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Journal articles on the topic 'Congenital malaria'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Gopikrishnan, Kalathil Gopalakrishna Pillai, Kalaivanan Naveen Chandher, and Selvakumar Jagadeeswari. "CONGENITAL MALARIA IN A NEONATE." Gomal Journal of Medical Sciences 19, no. 4 (2021): 161–62. http://dx.doi.org/10.46903/gjms/19.04.1031.

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Congenital malaria isn’t common even though malaria is endemic in India. Here, we will be reporting about a neonate of age seven days with splenomegaly and fever diagnosed as congenital malaria. On smear study it was found to have malarial parasite incidentally. In a case of neonatal sepsis congenital malaria can be suspected. Early diagnosis and treatment is thus important in preventing neonatal mortality.

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2

Kuyucu, Necdet, Neşe Yaralı, Gülşen Sörımezışık, Sümer Yılmaz, and Tahsin Teziç. "Congenital malaria: a case report." Turkish Journal of Pediatrics 41, no. 1 (1999): 103–6. http://dx.doi.org/10.24953/turkjpediatr.1999.3205.

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Congenital malaria is an uncommon disease even in endemic areas. A 19-day-old female infant with congenital malaria is presented. The mother of the patient was diagnosed to have malaria at the seventh month of gestation and was treated with chloroquine orally for three days. No malarial prophylaxis was given. The infant developed fever, hyperbilirubinemia, anemia and hepatosplenomegaly postnatally. Thin blood smears revealed many Plasmodium vivax parasites. She was treated with oral chloroquine for three days. We emphasize the importance of adequate antenatal medical therapy and prophylaxis du

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3

Joffe, Ari, and Taj Jadavji. "CONGENITAL MALARIA." Pediatric Infectious Disease Journal 9, no. 7 (1990): 522. http://dx.doi.org/10.1097/00006454-199007000-00016.

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4

Thapar, RK, A. Saxena, and A. Devgan. "Congenital Malaria." Medical Journal Armed Forces India 64, no. 2 (2008): 185–86. http://dx.doi.org/10.1016/s0377-1237(08)80079-2.

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5

Dianto, Dianto, and T. H. Rampengan. "Congenital Falciparum Malaria with Chloroquine Resistance Type ll." Paediatrica Indonesiana 29, no. 11-12 (2018): 237–40. http://dx.doi.org/10.14238/pi29.11-12.1989.237-40.

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A case of congenial falciparum malaria has been reported. The diagnosis was based ·on history of illness, clinical manifestations, age of the child and presence of the ring form falciparum malaria in the peripheral blood films. Treatment with chloroquine showed resistance type II, though treatment with quinine was successful.  In malaria endemic areas, although rare, one must be aware of the possibility of congenital malaria.

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Das, Joydeep, and Saugata Choudhury. "Case series on congenital malaria from a tertiary care hospital in North Eastern India." Asian Journal of Medical Sciences 12, no. 9 (2021): 166–68. http://dx.doi.org/10.3126/ajms.v12i9.37273.

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Malaria in early life is due to transfer of parasitized maternal red blood cell across placenta or direct transfer of parasite from placental syncytotrophoblast. Congenital malaria is defined as malaria acquired from mother in prenatal or perinatal period. Most of the cases in endemic area, passive transfer of high amount of maternal IgG antibody binds to malarial antigen and various components of parasites giving rise to various atypical clinical presentation. This case series will help neonatologist to think malaria in all non-specific symptoms of inconsolable cry, poor feeding, lethargy, ev

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7

Bhatia, Ravi, Dinesh Rajwaniya, and Priti Agrawal. "Congenital Malaria due to Plasmodium Vivax Infection in a Neonate." Case Reports in Pediatrics 2016 (2016): 1–2. http://dx.doi.org/10.1155/2016/1929046.

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Although malaria is endemic in India, congenital malaria is not very common. Congenital malaria is a very rare condition in both endemic and nonendemic areas. We report a case of congenital malaria in a six-day-old neonate with fever and splenomegaly. The diagnosis was picked up accidentally on a peripheral smear examination. Congenital malaria should be kept as differential diagnosis of neonatal sepsis. Timely detection of this condition could lead to early diagnosis and treatment, thereby preventing neonatal mortality.

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8

Singh, Avinish, Kriti Mohan, Balram Ji Omar, et al. "Congenital Malaria in Newborns Delivered to Malaria-infected Mothers in the Hilly Region of Northern India: Is it Deadly?" Current Pediatric Reviews 18, no. 1 (2022): 53–58. http://dx.doi.org/10.2174/1573396317666211102093324.

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Background: Malaria is endemic in many states of India. Though there are reports of maternal and congenital malaria from endemic areas, however, there remains a paucity of data from hilly terrains. The present study evaluated the prevalence, clinical and microbiological spectrum of maternal and congenital malaria at a tertiary health care facility in Northern India over a period of 18 months. Methods: In this observational study, mothers along with their newborns were evaluated for malaria by maternal, placental, and cord blood smear examination and rapid point-of-care diagnostic serological t

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9

Omer, Samia A., Ishag Adam, Ali Noureldien, et al. "Congenital Malaria in Newborns Delivered to Mothers with Malaria-Infected Placenta in Blue Nile State, Sudan." Journal of Tropical Pediatrics 66, no. 4 (2020): 428–34. http://dx.doi.org/10.1093/tropej/fmz083.

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Abstract Diagnosis of congenital malaria is complicated by the low density of the parasite circulating in the cord blood and/or the peripheral blood of the newborns. Molecular techniques are significantly more sensitive than blood smears in detecting low-level parasitemia. This study investigated the prevalence of congenital malaria by the use of the real-time polymerase chain reaction (real-time PCR) in 102 babies born to mothers with microscopically confirmed infected placenta from Blue Nile state, Sudan. At delivery time, placental, maternal peripheral and cord blood samples in addition to

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10

S, Sri Wahyunie, Nurhayana Sennang, D. Daud, and Mansyur Arif. "MALARIA KONGENITAL." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 21, no. 2 (2018): 202. http://dx.doi.org/10.24293/ijcpml.v21i2.1109.

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Congenital Malaria is an infectious disease caused by the malaria parasite that is transmitted from mother to child through theplacenta during pregnancy or at delivery. Clinical manifestations which may arise due to Plasmodium infection are: the irritability,fever, anaemia, jaundice and hepatosplenomegaly. The incidence of congenital malaria according to the National Basic Health Research2010 is only about 0.3%. Forty two days old male baby with the main complaints fever and pale since he was three (3) weeks old. Fromthe physical examination the reviewer found anaemia, jaundice and splenomegal

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11

Eki-udoko, Fidelis E., Ayebo Sadoh, Michael O. Ibadin, and Augustine I. Omoigberale. "Placental Malaria histological features and the burden of congenital malaria among HIV/ malaria co-infected mothers in Benin City, Edo State." Nigerian Journal of Paediatrics 48, no. 1 (2021): 12–19. http://dx.doi.org/10.4314/njp.v48i1.3.

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Background: It is well documented that sub-Saharan Africa bears the highest burden of both malaria and HIV. Coinfection with both diseases is also well documented. Malaria parasites infecting the placenta lead to inflammation, intervillous fibrin deposition and infarction. This pathologic effect of malaria on the placental has led to the staging of placental malaria histology. These pathologic features may reflect different levels in the breach of the integrity of the placenta which may predispose to transmission of congenital malaria and possibly HIV. But few if any have examined the associat

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12

Hassan, Mahmuda, Marium Begum, AW Shamsur Rob, Ashruf Uddin Ahmed, and Taslim Uddin Ahmed. "Congenital Malaria in Neonate." Bangladesh Journal of Child Health 37, no. 2 (2013): 133–35. http://dx.doi.org/10.3329/bjch.v37i2.17272.

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13

Ørbeck, Harald, and Eivind Ragnhildstveit. "Congenital Malaria in Scandinavia." Scandinavian Journal of Infectious Diseases 18, no. 1 (1986): 79–81. http://dx.doi.org/10.3109/00365548609032310.

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14

M. K, Arun, and Veena K. R. "PREVALANCE OF CONGENITAL MALARIA." Journal of Evolution of Medical and Dental Sciences 3, no. 61 (2014): 13557–59. http://dx.doi.org/10.14260/jemds/2014/3809.

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15

Tao, Zhi-yong, Qiang Fang, Xue Liu, et al. "Congenital Malaria in China." PLoS Neglected Tropical Diseases 8, no. 3 (2014): e2622. http://dx.doi.org/10.1371/journal.pntd.0002622.

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16

Pengsaa, Krisana. "Congenital malaria in Thailand." Annals of Tropical Paediatrics 27, no. 2 (2007): 133–39. http://dx.doi.org/10.1179/146532807x192507.

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17

Otuli Noël, Labama, Bosenge Nguma Jean-Didier, Maindo Alongo Mike-Antoine, et al. "Prevalence of Congenital Malaria in Kisangani, A Stable Malaria Transmission Area in Democratic Republic of the Congo." Infectious Diseases in Obstetrics and Gynecology 2020 (February 25, 2020): 1–7. http://dx.doi.org/10.1155/2020/2176140.

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Background. Gestational malaria is a major public health problem. It produces fetal complications such as low birth weight, perinatal mortality, and congenital malaria. The present study is aimed at determining the prevalence of congenital malaria and its neonatal complications in the city of Kisangani. Methods. We conducted a cross-sectional study in Kisangani from 1 January to 30 September 2018. Our study population was composed of 1248 newborns born in our study sites, during the period of our study. Just after their birth, we performed the thick drop smear in the placental print and in umb

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18

Tahirou, I., M. O. Zara, M. L. Moustapha, et al. "Congenital Malaria and Its Associated Factors at Issaka Gazobi Maternity of Niamey in Niger." International Journal of Pediatrics 2020 (October 17, 2020): 1–6. http://dx.doi.org/10.1155/2020/7802560.

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Background. Congenital malaria is a serious and common infection in tropical Africa. It has multiple consequences on the newborn and the mother. Objective. The objective of this study is to calculate the prevalence of congenital malaria, describe its clinical signs, and analyze its associated factors. Methodology. It is a cross-sectional and prospective study, conducted at Issaka Gazobi Maternity of Niamey, from June 1 to November 30, 2017. The diagnosis was made by microscopy of a thick and thin blood smear of mother, newborn, and umbilical cord. Results. Two hundred and forty-nine (249) cons

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19

Felix Fiavor and Chukwuma Chinaza Adaobi. "Review on the prevention of malaria among pregnant women attending antenatal clinic." GSC Advanced Research and Reviews 11, no. 3 (2022): 135–40. http://dx.doi.org/10.30574/gscarr.2022.11.3.0149.

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The study visualizes the Prevention of Malaria among Pregnant Women Attending Antenatal Clinic. Malaria in pregnancy has been identified as a global health challenge because of the life-threatening complications it poses to both the mother and the unborn child. These complications include maternal anemia, premature delivery, low birth weight, miscarriage, congenital infection and perinatal mortality. Five different malaria parasite species cause malaria infection: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium knowlesi. The increasing rate of mala

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20

Felix, Fiavor, and Chinaza Adaobi Chukwuma. "Review on the prevention of malaria among pregnant women attending antenatal clinic." GSC Advanced Research and Reviews 11, no. 3 (2022): 135–40. https://doi.org/10.5281/zenodo.6817388.

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The study visualizes the Prevention of Malaria among Pregnant Women Attending Antenatal Clinic. Malaria in pregnancy has been identified as a global health challenge because of the life-threatening complications it poses to both the mother and the unborn child. These complications include maternal anemia, premature delivery, low birth weight, miscarriage, congenital infection and perinatal mortality. Five different malaria parasite species cause malaria infection: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium knowlesi. The increasing rate of mala

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21

Etefia, Etefia Uwem. "The Prevalence of Congenital Malaria." International Annals of Science 8, no. 1 (2019): 22–29. http://dx.doi.org/10.21467/ias.8.1.22-29.

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This study was aimed at highlighting on the prevalence of malaria among pregnant women in Nigeria within the last ten years. The prevalence of congenital malaria in Nigeria varies and it affects every geopolitical zone in Nigeria. This is because Nigeria like other countries in the tropics and subtropics has factors which favour the survival of mosquito. Although the World Health Organization (WHO) recommends the use of insecticide treated nets and effective case management of uncomplicated malaria as a feasible and cost-effective control strategy, Nigeria remains one of the worst affected cou

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22

Shedrack, Egbunu Akor, Achimugu Musa Dickson, SPO Akogu, et al. "Biochemical and Haematological Changes Associated with Transplacental Congenital Malaria in Kogi State, North-Central Nigeria." Journal of Medical Laboratory Science 31, no. 3 (2021): 1–10. https://doi.org/10.5281/zenodo.5546377.

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<strong>ABSTRACT</strong> <strong>Background:</strong> Transplacental congenital malaria is a vertical transplacental transmission of malaria parasites from the mother to the baby in utero or perinatally during labor. Cord blood that conveys oxygen and nutrients from mother to fetus and return with carbon dioxide and other waste materials can transmit malaria pathogen. This study aims to establish early diagnosis of transplacental congenital malaria using cord blood biochemical and haematological indices. <strong>Methods</strong>: Cord blood from 164 babies delivered at three hospitals in Kogi

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23

Airede, Abdulkareem I. "Congenital malaria with chloroquine resistance." Annals of Tropical Paediatrics 11, no. 3 (1991): 267–69. http://dx.doi.org/10.1080/02724936.1991.11747512.

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24

Brabin, Bernard J. "Congenital malaria—a recurrent problem." Annals of Tropical Paediatrics 27, no. 2 (2007): 95–98. http://dx.doi.org/10.1179/146532807x192453.

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25

Fischer, Philip R. "Congenital Malaria: An African Survey." Clinical Pediatrics 36, no. 7 (1997): 411–13. http://dx.doi.org/10.1177/000992289703600706.

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26

Viraraghavan, Roopa, and Barbara Jantausch. "Congenital Malaria: Diagnosis and Therapy." Clinical Pediatrics 39, no. 1 (2000): 66–67. http://dx.doi.org/10.1177/000992280003900117.

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27

Okperi, Blessing O. "Congenital Malaria in Warri, Nigeria." Biosciences Biotechnology Research Asia 8, no. 2 (2011): 615–16. http://dx.doi.org/10.13005/bbra/909.

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28

Mudji, Junior E., Johannes Blum, Timothy D. Rice, and Frederick N. Baliraine. "Congenital malaria and neonatal bacterial co-infection in twins prematurely born to a mother with sickle-cell anaemia in the Democratic Republic of the Congo." MalariaWorld Journal 8, no. 14 (2017): 1–3. https://doi.org/10.5281/zenodo.10777282.

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<strong>Background.</strong> We report cases of gestational and congenital malaria with twin prematurity, low birth weight and bacterial coinfection. Congenital malaria is often misdiagnosed for lack of specific symptoms and a general lack of awareness of this presumably uncommon condition, and its diagnosis and prognosis become even more complex in the event of bacterial coinfections. <strong>Case presentation.</strong> A 35-weeks pregnant woman with sickle-cell disease and a history of spontaneous abortions was admitted at Vanga Hospital in DR Congo. She had fever (38.9°C) and microscopy

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29

Kajoba, Dickson, Walufu Ivan Egesa, Habonimana Jean Petit, et al. "Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review." Case Reports in Infectious Diseases 2021 (July 7, 2021): 1–4. http://dx.doi.org/10.1155/2021/9960006.

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Congenital malaria is the presence of malaria parasites in a blood smear obtained from a neonate usually within 24 hours to 7 days of life. It has for long been regarded a rare condition. However, recent data indicate that congenital malaria complicates around 35.9% of live births globally, 0–37% in Sub-Saharan Africa and about 4–6.1% in Eastern Uganda. We present a 2-day-old neonate who presented with fever, irritability, and failure to breastfeed. Laboratory tests indicated that the neonate had a positive Giemsa-stained peripheral smear for Plasmodium falciparum, with a positive malaria rapi

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30

Osungbade, Kayode O., and Olubunmi O. Oladunjoye. "Prevention of Congenital Transmission of Malaria in Sub-Saharan African Countries: Challenges and Implications for Health System Strengthening." Journal of Tropical Medicine 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/648456.

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Objectives. Review of burden of congenital transmission of malaria, challenges of preventive measures, and implications for health system strengthening in sub-Saharan Africa.Methods. Literature from Pubmed (MEDLINE), Biomed central, Google Scholar, and Cochrane Database were reviewed.Results. The prevalence of congenital malaria in sub-Saharan Africa ranges from 0 to 23%. Diagnosis and existing preventive measures are constantly hindered by weak health systems and sociocultural issues. WHO strategic framework for prevention: intermittent preventive therapy (IPT), insecticide-treated nets (ITNs

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31

Paghadar, Komal. "Congenital Malaria in a Neonate - An Unusual Case Report." International Journal of Science and Research (IJSR) 11, no. 8 (2022): 810–11. http://dx.doi.org/10.21275/sr22812102117.

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32

Omalu, Innocent Chukwuemeka James, Charles Mgbemena, Amaka Mgbemena, et al. "Prevalence of Congenital Malaria in Minna, North Central Nigeria." Journal of Tropical Medicine 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/274142.

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The study was designed to determine the true prevalence of congenital, cord, and placental malaria in General Hospital Minna, North Central Nigeria. Peripheral blood smears of near-term pregnant women, as well as the placental, cord, and peripheral blood smears of their newborn babies, were examined for malaria parasites, using the Giemsa staining technique. Out of 152 pregnant women screened, 21 (13.82%) of them were infected with malaria parasites. Of the 152 new born babies, 4 (2.63%) showed positive peripheral parasitaemia. Placental parasitaemia was 7/152 (4.61%), while cord blood parasit

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33

&NA;. "CONGENITAL MALARIA AS A RESULT OF PLASMODIUM MALARIAE: NORTH CAROLINA, 2000." Pediatric Infectious Disease Journal 21, no. 7 (2002): 714. http://dx.doi.org/10.1097/00006454-200207000-00028.

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34

de Pontual, L., I. Poilane, F. Ledeur, et al. "Report of a Case of Congenital Malaria Plasmodium malariae in France." Journal of Tropical Pediatrics 52, no. 6 (2006): 448–50. http://dx.doi.org/10.1093/tropej/fml049.

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35

Menendez, Clara, and Alfredo Mayor. "Congenital malaria: The least known consequence of malaria in pregnancy." Seminars in Fetal and Neonatal Medicine 12, no. 3 (2007): 207–13. http://dx.doi.org/10.1016/j.siny.2007.01.018.

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36

Thapa, B. R., A. Narang, and O. N. Bhakoo. "Neonatal Malaria: a Clinical Study of Congenital and Transfusional Malaria." Journal of Tropical Pediatrics 33, no. 5 (1987): 266–68. http://dx.doi.org/10.1093/tropej/33.5.266.

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37

Kaur, Prabhjot, Arun Bhatia, Kanav Midha, and Mampi Debnath. "Malaria: A Cause of Anemia and Its Effect on Pregnancy." World Journal of Anemia 1, no. 2 (2017): 51–62. http://dx.doi.org/10.5005/jp-journals-10065-0012.

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ABSTRACT Malaria is one of the major health problems in the world. It remains an important cause of very high human morbidity and mortality, especially, among children and pregnant women. It results from the infection of parasites belonging to the genus Plasmodium. Plasmodium falciparum and Plasmodium vivax are the major pathogens responsible for causing human malaria. Approximately 75% of cases are caused by P. falciparum and associated with the mortality rate of approximately 0.5 to 1.0%. Both P. falciparum and P. vivax induce anemia during their erythrocytic stages of infection. Most of the

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38

B, Ouattara, Kanthé D, Kassogué A, et al. "Prevalence of Malaria among Newborns at the Markala CSRef." Scholars International Journal of Traditional and Complementary Medicine 8, no. 01 (2025): 1–7. https://doi.org/10.36348/sijtcm.2025.v08i01.001.

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Malaria is a serious and potentially fatal parasitic infectious disease caused by several species of parasite belonging to the Plasmodium genus. The female Anopheles injects the parasite into humans in the form of a "sporozoite". This rapidly migrates via the bloodstream to the liver. Transmission can occur through mother-to-child transmission and transfusion of infected blood products. Objective: To study the prevalence of malaria among newborn babies in the paediatric ward of the CSRéf in Markala. Methodology: Cross-sectional, retrospective, descriptive study from 1st January to 30th Decembe

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39

A. S., Kireeti, Brahmanandam Lingudu, Prasoona Devireddy, Aruna Cheni Maruti, and Grace Esther Gangaraju. "CONGENITAL MALARIA PRESENTING AS NEONATAL SEPSIS." Journal of Evidence Based Medicine and Healthcare 6, no. 38 (2019): 2606–7. http://dx.doi.org/10.18410/jebmh/2019/537.

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40

Larkin, G. L., and P. E. Thuma. "Congenital Malaria in a Hyperendemic Area." American Journal of Tropical Medicine and Hygiene 45, no. 5 (1991): 587–92. http://dx.doi.org/10.4269/ajtmh.1991.45.587.

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41

Mandliya, Dr Jagdish Chandra, and Dr Rajesh Gupta. "Congenital malaria: Is it really rare?" International Journal of Medical Research and Review 1, no. 4 (2013): 195–202. http://dx.doi.org/10.17511/ijmrr.2013.i04.12.

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Poespoprodjo, Jeanne R., Nicholas M. Anstey, Afdal Hasanuddin, et al. "Severe Congenital Malaria Acquired in utero." American Journal of Tropical Medicine and Hygiene 82, no. 4 (2010): 563–65. http://dx.doi.org/10.4269/ajtmh.2010.09-0744.

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Prior, A. R., F. Prata, A. Mouzinho, and J. G. Marques. "Congenital malaria in a European country." Case Reports 2012, dec11 1 (2012): bcr2012007310. http://dx.doi.org/10.1136/bcr-2012-007310.

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44

Spencer, T. E. T. "Congenital malaria in Papua New Guinea." Transactions of the Royal Society of Tropical Medicine and Hygiene 84, no. 6 (1990): 898. http://dx.doi.org/10.1016/0035-9203(90)90121-t.

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45

Lehner, P. J., and C. J. A. Andrews. "Congenital malaria in Papua New Guinea." Transactions of the Royal Society of Tropical Medicine and Hygiene 82, no. 6 (1988): 822–26. http://dx.doi.org/10.1016/0035-9203(88)90006-5.

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46

Hewson, MP, K. Simmer, and T. Blackmore. "Congenital malaria in a preterm infant." Journal of Paediatrics and Child Health 39, no. 9 (2003): 713–15. http://dx.doi.org/10.1046/j.1440-1754.2003.00275.x.

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47

Cummins, D., C. Brain, and S. C. Davies. "Congenital malaria in one identical twin." Journal of Clinical Pathology 43, no. 7 (1990): 609. http://dx.doi.org/10.1136/jcp.43.7.609-a.

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48

Harrington, Whitney E., and Patrick E. Duffy. "Congenital malaria: rare but potentially fatal." Pediatric Health 2, no. 2 (2008): 235–48. http://dx.doi.org/10.2217/17455111.2.2.235.

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49

Lesko, Catherine R., Paul M. Arguin, and Robert D. Newman. "Congenital Malaria in the United States." Archives of Pediatrics & Adolescent Medicine 161, no. 11 (2007): 1062. http://dx.doi.org/10.1001/archpedi.161.11.1062.

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50

Kuku-Kuye, Taiwo O., Oluwaseun O. Orekoya, Adetokunbo O. Fabamwo, Oluwarotimi I. Akinola, and Ayokunle M. Olumodeji. "Congenital and Placenta Malaria and Newborn Birth Weight in Asymptomatic HIV Positive Pregnant Women at Term." International Journal of Innovative Research in Medical Science 7, no. 05 (2022): 248–53. http://dx.doi.org/10.23958/ijirms/vol07-i05/1404.

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Background: Human Immuno-deficiency Virus (HIV) and Malaria infection independently are major contributors to adverse perinatal outcomes in sub-Saharan Africa. A co-infection of both in pregnancy has been associated with more deleterious birth weight- related neonatal outcomes. We assessed for congenital malaria and evaluated the birth weights of babies born to HIV positive mothers with and without evidence of placenta malaria at term delivery. Methods: This was a comparative cross-sectional study in which 90 low-risk, HIV positive pregnant women on highly active retroviral therapy (HAART), as

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