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1

Rahman, Rahnuma, and Supriyo Bandyopadhyay. "The Cost of Energy-Efficiency in Digital Hardware: The Trade-Off between Energy Dissipation, Energy–Delay Product and Reliability in Electronic, Magnetic and Optical Binary Switches." Applied Sciences 11, no. 12 (2021): 5590. http://dx.doi.org/10.3390/app11125590.

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Binary switches, which are the primitive units of all digital computing and information processing hardware, are usually benchmarked on the basis of their ‘energy–delay product’, which is the product of the energy dissipated in completing the switching action and the time it takes to complete that action. The lower the energy–delay product, the better the switch (supposedly). This approach ignores the fact that lower energy dissipation and faster switching usually come at the cost of poorer reliability (i.e., a higher switching error rate) and hence the energy–delay product alone cannot be a g
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Gohil, S. "POS0626 MONEY MATTERS: ASSESSING THE VALUE OF THE ADALIMUMAB BIOSIMILAR SWITCH FOR RHEUMATOLOGY PATIENTS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 551.2–551. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2566.

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Background:The adalimumab biosimilar switch plan, actioned 2018-19 was one of the most complex of all biologic switches across several specialties. Non-medical switches are considered to ensure the best value medicines are prescribed for patients in line with NICE Technology Appraisals.Objectives:This 2 year follow up review explores the value of the switch for Rheumatology (R) patients in comparison to two other major specialisms; Dermatology (R) and Gastroenterology (G).Methods:403 homecare (HC) patients had been identified as eligible for switch to a citrate containing biosimilar (R;189, G;
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Gadzhanova, Svetla, Elizabeth E. Roughead, and Lisa G. Pont. "Antidepressant switching patterns in the elderly." International Psychogeriatrics 30, no. 9 (2018): 1365–74. http://dx.doi.org/10.1017/s1041610217002964.

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ABSTRACTBackground:Switching between antidepressants is complex due to potential adverse outcomes such as serotonin syndrome and antidepressant discontinuation syndrome, yet switching is often required due to non-response to initial treatment. This study aimed to examine the patterns and extent of antidepressant switching in a cohort of older adults in long-term residential care.Methods:A cohort study of medication supply data from 6011 aged care residents in 60 long-term care facilities was conducted. Incident antidepressant users were followed for 12 months and their patterns of antidepressa
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Barabanova, E. A., K. A. Vytovtov, V. M. Vishnevsky, and V. S. Podlazov. "The method for constructing fault-tolerant photonic switches for high-performance computing systems." Journal of Physics: Conference Series 2091, no. 1 (2021): 012032. http://dx.doi.org/10.1088/1742-6596/2091/1/012032.

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Abstract In this paper the new type of fault-tolerant non-blocking photonic switch is presented for the first time. The proposed switch architecture is based on quasi-complete graph topology which use provides non-blocking and fault-tolerant switching process. The new two-stage switch architecture uses the stage of dual photonic switches and pairs of photonic demultiplexers and multiplexers which have been described in detail by authors in their previous works. Depending on the number of different backup connections, the two types of fault-tolerant pho-tonic switches are considered in this pap
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Zhen, Qihui, and Qingyun Di. "Soft-Switching Technology of Three-Phase Six-Switch PFC Rectifier." Energies 13, no. 19 (2020): 5130. http://dx.doi.org/10.3390/en13195130.

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An active clamp, three-phase, six-switch power factor correction rectifier with a one-cycle controller is proposed, which can effectively suppress the reverse recovery of the reverse parallel diode of the bridge arm switch and reduce the reverse recovery loss. The main switches and auxiliary switch are both zero-voltage switches. It works in a fixed switching frequency and low power stress during the switching period. The specific working process and control circuit are analyzed in detail, and the model simulation is carried out. The experimental platform of a 2.5 KW prototype, with a complete
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Harrell, Morgan, Daniel Fabbri, and Mia Levy. "Analysis of Adjuvant Endocrine Therapy in Practice From Electronic Health Record Data of Patients With Breast Cancer." JCO Clinical Cancer Informatics, no. 1 (November 2017): 1–8. http://dx.doi.org/10.1200/cci.16.00044.

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Purpose Adjuvant endocrine therapy is a long-term drug therapy prescribed to prevent recurrence of hormone receptor–positive breast cancer. Data on adjuvant endocrine therapy are reported though clinical trials, which may differ from treatment practice and outcomes in the general population of patients with breast cancer. With secondary use of electronic health record (EHR) data, we summarize adjuvant endocrine treatment practice and outcomes in real-world settings. Methods We analyzed treatment data derived from EHR data on 1,587 patients with stage I to III breast cancer at a National Cancer
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Painchaud, M., S. Singh, and R. M. Penner. "A147 SIMILAR OUTCOMES IN PATIENTS SWITCHED TO INFLIXIMAB BIOSIMILARS COMPARED TO THOSE REMAINING ON REMICADE IN A BRITISH COLUMBIA INFLAMMATORY BOWEL DISEASE PRACTICE." Journal of the Canadian Association of Gastroenterology 5, Supplement_1 (2022): 20–21. http://dx.doi.org/10.1093/jcag/gwab049.146.

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Abstract Background In 2019 the Canadian province of British Columbia (BC) launched an initiative to switch inflammatory bowel disease (IBD) patients on the infliximab originator, Remicade, to biosimilars Inflectra or Renflexis. Evidence shows that such switches can be made without compromising efficacy or safety of treatment. Aims We examined results in a large IBD practice, with the hypothesis that patients required to switch to a biosimilar would have similar remission rates to those who remained on Remicade. Methods A total of 113 patients were included in this retrospective chart study. 8
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Szurek, P., J. Petrini, and W. Dunnick. "Complete nucleotide sequence of the murine gamma 3 switch region and analysis of switch recombination sites in two gamma 3-expressing hybridomas." Journal of Immunology 135, no. 1 (1985): 620–26. http://dx.doi.org/10.4049/jimmunol.135.1.620.

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Abstract The heavy chain isotype switch is mediated by a DNA rearrangement between a donor switch region (usually mu) and a recipient switch region (gamma, epsilon, or alpha). Switch regions lie upstream of the appropriate heavy chain constant region gene and are composed of simple sequences repeated in tandem. It is not known to what extent the tandemly repeated sequences are important to the heavy chain switch recombination, and to what extent other features of switch region sequences might contribute to the switch process. We studied switches to the gamma 3 isotype by sequencing the entire
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Benavides-Córdoba, Santiago, Anamaría Romero-Carvajal, Nicolas Muñoz-Galeano, Juan Bernardo Cano-Quintero, and Jesús María López-Lezama. "Deduction and Application of the Average Switch Model in Power Electronic Devices for Simulation Time Reduction." Ingeniería 29, no. 1 (2024): e21303. http://dx.doi.org/10.14483/23448393.21303.

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Context: Time is a crucial issue in the simulation of power electronics (PE) devices, even more when these elements are integrated into microgrids.Method: This paper deals with the deduction of the average switch model for PE devices with the purpose of reducing simulation times. For doing this, the average model is only applied over the power switches of PE devices, not being applied over the complete topology as traditionally done. The proposed average model switch permits eliminating the ripple of voltage and currents but keeping the transient of the signals. The average model switch is der
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Su, Yinsheng, Qian Ma, Haicheng Yao, Lei Shao, and Shujun Yao. "Research on simultaneous switch and multiple switch processing methods." Journal of Physics: Conference Series 2728, no. 1 (2024): 012055. http://dx.doi.org/10.1088/1742-6596/2728/1/012055.

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Abstract In the simulation of complex power electronic equipment containing multiple power electronic switches, it is often encountered that the same switch occurs several times in one step, or there are multiple switch actions in one step, that is, multiple switches. When the switching event occurs between two moments, because the voltage value can only be updated at the end of the simulation step, there is a cumulative error in the current obtained by the integration. In traditional electromagnetic transient simulation, the interpolation algorithm and its deformation are commonly used to sol
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11

Gillies, C. B., J. Kuspira, and R. N. Bhambhani. "Genetic and cytogenetic analyses of the A genome of Triticum monococcum. IV. Synaptonemal complex formation in autotetraploids." Genome 29, no. 2 (1987): 309–18. http://dx.doi.org/10.1139/g87-051.

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Electron microscopy of synaptonemal complex spreads from autotetraploid Triticum monococcum (2n = 4x = 28) revealed a minimum mean of 3.59 multivalents per zygotene–pachytene nucleus. The range of values was from 1 to 6 multivalents per nucleus. Most of the multivalents were quadrivalents with single, medially located pairing partner switch points. Lateral element pairing switches, particularly the few multiple switches, were often accompanied by extensive asynapsis around the switch point. The synaptonemal complex multivalent frequency is considerably higher than the metaphase I quadrivalent
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Agarwal, Rupali, Neelam Srivastava та Himanshu Katiyar. "Theoretical Investigation of Different Diversity Combining Techniques in Cognitive Radio". Journal of Telecommunications and Information Technology 3 (28 вересня 2018): 64–69. http://dx.doi.org/10.26636/jtit.2018.124618.

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In this paper, the performance of an energy detector in cognitive radio, using different diversity combining techniques, is evaluated. Among many diversity combining techniques, maximal ratio combining (MRC) gives the best results but at the cost of the highest complexity. To design a simpler receiver, it is suggested to use less complex combining techniques, i.e. switched diversity, which provides one of the least complex solutions to combat fading. The paper analyzes two switched diversity schemes, switch examine combining (SEC), and switch examine combining with post examining selection (SEC
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13

Ritter, T. E., S. A. Mehta, and L. J. Van Anglen. "P483 Patient-reported quality of life, anxiety, and depression associated with switching originator infliximab to biosimilar." Journal of Crohn's and Colitis 16, Supplement_1 (2022): i450—i451. http://dx.doi.org/10.1093/ecco-jcc/jjab232.610.

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Abstract Background Non-medical switching from biologics to biosimilars is becoming increasingly common. Previous studies have demonstrated efficacy and safety of switching originator to biosimilar infliximab in inflammatory bowel disease (IBD) patients. Limited data exist on patient-reported quality of life (QOL) and possible emotional duress associated with these switches. The purpose of this study was to describe the impact of non-medical switches to infliximab biosimilars on QOL, anxiety, and depression. Methods This was a retrospective review of all IBD patients switched from originator t
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14

Barabanova, E. A., K. A. Vytovtov, V. M. Vishnevsky, and V. S. Podlazov. "High-capacity strictly non-blocking optical switches based on new dual principle." Journal of Physics: Conference Series 2091, no. 1 (2021): 012040. http://dx.doi.org/10.1088/1742-6596/2091/1/012040.

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Abstract In this paper the new dual principle of designing high-capacity strictly non-blocking optical switches is presented for the first time. The new type of switches with decentralized control based on the dual principle has been developed for the first time too. In accordance with the scheme topology this type of switching system was called as the quasi-complete dual switch. It also is analysed the optical signals minimal transmission time that provide the non-blocking property of the new schemes. For the circuit and link complexity calculations the accurate analytical expressions are obt
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Mao, Jianbin, Micheal Johnson, Jeffrey Mcpheeters, Girish Prajapati, and Andrew Beyer. "Healthcare Resource Utilization and Costs Associated with Switching First-line Antiretroviral Therapy among HIV-infected Patients in the United States." Open Forum Infectious Diseases 4, suppl_1 (2017): S435—S436. http://dx.doi.org/10.1093/ofid/ofx163.1101.

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Abstract Background Initial antiretroviral therapy (ART) is modified for non-virologic failure reasons in many patients, and the healthcare resource utilization (HRU) and costs associated with these switches in the real world is not well understood. Methods Administrative claims data from the Optum Research and Impact National Benchmark Databases were utilized. Adult patients (≥18 years) with HIV-1 diagnosis code, and claim for an anchor agent of the protease inhibitor (PI) or non-nucleoside reverse transcriptase inhibitor (NNRTI) class in first-line ART between July 1, 2006 and December 31, 2
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16

Fu, Wenwen, Tao Li, and Zhigang Sun. "FAS: Using FPGA to Accelerate and Secure SDN Software Switches." Security and Communication Networks 2018 (2018): 1–13. http://dx.doi.org/10.1155/2018/5650205.

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Software-Defined Networking (SDN) promises the vision of more flexible and manageable networks but requires certain level of programmability in the data plane to accommodate different forwarding abstractions. SDN software switches running on commodity multicore platforms are programmable and are with low deployment cost. However, the performance of SDN software switches is not satisfactory due to the complex forwarding operations on packets. Moreover, this may hinder the performance of real-time security on software switch. In this paper, we analyze the forwarding procedure and identify the pe
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Bezrodna, T. V., A. М. Negriyko, V. I. Bezrodnyi, I. V. Matsnev, L. F. Kosyanchuk, and O. I. Antonenko. "Efficient passive laser Q-switches based on dye-doped polyurethane for high-energy neodymium lasers." Semiconductor Physics, Quantum Electronics and Optoelectronics 28, no. 01 (2025): 083–92. https://doi.org/10.15407/spqeo28.01.083.

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This paper studies energy and time operation characteristics of a laser on a Nd3+:YAG crystal with passive Q-switches based on a dye-activated aliphatic polyurethane matrix with high radiation strength. A high efficiency of laser generation both in a free mode and at single pulse generation in the Q-switched regime is obtained using a samarium diffuse reflector with a BaSO4 filler. A single pulse energy and duration for the lasers with passive Q-switches based on organo-nickel complex BDN and polymethine dye IR-1061 in an aliphatic polyurethane matrix polymerized by the polycondensation method
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18

Zhan, Zhuozhao, Geertruida H. de Bock, and Edwin R. van den Heuvel. "Statistical methods for unidirectional switch designs: Past, present, and future." Statistical Methods in Medical Research 27, no. 9 (2017): 2872–82. http://dx.doi.org/10.1177/0962280216689280.

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Clinical trials may apply or use a sequential introduction of a new treatment to determine its efficacy or effectiveness with respect to a control treatment. The reasons for choosing a particular switch design have different origins. For instance, they may be implemented for ethical or logistic reasons or for studying disease-modifying effects. Large-scale pragmatic trials with complex interventions often use stepped wedge designs (SWDs), where all participants start at the control group, and during the trial, the control treatment is switched to the new intervention at different moments. They
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Reising, John M., and David C. Hartsock. "Advanced Warning/Caution/Advisory Displays for Fighter Aircraft." Proceedings of the Human Factors Society Annual Meeting 33, no. 2 (1989): 66–70. http://dx.doi.org/10.1177/154193128903300214.

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The primary purpose of this study was to determine the effectiveness of using color cathode ray tube (CRT) checklists and programmable multifunction switches to display warning/caution/advisory (W/C/A) information. This study compared three different display formats on speed and accuracy of recognition and execution of emergency procedures. The following three different W/C/A formats were tested: 1) Abbreviated title of the emergency written on a CRT [e.g., ELEC SYS/MAIN GEN], with the pilot using his knee pad checklist to complete the required steps, 2) Complete title with the checklist shown
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Li, Wenjie, Yiping Gong, and Bin Liu. "Performance Evaluation of Crossbar Switch Fabrics in Core Routers." Journal of Interconnection Networks 04, no. 02 (2003): 163–77. http://dx.doi.org/10.1142/s0219265903000805.

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Many researchers have pointed out that using complex scheduling algorithms in input queuing switches with virtual output queuing (VOQ) scheme can achieve 100% throughput. But these algorithms are too complex to be implemented in hardware. In this paper, based on combined input/output queuing (CIOQ) switch fabrics, we propose a simple scheduling algorithm named outlet priority round robin (OPRR). For synthetic workloads we consider, including uniform and bursty traffic models, the performance of OPRR in VOQ mode and single queue mode is evaluated respectively. Through the simulation results we
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Promponas, Panagiotis, V´ctor Valls, and Leandros Tassiulas. "Quantum Switch Scheduling for Information Qubits." ACM SIGMETRICS Performance Evaluation Review 51, no. 2 (2023): 78–80. http://dx.doi.org/10.1145/3626570.3626598.

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This paper studies the problem of designing a scheduling policy for a quantum switch that teleports information qubits. The problem is analogous to scheduling photons in highspeed optical switches, with the difference that an optical switch is modeled as a bipartite graph instead of a complete graph. The paper's contributions are to model the problem of designing a scheduling policy as decomposing a symmetric doubly stochastic matrix, and to show that we can use Birkhoff's algorithm to obtain such a decomposition.
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Hagan, Iain M., and Agnes Grallert. "Spatial control of mitotic commitment in fission yeast." Biochemical Society Transactions 41, no. 6 (2013): 1766–71. http://dx.doi.org/10.1042/bst20130190.

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The activation of the Cdk1 (cyclin-dependent kinase 1)–cyclin B complex to promote commitment to mitosis is controlled by the phosphorylation status of the Cdk1 catalytic subunit. Cdk1 phosphorylation by Wee1 kinases blocks activation until Cdc25 (cell division cycle 25) phosphatases remove this phosphate to drive division. Feedback inhibition of Wee1 and promotion of Cdc25 activities by the newly activated Cdk1–cyclin B complexes ensure that the transition from interphase to mitosis is a rapid and complete bi-stable switch. Although this level of molecular understanding of the mitotic commitm
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Amelin, Sergey, Marina Arkad'evna Amelina, Sergey Vladimirovich Drozdetsky, and Igor Vladimirovich Yakimenko. "MODEL OF SWITCH-CONTROLLED PWM STRUCTURE FOR ANALYSIS OF PULSE VOLTAGE CONVERTERS WITH ARBITRARY TOPOLOGY." Vestnik of Astrakhan State Technical University. Series: Management, computer science and informatics 2021, no. 4 (2021): 45–57. http://dx.doi.org/10.24143/2072-9502-2021-4-45-57.

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The article considers the problems of analyzing DC-DC voltage converters and analyzes the advantages, disadvantages, as well as the scope of full switched and averaged continuous models of the converters. The feasibility of using the complex of two models (full switch model and averaged continuous model) for analyzing their operation is proved. The general approach to the construction of continuous models of DC-DC voltage converters based on state-space averaging method is considered. Disadvantages of the averaged models using a classic approach are shown. The relevance of the development of u
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Hashemi, Babak, Teresa Crisci, Mohamed Mameri, et al. "Design and Simulation of a silicon electro-optic microring switch with a graphene modulating layer." EPJ Web of Conferences 309 (2024): 01005. http://dx.doi.org/10.1051/epjconf/202430901005.

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This paper presents a comprehensive simulation study on the design and simulation of an electro-optic ring switch utilizing graphene material. The switch employs the electrically Tunable Refractive Index by graphene to modulate the transmission characteristics within a ring resonator structure. By applying an electrical voltage ranging from -6 to -10V, significant changes are noticed in the output ports' transmission characteristics. In particular, the transmission through the output ports varies between 81% to 18% for output port n.1 and 21% to 83%for output port no.2, proving that signal pro
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Zhang, Hanting. "CAD-Assisted 3D Assembly of Automobile Electrical Switch considering PSO-BP Neural Network Algorithm." Journal of Electrical and Computer Engineering 2022 (May 5, 2022): 1–11. http://dx.doi.org/10.1155/2022/6454942.

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The installation of automotive electrical switches is a complex three-dimensional space assembly project which has high requirements for installation accuracy. In order to improve the installation effect of automotive electrical switches, this paper applies the PSO-BP neural network algorithm to automotive electrical switches and integrates PSO and ELM algorithms. The training speed of the ELM model is fast, the model generalizes the data well, and the noise data have little effect on the model. Moreover, this article combines simulation research to evaluate the effect of this algorithm. After
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Feng, Jiacheng, Jun Ma, ZaiYan Gong, Di Kang, and Chao Wang. "Design of Multi-threshold Acceleration Switch Based on Matlab." MATEC Web of Conferences 232 (2018): 04026. http://dx.doi.org/10.1051/matecconf/201823204026.

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Acceleration switch can trigger switches according to the variation of external acceleration without complex control system and circuit. With the excellent characteristics of integration of sensor and actuator, zero power consumption and high reliability, multi-threshold acceleration switch has great application value in the fields of vehicle safety, aerospace and industrial equipment. In order to reduce the complexity of the measurement system and improve the reliability, we realized the design of a multi-threshold and anti-overloading acceleration switch which can distinguish specific pulse
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He, Bo, Yong Yuan, Jie Ren, et al. "A High-Functional-Density Integrated Inertial Switch for Super-Quick Initiation and Reliable Self-Destruction of a Small-Caliber Projectile Fuze." Micromachines 14, no. 7 (2023): 1377. http://dx.doi.org/10.3390/mi14071377.

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With the aim of achieving the combat technical requirements of super-quick (SQ) initiation and reliable self-destruction (SD) of a small-caliber projectile fuze, this paper describes a high-functional-density integrated (HFDI) inertial switch based on the “ON-OFF” state transition (i.e., almost no terminal ballistic motion). The reliable state switching of the HFDI inertial switch is studied via elastic–plastic mechanics and verified via both simulations and experiments. The theoretical and simulation results indicate that the designed switch can achieve the “OFF-ON” state transition in the in
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Santos, Raqueline A. M. "Quantum state transfer on the complete bipartite graph." Journal of Physics A: Mathematical and Theoretical 55, no. 12 (2022): 125301. http://dx.doi.org/10.1088/1751-8121/ac5217.

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Abstract Previously it was shown that (almost) perfect state transfer can be achieved on the complete bipartite graph by a discrete-time coined quantum walk based algorithm when both the sender and receiver vertices are in the same partition of the graph and when the sender and receiver are in opposite partitions of the same size. By changing the coin operator, we analyze the state transfer problem and we show that it is still possible to achieve state transfer with high fidelity even when the sender and receiver are in different partitions with different sizes. Moreover, it is also possible t
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Suppadungsuk, Supawadee, Purim Janepiriyaprayoon, and Somnuek Sungkanuparph. "Recovery of renal function after early versus late switching of tenofovir disoproxil fumarate in people living with HIV with renal insufficiency." International Journal of STD & AIDS 33, no. 4 (2022): 391–96. http://dx.doi.org/10.1177/09564624221076632.

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Background Although many guidelines recommend switching tenofovir disoproxil fumarate (TDF) to other antiretroviral agents if there is a progressive decline in the estimated glomerular filtration rate (eGFR) not explained by other causes, a definite cut-point of the eGFR for TDF switching is not known. Methods A cohort study was conducted among people living with HIV (PLHIV) who switched from TDF to other agents due to declined eGFR. Participants were categorized according to the eGFR at TDF switching: early-switch (eGFR ≥ 60 mL/min/1.73 m2) and late-switch (eGFR < 60 mL/min/1.73 m2) groups
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Hu, M. H., Y. L. Lv, and Na Wang. "The Analysis of an Accident in Coal Mine which Caused by Short-Circuit of 6kv High-Pressure Explosion-Proof Switch." Applied Mechanics and Materials 143-144 (December 2011): 27–31. http://dx.doi.org/10.4028/www.scientific.net/amm.143-144.27.

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To describe 6kv high-pressure explosion-proof switches, the main device of ensuring the safe operation of in coal mine power supply system, are widely used in coal mine, which can complete the mission of underground high-voltage power supply and distribution and the controlling of high-pressure water pump motor. The short-circuit of high-pressure explosion-proof switch is not a common fault, but the event usually cause a large area power outage, especially at high gas underground mine, which is a serious threat to production safety. In this paper, the analysis of switch short-circuit accident
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Xie, Si Zhe, Jin Sha Yuan, and Zhi Yuan Xie. "Design of Power Supply System for 10kV Smart Switch Based on PV Technologies." Advanced Materials Research 744 (August 2013): 547–51. http://dx.doi.org/10.4028/www.scientific.net/amr.744.547.

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With the rapid development of the smart grid in our country, we need many 10kV smart switches which can protect the safety of the line and complete the reasonable scheduling of the electricity load. In order to realize the reliable power supply for 10kV smart switch, power supply system based on photovoltaic cell technology is designed. In this paper, firstly, we have a brief introduction about the 10kV smart switch. Secondly, composing and principle of the power supply system is introduced. And then, principle of the energy harvesting converter main circuit is analyzed in detail. Then, the MP
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Grass, Jeffrey A., Huie Jing, Shin-Il Kim, et al. "Distinct Functions of Dispersed GATA Factor Complexes at an Endogenous Gene Locus." Molecular and Cellular Biology 26, no. 19 (2006): 7056–67. http://dx.doi.org/10.1128/mcb.01033-06.

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ABSTRACT The reciprocal expression of GATA-1 and GATA-2 during hematopoiesis is an important determinant of red blood cell development. Whereas Gata2 is preferentially transcribed early in hematopoiesis, elevated GATA-1 levels result in GATA-1 occupancy at sites upstream of the Gata2 locus and transcriptional repression. GATA-2 occupies these sites in the transcriptionally active locus, suggesting that a “GATA switch” abrogates GATA-2-mediated positive autoregulation. Chromatin immunoprecipitation (ChIP) coupled with genomic microarray analysis and quantitative ChIP analysis with GATA-1-null c
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Singh, Rajendra, Anjana Singh, and Sharmila Pandey. "Ability of the Aphid Parasitoid Species Binodoxys indicus to Switch over to Alternative Host-complexes." Entomologia Generalis 25, no. 1 (2000): 53–66. http://dx.doi.org/10.1127/entom.gen/25/2000/53.

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Veselý, Vojtech. "Robust decentralized switched controller design for linear continuous-time systems." Journal of Electrical Engineering 71, no. 4 (2020): 246–53. http://dx.doi.org/10.2478/jee-2020-0033.

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AbstractThe paper is devoted to obtain original equivalent subsystem method to design of decentralized controller for linear large scale systems. On the theoretical example a new robust decentralized PID switched controller design procedure is obtained for linear time-varying (gain scheduled plant model) uncertain complex system with decentralized output and input structure. Controller design procedure to decentralized controller design performs on the subsystem level. The designed decentralized switched controller ensures the robust stability of closed-loop complex polytopic system with perfo
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Boates, J. Sherman, and John D. Goss-Custard. "Foraging behaviour of oystercatchers Haematopus ostralegus during a diet switch from worms Nereis diversicolor to clams Scrobicularia plana." Canadian Journal of Zoology 67, no. 9 (1989): 2225–31. http://dx.doi.org/10.1139/z89-314.

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On the mudflats of the Exe Estuary in southwest England, oystercatchers Haematopus ostralegus switched from eating worms Nereis diversicolor to clams Scrobicularia plana during autumn. A decline in the profitability of worms (from 17 to 4 mg/s handling time) and the food intake of oystercatchers eating worms (from 1300 to < 200 mg/15 min) occurred prior to and during the switch to clams. Declines in profitability and food intake rate were due to seasonal changes in the size and food value of worms available to oystercatchers. Capture rate on worms varied little prior to, or during, the swit
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Grossoni, Ilaria, Louis M. Le Pen, Pedro Jorge, et al. "The role of stiffness variation in switches and crossings: Comparison of vehicle–track interaction models with field measurements." Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit 234, no. 10 (2019): 1184–97. http://dx.doi.org/10.1177/0954409719892146.

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The performance of switches and crossings compared with plain line is complicated by the presence of movable parts, changing rail geometry and non-uniformities in the composite and/or trackbed stiffness. These features lead to complex vehicle–track interactions and higher maintenance costs. The trackbed stiffness is the least well-controlled engineering property. A greater variability in trackbed stiffness leads to higher differential trackbed settlement and associated poorer track quality. At switches and crossings, changes in trackbed stiffness are exacerbated by changing rail properties whi
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Ito, Jun-ichi, Takahiro Ishihara, Takaki Fukuoka, Siti Rokiah Binti Mat Napi, Hajime Kameo, and Hisao Nishiyama. "Modulation of the coordination geometries of NCN and NCNC Rh complexes for ambidextrous chiral catalysts." Chemical Communications 55, no. 85 (2019): 12765–68. http://dx.doi.org/10.1039/c9cc06520b.

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Walker, Conor R., Aylwyn Scally, Nicola De Maio, and Nick Goldman. "Short-range template switching in great ape genomes explored using pair hidden Markov models." PLOS Genetics 17, no. 3 (2021): e1009221. http://dx.doi.org/10.1371/journal.pgen.1009221.

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Many complex genomic rearrangements arise through template switch errors, which occur in DNA replication when there is a transient polymerase switch to an alternate template nearby in three-dimensional space. While typically investigated at kilobase-to-megabase scales, the genomic and evolutionary consequences of this mutational process are not well characterised at smaller scales, where they are often interpreted as clusters of independent substitutions, insertions and deletions. Here we present an improved statistical approach using pair hidden Markov models, and use it to detect and describ
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Kroth, Elmar. "Switch – The German process for moving medicines from prescription to non-prescription status." Gesundheitsökonomie & Qualitätsmanagement 23, no. 02 (2017): 97–102. http://dx.doi.org/10.1055/s-0043-115561.

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Abstract Background Germany has a long tradition of switch and has long been considered one of the most liberal countries in terms of the release of modern active substances from prescription, the so-called switch. In the period 2000–2016, a total of more than 30 active ingredients – partly in different dosage strengths, dosage forms or indications – were released from prescription status in Germany. Of these, almost half can be described as “innovative” switches. Recently a significant decline of filed switch proposals can be noted, with only a few being successful. Methods Reflecting that th
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Yao, Kezi, Gogulan Karunanithy, Alison Howarth, et al. "Cell-permeable lanthanide–platinum(iv) anti-cancer prodrugs." Dalton Transactions 50, no. 25 (2021): 8761–67. http://dx.doi.org/10.1039/d1dt01688a.

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Lysenko, Igor E., Alexey V. Tkachenko, Olga A. Ezhova, and Boris G. Konoplev. "The modeling design integral the electrostatic microelectromechanical switch of capacitive type." ITM Web of Conferences 30 (2019): 06005. http://dx.doi.org/10.1051/itmconf/20193006005.

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This article presents the optimization and static modeling of the design an integral microelectromechanical switch of capacitive type based on a parametric 3D model using finite element analysis software complex ANSYS. The values of the pull-down voltage and switching time are determined. The obtained results give a good theoretical help in the development of various high-performance electrostatic microelectromechanical switches.
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Mohd, Esa. "Study and Simulation of Seven Level - Ten Switch Inverter Topology." International Journal of Research 8, no. 1 (2020): 798–803. https://doi.org/10.5281/zenodo.3757696.

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Compared to conventional two-level inverter, multilevel inverter performance is high because of their reduced harmonic distortion, less electromagnetic interference, reduced common mode voltage and higher dc link voltages. However complex pulse width modulation control, balancing of capacitor voltages & increased number of switches are main drawbacks of multilevel inverter.This paper focuses on study and simulation of single phase seven level inverter topology using only ten switches. This paper also presents two different control techniques for seven level-ten switch inverter topology.Rlo
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Zhao, Chen Xu, Xin Guo, Tao Deng, Ling Li, and Ze Wen Liu. "Automated and Optimal Actuation Voltage Waveform Design for Contact Bouncing Mitigation of MEMS Switches." Key Engineering Materials 609-610 (April 2014): 1248–53. http://dx.doi.org/10.4028/www.scientific.net/kem.609-610.1248.

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This paper presents an efficient methodology for automated optimal tailoring actuation voltage waveform of MEMS switches aiming at eliminating the detrimental contact bouncing effect to speed up the switching process and improve the mechanical reliability. This is a simulation-based approach where genetic algorithm (GA) is used in combination with a dedicated mechanical model of MEMS switch to derive optimal actuation waveform. The proposed technique has been implemented in SystemC-A, which is extremely well suited for complex modeling, implementation of post-processing of simulation results a
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Mee, Roger B. B. "Results of the arterial switch procedure for complete transposition with an intact ventricular septum." Cardiology in the Young 1, no. 1 (1991): 97–98. http://dx.doi.org/10.1017/s1047951100000159.

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With the general acceptance that the arterial switch operation represents the surgical treatment of choice for complex complete transposition, an increasing number of centers are leaning towards favoring this approach for simple transposition as well. As the arterial switch procedure is a more difficult surgical procedure than the Mustard or Senning operation, the learning curve has been longer and more hazardous. Centers with large referral bases have, understandably, enjoyed a more concentrated exposure to the arterial switch operation, and are now achieving early rates of mortality as low a
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GROOTE, JAN FRISO, and BAS PLOEGER. "SWITCHING GRAPHS." International Journal of Foundations of Computer Science 20, no. 05 (2009): 869–86. http://dx.doi.org/10.1142/s0129054109006930.

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Switching graphs are graphs that contain switches. A switch is a pair of edges that start in the same vertex and of which precisely one edge is enabled at any time. By using a Boolean function called a switch setting, the switches in a switching graph can be put in a fixed direction to obtain an ordinary graph. For many problems, switching graphs are a remarkable straightforward and natural model, but they have hardly been studied. We study the complexity of several natural questions in switching graphs of which some are polynomial, and others are NP-complete. We started investigating switchin
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Cantoni, Silvia, Monica Carpenedo, Maria Gabriella Mazzucconi, et al. "Thrombopoietin Receptor Agonist (TPO-RA) Switch in Adult Primary Immune Thrombocytopenia (ITP) Patients: A Retrospective Collaborative Survey from 8 Italian Hematology Centers." Blood 126, no. 23 (2015): 3462. http://dx.doi.org/10.1182/blood.v126.23.3462.3462.

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Abstract Introduction. Availability of the 2 TPO-RAs Romiplostim (Rom) and Eltrombopag (El) offers an effective treatment option for primary ITP patients (pts). However, some pts are either not responsive or lose response - i.e. desired platelet (plt) count achieved but not sustained over time, or experience wide fluctuations in plt count with either TPO-RA. Adverse events may cause treatment discontinuation. Finally, ptÕs preference may be an important issue considering the different route and timing of administration of the two agents. Availability of two TPO-RAs for clinical use, with diffe
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Gahley, Ruchi, and Banani Basu. "A Time Modulated Printed Dipole Antenna Array for Beam Steering Application." International Journal of Antennas and Propagation 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/3687293.

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This paper presents time modulated beam steered antenna array without phase shifters. The beam steering is analyzed considering a two-element time modulated antenna array (TMAA) of printed dipoles with microstrip via-hole balun. The proposed array resonates at the Industrial, Scientific, and Medical (ISM) radio bands, 2.45 GHz and 5.8 GHz, and offers wide bandwidth inherited due to modified structure of ground plane. Array elements are excited by complex exponential excitation signal through broadband power divider and radio frequency (RF) switches to achieve amplitude and phase variation with
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Cangelosi, Gerard A., Julie S. Do, Robert Freeman, John G. Bennett, Makeda Semret, and Marcel A. Behr. "The Two-Component Regulatory System mtrAB Is Required for Morphotypic Multidrug Resistance in Mycobacterium avium." Antimicrobial Agents and Chemotherapy 50, no. 2 (2006): 461–68. http://dx.doi.org/10.1128/aac.50.2.461-468.2006.

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ABSTRACT Clinical isolates of the opportunistic pathogen Mycobacterium avium complex (MAC) undergo a reversible switch between red and white colony morphotypes on agar plates containing the lipoprotein stain Congo red. Compared to their isogenic red counterparts, white morphotypic variants are more virulent and more resistant to multiple antibiotics. This report shows that the two-component regulatory system mtrAB is required for the red-to-white switch as well as for other morphotypic switches of MAC. A mutant with a transposon insertion in the histidine protein kinase gene mtrB was isolated
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Li, Longjie, Biao Wang, Chen Yi, Xianfeng Xu, Guimin Xu, and Yu Feng. "Factors and Underlying Mechanisms That Influence the Repetitive Breakdown Characteristics of Corona-Stabilized Switches." Applied Sciences 13, no. 17 (2023): 9518. http://dx.doi.org/10.3390/app13179518.

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The corona-stabilized switch has the potential to be a high repetition rate pulsed-power switching device, but there has been limited investigation into its repetitive breakdown stability and insulation recovery characteristics. Repetitive breakdowns of gas are characterized by a memory effect, where the subsequent breakdown process is inevitably influenced by the preceding one. However, there are still some issues that require further exploration in the current research on the mechanism of memory effect on repetitive breakdown characteristics. To clarify the factors and mechanisms that affect
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Percy, J. Joslin, S. Kanthamani, and S. Mohamed Mansoor Roomi. "Machine Learning-Driven Structural Optimization of a Bistable RF MEMS Switch for Enhanced RF Performance." Micromachines 16, no. 6 (2025): 680. https://doi.org/10.3390/mi16060680.

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In the rapidly advancing digital era, the demand for miniaturized and high-performance electronic devices is increasing, particularly in applications such as wireless communication, unmanned aerial vehicles, and healthcare devices. Radio-frequency microelectromechanical systems (RF MEMS), particularly RF MEMS switches, play a crucial role in enhancing RF performance by providing low-loss, high-isolation switching and precise signal path control in reconfigurable RF front-end systems. Among different configurations, electrothermally actuated bistable lateral RF MEMS switches are preferred for t
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