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Journal articles on the topic 'Complex syndrome hypertension'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Mishchuk, N. E. "Nocturnal hypertension syndrome in combination with orthostatic hypotension: a complex scenario in the treatment of hypertension." Medicine of Ukraine, no. 4(250) (June 16, 2021): 35–40. http://dx.doi.org/10.37987/1997-9894.2021.4(250).238122.

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One of the most difficult scenarios in the treatment of hypertension is the syndrome of neurogenic orthostatic hypotension - hypertension in the supine position.Despite the large number of observations, publications and even a number of randomized studies, this syndrome remains poorly known and often remains unrecognized. In this regard, in 2017, the recommendations of leading experts in the United States and Canada on screening, diagnosis and treatment of neurogenic orthostatic hypertension and associated hypertension in the supine position were published.The principles and features of the di

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2

Kamalov, I. I. "Radiological features of hypertension-hydrocephalus syndrome." Kazan medical journal 67, no. 4 (1986): 287–89. http://dx.doi.org/10.17816/kazmj70529.

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The aim of this work was to differentiate the signs of hypertension and hydrocephalus, analyze and systematize them. We carried out complex radiological study of 97 patients (67 males and 30 females) with hypertension and hydrocephalus syndrome aged 25-30 years old with the determination of pressure in the liquor system. Observations showed that hypertension (increase of cerebrospinal pressure) in 17 patients proceeded without hydrocephalus.

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Kohli, Utkarsh. "Shone’s complex in a patient with chromosome 9q34.3 deletion (Kleefstra syndrome)." Cardiology in the Young 29, no. 2 (2018): 249–51. http://dx.doi.org/10.1017/s104795111800210x.

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AbstractKleefstra syndrome (chromosome 9q34.3 deletion) is a rare genetic disorder with less than 110 patients reported till date. We report a 4-month-old Caucasian girl with Kleefstra syndrome and Shone’s complex, an association which has not been previously reported. Surgical planning for patients with Kleefstra syndrome and complex CHD can pose challenges due to an uncertain natural history and a risk of post-operative pulmonary hypertension.

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Ignatenko, Grigory A., Ilya S. Grekov, Marina V. Grushina, and Anna V. Dubovyk. "A complex case of diagnosis of Conn’s syndrome." I.P. Pavlov Russian Medical Biological Herald 28, no. 1 (2020): 67–72. http://dx.doi.org/10.23888/pavlovj202028167-72.

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The primary hyperaldosteronism also known as Conns syndrome, is a rarely diagnosed disease that commonly runs under a mask of ischemic heart disease and the primary arteria hypertension (AH). Nevertheless, the incidence of the given pathology among all patients with AH makes almost 17%. On the other hand, the absence of specific clinical manifestations of the disease makes its timely and correct diagnosis difficult which is fraught with serious complications. In the article a clinical case of Conns syndrome and peculiarities of its diagnosis are described.

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Lozhkina, N. G., and A. N. Spiridonov. "Clinical case: early connection of valsartan/sacubitril in the treatment of hypertension." Kardiologiia 62, no. 5 (2022): 72–74. http://dx.doi.org/10.18087/cardio.2022.5.n1977.

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Metabolic syndrome is a disease the World Health Organization has called a new pandemic of the 21st century. Arterial hypertension is one of the criteria for this diagnosis and a determinant of damage to major target organs. The present clinical case demonstrates an experience of treatment of arterial hypertension associated with metabolic syndrome with a valsartan/sacubitril molecular complex.

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Akhundova, Maleyka, and Sabina Majidova. "HEERFORDT-WALDENSTRÖM SYNDROME (CLINICAL CASE)." Azerbaijan Journal of Ophthalmology, no. 2025/17/01/52 (April 8, 2025): 71–79. https://doi.org/10.71110/ajo791020251701527179.

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The article presents a clinical case of Heerfordt-Waldenström syndrome of patient A.Sh., born in 1972, who was undergoing inpatient treatment at the National Ophthalmology Centre named after Academician Zarifa Aliyeva. This syndrome manifested itself as anterior uveitis, facial nerve paralysis and of bilateral parotitis in anamnesis. Based on specific and ophthalmological examination, the following diagnosis was made: “Sarcoidosis, Heerfordt-Waldenström syndrome, uveitis, uveitic ocular hypertension of the right eye”. Appropriate complex therapy was carried out and a positive result was obtain

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Paykova, Alexandra S., Michail V. Alexandrov та Svetlana E. Ushakova. "The Еffectiveness of Stabilometrical Training in the Complex of Rehabilitation Measures in Elderly and Senile Patients with Arterial Hypertension". Bulletin of Rehabilitation Medicine 20, № 3 (2021): 53–58. http://dx.doi.org/10.38025/2078-1962-2021-20-3-53-58.

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The treatment and rehabilitation of elderly patients with hypertension is often hampered by their existing geriatric syndromes of senileasthenia and the risk of falls. Stabilometric balance training will allow to maintain the level of physical functioning and supporting theautonomy of this category of patients. Aim. To assess the possibilities of using stabilometric training with biofeedback to correct the risk of falls in patients aged 63 and olderwith arterial hypertension. Material and methods. On the basis of the geriatric department of the Regional Budgetary Institution of Health «Ivanovo

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Corredor-Orlandelli, David, Camila Borda, Juan Sebastian Sierra, and Daniel Gerardo Fernández-Ávila. "Multiple-autoimmune syndrome causing interstitial lung disease in the presence of pulmonary hypertension and Erasmus syndrome." Rheumatology (Bulgaria) 31, no. 4 (2024): 123–28. http://dx.doi.org/10.35465/31.4.2023.pp123-128.

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Connective tissue diseases constitute a group of inflammatory disorders that can concurrently affect multiple organs. Pulmonary manifestations of connective tissue diseases include interstitial lung disease, pulmonary hypertension, pleural diseases, and airway compromise. Both interstitial lung disease and pulmonary arterial hypertension have high morbidity and mortality in these patients. Interstitial lung disease affects 40 % - 50 % of patients with connective tissue diseases, predominantly systemic sclerosis, rheumatoid arthritis, and inflammatory myopathies. Parenchymal compromise is heter

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Ng, Wei Wei, and Shanty Velaiutham. "CARNEY COMPLEX." Journal of the ASEAN Federation of Endocrine Societies 39, S1 (2024): 22–23. https://doi.org/10.15605/jafes.039.s1.032.

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INTRODUCTION/BACKGROUND Carney complex (CNC) is a rare multiple endocrine neoplasia characterized by spotty skin pigmentation, myxomas and endocrine overactivity. We report a case of a young female with multiple typical manifestations of CNC over the past 12 years, including bilateral primary pigmented nodular adrenocortical disease, bilateral breast ductal adenoma, cardiac myxoma and thyroid nodule. CASEThis female first presented at age 28 for secondary amenorrhea, weight gain and uncontrolled hypertension. She had pigmentation over her lips and features of Cushing syndrome, such as facial p

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De Laura, D., V. Lavolpe, D. Rutigliano, et al. "P392 POST–THROMBOEMBOLIC PULMONARY HYPERTENSION: A COMPLEX CASE." European Heart Journal Supplements 25, Supplement_D (2023): D198. http://dx.doi.org/10.1093/eurheartjsupp/suad111.463.

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Abstract Introduction Patients with post–thromboembolic pulmonary hypertension (CTEPH) achieve functional recovery after pulmonary endarterectomy (PEA). 40% of them are inoperable (1,2). Clinical case 66–year–old man admitted in 2012 to our ward for dyspnea on exertion and high echocardiographic probability of pulmonary hypertension (PI). Medical history: smoking; thalassemia trait; COPD; splenectomy at 13; diagnosis of chronic myeloproliferative syndrome. BP: 120/70 mmHg. NYHA class III. Blood tests: Hb: 9.4 g/dl; MCV: 70; HCT: 30%; PLT: 511; WBC: 14.84 (Mo 13%).NT–pro BNP:933. Autoantibodies

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FO, Aranuwa. "MACHINE LEARNING TECHNIQUE FOR EARLY PREDICTION OF HYPERTENSION." International Journal of Engineering Applied Sciences and Technology 7, no. 5 (2022): 165–72. http://dx.doi.org/10.33564/ijeast.2022.v07i05.027.

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Machine Learning (ML) has proved to be an invaluable tool in medical research today. It is a branch of artificial intelligence that has the ability to learn from complex data, identify patterns and make decisions with minimal or without human intervention. Efforts in this work is focused at developing an intelligent model for early prediction of hypertension because of the complexity associated with the pattern identification of the syndrome. The study acquired data pertaining to the syndrome from selected healthcare centres in the South West region of Nigeria, one of the largest city in Afric

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Blöcher, R., C. Lamers, S. K. Wittmann, et al. "Design and synthesis of fused soluble epoxide hydrolase/peroxisome proliferator-activated receptor modulators." MedChemComm 7, no. 6 (2016): 1209–16. http://dx.doi.org/10.1039/c6md00042h.

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Arbuzova, M. S. "Experimental portal hypertension and portocaval anastomosis." Kazan medical journal 43, no. 3 (2021): 30–33. http://dx.doi.org/10.17816/kazmj83662.

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The problem of the pathogenesis and treatment of portal hypertension and cirrhosis of the liver is one of the most complex and difficult chapters of modern medicine. The difficulty lies both in the variety of etiological and pathogenetic features of this syndrome, and in the low effectiveness of conservative and surgical methods of treatment.

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Jang, Hyunseok, Naa Lee, Euisung Jeong, et al. "Abdominal compartment syndrome in critically ill patients." Acute and Critical Care 38, no. 4 (2023): 399–408. http://dx.doi.org/10.4266/acc.2023.01263.

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Intra-abdominal hypertension can have severe consequences, including abdominal compartment syndrome, which can contribute to multi-organ failure. An increase in intra-abdominal hypertension is influenced by factors such as diminished abdominal wall compliance, increased intraluminal content, and certain systemic conditions. Regular measurement of intra-abdominal pressure is essential, and particular attention must be paid to patient positioning. Nonsurgical treatments, such as decompression of intraluminal content using a nasogastric tube, percutaneous drainage, and fluid balance optimization,

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Kumar, Ravi, Deepak Kumar, Vipin Garg, and Sayed Salman ali. "Ayurvedic treatment of polycystic ovary syndrome (PCOS)." Southeast Asian Journal of Health Professional 4, no. 1 (2022): 6–9. http://dx.doi.org/10.18231/j.sajhp.2021.002.

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PCOS is a complex endocrine disorder with a wide range of symptoms that affects around one in every 15 women throughout the world. Metoligoovulation or anovulation, clinical or biochemical evidence of hyperandrogenism, and polycystic ovary shape are all diagnostic criteria for polycystic ovarian syndrome. Women with PCOS are more likely to develop metabolic abnormalities, hypertension, and cardiovascular disease. Using the databases Pubmed and Scielo, the goal of this work was to provide a review of papers pertinent to polycystic ovaries, including causation, symptoms, diagnostic, and treatmen

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Yang, Ying, Yong Ye, Huibo Wang, et al. "Malignant hypertension in a patient with Turner syndrome: A case report." Medicine 103, no. 31 (2024): e39128. http://dx.doi.org/10.1097/md.0000000000039128.

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Rationale: Turner syndrome is characterized by complete or partial loss of the second sex chromosome. In patients with Turner syndrome, hypertension is well described. However, the literature regarding malignant hypertension is scarce. Therefore, an accurate and timely diagnosis and treatment are important. Patient concerns: A 13-year-old female with Turner syndrome presented to the emergency department with malignant hypertension, headache, spraying vomiting, convulsion, and loss of consciousness. Considering her medical history, symptoms, and auxiliary examination, secondary hypertension (pr

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Suryowati, Trini, Fajar Lamhot Gultom, and Ester Grace Nikti Muntu. "Impact of Hypertension on Chronic Kidney Disease Patients." Journal of Drug Delivery and Therapeutics 12, no. 4 (2022): 125–32. http://dx.doi.org/10.22270/jddt.v12i4.5466.

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Hypertension is a progressive cardiovascular syndrome arising from complex and interrelated etiologies, characterized by an increase in systolic blood pressure higher than or equal to 140 mmHg or diastolic blood pressure higher than or equal to 90 mmHg. Hypertension is one of the main risk factors for chronic kidney disease. This research aims to know the impact of hypertension on chronic kidney disease patients in UKI General Hospital from 2019 – to 2020. The design of this research was retrospective. The sample used was 58 patients following inclusion criteria. The instruments used are medic

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Mrozek, Ségolène, Laurent Lonjaret, Aude Jaffre, et al. "Reversible Cerebral Vasoconstriction Syndrome with Intracranial Hypertension: Should Decompressive Craniectomy Be Considered." Case Reports in Neurology 9, no. 1 (2017): 6–11. http://dx.doi.org/10.1159/000455090.

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Background: Reversible cerebral vasoconstriction syndrome (RCVS) is a rare cause of intracerebral hemorrhage (ICH) causing intracranial hypertension. Methods: Case report. Results: We report a case of RCVS-related ICH leading to refractory intracranial hypertension. A decompressive craniectomy was performed to control intracranial pressure. We discuss here the management of RCVS with intracranial hypertension. Decompressive craniectomy was preformed to avoid the risky option of high cerebral perfusion pressure management with the risk of bleeding, hemorrhagic complications, and high doses of n

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Nicholson, George T., Michael S. Kelleman, Caridad M. De la Uz, Ricardo H. Pignatelli, Nancy A. Ayres, and Christopher J. Petit. "Late outcomes in children with Shone’s complex: a single-centre, 20-year experience." Cardiology in the Young 27, no. 4 (2016): 697–705. http://dx.doi.org/10.1017/s1047951116001104.

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AbstractObjectiveShone’s syndrome is a complex consisting of mitral valve stenosis in addition to left ventricle outflow obstruction. There are a few studies evaluating the long-term outcomes in this population. We sought to determine the long-term outcomes in our paediatric population with Shone’s syndrome and the factors associated with left heart growth.MethodsAll patients diagnosed with Shone’s syndrome with biventricular circulation treated between 1978 and 2010 were reviewed. Baseline echocardiograms and data from catheterisations were also reviewed. Number of interventions (surgical+tra

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20

Matwiejuk, Mateusz, Hanna Myśliwiec, Agnieszka Mikłosz, Adrian Chabowski, and Iwona Flisiak. "Is Atopic Dermatitis Associated with Systemic Metabolic Disturbances? A Systematic Review." International Journal of Molecular Sciences 26, no. 12 (2025): 5884. https://doi.org/10.3390/ijms26125884.

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Atopic dermatitis (AD) is a chronic, complex, and immunologically mediated skin disease. Its exact cause remains complex, multifaceted and yet to be discovered but is likely related to a combination of immunological, genetic and environmental factors. A medical literature search of PubMed (1992–present), Google Schoolar and Embase was performed using appropriate terms without date limitations in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Nevertheless, chronic inflammation is believed to be a major player in the development of AD

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21

Luft, Friedrich C., Okan Toka, Hakan R. Toka, Jens Jordan, and Sylvia Bähring. "Mendelian hypertension with brachydactyly as a molecular genetic lesson in regulatory physiology." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 285, no. 4 (2003): R709—R714. http://dx.doi.org/10.1152/ajpregu.00174.2003.

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Mendelian forms of hypertension have delivered a treasure trove of novel genes. To date, the molecular mechanisms of five such syndromes have been largely clarified, including glucocorticoid-remediable aldosteronism, Liddle's syndrome, apparent mineralocorticoid excess, an activating mutation of the mineralocorticoid receptor, and pseudohypoaldosteronism type 2. Each of these conditions features salt sensitivity with increased sodium and volume reabsorption by the kidney and low plasma renin activity. None of the gene loci for these syndromes has been convincingly linked to hypertension in the

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Batushkin, V. V., D. S. Podyacha, and L. O. Nesterenko. "VEGETATIVE AND CEREBRAL EFFECTS OF CARVELIS ® COMPONENTS IN PATIENTS WITH ARTERIAL HYPERTENSION." Fitoterapia 1, no. 1 (2021): 20–28. http://dx.doi.org/10.33617/2522-9680-2021-1-20.

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Key words: arterial hypertension, autonomic imbalance, dysfunction of cerebral and subcortical structures of blood pressure regulation, Carvelis treatment. In almost 36% of patients, the syndrome of arterial hypertension (AH) is determined by a combination of psychoemotional disorders with autonomic dysfunction. The aim of the study was to study the features of psychoemotional disorders and autonomic homeostasis in 78 middle-aged patients with uncomplicated hypertension and their correction using Carvelis in complex antihypertensive therapy.

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Kaw, Roop, Kara Dupuy-McCauley, and Jean Wong. "Screening and Perioperative Management of Obesity Hypoventilation Syndrome." Journal of Clinical Medicine 13, no. 17 (2024): 5000. http://dx.doi.org/10.3390/jcm13175000.

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Obesity hypoventilation syndrome (OHS) can often be underdiagnosed or misdiagnosed and has been shown to pose significant risks in perioperative situations. Patients with OHS have a higher prevalence of baseline morbid conditions like hypertension, congestive heart failure (CHF), diabetes mellitus, atrial fibrillation, and pulmonary hypertension (PH), which contribute to adverse postoperative outcomes. The potential challenges include difficult intubation and loss of airway, postoperative respiratory failure, worsening heart failure, pulmonary hypertensive crisis, and opioid-induced respirator

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Wang, Rui-feng, Chun-ze Zhou, Yu-qin Fu, and Wei-fu Lv. "Nutcracker syndrome accompanied by hypertension: a case report and literature review." Journal of International Medical Research 49, no. 1 (2021): 030006052098573. http://dx.doi.org/10.1177/0300060520985733.

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Nutcracker syndrome (NCS) refers to characteristic clinical symptoms that develop secondary to the nutcracker phenomenon (NCP), defined as compression of the left renal vein between the superior mesenteric artery and the aorta. A 22-year-old Chinese man presented with a 2-year history of hypertension and left flank pain after activity; his blood pressure fluctuated within 130–150/90–100 mmHg without treatment. He had microscopic hematuria (2+) and increased plasma renin activity. The findings of both color Doppler ultrasound and computed tomography angiography were consistent with a diagnosis

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Juan Carlos, Yugar-Toledo, Dinamarco Nelson, Rodrigues Bruno, and Moreno Heitor. "Chaos, resistant and pseudoresistant hypertension “Thousands of butterflies in the BP control system”." Journal of Cardiovascular Medicine and Cardiology 9, no. 2 (2022): 006–10. http://dx.doi.org/10.17352/2455-2976.000177.

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In Cardiology, we classify hypertensive patients as resistant to treatment, pseudo-resistant, or hyperreactivity subjects, including the WCH (white-coat or masked hypertension). Compliance is another cause of failure in antihypertensive therapy. Hypertension is a complex clinical syndrome and many variables that interfere in BP depend on “The Theory of Chaos” and are not considered. We do not know how many variations the Chaos on BP levels can be. Still, as we have around 30% of “uncontrolled” patients, the Chaos and effects on BP regulation as taking part in this high rates of “uncontrolled”

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Alkhasov, A. B., R. O. Ignatyev, A. P. Fisenko, and S. P. Yatsyk. "SURGICAL TREATMENT OF A CHILD WITH OVARICOVARICOCELE IN THE BACKGROUND OF PORTAL HYPERTENSION SYNDROME." Pediatria. Journal named after G.N. Speransky 100, no. 4 (2021): 190–93. http://dx.doi.org/10.24110/0031-403x-2021-100-4-190-193.

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A complex case report of the diagnosis and surgical correction of ovaricovaricocele (OVC) in a girl with portal hypertension syndrome is presented. The disease manifested itself with symptoms atypical for portal hypertension – dysmenorrhagia and persistent recurrent pelvic pain. The cause of OVC was thrombosis of the left renal vein after splenorenal shunt. Venous hypertension of the left kidney persisted even after creating a mesenteric-caval anastomosis and improving portal hemodynamics. Left-sided ovarian-caval shunt was made with a good clinical effect, which was confirmed by angiography.

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Chawla, Nidhi, Hinal Shah, Kathleen Huynh, Alex Braun, Hanna Wollocko, and Nilank C. Shah. "The Role of Platelet-Activating Factor and Magnesium in Obstetrics and Gynecology: Is There Crosstalk between Pre-Eclampsia, Clinical Hypertension, and HELLP Syndrome?" Biomedicines 11, no. 5 (2023): 1343. http://dx.doi.org/10.3390/biomedicines11051343.

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Clinical hypertension is a complex disease of the cardiovascular system that can affect the body’s ability to physiologically maintain homeostasis. Blood pressure is measured as systolic pressure of the heart and diastolic pressure. When the systolic pressure exceeds values of 130–139 and diastolic exceeds 80–89, the body is in stage 1 hypertension. A pregnant woman with hypertension is predisposed to developing pre-eclampsia during gestation between the 1st and 2nd trimester. If the symptoms and changes in the mother’s body are not controlled, this can progress to hemolysis, elevated liver en

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Boutgourine, Mina, Hind Nabawi, Bouchra Maatof, Mohammed El-Jamili, Saloua El-Karimi, and Mustapha El Hattaoui. "Severe Pulmonary Hypertension Secondary to Concomitant Mitral Stenosis with Veno-occlusive Disease in the Context of Systemic Sclerosis: Importance of Careful and Comprehensive Assessment." Cardiology and Angiology: An International Journal 12, no. 4 (2023): 162–70. http://dx.doi.org/10.9734/ca/2023/v12i4355.

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Pulmonary Arterial Hypertension (PAH) is a clinical syndrome consisting of physiologic/ hemodynamic criteria that are a consequence of several etiologies. Confirmation of pulmonary hypertension is based on right heart catheterization. Pulmonary hypertension is a devastating condition that can lead to considerable morbidity and premature mortality. In the last few decades, significant advancement in the pharmacotherapy of pulmonary hypertension has resulted from better understanding of the complex pathogenesis and pathophysiology of this dreaded disease. Despite these accomplishments, pha

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Krasenkov, Yu V., V. K. Tatyanchenko, Yu V. Sukhaya, and V. L. Bogdanov. "CHRONIC TISSUE HYPERTENSION IN PATIENTS SURGERED FOR INTERMUSCULAR PHLEGMONS OF THE UPPER LIMB (DIAGNOSIS, TREATMENT, PREVENTION)." Bulletin of Pirogov National Medical & Surgical Center 20, no. 2 (2025): 76–79. https://doi.org/10.25881/20728255_2025_20_2_76.

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Introduction: chronic compartment syndrome (CCS) developed after surgical treatment of intermuscular phlegmon of the upper limb is a common pathology that has a significant negative impact on the quality of life of patients in the late postoperative period. Objective: to develop an algorithm for the diagnosis and prevention of postoperative tissue hypertension (CTS) in patients with phlegmon of the upper limb. Materials and methods: results of treatment of 134 patients operated on for intermuscular phlegmon of the upper limb (IMUP) (shoulder and forearm segments). Patients were divided into 2

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McNamara, Anthony. "Metabolic syndrome." InnovAiT: Education and inspiration for general practice 12, no. 10 (2019): 582–88. http://dx.doi.org/10.1177/1755738019864615.

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Metabolic syndrome is the name given to a combination of cardiovascular risk factors. These include hyperinsulinaemia, impaired glucose tolerance, hypertension, central obesity and dyslipidaemia. People with metabolic syndrome have a high risk of developing type 2 diabetes, non-alcoholic fatty liver disease, and vascular conditions including coronary artery disease, peripheral vascular disease, and stroke. Central obesity can predispose to sleep apnoea and restrictive lung disease. For many years, it has been taught that the underlying mechanism of metabolic syndrome is insulin resistance seco

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Samiei, Niloufar, Sepehr Gohari, and Hassan Ahangar. "Delayed Diagnosis of Shone Syndrome in a Patient Planning for Pregnancy." Journal of Advances in Medical and Biomedical Research 31, no. 145 (2023): 204–6. https://doi.org/10.30699/jambs.31.145.204.

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<strong>Abstract</strong> Shone syndrome is a rare congenital cardiac abnormality; however, many of the cases remain undiagnosed until early and middle adulthood. Different imaging modalities are used to assess the related structural abnormalities. In this case study, we report a 32-year-old woman who was planning her first pregnancy. In light of her childhood heart problems, in addition to a history of extended penicillin prescriptions for several years, she was referred for complementary assessments. At the time of presentation, she was asymptomatic. Imaging results showed several structural

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Paul, Luisa, Victoria C. Ziesenitz, and Matthias Gorenflo. "Snijders Blok–Campeau Syndrome Associated with Pulmonary Arterial Hypertension: A Case Report." Reports 8, no. 2 (2025): 47. https://doi.org/10.3390/reports8020047.

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Background and Clinical Significance: We report on an infant with Snijders Blok–Campeau syndrome (psychomotor developmental delay, CNS malformations) and a complex heart defect with pulmonary arterial hypertension. Case Presentation: A DDX3X mutation encoding for RNA helicase was detected, which may suggest an association between Snijders Blok–Campeau syndrome and the development of pulmonary vasculopathy. However, further validation is required. Conclusions: We suggest an important role for DDX3X in the development of the pulmonary vasculature.

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Masriadi, Masriadi, Nur Ulmy Mahmud, Muriyati Muriyati, et al. "Determinant of metabolic syndrome." International journal of health sciences 6, no. 2 (2022): 1046–57. http://dx.doi.org/10.53730/ijhs.v6n2.10800.

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The Study aim to determinants of metabolic syndrome. Metabolic Syndrome (MetS) is a complex metabolic disorder caused by obesity, insulin resistance, diabetes mellitus, and hypertension. Aim this study is determinants of metabolic syndrome. This is a cross-sectional study, with a number of samples consisting of 192 respondents. The sample collection technique was a non-probability sampling technique with purposive sampling. The sample used in this study were outpatients at the Health Center in Ternate City, who met the following criteria: outpatients with hypertension and type 2 diabetes melli

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Gozar, Liliana, Maria Oana Săsăran, Marius Cătălin Cosma, Daniela Toma, Andreea Georgiana Nan, and Horea Gozar. "Raghib Syndrome and Pulmonary Arterial Hypertension in a Pediatric Patient: Case Report and Literature Review." Journal of Clinical Medicine 13, no. 12 (2024): 3623. http://dx.doi.org/10.3390/jcm13123623.

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Background: Raghib syndrome is a rare malformation complex consisting of the drainage of the left superior vena cava (LSVC) into the left atrium, ostial atresia of the coronary sinus and an atrial septal defect (ASD). Case Report: This report aims to present the case of a child newly diagnosed with Raghib syndrome, complicated by pulmonary arterial hypertension, and to review previously published cases with the same diagnosis. A six-year-old female patient presented with signs and symptoms of heart failure (Ross III), reduced exercise tolerance and severe delay in stature and ponderal developm

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Reel, Smarti, Parminder S. Reel, Zoran Erlic, et al. "Predicting Hypertension Subtypes with Machine Learning Using Targeted Metabolites and Their Ratios." Metabolites 12, no. 8 (2022): 755. http://dx.doi.org/10.3390/metabo12080755.

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Hypertension is a major global health problem with high prevalence and complex associated health risks. Primary hypertension (PHT) is most common and the reasons behind primary hypertension are largely unknown. Endocrine hypertension (EHT) is another complex form of hypertension with an estimated prevalence varying from 3 to 20% depending on the population studied. It occurs due to underlying conditions associated with hormonal excess mainly related to adrenal tumours and sub-categorised: primary aldosteronism (PA), Cushing’s syndrome (CS), pheochromocytoma or functional paraganglioma (PPGL).

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Battisha, Ayman, Amrit Kahlon, and Dinesh K. Kalra. "Sleep-Disordered Breathing and Hypertension—A Systematic Review." Journal of Clinical Medicine 14, no. 9 (2025): 3115. https://doi.org/10.3390/jcm14093115.

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Background/Objectives: Sleep-disordered breathing (SDB), historically referred to as “sleep apnea syndrome”, particularly obstructive sleep apnea (OSA), is an independent risk factor for hypertension (HTN), stroke, heart failure, arrhythmias, and other cardiovascular disorders. Despite the well-established link between OSA and HTN and its high occurrence in cardiovascular disorders, the focus on the complex OSA–HTN axis is often overlooked or inadequately managed, which might explain the lack of notable improvements in cardiovascular outcomes for this patient population. Understanding the comp

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Eddakhche MD, Hicham, Wassim Beladel MD, and Mohamed El Minaoui MD. "ACUTE RESPIRATORY DISTRESS REVEALING A COMPLETE ATRIOVENTRICULAR CANAL IN A 22-MONTH INFANT." International Journal of Advanced Research 12, no. 10 (2024): 720–23. http://dx.doi.org/10.21474/ijar01/19690.

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The atrioventricular canal (AVC) is a complex and rare congenital cardiac anomaly. It is potentially severe due to the complexity of its lesions and associated fixed pulmonary arterial hypertension. We report the case of a 22-month-old infant girl with Trisomy 21 syndrome, admitted for acute respiratory distress. TTE showed a complete AVC with pulmonary arterial hypertension. Prognosis depends on the promptness of diagnosis and therapeutic management.

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Achim, Camelia-Adriana, Cătălina Voicu-Titere, Georgiana Aurelia Nae, Daniela-Gabriela Florescu, Rareș-Vasilică Moisa, and Gener Ismail. "Complement Blockade, a New Therapeutic Approach in Malignant Hypertension." Internal Medicine 21, no. 1 (2024): 105–15. http://dx.doi.org/10.2478/inmed-2024-0283.

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Abstract Atypical hemolytic uremic syndrome (aHUS) represents a major challenge due to its rare nature and severe impact on patients, characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. This paper describes the case of a 41-year-old patient diagnosed with aHUS in the context of malignant arterial hypertension and severe renal impairment, manifested by anuria and significant azotemic retention syndrome. The complex management of the case, including the use of Eculizumab, a complement inhibitor, highlighted significant therapeutic benefits, especially i

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Achim, Camelia-Adriana, Cătălina Voicu-Titere, Georgiana Aurelia Nae, Daniela-Gabriela Florescu, Rareș-Vasilica Moisa, and Gener Ismail. "Complement Blockade, a New Therapeutic Approach in Malignant Hypertension." Internal Medicine 20, no. 4 (2023): 97–107. http://dx.doi.org/10.2478/inmed-2023-0272.

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Abstract Atypical hemolytic uremic syndrome (aHUS) represents a major challenge due to its rare nature and severe impact on patients, characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. This paper describes the case of a 41-year-old patient diagnosed with aHUS in the context of malignant arterial hypertension and severe renal impairment, manifested by anuria and significant azotemic retention syndrome. The complex management of the case, including the use of Eculizumab, a complement inhibitor, highlighted significant therapeutic benefits, especially i

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Fountain, John H., Tyler J. Peck, and David Furfaro. "Sequelae of Acute Pulmonary Embolism: From Post-Pulmonary Embolism Functional Impairment to Chronic Thromboembolic Disease." Journal of Clinical Medicine 13, no. 21 (2024): 6510. http://dx.doi.org/10.3390/jcm13216510.

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Among survivors of acute pulmonary embolism (PE), roughly half report persistent dyspnea, impaired functional status, and decreased quality of life. Post-pulmonary embolism syndrome (PPES) is a broad condition which has been increasingly recognized in recent years and may be due to post-pulmonary embolism functional impairment, chronic thromboembolic disease, or the most severe long-term complication of PE, chronic thromboembolic pulmonary hypertension. Despite guideline recommendations for appropriate follow-up for post-pulmonary embolism patients, PPES remains underrecognized and diagnostic

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Donova, L. V., M. S. Novruzbekov, and V. E. Syutkin. "Complex ultrasonography in the assessment of intrarenal hemodynamic impairments in patients with portal hypertension." Transplantologiya. The Russian Journal of Transplantation 13, no. 1 (2021): 25–32. http://dx.doi.org/10.23873/2074-0506-2021-13-1-25-32.

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Rationale. Hepatorenal syndrome is a threatening complication in patients with liver cirrhosis and portal hypertension. The occurrence of renal dysfunction associated with hepatorenal syndrome manifestations significantly affects the condition severity, the disease duration, and the survival time during the waiting period for liver transplantation.The study purpose was to investigate the potential of a complex ultrasonography examination in the assessment of intrarenal hemodynamic impairments in patients with various diffuse liver diseases.Material and methods. The ultrasound examination resul

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Mabillard, Holly, and John A. Sayer. "The Molecular Genetics of Gordon Syndrome." Genes 10, no. 12 (2019): 986. http://dx.doi.org/10.3390/genes10120986.

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Gordon syndrome is a rare inherited monogenic form of hypertension, which is associated with hyperkalaemia and metabolic acidosis. Since the recognition of this predominantly autosomal dominant condition in the 1960s, the study of families with Gordon syndrome has revealed four genes WNK1, WNK4, KLHL3, and CUL3 to be implicated in its pathogenesis after a phenotype–genotype correlation was realised. The encoded proteins Kelch-like 3 and Cullin 3 interact to form a ring-like complex to ubiquitinate WNK-kinase 4, which, in normal circumstances, interacts with the sodium chloride co-symporter (NC

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Beres, Shannon J. "Update in Pediatric Pseudotumor Cerebri Syndrome." Seminars in Neurology 40, no. 03 (2020): 286–93. http://dx.doi.org/10.1055/s-0040-1708847.

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AbstractPseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idiopathic, also known as idiopathic intracranial hypertension or primary intracranial hypertension, or can be secondary to medications and associated medical conditions. Given the threat to vision, early detection and treatment is needed in all age groups. However, identifying papilledema or pseudopapilledema in children presents unique challenges sometimes as a result of differences between

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Reddy Gangireddy, Venkata, Bandi Venkata Varshitha, Srinivasa Reddy Annapureddy, Bhargavi Chadarajupalli, and Ravikanth Reddy Yalamuri. "Complex presentation of atypical hemolytic uremic syndrome: A case study." Indian Journal of Case Reports 10, no. 9 (2024): 289–92. http://dx.doi.org/10.32677/ijcr.v10i9.4690.

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This case study discusses atypical hemolytic uremic syndrome (aHUS) in a 67-year-old female who presented with hypertension and hyperlipidemia 8 days after a suspected foodborne illness. Her initial presentation included acute respiratory and renal failure in which her condition required extensive re-warming, intubation, pressor or vasopressor therapy, continuous renal replacement therapy or hemodialysis, broad-spectrum antibiotic therapy, and blood and culture workups. Kidney function also showed signs of renal failure, metabolic acidosis, thrombocytopenia, and an elevated level of lactate de

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Matyunova, A. E., S. A. Sakhovsky, L. V. Bregel, et al. "TREATMENT TACTICS FOR SEVERE REFRACTORY ARTERIAL HYPERTENSION IN AN ADOLESCENT WITH ABDOMINAL AORTIC HYPOPLASIA AND RENAL ARTERY STENOSIS. A CLINICAL CASE." Pediatria. Journal named after G.N. Speransky 102, no. 5 (2023): 237–45. http://dx.doi.org/10.24110/0031-403x-2023-102-5-237-245.

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Renovascular arterial hypertension (AH) is one of the most common and prognostically most serious secondary hypertensions in children, however, descriptions of renal artery stenosis as part of middle aortic syndrome are quite rarely described Worldwide, and the etiology of this syndrome remains unclear in more than half of all the cases. Treatment approaches include a combination of complex conservative and surgical endovascular techniques that require constant monitoring of effectiveness. A clinical case observation and treatment tactics for refractory hypertension in an adolescent patient wi

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Wang, Song, Mei Xiao, Liqun Hua, Yong Jia, Si Chen, and Kaiguang Zhang. "Endoscopic therapy for gastro-oesophageal varices of Caroli’s syndrome: a case report." Journal of International Medical Research 48, no. 2 (2019): 030006051987799. http://dx.doi.org/10.1177/0300060519877993.

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Caroli’s disease (CD) is a very rare congenital disorder that is characterized by non-obstructive, segmental and cystic dilatation of intrahepatic ducts. Most patients with CD are asymptomatic, but some patients may suffer from hepatic fibrosis, liver cirrhosis or/and portal hypertension. In complex CD, cystic dilatations of the intrahepatic bile ducts can be present with congenital hepatic fibrosis, liver cirrhosis, portal hypertension, oesophageal varices and autosomal recessive polycystic kidney disease; a condition known as Caroli’s syndrome. This report describes the case of a 28-year-old

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Cuda, Cristina. "The role of inflammation in metabolic syndrome." SURG Journal 1, no. 2 (2008): 82–90. http://dx.doi.org/10.21083/surg.v1i2.406.

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The metabolic consequences of obesity have made this highly prevalent condition one of the most common risk factors for type 2 diabetes, hypertension and atherosclerosis. Simultaneous occurrence of these conditions can be explained through the manifestations of metabolic syndrome [MetS]. Clinical indication of MetS is characterized by a clustering of risk factors for complex chronic diseases which all feature metabolic deterioration as a common component. Diagnosis of MetS can be made if a patient exhibits three of the identified risk factors, some of which include: elevated waist circumferenc

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Karimdzhanov, I. A., G. Kh Iskanova, and N. A. Israilova. "Arterial hypertension in children with nephrotic syndrome." Nephrology (Saint-Petersburg) 25, no. 3 (2021): 20–27. http://dx.doi.org/10.36485/1561-6274-2021-25-3-20-27.

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The review presents materials on the prevalence of NS in children, variants of its course: steroid-sensitive (SSNS) and steroidresistant (SRNS) steroid-dependent (SSNS). Minimal change nephrotic syndrome minimal changes (NSMC) is the most common glomerular disorder. Although NSMC has an excellent prognosis with a low risk of progression to t-CRF, its recurrent nature requires children to receive frequent courses of steroid therapy and other medications, many of which are known to affect blood pressure (BP). The interrelation of NS in children with arterial hypertension (AH) is shown. Prevalenc

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Ong, Jay Mark Zapanta, and Ryan Martin V. Obnamia. "The Anesthetic Management of Shone’s Complex." Philippine Journal of Anesthesiology 30, no. 1 (2025): 45–50. https://doi.org/10.4103/pja.pja_8_25.

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Shone’s complex is a rare congenital cardiac malformation characterized by four obstructive lesions affecting the left heart and aortic arch: supramitral membrane, parachute mitral valve, subaortic stenosis, and aortic coarctation, typically presenting in an incomplete form. We report the case of a 6-year-old female with a variant of Shone’s complex, which included subvalvular aortic stenosis, mitral valve stenosis, hypoplastic aortic arch, coarctation of the aorta, and patent ductus arteriosus. Surgical intervention is required in approximately 40% of cases, particularly when accompanied by e

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Ali Y. "Lutembacher Syndrome." Journal of Diabetic Association Medical College, Faridpur 1, Number 1 (2017): 37–39. http://dx.doi.org/10.70357/jdamc.2017.v0101.09.

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Lutembacher syndrome a rare complex heart disease comprises ASD (secundum) with mitral stenosis. ASD (Secundum)usually congenital but may be iatrogenic during IAS puncture during PTMC procedure. MS usually rheumatic origin. OurPatient Mrs. Fulmala, 60 yrs. old, housewife, non hypertensive, non diabetic admitted in DAMCH cardiac unit on 10.11.12with the complaints of progressive respiratory distress for ten years, cough for 5 yrs, chest pain for 2 yrs. Initially shortness ofbreath was in NYHA class II & at present it in NYHA class-III. She had a previous history of rheumatic fever in earlyc

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