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1

Lawson, Erin F., and Joel P. Castellanos, eds. Complex Regional Pain Syndrome. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-75373-3.

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2

Juris, Elena. Positive options for complex regional pain syndrome (CRPS): Self-help and treatment. Hunter House, an imprint of Turner Publishing Company, 2014.

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3

Pidcock, Frank S. Complex Regional Pain Syndrome. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0121.

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Complex Regional Pain Syndrome (CRPS) is a chronic disorder that affects adults and children. It is extremely challenging to manage and results in dysfunctional patterns of behavior that have long-reaching effects on the patient and their families. New insights into the neurobiology of this condition have improved the understanding of mechanisms that alter nocioceptive perception and remodel neural circuitry in the brain and spinal cord. Traditional interventions for treating pain have little if any long-term effects. An interdisciplinary program addressing “bio-psycho-social factors” that inc
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4

Walters, Jenna L. Complex Regional Pain Syndrome. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0025.

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Complex regional pain syndrome (CRPS) is a neuropathic pain condition classified as type 1 and type 2. The two classifications are distinguished by the presence of documented nerve injury in CRPS type 2. The symptoms of CRPS, including cold, blue, and painful extremities, are believed to occur from vasoconstriction caused by sympathetic dysfunction. Treatment in CRPS focuses on targeting neuropathic and sympathetically maintained pain. Traditional antineuropathic pain medications include membrane stabilizers and serotonin and norepinephrine reuptake inhibitors. Corticosteroids and nonsteroidal
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5

Atkins, Roger M. Complex regional pain syndrome. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.0011.

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♦ Complex regional pain syndrome (CRPS) is a disabling chronic pain condition of unknown aetiology♦ Traditionally it was thought to be rare; however, prospective studies demonstrate it to be common following both trauma and operative procedures involving the upper and lower limbs♦ The condition is usually self-limiting over a maximum period of 2 years, although minor abnormalities may remain♦ In a minority of cases it does not resolve and is responsible for severe chronic disability♦ Treatment is aimed at functional restoration of limb function supported by pharmacological intervention.
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6

1954-, Harden R. Norman, and Reflex Sympathetic Dystrophy Syndrome Association., eds. Complex regional pain syndrome: Treatment guidelines. RSDSA Press, 2006.

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7

Riley, Bobbie, and Navil Sethna. Pediatric Complex Regional Pain Syndrome Type 1. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0054.

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Complex regional pain syndrome type 1 (CRPS-1) is a condition that affects adolescents and children under the age of 7. It usually follows minor injury and rarely occurs spontaneously. The pain is usually out of proportion to the inciting injury. Pain, allodynia, and/or hyperalgesia are severe enough to inhibit use of the affected limb. Delay in diagnosis and self and/or iatrogenic immobilization of the affected limb may lead to worsening pain, skin hypersensitivity and discoloration, swelling, and vasomotor and dystrophic abnormalities. The diagnosis of CRPS-1 and 2 is based on symptoms. Ther
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8

Scott, Naomi. The epidemiology of complex regional pain syndrome. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0062.

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The landmark paper discussed in this chapter describes a retrospective study examining the epidemiology of complex regional pain syndrome in the Dutch general population. The researchers accessed patient data by means of the Integrated Primary Care Information project, which provided a large representative sample of the general population inclusive of all ages. They found an incidence of 26.2 per 100,000 person-years from a source population of 190,902 people. In those patients diagnosed by a specialist, three contemporaneous diagnostic criteria were applied, one of which was that of the Inter
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9

Monico, Caro. Complex Regional Pain Syndrome for Ambulatory Surgery. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0055.

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Complex regional pain syndrome (CRPS) is a disease of the nervous system characterized by pain localized in an extremity. This pain is typically out of proportion to the inciting event and is accompanied by sensory disturbances, as well as motor, vasomotor, and sudomotor signs and symptoms. CRPS is a challenging clinical presentation and diagnosis. The etiology of this previously rare condition in children, is typically post-traumatic. It’s management requires a biopsychosocial approach. The principal modality that will improve pain and function in children with CRPS is physical therapy togeth
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10

Hooshmand, Hooshang M. D. Complex Regional Pain Syndrome: Diagnosis and Therapy. 2nd ed. Crc Pr I Llc, 2005.

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11

Nader, Nader D., and Ognjen Visnjevac. Complex Regional Pain Syndrome: Past, Present and Future. Nova Science Publishers, Incorporated, 2015.

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12

Martin, Douglas W., James B. Talmage, and Robert J. Barth. Complex Regional Pain Syndrome - What is the Evidence? Martin Occupational Medicine, PC, 2015.

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13

Lauder, Gillian R. Complex Regional Pain Syndrome in the Emergency Department. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0061.

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Acute exacerbation of an ongoing chronic pain can be a diagnostic and clinical dilemma. Chronic pain in children requires an interdisciplinary approach to assessment and treatment. Further, the child must commit to taking an active role in therapy. When this approach is not working, or there is an acute trauma to the affected region, children with chronic pain may present to the emergency department with extreme pain. Acute care health professionals may find themselves unable to modify the pain intensity with standard analgesic medications. The analgesic approach requires careful clinical mana
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14

(Editor), R. Norman Harden, Ralf Baron (Editor), and Wilfrid Janig (Editor), eds. Complex Regional Pain Syndrome (Progress in Pain Research and Management, V. 22). IASP Press, 2001.

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15

Complex Regional Pain Syndrome (CRPS) explained: For teenagers, by teenagers. Xlibris Corporation, 2010.

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16

Complex Regional Pain Syndrome (CRPS) explained: For teenagers, by teenagers. Xlibris Corporation, 2010.

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17

Stogicza, Agnes, Bartha Peter Tohotom, Edit Racz, Andrea Trescot, and Alan Berkman. Complex Regional Pain Syndrome of the Upper and Lower Extremity. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0011.

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Complex regional pain syndrome (CRPS) is a chronic debilitating pain condition of the extremities; it can affect, less commonly, other areas of the body (face, pelvis, abdomen). Its early presentation—pain disproportionate to the injury, skin temperature changes, hyperalgesia, allodynia—is often not recognized, delaying treatment. In later phases, with sympathetic nervous system involvement, it presents with skin and muscle atrophy, hair loss, allodynia, loss of function, and decreased range of motion. In severe cases, it can spread from one area to the other. Imaging findings (X-ray, MRI, bon
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18

National Institutes of Health (U.S.) and National Institute of Neurological Disorders and Stroke (U.S.), eds. Complex regional pain syndrome: Also called reflex sympathetic dystrophy syndrome. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 2003.

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19

Publications, ICON Health. Complex Regional Pain Syndrome - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References. ICON Health Publications, 2004.

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20

CRPS: Current Diagnosis And Therapy (Progress in Pain Research and Management, Volume 32). IASP Press, 2004.

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21

J, Koopman William, Boulware Dennis W, and Heudebert Gustavo R, eds. Clinical primer of rheumatology. Lippincott Williams & Wilkins, 2003.

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22

Koopman, William J., Dennis W. Boulware, and Gustavo Heudebert. Clinical Primer of Rheumatology. Lippincott Williams & Wilkins, 2003.

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23

Khursheed, Faraz, and Marc O. Maybauer. Neuropathic Pain. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0012.

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Neuropathic pain is a common condition that arises from injury anywhere along the somatosensory axis. Although the presentation may vary based on mechanisms and locations of injury, most patients have characteristic burning, shocklike, lancinating pain, most often in the distribution of peripheral and spinal nerves or distal extremities. Various peripheral and central processes aggravate pain through abnormal impulse generation, modulation, and processing. Common conditions include complex regional pain syndrome, diabetic neuropathy, postherpetic neuralgia, spondylotic radiculopathy, and centr
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24

Emmanuel, Johan. Trauma pain and procedural pain: prevention of chronic pain following acute trauma. Edited by Brigitta Brandner. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199234721.003.0008.

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Opioid analgesics should be used with extreme cautions in the self-ventilating head injured patient. Gastric emptying ceases after trauma. This will limit the efficacy of oral analgesics. Epidural analgesia has been shown to be an independent predictor of decreased morbidity and mortality in thoracic trauma. Femoral nerve block is as effective as intravenous morphine in femoral shaft fractures. Short-term non-steroidal anti-inflammatory drug use has no proven deleterious effects in humans, and should be part of multimodal management. Trauma is a risk factor for complex regional pain syndrome.
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25

Candido, Kenneth D., and Teresa M. Kusper. Sympathetic Pain Syndromes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190626761.003.0013.

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This chapter is a brief overview of the major sympathetic pain syndromes and their clinical characteristics, treatment, and preventative measures. It offers a concise overview of distinguishing characteristics, pathogenetic mechanisms, available treatment options for major sympathetic pain syndromes, and in-depth discussion pertaining to complex regional pain syndrome (CRPS) and the influence of specific surgical procedures on the development of this syndrome. Risk factors and pathogenetic mechanisms related to the emergence of CRPS after orthopedic and spine surgeries have been analyzed, as w
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26

News, PM Medical Health. 21st Century Complete Medical Guide to Complex Regional Pain Syndrome (CRPS) and Reflex Sympathetic Dystrophy, Authoritative Government Documents, Clinical ... for Patients and Physicians (CD-ROM). Progressive Management, 2004.

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27

McCabe, Candy, Richard Haigh, Helen Cohen, and Sarah Hewlett. Pain and fatigue. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0012.

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Pain and fatigue are the prominent problems for those with a rheumatic disease, and are often underestimated by clinicians. Symptoms may fluctuate in quality and intensity over time and commonly will vary over the course of a day. For pain, clinical signs and symptoms will be dependent on the source of the pain and whether causative underlying pathology is identifiable or not. Fatigue may range from mild effects to total exhaustion and may include cognitive and emotional elements, with a complex, probably multicausal, pathway. Theoretical knowledge of potential mechanistic pathways for pain an
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28

McCabe, Candy, Richard Haigh, Helen Cohen, and Sarah Hewlett. Pain and fatigue. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199642489.003.0012_update_001.

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Pain and fatigue are the prominent problems for those with a rheumatic disease, and are often underestimated by clinicians. Symptoms may fluctuate in quality and intensity over time and commonly will vary over the course of a day. For pain, clinical signs and symptoms will be dependent on the source of the pain and whether causative underlying pathology is identifiable or not. Fatigue may range from mild effects to total exhaustion and may include cognitive and emotional elements, with a complex, probably multicausal, pathway. Theoretical knowledge of potential mechanistic pathways for pain an
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29

Shah, Chirag D., and Maunak V. Rana. Advances in Dorsal Column Stimulation. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190626761.003.0017.

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Spinal cord stimulation (SCS) has been a long established therapy for various pain conditions including low back pain, failed back surgery syndrome, complex regional pain syndrome, and other neuropathic and nociceptive pain states. Since the first report of SCS in 1967 by Shealy, advances have occurred in the technology used to achieve clinical analgesia. Developments in both the hardware and software involved have led to significant improvements in functional specificity, as seen in dorsal root ganglion stimulation, along with increasing breadth and depth of the field of neuromodulation. The
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30

Kastler, Adrian, and Bruno Kastler. Cervical Sympathetic Block and Neurolysis: Computed Tomography. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0029.

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The stellate ganglion blockade technique is used to treat complex regional pain syndrome (CRPS). It is now well established that stellate blockades should be performed under imaging guidance. It has been suggested that alcohol may bring longer lasting relief in cases of severe intractable cancer-related pain arising from regional neoplasms invading the stellate ganglion, but frequent onset of Horner’s syndrome can outweigh the technique’s efficacy. Radiofrequency neurolysis (RFN) has become a common procedure in the management of chronic neuropathic pain. This chapter reviews indications of st
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31

Gofeld, Michael. Lumbar Transforaminal and Nerve Root Injections: Ultrasound. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0017.

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Ultrasound (US) guidance has gained recognition in the field of regional anesthesia mainly because of its definite advantage of visually localizing the desired target and also due to perceived benefits of safety, accuracy, and efficiency when peripheral nerve blocks are performed. On the contrary, ultrasonography of the spinal structures may be challenging because of depth, bony acoustic shadowing, and complex three-dimensional anatomy. Nevertheless, US allows satisfactory imaging of the posterior elements of spine column and paraspinal soft tissues. This makes US applicable and practical in t
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32

Mee, Sarah, and Zoe Clift. Hand Therapy. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757689.003.0002.

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Rehabilitation is a multidisciplinary, patient-centred, evidence-based process to promote healing, restore function, and promote independence. The physical and psychological and social consequences of the hand condition or injury have to be considered. Mobilization can be active or passive, supplemented by accessory movements and proprioceptive rehabilitation. Splinting may be static, serial static, static progressive, dynamic. Many materials are available. Oedema may be acute or chronic; it is treated with elevation, active movement, retrograde massage, compression, kinesiotaping, cold therap
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33

Anitescu, Magdalena, and Chirag Shah. The Vasovagal Reflex and Neuraxial Techniques. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0042.

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Syncope, or the transient loss of consciousness, is one of the leading causes of emergency department visits. Syncope can be neurally mediated, orthostatic, cardiac, or cerebrovascular. Neurally mediated vasovagal syncope is the most frequent form. Diagnostic modalities are tilt- table testing and implantable loop recorders. Therapeutic options usually begin with supportive measures, such as a fluid bolus or changing patient positioning, but complex cases may require vasoactive agents or placement of a pacemaker. In many situations patients who present to the operating room for various surgeri
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34

Suttmeier, Bruce. Eating amid Affluence. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190240400.003.0015.

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This chapter investigates the tensions between the pleasures and discomforts of indulgence in the 1960s and 1970s, an era of growing affluence and consumption, through the work of writer Kaikō Takeshi (1930–1989), who frequently waxed rhapsodically and nostalgically about his favorite foods in essays and novels. In his satiric 1972 serial A New Star, a middle-aged bureaucrat is ordered to literally eat his ministry’s budget surplus through lavish meals and regional excursions to consume local delicacies. The chapter observes that, while the novel can be read as a critique of consumption and go
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