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Journal articles on the topic 'Condensation de Friedländer'

Author: Grafiati
Published: 4 June 2021
Last updated: 12 February 2022

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1

Sabitha, Gowravaram, R. Satheesh Babu, B. V. Subba Reddy, and J. S. Yadav. "Microwave Assisted FriedläNder Condensation Catalyzed by Clay." Synthetic Communications 29, no. 24 (1999): 4403–8. http://dx.doi.org/10.1080/00397919908086603.

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2

Kumar, Dinesh, Asim Kumar, Mohammad Mohsin Qadri, Md Imam Ansari, Abhishek Gautam, and Asit K. Chakraborti. "In(OTf)3-catalyzed synthesis of 2-styryl quinolines: scope and limitations of metal Lewis acids for tandem Friedländer annulation–Knoevenagel condensation." RSC Advances 5, no. 4 (2015): 2920–27. http://dx.doi.org/10.1039/c4ra10613j.

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3

Godino-Ojer, Marina, Antonio J. López-Peinado, Francisco J. Maldonado-Hódar, Esther Bailón-García, and Elena Pérez-Mayoral. "Cobalt oxide–carbon nanocatalysts with highly enhanced catalytic performance for the green synthesis of nitrogen heterocycles through the Friedländer condensation." Dalton Transactions 48, no. 17 (2019): 5637–48. http://dx.doi.org/10.1039/c8dt04403a.

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A novel series of eco-sustainable catalysts developed by supporting CoO nanoparticles on different carbon supports, highly efficient in the synthesis of quinolines and naphthyridines, through the Friedländer condensation.
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4

Ziyadi, Hakimeh, and Akbar Heydari. "PVA/Fe(NO3)3 nanofiber mats: an efficient, heterogeneous and recyclable catalyst for the synthesis of quinolines via Friedländer annulations." RSC Adv. 4, no. 102 (2014): 58208–13. http://dx.doi.org/10.1039/c4ra07643e.

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PVA/Fe(NO<sub>3</sub>)<sub>3</sub> nanofiber mats are found to be a heterogeneous recyclable catalyst for the efficient synthesis of quinoline derivatives in the Friedländer condensation of 2-aminoarylketones with carbonyl compounds and β-keto esters.
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5

Comesse, Sébastien, and Adam Daïch. "An Unprecedented Straightforward Synthesis of Chiral Pyrrolo[3,4-b]quinolone and Pyrrolo[3,2-b]quinolone Backbones Starting fromtrans-4-Hydroxy-L-proline." Journal of Chemistry 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/1504682.

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The straightforward synthesis of pyrrolo[3,4-b]quinolone and pyrrolo[3,2-b]quinolone backbones, which can be found in molecules exhibiting anticancer activities, is presented. The key step of the process is an efficient and unprecedented Friedländer condensation between an oxoproline carbamate, obtained in 3 steps and good yield starting from commercially available and relatively cheaptrans-4-hydroxy-L-proline, and various 2-amino-substituted carbonyl derivatives. It was demonstrated that the formation of the two possible regioisomers was fully triggered by both the R substituent onto the 2-am
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6

Smuszkiewicz, A., E. Pérez-Mayoral, E. Soriano, et al. "Bifunctional mesoporous MCF materials as catalysts in the Friedländer condensation." Catalysis Today 218-219 (December 2013): 70–75. http://dx.doi.org/10.1016/j.cattod.2013.04.034.

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7

Muchowski, Joseph M., and Michael L. Maddox. "Concerning the mechanism of the Friedländer quinoline synthesis." Canadian Journal of Chemistry 82, no. 3 (2004): 461–78. http://dx.doi.org/10.1139/v03-211.

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Detailed experiments regarding the mechanism of the Friedländer synthesis of quinolines from o-aminobenzaldehydes and simple aldehydes or ketones are described. Under the basic or acidic conditions commonly used in this reaction, it is concluded that the first step involves a slow intermolecular aldol condensation of the aldehyde or ketone with the o-aminobenzaldehyde. The aldol adduct 5 generated in this manner then undergoes very rapid cyclization to 4, which subsequently loses water to produce the quinoline derivative 8. Both 5 and 4 are too short lived to be detectable (TLC), even when del
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8

Stockmann, Vegar, and Anne Fiksdahl. "Synthesis of novel 1,7-naphthyridines by Friedländer condensation of pyridine substrates." Journal of Heterocyclic Chemistry 48, no. 6 (2011): 1383–87. http://dx.doi.org/10.1002/jhet.657.

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9

Li, Yang, and Wentao Gao. "Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles." Beilstein Journal of Organic Chemistry 6 (October 8, 2010): 966–72. http://dx.doi.org/10.3762/bjoc.6.108.

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A simple and efficient synthesis of novel 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles, utilizing sodium ethoxide as a catalyst via a Friedländer condensation reaction between 3-acetyl-9-ethyl-9H-carbazole or 3,6-diacetyl-9-ethyl-9H-carbazole and β-aminoaldehydes or β-aminoketones is described. All of the title compounds were obtained in good yields of 52–72% and their structures were confirmed by IR, 1H NMR, MS, and elemental analysis.
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10

Rote, Ramhari V., Sandeep M. Bagul, Deepak P. Shelar, Sandeep R. Patil, Raghunath B. Toche, and Madhukar N. Jachak. "Synthesis of benzo[3,4-h][1,6]naphthyridines via Friedländer condensation with active methylenes." Journal of Heterocyclic Chemistry 48, no. 2 (2010): 301–7. http://dx.doi.org/10.1002/jhet.391.

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11

Ren, Lei, Tao Lei, Jia-Xi Ye, and Liu-Zhu Gong. "Step-Economical Synthesis of Tetrahydroquinolines by Asymmetric Relay Catalytic Friedländer Condensation/Transfer Hydrogenation." Angewandte Chemie 124, no. 3 (2011): 795–98. http://dx.doi.org/10.1002/ange.201106808.

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12

Ren, Lei, Tao Lei, Jia-Xi Ye, and Liu-Zhu Gong. "Step-Economical Synthesis of Tetrahydroquinolines by Asymmetric Relay Catalytic Friedländer Condensation/Transfer Hydrogenation." Angewandte Chemie International Edition 51, no. 3 (2011): 771–74. http://dx.doi.org/10.1002/anie.201106808.

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13

Gao, Wentao, Jia Liu, Yun Jiang, and Yang Li. "First synthesis of 2-(benzofuran-2-yl)-6,7-methylene dioxyquinoline-3-carboxylic acid derivatives." Beilstein Journal of Organic Chemistry 7 (February 15, 2011): 210–17. http://dx.doi.org/10.3762/bjoc.7.28.

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A facile and inexpensive synthesis of a series of novel methylenedioxy-bearing 2-(benzofuran-2-yl)-quinoline-3-carboxylic acid derivatives 3a–h via the one-pot reaction of ethyl 2-chloromethyl-6,7-methylenedioxyquinoline-3-carboxylate (5) with various substituted salicylaldehydes 6a–g as well as 2-hydroxy-1-naphthaldehyde (6h) is described. Substrate 5 was synthesized by the Friedländer condensation reaction of 2-amino-4,5-methylenedioxybenzaldehyde (4) with ethyl 4-chloro-3-oxobutanoate using KHSO4 as catalyst under ultrasound irradiation conditions. The targeted compounds 3a–h were obtained
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14

Kozubková, Zuzana, Michal Rouchal, Marek Nečas, and Robert Vícha. "Novel Route to 4-(Adamantan-1-yl)quinoline Derivatives Based on the Friedländer Condensation." Helvetica Chimica Acta 95, no. 6 (2012): 1003–17. http://dx.doi.org/10.1002/hlca.201100432.

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15

Nedeltchev, Alexi K., Haesook Han, and Pradip K. Bhowmik. "Photoactive amorphous molecular materials based on quinoline amines and their synthesis by Friedländer condensation reaction." Tetrahedron 66, no. 48 (2010): 9319–26. http://dx.doi.org/10.1016/j.tet.2010.09.108.

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16

Bhowmik, Pradip K., Alexi K. Nedeltchev, Haesook Han, et al. "Photoactive amorphous molecular materials based on bisquinoline diamines and their synthesis by Friedländer condensation reaction." Journal of Photochemistry and Photobiology A: Chemistry 283 (June 2014): 45–55. http://dx.doi.org/10.1016/j.jphotochem.2014.03.021.

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17

Dennison, Genevieve H., Jonathan M. White, and Martin R. Johnston. "Efficient access to Unsymmetrically 3-Substituted-1,10-Phenanthrolines via Microwave Assisted Friedländer Condensation with Aldehydes." ChemistrySelect 1, no. 20 (2016): 6434–37. http://dx.doi.org/10.1002/slct.201601576.

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18

Bañón-Caballero, Abraham, Gabriela Guillena, and Carmen Nájera. "Solvent-Free Enantioselective Friedländer Condensation with Wet 1,1′-Binaphthalene-2,2′-diamine-Derived Prolinamides as Organocatalysts." Journal of Organic Chemistry 78, no. 11 (2013): 5349–56. http://dx.doi.org/10.1021/jo400522m.

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19

Godino-Ojer, Marina, Antonio J. López-Peinado, Rosa M. Martín-Aranda, Jacek Przepiórski, Elena Pérez-Mayoral, and Elena Soriano. "Eco-Friendly Catalytic Systems Based on Carbon-Supported Magnesium Oxide Materials for the Friedländer Condensation." ChemCatChem 6, no. 12 (2014): 3440–47. http://dx.doi.org/10.1002/cctc.201402602.

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20

Dridi, Khaireddine Mohamed, Ridha Ben Said, Youssef Arfaoui, and Abdullah Sulaiman Al-Ayed. "Activated bentonite promoted Friedländer condensation reactions: Synthesis of thieno[2,3-b]quinolinones and tacrines analogues derivatives." European Journal of Chemistry 4, no. 3 (2013): 216–19. http://dx.doi.org/10.5155/eurjchem.4.3.216-219.788.

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21

Das, Aniruddha, Nagaraj Anbu, Perumal Varalakshmi, Amarajothi Dhakshinamoorthy, and Shyam Biswas. "A hydrazine functionalized UiO-66(Hf) metal–organic framework for the synthesis of quinolines via Friedländer condensation." New Journal of Chemistry 44, no. 26 (2020): 10982–88. http://dx.doi.org/10.1039/d0nj01891k.

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A hydrazine functionalized Hf MOF was used as a heterogeneous catalyst for the synthesis of quinolone scaffolds with high yields. The catalyst showed a broad substrate scope and excellent recyclability.
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22

Le, Zhang-Gao, Meng Liang, Zhong-Sheng Chen, Sui-Hong Zhang та Zong-Bo Xie. "Ionic Liquid as an Efficient Medium for the Synthesis of Quinoline Derivatives via α-Chymotrypsin-Catalyzed Friedländer Condensation". Molecules 22, № 5 (2017): 762. http://dx.doi.org/10.3390/molecules22050762.

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23

Jachak, Madhukar N., Appasaheb B. Avhale, Chanda D. Tantak, Raghunath B. Toche, Claudia Reidlinger та Wolfgang Stadlbauer. "Friedländer condensation of 5-aminopyrazole-4-carbaldehydes with reactive α-methylene ketones: Synthesis of pyrazolo[3,4-b]pyridines". Journal of Heterocyclic Chemistry 42, № 7 (2005): 1311–19. http://dx.doi.org/10.1002/jhet.5570420710.

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24

Seidel, Daniel, and Le Li. "Origins of Enantioselectivity in Proline-Catalyzed Friedländer Condensations of 4-Substituted Cyclohexanones." Synthesis 2011, no. 12 (2011): 1853–58. http://dx.doi.org/10.1055/s-0030-1260526.

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25

Ren, Lei, Tao Lei, and Liu-Zhu Gong. "Brønsted acid-catalyzed enantioselective Friedländer condensations: achiral amine promoter plays crucial role in the stereocontrol." Chemical Communications 47, no. 42 (2011): 11683. http://dx.doi.org/10.1039/c1cc14873g.

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26

"Asymmetric Relay Friedländer Condensation-Transfer Hydrogenation." Synfacts 8, no. 04 (2012): 0419. http://dx.doi.org/10.1055/s-0031-1290523.

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27

Costa, Jessie S. da, Diego S. Pisoni, Claudia B. da Silva, Cesar L. Petzhold, Dennis Russowsky, and Marco A. Ceschi. "Lewis acid promoted Friedländer condensation reactions between anthranilonitrile and ketones for the synthesis of tacrine and its analogues." Journal of the Brazilian Chemical Society, 2006. http://dx.doi.org/10.1590/s0103-50532009000800009.

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28

"Phosphoric Acid Catalyzed Enantioselective Friedländer Condensations." Synfacts 2011, no. 12 (2011): 1368. http://dx.doi.org/10.1055/s-0031-1289380.

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