Relevant bibliographies by topics / Compression Tablet / Dissertations / Theses
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Dissertations / Theses on the topic 'Compression Tablet'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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1

Govan, Otesh Thakorlal. "Time dependent effects in powder compression." Thesis, Cardiff University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314682.

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2

Blundell, L. P. "Characterisation and compaction parameters of directly compressible tablet excipients." Thesis, Cardiff University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356740.

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3

Larhrib, El Hassane. "Characterisation & compaction of polyethylene glycols." Thesis, Liverpool John Moores University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242150.

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4

Yelamanchili, Satish Neau Steven H. "Colon specific delivery using ethylcellulose and chitosan in a compression coated tablet." Diss., UMK access, 2006.

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Thesis (M.S.)--School of Pharmacy. University of Missouri--Kansas City, 2006.<br>"A thesis in pharmaceutical science." Typescript. Advisor: Steven H. Neau. Vita. Title from "catalog record" of the print edition Description based on contents viewed Nov. 12, 2007. Includes bibliographical references (leaves 82-87). Online version of the print edition.
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5

Gabrielsson, Jon. "Multivariate methods in tablet formulation." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-268.

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6

Persson, Ann-Sofie. "Flow and Compression of Granulated Powders : The Accuracy of Discrete Element Simulations and Assessment of Tablet Microstructure." Doctoral thesis, Uppsala universitet, Institutionen för farmaci, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-208808.

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Simulations are powerful and important tools for gaining insight into powder processes. Ultimately, simulations have the potential to replace experiments. Thus, accurate models and insight into the essential factors for descriptions of powder behaviour are required. In this thesis, discrete element method (DEM) simulations of granule flow and compression were evaluated to deduce parameters and potential models essential for the experimental and numerical correspondence. In addition, the evolution in tablet microstructure during compression was studied using mercury porosimetry. Granule flow wa
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7

Mahmoodi, Foad. "Compression Mechanics of Powders and Granular Materials Probed by Force Distributions and a Micromechanically Based Compaction Equation." Doctoral thesis, Uppsala universitet, Institutionen för farmaci, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-171874.

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The internal dynamics of powder systems under compression are as of yet not fully understood, and thus there is a necessity for approaches that can help in further clarifying and enhancing the level of understanding on this subject. To this end, the internal dynamics of powder systems under compression were probed by means of force distributions and a novel compaction equation. The determination of force distributions hinged on the use of carbon paper as a force sensor, where the imprints transferred from it onto white paper where converted through calibration into forces. Through analysis of
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8

Tunón, Åsa. "Preparation of Tablets from Reservoir Pellets with an Emphasis on the Compression Behaviour and Drug Release." Doctoral thesis, Uppsala University, Department of Pharmacy, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3411.

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<p>The preparation of multiple unit tablets was investigated in this thesis with the intention of gaining a deeper understanding of some of the factors that influence the properties of such tablets.</p><p>Initially, three different types of pellets (drug, soft and disintegrant pellets) were combined as a model to investigate the ability of the mixture to form disintegrating tablets. The proportions of the different pellets and the type of disintegrant used were factors that independently influenced the tablet properties. Furthermore, the properties of tablets containing drug pellets barrier-co
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9

Alanezi, Abdulkareem Ali. "Development of an Orally Disintegrating Mini-Tablet (ODMTs) Containing Metoclopramide HCl to Enhance Patient Compliance." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1417861431.

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10

Spaniol, Bárbara. "Comparação do comportamento compressional de granulado contendo produto seco por aspersão de phyllanthus niruri l. entre máquinas de comprimir alternativa e rotativa." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/11062.

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Este trabalho foi realizado com a finalidade de avaliar o comportamento compressional de granulado contendo alta concentração de produto seco por aspersão de Phyllanthus niruri em máquinas de comprimir alternativa (MCA) e rotativa (MCR). A partir do material vegetal de P. niruri foram produzidas a solução extrativa e o produto seco por aspersão (PSA). A formulação dos comprimidos foi composta de granulados do PSA (GPSA) (92 %), adjuvantes granulados (GADJ) (7,92 %) e estearato de magnésio (0,08 %). O GPSA foi produzido por granulação por via seca e o GADJ, composto de celulose microcristalina
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11

Tarlier, Nicolas. "Application de la simulation de compression pour l’étude comportementale et l’analyse des performances de poudres de mannitol DC." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT177.

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Le travail réalisé concerne l’étude de la fonctionnalité et des performances des poudres de mannitol en compression directe en s’appuyant sur la simulation de compression sur presse rotative comme outil d’investigations. Dans le contexte réglementaire actuel, il est important pour les industriels, fournisseurs d’excipients pharmaceutiques, d’approfondir leurs connaissances des matériaux afin de répondre aux critères de qualité des médicaments et aux exigences de l’industrie pharmaceutique. Le mannitol est un excipient très largement utilisé en formulation pharmaceutique et notamment pour la co
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12

Soulairol, Ian. "Etude des phénomènes liés à la conception de mini-comprimés orodispersibles par compression directe." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT115/document.

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La possibilité d’administrer des formes sèches orales est encore de nos jours un enjeu dans certaines spécialités médicales telles que la pédiatrie, la neurologie ou la gériatrie. Les mini-comprimés orodispersibles présentent un intérêt majeur pour répondre à cette problématique.L’objectif de ce travail est d’étudier les différents phénomènes qui régissent la conception de cette forme pharmaceutique par compression directe.Trois axes de recherche ont été fixés pour la réalisation de ce travail : - Premièrement, étudier les paramètres de formulation et de fabrication des mini-comprimés orodispe
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13

Tarlier, Nicolas. "Application de la simulation de compression pour l’étude comportementale et l’analyse des performances de poudres de mannitol DC." Electronic Thesis or Diss., Montpellier, 2016. http://www.theses.fr/2016MONTT177.

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Le travail réalisé concerne l’étude de la fonctionnalité et des performances des poudres de mannitol en compression directe en s’appuyant sur la simulation de compression sur presse rotative comme outil d’investigations. Dans le contexte réglementaire actuel, il est important pour les industriels, fournisseurs d’excipients pharmaceutiques, d’approfondir leurs connaissances des matériaux afin de répondre aux critères de qualité des médicaments et aux exigences de l’industrie pharmaceutique. Le mannitol est un excipient très largement utilisé en formulation pharmaceutique et notamment pour la co
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14

Fichtner, Frauke. "Identification and Variation of some Functionality Related Characteristics of Pharmaceutically Relevant Solid Materials and their Effect on Product Performance." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7462.

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15

Patel, Chaitanya I. "Design and characterization of direct compression excipients." Thesis, University of Bath, 1986. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370466.

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16

Patel, A. N. "The influence of water on the compressional properties of some solids." Thesis, Cardiff University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374737.

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17

Soares, Luiz Alberto Lira. "Obtenção de comprimidos contendo alto teor de produto seco por aspersão de Maytenus ilicifolia Mart. ex. Reissek - Celastraceae : desenvolvimento tecnológico de produtos intermediários e final." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2002. http://hdl.handle.net/10183/147612.

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As folhas de Maytenus ilicifolia são amplamente utilizadas na medicina tradicional brasileira no tratamento de distúrbios gástricos. Após a comprovação de sua eficácia e segurança, a referida droga vegetal tem sido objeto de diversos estudos com a finalidade de estabelecer parâmetros para o controle de qualidade. Neste sentido, foi avaliada a viabilidade do desenvolvimento de um método analítico fundamentado na precipitação de taninos empregando povidona como agente seqüestrante. Os dados revelaram que a remoção de taninos em solução é satisfatória quando empregada a povidona insolúvel. Foi ob
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18

Martinello, Tiago. "Desenvolvimento de comprimidos de paracetamol de 500 mg fabricados por compressão direta utilizando o planejamento estatístico de mistura." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-31082006-160216/.

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As formas orais sólidas são as mais utilizadas pela sua facilidade de administração e transporte, além de proporcionarem maior estabilidade, se comparadas às líquidas ou semi-sólidas. Dentre os sólidos orais, os comprimidos destacam-se por apresentarem processo de fabricação relativamente fácil, com alta produtividade e baixo custo. A compressão direta é o método preferencial para a produção de comprimidos pois economiza tempo e energia, é ambientalmente menos agressiva e reduz investimentos em equipamentos e na estrutura da área de produção, por requerer menor número de etapas no processament
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19

Rujivipat, Soravoot [Verfasser]. "Novel formulation and processing aspects for compression coated tablets and for the compression of polymer-coated multiparticulates / Soravoot Rujivipat." Berlin : Freie Universität Berlin, 2010. http://d-nb.info/102478455X/34.

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20

Ediev, Dalkhat. "Mortality compression in period life tables hides decompression in birth cohorts in low-mortality countries." Sapienza University of Rome, 2013. http://dx.doi.org/10.4402/genus-451.

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The rapid increase in human longevity has raised important questions about what implications this development may have for the variability of age at death. Earlier studies have reported evidence of a historical trend towards mortality compression. However, the period life table model, commonly used to address mortality compression, produces a compressed picture of mortality as a built-in feature of the model. To overcome this limitation, we base our study on an examination of the durations of exposure, in years of age, of birth cohorts and period life tables to selected short ranges of the dea
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21

Thomas, William Iwan. "The effects of material characteristics on the compression and properties of dry coated tablets." Thesis, University of Sunderland, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264762.

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22

Sanderson, I. M. "The effect of formulation and maufacturing processes on the characterisitics of direct compression tablets." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372670.

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23

Kieser, Leith Faye. "Formulation and assessment of monolithic beta blocker sustained release tablets prepared by direct compression." Thesis, Rhodes University, 2002. http://hdl.handle.net/10962/d1003242.

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Beta blockers are commonly prescribed for the chronic treatment of hypertension, one of the most prolific disease states worldwide. The beta blockers selected for this study include acebutolol hydrochloride, labetalol hydrochloride, metoprolol tartrate oxprenolol hydrochloride and propranolol hydrochloride. All of these compounds have a short elimination half-life, necessitating multiple dose per day regimens and therefore the development of sustained release dosage forms incorporating these agents was considered beneficial in terms of extending the dosing interval, with the aim of improving p
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24

Eissa, Salah. "Condition monitoring of pharmaceutical powder compression during tabletting using acoustic emission." Thesis, Brunel University, 2003. http://bura.brunel.ac.uk/handle/2438/5244.

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This research project aimed to develop a condition monitoring system for the final production quality of pharmaceutical tablets and detection capping and lamination during powder compression process using the acoustic emission (AE) method. Pharmaceutical tablet manufacturers obliged by regulatory bodies to test the tablet's physical properties such as hardness, dissolution and disintegration before the tablets are released to the market. Most of the existing methods and techniques for testing and monitoring these tablet's properties are performed at the tablet post-compression stage. Furthermo
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25

Bürki, Kathrin Eva [Verfasser]. "Preparation of taste masked orally disintegrating tablets by compression of coated pellets / Kathrin E. Bürki." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1111558825/34.

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26

Nordström, Josefina. "Compression analysis as a tool for technical characterization and classification of pharmaceutical powders." Doctoral thesis, Uppsala University, Department of Pharmacy, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9214.

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<p>There are today strong incentives for an increased understanding of material properties and manufacturing processes to facilitate the development of new technologies in the pharmaceutical industry. The purpose of this thesis was to suggest methods requiring a low sample amount for characterization of technical properties of powders.</p><p>Compression analysis was used to evaluate the formulation relevance of some compression equations. Using the mechanics of single granules to estimate powder functionality was part of this work. It was concluded that the formability of granular solids and t
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27

Sabeh, Darwiche. "Adapting the Green and Ampt model to account for air compression and counterflow." [Tampa, Fla.] : University of South Florida, 2004. http://purl.fcla.edu/fcla/etd/SFE0000493.

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28

Gharbi, Nebras. "On compressing and parallelizing constraint satisfaction problems." Thesis, Artois, 2015. http://www.theses.fr/2015ARTO0406/document.

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La programmation par contraintes est un cadre puissant utilisé pour modéliser et résoudre des problèmes combinatoires, employant des techniques d'intelligence artificielle, de la recherche opérationnelle, de théorie des graphes,..., etc. L'idée de base de la programmation par contraintes est que l'utilisateur exprime ses contraintes et qu'un solveur de contraintes cherche une ou plusieurs solutions.Les problèmes de satisfaction de contraintes (CSP), sont au cœur de la programmation par contraintes. Ce sont des problèmes de décision où nous recherchons des états ou des objets satisfaisant un ce
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29

Chillas, Stephanie M. "The Formulation and Evaluation of Orally Disintegrating Tablets: Diphenhydramine HCl." University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1371774622.

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30

Joaquim, Mauricio Martinelli. "Flexão e flexo-compressão em elementos de alvenaria estrutural." Universidade de São Paulo, 1999. http://www.teses.usp.br/teses/disponiveis/18/18134/tde-19042018-085707/.

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Este trabalho trata da verificação e dimensionamento de peças de alvenaria estrutural submetidas à flexão. Inicialmente são apresentados os conceitos básicos do método das tensões admissíveis e são desenvolvidos procedimentos para a análise do problema da flexão simples e composta reta. Em seguida discute-se o problema da flexão composta oblíqua, com ênfase à modelagem computacional necessária ao desenvolvimento de aplicativos para a análise de seções genéricas. São apresentados na seqüência dois programas computacionais, implementados a partir dos algoritmos e procedimentos desenvolvidos nos
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31

Nofrerias, Roig Isaac. "Aplicació de la simulació de compressió a l’estudi del comportament i optimització de comprimits elaborats per compressió directa utilitzant el sistema expert SeDeM." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/668064.

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El comprimit és la forma farmacèutica més freqüent al mercat. El procés tecnològic d’elaboració de comprimits d’elecció és la compressió directa perquè permet un estalvi en el nombre d’etapes. Tanmateix, aquest procés requereix que les pólvores presentin unes característiques adequades per la compressió per se. La necessitat de dissenyar ràpidament una fórmula farmacèutica que compleixi els estàndards de compressió i l’escalat a producció industrial, ha portat a la creació de sistemes experts i simuladors de compressió. En la present tesis, s’optimitza el sistema expert de diagrama SeDeM i es
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32

Lukyanets, Yuliya. "The Green and Ampt Infiltration Model Accounting for Air Compression and Air Counterflow in the Shallow Water Table Environment: Laboratory Experiments." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3471.

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Water infiltration into the unsaturated zone especially in a shallow water table environment is affected by air compression ahead of the wetting front and air counterflow. Neglecting air compression in infiltration modeling can overestimate infiltration and infiltration rates, whereas not accounting for air counterflow can underestimate infiltration and infiltration rates due to unrealistic buildup of air pressure resistance ahead of the wetting front. A method, derived on the basis of the Green and Ampt (1911) infiltration model, is introduced to simulate air compression and air counterflow d
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33

Bruna, Arcangelo Ranieri. "Applied Image Processing Algorithms for Forensic Applications." Doctoral thesis, Università di Catania, 2013. http://hdl.handle.net/10761/1316.

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The research activities described in this thesis have been mainly focused on the analysis and development of techniques able to detect image forgeries. The first part of the thesis has been devoted on detecting tampering by using compression artifacts analysis. Driven by an application aiming to retrieve the original camera model used to shoot the image, two research topics have been targeted: the cropping detection, i.e. the operation that allows obtaining a subpart of the image, and the double quantization detection, i.e. the fact that an image, previously compressed, is opened, modified and
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34

Mazzon, Nicola. "Infuence of Grout Injection on the Dynamic Behaviour of Stone Masonry Buildings." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3422728.

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The Italian and European regions are characterized by a wide diffusion of structures in the minor historical centres. The decay condition, in which part these buildings are, makes often necessary structural interventions to preserve they integrity. This way, during last decades several new intervention methodologies were developed, employing both innovative and traditional materials, with the aim to avoid further damages, particularly those induced by seismic events. However, these new materials and techniques are often commercialized and employed without any preliminary exhaustive study to ver
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35

Kratz, Cristiane de Pellegrini. "Obtenção de comprimidos contendo grânulos deformantes e grânulos revestidos gastro-resistentes." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2002. http://hdl.handle.net/10183/147657.

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Sistemas monolíticos particulados contendo os constituintes ativos veiculados na forma de grânulos revestidos - pellets - têm recebido crescente atenção nos últimos anos, em função da otimização na biodisponibilidade e segurança na liberação do fármaco. A utilização destas unidades, como componentes de comprimidos traz, como principal vantagem, a divisibilidade da forma sem a perda do perfil biofarmacêutico desejado para o fármaco. Para sua produção, é indispensável a manutenção da integridade do revestimento daquelas unidades. Uma estratégia para o alcance deste objetivo envolve a utilização
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Agossou, Yémalin. "Étude de la mise en oeuvre du rotin et du rônier comme armature des nervures et armatures de paillasse de la table de compression en béton de latérite." Electronic Thesis or Diss., Université de Lorraine, 2021. https://docnum.univ-lorraine.fr/public/DDOC_T_2021_0350_AGOSSOU.pdf.

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Chacun s’accorde aujourd’hui sur l’impact de la production des matériaux industrielles sur le climat de la planète. Le secteur de la construction est l’un des principaux responsables de cette situation car c’est le premier consommateur d’énergie et le deuxième émetteur de CO2 dans le monde. L’épuisement de certains gisements de matériaux est aussi l’un des problèmes que connait l’humanité. Il importe par conséquent de réaliser des bâtiments éco-respectueux, qui consomment peu d’énergie et émettent moins de gaz à effet de serre sur l’ensemble de leur cycle de vie. La présente étude s’intègre da
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Gallé, Matthias. "Searching for Compact Hierarchical Structures in DNA by means of the Smallest Grammar Problem." Phd thesis, Université Rennes 1, 2011. http://tel.archives-ouvertes.fr/tel-00595494.

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Motivé par la découverte automatique de la structure hiérarchique de séquences d'ADN, nous nous intéressons au probléme classique de la recherche de la plus petite grammaire algébrique générant exactement une séquence donnée. Ce probléme NP-dur a été largement étudié pour des applications comme la compression de données, la découverte de structure et la théorie algorithmique de l'information. Nous proposons de décomposer ce probléme en deux problémes d'optimisation complémentaires. Le premier consiste á choisir les chaînes de la séquence qui seront les constituants de la grammaire finale alors
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Gallé, Matthias. "Searching for compact hierarchical structures in DNA by means of the smallest grammar problem." Phd thesis, Rennes 1, 2011. http://www.theses.fr/2011REN1S033.

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Motivated by the goal of discovering hierarchical structures inside DNA sequences, we address the Smallest Grammar Problem, the problem of finding a smallest context-free grammar that generates exactly one sequence. This NP-Hard problem has been widely studied for applications like Data Compression, Structure Discovery and Algorithmic Information Theory. We give a new formalisation of this problem in form of a complete and correct search space. This search space is based on the decomposition of the problem into two complementary optimisation problems. The first one consists in choosing which s
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Campolina, Alessandro Gonçalves. "O efeito da eliminação de doenças crônicas na população idosa: a compressão e a expansão da morbidade." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/6/6132/tde-18042012-084358/.

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Introdução: No contexto do envelhecimento populacional, uma questão fundamental é avaliar se as estratégias de prevenção de doenças crônicas poderiam contribuir para o aumento dos anos vividos em boas condições de saúde, pela população idosa. Objetivo: Avaliar se a eliminação de determinadas doenças crônicas é capaz de levar à compressão da morbidade em indivíduos idosos. Métodos: Estudo transversal analítico, de base populacional, utilizando dados oficiais secundários para o Município de São Paulo, em 2000, e dados obtidos a partir do estudo SABE. O método de Sullivan foi utilizado para o cál
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40

Kaščák, Andrej. "Komprese záznamů o IP tocích." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2011. http://www.nusl.cz/ntk/nusl-235520.

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My Master's thesis deals with the problems of flow compression in network devices. Its outcome should alleviate memory consumption of the flows and simplify the processing of network traffic. As an introduction I provide a description of protocols serving for data storage and manipulation, followed by discussion about possibilities of compression methods that are employed nowadays. In the following part there is an in-depth analysis of source data that shows the structure and composition of the data and brings up useful observations, which are later used in the testing  of existing compressio
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Vorel, Pavel. "Vlastnosti betonů s přídavkem plazmatem upravených polypropylenových vláken." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2013. http://www.nusl.cz/ntk/nusl-225879.

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Master‘s thesis focuses on concrete combined with polypropylen fibres produced commercially, fibres without surface modifications and fibres modificated by plasma. Most important topic of the thesis is experimental verification of influence of plasma modificated fibres on attributes of fresh concrete and physical-mechanical attributes of solidified concrete. Based on the results of the tests perfomed on examin units compares results and anylyses applicability of different fibre surface modifications.
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42

Altaf, Syed Azhar. "Tablet machine instrumentation to study tablet compaction and compression of polymer-coated beads into tablets." Thesis, 1995. http://hdl.handle.net/1957/34666.

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43

CHEN, SHU-LING, and 陳淑玲. "1. Direct compression studies on metronidazole tablet formulation 2.Studies on the improvement of three layer tablet formulation." Thesis, 1992. http://ndltd.ncl.edu.tw/handle/98184809930606479223.

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Rowe, Raymond C., A. P. Plumb, Peter York, and M. Brown. "Optimisation of the predictive ability of artificial neural network (ANN) models: A comparison of three ANN programs and four classes of training algorithm." 2005. http://hdl.handle.net/10454/3011.

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No<br>The purpose of this study was to determine whether artificial neural network (ANN) programs implementing different backpropagation algorithms and default settings are capable of generating equivalent highly predictive models. Three ANN packages were used: INForm, CAD/Chem and MATLAB. Twenty variants of gradient descent, conjugate gradient, quasi-Newton and Bayesian regularisation algorithms were used to train networks containing a single hidden layer of 3¿12 nodes. All INForm and CAD/Chem models trained satisfactorily for tensile strength, disintegration time and percentage dissolutio
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Bani, Jaber Ahmad Kh. "Formulation and in vitro-in vivo evaluation of a new compression-coated tablet of amoxicillin/clavulanate and formulation potential of the antimicrobial peptide nisin." Thesis, 1998. http://hdl.handle.net/1957/33186.

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This thesis is compromised of two distinct formulation sections, which are described below: New compression-coated tablet formulations were developed for amoxicillin/clavulanate. Amoxicillin in an outer coat was separated from clavulanic acid in a core tablet by inactive ingredients in a middle coat. A chewable compression-coated tablet formulation with 50% stearic acid in the middle coat showed high clavulanic acid stability in comparison to the marketed traditional tablet formulation. Stearic acid acted as a hydrophobic barrier that prevents passage of moisture through the outer coats into t
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Penedo, Maria Simões. "Novel shape in scored orodispersible tablets applying Design of Experiments." Master's thesis, 2017. http://hdl.handle.net/10451/36072.

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Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2017<br>Drug Delivery Systems (DDS) are a strategic tool that has become increasingly sophisticated over the years. Their main contributions involve expanding the life cycle of pharmaceutical products, by improving the administration process according to the patient’s needs. Since the drug delivery through oral route still represents the most common and preferred way of drug administration, our work of study relies on the development of orodispersible tablets (ODTs). This dosage form pr
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Vávrová, Kateřina. "Hodnocení disoluce tablet obsahujících theofylin a směsi dvou typů hydrogenfosforečnanu vápenatého a mikrokrystalické celulosy." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-367733.

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Charles University in Prague, Faculty of Pharmacy in Hradci Králové Department of Pharmaceutical technology Consultant: PharmDr. Pavel Ondrejček, Ph.D. Student: Kateřina Vávrová Title of Thesis: Dissolution testing of tablets containing theophylline and mixtures of two types of calcium hydrogen phosphates and microcrystalline cellulose The aim of this thesis was the dissolution testing of tablets containing theophylline, the mixture of two dicalcium phosphate types and microcrystalline cellulose. The influence of tablet composition on the dissolution profiles was evaluated. The tablets were pr
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Brtnová, Soňa. "Hodnocení doby rozpadu tablet obsahujících theofylin." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-331742.

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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical Technology Thesis supervisor: Doc. PharmDr. Zdeňka Šklubalová, Ph.D. Consultant: Mgr. Pavel Ondrejček Student: Soňa Brtnová Title of Thesis: Evaluation of disintegration time of tablets containing theophylline The influence of used fillers on energetic profile of compression, especially influence on disintegration time of tablets with theophylline as a model drug, was studied in this thesis. Four tablet fillers were studied - microcrystalline cellulose Comprecel 102, lactose SpheroLac 100, calcium
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Janoutová, Hana. "Hodnocení radiální pevnosti tablet obsahujících theofylin." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-331743.

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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Consultant: Doc. PharmDr. Zdeňka Šklubalová, Ph.D. Student: Hana Janoutová Title of Thesis: Evaluation of tensile strength of tablets containing theophylline The aim of this thesis was to determine tensile strength of tablets containing theophylline. Tensile strength was studied as a function of the composition of mixtures of the used fillers and especially on their ratio. In the theoretical part, the used materials - lactose SpheroLac 100, microcrystalline cellulose Comprecel 102, dibas
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Matyášová, Andrea. "Hodnocení lisovatelnosti tablet s theofylinem pomoci lisovací rovnice." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-331958.

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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department: Department of Pharmaceutical Technology Consultant: Doc. PharmDr. Zdeňka Šklubalová, Ph.D. Student: Andrea Matyášová Title of Thesis: Evaluation of compressibility of tableting mixtures containing theophylline using a compaction equation This thesis is aimed at the evaluation and comparison of excipients used in production of tablets. The compaction process of these excipients was evaluated using the parameters of the compaction equation. The mixtures of four fillers in various ratios were evaluated. These mixtures
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