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Journal articles on the topic 'CONGO-RED STAINING'

Author: Grafiati

Published: 11 September 2023

Last updated: 31 July 2025

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1

Emmett, Ern. "Microscopical techniques: staining with Congo Red." Field Mycology 4, no. 2 (2003): 72. http://dx.doi.org/10.1016/s1468-1641(10)60194-6.

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2

Guselnikova, Valeriia V., Elena A. Fedorova, Alexandra Ja Gudkova, Michael M. Shavlovsky, and Dmitrii E. Korzhevskii. "Transthyretin amyloid cardiomyopathy. Features of histological diagnosis: study design." Terapevticheskii arkhiv 94, no. 4 (2022): 473–78. http://dx.doi.org/10.26442/00403660.2022.04.201464.

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Aim. To compare efficiency and specific features of transthyretin amyloid staining by different histological dyes and thus to assess their suitability for diagnostic purposes. Materials and methods. Samples of left and right heart ventricles were taken from patients over 70 years-old of both genders (n=10) with immunohistochemically verified transthyretin amyloidosis (ATTR). All samples were stained with Congo red, Alcian blue, toluidine blue and methylene violet. Results. Specificity and sensitivity of Congo red staining was comparable to those of immunohistochemical staining. For

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3

Kibby, Geoffrey. "Staining cap cuticle with congo red dye." Field Mycology 7, no. 1 (2006): 36. http://dx.doi.org/10.1016/s1468-1641(10)60359-3.

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4

Kadota, Ayumi, Susumu Iwaide, Shinya Miyazaki, Ikki Mitsui, Noboru Machida, and Tomoaki Murakami. "Pathology and Proteomics-Based Diagnosis of Localized Light-Chain Amyloidosis in Dogs and Cats." Veterinary Pathology 57, no. 5 (2020): 658–65. http://dx.doi.org/10.1177/0300985820934113.

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Amyloidosis is classified according to the amyloid precursor protein, and accurate diagnosis of the amyloidosis type may guide appropriate treatment. Immunohistochemistry and Congo red staining are the most frequently used methods used to distinguish types of amyloidosis, but problems with specificity and sensitivity indicate the need for an alternative diagnostic method. In this study, we evaluated laser microdissection-liquid chromatography-tandem mass spectrometry (LMD-LC-MS/MS) for the diagnosis of amyloid light-chain (AL) amyloidosis in animals. Plasmacytomas with amyloid deposits from 15

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Schulze, C., M. Brügmann, M. Böer, H. P. Brandt, J. Pohlenz, and R. P. Linke. "Generalized AA-amyloidosis in Siberian Tigers (Panthera tigris altaica) with Predominant Renal Medullary Amyloid Deposition." Veterinary Pathology 35, no. 1 (1998): 70–74. http://dx.doi.org/10.1177/030098589803500108.

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Generalized amyloidosis with predominant renal medullary amyloid deposition was found in four closely related Siberian tigers ( Panthera tigris altaica) suffering from end stage kidney diseases. Only minimal to mild amounts of amyloid were deposited in various organs outside the kidneys with individually variable organ involvement. The Congo red staining affinity of amyloid deposits was sensitive to potassium permanganate oxidation. The deposits were further characterized as being of the amyloid-A (AA) type by immunohistochemistry using the mouse monoclonal antibody mc4 directed against a cons

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6

NORN, M. S. "CONGO RED VITAL STAINING OF CORNEA AND CONJUNCTIVA." Acta Ophthalmologica 54, no. 5 (2009): 601–10. http://dx.doi.org/10.1111/j.1755-3768.1976.tb01289.x.

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7

Gruber, A. D., and R. P. Linke. "Generalized AA-Amyloidosis in a Bat (Pipistrellus pipistrellus)." Veterinary Pathology 33, no. 4 (1996): 428–30. http://dx.doi.org/10.1177/030098589603300409.

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Generalized amyloidosis was found to be the cause of death in a female adult insectivorous pipistrelle bat ( Pipistrellus pipistrellus) after chronic wound inflammation. Large amounts of amyloid were detected in liver, spleen, kidneys, stomach, intestine, lymphatic tissues, and endocrine and salivary glands. Congo red staining and green birefringence identified amyloid; the Congo red staining was sensitive to potassium permanganate oxidation. The amyloid was further classified immunohistochemically. The deposits reacted with two anti-human-AA-amyloid monoclonal antibodies in a peroxidase-antip

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8

Bély, M. "Histochemical Differential Diagnosis and Polarization Optical Analysis of Amyloid and Amyloidosis." Scientific World JOURNAL 6 (2006): 154–68. http://dx.doi.org/10.1100/tsw.2006.35.

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Amyloidosis is characterized by extracellular deposition of protein fibrils of chemically heterogeneous composition. Early recognition and identification of amyloid deposits allows an early start of therapy, which may entail a better prognosis. Congo red staining according to Romhányi (1971) is a highly specific and sensitive method for early microscopic recognition of amyloidosis. The main and most important types of amyloidosis may be distinguished by classic histochemical methods of performate pretreatment according to Romhányi (1979), or by KMnO4oxidation according to Wright (1977) followe

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9

Gruber, A. D., and R. P. Linke. "Generalized AA-Amyloidosis in a Bat (Pipistrellus pipistrellus)." Veterinary Pathology 33, no. 4 (1996): 428–30. https://doi.org/10.5281/zenodo.13491265.

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(Uploaded by Plazi for the Bat Literature Project) Generalized amyloidosis was found to be the cause of death in a female adult insectivorous pipistrelle bat (Pipistrellus pipistrellus) after chronic wound inflammation. Large amounts of amyloid were detected in liver, spleen, kidneys, stomach, intestine, lymphatic tissues, and endocrine and salivary glands. Congo red staining and green birefringence identified amyloid; the Congo red staining was sensitive to potassium permanganate oxidation. The amyloid was further classified immunohistochemically. The deposits reacted with two anti-human-AA-a

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10

Gruber, A. D., and R. P. Linke. "Generalized AA-Amyloidosis in a Bat (Pipistrellus pipistrellus)." Veterinary Pathology 33, no. 4 (1996): 428–30. https://doi.org/10.5281/zenodo.13491265.

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(Uploaded by Plazi for the Bat Literature Project) Generalized amyloidosis was found to be the cause of death in a female adult insectivorous pipistrelle bat (Pipistrellus pipistrellus) after chronic wound inflammation. Large amounts of amyloid were detected in liver, spleen, kidneys, stomach, intestine, lymphatic tissues, and endocrine and salivary glands. Congo red staining and green birefringence identified amyloid; the Congo red staining was sensitive to potassium permanganate oxidation. The amyloid was further classified immunohistochemically. The deposits reacted with two anti-human-AA-a

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11

Gruber, A. D., and R. P. Linke. "Generalized AA-Amyloidosis in a Bat (Pipistrellus pipistrellus)." Veterinary Pathology 33, no. 4 (1996): 428–30. https://doi.org/10.5281/zenodo.13491265.

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(Uploaded by Plazi for the Bat Literature Project) Generalized amyloidosis was found to be the cause of death in a female adult insectivorous pipistrelle bat (Pipistrellus pipistrellus) after chronic wound inflammation. Large amounts of amyloid were detected in liver, spleen, kidneys, stomach, intestine, lymphatic tissues, and endocrine and salivary glands. Congo red staining and green birefringence identified amyloid; the Congo red staining was sensitive to potassium permanganate oxidation. The amyloid was further classified immunohistochemically. The deposits reacted with two anti-human-AA-a

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12

Gruber, A. D., and R. P. Linke. "Generalized AA-Amyloidosis in a Bat (Pipistrellus pipistrellus)." Veterinary Pathology 33, no. 4 (1996): 428–30. https://doi.org/10.5281/zenodo.13491265.

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(Uploaded by Plazi for the Bat Literature Project) Generalized amyloidosis was found to be the cause of death in a female adult insectivorous pipistrelle bat (Pipistrellus pipistrellus) after chronic wound inflammation. Large amounts of amyloid were detected in liver, spleen, kidneys, stomach, intestine, lymphatic tissues, and endocrine and salivary glands. Congo red staining and green birefringence identified amyloid; the Congo red staining was sensitive to potassium permanganate oxidation. The amyloid was further classified immunohistochemically. The deposits reacted with two anti-human-AA-a

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13

Anhäuser, Lea, Gabriele Halsen, and Johannes Gerding. "Tätigkeiten mit krebserzeugenden aromatischen Aminen bei nasschemischen Analysemethoden in medizinischen Laboren – Modellierung der Exposition." ASU Arbeitsmedizin Sozialmedizin Umweltmedizin 2025, no. 02 (2025): 108–16. https://doi.org/10.17147/asu-1-417853.

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Activities with carcinogenic aromatic amines in wet-chemical analysis methods in medical laboratories – exposure modelling Objective: In medical laboratories, exposure to the carcinogenic aromatic amine benzidine or the benzidine-releasing azo dye Congo red was previously and still is occasionally possible when carrying out certain laboratory analyses. These amines can be the cause of urinary bladder carcinoma. To determine the inhalation and dermal exposure in wet-chemical analysis methods, activities are described and the customary exposure is modelled. Methods: Five exemplary wet-chemical a

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14

Hossain, Bassam, and Sumair Ahmad. "S2605 GI Amyloidosis: A Case of Congo Red Staining and Anemia." American Journal of Gastroenterology 117, no. 10S (2022): e1726-e1726. http://dx.doi.org/10.14309/01.ajg.0000867060.62730.83.

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15

Perez Gonzalez, D., G. Gonzalez, A. Fret Cruz, C. M. Perez, C. Rosario Martinez, and J. R. Aleman-Ortiz. "Unconventional Presentation of Amyloidosis: A Case of Negative Congo Red Staining." American Journal of Respiratory and Critical Care Medicine 211, Abstracts (2025): A1998. https://doi.org/10.1164/ajrccm.2025.211.abstracts.a1998.

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16

Bennett, J. D. C., and C. R. Chowdhury. "Primary amyloidosis of the larynx." Journal of Laryngology & Otology 108, no. 4 (1994): 339–40. http://dx.doi.org/10.1017/s0022215100126702.

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AbstractThe history, examination and operative findings of primary amyloidosis of the larynx are very suggestive of carcinoma, indicating the need for careful histological examination. Staining with Congo red shows a characteristic birefringence. Systemic amyloidosis may be present

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17

Phaosawasdi, Kamthorn, Yingluk Sritunyarat, Chawin Lopimpisuth, Nutbordee Nalinthassanai, Yongkasem Vorasettakarnkij, and Pradermchai Kongkam. "Prevalence of achlorhydria in an Asian population detected using Congo red staining during routine gastroscopy: 22 years’ experience from a single centre." BMJ Open Gastroenterology 9, no. 1 (2022): e000976. http://dx.doi.org/10.1136/bmjgast-2022-000976.

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ObjectiveWe aimed to study the prevalence of achlorhydria (AC) in a large Asian population.DesignMedical records of patients who underwent oesophagogastroduodenoscopy (OGD) with Congo red staining method at the Vichaiyut Hospital from January 2010 to December 2019 were retrospectively reviewed.ResultsA total of 3597 patients was recruited; 223 were excluded due to concurrent use of proton pump inhibitors. Eighteen from 3374 patients (0.53%) had AC. Seven patients were presented with permanent AC (5F, 2M) (median age=69 years; range 58–92). Among 11 patients with temporary AC (5M, 6F: mean age

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18

Djunic, Irena, Dragica Tomin, Maja Perunicic, et al. "Diagnosis and the treatment of primary amyloidosis." Vojnosanitetski pregled 67, no. 9 (2010): 781–85. http://dx.doi.org/10.2298/vsp1009781d.

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Backgraund. Primary amyloidosis belongs to a group of monoclonal plasma cell disorders, characterized by extracellular deposition of immunoglobulin light chain fibrils in various tissues and subsequent multiorgan dysfunction. Case report. We present a 51-year-old female with 2-years history of fatigue on exertion, oedema of face, abdomen and legs, bone pain and obstipation. After diagnostic procedures such as electrophoresis and immunoelectrophoresis of serum and urine proteins, immunohistohemical staining of bone marrow biopsy specimens and Congo red staining of rectal biopsy specimens, the p

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19

DIAS, CHRISTIAN, JOHN W BOLDT, and SANDEEP K RAJAN. "PULMONARY AMYLOIDOSIS: LUNG BIOPSY STAINING WITH CONGO-RED WITHOUT ANY SYSTEMIC SPREAD." Chest 162, no. 4 (2022): A1600. http://dx.doi.org/10.1016/j.chest.2022.08.1342.

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20

V. H., Shyma, Bipin K. C., Deepa P. M., et al. "Congo Red Staining: An Effective Affordable Tool For Diagnosis Of Bovine Leptospirosis." Indian Veterinary Journal 101, no. 5 (2024): 45–47. http://dx.doi.org/10.62757/iva.2024.101.5.45-47.

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21

Maloumbi, Phany Brunelle Issanga, Junior Rocyr Ibara Onguema, Gildas Ismael Ganse, et al. "Diagnosis of Systemic AL-Type Amyloidosis Revealed by Severe Restrictive Cardiomyopathy: Case Report and Literature Review." SAS Journal of Medicine 8, no. 3 (2022): 167–70. http://dx.doi.org/10.36347/sasjm.2022.v08i03.011.

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Amyloidosis refers to a group of systemic diseases whose common feature is the extracellular accumulation of insoluble fibrillar proteins in tissues (heart, reins, digestive tract). Several types of amyloidosis have been described; the primary (AL) and the secondary (AA) forms are by far the most frequent. AL amyloidosis is rare but not exceptional disease, with a prevalence of 500new cases per year in France. It is related to be precipitation in tissues of monoclonal light chains of immunoglobulin in the form of fibrils. Its diagnosis is histological based on the biopsy analysis of an affecte

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22

BAJYA, D. R., DEEPIKA ARYA, M. RANJITH, M. C. LAKHARAN, and S. K. RAZA. "Isolation and identification of cellulose demoting symbionts from gut of subterranean termite, Odontotermes obesus." Indian Journal of Agricultural Sciences 85, no. 7 (2015): 970–72. http://dx.doi.org/10.56093/ijas.v85i7.50142.

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The study was carried out to isolate and identify the symbionts, viz. cellulose demoting bacteria and fungus in termite gut. The experiment was conducted during (February 2013- July 2013) at biotechnology laboratory, Institute of Pesticide Formulation Technology, Gurgaon (Haryana). Termites are wood eating insects and are among the most important ligno cellulose- digesting insects and possess a variety of symbiotic microorganisms in their gut. Nutrient agar, potato dextrose and Carboxy Methyl Cellulose (CMC) were used to isolate the dry bacterial strain and fungus. The cellulose is demoted in

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23

Dzekova-Vidimliski, Pavlina, Vlatko Karanfilovski, Igor G. Nikolov, et al. "Glomerulopathies with Fibrillary Deposits." PRILOZI 44, no. 2 (2023): 99–106. http://dx.doi.org/10.2478/prilozi-2023-0030.

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Abstract The glomerulopathies associated with the deposition of extracellular fibrils in the glomeruli are subdivided into Congo red positive (amyloidosis) and Congo red negative (non-amyloidotic glomerulopathies) based on Congo red staining. The non-amyloidotic glomerulopathies are divided into immunoglobulin-derived and non-immunoglobulin-derived glomerulopathies. The immunoglobulin-derived glomerulopathies: fibrillary glomerulopathy (FGn) and immunotactoid glomerulopathy (ITG) are rare glomerulopathies. The diagnosis of fibrillary-immunotactoid glomerulopathy depends on electron microscopy,

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Sharma, P., S. Pajni, N. Dhillon, D. V. Vadehra, and D. K. Dube. "Limitations of the Congo-Red staining techniques for the detection of cellulolytic activities." Biotechnology Letters 8, no. 8 (1986): 579–80. http://dx.doi.org/10.1007/bf01028087.

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25

Batool, Maria, Eamon Leen, Siobhan Glavey, Seamus K. Sreenan, and John McDermott. "Nephrotic Syndrome Following Resection of an Adrenal Incidentaloma:A Case Report." Journal of the Endocrine Society 5, Supplement_1 (2021): A144—A145. http://dx.doi.org/10.1210/jendso/bvab048.292.

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Abstract A 69 year old man had a 5 cm right adrenal lesion discovered incidentally while being investigated for a deterioration in previously well-controlled hypertension. Routine investigations including serum albumin were normal. Further investigation confirmed a non-functioning adrenal lesion. MRI revealed a ‘non-fat-containing T1 hyperintense indeterminate adrenal lesion with speckling of T2 hyperintensity, not typical for adenoma, hyperplasia, myelolipoma, haemangioma or pheochromocytoma’. An uncomplicated laparoscopic adrenalectomy was performed. Histology revealed a 118 g adrenal neopla

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Chiwar, Hassan Musa, Hajja Inna Muhammad Mailafiya, Isa Saidu Isa, and Fatima Aliyu Chiroma. "Characterization and frequency of biofilms in adenotonsillitis: a retrospective study from a tertiary hospital in North-Eastern Nigeria." International Journal of Research in Medical Sciences 11, no. 9 (2023): 3156–62. http://dx.doi.org/10.18203/2320-6012.ijrms20232762.

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Background: Adenotonsillitis, a common condition characterized by inflammation of the adenoids and tonsils, is caused by bacterial and fungal pathogens. Biofilm formation has been linked to disease chronicity and antibiotic resistance. However, the role of biofilms in adenotonsillitis remains poorly understood. This study aims to explore biofilms in adenotonsillitis biopsies, focusing on their characterization, frequency, and demographic distribution by determining the expression of polysaccharides in the biofilm matrix using Congo red stain, determining the presence and frequency of bacterial

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Lu, Chia-Ming, Mei-Ling Hou, Lie-Chwen Lin, and Tung-Hu Tsai. "Chemical and Physical Methods to Analyze a Multicomponent Traditional Chinese Herbal Prescription Using LC-MS/MS, Electron Microscope, and Congo Red Staining." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/952796.

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This study develops several chemical and physical methods to evaluate the quality of a traditional Chinese formulation, Jia-Wei-Xiao-Yao-San. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) coupled with electrospray ionization was used to measure the herbal biomarkers of saikosaponin A, saikosaponin D, ferulic acid, and paeoniflorin from this herbal formula. A scanning electron microscope (SEM) and light microscopy photographs with Congo red staining were used to identify the cellulose fibers if raw herbal powder had been added to the herbal pharmaceutical product. Moreover, water so

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Gómez-Piña, Juan José, Dulce Mariana Quiroz, Amairani Sierra-Hernández, Sergio Alberto Mendoza-Álvarez, and Olga Lidia Vera-Lastra. "[Giant tongue leading to dysphagia in light chain amyloidosis patient]." Revista Médica el Instituto Mexicano del Seguro Social 61, no. 6 (2023): 863–67. https://doi.org/10.5281/zenodo.10064470.

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<strong>Abstract</strong><strong>Introduction:</strong> Macroglossia as a clinical manifestation of systemic amyloidosis is a rare condition, occurring in less than 9% of all types of amyloidosis. The aim of this report is to present the diagnostic approach of a patient with macroglossia, providing a systematic approach and considering relevant diagnostic possibilities during their evaluation.<strong>Clinical case:</strong> We present the case of a 60-year-old man who presented with a progressively enlarging giant tongue for six months, causing dysphagia and reduced oral opening. A tongue biop

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Panicker, Vinitha V., Soumya Jagadeesan, Gopikrishnan Anjaneyan, et al. "A clinicopathological study of primary localised cutaneous amyloidosis." International Journal of Research in Dermatology 3, no. 4 (2017): 470. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20174649.

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<p class="abstract"><strong>Background:</strong> Amyloidosis is defined as extracellular deposits of heterogenic, misfolded proteins, amyloid fibrils, in various tissues. The term primary cutaneous amyloidosis (PLCA) usually includes macular amyloidosis (MA), lichen amyloidosis (LA) and nodular amyloidosis. Primary cutaneous amyloidosis is very common in Kerala probably due to socio-cultural practices. There has been no published data on PLCA from Kerala thus we undertook this study. The objectives of the study were to correlate clinical features of primary localized cutaneou

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Anil, Gaur. "Clinico - histopathological study of primary localised cutaneous amyloidosis with histopathological correlation by h&e and congo red stain." PJSR 14, no. 2 (2020): 1–4. https://doi.org/10.5281/zenodo.8223306.

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Primary localized cutaneous amyloidosis is a commonly encountered problem in our scenario. As there is paucity of Indian studies on this subject , a clinico-histopathological study is required. Moreover it resembles with other cutaneous hyperpigmented lesions so on the part of clinician it will be helpful to properly diagnose the condition. To determine various clinical variants of primary localised cutaneous amyloidosis and its clinico-histopathological correlation by H & E and Congo red staining. Study was undertaken on all new patients with primary localised cutaneous amyloidosis attend

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Seifi, Safoura, Zahra Azizi, Alten Ghanghermeh, Shahriar Eftekharian, Jahanshah Salehinejad, and Hemmat Gholinia. "Eosinophil density in common benign and malignant salivary gland tumors with congo red staining." Indian Journal of Medical and Paediatric Oncology 40, no. 2 (2019): 212. http://dx.doi.org/10.4103/ijmpo.ijmpo_217_17.

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32

Suyama, Kousuke, Hiroki Yamamoto, Takahiko Naganawa, Takeshi Iwata, and Hajimu Komada. "A plate count method for aerobic cellulose decomposers in soil by Congo red staining." Soil Science and Plant Nutrition 39, no. 2 (1993): 361–65. http://dx.doi.org/10.1080/00380768.1993.10417008.

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LINDER, E., V. P. LEHTO, and I. VIRTANEN. "AMYLOID-LIKE GREEN BIREFRINGENCE IN CYTOSKELETAL 10 nm FILAMENTS AFTER STAINING WITH CONGO RED." Acta Pathologica Microbiologica Scandinavica Section A Pathology 87A, no. 1-6 (2009): 299–306. http://dx.doi.org/10.1111/j.1699-0463.1979.tb00056.x.

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Zilberstein, Netanel F., Sanmeet Singh, Ashley T. Zilberstein, and Robert Carroll. "1770 The Utility of Congo Red Staining in Grossly and Histopathologically Silent Gastrointestinal Amyloidosis." American Journal of Gastroenterology 114, no. 1 (2019): S993—S994. http://dx.doi.org/10.14309/01.ajg.0000596612.42939.f8.

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Fedotov, Sergey A., Elizaveta M. Gerasimova, Elena S. Vashukova, et al. "Evaluation of the effectiveness of modified CRD tests in the diagnosis of preeclampsia." Journal of obstetrics and women's diseases 71, no. 4 (2022): 65–74. http://dx.doi.org/10.17816/jowd109365.

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BACKGROUND: Preeclampsia is a multisystem complication of pregnancy associated with an increased risk of maternal / perinatal morbidity and mortality. In this regard, the development and following improvement of low-cost and convenient methods for diagnosis of preeclampsia is essential for accurate prediction, quick confirmation of the diagnosis and convenient monitoring of the pathology. AIM: The aim of this study was to optimize a preeclampsia diagnosis test system based on the binding of proteins to the Congo red dye (CRD test). MATERIALS AND METHODS: The study used 70 urine sam

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Annita, Annita, Gusti Revilla, Hirowati Ali, and Almurdi Almurdi. "Adipose-Derived Mesenchymal Stem Cell (AD-MSC)-Like Cells Restore Nestin Expression and Reduce Amyloid Plaques in Aluminum Chloride (AlCl3)-Driven Alzheimer's Rat Models." Molecular and Cellular Biomedical Sciences 8, no. 3 (2024): 159. http://dx.doi.org/10.21705/mcbs.v8i3.387.

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Background: Alzheimer's disease (AD) is a neurodegenerative disorder with a significant burden on public health, and current treatments offer limited efficacy. This study investigated the effectiveness of adipose-derived mesenchymal stem cells (AD-MSCs) on the expression of the nestin gene and amyloid plaque in an aluminum chloride (AlCl3)-driven Alzheimer's rat model.Materials and methods: AD-MSCs were characterized using flow cytometry. Adult male Wistar rats were treated with/without AlCl3 and injected with/without AD-MSCs. After 5 days of AlCl3 ingestion and 4 weeks of subsequent AD-MSCs i

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Mold, Cottle, King, and Exley. "Intracellular Aluminium in Inflammatory and Glial Cells in Cerebral Amyloid Angiopathy: A Case Report." International Journal of Environmental Research and Public Health 16, no. 8 (2019): 1459. http://dx.doi.org/10.3390/ijerph16081459.

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(1) Introduction: In 2006, we reported on very high levels of aluminium in brain tissue in an unusual case of cerebral amyloid angiopathy (CAA). The individual concerned had been exposed to extremely high levels of aluminium in their potable water due to a notorious pollution incident in Camelford, Cornwall, in the United Kingdom. The recent development of aluminium-specific fluorescence microscopy has now allowed for the location of aluminium in this brain to be identified. (2) Case Summary: We used aluminium-specific fluorescence microscopy in parallel with Congo red staining and polarised l

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Tsai, Karen, Alice Chen Yu, Masha J. Livhits, Dipti Sajed, Angela M. Leung, and Dianne S. Cheung. "Systemic light-chain amyloidosis incidentally diagnosed after subtotal parathyroidectomy and thyroid lobectomy." BMJ Case Reports 14, no. 4 (2021): e241282. http://dx.doi.org/10.1136/bcr-2020-241282.

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A 74-year-old woman with a history of primary hyperparathyroidism, thyroid nodules, atrial fibrillation and pacemaker placement for sick sinus syndrome presented with fatigue, constipation and persistent lower extremity oedema. She underwent subtotal parathyroidectomy and left thyroid lobectomy. Histopathology revealed amyloidosis affecting the thyroidand parathyroids confirmed by Congo Red Staining with Mayo Clinic subtyping of light chain kappa-type amyloidosis. She was found to have combined systolic and diastolic cardiac dysfunction, carpal tunnel neuropathy and pre-diabetes suggestive of

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Kozlov, Vadim A., Sergey P. Sapozhnikov, Pavel B. Karyshev, Alena I. Fufaeva, Vera Yu Aleksandrova, and Yulia V. Vasilyeva. "TONSILOGENIC AMYLOIDOSIS." Acta medica Eurasica, no. 2 (June 25, 2021): 7–16. http://dx.doi.org/10.47026/2413-4864-2021-2-7-16.

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In connection with the report that amyloid is a functional antimicrobial substance, possibly a part of innate immunity, we suggested that amyloid may form in the palatine tonsils in chronic tonsillitis. Thirty-two patients aged 19 to 52 years underwent surgical treatment for clinically proven chronic tonsillitis. The aim of the study was to detect the fact of amyloid tonsillar lesions formation in chronic tonsillitis. We performed histological examination of tonsillo-ectomized material fixed in 10% formalin solution and filled in paraffin on 4-micron histological sections: 1) according to the

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Orrego, John J., and Joseph A. Chorny. "AMYLOID GOITER AS THE FIRST RECOGNIZABLE MANIFESTATION OF IMMUNOGLOBULIN LIGHT CHAIN AMYLOIDOSIS." AACE Clinical Case Reports 5, no. 5 (2019): e326-e329. http://dx.doi.org/10.4158/accr-2019-0161.

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Objective: Clinically apparent thyroid enlargement due to massive amounts of amyloid deposition, known as amyloid goiter, is rare. Endocrinologists should become familiar with this manifestation of systemic amyloidosis, which may be diagnosed by Congo red staining of the specimen obtained by fine-needle aspiration. Methods: We describe a 70-year-old man who presented with a slowly enlarging goiter. It was asymptomatic, predominantly left-sided, nontoxic, and multinodular with atypia of undetermined significance (Bethesda System category III) by cytology. The goiter tested negative using the Th

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Salladini, Edoardo, Frank Gondelaud, Juliet F. Nilsson, et al. "Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation." Biomolecules 11, no. 9 (2021): 1324. http://dx.doi.org/10.3390/biom11091324.

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Henipaviruses are BSL-4 zoonotic pathogens responsible in humans for severe encephalitis. Their V protein is a key player in the evasion of the host innate immune response. We previously showed that the Henipavirus V proteins consist of a long intrinsically disordered N-terminal domain (NTD) and a β-enriched C-terminal domain (CTD). These terminals are critical for V binding to DDB1, which is a cellular protein that is a component of the ubiquitin ligase E3 complex, as well as binding to MDA5 and LGP2, which are two host sensors of viral RNA. Here, we serendipitously discovered that the Hendra

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Xu, Chao-Jin, Jun-Ling Wang, Jing-Pan, and Min-Liao. "Tph2 Genetic Ablation Contributes to Senile Plaque Load and Astrogliosis in APP/PS1 Mice." Current Alzheimer Research 16, no. 3 (2019): 219–32. http://dx.doi.org/10.2174/1567205016666190301110110.

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Background: Amyloid-β (Aβ) accumulation plays a critical role in the pathogenesis of Alzheimer’s disease (AD) lesions. Deficiency of Serotonin signaling recently has been linked to the increased Aβ level in transgenic mice and humans. In addition, tryptophan hydroxylase-2 (Tph2), a second tryptophan hydroxylase isoform, controls brain serotonin synthesis. However, it remains to be determined that whether Tph2 deficient APP/PS1mice affect the formation of Aβ plaques in vivo. Methods: Both quantitative and qualitative immunochemistry methods, as well as Congo red staining were used to evaluate t

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Mutalik, Vimi Sunil, Monica Solomon, Prasanna Nichat, Sunitha Carnelio, and Raghu Radhakrishnan. "Clear Cell variant of Calcifying Epithelial Odontogenic Tumor without Calcification: A Rarity." Journal of Contemporary Dental Practice 15, no. 1 (2014): 119–21. http://dx.doi.org/10.5005/jp-journals-10024-1500.

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ABSTRACT Calcifying epithelial odontogenic tumor (CEOT) is a rare, benign, locally aggressive odontogenic epithelial tumor that affects the jaws. Although there are numerous reports on the variants of CEOT, occurrence of clear cells with complete absence of calcification has been a rarity. Histochemical analysis of tumor cells revealed glycogen granules with PAS staining, with absence of CD 1a staining in clear cells, while the amyloid-like deposit associated with clear cells showed green birefringence with Congo red. We report an unusual variant of CEOT occurring in a 27 years old male patien

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Bély, Miklós, and Josef Makovitzky. "Sensitivity and specificity of Congo red staining according to Romhányi. Comparison with Puchtler's or Bennhold's methods." Acta Histochemica 108, no. 3 (2006): 175–80. http://dx.doi.org/10.1016/j.acthis.2006.03.017.

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Miguel-Hidalgo, José Javier, Antón Alvarez, and Ramón Cacabelos. "Plasticity of Congo red staining displayed by subpopulations of neurons within the rat central nervous system." Cell and Tissue Research 293, no. 1 (1998): 75–86. http://dx.doi.org/10.1007/s004410051099.

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Mehta, Seema, and Yudhishthir S. Rajput. "A Method for Staining of Proteins in Nitrocellulose Membrane and Acrylamide Gel Using Congo Red Dye." Analytical Biochemistry 263, no. 2 (1998): 248–51. http://dx.doi.org/10.1006/abio.1998.2805.

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Liu, Song. "Study on the Factors and Degradation of Cellulose Degradation Bacteria." Advanced Materials Research 864-867 (December 2013): 40–43. http://dx.doi.org/10.4028/www.scientific.net/amr.864-867.40.

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This study obtained 12 microbial degradation of cellulose from perennial accumulation of cellulose waste soil, through Congo red staining, isolated high efficient bacteria N4 degradation of cellulose. The N4 strain degradation single factor experiment showed that: carbon concentration, incubation temperature and initial pH value influence on the degradation of filter paper. Through the orthogonal experimental study obtained: when the concentration of filter paper is 0.5%, culture temperature is 30 °C, initial pH is 8, N4 strain filter paper degradation rate reached optimal, filter paper weight

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Kumar, Susheel. "Skin Involvement in Primary Systemic Amyloidosis." Mediterranean Journal of Hematology and Infectious Diseases 5, no. 1 (2013): e2013005. http://dx.doi.org/10.4084/mjhid.2013.005.

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Primary systemic amyloidosis is a rare disease. It primarily involves kidney, heart, peripheral nerves and liver. Intracutaneous hemorrhage manifesting in the form of petechiae, purpura and ecchymoses due to infiltration of blood vessel walls by amyloid deposits are the most common skin lesions. We report a case of primary systemic amyloidosis with multiple, non-itchy, papular lesions in lower eyelids and lower chest wall bilaterally. Diagnosis was confirmed in this case by biopsy of skin lesions using congo red staining. Papular eruptions as seen in index patient are relatively uncommon form

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Cowan, D. F. "Amyloidosis in the Bottlenose Dolphin, Tursiops truncatus." Veterinary Pathology 32, no. 3 (1995): 311–14. http://dx.doi.org/10.1177/030098589503200314.

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Four cases of amyloidosis were recognized in a study population of 21 (19%) bottlenose dolphins ( Tursiops truncatus) examined as part of an investigation of the causes of cetacean strandings along the Texas Gulf Coast. Amyloid deposition was mainly and most prominently in the corticomedullary regions of the kidneys and less consistently in the vessels of the spleen, lung, and heart and around acini of the palatal salivary gland and the thyroid gland. Pretreatment of sections with permanganate and sulfuric acid greatly diminished Congo red staining, suggesting the dolphin amyloid is of the AA

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Hansen, Charlotte Toftmann, Hanne E. H. Møller, Aleksandra Maria Rojek, Niels Marcussen, Hans Christian Beck, and Niels Abildgaard. "Combined Subcutaneous Fat Aspirate and Skin Tru-Cut Biopsy for Amyloid Screening in Patients with Suspected Systemic Amyloidosis." Molecules 26, no. 12 (2021): 3649. http://dx.doi.org/10.3390/molecules26123649.

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Screening for systemic amyloidosis is typically carried out with abdominal fat aspirates with varying reported sensitivities. Fat aspirates are preferred for use in primary screening instead of organ biopsies as they are less invasive and thereby minimize the potential risk of complications. At Odense Amyloidosis Center, we performed a prospective study on whether the combined use of fat aspirate and tru-cut skin biopsy could increase the diagnostic sensitivity. Both fat aspirates and skin biopsies were screened with Congo Red staining, and positive biopsies were subsequently subtyped using im

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