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Dissertations / Theses on the topic 'Compound action potential'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 February 2022

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1

Murnane, Owen D., Beth A. Prieve, and Evan M. Relkin. "Recovery of the Human Compound Action Potential Following Prior Stimulation." Digital Commons @ East Tennessee State University, 1998. https://dc.etsu.edu/etsu-works/1793.

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The recovery from prior stimulation of the compound action potential (CAP) was measured using a forward masking stimulus paradigm in four normal-hearing, human subjects. The CAP was recorded using a wick electrode placed on the tympanic membrane. The effects of a 4000-Hz, 97-dB SPL conditioning stimulus on CAP amplitude in response to a 4000-Hz probe were measured as a function of conditioner–probe interval for three probe levels. The normalized probe response amplitude was completely recovered to the control values at an average conditioner–probe interval of 1359 ms, similar to that observed

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2

Jiang, Dan. "Cochlear compound action potential and pathology following kanamycin ototoxity in the guinea pig." Thesis, Keele University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359039.

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3

Novak, Kevin Richard. "EFFECTS OF SEPSIS ON NERVE EVOKED RESPONSES." Wright State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=wright1216123137.

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4

Schweinzger, Ivy A. "Examining the Physiologic Phenotype of Cochlear Synaptopathy Using Narrowband Chirp-Evoked Compound Action Potentials." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1573811742950316.

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5

Linke, Theresa [Verfasser], Uwe [Gutachter] Baumann, and Andreas [Gutachter] Bahmer. "On the relation of electrophysiological compound action potential (ECAP) measurements and perceptive skills in cochlear implant (CI) listeners / Theresa Linke ; Gutachter: Uwe Baumann, Andreas Bahmer." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2017. http://d-nb.info/1139358650/34.

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6

Chiou, Li-Kuei. "The effect that design of the Nucleus Intracochlear Electrode Array and age of onset of hearing loss have on electrically evoked compound action potential growth and spread of excitation functions." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/3060.

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The purpose of this study was to investigate how design changes in Cochlear Nucleus cochlear implants (CIs) (CI24M, CI24R, CI24RE and CI422) affected electrode impedance and ECAP measures, and to determine if these design changes affected post-lingually deafened adults and children with congenital hearing loss in a similar way. Results of this study showed that electrode impedance was inversely related to the area of the electrode contacts in the array: lowest for the full-banded CI24M CI and highest for adults who used the CI422 device which has the smallest electrode contacts of all four dev

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7

Scheperle, Rachel Anna. "Relationships among peripheral and central electrophysiological measures of spatial / spectral resolution and speech perception in cochlear implant users." Diss., University of Iowa, 2013. https://ir.uiowa.edu/etd/5055.

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The ability to perceive speech is related to the listener's ability to differentiate among frequencies (i.e. spectral resolution). Cochlear implant users exhibit variable speech perception and spectral resolution abilities, which can be attributed at least in part to electrode interactions at the periphery (i.e. spatial resolution). However, electrophysiological measures of peripheral spatial resolution have not been found to correlate with speech perception. The purpose of this study was to systematically evaluate auditory processing from the periphery to the cortex using both simple and spec

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8

Brown, Daniel. "Origins and use of the stochastic and sound-evoked extracellular activity of the auditory nerve." University of Western Australia. Dept. of Physiology, 2007. http://theses.library.uwa.edu.au/adt-WU2008.0082.

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[Truncated abstract] The present study investigated whether any of the characteristics of the compound action potential (CAP) waveform or the spectrum of the neural noise (SNN) recorded from the cochlea, could be used to examine abnormal spike generation in the type I primary afferent neurones, possibly due to pathologies leading to abnormal hearing such as tinnitus or tone decay. It was initially hypothesised that the CAP waveform and SNN contained components produced by the local action currents generated at the peripheral ends of the type I primary afferent neurones, and that changes in the

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9

La, Rocca Viviana. "Atividade antinociceptiva do geraniol: estudos comportamentaise eletrofisiológicos." Universidade Federal da Paraíba, 2016. http://tede.biblioteca.ufpb.br:8080/handle/tede/9944.

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Submitted by Leonardo Cavalcante (leo.ocavalcante@gmail.com) on 2018-07-17T18:53:07Z No. of bitstreams: 1 Arquivototal.pdf: 3232624 bytes, checksum: 559aa25bbe9205467b3fdd737354219e (MD5)<br>Made available in DSpace on 2018-07-17T18:53:07Z (GMT). No. of bitstreams: 1 Arquivototal.pdf: 3232624 bytes, checksum: 559aa25bbe9205467b3fdd737354219e (MD5) Previous issue date: 2016-02-29<br>The high incidence of pain in the general population has encouraged research about this theme. Products derived from plant species have been widely used in the pharmacological treatment of pain relief. Recent st

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10

Dhuldhoya, Aayesha Narayan. "Characterization of Temporal Interactions in the Auditory Nerve of Adult and Pediatric Cochlear Implant Users." Diss., University of Iowa, 2013. https://ir.uiowa.edu/etd/4838.

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Current cochlear implant systems use fast pulsatile stimulation to deliver the temporal modulations of speech and to, potentially, improve the neural representation of such modulations by restoring the independence of neural firing. The realization of these benefits may vary with other pulse rate-dependent temporal interactions that occur at the neural membrane, e.g., per(i)stimulatory adaptation and its post-stimulatory or forward masking effects. This study attempted to characterize adaptation and recovery of the electri

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11

Batrel, Charlène. "Nouvelle méthode d'exploration fonctionnelle du nerf auditif." Thesis, Montpellier 1, 2014. http://www.theses.fr/2014MON13520/document.

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Contexte: La réponse synchrone des fibres auditives, évaluée à partir de l'onde I des potentiels d'action évoqués auditifs (PEA), ou à partir du potentiel d'action composite (PAC) du nerf auditif, est l'élément clé du dépistage des neuropathies auditives. De récentes études ont toutefois montré que le seuil et l'amplitude de cette réponse pouvaient être absolument normaux malgré une perte importante de fibres du nerf auditif. Dans ce travail de thèse, nous proposons une nouvelle méthode d'exploration fonctionnelle, potentiellement applicable à l'homme, rendant mieux compte du nombre et de l'in

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12

Connors, Sean P. "Compounds that prolong the cardiac action potential." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670306.

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13

Botros, Andrew Computer Science &amp Engineering Faculty of Engineering UNSW. "The application of machine intelligence to cochlear implant fitting and the analysis of the auditory nerve response." Awarded By:University of New South Wales. Computer Science & Engineering, 2010. http://handle.unsw.edu.au/1959.4/44707.

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Effective cochlear implant fitting (or programming) is essential for providing good hearing outcomes, yet it is a subjective and error-prone task. The initial objective of this research was to automate the procedure using the auditory nerve electrically evoked compound action potential (the ECAP) and machine intelligence. The Nucleus?? cochlear implant measures the ECAP via its Neural Response Telemetry (NRT) system. AutoNRT, a commercial intelligent system that measures ECAP thresholds with the Nucleus Freedom implant, was firstly developed in this research. AutoNRT uses decision tree expe

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14

Xu, Ying. "Antifouling compounds from deep-sea bacteria and their potential mode of action /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202009%20XU.

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15

Iyer, Chitra C. "The Role of Muscle and Nerve in Spinal Muscular Atrophy." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1451568269.

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16

Donato, Micheline Freire. "Purificação, caracterização bioquímica e eletrofisiológica da toxina Mic6c7NTX da Peçonha da Serpente Micrurus ibiboboca (Merrem, 1820)." Universidade Federal da Paraíba, 2008. http://tede.biblioteca.ufpb.br:8080/handle/tede/6863.

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Made available in DSpace on 2015-05-14T13:00:16Z (GMT). No. of bitstreams: 1 parte1.pdf: 4104748 bytes, checksum: 578975146349baff07079d6c3f9756b6 (MD5) Previous issue date: 2008-08-29<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>Snake venoms contain a complex arsenal of protein bio-active components, many of these being neurotoxins (NTXs). These snakes have high neurotoxic activity venom, corresponding to the Elapidae family, which includes coral snakes (Micrurus) whose venom contains circa 90-95% of low molecular mass protein components. Among these, seve

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17

Stengel, Chloe. "Investigation of the mechanisms of action of sulphamoylated compounds, a potential new class of drug to treat cancer." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506928.

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18

Radford, Michael T. "A study of Central Florida nonroad VOC and NOx emissions and potential actions to reduce emissions." Orlando, Fla. : University of Central Florida, 2009. http://purl.fcla.edu/fcla/etd/CFE0002850.

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19

Berezina, Maria Andrey. "Medial olivocochlear efferent (MOC) effects on stimulus frequency otoacoustic emissions (SFOAEs) and auditory-nerve compound action potentials (CAP) in guinea pigs." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/97822.

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Thesis: Ph. D., Harvard-MIT Program in Health Sciences and Technology, February 2015.<br>Cataloged from PDF version of thesis. "February 2015."<br>Includes bibliographical references.<br>In humans, SFOAEs can non-invasively assess MOC strength and, may predict the MOC reduction of damage from traumatic sounds. However, the functionally important MOC effect is inhibition of auditory-nerve (AN) responses. Understanding the relationship between MOC effects on SFOAEs and AN CAPs is important for understanding SFOAE generation and for development of clinical tools that use these measures. This thes

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20

Bouarab, Lynda. "Évaluation du potentiel et de voies innovantes de mise en oeuvre de composés phénoliques antimicrobiens d’origine végétale pour la conservation des aliments." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSE1084.

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Le règne végétal est une ressource renouvelable d'une large gamme de métabolites secondaires biologiquement actifs. Ces travaux de thèse proposent une stratégie multidisciplinaire d'évaluation du potentiel de composés phénoliques antimicrobiens d'origine végétale pour la conservation des aliments. Un criblage de l'activité antimicrobienne in vitro vis-à-vis de 8 souches de la flore pathogène et d'altération des aliments d'une centaine de molécules pures et une soixantaine d'extraits végétaux a d'abord permis de sélectionner les plus actifs. Différents mécanismes d'action vis-à-vis de S. aureus

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21

Zhang, Jiaxin. "Syntheses and spectroscopic studies of luminescent surfactant rhenium(I) and ruthenium(II) diimine complexes : potential applications as functional materials for second-harmonic generation and mesoporous silicate formation /." View the Table of Contents & Abstract, 2004. http://sunzi.lib.hku.hk/hkuto/record/B30267791.

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22

Zhang, Jiaxin, and 張家新. "Syntheses and spectroscopic studies of luminescent surfactant rhenium(I) and ruthenium(II) diimine complexes: potential applications as functional materials forsecond-harmonic generation and mesoporous silicate formation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B45015272.

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23

Yaacoubi, Abdelrani. "Etude de l'influence d'ions metalliques et de composes organiques sur l'adsorption du dodecyl sulfate de sodium sur charbon actif." Poitiers, 1988. http://www.theses.fr/1988POIT2286.

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Les resultats experimentaux (cinetique rapide d'adsorption, parametre d'equilibre des isothermes d'adsorption et variation du potentiel zeta des particules de charbon) montrent une augmentation de la capacite d'adsorption du dodecylsulfate de sodium en presence d'ions metalliques et une inhibition mutuelle de l'adsorption en presence d'alcools aliphatiques et de composes organiques

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24

Esvan, Yannick. "Conception et synthèse de nouveaux composés hétéroaromatiques inhibiteurs potentiels de kinases." Thesis, Clermont-Ferrand 2, 2016. http://www.theses.fr/2016CLF22743.

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Depuis la mise en évidence de l’existence des protéines kinases vers la fin des années 1950 cette famille d’enzymes s’est vu attribuer d’importants rôles dans divers mécanismes pathologiques notamment dans des processus de cancérisations. Plus récemment ces enzymes ont été identifiées comme potentiellement impliquées dans d’autres types de maladies telles que les maladies neurodégénératives.Deux projets de recherche seront présentés. Le premier projet expose la conception et la synthèse de nouveaux composés tricycliques de la famille des pyrido[3,4-g]quinazolines. Les propriétés inhibitrices d

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25

Souabi, Salah. "Etude de l'adsorption de tensioactifs cationiques sur charbon actif influence de coadsorbats /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376186543.

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26

Wang, Shao-Po, and 王韶博. "Modeling Evoked Compound Action Potential and Signal Processing in Cochlear Implant." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/51585449622758054259.

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碩士<br>義守大學<br>電機工程學系<br>91<br>ABSTRACT A prosthetic device, called the cochlear implant, can be implanted in the inner ear and can restore partial hearing to profoundly deaf people. According to the clinical data, the effect is vary different from individual. Therefore, improved efficacy to cochlear implant is such a important work. There are two ways can ameliorate the situation. One is to find the new stimulation strategy, the other is to design new electrode dimension over again. When new stimulation strategy or new electrode be developed. Apply to patient is only way to distin

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27

Huang, Hau-Shiou, and 黃浩修. "Patient-specific Models based on Evoked Compound Action Potential and Electrical Field Imaging." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/67049380601925852684.

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碩士<br>國立交通大學<br>生醫工程研究所<br>105<br>With physiological dimensions of the cochlear implant (CI) patient’s cochlea from computed tomography (CT), it is possible to build a more accurate patient-specific electro-neural model of CI patients based on clinical measurements. One of such methods is proposed in this thesis. An accurate patient specific electro-neural model could be used for fine tuning the electrical stimulation parameters or “maps” of a CI patient without needing many CI mapping sessions. This has enormous implication for CI pediatric applications due to obvious reason. The goal of thi

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28

LI, ZHI-CHANG, and 李志昌. "Morphological organization and compound action potential of sacrococcygeal dorsal roots of the rat." Thesis, 1991. http://ndltd.ncl.edu.tw/handle/88921030062421954300.

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29

ZHAO, FU-SHAN, and 趙福杉. "Analysis of compound action potential and field potential of the nervous syste, and development of a recording system." Thesis, 1992. http://ndltd.ncl.edu.tw/handle/20147015298986728414.

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30

Muzquiz, Maria I. "Reversible Nerve Conduction Block Using Low Frequency Alternating Currents." Thesis, 2020. http://hdl.handle.net/1805/23576.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>This thesis describes a novel method to reversibly and safely block nerve conduction using a low frequency alternating current (LFAC) waveform at 1 Hz applied through a bipolar extrafascicular electrode. This work follows up on observations made on excised mammalian peripheral nerves and earthworm nerve cords. An in-situ electrophysiology setup was used to assess the LFAC waveform on propagating action potentials (APs) within the cervical vagus nerve in anaesthetized Sprague-Dawley rats (n = 12). Two sets of bipolar cuff or hook elec

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31

Candeias, Rui Dinis Teodoro. "Evaluation of motor neuron excitability by CMAP scanning with modulated current." Master's thesis, 2014. http://hdl.handle.net/10362/14288.

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It is important to have better evaluation and understanding of the motor neuron physiology, with the goal to early and objectively diagnose and treat patients with neurodegenerative pathologies. The Compound Muscle Action Potential (CMAP) scan is a non-invasive diagnosis technique for neurodegenerative pathologies, such as ALS, and enables a quick analysis of the muscle action potentials in response to motor nerve stimulation. This work aims to study the influence of different pulse modulated waveforms in peripheral nerve excitability by CMAP scan technique on healthy subjects. A total of 13

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32

Lo, Tun-Shin, and 羅敦信. "Efficacy of electrically evoked auditory brainstem response and electrically evoked compound action potential in programming children with the Nucleus-24 Cochlear Implants." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/75360032289540431241.

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碩士<br>國立台北護理學院<br>聽語障礙科學研究所<br>92<br>Several reports have shown the benefit in speech perception of cochlear implants. Determination of behavioral threshold levels (T-levels) and comfort levels (C-levels) of the cochlear implant users is very important for their performance of auditory perception. Either electrically evoked compound action potential (ECAP) or electrically evoked auditory brainstem response (EABR) has been studied to help with optimizing individual’s map parameters of cochlear implant users, particularly young children, in whom accurate behavioral T-levels and C-levels to elect

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33

Syu, Ruei-Syuan, and 許睿軒. "The Design of CMOS Analog Front-End Acquisition Circuits for Electrocorticography (ECoG) and Evoked Compound Action Potential (ECAP) Recording in Implantable Medical Devices." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/xd928n.

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34

Kent, Alexander Rafael. "Characterization of Evoked Potentials During Deep Brain Stimulation in the Thalamus." Diss., 2013. http://hdl.handle.net/10161/8195.

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<p>Deep brain stimulation (DBS) is an established surgical therapy for movement disorders. The mechanisms of action of DBS remain unclear, and selection of stimulation parameters is a clinical challenge and can result in sub-optimal outcomes. Closed-loop DBS systems would use a feedback control signal for automatic adjustment of DBS parameters and improved therapeutic effectiveness. We hypothesized that evoked compound action potentials (ECAPs), generated by activated neurons in the vicinity of the stimulating electrode, would reveal the type and spatial extent of neural activation, as well as

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35

(9178664), Maria I. Muzquiz, and Ivette M. Muzquiz (9178658). "Reversible Nerve Conduction Block Using Low Frequency Alternating Currents." Thesis, 2020.

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This thesis describes a novel method to reversibly and safely block nerve conduction using a low frequency alternating current (LFAC) waveform at 1 Hz applied through a bipolar extrafascicular electrode. This work follows up on observations made on excised mammalian peripheral nerves and earthworm nerve cords. An<i> in-situ</i> electrophysiology setup was used to assess the LFAC<br>waveform on propagating action potentials (APs) within the cervical vagus nerve in anaesthetized Sprague-Dawley rats (n = 12). Two sets of bipolar cuff or hook electrodes were applied unilaterally to the cervical va

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36

Smit, Jacoba Elizabeth. "Modelled response of the electrically stimulated human auditory nerve fibre." Thesis, 2008. http://upetd.up.ac.za/thesis/available/etd-09182008-144232/.

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37

Martins, Pedro Freire de Sousa. "Biological evaluation of chlorogold complexes as potential anti-tumoural compounds: unraveling mechanisms of action." Master's thesis, 2014. http://hdl.handle.net/10362/14061.

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Cytotoxic chemotherapyat the present state is set asthe traditional hallmark of oncological treatment;however host toxicity and drug resistance acquisition remainas main challengesto overcome.Over the past few years there has been a great effort towards findingnew chemotherapeutic compounds with improvedpharmacodynamic and pharmacokinetic properties in order to achieve higher cancer specificityandreducedundesirable side effects. The present work intendedtocharacterize andelucidate the anti-tumouraleffect of chlorogold complexes bearing phosphineor N,O-d

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38

Hsiu-Lien, Cheng, and 鄭秀蓮. "The comparison of cochlear traveling time in Meniere’s disease and normal hearing ears using derived-band cochlear compound action potentials and auditory brainstem responses." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/44926540443587003516.

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碩士<br>國立台北護理學院<br>聽語障礙科學研究所<br>96<br>Background: This study is designed for comparing the cochlear traveling time difference between ears of Meniere’s disease (MD) patients and normal subjects. Both derived-band auditory brainstem responses (ABRs) and compound action potentials (CAPs) detecting techniques were used. To improve the recognized waveform latencies, the CAP was detected by using the Biologic TM-EcochGtrode system electrodes. Derived-band technique was adopted and modified from previous literature by applying an ipsilateral high-pass masking noise. Material and Methods: This study r

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39

(9356939), Jui-wei Tsai. "Digital Signal Processing Architecture Design for Closed-Loop Electrical Nerve Stimulation Systems." Thesis, 2020.

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<div>Electrical nerve stimulation (ENS) is an emerging therapy for many neurological disorders. Compared with conventional one-way stimulations, closed-loop ENS approaches increase the stimulation efficacy and minimize patient's discomfort by constantly adjusting the stimulation parameters according to the feedback biomarkers from patients. Wireless neurostimulation devices capable of both stimulation and telemetry of recorded physiological signals are welcome for closed-loop ENS systems to improve the quality and reduce the costs of treatments, and real-time digital signal processing (DSP) en

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40

Effertz, Thomas. "Candidate mechanosensitive transduction channels in Drosophila melanogaster." Doctoral thesis, 2011. http://hdl.handle.net/11858/00-1735-0000-0006-AE0E-8.

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