Relevant bibliographies by topics / Conditioning activity

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Conditioning activity'

Author: Grafiati
Published: 19 February 2023

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Journal articles on the topic "Conditioning activity"

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Duvarci, S., D. Popa, and D. Pare. "Central Amygdala Activity during Fear Conditioning." Journal of Neuroscience 31, no. 1 (January 5, 2011): 289–94. http://dx.doi.org/10.1523/jneurosci.4985-10.2011.

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Rorick-Kehn, Linda M., and Joseph E. Steinmetz. "Amygdalar unit activity during three learning tasks: Eyeblink classical conditioning, Pavlovian fear conditioning, and signaled avoidance conditioning." Behavioral Neuroscience 119, no. 5 (2005): 1254–76. http://dx.doi.org/10.1037/0735-7044.119.5.1254.

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Ogaya, Shinya, Hidetoshi Takahashi, Mayuko Shioiri, Akira Saito, and Yasutomo Okajima. "Changes in Electromyographic Activity after Conditioning Contraction." Journal of Physical Therapy Science 24, no. 10 (2012): 979–83. http://dx.doi.org/10.1589/jpts.24.979.

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HIRAMOTO, RAYMOND N., NANCY S. HIRAMOTO, H. BRENT SOLVASON, and VITHAL K. GHANTA. "Regulation of Natural Immunity (NK Activity) by Conditioning." Annals of the New York Academy of Sciences 496, no. 1 Neuroimmune I (May 1987): 545–52. http://dx.doi.org/10.1111/j.1749-6632.1987.tb35812.x.

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Tapp, Walter, Richard Servatius, Janet Hunt, and Donald A. Powell. "Vagal activity predicts eyeblink conditioning in human subjects." NeuroReport 8, no. 5 (March 1997): 1203–7. http://dx.doi.org/10.1097/00001756-199703240-00029.

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Chabaud, Marie-Ange, Jean-Marc Devaud, Minh-Hà Pham-Delègue, Thomas Preat, and Laure Kaiser. "Olfactory conditioning of proboscis activity in Drosophila melanogaster." Journal of Comparative Physiology A 192, no. 12 (September 9, 2006): 1335–48. http://dx.doi.org/10.1007/s00359-006-0160-3.

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Kobayashi, Shunsuke, Wolfram Schultz, and Masamichi Sakagami. "Operant Conditioning of Primate Prefrontal Neurons." Journal of Neurophysiology 103, no. 4 (April 2010): 1843–55. http://dx.doi.org/10.1152/jn.00173.2009.

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An operant is a behavioral act that has an impact on the environment to produce an outcome, constituting an important component of voluntary behavior. Because the environment can be volatile, the same action may cause different consequences. Thus to obtain an optimal outcome, it is crucial to detect action–outcome relationships and adapt the behavior accordingly. Although prefrontal neurons are known to change activity depending on expected reward, it remains unknown whether prefrontal activity contributes to obtaining reward. We investigated this issue by setting variable relationships between levels of single-neuron activity and rewarding outcomes. Lateral prefrontal neurons changed their spiking activity according to the specific requirements for gaining reward, without the animals making a motor response. Thus spiking activity constituted an operant response. Data from a control task suggested that these changes were unlikely to reflect simple reward predictions. These data demonstrate a remarkable capacity of prefrontal neurons to adapt to specific operant requirements at the single-neuron level.
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Siegel, Jennifer J., Brian Kalmbach, Raymond A. Chitwood, and Michael D. Mauk. "Persistent activity in a cortical-to-subcortical circuit: bridging the temporal gap in trace eyelid conditioning." Journal of Neurophysiology 107, no. 1 (January 2012): 50–64. http://dx.doi.org/10.1152/jn.00689.2011.

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We have addressed the source and nature of the persistent neural activity that bridges the stimulus-free gap between the conditioned stimulus (CS) and unconditioned stimulus (US) during trace eyelid conditioning. Previous work has demonstrated that this persistent activity is necessary for trace eyelid conditioning: CS-elicited activity in mossy fiber inputs to the cerebellum does not extend into the stimulus-free trace interval, which precludes the cerebellar learning that mediates conditioned response expression. In behaving rabbits we used in vivo recordings from a region of medial prefrontal cortex (mPFC) that is necessary for trace eyelid conditioning to test the hypothesis that neurons there generate activity that persists beyond CS offset. These recordings revealed two patterns of activity during the trace interval that would enable cerebellar learning. Activity in some cells began during the tone CS and persisted to overlap with the US, whereas in other cells, activity began during the stimulus-free trace interval. Injection of anterograde tracers into this same region of mPFC revealed dense labeling in the pontine nuclei, where recordings also revealed tone-evoked persistent activity during trace conditioning. These data suggest a corticopontine pathway that provides an input to the cerebellum during trace conditioning trials that bridges the temporal gap between the CS and US to engage cerebellar learning. As such, trace eyelid conditioning represents a well-characterized and experimentally tractable system that can facilitate mechanistic analyses of cortical persistent activity and how it is used by downstream brain structures to influence behavior.
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Weible, Aldis P., Craig Weiss, and John F. Disterhoft. "Activity Profiles of Single Neurons in Caudal Anterior Cingulate Cortex During Trace Eyeblink Conditioning in the Rabbit." Journal of Neurophysiology 90, no. 2 (August 2003): 599–612. http://dx.doi.org/10.1152/jn.01097.2002.

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Acquisition of trace eyeblink conditioning involves the association of a conditioned stimulus (CS) with an unconditioned stimulus (US) separated by a stimulus-free trace interval. This form of conditioning is dependent upon the hippocampus and the caudal anterior cingulate cortex (AC), in addition to brain stem and cerebellar circuitry. Hippocampal involvement in trace eyeblink conditioning has been studied extensively, but the involvement of caudal AC is less well understood. In the present study, we compared neuronal responses from rabbits given either paired (trace conditioning) or unpaired (pseudoconditioning) presentations of the CS and US. Presentation of the CS elicited significant increases in neuronal activity at the onset of both trace conditioning and pseudoconditioning. A robust CS-elicited neuronal response persisted throughout the first 2 days of trace conditioning, declining gradually across subsequent training sessions. In contrast, the magnitude of the CS-elicited excitatory response during pseudoconditioning began to decline within the first 10 trials. Neurons exhibiting excitatory responses to the CS during trace conditioning also exhibited excitatory responses to the US that were significantly greater in magnitude than US-elicited responses during pseudoconditioning. CS-elicited decreases in neuronal activity became more robust over the course of trace conditioning compared to pseudoconditioning. Reductions in activity during the CS interval consistently preceded excitation in both training groups, suggesting that the CS-elicited decreases in neuronal activity may serve to increase the signal-to-noise ratio of the excitatory response to the tone. Taken together, these data suggest that the caudal AC is involved early in trace eyeblink conditioning and that maintenance of the CS-elicited excitatory response may serve to signal the salience of the tone.
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Navarro, Fernanda Keley Silva Pereira, and José Francisco Gonçalves Junior. "Effects of microbial conditioning and temperature on the leaf-litter shredding activity of Phylloicus sp." Acta Scientiarum. Biological Sciences 42 (July 6, 2020): e52919. http://dx.doi.org/10.4025/actascibiolsci.v42i1.52919.

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Few studies try to explain the effects in tropical lotic ecosystems of an increase in water temperature on the shredding activity of invertebrate shredders, particularly in association with the quality of the leaf litter and the degree of litter conditioning. Therefore, the aims of this study were as follows: i) to better understand how this key invertebrate shredder group affects the decomposition of different species of leaf litter under gradual increases in temperature and microbial conditioning; and ii) to verify the possible consequences on leaf mass loss (LML). Three species of leaf litter were used in two experiments. In experiment I, the litters of three species (Protium spruceanum, Richeria grandis and Inga laurina) at three conditioning levels (1, 7, 14 days) were tested under five different temperatures (20, 22, 24, 26 and 28°C). In experiment II, the leaf litters of three species were used, without conditioning, under four temperatures (20, 22, 26 and 27°C). The shredding performed by Phylloicus sp. was largely dependent on the lignin and cellulose concentrations in each leaf species, independent of conditioning. The presence or absence of conditioning may cause the shredders to use different energy compensation strategies in response to the temperature increases.
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Dissertations / Theses on the topic "Conditioning activity"

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Di, Federico Erica. "Complex mechanical conditioning of cell-seeded constructs can influence chondrocyte activity." Thesis, Queen Mary, University of London, 2014. http://qmro.qmul.ac.uk/xmlui/handle/123456789/7982.

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Articular cartilage represents a primary target for tissue engineering strategies as it does not functionally regenerate within the joint. Many tissue engineering approaches have focused on the in vitro generation of neo-cartilage using chondrocyte-seeded scaffolds. Several studies have reported the morphological appearance of native cartilage, although its functional competence has not been demonstrated. Accordingly, mechanical conditioning has often been introduced to enhance biosynthetic activity of chondrocytes within 3D constructs. However although this strategy has significantly up-regulated proteoglycan synthesis, its effects on the synthesis of the other major solid constituent, type II collagen, has been modest. Analyses of normal joint activities reveal that cartilage is subjected to shear superimposed on uniaxial compression. This complex mechanical state has motivated the design of a biaxial loading system intended for use in vitro to stimulated bovine chondrocytes seeded in agarose constructs. This necessitated the redesign of the construct from cylindrical morphology to accommodate shear loading. The experimental approach was complemented with the development of computational models, which permitted prediction of both cell distortion under biaxial loading regimens and nutrient diffusion within the 3D constructs. An initial study established the profile of proteoglycan and collagen synthesis in free swelling cultures up to day 12. The introduction of dynamic compression (15% strain, 1 Hz for 48 h) enhanced proteoglycan synthesis significantly. In addition, when dynamic shear (10%, 1 Hz) was superimposed on dynamic compression, total collagen synthesis was also up-regulated, within 3 days of culture, without compromising proteoglycan synthesis. Histological analysis revealed marked collagen deposition around individual chondrocytes. However, a significant proportion (50%) of collagen was released into the culture medium, suggesting that it was not fully processed. The overall biosynthetic activity was enhanced more when the biaxial stimulation was applied in a continuous mode as opposed to intermittent loading. The present work offers the potential for a more effective preconditioning of cell-seeded constructs with functional integrity intended for use to resolve defects in joint cartilage.
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O'Grady, Mathew. "Manipulating a conditioning activity to enhance potentiation and its application to jumping and sprinting performance." Thesis, Federtion University Australia, 2017. http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/165480.

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Post-activation potentiation (PAP) is the phenomenon where contractile history of a muscle may acutely increase voluntary performance of future contractions that are biomechanically similar (72). In order to exploit the PAP phenomenon, a conditioning activity (CA) is performed to enhance the performance of a subsequent skill. Throughout the literature, a common example of a CA is sets of heavy-loaded squats in order to potentiate subsequent jumping (31,33,39,57,83,116,151,163) or sprinting performance (15,28,39,99). Post-activation potentiation can be used either in a warm-up to acutely enhance performance for competition, or used within a resistance training session to enhance speed-strength, with the intention of producing a greater training stimulus for chronic adaptations. The major issue with the PAP literature is the inconsistent results from study to study. There are many examples within the research that show the positive effects of PAP (44,54,57,62,83,102,133,163), whilst many others have failed to find any increase in performance (42,47,56,81,112,123,141). The results have been inconsistent as the methodology between studies has varied dramatically. These differences include the warm-up used prior to testing sessions, changes in the type of CA (30,54,163), the intensity or load of the CA (19,21,33) and the rest period allocated between the CA and the performance of the skill. Furthermore, it seems that certain individuals respond better to a CA, with most of the literature suggesting that participant strength has a positive correlation with a potentiating response (15,31,44,116,128,129,163). Due to the vast differences in methodologies used throughout the potentiation literature, it is hard for coaches to identify the best practice in order to elicit a positive potentiating effect. Therefore, four studies were designed to address these current gaps within the potentiation literature in order to establish the best methodology to elicit a potentiating response. The first study sought to investigate whether a heavy half-squat CA could further improve jumping after an individualised optimal warm-up. As many of the warm-ups used prior to the baseline measurement in the potentiation research have been insufficient (30,44,69,71,88,102,111,115,140,143,158), it is plausible to suggest that improvements after a CA could be due to general mechanisms of a warm-up, rather than PAP. To investigate this, participants performed six different volumes of warm-ups on six separate days, followed by CMJ and DJ testing. After each participant completed the six warm-ups, their individual optimum warm-up was identified as the warm-up that produced the greatest CMJ relative peak power (RPP). On two separate sessions, a CA of four half-squats at a 5RM load was then added to each individual’s optimum warm-up and a sub-optimum warm-up. Countermovement jump tests were performed before the CA (pre) and then four and eight minutes after the CA. Drop jump testing was performed before the CA (pre) and then six and 10 minutes after the CA. When examining each post-test separately, no improvements in CMJ performance were identified. Furthermore, for both the optimum and sub-optimum warm-up conditions, DJ performance significantly decreased at all post-tests (p < 0.05). When each individuals best recovery period was considered (post-best), both the maximum and mean CMJ jump height significantly increased above baseline measures for the optimum warm-up condition. No other CMJ or DJ variable displayed any significant change after the addition of the CA for either condition. As significant increases in CMJ jump height were identified, the four half-squat CA with a 5RM load was used in the next investigation. Although each individual’s optimum warm-up volume varied, the moderate warm-up volume produced sufficient CMJ performance for all individuals. Considering the time required identifying each individuals optimum warm-up, the moderate warm-up was deemed sufficient and was used for the following studies. The second study of this thesis investigated the acute response of two different CA strategies. Both CAs included four half squats at a 5RM load, however, in one condition participants were instructed to perform the squat in a controlled manner, whilst in the second condition, they were instructed to lift the bar as fast as possible without losing contact with the ground. At any post-time (including post-best), no significant improvement were identified for any CMJ variable in either condition. Furthermore, DJ performance significantly decreased at all post-tests for the explosive CA condition. Although no significant improvements were identified, when each individual’s optimum recovery period was considered, CMJ jump height increased by 2.6% in the explosive CA condition, as opposed to 0.9% in the controlled CA condition. Because of this difference within the means of each condition, for the future studies throughout this thesis, participants were instructed to lift the bar as fast as possible during a heavy half-squat CA. The third study of this thesis compared different volumes of plyometric CAs (rebound jumps) to a CA involving heavy half-squats and assessed the effect each had on potentiating CMJ and sprinting performance. Past research had often used small amounts of plyometric contacts to potentiate future contractions (23,30,143,146,151), however, due to their short duration; they were often not successful in improving performance. For one condition, this study increased the repetitions of plyometric contacts in the CA, so that its duration matched the time under tension exhibited by the four half-squats with a 5RM load. Furthermore, two other plyometric CA conditions were included; one that matched half of the time under tension of the half-squats and one that involved only four repetitions of the rebound jump (match the amount of repetitions of the half-squat). No CA (plyometric or half-squat) displayed statistical significant improvements in CMJ or sprint performance at any post-test interval. For CMJ performance, although it did not significantly improve performance, generally the heavy half-squat CA had smaller decrements in performance than the plyometric CAs, hence the final investigation of this thesis focussed upon different heavy dynamic CAs in order to potentiate CMJ performance. The final study of this thesis firstly aimed to investigate the effect of three different types of half-squat CAs had on potentiating CMJ performance. This study also aimed to explore why certain individuals respond positively to a CA, whilst others respond in a negative manner. At the beginning of this study, participants completed a number of fitness performance tests, to assess each individual’s performance. Participants then assessed the effect of three different CAs on CMJ performance. These CAs included three repetitions of the half-squat with a 3RM load (3 @ 3RM), four repetitions with a 5RM load (4 @ 5RM) and then five repetitions with a 5RM load (5 @ 5RM). In terms of the entire population of the study, after each of the CAs, post-CMJ performance typically decreased across all rest periods, whilst any improvement in particular CMJ variables were considered to only be trivial in terms of effect size magnitudes. Despite this, multiple statistically significant positive correlations were evident between particular fitness qualities (absolute strength, CMJ RPP and aerobic capacity) and the change scores between pre and post-best CMJ performance after certain CAs. Therefore, the participants were median split in terms of each of the following fitness qualities to assess the relationship each quality has on potentiating CMJ performance. When the population was split in terms of absolute strength, the stronger participants significantly improved CMJ performance at their best recovery period after the performance of the 5 @ 5RM CA (three out of the four CMJ variables assessed significantly improved), whilst the weaker individuals showed no significant improvements. A similar trend was exhibited when the population was split in terms of CMJ RPP, with the more powerful individuals improving by small to moderate effect size magnitudes after the 5 @ 5RM CA, whilst the less powerful group did not. From the studies presented in the thesis, it can be concluded that certain recreationally resistance trained males can acutely enhance CMJ performance with the use of a heavy dynamic CA, even after pre-test performance has been optimised by a general warm-up. The optimum recovery period for the individual does need to be considered, as individuals require different amounts of rest to allow for an improvement in performance. Furthermore, the individual needs to have sufficient strength of the lower limbs in order to improve future contractions via the use of the heavy dynamic CA, as individuals with less strength do not improve post-CMJ performance after a CA. In terms of the type of CA used, heavy half-squat seem to be more effective than rebound jumps in order to potentiate CMJ performance. Furthermore, five repetitions with a 5RM load seems more effective than heavier CAs (3 @ 3RM) or ones that have less repetitions (4 @ 5RM) for this particular population.
Doctor of Philosophy
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Ågren, Thomas. "Erasing Fear : Effect of Disrupting Fear Memory Reconsolidation on Central and Peripheral Nervous System Activity." Doctoral thesis, Uppsala universitet, Institutionen för psykologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-180202.

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Fear memories, here defined as learned associations between a stimulus and a physiological fear reaction, are formed through fear conditioning. In animals, fear memories, present in the lateral amygdala, undergo reconsolidation after recall. Moreover, this reconsolidation process can be disrupted both pharmacologically and behaviourally, resulting in a reduced fear response to the stimulus. This thesis examines the attenuation of fear memories by disrupting reconsolidation in humans, using measures of both the central and peripheral nervous system activity. Serotonergic and dopaminergic genes have previously been tied to both fear conditioning and anxiety disorders, where fear conditioning mechanisms are important. In order to evaluate the possible role of fear memory reconsolidation mechanims in the effect on fear and anxiety by these genes, this thesis also compare the reconsolidation disruption effect between different serotonergic and dopaminergic genotypes. Study I examined the attentuation of fear memories by disrupting reconsolidation in humans using reacquisition as a measure of the return of fear. Moreover, study I investigated the impact of differences in serotonergic and dopaminergic alleles on this process. Study II examined the attentuation of fear memories by disrupting reconsolidation in humans using reinstatement as a measure of the return of fear. Study II also investigated the impact of differences in serotonergic and dopaminergic alleles on the process of fear memory reconsolidation. Study III used psychophysiology and fMRI to localize the functional neural activity mediating the fear memory reconsolidation disruption effect. In summary, this thesis provides evidence that fear memories are attenuated by reconsolidation disruption in humans and that serotonergic and dopaminergic alleles influence this process. Moreover, this thesis support that human fear memory reconsolidation is amygdala-dependent, suggesting an evolutionary shared memory mechanism.
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Alzate, Correa Diego Fernando. "Regulation of Suprachiasmatic Nucleus and Hippocampal Cellular Activity as a Function of Circadian Signaling." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1494196688129828.

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Olausson, Jesper. "Energy efficiency in a renovated modern office with activity-based work style." Thesis, Högskolan i Gävle, Energisystem och byggnadsteknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-30113.

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During renovation Ljusåret 2 was converted to a modern office with an activity based work style (ABW) with a Demand Controlled Volume (DCV) ventilation system connected to a closed-loop duct. Cooling is provided through air handling units and active water based beams, the underfloor heating system was kept. Written instruction and specification have been studied for the two different control systems Schneider EcoStructure and Lindinspect. Both control systems have been analyzed according to time schedule, set-point and process value by using different functions in software. To be able to perform a energy audit and look at indoor climate for Ljusåret 2 there have been studies according to underfloor heating, constructions of ventilation system, diversity factor for DCV, closed-loop-ducts, heat losses from ducts, cooling demand and energy certification. According to this audit, energy performance is calculated to 89.1 kWh/m2 according to building energy, activity energy is not audited or calculated. During design phase, an energy calculation was made by an energy consultant with the result of 81.3 kWh/m2. The estimated performance is a 9.6 % increase. This building is designed for Miljöbyggnad certification of level silver and should be ≤ 109 kWh/m2,year. According to audit and calculation for energy performance this level is possible to keep. The estimated energy performance have been calculated with only 4 month of statistics from January until April 2019 because Ljusåret 2 have just been renovated. District heating has been estimated through the energy signature by data from energy meter. Electrical components for the building have been measured and energy usage calculated. Energy produced by compression chiller have been estimated with calculated performance from design phase and adding heat transfer between rooms and supply ducts. Energy between rooms and supply ducts were not included in energy calculation during the design phase. According to the control system for the DCV system there have been some issues with high temperature in supply ducts even when they are supplied with 15 ºC from air- handling unit. There have been measurement to the ventilation system 5701-5704 that is connected to a close-loop duct with a result of temperatures between 15.2 ºC up to 21.4 ºC and the velocity has varied between 0.05-2.1 m/s in different measurement spots. This is an increase of 6.4 ºC. A heat transfer calculation have been made in Paroc Calculus to estimate heat transfer between room and supply ducts. The results of this calculation indicates the same level of temperature increases as when the system was measured. With no thermal insulation cooling capacity is lost to half after less than 5 m with a velocity of 0.2 m/s, after 15 m with a velocity of 1 m/s and 30 m with a velocity of 2 m/s . This should be compared with supply duct with 20 mm of thermal insulation that has lost its cooling capacity after less than 13 m with a velocity of 0.2 m/s, after 63 m with a velocity of 1 m/s and is increase with 4 ºC after 100 m with a velocity of 2 m/s. Using closed-loop ducts with velocity below 2.0 m/s and without thermal insulation combined with under tempered supply air is not a good combination. Even short length with low velocity and lack of thermal insulation is devastating because of heat transfer according to logarithmical temperature difference between room and supply ducts. A closed-loop duct is often designed as a pressure chamber and recommended when using DCV and/or VAV ventilation to avoid problems with noise and to be able to reduce the need of dampers. Problems with temperature increasing according to velocity in ducts must be taken in consideration. For Ljusåret 2 this will affect district heating usage where ducts are placed because underfloor heating must compensate heat transfer. Chilled water must be provided an extra time for rooms with both DCV and chilled beams and rooms with only DCV is less comfortable which they could been with a correct installation.
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Lima, Dartel Ferrari de. "Atividade física de adultos nas capitais brasileiras e no Distrito Federal: um estudo transversal." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5137/tde-09122014-115116/.

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INTRODUÇÃO: Existem dúvidas em relação à atividade física (AF) de adultos residentes nas capitais brasileiras e no Distrito Federal no que tange à organização e à execução desta prática. Neste estudo avaliamos a prevalência de AF segundo cada uma das principais diretrizes internacionais que recomendam a AF para a promoção da saúde e exploramos as divergências e consensos na classificação do nível da AF. Avaliamos também a associação entre características sociodemográficas e comportamentais com a prática da AF, como os principais componentes da AF se relacionam na determinação do nível da AF individual e descrevemos o padrão nos portadores de doenças crônicas não transmissíveis (DCNT). METODOLOGIA: Os participantes foram selecionados a partir de dados prévios do Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico para as estimativas sobre frequência e distribuição sociodemográfica de fatores de risco e proteção para doenças crônicas nas capitais dos 26 estados brasileiros e no Distrito Federal em 2006. RESULTADOS: Foram elegíveis 54.369 participantes sendo 51,5% classificados como inativos. Houve divergências importantes na graduação da AF pelas principais diretrizes entre os ativos (Kappa = 0,4). A frequência das sessões de AF foi o aspecto que mais contribuiu para a determinação do grau de AF. Recomendação que orienta a frequência diária resultou em uma prevalência menor de AF suficiente. As que orientam volume semanal, sem determinar frequência mínima tiveram as maiores prevalências de AF suficiente. Como decorrência dessa divergência, a prevalência de AF suficiente nas cidades abordadas variou, distinguindo diferentes rankings conforme a recomendação adotada. Cerca de 90% da população ativa realizava sessões com duração entre 30 a 60 minutos e não houve diferença significante entre o grupo que alcançou e o que não alcançou a meta da recomendação. A quase totalidade (90%) dos participantes que alcançou a meta se exercitava três ou mais vezes na semana e 80% dos que não alcançaram a meta se exercitavam entre 1 a 2 vezes na semana. A caminhada, o futebol e a musculação foram as modalidades de exercício físico ou esporte mais frequentes. Encontramos maior prevalência de AF em homens. Negros e amarelos foram fisicamente mais ativos, e a AF diminuiu com a idade, com menor escolaridade e com viuvez. Aproximadamente 65% da população consideraram a sua saúde boa ou excelente e entre os que a consideraram ruim, a maioria estava inativa. O deslocamento ativo e a dieta hipocalórica são características predominantes dos participantes ativos. O tabagismo foi mais frequente entre os inativos e o maior consumo de bebidas alcoólicas ocorreu entre os ativos. As pessoas fisicamente ativas mais frequentemente conheciam instalações próprias para a prática de AF nas proximidades de suas moradias. A inatividade física (62%) foi uma característica destacada entre os participantes portadores de DCNT. No conjunto 70% dos portadores de alguma DCNT não alcançaram a recomendação mínima de AF. CONCLUSÕES: O nível de AF variou muito entre as diretrizes que recomendam a AF. Para uma boa parte desta população, a resposta para a pergunta: \"estou fazendo AF suficiente para a minha saúde?\" Pode ser simultaneamente \"sim\" e \"não\", dependendo do critério da recomendação escolhida. Dentre os insuficientemente ativos, a duração do esforço em cada sessão foi adequada na maioria dos relatos, o que tornou a AF insuficiente foi a baixa frequência. Pensar estratégias que aumentem a frequência semanal para 2 a 3 dias pode elevar o nível de AF para 90% dos insuficientemente ativos
INTRODUCTION: In regards to the organization and implementation of physical activity (PA), there are many doubts related to the PA in adults residing in the capitals of the federation and in the Federal District. This study evaluated the prevalence of PA according to each of the main international guidelines that recommends the practice of PA for good health, explores its divergences, and also the concordances of the PA level classification. We also evaluated the association between the sociodemographic and behavioral characteristics to the practice of PA. More specifically, we focused on how the main components of the PA relates to themselves to determine the level of individual PA and which patterns are present in patients with chronic non-communicable diseases (CNCD). METHODOLOGY: Participants were selected from previous data that the System of Risk Factors Surveillance and Chronic Diseases Protection Telephone Survey, which was used for the estimation of frequency and sociodemographic distribution of risk and protective factors for chronic diseases in the 26 Brazilian state capitals and in the Federal District in 2006. RESULTS: There were 54,369 eligible participants of which 51.5% classified as inactive. There were important divergences in the PA graduation by the main guidelines among the active participants (Kappa = 0.4). The PA session frequency was the main reason that most contributed to the determination of the PA degree. The recommendation, which guides the daily frequency, resulted in the lowest prevalence of enough PA. The recommendations that guide weekly volume without determining minimum frequency had the highest prevalence of enough PA. As a result of this divergence, the prevalence of enough PA in the addressed cities ranged in different distinguishing rankings according to the adopted recommendation. About 90% of the active population performed sessions which lasted between 30 to 60 minutes. From this data, it was evident that there was no significant difference between the group which achieved the recommended PA and the the group which did not achieve the goal of the recommended PA level. Almost all of the participants (90%) who achieved the goal of recommended PA levels exercised three or more times a week and 80% of those who did not reach the goal exercised between 1 to 2 times a week. Trekking, soccer and weightlifting were the most frequent physical exercise modalities or sports performed. We found a higher prevalence of PA in men than in women. Furthermore, the study showed that Blacks and Yellows were more physically active. The amount PA level decreased with age, decreased amongst those with less education and amongst those who were widowed. Approximately 65% of the population considered their health good or excellent and among those who considered it bad, the majority were inactive. Active commuting and hypocaloric diets are predominant characteristics of the active participants. Smoking was more common among the inactive participants but higher alcohol consumption occurred among those that were active. Physically active people frequently knew more suitable facilities for the PA practice near their homes. Physical inactivity (62%) was a prominent characteristic among the participants suffering from CNCD. Overall, 70% of the participants suffering from any CNCD did not attain the minimum recommendations of PA. CONCLUSIONS: The PA levels varied widely among the guidelines that recommend PA. For a large portion of the population, the answer to the question of whether one is doing enough PA for ones health can simultaneously be \"yes\" and \"no\", depending on the criterion of the chosen recommendation. Among the insufficiently active population, the exercise duration in each session was adequate enough in most reports but what made the PA insufficient was the low frequency. Thinking about strategies to increase the weekly frequency for 2 to 3 days can raise the level of PA for 90% of the insufficiently active population
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Edeline, Jean-Marc. "Etude comparee des modifications des activites cellulaires dans la voie auditive et dans l'hippocampe au cours de l'acquisition et de la retention d'un apprentissage." Paris 6, 1988. http://www.theses.fr/1988PA066221.

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La multiplicite des structures du snc presentant des modifications lors d'un apprentissage pose le probleme de savoir ce que refletent ces changements. Cette question a amene les auteurs, dans leur premiere partie a enregistrer un temoin electro-physiologique dans un protocole ou l'acquisition sur un stimulus se fait en l'absence de rc comportementale et dans leur deuxieme partie a enregistrer les reponses sensorielles evoquees par le sc lors d'un conditionnement, son-choc
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Schmitt, Daniel. "Condicionantes para a aplicação da sanção administrativa de multa sobre o infrator pessoa física, no mercado de seguros privados fiscalizado pela SUSEP." Daniel Schmitt, 2016. http://hdl.handle.net/10438/18089.

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This paper deals with the repressive regime in the private insurance market ('MSP'), supervised by SUSEP – Superintendência de Seguros Privados. The research focus is to investigate the structure and the application of the norms that govern SUSEP's regulatory activity, regarding the application of the administrative sanction of fine on the individual offender. The administrative accountability in these cases is analyzed. For that, the theory of sanctioning is dealt with, dealing with the violation and the administrative sanction, especially the administrative penalty of fine. Some of the main principles of administrative sanctioning law are also highlighted, such as due process, lawfulness, characteristics and culpability. It also addresses the issue of relativisation of legality in special compliance regimes. These issues are displayed in an environment of sectoral regulation, therefore, contextualizing the sanctioning power of regulatory agencies. The repressive regime of the MSP is systematized. It identifies the National Council of Private Insurance (CNSP), the Resource Council of the National Private Insurance System (CRSNSP) and SUSEP. The normative archetype of the repressive regime of the MSP is presented, especially CNSP Resolution 243/11. A confrontation between SUSEP's guidelines and decisions of the CRSNSP in the opposite direction is made, regarding the imposition of the administrative penalty of fine on the individual offender, due to its administrative responsibility. At the end, as an outcome of the research, a set of constraints that ensure a more consistent application of the administrative penalty of fines on individuals - when considered as offenders in the MSP – is proposed.
O presente trabalho aborda o regime repressivo no mercado de seguros privados ('MSP'), fiscalizado pela Superintendência de Seguros Privados (SUSEP). O problema de pesquisa é investigar a estrutura e a aplicação das normas que regem a atividade regulatória da SUSEP, no que toca a aplicação da sanção administrativa de multa sobre o infrator pessoa física. Analisa-se a responsabilização administrativa realizada nestes casos. Para tanto, aborda-se a teoria da sanção, tratando do ilícito e da sanção administrativa, em especial da penalidade administrativa de multa. Alguns princípios informadores do direito administrativo sancionador também são destacados, tais como o devido processo legal, a legalidade, a tipicidade e a culpabilidade. Aborda-se, também, a questão da relativização da legalidade nos regimes de sujeição especial. Estas questões são expostas em um ambiente de regulação setorial, portanto, contextualizando-se o poder sancionador dos órgãos reguladores. É realizada a sistematização do regime repressivo do MSP. Identifica-se o Conselho Nacional de Seguros Privados (CNSP), o Conselho de Recursos do Sistema Nacional de Seguros Privados (CRSNSP) e a SUSEP. O arquétipo normativo do regime repressivo do MSP é descrito, destacando-se a Resolução CNSP no 243/11. Realiza-se um confronto entre orientações da SUSEP e decisões do CRSNSP em sentido contrário, a respeito da imposição da sanção administrativa de multa sobre o infrator pessoa física, em razão da sua responsabilização administrativa. Ao final, como resultado de pesquisa, propõe-se um conjunto de condicionantes que asseguram uma aplicação juridicamente mais consistente da penalidade administrativa de multa sobre as pessoas físicas, quando consideradas como infratores no MSP.
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Gilmartin, Marieke Rene. "Mapping learning networks by examining neuronal and population activity during trace classical fear conditioning." 2007. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-1811/index.html.

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(8787026), Ka H. Ng. "Increased Neural Activity in the Prefrontal Cortex During Fear Suppression to a Safety Signal." Thesis, 2020.

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Persistent and maladaptive fear in the absence of a threat can be disruptive because it decreases an organism’s opportunity to seek life-sustaining substances. Learned safety signaling can suppress fear and encourage reward-seeking behavior, thus freeing the organism from fear induced immobilization. The infralimbic (IL) region of the prefrontal cortex is important for recalling fear extinction memories and for suppressing fear via learned safety signals. Neurons in the IL show an excitatory response to an extinguished fear cue. We thus hypothesized that neurons in the IL would encode safety by showing an excitatory response during active fear suppression to a learned safety signal.

To assess global changes in IL activity, we monitored IL multi-unit activity to different cues while training animals in a fear-reward-safety discrimination task (Sangha, Chadick, & Janak, 2013). During the discrimination task, male rats learned that the reward cue predicted liquid sucrose, the fear cue predicted footshock and the joint presentation of both the fear and safety cues resulted in no footshock. We also counterbalanced the modality of fear and safety cues (auditory vs visual) with two separate groups of animals to control for potential sensory modality effects. Male rats showed high levels of freezing to the fear cue, and significantly reduced levels of freezing to the combined fear+safety cue. Male rats also showed high levels of port activity to the reward cue. There was no significant difference in the learning rate between the two counterbalanced conditions.

Our multi-unit-data showed an increase in IL neuronal firing to the fear+safety cue across training sessions. This effect was consistent between the two counterbalanced conditions. We also examined single-unit activity from all animals that received light as the safety cue (n=8). This allowed us to examine the population response profile with a subset of the total animals. Although not statistically significant, our preliminary single-unit data demonstrated a decrease in the percentage of neurons that showed an inhibitory response to the fear+safety cue, but no change in the percentage of neurons that showed an excitatory response to the fear+safety cue. There was also no change in the magnitude of averaged firing rate in fear+safety excitatory or inhibitory neurons across training. Taken together, the decreased inhibition of single-unit activity in the IL may drive the increased excitation in multi-unit activity in the IL during behavioral fear suppression to a safety signal.

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Books on the topic "Conditioning activity"

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L, Costill David, ed. Training for sport and activity: The physiological basis of the conditioning process. 3rd ed. Champaign, IL: Human Kinetics Publishers, 1993.

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J, Greene Gary, ed. Exercise for life: A physical activity guide forthe athletic and non-athletic retiree. Phoenix, Ariz: Health Plus Publishers, 1985.

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Florida, University Of. Conditioning: Health and Physical Activity Series. 2nd ed. Kendall/Hunt Publishing Company, 2006.

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Staff, University of Florida. Conditioning: Health and Physical Activity Series on Cd (Health and Physical Activity Series). Kendall/Hunt Publishing Company, 2005.

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Wilmore, Jack H. Training for sport and activity: The physiological basis of the conditioning process. 3rd ed. Allyn and Bacon, 1987.

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Costill, David L., and Jack H. Wilmore. Training for Sport and Activity The Physiological Basis of the Conditioning Process. Brown & Benchmark, 1988.

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Training for Sport and Activity: The Physiological Basis of the Conditioning Process. 3rd ed. William C Brown Pub, 1988.

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Dreshfield, Laura Jean. Hippocampal and behavioral activity during discrimination and reversal jaw movement conditioning in the rabbit. 1993.

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Gluckman, Sir Peter, Mark Hanson, Chong Yap Seng, and Anne Bardsley. Exercise and physical activity in pregnancy. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198722700.003.0029.

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Exercise has many beneficial effects for pregnant women and their offspring, reducing insulin resistance and blood pressure and supporting angiogenesis, while also helping to maintain a healthy weight and body composition. Exercise/physical activity also been reported to reduce the risks of large for gestational age/small for gestational age babies and of preterm birth. Moderate exercise of 30 minutes or more on most days is recommended. Reasonable goals of aerobic conditioning in pregnancy should be to maintain a good fitness level throughout pregnancy without trying to reach peak fitness level or train for athletic competition. However, extreme exercise in late gestation is cautioned against, as it is associated with lower birth weights and the possibility of long-term adverse consequences on the offspring.
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Borgnis, Ramie Lynn. Characterization of hippocampal single unit activity and unit/slow wave relations during classical conditioning in the rabbit. 1997.

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Book chapters on the topic "Conditioning activity"

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Lemos, José R., William B. Adams, Ilse Novak-Hofer, Jack A. Benson, and Irwin B. Levitan. "Regulation of Neuronal Activity by Protein Phosphorylation." In Neural Mechanisms of Conditioning, 397–420. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2115-6_28.

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Wolpe, Joseph. "The Two Models of Conditioning of Neurotic Anxiety." In Biological Psychiatry, Higher Nervous Activity, 849–54. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-8329-1_126.

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Corson, Samuel A., and Elizabeth O’Leary Corson. "Conditioning of Autonomic Functions, Schizokinesis, and Psychosomatic Medicine." In Biological Psychiatry, Higher Nervous Activity, 855–59. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-8329-1_127.

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Levey, Archie, Irene Martin, Robert Blizard, and Matthew Cobb. "Extinction Failure in Classical Conditioning as a Mechanism of Psychosomatic Illness." In Biological Psychiatry, Higher Nervous Activity, 871–77. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-8329-1_130.

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Pirch, James, Greg Rigdon, Hubert Rucker, and Kathy Turco. "Basal Forebrain Modulation of Cortical Cell Activity During Conditioning." In Advances in Experimental Medicine and Biology, 219–31. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4757-0145-6_11.

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Lennon, Nancy, and Freeman Miller. "Aerobic Conditioning and Walking Activity Assessment in Cerebral Palsy." In Cerebral Palsy, 1–12. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-50592-3_99-1.

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Lennon, Nancy, and Freeman Miller. "Aerobic Conditioning and Walking Activity Assessment in Cerebral Palsy." In Cerebral Palsy, 1401–12. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-74558-9_99.

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Maltzman, I., and M. Pendery. "An Interpretation of Human Classical Conditioning of Electrodermal Activity." In Neurophysiology and Psychophysiology, 333–44. London: Routledge, 2021. http://dx.doi.org/10.4324/9781003164647-35.

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Baranyi, Attila, and Magdolna B. Szente. "Postsynaptic Activity-Dependent Facilitation of Excitatory Synaptic Transmission in the Neocortex." In Cellular Mechanisms of Conditioning and Behavioral Plasticity, 391–402. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4757-9610-0_36.

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Wilson, F. A. W., M. W. Brown, and I. P. Riches. "Neuronal Activity in the Inferomedial Temporal Cortex Compared with That in the Hippocampal Formation." In Cellular Mechanisms of Conditioning and Behavioral Plasticity, 313–28. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4757-9610-0_30.

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Conference papers on the topic "Conditioning activity"

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Berman, Ega Taqwali, Budi Mulyanti, Ida Hamidah, and Agus Setiawan. "Factor Analysis of Supporting Air Conditioning Practicum Activity in Vocational Education." In 5th Asian Education Symposium 2020 (AES 2020). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/assehr.k.210715.087.

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Faghih, Rose T., Patrick A. Stokes, Marie-France Marin, Rachel G. Zsido, Sam Zorowitz, Blake L. Rosenbaum, Huijin Song, et al. "Characterization of fear conditioning and fear extinction by analysis of electrodermal activity." In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7320204.

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Budiman, Fajar, Muhammad Rivai, I. Gusti Bagus Prasta Raditya, Daniel Krisrenanto, and Irma Zahroul Amiroh. "Smart Control of Air Conditioning System Based on Number and Activity Level of Persons." In 2018 International Seminar on Intelligent Technology and Its Applications (ISITIA). IEEE, 2018. http://dx.doi.org/10.1109/isitia.2018.8711311.

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Lippolis, G., E. Petagna, G. Ragazzo, and P. Tortorelli. "Melt Treatment for Conditioning of Drums Produced During Soil Reclamation of Low Activity Trenches." In ASME 2003 9th International Conference on Radioactive Waste Management and Environmental Remediation. ASMEDC, 2003. http://dx.doi.org/10.1115/icem2003-5005.

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In the past years, many studies had been carried out in the ITREC Plant, located in ENEA – Trisaia Research Centre, in the field of nuclear fuel reprocessing and with re-fabrication techniques to the Th-233U cycle as an alternative to the U-Pu cycle. During these activities low level solid wastes were produced, containerised, stored into trenches and progressively covered with earth. In the 1980’s the trenches were reclaimed obtaining 3000 drums (200 liter volume) of solid LLW and about 6000 drums of low contaminated soil. In this presentation are described the action of reclamation of the trenches, sealing the low contaminated soil, and the melting campaign of contaminated drums.
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Sarmento, H., M. Peralta, and A. Marques. "13 Multimorbidity and physical activity recommendations in european older adults." In International Sports Science + Sports Medicine Conference 2017 ABSTRACTS, Incorporating Sports Physiotherapy and Strength & Conditioning, Newcastle Upon Tyne, England 5–7th September 2017. BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine, 2017. http://dx.doi.org/10.1136/bjsports-2017-098966.17.

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Hamad, Eyad M., Samer I. Al-Gharabli, Munib M. Saket, and Omar Jubran. "A Brain Machine Interface for command based control of a wheelchair using conditioning of oscillatory brain activity." In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2017. http://dx.doi.org/10.1109/embc.2017.8036995.

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Leeuwis, Nikki, Maryam Alimardani, and Tom Van Bommel. "'Neuromarketing as a tool for environmental conditioning and sustainable consumption." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001823.

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The impact of human factors on climate change is unequivocal. While consumers are increasingly becoming aware of their environmental footprint, this is not sufficient: contextual factors such as pricing, convenience, and packaging play a role in consumers’ decision-making. This has created a gap between consumers’ attitudes and behavior, which calls for intervention of behavioral sciences to change consumer behavior and consequently combat the climate crisis effectively. Consumer neuroscience methodology has been proposed as a potential tool to untangle the neural and psychological origins of consumers’ behavior since subjective reports may be biased by social desirability and therefore are not a reliable measure of pro-environmental behavior. Prior studies have shown that conditioning the consumer with information on the environmental impact of products can influence their buying behavior and brain activity. This paper provides an extended exploration of past works on consumer neuroscience, environmental behavior, and conditioning techniques. We aim to unite the current theories and common practices and uncover future research directions in an effort to develop a neuroscientifically supported conditioning intervention that could promote pro-environmental behavior in consumers.
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Karlina, Olga K., Galina A. Varlakova, Sergei A. Dmitriev, Michael I. Ojovan, Valery V. Poluektov, and Vladislav A. Petrov. "Thermochemical Conditioning of Radioactive Waste: Structure and Properties of Final Processed Product." In ASME 2003 9th International Conference on Radioactive Waste Management and Environmental Remediation. ASMEDC, 2003. http://dx.doi.org/10.1115/icem2003-4560.

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Thermochemical processing method is based on utilization of energy of chemical reactions between components of special exothermic mixtures (termed heat base) to melt radioactive waste and form a vitreous melt after cooling of which a durable monolith product is formed in which radionuclides are fixed. Compositions were studied, structure and properties of final products of thermochemical treatment of ash residue from incineration of solid radioactive waste, spent inorganic ion exchangers (e.g. clinoptililite and silica gel), contaminated clay and sand-based soils, Investigations showed that matrix material is dominantly amorphous and on compliesis to basic requirements to solidified radioactive wast of medium level of activity.
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Deneanu, Nicoleta, Magdalena Dianu, and Ion Teoreanu. "Packaging and Conditioning of Solvent Wastes From Decontamination Operation Cernavoda NPP." In ASME 2003 9th International Conference on Radioactive Waste Management and Environmental Remediation. ASMEDC, 2003. http://dx.doi.org/10.1115/icem2003-4759.

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Solvent wastes produced at Cernavoda NPP consist of miscellaneous acetone, toluene, methanol, chloroform, triclorethan, white spirit and ethylene glycol. These are normally LLW containing only relatively small quantities of beta/gamma emitting radionuclides and varying amounts of tritium with activity below E08Bq/l. This paper is a review of some current innovative work of Waste Management Facility from Institute for Nuclear Research Pitesti in the development of a viable solidification technology to convert solvent wastes into a stable monolithic form, which minimises the probability to release tritium in the environment during interim storage, transportation and final disposal. The paper presents the author’s research on immobilisation of solvent wastes by cementation using aluminium stearate additive. A quality assurance program should accompany the production of waste forms. The goal of all tests should be to obtain a license for a certain process from a competent authority. The process will be clean, which means there will be no secondary waste and low doses to the personnel will be achieved; the product quality will meet any National requirement and the reproducibility of the process meets any QA requirement.
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Deneanu, Nicoleta T., Ion V. Popescu, Mirela F. Dulama, and Elena I. Baboescu. "Packaging and Conditioning of Radioactive Oil Wastes From Cernavoda NPP Operation." In ASME 2001 8th International Conference on Radioactive Waste Management and Environmental Remediation. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/icem2001-1314.

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Abstract Radioactive oil wastes produced at Cernavoda NPP consist of lubricating oils from primary heat transport pumps, hydraulic fluids from fuelling machines and turbine oils. These are normally LLW containing only relatively small quantities of beta/gamma-emitting radionuclides. The main contamination pathway is the contact with the reactor primary coolant. The waste contains varying amounts of tritium with activity below 108Bq/1. The objective of solidification is to convert radioactive waste into a stable monolithic form, which minimizes the probability to release tritium in the environment during interim storage, transportation and final disposal. The solidified waste that leaves the Waste Management facility from INR Pitesti should be of such chemical, mechanical, thermal and radiolytic stability as to assure its integrity over the time required for the decay of the contained radionuclides to an acceptable level. Laboratory studies concerning the cementation of radioactive oil waste have been undertaken at the Institute for Nuclear Research Pitesti. A quality assurance program should accompany the production of waste forms. The goal of all tests should be to obtain a license for a certain process from a competent authority. Criteria that might be applied in the selection of treatment process and of waste storage and/or disposal are the complexity of volume reduction, the complexity of the technology and equipment, the level of process development, and the regulatory requirements.
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Reports on the topic "Conditioning activity"

1

Patil, Bhimanagouda S., Ron Porat, G. K. Jayaprakasha, and K. N. C. Murthy. Optimization of Postharvest Storage Conditions to Maintain Fruit Quality and Health Maintaining Properties of Grapefruit. United States Department of Agriculture, January 2010. http://dx.doi.org/10.32747/2010.7613879.bard.

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Antioxidant activity of fruits is gaining wide interest among consumers due to its importance in counteracting oxidative stress, free radicals and preventing DNA damage. Oxygen radical absorbance capacity (ORAC) assay is one of the commonly used assays to measure the antioxidant activity, which is based on hydrogen atom transfer mechanism. Furocoumarins present in grapefruit are reported to have antiproliferative activity, induce GST activity, inhibit biofilm formation and increase bioavailability of drugs. In the present project ORAC values were measured of Star Ruby grapefruit undergone ethylene degreening treatment, cold storage and temperature conditioning treatment, and modified atmosphere packaging which were stored at different temperatures for prolonged period. In addition, furocoumarins were quantified in Star Ruby grapefruits from cold storage and conditioning experiment conducted in Israel. Conditioning treatment is practiced prior cold storage to reduce chilling injury in grapefruits during cold storage for prolonged period. Levels of 6,7-dihyrdoxy bergamottin decreased during storage period in all three treatments.
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2

Yahav, Shlomo, John McMurtry, and Isaac Plavnik. Thermotolerance Acquisition in Broiler Chickens by Temperature Conditioning Early in Life. United States Department of Agriculture, 1998. http://dx.doi.org/10.32747/1998.7580676.bard.

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The research on thermotolerance acquisition in broiler chickens by temperature conditioning early in life was focused on the following objectives: a. To determine the optimal timing and temperature for inducing the thermotolerance, conditioning processes and to define its duration during the first week of life in the broiler chick. b. To investigate the response of skeletal muscle tissue and the gastrointestinal tract to thermal conditioning. This objective was added during the research, to understand the mechanisms related to compensatory growth. c. To evaluate the effect of early thermo conditioning on thermoregulation (heat production and heat dissipation) during 3 phases: (1) conditioning, (2) compensatory growth, (3) heat challenge. d. To investigate how induction of improved thermotolerance impacts on metabolic fuel and the hormones regulating growth and metabolism. Recent decades have seen significant development in the genetic selection of the meat-type fowl (i.e., broiler chickens); leading to rapid growth and increased feed efficiency, providing the poultry industry with heavy chickens in relatively short growth periods. Such development necessitates parallel increases in the size of visceral systems such as the cardiovascular and the respiratory ones. However, inferior development of such major systems has led to a relatively low capability to balance energy expenditure under extreme conditions. Thus, acute exposure of chickens to extreme conditions (i.e., heat spells) has resulted in major economic losses. Birds are homeotherms, and as such, they are able to maintain their body temperature within a narrow range. To sustain thermal tolerance and avoid the deleterious consequences of thermal stresses, a direct response is elicited: the rapid thermal shock response - thermal conditioning. This technique of temperature conditioning takes advantage of the immaturity of the temperature regulation mechanism in young chicks during their first week of life. Development of this mechanism involves sympathetic neural activity, integration of thermal infom1ation in the hypothalamus, and buildup of the body-to-brain temperature difference, so that the potential for thermotolerance can be incorporated into the developing thermoregulation mechanisms. Thermal conditioning is a unique management tool, which most likely involves hypothalamic them1oregulatory threshold changes that enable chickens, within certain limits, to cope with acute exposure to unexpected hot spells. Short-tem1 exposure to heat stress during the first week of life (37.5+1°C; 70-80% rh; for 24 h at 3 days of age) resulted in growth retardation followed immediately by compensatory growth" which resulted in complete compensation for the loss of weight gain, so that the conditioned chickens achieved higher body weight than that of the controls at 42 days of age. The compensatory growth was partially explained by its dramatic positive effect on the proliferation of muscle satellite cells which are necessary for further muscle hypertrophy. By its significant effect of the morphology and functioning of the gastrointestinal tract during and after using thermal conditioning. The significant effect of thermal conditioning on the chicken thermoregulation was found to be associated with a reduction in heat production and evaporative heat loss, and with an increase in sensible heat loss. It was further accompanied by changes in hormones regulating growth and metabolism These physiological responses may result from possible alterations in PO/AH gene expression patterns (14-3-3e), suggesting a more efficient mechanism to cope with heat stress. Understanding the physiological mechanisms behind thermal conditioning step us forward to elucidate the molecular mechanism behind the PO/AH response, and response of other major organs. The thermal conditioning technique is used now in many countries including Israel, South Korea, Australia, France" Ecuador, China and some places in the USA. The improvement in growth perfom1ance (50-190 g/chicken) and thermotolerance as a result of postnatal thermal conditioning, may initiate a dramatic improvement in the economy of broiler's production.
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3

Díaz de Astarloa, Bernardo, and Ezequiel Tacsir. Cluster Initiatives and Economic Resilience: Evidence from a Technology Cluster in Argentina. Inter-American Development Bank, December 2022. http://dx.doi.org/10.18235/0004594.

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In this paper, we study the role of a cluster initiative in fostering economic resilience among firms in a local technology cluster in Argentina. We focus on two aggregate shocks that hit the Argentine economy, including first wave of the COVID-19 pandemic. Our analysis is based on interviews with authorities and members of the cluster initiative, local firms, and policy makers, as well as on firm-level administrative tax records. We find that the cluster organization provides members with resources that could foster resilience, including access to specialized human capital, information on business opportunities, and assistance in applying for government support programs. However, while members of the cluster organization appear to be more resilient than non-members, even within the same regional cluster, after conditioning on firm characteristics we find little evidence of a positive association between belonging to the cluster organization and economic resilience. Members of the cluster organization are neither less likely to exit nor adapt by switching their main economic activity and did not show statistically significantly higher revenue growth than nonmembers. Member firms do appear to have been more able than non-members to keep up with tax obligations during the first wave of the COVID-19 pandemic.
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4

Porat, Ron, Gregory T. McCollum, Amnon Lers, and Charles L. Guy. Identification and characterization of genes involved in the acquisition of chilling tolerance in citrus fruit. United States Department of Agriculture, December 2007. http://dx.doi.org/10.32747/2007.7587727.bard.

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Citrus, like many other tropical and subtropical fruit are sensitive to chilling temperatures. However, application of a pre-storage temperature conditioning (CD) treatment at 16°C for 7 d or of a hot water brushing (HWB) treatment at 60°C for 20 sec remarkably enhances chilling tolerance and reduces the development of chilling injuries (CI) upon storage at 5°C. In the current research, we proposed to identify and characterize grapefruit genes that are induced by CD, and may contribute to the acquisition of fruit chilling tolerance, by two different molecular approaches: cDNA array analysis and PCR cDNA subtraction. In addition, following the recent development and commercialization of the new Affymetrix Citrus Genome Array, we further performed genome-wide transcript profiling analysis following exposure to CD and chilling treatments. To conduct the cDNA array analysis, we constructed cDNA libraries from the peel tissue of CD- and HWB-treated grapefruit, and performed an EST sequencing project including sequencing of 3,456 cDNAs from each library. Based on the obtained sequence information, we chose 70 stress-responsive and chilling-related genes and spotted them on nylon membranes. Following hybridization the constructed cDNA arrays with RNA probes from control and CD-treated fruit and detailed confirmations by RT-PCR analysis, we found that six genes: lipid-transfer protein, metallothionein-like protein, catalase, GTP-binding protein, Lea5, and stress-responsive zinc finger protein, showed higher transcript levels in flavedo of conditioned than in non-conditioned fruit stored at 5 ᵒC. The transcript levels of another four genes: galactinol synthase, ACC oxidase, temperature-induced lipocalin, and chilling-inducible oxygenase, increased only in control untreated fruit but not in chilling-tolerant CD-treated fruit. By PCR cDNA subtraction analysis we identified 17 new chilling-responsive and HWB- and CD-induced genes. Overall, characterization of the expression patterns of these genes as well as of 11 more stress-related genes by RNA gel blot hybridizations revealed that the HWB treatment activated mainly the expression of stress-related genes(HSP19-I, HSP19-II, dehydrin, universal stress protein, EIN2, 1,3;4-β-D-glucanase, and SOD), whereas the CD treatment activated mainly the expression of lipid modification enzymes, including fatty acid disaturase2 (FAD2) and lipid transfer protein (LTP). Genome wide transcriptional profiling analysis using the newly developed Affymetrix Citrus GeneChip® microarray (including 30,171 citrus probe sets) revealed the identification of three different chilling-related regulons: 1,345 probe sets were significantly affected by chilling in both control and CD-treated fruits (chilling-response regulon), 509 probe sets were unique to the CD-treated fruits (chilling tolerance regulon), and 417 probe sets were unique to the chilling-sensitive control fruits (chilling stress regulon). Overall, exposure to chilling led to expression governed arrest of general cellular metabolic activity, including concretive down-regulation of cell wall, pathogen defense, photosynthesis, respiration, and protein, nucleic acid and secondary metabolism. On the other hand, chilling enhanced various adaptation processes, such as changes in the expression levels of transcripts related to membranes, lipid, sterol and carbohydrate metabolism, stress stimuli, hormone biosynthesis, and modifications in DNA binding and transcription factors.
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5

Meiri, Noam, Michael D. Denbow, and Cynthia J. Denbow. Epigenetic Adaptation: The Regulatory Mechanisms of Hypothalamic Plasticity that Determine Stress-Response Set Point. United States Department of Agriculture, November 2013. http://dx.doi.org/10.32747/2013.7593396.bard.

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Our hypothesis was that postnatal stress exposure or sensory input alters brain activity, which induces acetylation and/or methylation on lysine residues of histone 3 and alters methylation levels in the promoter regions of stress-related genes, ultimately resulting in long-lasting changes in the stress-response set point. Therefore, the objectives of the proposal were: 1. To identify the levels of total histone 3 acetylation and different levels of methylation on lysine 9 and/or 14 during both heat and feed stress and challenge. 2. To evaluate the methylation and acetylation levels of histone 3 lysine 9 and/or 14 at the Bdnfpromoter during both heat and feed stress and challenge. 3. To evaluate the levels of the relevant methyltransferases and transmethylases during infliction of stress. 4. To identify the specific localization of the cells which respond to both specific histone modification and the enzyme involved by applying each of the stressors in the hypothalamus. 5. To evaluate the physiological effects of antisense knockdown of Ezh2 on the stress responses. 6. To measure the level of CpG methylation in the promoter region of BDNF in thermal treatments and free-fed, 12-hour fasted, and re-fed chicks during post-natal day 3, which is the critical period for feed-control establishment, and 10 days later to evaluate longterm effects. 7. The phenotypic effect of antisense “knock down” of the transmethylaseDNMT 3a. Background: The growing demand for improvements in poultry production requires an understanding of the mechanisms governing stress responses. Two of the major stressors affecting animal welfare and hence, the poultry industry in both the U.S. and Israel, are feed intake and thermal responses. Recently, it has been shown that the regulation of energy intake and expenditure, including feed intake and thermal regulation, resides in the hypothalamus and develops during a critical post-hatch period. However, little is known about the regulatory steps involved. The hypothesis to be tested in this proposal is that epigenetic changes in the hypothalamus during post-hatch early development determine the stress-response set point for both feed and thermal stressors. The ambitious goals that were set for this proposal were met. It was established that both stressors i.e. feed and thermal stress, can be manipulated during the critical period of development at day 3 to induce resilience to stress later in life. Specifically it was established that unfavorable nutritional conditions during early developmental periods or heat exposure influences subsequent adaptability to those same stressful conditions. Furthermore it was demonstrated that epigenetic marks on the promoter of genes involved in stress memory are altered both during stress, and as a result, later in life. Specifically it was demonstrated that fasting and heat had an effect on methylation and acetylation of histone 3 at various lysine residues in the hypothalamus during exposure to stress on day 3 and during stress challenge on day 10. Furthermore, the enzymes that perform these modifications are altered both during stress conditioning and challenge. Finally, these modifications are both necessary and sufficient, since antisense "knockdown" of these enzymes affects histone modifications, and as a consequence stress resilience. DNA methylation was also demonstrated at the promoters of genes involved in heat stress regulation and long-term resilience. It should be noted that the only goal that we did not meet because of technical reasons was No. 7. In conclusion: The outcome of this research may provide information for the improvement of stress responses in high yield poultry breeds using epigenetic adaptation approaches during critical periods in the course of early development in order to improve animal welfare even under suboptimum environmental conditions.
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