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1

Zisman, Natalia, Nancy Dos Santos, Sharon Johnstone, et al. "Optimizing Liposomal Cisplatin Efficacy through Membrane Composition Manipulations." Chemotherapy Research and Practice 2011 (January 24, 2011): 1–7. http://dx.doi.org/10.1155/2011/213848.

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The first liposomal formulation of cisplatin to be evaluated clinically was SPI-077. Although the formulation demonstrated enhanced cisplatin tumor accumulation in preclinical models it did not enhance clinical efficacy, possibly due to limited cisplatin release from the formulation localized within the tumor. We have examined a series of liposomal formulations to address the in vivo relationship between cisplatin release rate and formulation efficacy in the P388 murine leukemia model. The base formulation of phosphatidylcholine: phosphatidylglycerol: cholesterol was altered in the C18 and C16
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2

Okoye, J.I, A.C Nkwocha, and A.O Agbo. "NUTRIENT COMPOSITION AND ACCEPTABILITY OF SOY-FORTIFIED CUSTARD." Continental J. Food Science and Technology 2 (July 25, 2008): 37–43. https://doi.org/10.5281/zenodo.834652.

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The proximate composition and characteristics of custard formulation fortified with soybean flour were studied. The corn starch (CS) was composite with soybean flour (SF) at the levels of 10%, 20%, 305, 40% and 50%. The custard formulations prepared from the flour blends were evaluated for their proximate composition and sensory characteristics. Form the results, the protein content of the formulations increased steadily with increasing supplementation of soybean flour from 10.65% in 90:10 (CS : SF) to 17.16% in 50:50 (CS : SF) samples, while the carbohydrate decreased. Conversely, the energy
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3

Santosh, Payghan, Vaishali Kate, Sanjeevani Desai, Bhise Sandesh, Pradip Deshmukh, and Atul Deshmukh. "Composition of Lipid Based Nanoemulsion for Oral Delivery of Orlistat." Middle East Research Journal of Pharmaceutical Sciences 3, no. 06 (2023): 70–81. http://dx.doi.org/10.36348/merjps.2023.v03i06.001.

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Aim: The present work focused on to formulate, evaluate and optimize lipid based nanoemulsion of orlistat to enhance drug release. Materials and Methods: Nanoemulsion was prepared using Olive oil, Tween 80, and Distilled water as components. Lipid based nanoemulsion was evaluated for its pH, Rheology study, zeta potential, conductivity, particle size analysis, transmission electron microscopy (TEM) and stability. Central composite design was utilized for the optimization purpose. Formulation variables such as the concentration of Oil (ml) (X1) and Water (ml) (X2) were investigated for their ef
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4

Rahardjo, Monika, Kristiawan Prasetyo Agung Nugroho, and Greis Saibele. "Analisis fisik serta sensori kue kering dengan campuran tepung mocaf, oats, dan bekatul." Teknologi Pangan : Media Informasi dan Komunikasi Ilmiah Teknologi Pertanian 12, no. 2 (2021): 166–73. http://dx.doi.org/10.35891/tp.v12i2.2357.

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This research aims to analyze the physical and sensory characteristics of cookies’ formulations using mocaf-oats-rice bran’s flour mixture. Five formulations used in this research consist of mocaf-oats-rice bran’s flour mixture namely F1 (100%-0%-0%), F2 (70%-15%-15%), F3 (50%-25%-25%), F4 (30%-35%-35%), and F5 (0%-50%-50%). The result showed that all cookies formulation included in the category of “high fiber” except for cookies Formulation 4. The highest value of hardness was cookies Formulation 1 and significantly different from the other formulations. Decreasing mocaf flour composition in
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Abubakr, Adamu, Muhammed Yahuza, Abdulbaseet Umar, Atiku Muhammad, Mashi Jamila, and Shehu Dayyabu. "Potential Relevance of Allium sativum, Psidium Guajava Linn & Brassica oleracea Var. Capitata Formulations in the Management of Diabetes Mellitus." Alq J Med App Sci 6, no. 2 (2023): 451–59. https://doi.org/10.5281/zenodo.8239869.

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<strong>Background and aims.</strong> Diabetes mellitus (DM) is a significant global health concern and a leading contributor to mortality. It is characterized by both macrovascular and microvascular complications. Preventing the onset of diabetes and managing its associated complications are of utmost importance. In recent times, there has been a growing inclination towards the consumption of certain foods, driven by their recognized biological properties. The study aimed to evaluate the proximate composition and antioxidant vitamin content of formulations containing Allium sativum (garlic),
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N. Mayambala, Jane, and Edward Lambert. "GROWTH MEDIUM OPTIMIZATION AND GENETIC ADAPTATION OF A WILD EDIBLE AGARICUS MUSHROOM SPECIES IN UGANDA." International Journal of Advanced Research 12, no. 08 (2024): 1453–64. http://dx.doi.org/10.21474/ijar01/19390.

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In this study, experiments were carried out to optimize the growth medium of a selected wild edible Agaricus mushroom. The objectives of this study were to select the most popular edible Agaricus sp. sold in open food markets, and to determine the quantitative composition of the substrate formulation for optimal yield. The most popular species was found to be Agaricus bisporus and fresh samples were used to produce spawn for the experiments to determine the substrate quantitative composition, randomized complete design (RCD) was used. Molasses, chicken manure, and maize bran were varied in ten
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7

Milne, G. W. A. "Generic formulation of chemical composition." World Patent Information 13, no. 2 (1991): 76–80. http://dx.doi.org/10.1016/0172-2190(91)90006-q.

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8

Rawayau, A. M., M. K. Atiku, A. N. Ishaq, S. Abubakar, and U. A. Sabiu. "Proximate composition and functional analysis of some polyherbal formulations as potential botanical candidates for antidiabetic screening: A Preliminary study." Dutse Journal of Pure and Applied Sciences 8, no. 2a (2022): 140–48. http://dx.doi.org/10.4314/dujopas.v8i2a.15.

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Polyherbal formulations improve therapeutic action while lowering single herb concentration, thereby reducing possible side reactions. Proximate composition and functional properties of tomato, garlic, and carrot formulations were studied. Fresh samples of the botanicals were collected, identified and authenticated. Equal amount of each sample (500 g) was weighed, shed-dried and crushed into fine powdered particles. The proximate composition and functional properties of each formulation were determined according to a standard assay guideline. The result on proximate composition analysis reveal
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9

Mykhailyshyn, Bohdan, and Ivan Kuper. "Improving the formulation of hydraulic fracturing fluid." Prospecting and Development of Oil and Gas Fields 24, no. 1 (2024): 44–54. http://dx.doi.org/10.69628/pdogf/1.2024.44.

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The growing need to increase production of natural hydrocarbons makes hydraulic fracturing technology one of the key methods of production stimulation, so the need to improve the efficiency and cost-effectiveness of hydraulic fracturing, which can be achieved by optimising the fluid composition, is becoming an urgent issue. The aim of the study was to find effective formulations of hydraulic fracturing fluid that would have the structural and rheological properties necessary for successful hydraulic fracturing in wells with temperatures above 80°C. An empirical method of conducting laboratory
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10

Rahardjo, Monika, Ristia Widi Astuti, Dhanang Puspita, and Monang Sihombing. "Efek penambahan oats pada formulasi cookies gandum dilihat dari karakteristik fisik dan sensorinya." Teknologi Pangan : Media Informasi dan Komunikasi Ilmiah Teknologi Pertanian 11, no. 1 (2020): 1–6. http://dx.doi.org/10.35891/tp.v11i1.1714.

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This research aims to determine the effect of oats addition in wheat cookies formulation seen from physical and sensory characteristics. Six formulations used in this research consist of wheat flour and oats mixture namely Control (100%:0%), Formulation 1 (80%:20%), Formulation 2 (60%:40%), Formulation 3 (40%:60%), Formulation 4 (20%:80%), and Formulation 5 (0%:100%). Based on analysis of variance result at α = 5%, there was a significant difference in the value of hardness and work from control and all variation of cookies’ formulation. It was also found that the decreasing composition of whe
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11

K., F. Oyedeko*1 &. A. Onyieagho2. "EFFECT OF PROPELLANT FORMULATION ON PROPELLANT PROPERTIES." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 7, no. 8 (2018): 305–13. https://doi.org/10.5281/zenodo.1345623.

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This paper present the effect of propellant formulations on propellant properties is very crucial to the quality of propellant used in rocket motor. As poor propellant formulation usually leads to unstable combustion and this can lead to a total destruction of the entire structure of the solid rocket motor. For this research work, the centre compositions selected were based on calculation for percentage mass composition from the stoichiometric equation for the combustion process. Hollow bates grains used for the design consist of a mass of propellant of 6 kg, core diameter of 0.050m, throat di
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12

Khadijah, Babirye, and Abbas Kisambira. "Development, physico-chemical properties and proximate composition of maize based- soy milk." Pioneer Journal of Biostatistics and Medical Research 1, no. 3 (2024): 35–43. https://doi.org/10.61171/v01.03.24.

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Background: Lately, developing countries have directed their research endeavours to development of foods with a better protein quality by mixing legumes with cereals such that products attain a balanced nutritional quality. Objectives: To develop an acceptable plant milk which can replace cow’s milk, with a high protein content notably a balanced amino acid composition, evaluating its consumer acceptance through sensory evaluation, carrying out physico-chemical analysis and determination of the nutrient composition of both the most accepted blend of maize based-soy milk, and that of the formul
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13

Neverova, O., A. Koshchaev, O. Gorelik, P. Sharaviev, and E. Neverova. "Modeling of the cottage cheese products composition." IOP Conference Series: Earth and Environmental Science 949, no. 1 (2022): 012047. http://dx.doi.org/10.1088/1755-1315/949/1/012047.

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Abstract Combined food products provide the human body with all the necessary nutrients in a balanced amount. The paper presents a technique for modeling the formulation of semi-finished products from cottage cheese using the Excel program. The main components of semi-finished products are: cottage cheese of 5% fat content, flour from unsteamed buckwheat, egg melange. The goal of modeling was to obtain the optimal ratio of the components of the formulation, which meets the established requirements for indicators of nutritional value, as well as the recommended intake of vitamins and minerals f
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14

Corina Lai Hui Ling, Hasmadi Mamat, Ahmad Hazim Abdul Aziz, Mohd Khairi Zainol, and Norazlina Mohammad Ridwan. "Developing Healthier Biscuit Alternatives: An Analysis of Tapioca, Desiccated Coconut, and Wheat Flour Blends." International Journal of Food 1, no. 1 (2024): 1–10. http://dx.doi.org/10.51200/ijf.v1i1.4832.

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This study aimed to identify the optimal biscuit formulation using blends of tapioca flour, desiccated coconut flour and wheat flour. Four formulations, denoted as F1, F2, F3, and F4 with varying ratios of wheat flour, tapioca flour, and desiccated coconut flour (30:20:50, 30:30:40, 30:40:30, and 30:50:20 respectively), were produced. Multiple methodologies were employed to study the impact of composite flour on the quality of cookies, including sensory evaluation, proximate analysis, and physical evaluations. After a hedonic test involving 50 panelists, F3 emerged as the superior formulation.
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15

Rajesh, Akki* M.Gayatri Ramya M.Hymavathi P.Dinesh Kumar. "DEVELOPMENT, EVALUATION AND STABILITY OF ZOLEDRONIC ACID I.V INJECTION BY LYOPHILIZATION TECHNIQUE." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2042–46. https://doi.org/10.5281/zenodo.834723.

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The objective of the study is to develop a stable lyophilized formulation of Zoledronic acid for injection for better stability and for long term storage. The lyophilized product of all the formulations (F1- F6) prepared were an appearance of white to white Lyophilized cake. mannitol was used with water for injection . The filled vials were loaded into lyophilizer and lyophilized them as per cycle. Different composition of additives was used and the different pH concentrations of 5.7 to 6.7 were adjusted with sodium citrate were tried to formulate the formulation. The pH of all the formulation
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16

Garg, Naveen K., Antariksh Katara, and Mukul Mathur. "Formulation Development, Quality Evaluation and In VitroAntioxidant Activity of a Polyherboceutical Composition." International Journal of Pharmaceutical Sciences and Drug Research 13, no. 02 (2020): 190–96. http://dx.doi.org/10.25004/ijpsdr.2021.130212.

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Polyherbal preparations have been used for health management for decades. Allopathic dosage forms are prominent due to their ease of administration and stability, but polyherbal formulations are also pharmacologically effective and show useful therapeutic activity. As a result, extracts of a six potent herbs with anti-oxidant and anti-hypertensive properties were chosen and formulated in a capsule dosage form. This study aims to investigate the anti-oxidant activity of a polyherboceutical formulation. A polyherboceutical formulation were prepared using six ingredients, and quality control para
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17

Mohd, Hana, Katarzyna Dopierała, Anze Zidar, Amitkumar Virani, and Bozena Michniak-Kohn. "Effect of Edge Activator Combinations in Transethosomal Formulations for Skin Delivery of Thymoquinone via Langmuir Technique." Scientia Pharmaceutica 92, no. 2 (2024): 29. http://dx.doi.org/10.3390/scipharm92020029.

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Abstract: Thymoquinone (TQ), a bioactive compound found in Nigella sativa seeds, possesses diverse therapeutic properties for skin conditions. However, formulating TQ presents challenges due to its hydrophobic nature and chemical instability, which hinder its skin penetration. Transethosomes, as a formulation, offer an environment conducive to enhancing TQ’s solubility, stability, and skin permeation. To optimize TQ transethosomal formulations, we introduced a combination of ionic and nonionic surfactants, namely Tween 20 and sodium lauryl sulfate (SLS) or sodium lauroyl glutamate (SLG). Surfa
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18

Akhrorovich, Urinov Abrorbek. "FORMULATION DEVELOPMENT OF A NEW BITUMINOUS BUILDING COMPOUND." American Journal of Applied Sciences 5, no. 9 (2023): 19–24. http://dx.doi.org/10.37547/tajas/volume05issue09-04.

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The paper presents the results of comparative tests of physical and mechanical properties of experimental samples of construction bitumen composition in laboratory conditions. It is concluded that the experimental sample No11, obtained according to the formulation developed by the author, in comparison with other samples, allows to obtain a high-quality constructionbitumen composition. The developed construction bitumen composition is recommended to be used as a waterproofing material as a coating of foundations and building structures.
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19

Adesigbin, A.J., M.A. Adedeji, M.O. Oyeleke, and O.B. Ologunye. "Binding properties of starch and bentonite in the briquetting of fine particulate charcoal." European Journal of Advances in Engineering and Technology 5, no. 10 (2018): 782–90. https://doi.org/10.5281/zenodo.10726210.

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<strong>ABSTRACT</strong> The main objective of this study is to determine the possibility and to what extent the manufacture of briquettes from slack or charcoal fines may succeed commercially under the conditions existing in Nigeria. The need for Charcoal briquette is of utmost importance in this contemporary world. Data available on the binding properties of starch and bentonite in the briquetting of fine particulate charcoal is very limited. In this study different percentage compositions of the materials such as charcoal fine, sawdust, limestone, cassava starch, borax and bentonite were u
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20

Patil, Vishal, Radha Gupta, Rajendran D, and Ravinder Singh Kuntal. "COMPARATIVE STUDY ON FEED FORMULATION SOFTWARE- A SHORT REVIEW." International Journal of Research -GRANTHAALAYAH 5, no. 4RAST (2017): 105–15. http://dx.doi.org/10.29121/granthaalayah.v5.i4rast.2017.3311.

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The paper highlightsthe different feed formulation software’s for least cost formulation of livestock and animals, where the comparison of techniques is donebased on different aspectslike data collection, software used, price, scope and limitations. Feed formulation requires large amount of data about the composition of feeds, environment conditions,and availability of feeds.Development of Software’sfor feed formulations is changing with change in computer. With advancement of technology, the feed formulation can be calculated for ‘n’ number of feed stuff but still Linear Programming is used a
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Imangalieva, Zh K., N. K. Ibragimov, M. O. Kozhakhiyeva, and A. B. Yesenova. "OPTIMIZATION OF VITAMIN COMPOSITION IN CURD PRODUCTS." Mechanics and Technologies, no. 3 (September 30, 2024): 40–46. http://dx.doi.org/10.55956/yuxy9855.

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The research is devoted to the development of an optimal recipe for curd mass using information technology and linear programming methods. The method of calculating product characteristics based on the material balance and cost optimization was considered. It was revealed that the use of the “Minimax” software and the “Vitamax” module makes it possible to effectively optimize formulations and simulate the vitamin composition of products. It has been established that the creation of functional formulations of multicomponent products makes it possible to rationally use raw materials and expand t
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Aynalem, Elsabet Getachew, and Ramesh Duraisamy. "Formulation and Optimization of Complementary Food Based on Its Nutritional and Antinutritional Analysis." International Journal of Food Science 2022 (October 17, 2022): 1–7. http://dx.doi.org/10.1155/2022/1126031.

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This study focuses on formulating and optimizing complementary foods using oat, yellow maize, chickpea, avocado pulp powder, and sugarcane Jaggery to obtain nutritious infant food. Different proportions of the composite food were optimized using Minitab v.19 software upon mixture design by keeping the constant amount of Jaggery (10%). The formulated composite foods had a better proximate composition, minerals, vitamins, and lower amounts of antinutrients. Most attributes have shown significant differences ( p &lt; 0.05 ) among those formulations. The better-optimized formulation is selected fr
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23

Hamed, J. O., O. O. Ogunleye, and C. A. Osheku. "Optimal design of a composite propellant formulation using response surface methodology." Advances in Materials Science 17, no. 1 (2017): 44–57. http://dx.doi.org/10.1515/adms-2017-0004.

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Abstract There is a continuous demand for high performance composite propellant formulations to meet mission requirements. The performance of composite propellant formulations can be enhanced by optimizing propellant formulation. However, the main objective of this study is to formulate a composition for composite propellant by optimizing the specific impulse which is the measure of propellant performance. A central composite design (ccd) consisting five ingredients (ammonium nitrate, powdered aluminum, polyester resin, ammonium dichromate and powdered charcoal) at five levels was used to form
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Fironus Firdaus, Nurfarisha Ahmad, Mohd Hafizuddin Muhamad, Hassimi Abu Hasan, and Noorhisham Tan Kofli. "Bedak Padat daripada Penapaian Beras Menggunakan Teknik RSM." Jurnal Kejuruteraan 36, no. 6 (2024): 2403–13. http://dx.doi.org/10.17576/jkukm-2024-36(6)-14.

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Cooling powder is a traditional local cosmetic product produced from natural fermentation of rice. This product has been passed down until today due to its beneficial properties and is believed to have a cooling effect on the user. In current market, this product is still being sell in its traditional form which is in the form of powder and beads which are difficult to use. At the same time, there are concerns regarding safety talc-based cosmetics due to its potential contamination with asbestos, a toxic mineral. Therefore, this study is conducted to modernize this increasingly forgotten tradi
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Dabo, Khadija Florence, Christine Chèné, Anne-Laure Fameau, and Romdhane Karoui. "Whipping Creams: Advances in Molecular Composition and Nutritional Chemistry." Molecules 29, no. 24 (2024): 5933. https://doi.org/10.3390/molecules29245933.

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Whipping cream (WC) is an oil-in-water (O/W) emulsion used in food industry that can be transformed into aerated foam. The cream market has expanded significantly, driven by consumer demands for healthier and higher-quality products, leading to significant scientific research and innovation. This review focuses on formulation challenges related to ingredients such as fats, emulsifiers, and stabilizers, and how these components interact to form a stable emulsion and foam structure. Many studies have aimed to enhance the physicochemical, functional, and nutritional characteristics of WC by fine-
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26

Reznichenko, Irina, Tamara Renzyaeva, and A. Renzyaev. "Composition and Quality Standards of Functional Caramel." Food Processing: Techniques and Technology 50, no. 2 (2020): 204–11. http://dx.doi.org/10.21603/2074-9414-2020-2-204-211.

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Introduction. Functional foods help to improve the diet, maintain health, and prolong active longevity. Therefore, food science constantly develops new formulations of functional products. Caramel can hardly be called healthy food as it possesses low nutritional and high energy value. Moreover, caramel contains easily digested sugars but no physiologically functional ingredients, e.g. vitamins, minerals, etc. In order to increase the nutritional value of caramel, we fortified the traditional formulation with ascorbic acid and Valetek-3 vitamin premix. &#x0D; Study objets and methods. The resea
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27

Vishal, Patil, Gupta Radha, D. Rajendran, and Singh Kuntal Ravinder. "COMPARATIVE STUDY ON FEED FORMULATION SOFTWARE- A SHORT REVIEW." International Journal of Research - Granthaalayah 5, no. 4 (RAST) (2017): 105–15. https://doi.org/10.5281/zenodo.803466.

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The paper highlights the different feed formulation software’s for least cost formulation of livestock and animals, where the comparison of techniques is done based on different aspects like data collection, software used, price, scope and limitations. Feed formulation requires large amount of data about the composition of feeds, environment conditions, and availability of feeds. Development of Software’s for feed formulations is changing with change in computer. With advancement of technology, the feed formulation can be calculated for ‘n’ number of feed stuff but still Linear Programming is
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28

B. Lavanya Balakrishnan, Muthakana Vinod, Kokkiligadda Siddhartha, M. Nagarjuna, and R. Mohan Venkatesh. "Chemical Composition Analysis for Skincare Products." International Research Journal on Advanced Engineering Hub (IRJAEH) 3, no. 04 (2025): 1952–57. https://doi.org/10.47392/irjaeh.2025.0285.

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This project explores the use of t-Distributed Stochastic Neighbour Embedding (t-SNE) to visualize and analyze moisturizer products based on their ingredient compositions, specifically focusing on those designed for dry skin. The dataset includes detailed product labels, brands, prices, full lists of ingredients, and information about their suitability for different skin types. Ingredient information is transformed into a structured numerical representation using one-hot encoding, forming a document-term matrix (DTM) that maps ingredient presence across a wide range of products. Given the high
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Lee, Ye-Ji, and Joo-Eun Kim. "In Vitro–In Vivo Correlation of Tianeptine Sodium Sustained-Release Dual-Layer Tablets." Molecules 27, no. 9 (2022): 2828. http://dx.doi.org/10.3390/molecules27092828.

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Tianeptine tablets are currently marketed to be designed for immediate-release tablets. The tianeptine has a short half-life, making it difficult to design for sustained-release tablets and achieve bioequivalence with the tianeptine immediate-release tablet (Stablon®). We established the in vitro–in vivo correlation (IVIVC) of three formulations of tianeptine sustained-release tablets according to their granule size. To evaluate sustained drug release, in vitro tests were performed in pH 1.2 media for 24 h. In vivo pharmacokinetic analysis was performed following oral administration of referen
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P.K.V, Anand. "GC-MS PROFILING OF PHYTOCHEMICALS OF AN AYURVEDIC ANTI-HYPOTHYROID POLYHERBAL FORMULATION." International Journal of Advanced Research 10, no. 12 (2022): 821–27. http://dx.doi.org/10.21474/ijar01/15909.

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The therapeutic efficacy of Ayurveda medicine is time tested. Exploring the chemical composition of the formulations not only throws light into probable mode of action but may also lead the way to further drug discovery. Hence with the above objective an Ayurveda herbal composition effective in managing hypothyroidism was selected for GCMS to elucidate the phytochemicals present in it the formulation to gain insight into the probable bioactive principles. The methanolic extract of the Ayurveda formulation was subjected to mass spectrometry and the compounds were identified after comparing the
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Júnior, Jayme César da Silva, Ísis Meireles Mafaldo, Isabelle de Lima Brito, and Angela Maria Tribuzy de Magalhães Cordeiro. "Kombucha: Formulation, chemical composition, and therapeutic potentialities." Current Research in Food Science 5 (2022): 360–65. http://dx.doi.org/10.1016/j.crfs.2022.01.023.

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Ahmad, Aziz, Hesham Refaat, Sanghati Bhattacharya, et al. "Effect of formulation composition on trastuzumab stability." International Journal of Pharmaceutics 671 (February 2025): 125275. https://doi.org/10.1016/j.ijpharm.2025.125275.

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33

Umaru, Isaac John, Yakubu Ojochenemi Ejeh, Isaac Eleojo Shaibu, Agbo Christiana Onyindia, Prosper Uneju Peter, and Victor Duniya Sheneni. "Phytochemical and Mineral Composition of Triherbal Formulation." African Journal of Clinical Medicine and Pharmacy Research 2, no. 2 (2025): 283–95. https://doi.org/10.58578/ajcmpr.v2i2.5339.

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Herbal combinations are widely used for the treatment of various diseases in the developing countries. Their ability in boosting the immune system is a function of Mineral constituents present. Currently available drugs have been associated with number of side effects. Herbal Combinations have often been used in traditional medicine systems like Ayurveda, unani, African, Chinese Medicine, and Western herbalism. Combination of herbs is superior with increased therapeutic efficacy to individual herb. Triherbal combinations consisting of (Mucuna pruriens, Phyllantus amarus and Securidaca longiped
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Kim, Jong Hee, Seung Hyun Song, Sang Hoon Joo, Gyu Hwan Park, and Kwon-Yeon Weon. "Formulation of a Gastroretentive In Situ Oral Gel Containing Metformin HCl Based on DoE." Pharmaceutics 14, no. 9 (2022): 1777. http://dx.doi.org/10.3390/pharmaceutics14091777.

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A gastroretentive in situ oral gel containing metformin hydrochloride (Met HCl) was prepared based on sodium alginate (Sod ALG), calcium carbonate, and hydroxyethylcellulose (HEC). The optimal composition of the formulation was explored based on the design of experiments (DoE). First, a 32 full factorial design was used for formulation E1 to determine proper composition of Sod ALG and calcium carbonate. Second, a circumscribed central composite design was employed to add HEC as a thickening agent (formulation E2). The dissolution rates at 15, 30, 60, 120, and 240 min were used as responses. Pa
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Faujan, Nur Huda, Najeeba Azizan, and Norlelawati Arifin. "Proximate Composition and Sensory Preference of Beef Sausages with Unripe Jackfruit." Malaysian Journal of Science Health & Technology 8, no. 2 (2022): 9–13. http://dx.doi.org/10.33102/2022249.

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Underutilization of jackfruit and demand for healthier meat product with nutritional benefits and similar taste to meat had led to this study which to evaluate the proximate composition, and consumer preference of beef sausage with different ratio of unripe jackfruit. Five formulations of beef sausage were prepared with different amount of beef to unripe jackfruit were: Control (65:0), A (48.75:16.26), B (32.5:32.5), C (16.25:48.75), and D (0:65). Results found that carbohydrate contents of beef sausage with unripe jackfruit were higher (P&gt;0.05) than in control sausage but were lower (P&gt;
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Faujan, Nur Huda, Najeeba Azizan, and Norlelawati Arifin. "Proximate Composition and Sensory Preference of Beef Sausages with Unripe Jackfruit." Malaysian Journal of Science Health & Technology 8, no. 2 (2022): 9–13. http://dx.doi.org/10.33102/mjosht.v8i2.249.

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Underutilization of jackfruit and demand for healthier meat product with nutritional benefits and similar taste to meat had led to this study which to evaluate the proximate composition, and consumer preference of beef sausage with different ratio of unripe jackfruit. Five formulations of beef sausage were prepared with different amount of beef to unripe jackfruit were: Control (65:0), A (48.75:16.26), B (32.5:32.5), C (16.25:48.75), and D (0:65). Results found that carbohydrate contents of beef sausage with unripe jackfruit were higher (P&gt;0.05) than in control sausage but were lower (P&gt;
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Sayed-Ahmad, Bouchra, Martine Urrutigoïty, Akram Hijazi, et al. "Amaranth Oilseed Composition and Cosmetic Applications." Separations 9, no. 7 (2022): 181. http://dx.doi.org/10.3390/separations9070181.

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Amaranth (Amaranthus cruentus) is a possible alternative to high-nutritional-value crops. Amaranth seeds are considered to be one of the few sources of phytosqualene (up to 8%). The use of squalene and its hydrogenated form squalane in skincare formulations has been steadily increasing, and the demand for these compounds is expected to rise continuously. The aim of this study was to investigate the amaranth oilseed as a potential ingredient for cosmetic applications. First, an experimental design and optimization were carried out in order to obtain amaranth oil rich in squalane instead of squa
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Natalia, Omelchenko, Dmytrenko Viktoriia, Lysenko Natalia, Brailko Anna, and Martosenko Maryna. "DEVELOPMENT OF COMPOSITION FORMULATIONS, BASED ON NATURAL BISCHOFITE, TO PROTECT WOOD FROM FIRE." Eastern-European Journal of Enterprise Technologies 5, no. 10 (101) (2019): 31–41. https://doi.org/10.15587/1729-4061.2019.181305.

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We have studied the chemical composition of natural bischofite extracted from well No.&nbsp;1 at Zaturin deposit and revealed that the sufficient saturation of МgСl<sub>2</sub>&nbsp;allows its use as an environmentally-oriented base for composition formulations in order to protect wood from fire. Our experimental research has confirmed the efficiency of applying organic synthetic dyes (methyl orange, bromothymol blue) as coloring additives for the reported composition formulations. Technological features have been defined for using the pigment concentrates of trade marks&nbsp;&laquo;Amber&raqu
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Mardar, Marina, Natalia Tkachenko, Rafaela Znachek, and Larisa Agunova. "Simulation of formulation composition of the enriched spelt cereal products." Food Science and Applied Biotechnology 2, no. 2 (2019): 110. http://dx.doi.org/10.30721/fsab2019.v2.i2.68.

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The article deals with the simulation issues of the formulation composition of the enriched spelt crisp bread and green tea extract.&#x0D; The use of spelt and green tea extract as a raw material in the production of new functional crisp bread is substantiated. In order to optimize the formulation composition of new products, the response surface technique was used. Simulation and processing of experimental data was performed in the environment of Statistica 10software package (StatSoft, Inc.). On the basis of mathematical simulation methods the optimum mass fractions of green tea extract and
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Williams, Gifty, Maame Yaakwaah Adjei, Priscilla Ahadzi, et al. "Proximate Composition and Relative Preference Mapping of Milk Chocolate Emulsified with Okra Pectin." Journal of Science and Technology (Ghana) 42, no. 2 (2024): 62–75. http://dx.doi.org/10.4314/just.v42i2.5.

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In chocolate, the primary emulsifier used is soy lecithin. However, soy lecithin is a major allergen to some people and also considered expensive as it is imported. In this study, three different genotypes of okra pectin were extracted and used to replace lecithin in chocolate production as an emulsifier. The okra pectin samples were combined in different ratios and used in different chocolate formulations. The new formulations were evaluated by means proximate analysis and relative preference mapping (RPM). Results showed that there were no significant differences between the moisture content
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Kirgina, Maria, Maxim Maylin, Emilia Ivanchina, and Elizaveta Sviridova. "Optimization of High-Octane Gasoline Production." Advanced Materials Research 880 (January 2014): 121–27. http://dx.doi.org/10.4028/www.scientific.net/amr.880.121.

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The authors described a new approach to calculation of gasoline blending formulations taking into account the non-additivity of octane numbers and the composition of the raw materials with the use of the modeling system Compounding. Gasoline blending formulations developed for "Achinsk petroleum refinery" (Russia) meeting all environmental and technical standards. Applying the developed modeling system each refinery can choose necessary formulation of gasoline production taking into account composition and available flows. This will allow them to reduce the cost of gasoline and make the produc
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Mishra, Ina, Meredith Garrett, Stephen Curry, Jeffrey Jameson, and Michail Kastellorizios. "Effect of Composition and Size on Surface Properties of Anti-Cancer Nanoparticles." International Journal of Molecular Sciences 24, no. 17 (2023): 13417. http://dx.doi.org/10.3390/ijms241713417.

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Liposomal formulations offer significant advantages as anticancer drug carriers for targeted drug delivery; however, due to their complexity, clinical translation has been challenging. In addition, liposomal product manufacturing has been interrupted in the past, as was the case for Doxil® (doxorubicin hydrochloride liposome injection). Here, interfacial tension (IFT) measurements were investigated as a potential physicochemical characterization tool to aid in liposomal product characterization during development and manufacturing. A pendant drop method using an optical tensiometer was used to
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Amin, Azriszul Mohd, Mohd Halim Irwan Ibrahim, Rosli Asmawi, and Najwa Mustapha. "The Influence of Sewage Fat Composition on Rheological Behavior of Metal Injection Moulding." Applied Mechanics and Materials 660 (October 2014): 38–42. http://dx.doi.org/10.4028/www.scientific.net/amm.660.38.

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Influence of sewage ratio or Fat Oil Grease (FOG) on the feedstock rheological characteristic for optimal binder formulation in metal injection moulding is evaluated besides Polypropylene (PP) as a backbone binder. Powder loading of 62% of water atomised SS316L being used here to determine the possibility of the best binder formulation which could be optimised for optimal powder loading base on rheological characteristic analysis. Two binder formulations of PP to SF being selected here are 60/40, 50/50 and 40/60 accordingly with the powder loading of 62% each binder formulation. The analysis w
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Christos, Revelo Eved, Anastasia Hartanti, and Dionysius Subali. "The Potential of Mycofoam as a Biocomposite Material with Various Substrate and Mushroom Compositions." Jurnal Sumberdaya Hayati 10, no. 1 (2024): 7–14. http://dx.doi.org/10.29244/jsdh.10.1.7-14.

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Mycofoam is a biocomposite composed of mycelial filaments that bind to the host substrate, which can replace polystyrene. This research aims to determine the most appropriate formulation of the growing medium and mushroom to be used in mycofoam products based on some parameters. Composition is one of the main factors for selecting the most appropriate mycofoam to replace polystyrene. On the other hand, the quality of mycofoam can be assessed through its strength and water resistance. The mushroom mycelium used in this study came from Pleurotus ostreatus and Lentinula edodes. Besides, the growi
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Vijaya Bhaskar Reddy, Gudapureddy, Pidugu Amaravathi, Bhaskar Ganguly, Arub Ratan Sen, and Bandaru Venkata Vivekananda Reddy. "The effect of herbal supplements on the carcass characteristics, fatty acid profile and meat quality attributes of broilers." Veterinarski arhiv 93, no. 4 (2023): 447–62. http://dx.doi.org/10.24099/vet.arhiv.1759.

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The present investigation was carried out to determine the effect of two herbal formulations, AV/LMP/10 (T1) (garlic, Allium sativum) and AV/HLP/16 (T2) (mixture of gugal, Commiphora mukul and fenugreek, Trigonella foenum-graecum with 50:50%), on the carcass characteristics, proximate composition, lipid profile including fatty acids, and meat quality attributes in Vencobb 400 broiler chickens. Broilers fed with the AV/HLP/16 (T2) formulation had significantly (P&lt;0.05) superior carcass characteristics in terms of pre-slaughter weight, head, neck, shank, skin, stomach, intestine, giblet, and
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Guzmán, Romel, Juieta Gómez, and Samuel Chocrón. "Potential use of Sesame (Sesamum indicum L.) oil and sesame oil cake in the development of spreadable cocoa cream." American Journal of Food Sciences and Nutrition 2, no. 1 (2021): 1–11. http://dx.doi.org/10.47672/ajfsn.506.

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Global trends in food in recent years indicate a marked interest of consumers towards certain foods, which, in addition to the nutritional value, provide benefits to the physiological functions of the human body. Sesame seeds (variety DV-9) was used for the formulation of cocoa-based spread products with partial addition of sesame oil and sesame oil cake. Physical characterization and chemical composition of raw materials and formulation were performed. The formulations presented rheological behaved like non-Newtonian fluids. F4 as thixotropic fluid and F2; F3; F5 as Bingham plastics. All form
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Soloviev, Mikhail, Sergey Baldaev, Lev Baldaev, and Viktoriya Mischenko. "Site composition calculation for gas-thermal powder coating." Science intensive technologies in mechanical engineering 2022, no. 12 (2022): 38–43. http://dx.doi.org/10.30987/2223-4608-2022-12-38-43.

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The problem of choosing the optimal site composition formulation for gas-thermal powder coatings is viewed. A method for choosing a rational site composition formulation with given components parts by volume is proposed
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D’Souza, Susan, Jabar A. Faraj, Stefano Giovagnoli, and Patrick P. DeLuca. "Preparation, Characterization, and In Vivo Evaluation of Olanzapine Poly(D,L-lactide-co-glycolide) Microspheres." Journal of Pharmaceutics 2013 (August 12, 2013): 1–9. http://dx.doi.org/10.1155/2013/831381.

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The aim of this study was to prepare injectable depot formulations of Olanzapine using four poly(D,L-lactide-co-glycolide) (PLGA) polymers of varying molecular weight and copolymer composition, and evaluate in vivo performance in rats. In vivo release profiles from the formulations were governed chiefly by polymer molecular weight and to a lesser extent, copolymer composition. Formulations A and B, manufactured using low molecular weight PLGA and administered at 10 mg/kg dose, released drug within 15 days. Formulation C, prepared from intermediate molecular weight PLGA and administered at 20 m
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Poddar, Shives. "RAPID DISSOLUTION: DEVELOPMENT AND ASSESSMENT OF A NOVEL DRUG FORMULATION." American Journal of Medical Sciences and Pharmaceutical Research 06, no. 05 (2024): 01–05. http://dx.doi.org/10.37547/tajmspr/volume06issue05-01.

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This study focuses on the development and assessment of a novel fast-dissolving drug formulation aimed at improving drug delivery efficiency and patient compliance. The formulation was designed to dissolve rapidly in the oral cavity, facilitating quick absorption and onset of action. Through a systematic approach, the formulation's composition, including excipients and active pharmaceutical ingredients, was optimized to achieve rapid dissolution while maintaining stability and bioavailability. Various techniques, such as direct compression, freeze-drying, and spray drying, were explored to pro
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Nashed, Nour, Stephanie Chan, Matthew Lam, Taravat Ghafourian, and Ali Nokhodchi. "Effect of pH, Ionic Strength and Agitation Rate on Dissolution Behaviour of 3D-Printed Tablets, Tablets Prepared from Ground Hot-Melt Extruded Filaments and Physical Mixtures." Biomedicines 11, no. 2 (2023): 375. http://dx.doi.org/10.3390/biomedicines11020375.

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With the current focus on 3D-printing technologies, it is essential to understand the processes involved in such printing methods and approaches to minimize the variability in dissolution behaviour to achieve better quality control outcomes. For this purpose, two formulations of theophylline tablets were prepared using hydroxypropyl cellulose (HPC) and ethyl cellulose (EC). Among the two types of tablets, three different methods (physical mixture (PM), hot-melt extrusion (HME) and 3D-printing fused deposition modelling (FDM)) were applied and their dissolution behaviours were studied under var
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