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1

Rodríguez, Santiago, José L. Pedraza, Antonio García, Francisco Rosales, and Rafael Méndez. "Computer-Assisted Assembly Language Programming Laboratory." International Journal of Electrical Engineering & Education 44, no. 3 (July 2007): 216–29. http://dx.doi.org/10.7227/ijeee.44.3.2.

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This paper presents a new approach for managing laboratory work mini-projects that is used in the Computer Architecture Department of the Technical University of Madrid (UPM). The approach is based on a chain of tools (a Delivery Agent; an Automatic Project Evaluator; and a Plagiarism Detection Assistant) that a small number of teachers can use to efficiently manage a course with a large number of students (400 each year). Students use this tool chain to complete the Assembly Language Programming laboratory assignments using an MC88110 simulator built in our department. Jointly, these tools have demonstrated over the last decade what important benefits can be gained from the exploitation of a global laboratory work management system. Some of the benefits may have a continuation in an area of growing importance that we have not yet explored, such as distance learning environments for technical subjects.
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Goos, Jan, Pieter Lietaert, and Robbe Cools. "Computer assisted ergonomic assembly cell design." Procedia CIRP 97 (2021): 87–91. http://dx.doi.org/10.1016/j.procir.2020.05.208.

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3

Luecht, Richard M. "Computer-Assisted Test Assembly Using Optimization Heuristics." Applied Psychological Measurement 22, no. 3 (September 1998): 224–36. http://dx.doi.org/10.1177/01466216980223003.

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4

Sarraipa, F. M., D. V. Macedo, and E. Galembeck. "PATHWAY ASSEMBLY ASSISTED BY COMPUTER: TEACHING ANAEROBIC GLYCOLYSIS." Revista de Ensino de Bioquímica 6, no. 1 (May 20, 2008): 15. http://dx.doi.org/10.16923/reb.v6i1.87.

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Lye, Sun‐Woh, and Nan‐Shing Ong. "Computer Assisted Geometric Analysis of Components for Automatic Assembly." Integrated Manufacturing Systems 4, no. 2 (February 1993): 4–14. http://dx.doi.org/10.1108/09576069310037446.

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6

Rahnejat, H. "Simulating for ‘Resource Optimization’ in Robot-Assisted Automatic Assembly." Proceedings of the Institution of Mechanical Engineers, Part B: Management and engineering manufacture 200, no. 3 (August 1986): 181–86. http://dx.doi.org/10.1243/pime_proc_1986_200_069_02.

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In most manufacturing systems emphasis is now given to resource flexibility in operation. The aim is to respond swiftly to changes in product mix and/or market demands. Discrete event computer simulation is seen as a tool in defining a suitable system configuration at the preliminary design stage. Furthermore, simulation in dynamic form can represent the interactions between the system components and provide a detailed prediction of its performance. Although many existing computer simulation packages have reached a good level of general purpose modelling, by and large they lack the required versatility to deal with some specific features of manufacturing systems. One such important area is the robot-assisted automatic assembly where minimization of non-productive activities in the product assembly cycle is of vital interest. This paper introduces a flexible modelling technique which identifies the resource utilization and optimization levels during the individual processes of a product assembly cycle. Within the working constraints of an assembly system, an ‘optimal’ robot sequential cycle is obtained by implementing this modelling technique in GPSL (general purpose simulation language).
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7

Xu, Meng, Travis A. Jarrell, Yi Wang, Steven J. Cook, David H. Hall, and Scott W. Emmons. "Computer Assisted Assembly of Connectomes from Electron Micrographs: Application to Caenorhabditis elegans." PLoS ONE 8, no. 1 (January 16, 2013): e54050. http://dx.doi.org/10.1371/journal.pone.0054050.

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8

Bußmann, J. "Rechnerunterstutzte Montagesteuerung im Werkzeugmaschinenbau / Computer-assisted assembly control in machine-tool engineering." Zeitschrift für wirtschaftlichen Fabrikbetrieb 89, no. 4 (April 1, 1994): 188–90. http://dx.doi.org/10.1515/zwf-1994-890425.

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9

Jin, Zhangjun, Cijun Yu, Jiangxiong Li, and Yinglin Ke. "A robot assisted assembly system for small components in aircraft assembly." Industrial Robot: An International Journal 41, no. 5 (August 12, 2014): 413–20. http://dx.doi.org/10.1108/ir-03-2014-0310.

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Purpose – The purpose of this paper is to propose a robot-assisted assembly system (RAAS) for the installation of a variety of small components in the aircraft assembly system. The RAAS is designed to improve the assembly accuracy and increase the productive efficiency. Design/methodology/approach – The RAAS is a closed-loop feedback system, which is integrated with a laser tracking system and an industrial robot system. The laser tracking system is used to evaluate the deviations of the position and orientation of the small component and the industrial robot system is used to locate and re-align the small component according to the deviations. Findings – The RAAS has exhibited considerable accuracy improvement and acceptable assembly efficiency in aircraft assembly project. With the RAAS, the maximum position deviation of the component is reduced to 0.069 mm and the maximum orientation deviation is reduced to 0.013°. Social implications – The RAAS is applied successfully in one of the aircraft final assembly projects in southwest China. Originality/value – By integrating the laser tracking system, the RAAS is constructed as a closed-loop feedback system of both the position and orientation of the component. With the RAAS, the installation a variety of small components can be dealt with by a single industrial robot.
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Berto Nadeak and Sony Bahagia Sinaga. "Perancangan Perangkat Lunak Pembelajaran Mikroprosesor Dengan Menggunakan Metode Computer Assisted Instruction." JUKI : Jurnal Komputer dan Informatika 2, no. 2 (May 7, 2021): 85–88. http://dx.doi.org/10.53842/juki.v2i2.31.

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The microprocessor that became the machine for the IBM PC / XT microcomputers and their compatible. This processor is often referred to as simply "8088" or "8086". Although the hardware of the 8088 is slightly different from the 8086, they can be viewed as the same from a programming perspective. The Intel 8088/8086 is a 16 bit processor, meaning that the data path and registers are 16 bits in size. The addressing mode is divided into several types, among others, register addressing, immediate addressing, direct addressing and indirect addressing. In addition, in learning Assembly language, we must memorize all registers and understand their use. Computer Aided Instruction (CAI) is a variety of information in the way of learning. Computers as a medium will help students find new things that are more interesting than conventional teacher-centered ways. Although it is known that the ways of learning and teaching, as well as the acquisition of learning information for each individual are different.
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Schubert, M., and K. Feiten. "Rechnerunterstützte Montageplanung optimiert die Wertschöpfung / Computer-assisted assembly planning optimizes the added value." Zeitschrift für wirtschaftlichen Fabrikbetrieb 89, no. 4 (April 1, 1994): 194–96. http://dx.doi.org/10.1515/zwf-1994-890427.

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12

Schwartz, David N., Ulysses S. Wu, Rosie D. Lyles, Yingxu Xiang, Piotr Kieszkowski, Bala Hota, and Robert A. Weinstein. "Lost in Translation? Reliability of Assessing Inpatient Antimicrobial Appropriateness With Use of Computerized Case Vignettes." Infection Control & Hospital Epidemiology 30, no. 2 (February 2009): 163–71. http://dx.doi.org/10.1086/593970.

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Objective.To describe and measure reliability of a computer-assisted method of case vignette assembly and expert review to assess the appropriateness of antimicrobial therapy for hospitalized adults.Design.Feasibility and reliability analysis of computer-assisted tool used to compare the effects of antimicrobial stewardship interventions.Setting.Public teaching hospital.Patients.Randomly selected adult antimicrobial recipients admitted to inpatient medicine services.Methods.Clinical data abstracted from 504 paper medical records were merged with computerized laboratory and pharmacy data to assemble case vignettes that underwent expert review for appropriateness. We performed 3 validations, as follows: data for 35 vignettes abstracted independently by 2 research assistants were assessed for interrater agreement, expert review of 24 vignettes was compared with review of the corresponding paper medical records, and interrater reliability of antimicrobial appropriateness assessments by 2 experts was determined for 70 case vignettes.Results.Vignette assembly and expert review each required 10–12 minutes per case. Potentially important discrepancies occurred in 0%–32% of clinical findings abstracted independently by 2 research assistants. Expert review of 24 vignettes and the corresponding full paper medical records yielded fair agreement (kappa, 0.30). The 2 experts identified inappropriate initial antimicrobial therapy in 67% and 61% of case vignettes reviewed independently; interrater agreement was improved after sequential case discussion and stringent application of appropriateness criteria (kappa, 0.72).Conclusions.Our case vignette assembly and expert review method is efficient, but improvements in both technical and human performance are needed to be able to yield valid estimates of the prevalence of inappropriate antimicrobial use. Assessments of antimicrobial appropriateness require validation.
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Strasser, Stefan, Albert Zink, Wolfgang M. Heckl, and Stefan Thalhammer. "Controlled Self-Assembly of Collagen Fibrils by an Automated Dialysis System." Journal of Biomechanical Engineering 128, no. 5 (March 12, 2006): 792–96. http://dx.doi.org/10.1115/1.2264392.

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In vitro self-assembled collagen fibrils form a variety of different structures during dialysis. The self-assembly is dependent on several parameters, such as concentrations of collagen and α1-acid glycoprotein, temperature, dialysis time, and the acid concentration. For a detailed understanding of the assembly pathway and structural features like banding pattern or mechanical properties it is necessary to study single collagen fibrils. In this work we present a fully automated system to control the permeation of molecules through a membrane like a dialysis tubing. This allows us to ramp arbitrary diffusion rate profiles during the self-assembly process of macromolecules, such as collagen. The system combines a molecular sieving method with a computer assisted control system for measuring process variables. With the regulation of the diffusion rate it is possible to control and manipulate the collagen self-assembly process during the whole process time. Its performance is demonstrated by the preparation of various collagen type I fibrils and native collagen type II fibrils. The combination with the atomic force microscope (AFM) allows a high resolution characterization of the self-assembled fibrils. In principle, the represented system can be also applied for the production of other biomolecules, where a dialysis enhanced self-assembly process is used.
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14

Knight, Terry, and Lawrence Sass. "Looks count: Computing and constructing visually expressive mass customized housing." Artificial Intelligence for Engineering Design, Analysis and Manufacturing 24, no. 3 (March 15, 2010): 425–45. http://dx.doi.org/10.1017/s0890060409990126.

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AbstractThis paper introduces new research that seeks to develop low-cost, high quality, mass customizable building assembly systems that provide visually rich design variations for housing or other small structures. The building systems are intended to be tailored for particular cultures and communities by incorporating vernacular decorative design into the assembly design. Two complementary research areas are brought together in this work: shape grammars and digital fabrication. The visual, aesthetic aspects of the research are explored through shape grammars. The physical design and manufacturing aspects are explored through advanced digital design and fabrication technologies, and in particular, build on recent work on monomaterial assemblies with interlocking components that can be fabricated with computer numerical control machines and assembled easily by hand. The long-term objective of this research is the development of formal, visual–physical grammars with rules that generate complete computer-assisted design/computer-assisted manufacturing data for fabrication of full-scale components for assembly design variations. This paper reports on the first phase of this research: pilot studies for prototype assembly systems that incorporate vernacular languages from different parts of the world. The results of these studies are very promising, and demonstrate a spectrum of strategies for embedding visual properties in structural systems. Important next steps in this research are outlined. If successful, this work will lead to new solutions for low-cost, easily manufactured housing, which is especially critical in developing countries and for postdisaster environments. These new housing solutions will not only provide shelter but also support important cultural values through the integration of familiar visual design features. Beyond the specific context of housing and building assemblies, the research has the potential to impact the design and manufacture of designed artifacts on many scales and in many domains, especially in domains where visual aesthetics need to be considered jointly with physical, structural, or material requirements, and where design customization and variation is important.
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15

Rey, Carine, Philippe Veber, Bastien Boussau, and Marie Sémon. "CAARS: comparative assembly and annotation of RNA-Seq data." Bioinformatics 35, no. 13 (November 19, 2018): 2199–207. http://dx.doi.org/10.1093/bioinformatics/bty903.

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Abstract Motivation RNA sequencing (RNA-Seq) is a widely used approach to obtain transcript sequences in non-model organisms, notably for performing comparative analyses. However, current bioinformatic pipelines do not take full advantage of pre-existing reference data in related species for improving RNA-Seq assembly, annotation and gene family reconstruction. Results We built an automated pipeline named CAARS to combine novel data from RNA-Seq experiments with existing multi-species gene family alignments. RNA-Seq reads are assembled into transcripts by both de novo and assisted assemblies. Then, CAARS incorporates transcripts into gene families, builds gene alignments and trees and uses phylogenetic information to classify the genes as orthologs and paralogs of existing genes. We used CAARS to assemble and annotate RNA-Seq data in rodents and fishes using distantly related genomes as reference, a difficult case for this kind of analysis. We showed CAARS assemblies are more complete and accurate than those assembled by a standard pipeline consisting of de novo assembly coupled with annotation by sequence similarity on a guide species. In addition to annotated transcripts, CAARS provides gene family alignments and trees, annotated with orthology relationships, directly usable for downstream comparative analyses. Availability and implementation CAARS is implemented in Python and Ocaml and is freely available at https://github.com/carinerey/caars. Supplementary information Supplementary data are available at Bioinformatics online.
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16

Kochs, A. "Computer-assisted assembly and correction simulation for complex axis deviations using the Ilizarov fixator." Archives of Orthopaedic and Trauma Surgery 114, no. 5 (August 1995): 287–91. http://dx.doi.org/10.1007/bf00452089.

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17

Maropoulos, P. G., J. E. Muelaner, M. D. Summers, and O. C. Martin. "A new paradigm in large-scale assembly—research priorities in measurement assisted assembly." International Journal of Advanced Manufacturing Technology 70, no. 1-4 (September 21, 2013): 621–33. http://dx.doi.org/10.1007/s00170-013-5283-4.

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18

Pitchandi, Nagarajan, and Saravana Perumaal Subramanian. "GA‐based camera calibration for vision‐assisted robotic assembly system." IET Computer Vision 11, no. 1 (September 22, 2016): 50–59. http://dx.doi.org/10.1049/iet-cvi.2016.0004.

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19

Wang, Dung-An, and Ben Liao. "Shaking assisted self-assembly of rectangular-shaped parts." Journal of Materials Processing Technology 210, no. 2 (January 2010): 343–50. http://dx.doi.org/10.1016/j.jmatprotec.2009.09.021.

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20

Kanemura, Shingo, Motonori Matsusaki, Kenji Inaba, and Masaki Okumura. "PDI Family Members as Guides for Client Folding and Assembly." International Journal of Molecular Sciences 21, no. 24 (December 8, 2020): 9351. http://dx.doi.org/10.3390/ijms21249351.

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Complicated and sophisticated protein homeostasis (proteostasis) networks in the endoplasmic reticulum (ER), comprising disulfide catalysts, molecular chaperones, and their regulators, help to maintain cell viability. Newly synthesized proteins inserted into the ER need to fold and assemble into unique native structures to fulfill their physiological functions, and this is assisted by protein disulfide isomerase (PDI) family. Herein, we focus on recent advances in understanding the detailed mechanisms of PDI family members as guides for client folding and assembly to ensure the efficient production of secretory proteins.
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21

Brusick, David. "A computer-assisted procedure for the assembly and analysis of short-term genotoxicity test data." Toxicology Letters 49, no. 2-3 (December 1989): 123–38. http://dx.doi.org/10.1016/0378-4274(89)90028-3.

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22

Meereis, CTW, GBF de Souza, LGB Albino, FA Ogliari, E. Piva, and GS Lima. "Digital Smile Design for Computer-assisted Esthetic Rehabilitation: Two-year Follow-up." Operative Dentistry 41, no. 1 (January 1, 2016): E13—E22. http://dx.doi.org/10.2341/14-350-s.

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SUMMARY Objective: The esthetics of the smile are related to the color, shape, texture, dental alignment, gingival contour, and the relationship of these with the face. Purpose: To present a two-year follow-up for an esthetic rehabilitation clinical case in which the method of digital smile design (DSD) was used to assist and improve diagnosis, communication, and predictability of treatment through an esthetic analysis of the assembly: face, smile, periodontal tissue, and teeth. Clinical Procedure: The smile's esthetics were improved through gingival recontouring, dental home bleaching, and a restorative procedure with thin porcelain laminate veneers using lithium disilicate glass-ceramic (e.max Ceram, Ivoclar-Vivadent) laminates on teeth 4 through 13. Discussion: The proposed technique had an acceptable clinical performance at the end of a two-year follow-up. Significance: DSD can be used to increase professional/patient communication and to provide greater predictability for the smile's esthetic rehabilitation.
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Sulong, Abu Bakar, Muhammad Ilman Hakimi Chua Abdullah, Mohd Fazuri Abdullah, San Wei Koon, Nor Hamdan Nor Yahya, and Rizauddin Ramli. "Design Approach for Jig in Computer Assisted Total Knee Replacement Surgery." Key Engineering Materials 447-448 (September 2010): 341–45. http://dx.doi.org/10.4028/www.scientific.net/kem.447-448.341.

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During performing Computer assisted Total Knee surgery, surgeons have difficulties in orientation of cutting block before sawing procedure. The objectives of this study are develop design approach and fabrication of prototype, which able to eliminate stated difficulties. Thus, improve performance and cycle time of total knee surgery. Benchmarking with commercial product had been conducted, two designs of jig system were proposed. Selection of design was conducted using Pugh method. Two designs were compared based on specific requirements, in order to get the most acceptable design. Pugh method analysis shown that the second design give more advantages in handling, easy to operate, least cost in manufacture, and reduction of time in doing the total knee replacement than the first design. Prototype jig assembly consist of arm, base and cutting block were fabricated by rapid protyping for feasibility analysis. Then, simulation of fabrication by machining process was conducted through Mastercam Mill V8. All component were able to fabricated through machining. A prototype of jig system was fabricated using stainless steel typed SS316L, and evaluation of cutting procedure with saw bone confirmed that the second design is fulfill the objectives of this study.
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Kolmogorov, M., B. Raney, B. Paten, and S. Pham. "Ragout--a reference-assisted assembly tool for bacterial genomes." Bioinformatics 30, no. 12 (June 15, 2014): i302—i309. http://dx.doi.org/10.1093/bioinformatics/btu280.

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Nicolescu, Florin Adrian, Georgia Cezara Avram, Andrei Mario Ivan, and Adrian Theodor Mantea. "Brushless Servomotor’s Thermal Behavior Computer Assisted Evaluation for a Linear Motion NC Axis Experimental Stand." Applied Mechanics and Materials 762 (May 2015): 21–26. http://dx.doi.org/10.4028/www.scientific.net/amm.762.21.

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The paper presents works carried out by the authors in the field of NC axes’ structural and functional optimization. This paper includes the results obtained by using a MathCAD application (developed in the doctoral thesis of the second author) for the servomotor's thermal behavior computer assisted evaluation. The analyzed servomotor is included in the driving system of a linear motion NC axis experimental testing stand, (existing in MMS department from EMTS Faculty). The NC axis of the experimental stand integrates a FAGOR brushless servomotor, a 1:1 ratio belt drive intermediary transmission, a ball screw - bearings assembly (lead screw - ball nut - bearings) and a driven element guided through a ball rail system. The MathCAD application was developed in order to perform specific calculation for servomotor's thermal energy dissipation and maximum operating temperature evaluation, and allows to perform the assisted final check and optimum selection of the electrical driving servomotors based on these results. The paper presents, through some screenshots from running the MathCAD application, the computer assisted evaluation procedure and results of the brushless servomotor's thermal behavior analysis corresponding to analyzed NC axis (included in the experimental stand).
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Xin, Yang, Salvador Martinez Rivadeneira, Guido Grundmeier, Mario Castro, and Adrian Keller. "Self-assembly of highly ordered DNA origami lattices at solid-liquid interfaces by controlling cation binding and exchange." Nano Research 13, no. 11 (August 22, 2020): 3142–50. http://dx.doi.org/10.1007/s12274-020-2985-4.

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Abstract The surface-assisted hierarchical self-assembly of DNA origami lattices represents a versatile and straightforward method for the organization of functional nanoscale objects such as proteins and nanoparticles. Here, we demonstrate that controlling the binding and exchange of different monovalent and divalent cation species at the DNA-mica interface enables the self-assembly of highly ordered DNA origami lattices on mica surfaces. The development of lattice quality and order is quantified by a detailed topological analysis of high-speed atomic force microscopy (HS-AFM) images. We find that lattice formation and quality strongly depend on the monovalent cation species. Na+ is more effective than Li+ and K+ in facilitating the assembly of high-quality DNA origami lattices, because it is replacing the divalent cations at their binding sites in the DNA backbone more efficiently. With regard to divalent cations, Ca2+ can be displaced more easily from the backbone phosphates than Mg2+ and is thus superior in guiding lattice assembly. By independently adjusting incubation time, DNA origami concentration, and cation species, we thus obtain a highly ordered DNA origami lattice with an unprecedented normalized correlation length of 8.2. Beyond the correlation length, we use computer vision algorithms to compute the time course of different topological observables that, overall, demonstrate that replacing MgCl2 by CaCl2 enables the synthesis of DNA origami lattices with drastically increased lattice order.
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Nicolescu, Florin Adrian, Georgia Cezara Avram, Andrei Mario Ivan, and Adrian Theodor Mantea. "Computer Assisted Selection of Servomotor Driving System for Linear Motion NC Axis Experimental Stand." Applied Mechanics and Materials 762 (May 2015): 61–66. http://dx.doi.org/10.4028/www.scientific.net/amm.762.61.

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The paper presents the works performed by the authors in the field of structural and functional optimization numerically controlled (NC) axes. The study includes two computing applications developed by second author of the paper in a PhD thesis related on NC axes’ structural and functional optimization. The first computing application is used for calculating the total reflected inertia of a linear motion NC axis (total inertial loads' reducing on the driving motor's shaft level). The second computing application is used for both preliminary selection of the driving servomotor (by checking first the accomplishment of the kinematic criterion) and a secondary selection of the electric motor (by checking in a second stage the accomplishment of the static and dynamic criterion). By mean of both software applications optimal matching of servomotor driving system with available NC axis mechanical structure may be determined. The analyzed linear motion NC axis is part of an experimental stand (existing in the MMS department from EMTS faculty), that supplementary to the driving servomotor, includes a belt drive transmission, a ball screw - bearings assembly and a driven element guided by ball rail system.
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Bendemra, Hamza, Toufik Al Khawli, Muddasar Anwar, Dewald Swart, and Cesare Stefanini. "Force sensing drill jig for robotic assisted drilling." Industrial Robot: An International Journal 45, no. 2 (March 19, 2018): 181–92. http://dx.doi.org/10.1108/ir-11-2017-0208.

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Purpose The purpose of this paper is to present a novel force sensing jig for robot-assisted drilling used to drill holes for the fastening of floating nut plates in aircraft assembly. Design/methodology/approach The paper describes the drill jig, which consists of a parallel gripper, peg-in-hole pins and a back-plate with a recess where a Polydimethylsiloxane cone is placed on top of a force sensor. As the jig approaches the part, the force sensor registers the applied force until it reaches steady state, which indicates full contact between the jig and the part. The peg-in-hole pins then lock into a pre-existing hole, which provides a mechanical reference, and the support plate provides back support during drilling. Findings Positional accuracy and the repeatability of the system were successfully placed within the specification for accuracy and repeatability (0.1 mm tolerance and 0.2 mm tolerance, respectively). Practical implications The drill jig can be integrated into existing robot drilling solutions and modified for specific applications. The integration of the force sensor provides data for engineers to monitor and analyze forces during drilling. The design of the force sensing drill jig is particularly suited to industrial prototype robot drilling end-effectors for small and medium manufacturers. Originality/value The key novelties of this drilling jig are in the compact assembly, modular design and inclusion of force sensing and back support features.
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ŻOCHOWSKI, Tomasz, and Artur OLSZEWSKI. "THEORETICAL AND EXPERIMENTAL INVESTIGATION OF THIN-WALLED BEARING SHELL’S DESIGN PARAMETERS AND ASSEMBLY CONDITIONS ON THE HOLDING TORQUE INSIDE A HOUSING BORE OF A CONNECTING ROD." Tribologia 287, no. 5 (October 31, 2019): 125–33. http://dx.doi.org/10.5604/01.3001.0013.6569.

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The aim of the work was the experimental and theoretical evaluation of the influence of the most important parameters determining the holding torque of a thin-walled bearing shell inside a housing bore of a connecting rod. The main investigated parameters were defined by authors experience in this field. In the first stage of research, a special test stand was designed in order to allow measuring the real values of the friction torque for different variants of bearing shell geometries and assembly conditions, additionally analysing the influence of the locking lip. Subsequently, theoretical computer-assisted FEM simulations were performed.
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Chen, Yi-Min, Chun-Hui Yu, Chi-Chuan Hwang, and Tsunglin Liu. "OMACC: an Optical-Map-Assisted Contig Connector for improving de novo genome assembly." BMC Systems Biology 7, Suppl 6 (2013): S7. http://dx.doi.org/10.1186/1752-0509-7-s6-s7.

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31

Birk, D. E., J. F. Southern, E. I. Zycband, J. T. Fallon, and R. L. Trelstad. "Collagen fibril bundles: a branching assembly unit in tendon morphogenesis." Development 107, no. 3 (November 1, 1989): 437–43. http://dx.doi.org/10.1242/dev.107.3.437.

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The assembly, deposition and organization of collagen fibril bundles and their composite fibrils were studied during morphogenesis of the chick embryo tendon using electron microscopy, serial sections and computer-assisted three-dimensional reconstruction techniques. The 14-day chick embryo is a stage when tendon architecture is being established and rapid changes in the mechanical properties occur between days 14 and 17 of development. Tendon matrix structure develops from discrete subunits, bundles of collagen fibrils. The bundles branch; undergo a gradual rotation over several micrometers; are intimately associated with the cellular elements of the developing tendon; and form arborizing networks within and among fascicles. The organization of discrete fibril segments into bundles, during the establishment of tendon architecture and function, where the segmental fibrillar components could interact with the interfibrillar matrix as well as with adjacent fibrils would contribute to the stabilization of this structure. The observed gradual rotation of the bundles would serve to stabilize the immature bundle through the physical twining of the composite fibrils while the extensive branching of the bundles observed at 14-days of development and their intimate association with the cellular elements would provide a higher order of structure stabilization.
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Sang Yanxia, Zhou Tianhong, He Yan, and Chen Qiang. "Surface-Enhanced Raman Scattering Spectroscopy Based on Electrostatically Assisted PAMAM-Functionalized Surface-Assembly of Gold Nanoparticles." INTERNATIONAL JOURNAL ON Advances in Information Sciences and Service Sciences 5, no. 2 (January 31, 2013): 642–51. http://dx.doi.org/10.4156/aiss.vol5.issue2.81.

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33

Raffaeli, Roberto, Maura Mengoni, and Michele Germani. "Improving the link between computer-assisted design and configuration tools for the design of mechanical products." Artificial Intelligence for Engineering Design, Analysis and Manufacturing 27, no. 1 (January 15, 2013): 51–64. http://dx.doi.org/10.1017/s0890060412000388.

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AbstractThe competitive market forces companies to offer tailored products to meet specific customer needs. To avoid wasting time, design efforts generally address the configuration of existing solutions, without producing substantial design modifications. Configuration tools are used to achieve customized products starting from a common platform. Many approaches have been successfully proposed in literature to configure products. However, in the mechanical field they need further investigation in order to be efficiently linked to computer-aided design technologies. Research is focused on tools and methods to automatically produce geometrical models and improve the flexibility of the continuous product updating process. In this context, this paper aims to combine product configuration approaches with design automation techniques in order to support design activities of products to fulfill specific requirements. The approach is based on entities called configurable virtual prototypes. Three different domains are managed and connected via configurable virtual prototypes: product specifications, geometrical data, and product knowledge. In particular, geometry recognition rules are used to identify the parameterization of parts and the assembly mating constraints. The approach is exemplified through an industrial case study where a tool has been developed on the basis of the described method. Advantages of the system are shown in terms of achieved product configuration efficiency.
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Mchenya, Jacob M., Sheng Zhuo Zhang, and Song Jing Li. "Visualization of Flow-Field between the Flapper and Nozzle in a Hydraulic Servo-Valve." Advanced Materials Research 402 (November 2011): 407–11. http://dx.doi.org/10.4028/www.scientific.net/amr.402.407.

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In order to understand the mechanism and get rid of the high-frequency self-excited noise in a hydraulic servo-valve, in this paper, the flow field distribution in the pilot stage of a hydraulic flapper-nozzle servo-valve is investigated. An assembly is prepared representing the construction and working principle of the flow field inside the pilot stage of a hydraulic flapper-nozzle servo-valve. A method of visualization is developed by taking videos for the flow field inside the transparent assembly with a high speed video camera. In this study, at different inlet pressure the high speed video camera was utilized for flow visualization together with computer-assisted image measurement. The shape of the jet flow, the cavitations and vortex flow inside the flow field can be visualized clearly. The proposed method enables to analyze the flow-field in the pilot stage of a hydraulic flapper-nozzle servo-valve by giving useful information for better design.
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35

Roy, B., and H. H. Asada. "Nonlinear Feedback Control of a Gravity-Assisted Underactuated Manipulator With Application to Aircraft Assembly." IEEE Transactions on Robotics 25, no. 5 (October 2009): 1125–33. http://dx.doi.org/10.1109/tro.2009.2025067.

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36

CHERAGHI, S. HOSSEIN, P. J. EGBELU, and E. A. LEHTIHET. "Modelling and performance characterization of vision-assisted robotic cell for printed circuit board assembly." International Journal of Computer Integrated Manufacturing 8, no. 5 (September 1995): 381–90. http://dx.doi.org/10.1080/09511929508944665.

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37

Hashimoto, Masao S., Yasuko Tanaka, Hitoshi Sasabuchi, and Chutetsu F. Hattori. "A computer-assisted structure elucidation scheme based upon the pattern of assembly of peaks in carbon-13/ proton NMR spectra." Chemometrics and Intelligent Laboratory Systems 6, no. 2 (July 1989): 143–55. http://dx.doi.org/10.1016/0169-7439(87)80056-4.

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38

DeBarry, Jeremy D., Renyi Liu, and Jeffrey L. Bennetzen. "Discovery and assembly of repeat family pseudomolecules from sparse genomic sequence data using the Assisted Automated Assembler of Repeat Families (AAARF) algorithm." BMC Bioinformatics 9, no. 1 (2008): 235. http://dx.doi.org/10.1186/1471-2105-9-235.

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39

Van Toan, Nguyen, Masaya Toda, and Takahito Ono. "High Aspect Ratio Silicon Structures Produced via Metal-Assisted Chemical Etching and Assembly Technology for Cantilever Fabrication." IEEE Transactions on Nanotechnology 16, no. 4 (July 2017): 567–73. http://dx.doi.org/10.1109/tnano.2016.2645781.

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40

N. Hula, Ibnu Rawandhy, Moh Zulkifli Paputungan, and Ana Mariana. "PENGEMBANGAN HYBRID LEARNING BERBASIS APLIKASI COMPUTER ASSITED TEST (CAT) PADA PROGRAM ARABIC PROFICIENCY TEST." Tadbir: Jurnal Manajemen Pendidikan Islam 9, no. 1 (March 22, 2021): 103–25. http://dx.doi.org/10.30603/tjmpi.v9i1.2063.

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This study aims to develop Hybrid Learning based on the Computer Assisted Test (CAT) application in the Arabic Proficiency Test (APT) program.The method used was Research and Development with the ADDIE instructional design model (Analyze, Design, Develop, Implement and Evaluate), with development stages (concept, design, material collecting, assembly, testing and distribution). The results showed that the development of Hybrid Learning based on CAT application can be used in the Arabic Proficiency Test (APT) program which contains three language competency tests, (istima, tarakib and Qira’ah) and fulfills several aspects; 1) Self Instructional, 2) Self Instructional, 3) Self Contained, 4) Standalone, 5) User Friendly, and 6) Adaptive to technological developments. The results of the CAT-APT application trial in a limited group obtained a score of 80 (good) to 88 (very good), in the media validation test the score was 80 (good) to 86 (very good), the programming validation test and a score of 80 (good) to 88 (very good), while in the testing on the tester, the pretest score had not yet reached the advanced level, while in the posttest there were 9 testers who reached the advanced score.
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41

BOUYAKHF, E. H. "AN APPROACH FOR RECOGNIZING AND LOCATING OVERLAPPING INDUSTRIAL PARTS." International Journal of Pattern Recognition and Artificial Intelligence 02, no. 04 (December 1988): 673–89. http://dx.doi.org/10.1142/s021800148800042x.

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A new method recognizing and locating partially occluded two-dimensional parts is presented. The objects are described by a set of segments derived form the polygonal coding of their contours, and by the geometrical relationships between the segments. Rewriting rules are used to improve the stability of the polygonal coding. The identification process utilizes a robust hypothesis generator, from which the segment research assisted by the spatial relationship is propagated into the scene. The originality of this method relies mainly on the use of structural relationships between the segments to select the robust initialization hypotheses, and the use of structural research to achieve hypothesis propagation. These last two points with the use of a hash-coding technique to improve the location of predicted segments, greatly reduce the combinatories and make the algorithm particularly rapid and effective. This approach is integrated within a vision system of a Flexible Assembly Workcell to accomplish the automatic assembly of partially overlapping parts.
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42

Oluniyi, Paul E., Fehintola Ajogbasile, Judith Oguzie, Jessica Uwanibe, Adeyemi Kayode, Anise Happi, Alphonsus Ugwu, et al. "VGEA: an RNA viral assembly toolkit." PeerJ 9 (September 6, 2021): e12129. http://dx.doi.org/10.7717/peerj.12129.

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Next generation sequencing (NGS)-based studies have vastly increased our understanding of viral diversity. Viral sequence data obtained from NGS experiments are a rich source of information, these data can be used to study their epidemiology, evolution, transmission patterns, and can also inform drug and vaccine design. Viral genomes, however, represent a great challenge to bioinformatics due to their high mutation rate and forming quasispecies in the same infected host, bringing about the need to implement advanced bioinformatics tools to assemble consensus genomes well-representative of the viral population circulating in individual patients. Many tools have been developed to preprocess sequencing reads, carry-out de novo or reference-assisted assembly of viral genomes and assess the quality of the genomes obtained. Most of these tools however exist as standalone workflows and usually require huge computational resources. Here we present (Viral Genomes Easily Analyzed), a Snakemake workflow for analyzing RNA viral genomes. VGEA enables users to map sequencing reads to the human genome to remove human contaminants, split bam files into forward and reverse reads, carry out de novo assembly of forward and reverse reads to generate contigs, pre-process reads for quality and contamination, map reads to a reference tailored to the sample using corrected contigs supplemented by the user’s choice of reference sequences and evaluate/compare genome assemblies. We designed a project with the aim of creating a flexible, easy-to-use and all-in-one pipeline from existing/stand-alone bioinformatics tools for viral genome analysis that can be deployed on a personal computer. VGEA was built on the Snakemake workflow management system and utilizes existing tools for each step: fastp (Chen et al., 2018) for read trimming and read-level quality control, BWA (Li & Durbin, 2009) for mapping sequencing reads to the human reference genome, SAMtools (Li et al., 2009) for extracting unmapped reads and also for splitting bam files into fastq files, IVA (Hunt et al., 2015) for de novo assembly to generate contigs, shiver (Wymant et al., 2018) to pre-process reads for quality and contamination, then map to a reference tailored to the sample using corrected contigs supplemented with the user’s choice of existing reference sequences, SeqKit (Shen et al., 2016) for cleaning shiver assembly for QUAST, QUAST (Gurevich et al., 2013) to evaluate/assess the quality of genome assemblies and MultiQC (Ewels et al., 2016) for aggregation of the results from fastp, BWA and QUAST. Our pipeline was successfully tested and validated with SARS-CoV-2 (n = 20), HIV-1 (n = 20) and Lassa Virus (n = 20) datasets all of which have been made publicly available. VGEA is freely available on GitHub at: https://github.com/pauloluniyi/VGEA under the GNU General Public License.
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43

Peng, Yuan-Chih, Shuyang Chen, Devavrat Jivani, John Wason, William Lawler, Glenn Saunders, Richard J. Radke, Jeff Trinkle, Shridhar Nath, and John T. Wen. "Sensor-Guided Assembly of Segmented Structures with Industrial Robots." Applied Sciences 11, no. 6 (March 17, 2021): 2669. http://dx.doi.org/10.3390/app11062669.

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This paper presents a robotic assembly methodology for the manufacturing of large segmented composite structures. The approach addresses three key steps in the assembly process: panel localization and pick-up, panel transport, and panel placement. Multiple stationary and robot-mounted cameras provide information for localization and alignment. A robot wrist-mounted force/torque sensor enables gentle but secure panel pick-up and placement. Human-assisted path planning ensures reliable collision-free motion of the robot with a large load in a tight space. A finite state machine governs the process flow and user interface. It allows process interruption and return to the previous known state in case of error condition or when secondary operations are needed. For performance verification, a high resolution motion capture system provides the ground truth reference. An experimental testbed integrating an industrial robot, vision and force sensors, and representative laminated composite panels demonstrates the feasibility of the proposed assembly process. Experimental results show sub-millimeter placement accuracy with shorter cycle times, lower contact force, and reduced panel oscillation than manual operations. This work demonstrates the versatility of sensor guided robotic assembly operation in a complex end-to-end tasks using the open source Robot Operating System (ROS) software framework.
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44

Liu, Liying, Rui Cai, Yejing Wang, Gang Tao, Lisha Ai, Peng Wang, Meirong Yang, Hua Zuo, Ping Zhao, and Huawei He. "Polydopamine-Assisted Silver Nanoparticle Self-Assembly on Sericin/Agar Film for Potential Wound Dressing Application." International Journal of Molecular Sciences 19, no. 10 (September 21, 2018): 2875. http://dx.doi.org/10.3390/ijms19102875.

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Silver nanoparticles (AgNPs) are extensively applied for their broad-spectrum and excellent antibacterial ability in recent years. Polydopamine (PDA) has great advantages for synthesizing large amounts of AgNPs, as it has multiple sites for silver ion binding and phenolic hydroxyl structure to reduce silver ions to AgNPs. Here, we mixed sericin and agar solution and dried at 65 °C to prepare a sericin (SS)/Agar composite film, and then coated polydopamine (PDA) on the surface of SS/Agar film by soaking SS/Agar film into polydopamine solution, subsequently synthesizing high-density AgNPs with the assistance of PDA to yield antibacterial AgNPs-PDA- SS/Agar film. Scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) spectra indicated the successful synthesis of high-density AgNPs on the surface of PDA-SS/Agar film. PDA coating and AgNPs modification did not affect the structure of sericin and agar. Furthermore, water contact angle, water absorption and mechanical property analysis showed that AgNPs-PDA-SS/Agar film had excellent hydrophilicity and proper mechanical properties. Inhibition zone and growth curve assays suggested the prepared film had excellent and long-lasting antibacterial ability. In addition, it had excellent cytocompatibility on the fibroblast NIH/3T3 cells. The film shows great potential as a novel kind of wound dressing.
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45

Annamalai, Padmanaban, Swapna Apte, Stephan Wilkens, and A. L. N. Rao. "Deletion of Highly Conserved Arginine-Rich RNA Binding Motif in Cowpea Chlorotic Mottle Virus Capsid Protein Results in Virion Structural Alterations and RNA Packaging Constraints." Journal of Virology 79, no. 6 (March 15, 2005): 3277–88. http://dx.doi.org/10.1128/jvi.79.6.3277-3288.2005.

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ABSTRACT The N-proximal region of cowpea chlorotic mottle virus (CCMV) capsid protein (CP) contains an arginine-rich RNA binding motif (ARM) that is also found in the CPs of other members of Bromoviridae and in other RNA binding proteins such as the Tat and Rev proteins of human immunodeficiency virus. To assess the critical role played by this motif during encapsidation, a variant of CCMV RNA3 (C3) precisely lacking the ARM region (C3/Δ919) of its CP gene was constructed. The biology and the competence of the matured CP derived in vivo from C3/Δ919 to assemble and package progeny RNA was examined in whole plants. Image analysis and computer-assisted three-dimensional reconstruction of wild-type and mutant virions revealed that the CP subunits bearing the engineered deletion assembled into polymorphic virions with altered surface topology. Northern blot analysis of virion RNA from mutant progeny demonstrated that the engineered mutation down-regulated packaging of all four viral RNAs; however, the packaging effect was more pronounced on genomic RNA1 and RNA2 than genomic RNA3 and its CP mRNA. In vitro assembly assays with mutant CP subunits and RNA transcripts demonstrated that the mutant CP is inherently not defective in packaging genomic RNA1 (53%) and RNA2 (54%), but their incorporation into virions was competitively inhibited by the presence of other viral RNAs. Northern blot analysis of RNA encapsidation in vivo of two distinct bromovirus RNA3 chimeras, constructed by exchanging CPs having the Δ919 deletion, demonstrated that the role of the conserved N-terminal ARM in recognizing and packaging specific RNA is distinct for each virus.
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46

Tan, Xu, Xing Wang, He Hang, Dongyang Zhang, Ning Zhang, Ziyi Xiao, and Huijin Tao. "Self-assembly method assisted synthesis of g-C3N4/ZnO heterostructure nanocomposites with enhanced photocatalytic performance." Optical Materials 96 (October 2019): 109266. http://dx.doi.org/10.1016/j.optmat.2019.109266.

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47

Wan, Yi, Sijie Hou, Mengyao Guo, and Yanchun Fu. "Surface Properties of Spray-Assisted Layer-By-Layer ElectroStatic Self-Assembly Treated Wooden Take-Off Board." Applied Sciences 11, no. 2 (January 17, 2021): 836. http://dx.doi.org/10.3390/app11020836.

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Wooden take-off board is easy to crack, deform, discolor, and decay when it is used outdoors, which not only increases maintenance costs but also reduces its service life. Multifunctional coatings with UV-resistant, water-repellent, and flame-retardant properties were successfully obtained on the surface of a wooden take-off board substrate by spray-assisted layer-by-layer self-assembly. The coatings consisted of positively-charged chitosan, Al (OH)3, and negatively-charged sodium phytate through electrostatic adsorption several times. The treated wood exhibited high UV resistance, and the color remained constant after 720 hours of ultraviolet irradiation. The wettability of the wood surface after treatment became superhydrophobic, with initial static contact angles as high as 140°. In addition, limiting oxygen index and air exposure combustion tests were used to verify that chitosan, sodium phytate, and aluminum hydroxide could synergistically confer significant fire resistance to modified wood.
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48

William, R. V., A. Marikani, and K. Gangatharan. "Investigation of Multiferroic BiFeO3 Nanorods Using 2-MOE(C3H8O2)-Assisted Citrate Sol–Gel Method." International Journal of Nanoscience 18, no. 05 (July 24, 2019): 1850029. http://dx.doi.org/10.1142/s0219581x18500291.

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Bismuth ferrite (BiFeO[Formula: see text] nanorods have been prepared from 2-methoyethanol (2-MOE)-assisted sol–gel technique. Structure, dielectric, and magnetic properties of BiFeO3 nanorods are briefly discussed in this paper. Fourier-transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) results suggest that the BiFeO3 peaks calcined at 500∘C exhibit a distorted rhombohedral perovskite structure with the absence of other secondary phases like Bi2Fe4O9. Meanwhile, the BiFeO3 showed excellent photoluminescence (PL) behavior due to the transmission of electrons from conduction band to the valence band. Ferroelectric hysteresis loop of BiFeO3 shows an increase of coercivity from 5.5–6[Formula: see text][Formula: see text]C/cm2 in a frequency range of 6–12[Formula: see text]kHz. The magnetization measurement resulted in a well-saturated ferromagnetic behavior, and in addition, the temperature-dependent magnetization was discussed for BiFeO3 nanorod using superconducting quantum interference device (SQUID) method. The zero-field-cooled (ZFC) and field-cooled (FC) curves reveal spin-glass effect owing to size effects, spin exchange, and anisotropy of material assembly.
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Yu, Siming, Rong Wen, Haiyang Wang, Yongchao Zha, Lin Qiu, Bo Li, Wei Xue, and Dong Ma. "Chitosan-graft-Poly(l-lysine) Dendron-Assisted Facile Self-Assembly of Au Nanoclusters for Enhanced X-ray Computer Tomography Imaging and Precise MMP-9 Plasmid shRNA Delivery." Chemistry of Materials 31, no. 11 (May 14, 2019): 3992–4007. http://dx.doi.org/10.1021/acs.chemmater.9b00507.

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50

Anandaram, Mandayam N., B. A. Kagali, and S. P. Bhatnagar. "Design of a Small Automated Telescope for Indian Universities." Transactions of the International Astronomical Union 24, no. 3 (2001): 303–6. http://dx.doi.org/10.1017/s0251107x00000973.

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AbstractWe have constructed a computer controlled telescope using a 0.36-m f/11 Celestron optical tube assembly for teaching and research applications. We have constructed a heavy duty fork-type equatorial mount fitted with precision machined 24 inch drive disks for both axes. These are friction driven by stepper motors through one inch rollers. We have used an open loop control system triggerable by an ST-4 CCD camera to acquire and track any target object. Our telescope can home in on any target within a range of two arc-minutes. We have employed a commercial stepper motor controller card for which we have written a user friendly pc based telescope control software in C. Photometry using a solid state photometer, and imaging by an ST-6 CCD camera are possible.We consider that this project is suitable for those wishing to construct some parts of a telescope and understand the principles of operation. A simpler model of this telescope could use DC motors instead of stepper motors. We shall be happy to send our design diagrams and details to those interested. This project was funded by the DST, and was assisted by IUCAA, Pune.
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