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Relevant bibliographies by topics / Compound stability

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Academic literature on the topic 'Compound stability'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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Journal articles on the topic "Compound stability"

1

Blaxill, Zoe, Sue Holland-Crimmin, and Rob Lifely. "Stability Through the Ages: The GSK Experience." Journal of Biomolecular Screening 14, no. 5 (2009): 547–56. http://dx.doi.org/10.1177/1087057109335327.

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It is common knowledge in the pharmaceutical industry that the quality of a company's compound collection has a major influence on the success of biological screening in drug discovery programs. DMSO is the widely accepted solvent of choice for storage of compounds, despite the hygroscopic nature of the solvent, which can lead to stability issues. Other factors that can affect compound stability (e.g., degradation, precipitation) include concentration of compound, intrinsic compound stability, presence of reactive contaminants, storage format-related factors (vessel, sealing, etc.), storage co

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Cheng, Xueheng, Jill Hochlowski, Hua Tang, et al. "Studies on Repository Compound Stability in DMSO under Various Conditions." Journal of Biomolecular Screening 8, no. 3 (2003): 292–304. http://dx.doi.org/10.1177/1087057103008003007.

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The chemical stability of repository compounds is affected by various environmental conditions during long-term storage. Studies were carried out to evaluate the effects of the following potential causes of instability of compounds in DMSO at a 10-mM concentration: water, oxygen, freeze/thaw cycles, and storage container material. A set of compounds was selected for the study based on structural diversity and functional group representation. Compound concentration was determined with liquid chromatography/ultraviolet spectroscopy/mass spectrometry (LC/UV/MS) analysis relative to an internal st

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Yankin, A. M., L. B. Vedmid, O. M. Fedorova, and V. F. Balakirev. "Thermal stability of EuMnO3 compound." Bulletin of the Russian Academy of Sciences: Physics 75, no. 8 (2011): 1131–32. http://dx.doi.org/10.3103/s1062873811080417.

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Engeloch, Caroline, Ulrich Schopfer, Ingo Muckenschnabel, et al. "Stability of Screening Compounds in Wet DMSO." Journal of Biomolecular Screening 13, no. 10 (2008): 999–1006. http://dx.doi.org/10.1177/1087057108326536.

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The impact of storage conditions on compound stability and compound solubility has been debated intensely over the past 5 years. At Novartis, the authors decided to opt for a storage concept that can be considered controversial because they are using a DMSO/water (90/10) mixture as standard solvent. To assess the effect of water in DMSO stocks on compound stability, the authors monitored the purity of a subset of 1404 compounds from ongoing medicinal chemistry projects over several months. The study demonstrated that 85% of the compounds were stable in wet DMSO over a 2-year period at 4 °C. Th

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Słoczyńska, Karolina, Agnieszka Gunia-Krzyżak, Paulina Koczurkiewicz, et al. "Metabolic stability and its role in the discovery of new chemical entities." Acta Pharmaceutica 69, no. 3 (2019): 345–61. http://dx.doi.org/10.2478/acph-2019-0024.

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Abstract Determination of metabolic profiles of new chemical entities is a key step in the process of drug discovery, since it influences pharmacokinetic characteristics of therapeutic compounds. One of the main challenges of medicinal chemistry is not only to design compounds demonstrating beneficial activity, but also molecules exhibiting favourable pharmacokinetic parameters. Chemical compounds can be divided into those which are metabolized relatively fast and those which undergo slow biotransformation. Rapid biotransformation reduces exposure to the maternal compound and may lead to the g

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Bowes, Scott, Dongyu Sun, Azita Kaffashan, et al. "Quality Assessment and Analysis of Biogen Idec Compound Library." Journal of Biomolecular Screening 11, no. 7 (2006): 828–35. http://dx.doi.org/10.1177/1087057106290993.

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A subset of the compound repository for lead identification at Biogen Idec was characterized for its chemical stability over a 3-year period. Compounds were stored at 4 °C as 10 mM DMSO stocks, and a small subset of compounds was stored as lyophilized dry films. Compound integrity of 470 discrete compounds (Compound Set I) and 1917 combinatorial chemistry-derived compounds (Compound Set II) was evaluated by liquid chromatography/mass spectrometry from the time of acquisition into the library collection and after 3 years of storage. Loss of compound integrity over the 3 years of storage was obs

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Mousavi, Seiedeh Negar, Davood Nori-Shargh, Hooriye Yahyaei, and Kobra Mazrae Frahani. "Complete basis set, hybrid-density functional theory study, and natural bond orbital interpretations of the conformational behavior of halocarbonyl, thiocarbonyl, and selenocarbonyl isocyanates." Canadian Journal of Chemistry 90, no. 4 (2012): 333–43. http://dx.doi.org/10.1139/v2012-002.

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Complete basis set CBS-QB3, hybrid-density functional theory (B3LYP/Def2-TZVPP) based methods and NBO interpretation were used to investigate the impacts of the stereoelectronic effects and electrostatic and steric interactions on the conformational properties of halocarbonyl isocyanates (halo = F (1), Cl (2), and Br (3)), halothiocarbonyl isocyanates (halo = F (4), Cl (5), and Br (6)), and haloselenocarbonyl isocyanates(halo = F (7), Cl (8), and Br (9)). Both methods showed that the Z-conformations of compounds 1, 4, and 7 are more stable than their corresponding E conformations, but the stab

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Hasan, Alfaisal A. "Electrogravitational stability of streaming compound jets." International Journal of Biomathematics 09, no. 02 (2016): 1650032. http://dx.doi.org/10.1142/s1793524516500327.

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The electrohydrodynamic stability of a self-gravitating streaming compound jet has been investigated for all modes of perturbation. The jets are immersed in a dielectric motionless tenuous medium pervaded by varying electric field. A second-order integro-differential equation of Mathieu type has been derived and some reported works are recovered as limiting cases from it.

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Vedmid, L. B., A. M. Yankin, V. F. Balakirev, and O. M. Fedorova. "Thermal stability of the GdMnO3 compound." Glass Physics and Chemistry 41, no. 2 (2015): 244–46. http://dx.doi.org/10.1134/s1087659615020145.

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Zhang, Yazhuo, and Baodong Zheng. "The Stability Criteria with Compound Matrices." Abstract and Applied Analysis 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/930576.

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The bifurcation problem is one of the most important subjects in dynamical systems. Motivated by M. Li et al. who used compound matrices to judge the stability of matrices and the existence of Hopf bifurcations in continuous dynamical systems, we obtained some effective methods to judge the Schur stability of matrices on the base of the spectral property of compound matrices, which can be used to judge the asymptotical stability and the existence of Hopf bifurcations of discrete dynamical systems.

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Dissertations / Theses on the topic "Compound stability"

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Felix, Anabel. "Redox potential and metabolic stability : development of high throughput assays for early compound profiling /." [S.l.] : [s.n.], 2009. http://edoc.unibas.ch/diss/DissB_8746.

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Kusza, Daniel Andreas. "Mechanistic insights into the cancer cell cytotoxicity and blood stability of the garlic compound ajoene." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22989.

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Ajoene, a garlic-derived natural product and its structural analogues are strongly cytotoxic to cancer cells. These compounds are however known to exhibit low blood stability and erythrocyte toxicity. This thesis reports on the synthesis of eight ajoene analogues designed to probe structure-activity relations into cancer cell cytotoxicity and blood stability. Structural variations included introduction of different solubility enhancing terminal groups (amide and phenol) as well as variations in the sulfoxide / vinyl-disulfide core. The phenol ajoene analogues were found to be more cytotoxic ag

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Jabson, Ben. "The Effects of Wort Oxygenation Scenarios on Fermentation Performance, Volatile Flavor Compound Development, and Flavor Stability in High Gravity Brewing." DigitalCommons@CalPoly, 2021. https://digitalcommons.calpoly.edu/theses/2283.

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High gravity (HG) brewing has become the most used strategy for maximizing fermenter productivity in commercial brewing. While HG brewing has many benefits, the additional stress placed on the yeast due to the higher concentration of fermentable sugars in the wort can negatively impact fermentation performance and flavor compound formation. A proper dissolved oxygen (DO) level is vital to guarantee adequate yeast performance during HG fermentations. Dissolved oxygen is vital to yeast viability throughout the fermentation process, as yeast requires oxygen to synthesize vital cell membrane compo

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Chang, Hao Hsun. "Quantitative Changes of Volatile Compound in Soybean and Algal Oil and Effects of Antioxidants on the Oxidative Stability of Algal Oil under Light Storage." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1296496541.

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Zhou, Li. "Development of oxidation models and analytical techniques specific to phospholipids and their degradation products in functional foods." Phd thesis, Université de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-00804705.

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Among the numerous beneficial effects of phospholipides can highlight their role in protecting the cardiovascular system and improving memory and learning. These effects can be partially explained by the fact that phospholipids are rich in polyunsaturated (eicosapentaenoic and docosahexaenoic acids) or essential fatty acids. Thus, it is very significant to explore potential food sources containing polyunsaturated rich phospholipids for the development new food products supplemented with phospholipids.This work allowed a series method for the extraction, purification, separation and quantificat

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Gunella, Michel. "Equações de diferenças dinâmica cobweb e ajustes adaptativos." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/55/55136/tde-15022017-145017/.

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Quando um capital é alugado ou investido, uma parte age como o credor e o outro como o mutuário. O credor é o proprietário do capital e, como prêmio, o mutuário paga juros ao credor para o uso do capital do credor. Por exemplo, quando o dinheiro é depositado em uma conta poupança, o depositante é o credor e o banco é o mutuário. Este fenômeno gera uma dinâmica, este é o tema principal desta dissertação. Consideramos alguns modelos clássicos sob o ponto de vista das equações de diferenças, com ênfase no estudo da existência de um equilíbrio bem como as condições especiais para a sua estabilidad

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Gonzales, Veronica Lourdes Escobar. "Stability of calcium phosphate arsenate compounds." Thesis, Imperial College London, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341898.

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Carvalho, Joelia Marques de. "Virgin cashew nut oil (VCNO) and extra virgin cashew nut oil (EVCNO): processing, characterization, sensory evaluation and bioactivity." Universidade Federal do CearÃ, 2015. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=15334.

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A amÃndoa de castanha de caju (ACC) Ã um dos principais produtos do agronegÃcio cearense, mas tambÃm Ã fonte de renda para pequenos produtores rurais, principalmente nos perÃodos de estiagem. A amÃndoa de castanha de caju de maior valor para comercializaÃÃo Ã que aquela se classifica como inteira de primeira qualidade. As amÃndoas de castanha de caju de qualidade inferior, por cor ou quebradas durante o processamento, chegam a perder 80% do seu valor comercial. Desta forma, este trabalho teve como objetivo o desenvolvimento de um Ãleo a partir da amÃndoa de castanha de caju de classes inferior

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Darif, B. (Bouchra). "Synthesis and characterization of catalysts used for the catalytic oxidation of sulfur-containing volatile organic compounds:focus on sulfur-induced deactivation." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526214221.

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Abstract The work in this thesis concentrates on finding more active and durable catalysts for the demanding environmental application of the oxidation of sulfur-containing volatile organic compounds (S-VOCs). This application is challenging due to the high purification levels required and the catalyst deactivating nature of sulfur. In this thesis, dimethyldisulfide (DMDS) was used as the model molecule to represent S-VOCs since it is often present in odorous emissions and it is more difficult to treat than most of the other S-VOCs. It was found that the addition of a very small amount of Pt (

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Lafarge, Céline. "Impact du glucomannane de konjac sur les interactions composés volatils - amidon de pomme de terre dans un gel hydraté." Thesis, Dijon, 2016. http://www.theses.fr/2016DIJOS007/document.

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L’objectif de ce travail est de démontrer que la présence de glucomannane de konjac (KGM) dans une matrice d’amidon de pomme de terre permet d’accroître sa stabilité physique sans inhiber l’encapsulation moléculaire de composés d’arôme par l’amylose. Pour cette étude, les deux polyosides choisis sont issus de tubercules de plantes abondantes dans la nature.L’amidon est connu pour interagir avec des composés volatils, soit en les piégeant dans la zone amorphe, soit en formant des complexes d'inclusion. Ce phénomène est appelé encapsulation moléculaire. Cependant, les matrices amylacées à forte

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Books on the topic "Compound stability"

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Switzenbaum, Michael S. Defining biosolids stability: A basis for public and regulatory acceptance ; project 94-REM-1. Water Environment Research Foundation, 1997.

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Trissel, Lawrence A. Trissel's stability of compounded formulations. 4th ed. American Pharmacists Association, 2009.

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Trissel's stability of compounded formulations. American Pharmaceutical Association, 1996.

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Trissel, Lawrence A. Trissel's stability of compounded formulations. 5th ed. American Pharmacists Association, 2012.

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Trissel, Lawrence A. Trissel's stability of compounded formulations / Lawrence A. Trissel. 3rd ed. American Pharmacists Association, 2005.

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Trissel, Lawrence A. Trissel's stability of compounded formulations / Lawrence A. Trissel. 3rd ed. American Pharmacists Association, 2004.

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Laatikainen, Markku. Stability of aqueous emulsions of synthetic and extracted wood pitches. Lappeenranta University of Technology, 1992.

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Stable radicals: Fundamentals and applied aspects of odd-electron compounds. Wiley, 2010.

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A, Turchi Patrice E., ed. Complex inorganic solids: Structural, stability, and magnetic properties of alloys. Springer, 2005.

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MacLean, L. A. H. The structure of manganese dioxide-hydrogen insertion compounds and some related stability studies. Middlesex University, Energy Technology Centre, 1993.

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Book chapters on the topic "Compound stability"

1

Kuznezova-Sholpo, I. A. "Compound metrics with fixed minimal ones." In Stability Problems for Stochastic Models. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/bfb0074819.

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Zubkov, A. M. "On compound probabilistic metrics with given minimal metrics." In Stability Problems for Stochastic Models. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/bfb0074832.

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Moroz, Mykola, Fiseha Tesfaye, Pavlo Demchenko, et al. "Thermal Stability and Thermodynamics of the Ag2ZnGeS4 Compound." In Materials Processing Fundamentals 2019. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-05728-2_20.

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Chauhan, A., C. Maldarelli, D. Papageorgiou, and D. Rumschitzki. "The Linear Stability of A Two-Phase Compound Jet." In IUTAM Symposium on Non–Linear Singularities in Deformation and Flow. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-4736-1_24.

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Morand, Kenneth L., and Xueheng Cheng. "Organic Compound Stability in Large, Diverse Pharmaceutical Screening Collections." In Analysis and Purification Methods in Combinatorial Chemistry. John Wiley & Sons, Inc., 2004. http://dx.doi.org/10.1002/0471531979.ch13.

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Kettle, S. F. A. "Stability of coordination compounds." In Physical Inorganic Chemistry. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-662-25191-1_5.

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Streng, William H. "Solution Stability." In Characterization of Compounds in Solution. Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1345-2_8.

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Freeman, A. J. "Structural Stability of Intermetallic Compounds: A Computational Metallurgical Approach." In Alloy Phase Stability. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0915-1_26.

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Muzammil, Saima, Rahat Andleeb, Maria Rasool, Farkhanda Asad, and Asma Ashraf. "Stability Studies of Proteinous Compounds." In Drug Stability and Chemical Kinetics. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6426-0_13.

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Mishima, Yoshinao, and Tomoo Suzuki. "Mechanical Properties and Phase Stability of L12 Ni3Al Ternary Compounds." In Alloy Phase Stability. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0915-1_3.

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Conference papers on the topic "Compound stability"

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Huang, Hong-Bin, Cai-Guang Gao, Zhitao Zhuang, and Xiao-Wei Dong. "Stability of compound nonlinear systems with observer." In Measurement Technology and Intelligent Instruments, edited by Li Zhu. SPIE, 1993. http://dx.doi.org/10.1117/12.156390.

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Kujime, Takaya, Yoshiaki Taniguchi, Daiu Akiyama, Yusuke Kawamura, Yasuhide Ohno, and Masao Nagase. "High stability of the epitaxial graphene film on SiC substrate." In 2019 Compound Semiconductor Week (CSW). IEEE, 2019. http://dx.doi.org/10.1109/iciprm.2019.8819200.

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Kuribara, Kazunori, Taiki Nobeshima, Atsushi Takei, Takehito Kozasa, Sei Uemura, and Manabu Yoshida. "Long-term stability of organic physically unclonable function for IoE security." In 2019 Compound Semiconductor Week (CSW). IEEE, 2019. http://dx.doi.org/10.1109/iciprm.2019.8819220.

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Ho, Chun Yuen, Chao Ping Liu, Yi-Chun Chen, Zhi-Quan Huang, Feng-Chuan Chuang, and Kin Man Yu. "Effects of the Growth Environment on the Phase Stability of Sputter-deposited CdxZn1-xO Alloys." In 2019 Compound Semiconductor Week (CSW). IEEE, 2019. http://dx.doi.org/10.1109/iciprm.2019.8819141.

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Koyama, Masatoshi, Toyokazu Kaneko, Sodai Fujiwara, Toshihiko Maemoto, and Shigehiko Sasa. "The thermal stability of $\varepsilon$-Ga2O3 thin films grown on (111) 3C-SiC template substrates." In 2019 Compound Semiconductor Week (CSW). IEEE, 2019. http://dx.doi.org/10.1109/iciprm.2019.8819218.

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Rao, Anand, Amit Warrier, and Gaurav Raina. "Stability analysis of compound TCP with adaptive virtual queues." In 2013 25th Chinese Control and Decision Conference (CCDC). IEEE, 2013. http://dx.doi.org/10.1109/ccdc.2013.6561291.

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Lin, Qing, Zhihao Cai, and Yingxun Wang. "Dynamics, stability and control characteristics of unmanned compound autogyro." In 2016 IEEE Chinese Guidance, Navigation and Control Conference (CGNCC). IEEE, 2016. http://dx.doi.org/10.1109/cgncc.2016.7828880.

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Grimes, Steven M., T. N. Massey, B. M. Oginni, et al. "Nuclear Level Densities Off of the Stability Line." In COMPOUND-NUCLEAR REACTIONS AND RELATED TOPICS: Proceedings of the 2007 International Workshop on Compound-Nuclear Reactions and Related Topics - CNR∗ 2007. AIP, 2008. http://dx.doi.org/10.1063/1.2920746.

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Machda, Fahmi, Takaya Ogawa, Hideyuki Okumura, and Keiichi N. Ishihara. "Development of Carrier Concentration and Its Effects on the Electrical Stability of Al-doped ZnO Transparent Electrode in Harsh Environment." In 2019 Compound Semiconductor Week (CSW). IEEE, 2019. http://dx.doi.org/10.1109/iciprm.2019.8819365.

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Limero, Thomas, Steve Beck, Patti Cheng, and Vanessa De Vera. "Study of Long-Term Compound Stability in Dual Sorbent Tubes." In International Conference On Environmental Systems. SAE International, 2005. http://dx.doi.org/10.4271/2005-01-3093.

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Reports on the topic "Compound stability"

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Hewitt, Alan D. Concentration Stability of Four Volatile Organic Compounds in Soil Subsamples. Defense Technical Information Center, 1994. http://dx.doi.org/10.21236/ada280124.

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Demchyna, Bohdan, and Yaroslav Shydlovskyi. Recommendations for Designing Wooden Arches on Metal-toothed Plates. Intellectual Archive, 2021. http://dx.doi.org/10.32370/ia_2021_03_18.

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This paper presents the findings of the pilot studies and recommendations for designing of two-hinged wooden arches. The prototype models of wooden arches with the span of 6mand the rise of 1m were designed. The models had a rectangular cross-section of 180x40mm and a T-section of 180x40mm with a plywood plate with the thickness of 6 mm and the width of 500mm. The main objective of the T-section was to ensure the stability of the arch. Each arch was composed of six segments –boards joined by clamping plates. The bowstring truss including two inclined tie bars enables carrying asymmetric loads

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Terzyan, Aram. Post-Soviet State - Building in Kyrgyzstan: Behind and Beyond the Revolutions. Eurasia Institutes, 2021. http://dx.doi.org/10.47669/caps-1-2021.

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This paper explores post-Soviet state-building in Kyrgyzstan, with a focus on the root causes of the three revolutions faced by the country. It suggests that the revolutions have not produced significant results in terms of fundamental economic and political reforms. Rather, Kyrgyzstan has turned into the Central Asian “island of instability”. The situation is compounded by deep- rooted inter-ethnic tensions, the prevalence of traditional informal institutions and weakness of democratic institutions, as well as country’s heavy reliance on international donors. The presidential elections and co

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Chu, F., T. E. Mitchell, S. P. Chen, M. Sob, R. Siegl, and D. P. Pope. Experimental and theoretical studies on the C15 intermetallic compounds MV{sub 2} (M = Zr, Hf and Ta): Elasticity and phase stability. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/10103495.

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Trowbridge, L. D. Thermodynamic stability of complexes of BF{sub 3}, PF{sub 5} and AsF{sub 5} with chlorine fluorides, oxyfluorides, and related compounds. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/269026.

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Gering, Kevin L., Mason K. Harrup, Eric J. Dufek, et al. Section IV.D.3 for DOE 2013 Annual Report: Novel Phosphazene-based Compounds to Enhance Safety and Stability of Cell Chemistries for High Voltage Applications (INL). Office of Scientific and Technical Information (OSTI), 2013. http://dx.doi.org/10.2172/1116750.

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Eveland, Stephanie L. The role of VEC and local atomic environment in structural transitions and stability of complex intermetallic compounds through theoretical and experimental study of γ-brasses. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1593316.

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Wiemers, K. D., H. Babad, R. T. Hallen, L. P. Jackson, and M. E. Lerchen. An Assessment of the Stability and the Potential for In-Situ Synthesis of Regulated Organic Compounds in High Level Radioactive Waste Stored at Hanford, Richland, Washington. Office of Scientific and Technical Information (OSTI), 1999. http://dx.doi.org/10.2172/2535.

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