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1

Pu, Xin Zheng. "Finite Element Analysis of Assembly Body of Conical Pick." Applied Mechanics and Materials 397-400 (September 2013): 573–76. http://dx.doi.org/10.4028/www.scientific.net/amm.397-400.573.

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In order to improve the structure mechanics performance of assembly body of conical pick, the finite element method was taken to analyse assembly body of conical pick based on rock cutting theory, and the distortion law of stress and displacement of carbide tip, pick arbor and pick holder were obtained. The results show that the maximum stress appearing in pick carbide tip and its weld site is 371MPa, maximum stress of pick holder appearing in its weld site is 157MPa. Consequently, the quality of the weld should be ensured in processing and manufacturing or welding installation to reduce the p
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2

Woodward, Cora L., Sarah N. Cheng, and Grant J. Jensen. "Electron Cryotomography Studies of Maturing HIV-1 Particles Reveal the Assembly Pathway of the Viral Core." Journal of Virology 89, no. 2 (2014): 1267–77. http://dx.doi.org/10.1128/jvi.02997-14.

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ABSTRACTTo better characterize the assembly of the HIV-1 core, we have used electron cryotomography (ECT) to image infected cells and the viral particles cryopreserved next to them. We observed progressive stages of virus assembly and egress, including flower-like flat Gag lattice assemblies, hemispherical budding profiles, and virus buds linked to the plasma membrane via a thin membrane neck. The population of budded viral particles contains immature, maturation-intermediate, and mature core morphologies. Structural characteristics of the maturation intermediates suggest that the core assembl
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3

Renner, Nadine, Donna L. Mallery, K. M. Rifat Faysal, et al. "A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly." PLOS Pathogens 17, no. 2 (2021): e1009164. http://dx.doi.org/10.1371/journal.ppat.1009164.

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The HIV capsid self-assembles a protective conical shell that simultaneously prevents host sensing whilst permitting the import of nucleotides to drive DNA synthesis. This is accomplished through the construction of dynamic, highly charged pores at the centre of each capsid multimer. The clustering of charges required for dNTP import is strongly destabilising and it is proposed that HIV uses the metabolite IP6 to coordinate the pore during assembly. Here we have investigated the role of inositol phosphates in coordinating a ring of positively charged lysine residues (K25) that forms at the bas
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4

Vinh, Le Quang, and Nguyen Manh Cuong. "Dynamic analysis of FG stepped truncated conical shells surrounded by Pasternak elastic foundations." Vietnam Journal of Mechanics 42, no. 2 (2020): 133–52. http://dx.doi.org/10.15625/0866-7136/14749.

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This research presents a continuous element model for solving vibration problems of FG stepped truncated conical shells having various material properties and surrounded by Pasternak foundations. Based on the First Order Shear Deformation Theory (FSDT) and the equations of the FGM conical shells, the dynamic stiffness matrix is obtained for each segment of the shell having constant thickness. The interesting assembly procedure of continuous element method (CEM) is employed for joining those segments in order to analyze the dynamic behavior of the FG stepped truncated conical shells an assembly
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5

Zhang, Yiming, Jiqiang Tang, and Tong Wen. "A Modified Transfer Matrix Method for Modal Analysis of Stepped Rotor Assembly Applied in the Turbomolecular Pump." Shock and Vibration 2022 (February 27, 2022): 1–13. http://dx.doi.org/10.1155/2022/3692081.

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An accurate modal analysis of the stepped rotor assembly is significant in the design process of rotors. The transfer matrix method (TMM) is widely used in the modal analysis of the rotor. However, the influences of the step and the assembling modes are not considered in the traditional TMM. In this paper, a modified transfer matrix method is presented for the modal calculation of the rotor in the turbomolecular pump. The stiffness reduction of stepped segments and the effect of assembled components are considered in this modified method. First of all, the traditional transfer matrix model is
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6

Ghimire, Bhagirath, Endre J. Szili, and Robert D. Short. "A conical assembly of six plasma jets for biomedical applications." Applied Physics Letters 121, no. 8 (2022): 084102. http://dx.doi.org/10.1063/5.0104481.

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A conical assembly of six plasma jets arranged in a rectangular pattern for biomedical applications is presented. The conical configuration increases the separation distance between individual tubes within the assembly that reduces interference between individual plasma jets and enables the jets to converge at the output, facilitating more uniform treatment as opposed to plasma jet arrays operated in parallel. Electrical and optical diagnostics of the plasma discharges and measurements of H2O2 and [Formula: see text] production in de-ionized water are used to characterize the potential suitabi
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7

Lázaro, Guillermo R., Bogdan Dragnea, and Michael F. Hagan. "Self-assembly of convex particles on spherocylindrical surfaces." Soft Matter 14, no. 28 (2018): 5728–40. http://dx.doi.org/10.1039/c8sm00129d.

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Simulations and continuum theory of self-assembly of conical subunits around a spherocylindrical template show the tuning the template mean curvature, Gaussian curvature, and curvature anisotropy enables the controlled formation of a rich array of assembly geometries.
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8

Chen, Yan, and Li Bao An. "Simulation of Electric Field for Carbon Nanotube Assembly by Dielectrophoresis." Advanced Materials Research 941-944 (June 2014): 421–24. http://dx.doi.org/10.4028/www.scientific.net/amr.941-944.421.

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In the process of carbon nanotube assembly by dielectrophoresis, the geometry and spacing of electrodes are significantly affecting the assembly precision. In the simulation process, we showed the geometrical shape of conical, round and rectangular electrode and compared the electric field distribution with these electrodes. Compared with single electrode pairs, comb electrodes can achieve high-yield manipulation. Simulation results show that when the distance between adjacent electrode pairs is larger than twice electrode width, it will avoid electric field superimposition. A method of using
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9

James, Leo C. "How HIV-1 Uses the Metabolite Inositol Hexakisphosphate to Build Its Capsid." Viruses 17, no. 5 (2025): 689. https://doi.org/10.3390/v17050689.

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The HIV-1 capsid is one of virology’s most iconic structures, yet how it assembles has long remained elusive. Remarkably, the capsid is made from just a single protein, CA, which forms a lattice of ~250 hexamers and exactly 12 pentamers. Conical capsids form inside budded virions during maturation, but early efforts to reproduce this in vitro resulted instead in open-ended tubes with a purely hexameric lattice. The missing component in capsid assembly was finally identified as the metabolite inositol hexakisphosphate (IP6). Simply mixing soluble CA protein with IP6 is sufficient to drive the s
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10

Belarifi, Farid, and E. Bayraktar. "The Tredgold Method in Reverse Engineering to Check the Assembly of a Conical Spur Gear Using CAD." Advanced Materials Research 264-265 (June 2011): 1598–603. http://dx.doi.org/10.4028/www.scientific.net/amr.264-265.1598.

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Defining and generating a working drawing of a conical spur gear to replace an original piece requires geometrical and dimensional constraints, especially when the cutting module is determined by reverse engineering. We propose an approach using Computer aided design (CAD) to establish the drawing definitions and to verify the assembly of the conical spur gear. We have developed the model drawing according to the standard International Standard Organisation (ISO), in which we introduce a new non-existent coast into the current dimensioning and check the assembly using the Tredgold method, whic
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11

Lepoitevin, Mathilde, Bastien Jamilloux, Mikhael Bechelany, Emmanuel Balanzat, Jean-Marc Janot, and Sebastien Balme. "Fast and reversible functionalization of a single nanopore based on layer-by-layer polyelectrolyte self-assembly for tuning current rectification and designing sensors." RSC Advances 6, no. 38 (2016): 32228–33. http://dx.doi.org/10.1039/c6ra03698h.

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12

von Schwedler, Uta K., Kirsten M. Stray, Jennifer E. Garrus, and Wesley I. Sundquist. "Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein." Journal of Virology 77, no. 9 (2003): 5439–50. http://dx.doi.org/10.1128/jvi.77.9.5439-5450.2003.

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ABSTRACT The human immunodeficiency virus type 1 initially assembles and buds as an immature particle that is organized by the viral Gag polyprotein. Gag is then proteolyzed to produce the smaller capsid protein CA, which forms the central conical capsid that surrounds the RNA genome in the mature, infectious virus. To define CA surfaces that function at different stages of the viral life cycle, a total of 48 different alanine-scanning surface mutations in CA were tested for their effects on Gag protein expression, processing, particle production and morphology, capsid assembly, and infectivit
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13

Igamberdiev, Kholmurot Khaydarovich, and Zafarjon Saddin ugli Turdaliev. "AIR-LOCK COTTON HARVESTING EQUIPMENT." EURASIAN JOURNAL OF ACADEMIC RESEARCH 1, no. 1 (2021): 521–27. https://doi.org/10.5281/zenodo.4720077.

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14

Rodal, Avital A., Lukasz Kozubowski, Bruce L. Goode, David G. Drubin, and John H. Hartwig. "Actin and Septin Ultrastructures at the Budding Yeast Cell Cortex." Molecular Biology of the Cell 16, no. 1 (2005): 372–84. http://dx.doi.org/10.1091/mbc.e04-08-0734.

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Budding yeast has been a powerful model organism for studies of the roles of actin in endocytosis and septins in cell division and in signaling. However, the depth of mechanistic understanding that can be obtained from such studies has been severely hindered by a lack of ultrastructural information about how actin and septins are organized at the cell cortex. To address this problem, we developed rapid-freeze and deep-etch techniques to image the yeast cell cortex in spheroplasted cells at high resolution. The cortical actin cytoskeleton assembles into conical or mound-like structures composed
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15

Ganser-Pornillos, Barbie K., Uta K. von Schwedler, Kirsten M. Stray, Christopher Aiken, and Wesley I. Sundquist. "Assembly Properties of the Human Immunodeficiency Virus Type 1 CA Protein." Journal of Virology 78, no. 5 (2004): 2545–52. http://dx.doi.org/10.1128/jvi.78.5.2545-2552.2004.

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ABSTRACT During retroviral maturation, the CA protein oligomerizes to form a closed capsid that surrounds the viral genome. We have previously identified a series of deleterious surface mutations within human immunodeficiency virus type 1 (HIV-1) CA that alter infectivity, replication, and assembly in vivo. For this study, 27 recombinant CA proteins harboring 34 different mutations were tested for the ability to assemble into helical cylinders in vitro. These cylinders are composed of CA hexamers and are structural models for the mature viral capsid. Mutations that diminished CA assembly clust
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16

Dharan, Raviv, Asaf Shemesh, Abigail Millgram, et al. "Hierarchical Assembly Pathways of Spermine-Induced Tubulin Conical-Spiral Architectures." ACS Nano 15, no. 5 (2021): 8836–47. http://dx.doi.org/10.1021/acsnano.1c01374.

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17

Fessler, H., T. H. Hyde, and L. V. Lewis. "Assembly stresses and deflection of conical-faced flanges without gaskets." International Journal of Mechanical Sciences 33, no. 8 (1991): 623–35. http://dx.doi.org/10.1016/0020-7403(91)90032-x.

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18

Zhang, Zhiqing, Maozhou He, Shimeng Bai, et al. "T = 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display." Viruses 10, no. 12 (2018): 667. http://dx.doi.org/10.3390/v10120667.

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The HIV-1 mature capsid (CA) assumes an amorphous, fullerene conical configuration due to its high flexibility. How native CA self-assembles is still unclear despite having well-defined structures of its pentamer and hexamer building blocks. Here we explored the self-assembly of an engineered capsid protein built through artificial disulfide bonding (CA N21C/A22C) and determined the structure of one fraction of the globular particles. CA N21C/A22C was found to self-assemble into particles in relatively high ionic solutions. These particles contained disulfide-bonding hexamers as determined via
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19

Turof, Mihaela. "Reconstitution of the geometric elements of a conic gear." Scientific Bulletin of Naval Academy XXIII, no. 1 (2020): 55–65. http://dx.doi.org/10.21279/1454-864x-20-i1-008.

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Conical gears are used if the axes of the shafts between which the rotation movement is transmitted are concurrent. The technology of execution of these gears is more demanding, they are more sensitive to the deviations of execution and / or assembly and introduce large axial forces, which complicates, to some extent, the construction of the supports of the wheel support shafts. The straight-toothed conical gears, with relatively simple wheels for technological purposes, are used only at low peripheral speeds (𝑣 < 3 𝑚/𝑠), when step deviations and those of the tooth profiles do not yet produ
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20

Yang, Hsueh-Cheng, and Wen-Jun Liang. "A helical gear with discrete ring-involute teeth." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 234, no. 8 (2019): 1554–68. http://dx.doi.org/10.1177/0954406219893392.

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This study produces a skewed-imaginary planar rack cutter with discrete conical teeth that is used to create a helical gear with discrete ring-involute teeth. A mathematical equation for the skewed-imaginary rack cutter with discrete conical teeth is firstly solved. The coordinate system for the rack cutter and gear pair is then established and a family of the rack-cutter surfaces is obtained using homogeneous coordinate transformation. The relative velocity method is used to produce the equation for meshing between the rack cutter and the gear pair. Substituting the equation of meshing into t
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21

Fontana, Juan, Kellie A. Jurado, Naiqian Cheng, et al. "Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation." Journal of Virology 89, no. 19 (2015): 9765–80. http://dx.doi.org/10.1128/jvi.01522-15.

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ABSTRACTDuring virion maturation, HIV-1 capsid protein assembles into a conical core containing the viral ribonucleoprotein (vRNP) complex, thought to be composed mainly of the viral RNA and nucleocapsid protein (NC). After infection, the viral RNA is reverse transcribed into double-stranded DNA, which is then incorporated into host chromosomes by integrase (IN) catalysis. Certain IN mutations (class II) and antiviral drugs (allosteric IN inhibitors [ALLINIs]) adversely affect maturation, resulting in virions that contain “eccentric condensates,” electron-dense aggregates located outside seemi
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22

Bolotov, M. A., V. A. Pechenin, N. V. Ruzanov, and D. M. Balyakin. "Neural network model in digital prediction of geometric parameters for relative position of the aircraft engine parts." Information Technology and Nanotechnology, no. 2416 (2019): 87–94. http://dx.doi.org/10.18287/1613-0073-2019-2416-87-94.

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The quality of aircraft and rocket engines depends primarily on the geometric accuracy of assembly units and parts. Mathematical models implemented in the form of computer models are used to predict quality indicators (in particular, assembly parameters). Direct modeling of the conjugation process using numerical conjugation and finite-element models of assemblies requires significant computational resources and is often accompanied by problems convergence of solutions. In order to solve the above problems, it is possible to use neural network models describing the main regularities of the pai
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23

Itoh, S., S. Kubota, S. Nagano, and M. Fujita. "On Generation of Ultra-High Pressure by Converging of Underwater Shock Waves." Journal of Pressure Vessel Technology 120, no. 1 (1998): 51–55. http://dx.doi.org/10.1115/1.2841884.

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The characteristics of a new assembly for the shock consolidation of difficult-to-consolidate powders, such as inter-metallic compounds or ceramic materials, were investigated by both the experimental method and numerical simulation method. The assembly consists of an explosive container, a water chamber, and a powder container. Once the explosive is detonated, a detonation wave occurs and propagates, and then impinges on the water surface of the water chamber. After that, there occurs immediately an underwater shock wave in the water chamber. The underwater shock wave interacts with the wall
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24

Il’inykh, Viktor. "Evaluation of quality parameters of conical profile compounds in nodes of multi-purpose machines." E3S Web of Conferences 140 (2019): 02003. http://dx.doi.org/10.1051/e3sconf/201914002003.

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The article presents a study of the mandrel spindle assembly for accuracy, contact stiffness and strength. The study was made on the basis of conical profile connections with an equiaxed contour. Experiments were carried out for multi-purpose machines of various layouts on the basis of the previously developed program-mathematical complex of evaluating the parameters of the shaft-sleeve coupling. The analysis of the simulation modeling results of the accuracy of the shaft (mandrel) installation in the hole of the sleeve (spindle) is carried out taking into account the error in shape, taper, th
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25

Ganser, B. K. "Assembly and Analysis of Conical Models for the HIV-1 Core." Science 283, no. 5398 (1999): 80–83. http://dx.doi.org/10.1126/science.283.5398.80.

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26

Mattei, Simone, Annica Flemming, Maria Anders-Össwein, Hans-Georg Kräusslich, John A. G. Briggs, and Barbara Müller. "RNA and Nucleocapsid Are Dispensable for Mature HIV-1 Capsid Assembly." Journal of Virology 89, no. 19 (2015): 9739–47. http://dx.doi.org/10.1128/jvi.00750-15.

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ABSTRACTHuman immunodeficiency virus type 1 (HIV-1) is released from infected cells in an immature, noninfectious form in which the structural polyprotein Gag is arranged in a hexameric lattice, forming an incomplete spherical shell. Maturation to the infectious form is mediated by the viral protease, which cleaves Gag at five sites, releasing the CA (capsid) protein, which forms a conical capsid encasing the condensed RNA genome. The pathway of this structural rearrangement is currently not understood, and it is unclear how cone assembly is initiated. RNA represents an integral structural com
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27

Inna, Vishtak. "INFLUENCE OF GEOMETRIC CHARACTERISTICS OF GAS BEARINGS ON THE DURABILITY OF HIGH-SPEED SPINDLE ASSEMBLIES." Vibrations in engineering and technology, no. 4(107) (December 23, 2022): 83–87. http://dx.doi.org/10.37128/2306-8744-2022-4-10.

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The processing accuracy and productivity of metal-cutting machines are largely determined by the initial characteristics of the spindle assembly, since it is the last link in the kinematic chain of the main drive. Therefore, high demands are placed on spindle assemblies to ensure high rotational accuracy, high speed, parametric reliability, etc. Since the movement of shaping is carried out by the spindle and spindle bearings, they make a decisive contribution to the initial characteristics of the spindle units. The installation of spindles on gas bearings makes it possible to significantly inc
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28

Pawar, Sanjay R., and Vikas M. Phalle. "Effect of wear on the performance of hole entry hybrid conical journal bearing employing constant flow valve compensation." Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology 233, no. 9 (2019): 1277–92. http://dx.doi.org/10.1177/1350650119838078.

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Hybrid bearings gets worn gradually during the start and stop operation. This wearing leads to change in the geometry of bearing and affects the radical clearance as well as fluid film thickness. Therefore, these discontinuities in the radial clearance can influence the performance characteristics. With the purpose of preventing irreparable failure state of bearing assembly, it is essential to concentrate on the actual changes in the performance parameters of hole entry hybrid conical journal bearing due to wear. In this context, the main aim of this analysis is to predict the performance of h
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29

Wu, S. H., and S. J. Tsai. "Geometrical design of skew conical involute gear drives in approximate line contact." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 223, no. 9 (2009): 2201–11. http://dx.doi.org/10.1243/09544062jmes1340.

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A novel design for skew conical involute gear drives in approximate line contact is proposed. Such a drive has a contact ellipse with a large major-to-minor-axis ratio, which allows it to overcome the weakness of conical gear drives for application in power transmission. This gearing design approach is characterized by reduced edge contact sensitivity and increased surface durability. The edge contact sensitivity that can arise with this kind of gear drive due to assembly or manufacturing errors is evaluated by analysing the value of the shift of the line of action caused by such errors. The s
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30

Santus, Ciro, L. Bertini, and M. Beghini. "Fretting Fatigue Apparatus for Shrink-Fitted Shaft Assembly." Applied Mechanics and Materials 7-8 (August 2007): 43–48. http://dx.doi.org/10.4028/www.scientific.net/amm.7-8.43.

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The present paper proposes a new test rig to perform fretting fatigue tests on a shrinkfitted shaft assembly. A shrink-fitted shaft is put under rotating bending by means of an eccentric offset at one end. The shaft is driven near to its first resonance condition to significantly reduce the required force to produce bending. Test parameters are the imposed bending stress amplitude, and the hub radial pressure obtained through conical fitting. The proposed apparatus allows for changing bending stress amplitude and hub pressure to generate fretting fatigue tests at different conditions. In parti
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31

Dehtiarov, Ivan, Anna Neshta, Mykola Samardak, Vitalii Kononovych, and Yaroslav Klok. "Analysis of geometric parameters and technical requirements for pin conical joints in pump nodes." Bulletin of the National Technical University «KhPI» Series: New solutions in modern technologies, no. 4 (10) (December 30, 2021): 24–35. http://dx.doi.org/10.20998/2413-4295.2021.04.04.

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The article analyzes the causes of the situation with the appearance of manufacturing errors and the lack of the necessary technical requirements to perform a pin conical joint his intended purpose. The analysis was performed based on geometric construction of the assembly dimensional chain of two parts to be connected and a conical pin with a taper 1:50 according to GOST 9465-79, which is used in the pin joints of pumping equipment. The geometric analysis included the separation of deviations into linear dimensions and angular deviations. The values of the angular deviations were reduced to t
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32

Мещеряков, Sergey Meshcheryakov, Романович, et al. "ASSEMBLY FOR GRINDING PRESSURE AND DISAGGREGATION PRESSED MATERIALS." Bulletin of Belgorod State Technological University named after. V. G. Shukhov 2, no. 1 (2016): 144–49. http://dx.doi.org/10.12737/24018.

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The article describes the design of a pilot plant PVI includes a feed hopper mounted on the frame of the conical rolls and designersusa device, which consists of additional rolls with a reverse taper rolls the main. allows to combine the processes of comminution and disaggregation of compressed materi-als. We theoretically studied the implementation of directional movement pressed into the plate material from the main to the additional rolls desagglomeration device. Presents an analysis of the graphic curves constructed according to the obtained equations for the linear size of the capture zon
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33

Ovejero, César A., Silvia A. González та José L. Affranchino. "The Conserved Tyr176/Leu177 Motif in the α-Helix 9 of the Feline Immunodeficiency Virus Capsid Protein Is Critical for Gag Particle Assembly". Viruses 11, № 9 (2019): 816. http://dx.doi.org/10.3390/v11090816.

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The capsid domain (CA) of the lentiviral Gag polyproteins has two distinct roles during virion morphogenesis. As a domain of Gag, it mediates the Gag–Gag interactions that drive immature particle assembly, whereas as a mature protein, it self-assembles into the conical core of the mature virion. Lentiviral CA proteins are composed of an N-terminal region with seven α-helices and a C-terminal domain (CA-CTD) formed by four α-helices. Structural studies performed in HIV-1 indicate that the CA-CTD helix 9 establishes homodimeric interactions that contribute to the formation of the hexameric Gag l
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34

Bedlaoui, Allal, and Hamid Boutoutaou. "Effect of form defect on pipe surfaces subjected to pressure at the assembly point." Advances in Mechanical Engineering 14, no. 7 (2022): 168781322211097. http://dx.doi.org/10.1177/16878132221109722.

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Shrink-fit assemblies have been used to offer a more robust running surface for wooden wheels for a long time. Generally, the two parts are cylindrical or conical. Shrink-fit is now an operation that involves creating contact between two cylinders, there is no third party, and this is good economically. It’s employed in a variety of industries, including automotive, aerospace, oil and gas, and train wheels. To do this operation, the inner cylinder’s outer radius must be greater than the outer cylinder’s inner radius, that difference between them is called “interference,” the latter is being im
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35

Abramov, I. V., F. F. Fattiev, D. M. Gurkov, S. V. Tanygin, and B. I. Korotkov. "Manufacture of conical joints for the assembly of sections of paper-making equipment." Chemical and Petroleum Engineering 22, no. 4 (1986): 146–47. http://dx.doi.org/10.1007/bf01149243.

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36

Arasu, S., and A. Krishnamoorthy. "Design and Manufacturing of Conical Vent Profile Disc Brake." Applied Mechanics and Materials 766-767 (June 2015): 1028–33. http://dx.doi.org/10.4028/www.scientific.net/amm.766-767.1028.

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Braking system is one amongst the foremost vital contact mechanisms in an automobile. The braking potency in automobile depends on the desertion characteristics of the constraint assembly. The heat refusal from the system is proportional to the desertion of brake. This paper aims to bring out producing, testing of conical shape vent profile and studies of existing cooling vent profile heat refusal throughout the braking. This result reduces the thermal and structural stress on the brake plate. The prevailing vehicles brakes has been made from cylindrical vent profiles that in theory has lesser
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37

Yoon, Joonsik, Minjoo Noh, Jun Bae Lee, and Jun Hyup Lee. "Highly Sustainable and Completely Amorphous Hierarchical Ceramide Microcapsules for Potential Epidermal Barrier." Polymers 12, no. 9 (2020): 2166. http://dx.doi.org/10.3390/polym12092166.

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As a main component of the stratum corneum, ceramides can construct protective lamellae to provide an epidermal barrier against dehydration or external microorganisms. However, as ceramide molecules can easily form the isolated crystalline phase through self-assembly due to the amphipathic nature of bioactive lipids, the effective incorporation of ceramides into liquid media is the remaining issue for controlled release. Here, we report an unprecedented effective strategy to fabricate a completely amorphous and highly sustainable hierarchical ceramide polymer microcapsule for promising epiderm
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38

Bołoz, Łukasz. "Directions for increasing conical picks’ durability." New Trends in Production Engineering 2, no. 1 (2019): 277–86. http://dx.doi.org/10.2478/ntpe-2019-0029.

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Abstract Conical picks are cutting tools used in many branches, in particular in the mining, road construction and building branch. Contact with the excavated face causes their constant wear, which is an unfavorable but unavoidable process. Milling heads of working machines are equipped with several dozen conical picks, and mining in abrasive or hardly accessible rocks can reduce their life to a few hours. It is in the interest of both users and producers to increase their durability, as tools replacement, apart from purchase and logistic costs, results in machine downtimes. In the article var
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39

Ilyinykh, V. A. "Application of conical profile spindle-mandrel joints in multi-purpose machines." Omsk Scientific Bulletin, no. 175 (2021): 12–16. http://dx.doi.org/10.25206/1813-8225-2021-175-12-16.

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The article deals with the solution of the problem of improving the quality of torque transmission connections of spindle units of multi-purpose machines. The aim of the work is to determine the contact stiffness of the spindle-mandrel joints of various types, based on the conducted simulation experiments of the assembly and disassembly process of auxiliary tools of various structural forms, in conditions of reusable replacements. A comparative analysis of the mathematical expectations of contact stiffness of traditional and non-traditional conical profile split joints based on an equiaxial co
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40

Zakarlyukin, S. I., and G. I. Koval'. "New technologies of radial forging of pipe on a mandrel in hot and cold condition." Ferrous Metallurgy. Bulletin of Scientific , Technical and Economic Information 81, no. 5 (2025): 42–49. https://doi.org/10.32339/0135-5910-2025-5-42-49.

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Based on the analysis of known and our own experience, the expediency of using radial forging to produce short pipes on a conical mandrel made of special steels in a hot state is shown. It is noted that producing pipes by radial forging on a mandrel in a hot state is of practical interest only in the production of pipes with a diameter of more than 200 mm with an average wall thickness and thick-walled.The experimental technology of radial forging of short pipes of heat-resistant alloys KhN45Yu and KhN38VT on a fixed conical mandrel, developed and implemented on the SKK-14 RKM, is described.Th
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Zhong, Yu-Wu, Yutaka Matsuo, and Eiichi Nakamura. "Lamellar Assembly of Conical Molecules Possessing a Fullerene Apex in Crystals and Liquid Crystals." Journal of the American Chemical Society 129, no. 11 (2007): 3052–53. http://dx.doi.org/10.1021/ja068780k.

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42

Harvey, James E. "Image degradation due to assembly and alignment errors in conical foil x‐ray telescopes." Optical Engineering 35, no. 10 (1996): 3037. http://dx.doi.org/10.1117/1.600954.

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43

Okulov, R. A., V. A. Krashaninin, B. R. Gelchinsky, and A. A. Rempel. "Influence of the shape of the anode assembly inner channel on plasma flow velocity." Uchenye Zapiski Kazanskogo Universiteta. Seriya Fiziko-Matematicheskie Nauki 166, no. 1 (2024): 58–73. http://dx.doi.org/10.26907/2541-7746.2024.1.58-73.

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This article considers how the shape of the inner channel in the anode assembly affects plasma flow velocity in a plasma torch. Three different shapes of the anode assembly were analyzed, all with a conical confusor part of 50 mm in length: with a diameter transition from 12 to 6 mm, from 12 to 8 mm, and from 12 to 10 mm. A computer experiment was performed using the finite element method and then validated by the subsequent full-scale experiment on a laboratory plasma unit. The obtained results were verified. The verification outcomes showed a satisfactory convergence and were consistent with
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44

Yang, Hsueh-Cheng, and Chih-Yao Sun. "Using a planar rack cutter with variable modulus to generate a spherical gear pair." Transactions of the Canadian Society for Mechanical Engineering 44, no. 1 (2020): 108–20. http://dx.doi.org/10.1139/tcsme-2018-0265.

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In this study, an imaginary planar rack cutter with variable modulus and discrete conical teeth was used to generate a spherical gear pair with double degree of freedom. First, a geometric method was used to design the mathematical model of the imaginary planar rack cutter with variable modulus and discrete conical teeth. Next, the relationship of coordinate systems between the generating and generated surfaces was established. Then, the family of the imaginary planar rack cutter surfaces was obtained by homogeneous coordinate transformation matrix. Further, two equations of meshing between th
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45

Radermacher, M., V. Rao, R. Grassucci, et al. "Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle." Journal of Cell Biology 127, no. 2 (1994): 411–23. http://dx.doi.org/10.1083/jcb.127.2.411.

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The calcium release channel (CRC) from skeletal muscle is an unusually large tetrameric ion channel of the sarcoplasmic reticulum, and it is a major component of the triad junction, the site of excitation contraction coupling. The three-dimensional architecture of the CRC was determined from a random conical tilt series of images extracted from electron micrographs of isolated detergent-solubilized channels prepared in a frozen-hydrated state. Three major classes of fourfold symmetric images were identified, and three-dimensional reconstructions were determined for two of these. The two indepe
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Bałdowska-Witos, Patrycja, Marek Macko, Daniel Łączny, Weronika Kruszelnicka, and Jakub Lewandowski. "Computer-aided Eco-design Grinding Machines using Software SolidWorks Sustainability." MATEC Web of Conferences 357 (2022): 02022. http://dx.doi.org/10.1051/matecconf/202235702022.

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The publication presents selected results of an attempt to link material and environmental valuation with the design of technical objects in accordance with the requirements of the concept of Life Cycle Management. The goal of this action was to develop environmental analysis of the conical shredder using the SolidWorks Sustainability application. The assessment of environmental impacts included: extraction of raw materials, material processing, production of parts, assembly, use of the product, landfill storage and transport. Based on the results of the analysis, the potential emission levels
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Sofiienko, Andrii, Chad Jarvis, and Ådne Voll. "Monte Carlo Simulations of a Scanning System Based on a Panoramic X-Ray Tube with a Conical Anode." Physics Research International 2014 (August 21, 2014): 1–9. http://dx.doi.org/10.1155/2014/847651.

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Monte Carlo simulations were used to study photon production in a panoramic X-ray tube with a conical tungsten target to determine the optimal characteristics of the target shape and electron beam configuration. Several simulations were performed for accelerating potentials equal to 250 kV, 300 kV, and 500 kV with electron beams of various radii and anode sizes. The angular distribution of the photon intensity was analysed by numerical calculations for an assembly composed of an X-ray tube and an external collimator with a cylindrical hole to simulate a panoramic scanning system with an X-ray
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Kadam, Sanket Shankar, N. M. Virupakshappa, and U. Achutha Kini. "Root cause analysis of rough conical seat grinding problem in fuel pump cylinder head by Shainin methodology." MATEC Web of Conferences 144 (2018): 05009. http://dx.doi.org/10.1051/matecconf/201814405009.

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Problem solving plays a major role in quality engineering and it is popularly adopted by manufacturing industry. This study is aimed to determine root cause for rejection of cylinder head due to rough conical grinding problem by Shainin method. This has two major parts, first is diagnostic part which involves finding out the root cause and second is a remedial action part which consist of actual application of findings to rule out the problem. Wear in tool holder assembly is identified as root cause for rough grinding problem. Converging to root cause and validating the same achieved by succes
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Li, Xin, Yongkang Jiang, Yaoyao Wei, et al. "The Effect of Different Substances Embedded in Fullerene Cavity on Surfactant Self-Assembly Behavior through Molecular Dynamics Simulation." Molecules 29, no. 10 (2024): 2355. http://dx.doi.org/10.3390/molecules29102355.

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Fullerene-based amphiphiles are new types of monomers that form self-assemblies with profound applications. The conical fullerene amphiphiles (CFAs) have attracted attention for their uniquely self-assembled structures and have opened up a new field for amphiphile research. The CFAs and CFAs with different substances embedded in cavities are designed and their self-assembly behaviors are investigated using molecular dynamics (MD) simulations. The surface and internal structures of the micelles are analyzed from various perspectives, including micelle size, shape, and solvent-accessible surface
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Accola, Molly A., Stefan Höglund та Heinrich G. Göttlinger. "A Putative α-Helical Structure Which Overlaps the Capsid-p2 Boundary in the Human Immunodeficiency Virus Type 1 Gag Precursor Is Crucial for Viral Particle Assembly". Journal of Virology 72, № 3 (1998): 2072–78. http://dx.doi.org/10.1128/jvi.72.3.2072-2078.1998.

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ABSTRACT The capsid (CA) and nucleocapsid domains of the human immunodeficiency virus type 1 Gag polyprotein are separated by the p2 spacer peptide, which is essential for virus replication. Previous studies have revealed that p2 has an important role in virus morphogenesis. In this paper, we show that a crucial assembly determinant maps to the highly conserved N terminus of p2, which is predicted to form part of an α-helix that begins in CA. A mutational analysis indicates that the ability of the N terminus of p2 to adopt an α-helical structure is essential for its function during virus assem
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