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Dissertations / Theses on the topic 'Conjunctival'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Ellingham, Roger Bruce. "Human conjunctival mucins." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310590.

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2

Owen, Christopher Grant. "Quantitative analysis of conjunctival vasculature." Thesis, Queen's University Belfast, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287628.

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3

Schrader, S. "Tissue engineering for conjunctival reconstruction." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1348133/.

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Reconstruction of the conjunctiva is an essential part of ocular surface regeneration, especially if an extensive area or the whole ocular surface is affected, such as in patients with ocular cicatricial pemphigoid, Stevens- Johnson syndrome or chemical/thermal burns. However, there is a lack of suitable donor tissue for conjunctival replacement, especially when large grafts are required and it is important that new materials and methods are developed for conjunctival reconstruction. The aims of this thesis were; to characterise the conjunctival epithelial cell population and to improve the ma

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4

Zhan, Hong. "The immunological role of conjunctival epithelial cells." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405640.

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5

Lawrenson, John Gerard. "Corpuscular nerve endings in the human conjunctiva : relationship to conjunctival touch sensitivity and sensitivity changes in contact lens wear." Thesis, City University London, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304643.

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6

Zhang, Yi 1956. "Intermediate filaments : the prognostic marker for conjunctival melanomas." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33456.

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Intermediate filaments (IFs) are highly regulated and conserved during cell transformation and tumor development. The co-expression of keratin 8, 18 and vimentin has been shown to be related to recurrence and metastasis in both cutaneous and uveal melanomas. This thesis provides the first immunohistochemical evidence that the co-expression of keratin 8, 18 and vimentin is present in one third of conjunctival melanomas. The results show that conjunctival melanomas co-expressing IFs are mixed cell tumors with diffuse growth patterns. It is also shown that melanoma cells co-expressing IFs are mai

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7

Faal, Nkoyo Inyang. "Conjunctival immune responses in human ocular chlamydial infections." Thesis, Open University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.543853.

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8

Crowston, Jonathan Guy. "Antimetabolite induced fibroblast apoptosis in conjunctival wound healing." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393162.

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9

Wong, Tina Tzee Ling. "The role of matrix metalloproteinases in conjunctival wound healing." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405196.

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10

Ihmed, Shamsa. "Identification of specific genetic changes associated with conjunctival melanoma." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/21235/.

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Conjunctival melanoma (ConM) are rare ocular tumours but the incidence, like that of cutaneous melanoma (CM), is increasing and sunlight exposure is considered to be a factor in their development. Little is known about the genetic changes that are associated with this malignancy. Previous studies have reported that ConMs have mutations of the BRAF and NRAS genes and recently, the TERT promoter has also been shown to be commonly mutated in the ConM form. The genetic classification of ocular melanomas, however, has shown itself to be highly reliable in determining the prognosis of patients with

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11

Makuloluwa, Aruni Kumari. "Development of a synthetic substrate for conjunctival cell transplantation." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3009446/.

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The conjunctiva is a translucent mucous membrane consisting of epithelial cells and goblet cells (GCs). It protects the eye from external insults and prevents desiccation of the ocular surface by producing mucins of the tear film. Severe scarring due to injuries and diseases could lead to its anatomical and functional impairment. Moreover, the success of a limbal or a corneal transplant is dependent on the presence of a healthy ocular surface and a tear film. Various grafts and substrates employed to replace the damaged conjunctiva to date, have advantages and disadvantages peculiar to the mat

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12

Holguin, Colorado Luisa Fernanda. "Impact of contact lens wear on conjunctival goblet cells." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/98118/1/Luisa%20Fernanda_Holguin%20Colorado_Thesis.pdf.

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Up to fifty percent of contact lens wearers discontinue from lens wear as a result of symptoms of dry eye. Using a high power confocal microscope specially adapted for examining the eye, the candidate observed that contact lens wear is associated with a reduction in the number of mucus-secreting conjunctival goblet cells, which means that the eye is less well lubricated, leading to discomfort during blinking. This discovery may pave the way towards developing strategies to avoid lens-induced discomfort, leading to more satisfied patients and saving the contact lens industry hundreds of million

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13

Dale, S. "Aldehyde dehydrogenase as a novel and potential therapy for conjunctival fibrosis." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1433170/.

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Fibroproliferative diseases including pulmonary fibrosis and scleroderma are leading causes of mortality. Mucous membrane pemphigoid (MMP) is a systemic autoimmune disease characterised by inflammation and variable blistering and scarring of one or more of the mucous membranes and the skin. MMP affecting the conjunctiva was formally termed Ocular Cicatricial Pemphigoid (OCP). Ocular MMP (OcMMP) will be used in this thesis to describe studies carried out on MMP patients having ocular involvement as a major component of their disease. Therefore OcMMP is synonymous with the term OCP used in previ

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14

Mhlanga, Gugulethu. "Aesthetic outcomes using trans-conjunctival vs transcutaneous approaches for orbital trauma." University of the Western Cape, 2021. http://hdl.handle.net/11394/7745.

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Magister Chirurgiae Dentium - MChD<br>Introduction: Maxillofacial and oral surgeons often encounter challenges when choos-ing an appropriate surgical access for patients who sustained periorbital and orbital trauma. There are various surgical approaches/incisions (transcutaneous and transcon-junctival) used to access the periorbital skeletal framework. However, there is no consen-sus in the literature regarding the aesthetical outcome of these approaches/incisions. Complications of the lower lid such as entropion, ectropion, retraction of lower lid, scar-ring, oedema of lid, canthal mal-positi

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15

Kasbekar, S. "Development of substrates for the ex vivo expansion of conjunctival epithelium." Thesis, University of Liverpool, 2016. http://livrepository.liverpool.ac.uk/3003169/.

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The conjunctiva is a mucous membrane lining the ocular surface and is crucial to ocular surface homeostasis. Ocular surface diseases lead to a poor tear film, irreversible conjunctival scarring and continual corneal desiccation that may result in painful loss of vision. Conjunctival integrity and a tear film with appropriate consituents are crucial to the survival of corneal and limbal stem cell transplants. I hypothesised that two novel substrates could be developed for the ex vivo expansion of conjunctival epithelium to address a range of transplantation requirements: 1) a degradable biologi

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16

Nihan, Laura. "Conjunctival Impression Cytology Assessment of Vitamin A Status of Migrant Children." DigitalCommons@USU, 1995. https://digitalcommons.usu.edu/etd/5437.

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Subclinical vitamin A deficiency was assessed in 65 Hispanic children attending four migrant Head Start programs in Utah. Subjects aged 2 to 6 years (median 3 years 10 months) were examined for evidence of vitamin A deficiency by conjunctival impression cytology. Biochemical indices for serum vitamin A, retinol-binding protein, zinc, and iron were performed. Of eight children (12.5%) with subclinical vitamin A deficiency, one child had a marginal serum vitamin A of 11 μg/dl. Retinol-binding protein concentrations were significantly lower in two subjects with abnormal conjunctival impression cy

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17

Sagga, Nada A. "Dynamics of limbal and conjunctival stem cell activity during ocular surface maintenance." Thesis, University of Aberdeen, 2017. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=235418.

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Corneal degenerative diseases and opacity are leading causes of corneal impairment and blindness worldwide. Like many epithelial tissues, the constant renewal of transparent corneal epithelial cells is essential for a lifelong healthy cornea and optimal vision. The limbus (the boundary between the cornea and the conjunctiva) is believed to be the site that harbours adult stem cells responsible for corneal maintenance and repair after injury, referred to as limbal epithelial stem cells (LESCs). In the basal limbal epithelium, an active LESC subset divides to yield progenitor cells that migrate

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18

Offiah, I. "Cross-talk between human T cells, mast cells and conjunctival epithelial cells." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1348498/.

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The ocular surface is continually exposed to the outside environment and is a common site of inflammation. Conjunctival epithelial cells are thought to play a role in innate responses at the ocular surface. The hypothesis of my study is that conjunctival epithelial cells also contribute to T cell and mast cell effector mechanisms in chronic allergic eye disease via secretion of cytokines. In this study we initially demonstrate that the conjunctiva expresses TLRs, and that the TLR3 ligand (poly I:C) activates conjunctival epithelial cells in vitro to secrete inflammatory mediators as part of th

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19

Hughes, James L. "The conjunctival epithelium and grass pollen allergen associated interactions in atopic eye disease." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439374.

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20

Kenawy, N. "Conjunctival melanoma : a multicentre study correlating baseline clinical features with histology and genetics." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3009316/.

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21

Saw, V. P. J. "The role of inflammation and fibroblasts in conjunctival scarring in ocular mucous membrane pemphigoid." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/18576/.

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Ocular mucous membrane pemphigoid (ocular MMP) is a visually devastating disease where up to 30% of patients become blind due to the consequences of conjunctival inflammation and aggressive fibrosis. Standard systemic immunosuppression controls inflammation, but is limited by toxicity. How well immunosuppressive therapy prevents fibrosis is unknown. The cellular and molecular mechanisms that lead to excessive conjunctival fibrosis in ocular MMP are incompletely understood. Chronic inflammation and repair play an important role, but the conjunctival fibroblasts may also be autonomously activate

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22

Wessels, William Louis Fick. "Reconstruction of the lower eye lid with a rotation-advancement tarso-conjunctival cheek flap." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5441.

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Thesis (MMed (Surgical Sciences. Plastic and Reconstructive Surgery))--University of Stellenbosch, 2010.<br>The repair of full-thickness defects of the lower eyelids poses a challenge because a graft in combination with a flap is typically used to replace either the posterior or anterior lamella. This often results in aesthetically and functional unsatisfactory outcomes. A rotation-advancement tarso-conjunctival cheek flap, which reconstructs both posterior and anterior lamella with vascularized tissue similar to the native eyelid, is described. Nine patients underwent reconstruction wi

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23

Cronelöv, Mathilda. "Förekomst av corneal och conjunctival hyperfluorescens associerad till skötselprodukter i kombination med kontaktlinsen Biofinity." Thesis, Linnéuniversitetet, Institutionen för medicin och optometri (MEO), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-65556.

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Syfte: Syftet med denna studie var att undersöka om preservative-associated transient hyperfluorescens (PATH) förekommer mer vid användandet av en multipurposevätska kontra vid användandet av ett kontaktlinsskötselsystem med väteperoxid. Metod: Försökspersonerna, vana kontaktlinsbärare och ögonfriska, tillpassades den mjuka kontaktlinsen Biofinity. Gradering av ögats främre segment utfördes med och utan infärgning av fluorescein. Därefter fick försökspersonerna två olika kontaktlinsvätskor, Refine One Step och BioTrue, att använda som skötselsystem. Lott drogs för att bestämma vilken lins som

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24

Mead, Anna Louise. "Modulation of transforming growth factor beta (TGF beta) and conjunctival scarring after glaucoma filtration surgery." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1444824/.

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The conjunctival wound healing response remains the major barrier to achieving long term intraocular pressure control after glaucoma filtration surgery (GFS). Current anti-scarring agents improve the outcome of surgery but act by causing widespread cell death and can be associated with potentially blinding complications. In addition, some individuals still fail surgery. A more physiological and targeted approach to wound healing control and scarring prevention is required. Of all the growth factors, TGF beta has been shown to play a pivotal role in wound healing throughout the body, and has be

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25

Earley, Olivia. "Morphology and in vivo growth dynamics of the human conjunctival epithelium : an age-related study." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317530.

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26

Yu, Wai Man C. Y. O. L. "Targeting the Myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway in conjunctival fibrosis." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1559574/.

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Glaucoma is the leading cause of irreversible blindness and its prevalence is estimated to reach 79.6 million people by 2020. Wound contraction and scarring are the principal causes of blockage of aqueous flow at the drainage site in glaucoma filtration surgery. The cytotoxic antimetabolites, mitomycin-C and 5-fluorouracil, are widely used but have potentially blinding complications. There is thus a large unmet need for alternative agents with more targeted physiological effects and less cytotoxicity. The myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway is a mast

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27

Bhattacharya, Dhruva, Li Yu, and Mingwu Wang. "Expression patterns of conjunctival mucin 5AC and aquaporin 5 in response to acute dry eye stress." PUBLIC LIBRARY SCIENCE, 2017. http://hdl.handle.net/10150/626191.

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The relationship between aquaporin (AQP) 5 and mucin (MUC) 5AC in the conjunctiva was investigated in response to acute dry eye (DE) stress. A mixed-mechanism rabbit DE model, in which the main lacrimal gland, Harderian gland, and nictitating membrane were resected, was further explored in this study. Conjunctival impression cytology specimens were harvested before excision (BE) and up to 3 months after excision (AE) in 8 (16 eyes) male New Zealand White rabbits, and immunoblotting was employed to assess the expression of AQP5 and MUC5AC. It was observed that AQP5 and MUC5AC showed a positive,

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28

Ramsey, Alison C. "Defining the conjunctival staining method : instillation volume and time course to assess staining with lissamine green." Thesis, NSUWorks, 2008. https://nsuworks.nova.edu/hpd_opt_stuetd/4.

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A thesis presented by Alison C. Ramsey, OD submitted to the Clinical Vision Research Program, College of Optometry of Nova Southeastern University in partial fulfillment of the requirements for the degree of Master of Science.

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29

Cordeiro, Maria Francesca. "The role of Transforming Growth Factor-#beta# in the conjunctival wound healing process following glaucoma filtration surgery." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287899.

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30

Agaba, Charles Ateenyi. "Human papillomaviruses and their association with squamous cell carcinoma of the conjunctiva." Stockholm : Kampala : Karolinska Institutet ; Makerere University, 2009. http://diss.kib.ki.se/2009/978-91-7409-599-9/.

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31

Chang, Lydia Pei-Yu. "Fibroblast interferon beta mediated prevention of T cell apoptosis : its relationship with the development of excessive conjunctival scarring." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268345.

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32

Cruzado-Sanchez, Deivy, Walter Andree Tellez, Beltran Villarreal-Aguilar, et al. "Conjunctival squamous cell carcinoma: Prognostic factors for the recurrence and metastasis and clinicopathological characteristics at an oncological hospital in Peru." BMJ Publishing Group, 2020. http://hdl.handle.net/10757/654909.

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Background/aims Conjunctival squamous cell carcinoma (CSCC) is the most frequent malignant tumour of the conjunctiva, with scarce recurrence and infrequent metastasis. The purpose of this study is to describe the clinical and pathological characteristics of this neoplasm and to identify the prognostic factors for recurrence and metastasis in a cancer hospital in Peru. Materials and method A longitudinal, retrospective study of 176 consecutive patients diagnosed with SCC of the conjunctiva. Sociodemographic and clinical characteristics were evaluated. In addition, Kaplan-Meier curves were perfo

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33

Albietz, Julie M. "The conjunctiva in dry eye: Histological changes, inflammation, topical treatments, contact lenses and refractive surgery." Thesis, Queensland University of Technology, 1999. https://eprints.qut.edu.au/36745/1/36745_Digitised%20Thesis.pdf.

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The aim of this research is to investigate the histological and inflammatory conjunctiva! ocular surface changes occurring in dry eye. It is anticipated that by enhancing the understanding of the components of ocular surface damage in dry eye, clinicians diagnosing and managing dry eye will be able to more specifically and effectively manage this chronic and often debilitating condition. A review of the literature indicated that traditional dry eye diagnosis and treatment has focused primarily on conditions involving aqueous tear deficiency and its autoimmune form, Sjogren's syndrome. In re

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34

Eulitz, Theresa P. "Untersuchungen zum Verlauf des konjunktivalen Status bei Hunden unter Bedingungen eines stationären Aufenthaltes." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-68355.

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35

Pereira, Vanessa Figueredo. "Uso de suabe conjuntival na detecção de Leishmaniose Visceral Canina por PCR." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-12082013-162729/.

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A leishmaniose visceral canina é uma zoonose, no Brasil causado pelo protozoário Leishmania chagasi (syn. L. infantum). É endêmica em 88 países, os quais compreendem regiões tropicais e subtropicais do Velho e do Novo Mundo, com incidência estimada em 2 milhões de casos por ano. No ambiente urbano, o cão doméstico é considerado o principal reservatório do parasito. A transmissão da doença ocorre através da picada do vetor, díptero flebotomíneo, da espécie Lutzomyia longipalpis. O diagnóstico pode ser feito através de métodos diretos, como esfregaço preparado com os diferentes órgãos linfoides,

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36

Benvenga, Graziella Ulbricht. "Ocorrência de Leishmania spp. em cães, gatos e equinos no Estado de São Paulo." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-06022014-084920/.

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Cães, gatos e equinos domésticos podem ser importantes reservatórios de agentes infecciosos potencialmente zoonóticos, podendo-se destacar entre eles as leishmanioses. Por esse motivo, torna-se necessário aprimorar o conhecimento sobre essas enfermidades, estudando mais detalhadamente sua ecoepidemiologia, importante fonte de informações para a tomada de decisões com relação ao controle das mesmas. O presente estudo objetivou verificar a ocorrência de Leishmania spp. em cães, gatos e equinos procedentes de regiões endêmicas e não endêmicas do estado de São Paulo, por meio dos testes diagnóstic

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37

Khajavi, Noushafarin [Verfasser]. "Analysis of expression and function of thermo-sensitive transient receptor potential channels in cultivated human conjunctival epithelial and human uveal melanoma cells / Noushafarin Khajavi." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2015. http://d-nb.info/1075757541/34.

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38

Rodrigues, Manuel. "Génétique des mélanomes oculaires." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS107.

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Les mélanomes oculaires sont des tumeurs rares représentant environ 5% des mélanomes. Les mélanomes oculaires peuvent provenir de deux tissus : l’uvée (~500 cas/an en France) et la conjonctive (~30 cas/an). Les mélanomes uvéaux présentent un très faible taux de mutations somatiques. Ces tumeurs sont également porteuses d’altérations du nombre de copies caractéristiques (gains du 8q, 1q, 6p, pertes du 3, du 1p, du 6q ou du 8p). L’évolution du génome de ces tumeurs durant la progression métastatique est à ce jour mal décrit. Afin d’explorer l’évolution métastatique du mélanome uvéal, nous avons

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39

Aguirre-Romo, Israel. "Comparison of Conjunctival Application of Topical 0.5 % Levofloxacin and 1% Povidone-Iodine Flushing versus Povidone-Iodine alone in Patients undergoing Intraocular Surgery: A Prospective Randomized Study." Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-60145.

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40

Mergler, Stefan [Verfasser]. "Functional expression of temperature-sensitive transient receptor potential channels (TRPs) in cultured human corneal and conjunctival cells : Relevance in the pathophysiology of ocular surface diseases / Stefan Mergler." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2015. http://d-nb.info/1078505403/34.

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41

Benassi, Julia Cristina. "Detecção de Leishmania spp. por PCR em tempo real em amostras de suabe conjuntival de cães, gatos e equinos." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/74/74135/tde-13102015-151435/.

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O objetivo do presente estudo foi detectar Leishmania spp. pela PCR em tempo real (qPCR) em amostras de DNA extraído de sangue e suabe conjuntival de cães, gatos e equinos. E também, verificar a positividade dessas amostras pela PCR convencional (cPCR), utilizando oligonucleotídeos específicos para L. infantum (inf.cPCR). Para isso, amostras de sangue e suabe conjuntival de 204 cães, 108 gatos e 54 equinos saudáveis foram testadas pela qPCR para Leishmania spp. e os resultados comparados pelo índice kappa a resultados de cPCR para Leishmania spp. (ssp.cPCR) previamente obtidos. A qPCR de sangu

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42

Pereira, Vanessa Figueredo. "Identificação e caracterização de tripanossomatídeos que infectam cães em área endêmica para leishmaniose visceral canina." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-20032017-161042/.

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A leishmaniose visceral canina (LVC) é uma grave zoonose, causada pela Leishmania infantum (syn. chagasi). O ciclo deste parasito é heteroxeno e a transmissão acontece principalmente pela picada da fêmea do vetor, dípteros da espécie Lutzomyia longipapis. O cão doméstico é o principal alvo das campanhas de controle da doença por ser a principal fonte de infecção para o vetor no ambiente urbano. O Ministério da Saúde adota testes sorológicos para a detecção de animais positivos; no entanto a sensibilidade e especificidade desses testes são questionáveis. Além das falhas inerentes a qualquer tes

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43

Gomes, Patrícia Inês Santos. "Deteção da infeção por Leishmania spp., em gatos da Área Metropolitana de Lisboa, através de técnicas de diagnóstico serológico (IFI e ELISA) e de uma técnica molecular (qPCR) aplicada a células conjuntivais e a sangue." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2015. http://hdl.handle.net/10400.5/8485.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A leishmaniose visceral zoonótica é uma doença endémica em Portugal e é causada pelo protozoário Leishmania infantum. O cão é o principal hospedeiro reservatório natural, contudo o gato (Felis catus domesticus) tem revelado uma importância crescente na epidemiologia da doença. Nesta dissertação foi realizado um rastreio epidemiológico da infeção por Leishmania spp. em 47 animais, 32 deles com dono e 15 provenientes de um gatil, na Área Metropolitana de Lisboa (AML), utilizando duas técnicas serológicas, para pesquisa de anticorpos a

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44

Bhattacharya, Pradipta. "The corneal epithelium in health and disease." Thesis, Queensland University of Technology, 2022.

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The cornea is the anterior transparent layer of the eye, and understanding corneal epithelial morphology is valuable in monitoring ocular surface diseases. A meta-analysis showed that central corneal basal cell density and nerve parameters were reduced in diseases affecting the ocular surface including limbal stem cell deficiency. Using newly developed image analysis techniques it was observed that epithelial cell density was highest at the corneal nerve whorl region. A decrease in epithelial cell density was observed in eyes with conjunctival ultraviolet autofluorescence, i.e. with sunlight-i

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45

Sessa, Mariana. "Testes diagnósticos oftalmológicos em sagui de tufo preto (Callithrix penicillata)." Botucatu, 2020. http://hdl.handle.net/11449/192772.

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Orientador: Cláudia Valéria Seullner Brandão<br>Resumo: O estudo objetivou descrever valores de referência para importantes testes diagnósticos oftalmológicos, como sensibilidade corneal, produção lacrimal, pressão intraocular, espessura corneal e microbiota conjuntival em saguis de tufo preto (Callithrix penicillata) saudáveis e sem alterações oculares. Foram utilizados 13 saguis de tufo preto, totalizando 26 olhos, provenientes do CEMPAS da Faculdade de Medicina Veterinária e Zootecnia - UNESP, Botucatu, São Paulo, Brasil. Os saguis foram submetidos a contenção química com anestesia dissocia

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Rico, Ana Sofia Moreira Vaz. "Os testes de provocação conjuntival na avaliação da eficácia da imunoterapia alergénio-específica rush na dermatite atópica canina." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2014. http://hdl.handle.net/10400.5/7004.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A atopia é uma doença frequente no cão, mas pouco se sabe acerca do envolvimento ocular, desconhecendo-se a prevalência e o impacto da conjuntivite alérgica (CA) na dermatite atópica canina (DAc). O teste de provocação conjuntival (TPC) é um modelo útil ao seu estudo, sendo utilizado na avaliação da eficácia de várias formas de tratamento, incluindo a imunoterapia alergénio-específica (ITAE). Através da realização de TPC em pacientes atópicos com sensibilização a Dermatophagoides farinae (Df) pretendeu-se avaliar a contribuição deste

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Cassagne, Myriam. "Etude physiopathologique des complications oculaires observées chez des patients atteints de dermatite atopique traitée par Dupilumab." Electronic Thesis or Diss., Toulouse 3, 2023. http://www.theses.fr/2023TOU30288.

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Le dupilumab a prouvé son efficacité dans le traitement de la dermatite atopique (DA) modérée à sévère. Cependant, la survenue d'événements indésirables oculaires (Ocular Adverse Events, OAE) a été rapporté. Les objectifs de ce travail étaient de décrire l'incidence et la nature des OAE induits par le dupilumab, d'évaluer les facteurs prédisposants potentiels et d'en comprendre les bases moléculaires. Nous avons mené une première étude monocentrique, prospective, en vie réelle, chez des patients adultes atteints de DA traités par dupilumab, qui ont été systématiquement examinés par un ophtalmo

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Amor, Daniela Marreiros da Palma. "Etiologia das conjuntivites felinas e abordagem ao seu diagnóstico." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2014. http://hdl.handle.net/10400.5/7778.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A conjuntivite é uma doença ocular frequente no gato. A maioria das conjuntivites são infecções primárias causadas particularmente pelo herpesvírus felino-1 (HVF-1) e pela Chlamydophila felis (C. felis). Outros microrganismos envolvidos incluem o Mycoplasma felis (M. felis) e o calicivírus felino (CVF). O objectivo deste estudo retrospectivo é contribuir para a caracterização das conjuntivites felinas na população em estudo, estudando os principais agentes patogénicos da conjuntiva, o HVF-1, a C. felis, o M. felis e o CVF. Foram ana

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Al, Dossari Munira. "Confocal microscopic examination of the conjunctiva." Thesis, Queensland University of Technology, 2008. https://eprints.qut.edu.au/18316/1/Munira_Al_Dossari_Thesis.pdf.

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This project has provided a better understanding of the human conjunctiva, the glistening tissue covering the white of the eye, at the cellular level. The observations of this study may serve as a useful marker against which changes in conjunctival tissue due to disease, surgery, drug therapy or contact lens wear can be assessed. Laser scanning confocal microscopy was used to observe and measure characteristics the conjunctiva of healthy human volunteer subjects. It was concluded that this technique is a powerful tool for studying the human conjunctiva and assessing key aspects of the struct

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Al, Dossari Munira. "Confocal microscopic examination of the conjunctiva." Queensland University of Technology, 2008. http://eprints.qut.edu.au/18316/.

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This project has provided a better understanding of the human conjunctiva, the glistening tissue covering the white of the eye, at the cellular level. The observations of this study may serve as a useful marker against which changes in conjunctival tissue due to disease, surgery, drug therapy or contact lens wear can be assessed. Laser scanning confocal microscopy was used to observe and measure characteristics the conjunctiva of healthy human volunteer subjects. It was concluded that this technique is a powerful tool for studying the human conjunctiva and assessing key aspects of the struct

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