. "Inhibition of the Cdh1-dependent anaphase-promoting complex by Acm1." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,967.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Dec. 18, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Biochemistry & Biophysics." Discipline: Biochemistry and Biophysics; Department/School: Medicine.
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17

Passmore, Lori Anne. "Structural and functional studies of the anaphase promoting complex (APC)." Thesis, Institute of Cancer Research (University Of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406167.

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18

Van, Roessel Peter Johannes. "A neurobiological role for the anaphase-promoting complex in Drosophila." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619827.

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19

Foster, Jessica. "Investigating the relationship between UbcH10 and the anaphase promoting complex/cyclosome." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8024/.

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UbcH10 functions as an E2-conjugating enzyme for the Anaphase-Promoting Complex/Cyclosome (APC/C) E3-ubiquitin ligase, and helps to facilitate the APC/C-dependent ubiquitylation of substrates during mitosis and G1. UbcH10 is also a proto-oncogene product that is overexpressed in a number of human cancers. Despite its ability to promote APC/C ubiquitin ligase activity, and initiate tumourigenesis, very little is known about the UbcH10 interactome. Here we used immunoprecipitations-coupled to mass spectrometry to identify the UbcH10 interactome in HeLa and RPE-1 cells. Of those proteins identifi
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20

Yeung, Wai. "RNA interference-based screenings for anaphase-promoting complex/cyclosome regulatory phosphatases /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?BICH%202008%20YEUNG.

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21

Wu, George Tatung. "The role of anaphase-promoting complex in cellular differentiation and tumorigenesis /." Access full-text from WCMC, 2008. http://proquest.umi.com/pqdweb?did=1528351821&sid=7&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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Lopes, Mariana Paiva. "Estrutura e variabilidade do promotor do gene do fator de necrose tumoral humano (TNF)." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/7768.

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Submitted by Franciele Moreira (francielemoreyra@gmail.com) on 2017-09-13T17:35:41Z No. of bitstreams: 2 Dissertação - Mariana Paiva Lopes - 2014 .pdf: 2192084 bytes, checksum: e551c174d821b3b398247680a94c40cd (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-09-19T13:59:44Z (GMT) No. of bitstreams: 2 Dissertação - Mariana Paiva Lopes - 2014 .pdf: 2192084 bytes, checksum: e551c174d821b3b398247680a94c40cd (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>M
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Weisse, Sandrine. "Complexes cyclodextrines/esther de vitamine A : stabilisation, solubilisation et promotion de l'absorption cutanée." Paris 11, 2002. http://www.theses.fr/2002PA114817.

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Rodrigo, Brenni Monica C. "E2s act sequentially in the assembly of ubiquitin chains by the anaphase-promoting complex." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3378504.

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Pesin, Jillian Annice (Pesin-Fulop). "The developmental role and regulation of the Anaphase-Promoting Complex/Cyclosome in Drosophila meiosis." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/42399.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, February 2008.<br>Includes bibliographical references.<br>Meiosis is a modified cell cycle in which two round of chromosome segregation occur without an intervening DNA synthesis phase. As in mitosis, these cell divisions are driven in part by proteolysis mediated by the Anaphase-Promoting Complex/ Cyclosome (APC/C). During oogenesis of multicellular organisms, molecular control of meiosis has an added complexity because these divisions must be coordinated with the growth and development of the oocyte as well as its fert
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Tipton, Aaron R. "How to Assemble a Functional Mitotic Checkpoint Complex." University of Toledo / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1341597834.

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Towner, Laurence. "Investigating the tumour promoting roles of complement membrane attack complex using global gene expression analysis." Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/53361/.

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Activation of complement and its terminal pathway leads to the formation and insertion of the membrane attack complex (MAC) in the membranes of target cells. Complement is activated in tumours as is clear from the presence of complement activation products in cancer tissues. Over-expression of membrane bound complement regulators on tumour cells together with endogenous recovery mechanisms restricts complement activity and results in escape from lytic killing; nevertheless, sublytic MAC deposition is not without consequence. Sublytic MAC assembly on nucleated cells causes cell activation, secr
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Troccolo, Paul M. "Enhanced Animal Cloning: the Effects of Demecolcine on the Anaphase Promoting Complex in Mammalian Development." Digital WPI, 2007. https://digitalcommons.wpi.edu/etd-theses/37.

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The efficiency of somatic cell nuclear transfer has been improved slightly with the use of Demecolcine as a chemical enucleant. While the reasons for this improved efficiency remain unclear, it has been hypothesized that the Demecolcine assisted enucleation procedure is less exigent to vital cell processes within the oocyte including the Anaphase-Promoting Complex (APC) dependent ubiquitination of proteins. In order to test the effect of Demecolcine on the APC, the spatial localizations of Apc11, the catalytic core of the complex, and Cdc20, a main activator of the complex, were studied in d
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Ban, Kenneth. "Localized regulation of the anaphase-promoting complex by the Emi1/NuMA/Dynein-dynactin (END) network /." May be available electronically:, 2007. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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Towers, Russell. "Characterization of the interaction between the chicken anaemia virus protein apoptin and the anaphase-promoting complex." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=96967.

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The Chicken anaemia virus protein apoptin is able to induce apoptosis specifically in human transformed cells independently of p53 through a mechanism that remains to be elucidated. Current evidence suggests that apoptin acts through inhibition of the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase required for mitosis, by binding to the subunit APC1. In this study, apoptin was found to induce dissociation and degradation of the APC/C by associating with other subunits in addition to APC1 (APC2, APC3/Cdc27 and APC7). The APC1 binding location was localized to the C-terminu
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Havens, Courtney Guiheen. "Regulation of late G1/S phase transition and the anaphase promoting complex-Cdh1 by reactive oxygen species /." Diss., Connect to a 24 p. preview or request complete full text in PDF formate. Access restricted to UC campuses, 2006. http://wwwlib.umi.com/cr/ucsd/fullcit?p3236627.

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Minshall, Paul Edward. "Characterisation of novel functions of the anaphase promoting complex/cyclosome and its regulation through post-translational modification." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5694/.

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The Anaphase Promoting Complex/Cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase that regulates mitotic progression through targeting substrates for degradation by the 26S proteasome. In order to assess APC/C post-translational modification status, and identify novel APC/C substrates and regulators, a comprehensive analysis of the APC/C and APC/C-interacting proteins by mass spectrometry was undertaken. RNA polymerase I was identified as an APC/C-interacting complex, and the interaction was validated by reciprocal co-immunoprecipitation, GST pull-down and immunofluorescent confocal micr
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Bolte, Melanie. "Regulation of the anaphase promoting complex (APC-C) in the mitotic and meiotic cell cycle of Saccharomyces cerevisiae." Doctoral thesis, [S.l.] : [s.n.], 2004. http://webdoc.sub.gwdg.de/diss/2004/bolte/bolte.pdf.

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Mo, Min, and n/a. "Characterization of an Orf virus RING-H2 protein, B5L : a mimic of cellular anaphase promoting complex subunit 11." University of Otago. Department of Microbiology & Immunology, 2009. http://adt.otago.ac.nz./public/adt-NZDU20090220.085825.

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The anaphase promoting complex (APC/C) is an ubiquitin ligase that is an essential regulator of multiple steps in the cell cycle. The complex consists of at least 12 subunits with a catalytic core formed by a scaffold protein, APC2, and a RING-H2 protein, APC11. The Parapoxvirus, Orf virus (OV), encodes a RING-H2 protein, B5L, with clear sequence similarities to APC11. The disruption of APC/C function leads to pre-mature entry into S phase and a delayed M phase exit and, potentially, apoptosis. This investigation explored the functional significance of the similarity between B5L and APC11 and
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Whitfield, Zachary James. "A meiosis-specific form of the Anaphase Promoting Complex/Cyclosome regulates the oocyte-to-embryo transition in Drosophila." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/83781.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Cell cycle transitions during mitosis and meiosis must proceed in an irreversible manner. At the heart of this is the Anaphase Promoting Complex/Cyclosome (APC/C), an E3 ubiquitin ligase. The APC/C targets its substrates for degradation, and thus progresses the cell cycle irreversibly forward. Many substrates of the APC/C have been identified in mitosis, but how the APC/C regulates meiosis is less well understood. The Drosophila gen
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Lee, Jinho. "Le rôle du APC (Anaphase-Promoting Complex) au cours de la phase G2/M après dommage de l’ADN." Phd thesis, Grenoble 1, 2007. http://www.theses.fr/2007GRE10173.

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Les agents permettant de créer des dommages sur l’ADN sont principalement utilisés dans les traitements contre le cancer. L’activation de points de contrôle du cycle cellulaire après lésion de l’ADN entraîne un arrêt du cycle des cellules. De la connaissance des mécanismes moléculaires de l’arrêt du cycle cellulaire par ces points de contrôle dépend l’efficacité du traitement. Dans les cellules humaines, ces points de contrôle sont primordiaux puisque leur inactivation entraîne la carcinogenèse (génération de cancers). Après traitement par des agents chimiothérapiques et des rayons X, les cell
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Lee, Jinho. "Le rôle du APC (Anaphase-Promoting Complex) au cours de la phase G2/M après dommage de l'ADN." Phd thesis, Université Joseph Fourier (Grenoble), 2007. http://tel.archives-ouvertes.fr/tel-00247413.

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Les agents permettant de créer des dommages sur l'ADN sont principalement utilisés dans les traitements contre le cancer. L'activation de points de contrôle du cycle cellulaire après lésion de l'ADN entraîne un arrêt du cycle des cellules. De la connaissance des mécanismes moléculaires de l'arrêt du cycle cellulaire par ces points de contrôle dépend l'efficacité du traitement. Dans les cellules humaines, ces points de contrôle sont primordiaux puisque leur inactivation entraîne la carcinogenèse (génération de cancers). Après traitement par des agents chimiothérapiques et des rayons X, les cell
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Vicentin, Ana Paula Martins. "Conhecendo para intervir, em direção ao empoderamento pela atividade fisica no Complexo São Marcos, Campinas, SP." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/275486.

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Orientador: Aguinaldo Gonçalves<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Educação Fisica<br>Made available in DSpace on 2018-08-10T05:15:54Z (GMT). No. of bitstreams: 1 Vicentin_AnaPaulaMartins_M.pdf: 1859399 bytes, checksum: 60cea56bea2a2d7405e63d33ef7c3a38 (MD5) Previous issue date: 2008<br>Resumo: A expressão Promoção da Saúde tem sido utilizada com significados diversos. Desde 1986, com a Carta de Ottawa, pode ser entendida como o processo de capacitação da comunidade para atuação na melhoria da qualidade de vida e saúde. Com o amadurecimento das prátic
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Trusclair, Lisa Renee. "Motivating Allied Health Students to Successfully Complete Core Courses." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3640.

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This project study addressed the problem of a decline in retention of students at a local allied health college. The need for allied health professionals is projected to exceed the availability by 2020, so it is important to identify strategies to help allied health students succeed. The purpose of this case study was to explore perceptions of students and faculty about motivating factors and learning strategies that foster successful progression in allied health programs. Ryan and Deci's self-determination theory, focused on the relationship between motivation and success, served as the frame
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Argunhan, Bilge. "Interplay between Dbf4-dependent Cdc7 kinase and polo-like kinase unshackles mitotic recombination mechanisms by promoting synaptonemal complex disassembly." Thesis, University of Sussex, 2016. http://sro.sussex.ac.uk/id/eprint/59019/.

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Meiotic recombination is initiated by self-inflicted DNA breaks and primarily involves homologous chromosomes, whereas mitotic recombination involves sister chromatids. Whilst the mitotic recombinase Rad51 exists during meiosis, its activity is suppressed in favour of the meiosis-specific recombinase, Dmc1, thus establishing a meiosis-specific mode of homologous recombination (HR). A key contributor to the suppression of Rad51 activity is the synaptonemal complex (SC), a meiosis-specific chromosomal structure that adheres homologous chromosomes along their entire lengths. Here, in budding yeas
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Zich, Judith. "Analysis of Mph1 kinase and its substrates in spindle checkpoint signalling." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/8253.

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Accurate chromosome segregation is crucial as mis-segregation results in aneuploidy, which can lead to severe diseases such as cancer. The spindle checkpoint monitors sister-chromatid attachment and inhibits the onset of anaphase until all chromosomes are correctly bi-oriented on the mitotic spindle. The spindle checkpoint machinery of S.pombe is composed of many proteins, one of which is the kinase Mph1 (Mps1p-like pombe homolog). It previously has been shown that Mph1 is essential for the spindle checkpoint but not whether this is due to its kinase activity. In this study we determined the r
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Quispe, Cabrera Patricia Adela María. "Complejo promotor de la cultura afroperuana en el Distrito de El Carmen, Chincha, Ica." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/624133.

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Este proyecto tiene como objetivo principal lograr un sentido de pertenencia del proyecto arquitectónico con el lugar, la población y los usuarios. Además de crear una relación directa o indirecta con la cultura afroperuana, a través de la reinterpretación de su arquitectura. Por lo tanto, se alude a la arquitectura vernácula del sitio y la costa peruana que se refiere a las características de las edificaciones del sitio en aspectos formales y funcionales.<br>This project has the main objective to achieve a sense of belonging of the architectural project with the place, the population and the
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Hammerschmidt, Karina Silveira de Almeida. "Gerontotecnologias para o ensino educativo direcionadas ao idoso: cuidado de enfermagem complexo." reponame:Repositório Institucional da FURG, 2011. http://repositorio.furg.br/handle/1/2942.

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Tese(doutorado) - Universidade Federal do Rio Grande, Programa de Pós-Graduação em Enfermagem, Escola de Enfermagem, 2011.<br>Submitted by eloisa silva (eloisa1_silva@yahoo.com.br) on 2012-12-04T14:31:38Z No. of bitstreams: 1 karina.pdf: 3490433 bytes, checksum: e4784c271cd64ffc8fb1aa6cdb12eb7b (MD5)<br>Approved for entry into archive by Bruna Vieira(bruninha_vieira@ibest.com.br) on 2012-12-06T03:08:44Z (GMT) No. of bitstreams: 1 karina.pdf: 3490433 bytes, checksum: e4784c271cd64ffc8fb1aa6cdb12eb7b (MD5)<br>Made available in DSpace on 2012-12-06T03:08:44Z (GMT). No. of bitstreams: 1 karina.pdf
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Weirich, Alexandra. "Initiating the Spindle Assembly Checkpoint Signal: Checkpoint Protein Mad1 Associates with Outer Kinetochore Protein Ndc80 in Budding Yeast." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24248.

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The spindle assembly checkpoint (SAC) is an evolutionarily conserved mechanism that delays the initiation of anaphase by inhibiting the Anaphase Promoting Complex (APC) until all kinetochores have achieved bipolar attachment on the mitotic spindle. Mad1-3, Bub1, and Bub3, components of the SAC, are conserved from yeast to humans. These proteins localize to unattached kinetochores, though it is unknown with which kinetochore proteins they interact and how these interactions transduce information about microtubule attachement. Here, purification of the checkpoint proteins from Saccharomyces ce
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Тимохіна, Яна Олександрівна, Яна Александровна Тимохина та Yana Oleksandrivna Tymokhina. "Управління комплексом маркетингових комунікацій промислового підприємства". Thesis, СумДУ, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41863.

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Дисертація присвячена вдосконаленню управління маркетинговими комунікаціями промислового підприємства. У дисертаційній роботі запропоновано та обґрунтовано науково-методичний підхід до формування комплексу просування промислового підприємства. Запропоновано визначення поняття «синтезовані маркетингові комунікації» та класифікацію інструментів маркетингових комунікацій. Розвинено методичний підхід до планування маркетингової комунікаційної діяльності промислових підприємств за рівнями управління з використанням синтезованого інструментарію просування. Сформовано та обґрунтовано теоретико-методи
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Sobon, Michelle. "A Preliminary Perspective for Identifying Resilience and Promoting Growth Among Survivors of Sex Trafficking." Wright State University Professional Psychology Program / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wsupsych1407280532.

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Schwartz, Laura Link. "HnRNP E1 Protects Chromosomal Stability Through Post-Transcriptional Regulation of Cdc27 Expression." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1445519325.

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Wendt, Kerstin Sybille. "Zwei Untereinheiten aus Proteinkomplexen die Kristallstruktur der APC10-Untereinheit des humanen Anaphase-promoting-Complex und die Kristallstruktur der Carboxytransferase-Untereinheit der Glutaconyl-CoA-Decarboxylase aus Acidaminococcus fermentans /." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965479730.

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Zhang, Suyang. "Mechanism of APC/C activation and substrate specificity in mitosis." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/275479.

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In eukaryotes, cell proliferation and cell cycle transitions are strictly controlled by the anaphase-promoting complex/cyclosome (APC/C). The APC/C is an E3 ubiquitin ligase that regulates chromatid segregation at the metaphase to anaphase transition, exit from mitosis and the establishment and maintenance of G1. The APC/C’s catalytic activity and substrate specificity are controlled by its interactions with two coactivators, Cdc20 and Cdh1. In contrast to Cdh1, APC/C activation by Cdc20 during mitosis requires hyper-phosphorylation of APC/C subunits by cyclin-dependent kinase (Cdk) and polo k
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Unruh, Janie. "Adventist Affiliation and Type 2 Diabetes Pre- and Post-Complete Health Improvement Program (CHIP)." Thesis, Walden University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10164834.

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<p> Adventists following a plant-based diet have half the prevalence and incidence of type 2 diabetes than nonvegetarian Adventists. This study used a quantitative, correlational study design to assess if there was a significant difference in type 2 diabetes prevalence rate between Adventists and non-Adventists preprogram, and if there were significant differences in biometrics between Adventists and non-Adventists with diabetes pre- and post-Complete Health Improvement Program (CHIP). This study incorporated the social ecological model for its conceptual framework and examined pre- and postp
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