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Dissertations / Theses on the topic 'Conscious synthesis of development'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Gamez, David. "The development and analysis of conscious machines." Thesis, University of Essex, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494357.

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2

Carlstedt-Duke, Edward, and Erik Elfström. "Towards guidelines for development of energy conscious software." Thesis, Linköping University, Department of Computer and Information Science, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-17444.

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<p>In recent years, the drive for ever increasing energy efficiency has intensified. The main driving forces behind this development are the increased innovation and adoption of mobile battery powered devices, increasing energy costs, environmental concerns, and strive for denser systems.</p><p>This work is meant to serve as a foundation for exploration of energy conscious software. We present an overview of previous work and a background to energy concerns from a software perspective. In addition, we describe and test a few methods for decreasing energy consumption with emphasis on using soft

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3

Sundberg, Steven T. "A biblical development of the doctrine of eternal, conscious torment." Online full text .pdf document, available to Fuller patrons only, 1999. http://www.tren.com.

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4

Nilsson, Kristina L. "Planning in a sustainable direction - the art of CONSCIOUS CHOICES." Doctoral thesis, KTH, Infrastructure, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3652.

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<p>A main challenge facing spatial planning today issustainable development, in official documents defined asecological, social and economic sustainability. In a powerperspective these three dimensions can be characterised ascompeting discourses. Another challenge facing local authorityplanners is how to work in open processes with a growing numberof actors and stakeholders, in addition often as parties inchanging organisations. Altogether this provides a very complexcontext for local authority spatial planning and itsprofessional planners.</p><p>This report is based on an investigation of how

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5

Sukhdeo, Beverley Amanda Faith. "A conscious leadership model to achieve sustainable business practices." Thesis, Nelson Mandela Metropolitan University, 2015. http://hdl.handle.net/10948/5885.

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Business sustainability is a fundamental concern amongst business leaders and it is imperative that business defines an environmentally and socially sustainable path to financial prosperity. This focus on sustainable business practices has been caused by the perceived contribution of businesses to undesirable conditions such as environmental and social degradation including global warming and the global financial crises. This study suggests that a leadership style that differs from leadership that is currently causing business unsustainability is needed in order to achieve the goal of sustaina

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6

Castonguay, Andree. "Advancing the measure of self-conscious emotions: development & validation of the body and appearance-related self-conscious emotions (BASES) & the body-related self-conscious emotions fitness scales (BSE-FIT) scales." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119342.

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It is important to advance body image and self-conscious emotion research and theory by understanding the array of possible body-related self-conscious emotional experiences and their respective outcomes. Investigating these specific emotions requires the development and use of an instrument designed to capture both positive and negative appearance and fitness-related self-conscious emotional experiences. The purpose of the two interrelated measurement development studies was to develop and evaluate select psychometric properties of two self-report instruments of body-related self-conscious em

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7

Voss, Corrie A. "The narrative journey of the conscious leader." Bowling Green State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1490870727530644.

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8

Pike, Elizabeth. "Development of a questionnaire to measure self-conscious emotions in patients with COPD." Thesis, University of Leicester, 2018. http://hdl.handle.net/2381/43015.

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Chronic obstructive pulmonary disease (COPD) is a respiratory condition which can severely limit physical and social activities. Self-management and pulmonary rehabilitation programmes are commonly used to enhance clinical outcomes and quality of life in patients with COPD. However, completion rates for treatment programs are low and psychological factors remain poorly understood. The current literature review aimed to explore the impact of self-management programmes on psychological wellbeing in individuals with COPD. Four electronic databases were searched and fifteen studies met the inclusi

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9

Khandelwal, Radhika. "South Asian Americans’ Identity Journeys to Becoming Critically Conscious Educators." Digital Commons at Loyola Marymount University and Loyola Law School, 2020. https://digitalcommons.lmu.edu/etd/930.

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Typical identity stereotypes for South Asian Americans, such as the model minority myth, do not convincingly support a trajectory into K–12 education, as South Asian Americans are not readily seen as agents for social change. This qualitative study explored how South Asian American educators’ understanding of their ethnic and racial identity interplayed with their practice as critically conscious educators for social justice. Eleven participants who self-identified as social-justice-oriented were interviewed to share their experiences as South Asian American educators. Their responses revealed

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10

Mortlock, Simon Vernon. "Development of organostannanes for organic synthesis." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236133.

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11

McGeoch, Grant D. "Development and synthesis of novel organocatalysts." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/685/.

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The unfavourable use of metal-based catalysts in organic synthesis can be overcome by using small organic molecules; organocatalysts. Herein we report the development and synthesis of a novel range of organocatalysts derived from amino acids incorporating imidazole, thiourea and phosphoramide moieties to confer the capability to act as bifunctional organocatalysts. Our organocatalyst, a phosphoramide derived from valine, showed initial success in the catalytic allylation of aldimine with allyltrichlorosilane, producing 40% ee. Oxazoline catalysts derived from 2-pyridines have been shown to be

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12

Shaba, Reham. "Development of an improved psilocybin synthesis." Thesis, Uppsala universitet, Uppsala universitet Innovation (UU Innovation), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-420295.

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Psilocybin is a hallucinogenic compound found in fungi and is currently evaluated inclinical trials for treatment of depression, anxiety and addiction. Psilocybin is aprodrug of the pharmacologically active metabolite, psilocin. The synthetic route topsilocybin relies on synthesizing psilocin from the starting material, 4-hydroxyindoleand latter converting psilocin into psilocybin by phosphorylation. The synthesis ofpsilocybin has been challenging because of the labile nature of the phosphorylationdibenzyl ester reagent and related intermediates. Several attempts to optimizepsilocybin synthesi

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13

Meloni, Marco Massimiliano. "Synthesis and development of novel silicon linkers for solid phase synthesis." Thesis, University of Southampton, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408974.

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14

Schuster, Christopher Henry. "Synthesis and Utility of Organoboron Reagents for Enantioselective Synthesis." Thesis, Boston College, 2014. http://hdl.handle.net/2345/bc-ir:103558.

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Thesis advisor: James P. Morken<br>Described herein are three distinct projects centered on the formation and use of carbon-boron bonds. In the first, the enantioselective platinum-catalyzed 1,4-diboration of trans-1,3-dienes is advanced in both selectivity and scope through the development of a novel class of electron rich chiral monodentate phosphines. Under the action of the new ligands, highly selective diboration is maintained at reduced loadings of catalyst. Secondly, enantioenriched 1,2-bis(pinacol boronates) are engaged in regioselective Suzuki-Miyaura cross-coupling with aryl and viny

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15

Vass, Elaine Margaret. "Development of next generation methanol synthesis catalysts." Thesis, University of Glasgow, 2005. http://theses.gla.ac.uk/4113/.

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The main aim of this project was to re-visit the area of copper and cerium containing catalysts for use in the methanol industry. The goals were not only to prepare more robust copper/cerium catalysts, but also to further investigate the species that contributed to the high activity of the copper/cerium intermetallic catalysts. Initially a series of copper and cerium catalysts supported on silica or alumina were prepared. The preparation method was chosen so as to maximise the metal dispersion over the support. Methanol decomposition was used to investigate the activity of the prepared catalys

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16

Patterson, Isaac. "Trustworthy system development through high-level synthesis." Thesis, Monterey, California: Naval Postgraduate School, 2014. http://hdl.handle.net/10945/43974.

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Approved for public release; distribution is unlimited<br>Major processor manufacturers have embraced the high-level synthesis (HLS) design philosophy. HLS offers the potential to explore the design space of electronic circuits and systems more efficiently than traditional methods. In this thesis, we investigate the ap-plication of HLS to hardware-oriented security and trust by developing a model of a simple 16-bit Central Processing Unit in the SystemC modeling language. We enhanced our processor with a simple security mechanism that enforces a memory integrity policy. The integrity policy al

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17

Jenkins, Kerry. "Development of dynamic resolutions for asymmetric synthesis." Thesis, University of Sussex, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241636.

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18

Watson, Christopher. "Development of new methods for peptide synthesis." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/14647.

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The preparation and evaluation of a number of carboxylic acid protecting groups is reported. The preparation of aspartic acid side chain esters of 9-anthracenylmethanol, 1-(9'-anthracenyl0-3-methylbutan-3-o1, 1-4(4'-fluorophenyl)-2-methylpropan-2-o1, dibenzosuberol and 4-methyl-2,6,7-trioxobicyclo[2.2.2]octane are described. The conversion of these into suitably protected N<SUP>α</SUP>- Fmoc derivatives for the solid phase synthesis of peptides has been carried out and the comparison with established protection strategies is discussed. Model compounds of these derivatives have been prepared wh

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19

Wang, Guocheng. "Design, synthesis and development of PDE5 inhibitors." Thesis, Aston University, 2009. http://publications.aston.ac.uk/15405/.

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This research project is concerned with the design, synthesis and development of new phosphodiesterase 5 (PDE5) inhibitors with improved selectivities and lower toxicities. Two series of a 5 member and a 6 member ring fused heterocyclic compounds were designed, and synthesized. By alteration of starting materials and fragments, two virtual libraries, each is consisted of close to hundred compounds, were obtained successfully. The screening of sexual stimulation activity with rabbits demonstrated both groups of compounds were able to stimulate rabbit penile erection significantly. The following

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20

Ao, Min. "Catalyst Development for Higher Alcohol Synthesis (HAS)." Thesis, Curtin University, 2017. http://hdl.handle.net/20.500.11937/54164.

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This study investigated the effects of partial substitution at the A- and/or B-site of LaCoO3 perovskite catalysts (ABO3) on higher alcohol synthesis (HAS) from syngas. The catalyst properties and catalytic performances were well studied for the La1-xSrxCo1-y-zNiyCuzO3 catalysts. A-site substitution affected CO conversion, while B-site substitution affected higher alcohol selectivity. The effects of alkali promoters and reaction conditions were also discussed. This study proved that partially-substituted perovskites are promising candidates for the enhancement of HAS.

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21

Cantekin, Seda. "The Development Of The Novel Synthesis For Conduritols." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/3/12607609/index.pdf.

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Conduritols have attracted a great deal of attention in recent years owing to biological activities exhibited by them and also their usefulness in the synthesis of other natural products and pharmaceuticals. Conduritols show interesting inhibitor activity for some glycosidases and serve as important intermediates in the synthesis of inositols. In this study, novel synthetic strategies leading to highly functionalized cyclohexene derivative containing an aromatic ring, namely phenyl-substituted conduritol was achieved successfully for the first time. As the starting material, substituted benzoq

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22

Mcausland, Donald Euan Reynolds. "Arynes in synthesis : new reaction and precursor development." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/arynes-in-synthesisnew-reaction-and-precursor-development(1f59c4ec-dc6d-487b-9bc4-c5a99d5bc030).html.

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The arylation of readily accessible N-tosyl hydrazones has been achieved using arynes generated in situ under mild conditions. The resulting N-tosyl-N-aryl hydrazones undergo a one-pot Fischer indole reaction on the addition of acid, giving a synthesis of protected indoles that avoids handling unstable intermediates and arylhydrazines. A new route to functionalised 2-(trimethylsilyl)phenyl triflate aryne precursors via Suzuki cross-coupling has been developed. The method allows the incorporation of a wide range of aryl and heteroaryl groups and reactions of arynes generated from these novel pr

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23

Bathgate, B. "Plastid protein synthesis during fruit development and ripening." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.482881.

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24

Yin, H. B. "Development of charged membranes : synthesis, characterisation and application." Thesis, Swansea University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636712.

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The main objective of this work was to investigate the preparation, characterisation and application of a group of charged ultrafiltration/nanofiltration (UF/NF) membranes. The study was mainly undertaken on the polysulfone (PSU)/sulfonated poly(ether ether ketone) (SPEEK)/N-methyl-2-pyrrolidinone system. The addition of a small amount of SPEEK, in the range of 0.5-5 wt.%, in the polymer blend gave rise to a class of UF/NF charged SPEEK/PSU membranes. All charged membranes had substantially higher water flux, salt rejection, porosity and greatly reduced particle adhesion compared to the PSU ba

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25

Wright, Emma. "The development of organolead reagents in organic synthesis." Thesis, University of Oxford, 1995. http://ora.ox.ac.uk/objects/uuid:3cf2abd7-79f8-4963-82ad-ea3bb6eb98db.

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This thesis describes the synthesis of novel lead(IV) tetracarboxylates and the development of their use in carbon-carbon bond formation processes, with a particular emphasis on the construction of chiral, quaternary centres. Organolead(IV) tricarboxylates have been widely used in the functionalisation of a range of β-dicarbonyl compounds, and the available evidence suggests that these reactions occur by a ligand coupling mechanism. For this reason, by using chiral lead(IV) compounds, it may be possible to achieve a transfer of asymmetry in the bond formation reaction. A variety of achiral and

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26

Schroeder, Deborah. "Development of computer programs to aid synthesis planning." Thesis, University of Leeds, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329976.

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27

Lee, Wen-Hsuan Ph D. Massachusetts Institute of Technology. "Development of microreactor setups for microwave organic synthesis." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/98157.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2015.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 135-140).<br>The main contribution of this work is the understanding of microwave heating and the microreactor design challenges involved through both chemical experiments and computational models. The original goal of this research is to develop a microreactor system in order to carry the microwave organic synthesis in continuous flow format and to understand the basic phenomena of microwave heating through accu

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28

Martinelli, Joseph R. "The development of palladium-catalysts for organic synthesis." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39738.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2007.<br>Vita.<br>Includes bibliographical references.<br>Chapter 1. Suzuki-Miyaura coupling reactions of aryl and heteroaryl halides with aryl-, heteroaryl and vinyl boronic acids proceed in very good to excellent yield with the use of 2-(2',6'-dimethoxybiphenyl)-dicyclohexylphosphine, SPhos. Additionally, a comparison of the reactions with SPhos and with 2- (2',4',6'-triisoprc'pylbiphenyl)-diphenylphosphine is presented that is informative in determining the relative importance of ligand bulk and electron-donating ab

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29

Hays, David S. (David Scott) 1970. "The development of organotin reagents for organic synthesis." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/47483.

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30

Valsborg, Jacob Stenmann. "Design and synthesis of radioligands in drug development /." [Cph.] : Royal danish School of Pharmacy, Department of Medicinal Chemistry, 2002. http://www.dfh.dk/phd/defences/jacobvalsborg.htm.

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31

Fung, Ho Ki. "Synthesis and development of manufacturing processes for biopharmaceuticals /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?BIEN%202003%20FUNG.

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32

Savage, Michelle L. "Synthesis and development of light-activated molecular probes." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:3532bd21-ad68-4e8e-9e77-9fd6b620d4f3.

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Judicious addition of photolabile caging groups (PCGs) to protect biologically im- portant molecules, has enabled the development of many powerful chemical tools for the study of biological processes. These tools have the potential to be activated in a cellular setting by irradiation with light of appropriate wavelengths, restoring functionality, with excellent spatial and temporal control. This D. Phil. dissertation highlights two biologically relevant examples where PCGs can be applied: (i) 4,5-dimethoxynitrobenzyl (DMNB) caged derivatives of GSH and ESG, were synthesised and uncaging of the

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33

K, Zubaidha P. "Synthesis of heritol and development of new methodologies." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1992. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3050.

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34

Smelt, Kathryn Helena. "Synthesis of L-fucose analogues." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362080.

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35

Basmadjian, Christine. "Development of new approaches for the synthesis of flavaglines." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAF019/document.

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Nous avons développé deux méthodes originales de synthèse de cyclopenténones fonctionnalisées et découvert de nouveaux réarrangements d’alcools 1-styryl propargyliques catalysés par des acides.Ce travail de thèse a aussi permis de mettre en évidence les limitations d’une méthode de synthèse des flavaglines développée par des chercheurs de la compagnie Bayer. De plus, la resynthèse de certaines flavaglines et la synthèse d’une sonde de fluorescence originale ont permis de mieux caractériser le mode d’action et le potentiel thérapeutique des flavaglines pour leurs effets anticancéreux (notamment

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36

Paul, Diana Rachel. "The development of new organolead reagents in organic synthesis." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320635.

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37

Lewin, Paul Dominic. "Embryology and the evolutionary synthesis : Waddington, development and genetics." Thesis, University of Leeds, 1998. http://etheses.whiterose.ac.uk/1455/.

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The role of embryology, genetics and morphology within mid twentieth century evolution theory, is discussed in the context of the growth to dominance of natural selection as the orthodox mechanism of adaptive evolution. The unification of neo-Mendelian heredity and neo-Darwinian selection theory, is descnbed as the core of modern synthetic neo-Darwinism as it emerged in 1930s mathematical population genetics. As selectionism strengthened within synthetic neo-Darwinism, embryological development was excluded from its traditional causal role in adaptive evolution within the "old synthesis" of Ha

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38

Ng, Andrew Eng Jwee. "Switched-current filtering systems : design, synthesis and software development." Thesis, University of Glasgow, 1999. http://theses.gla.ac.uk/5040/.

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Allpass filters are commonly employed in many applications to perform group delay equalisation in the passband. They are non-minimum phase by definition and are characterised by poles and zeros in mirror-image symmetry. SI allpass filters of both cascade biquad and bilinear-LDI ladder types have been in existence. These were implemented using Euler based integrators. Cascade biquads are known to have highly sensitive amplitude responses and Euler integrators suffer from excess phase. The equalisers that are proposed here are based on bilinear integrators instead of Euler ones. Derivation of th

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39

Kitching, Martin S. "Development of methodology for the synthesis of isoindolinone libraries." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247902.

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40

Lizos, Dimitrios. "Development of free radical methodology for natural products synthesis." Thesis, University of Strathclyde, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273786.

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41

Szeto, Peter. "Recent development in indolizidine alkaloids : a synthesis of (-)-slaframine." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294850.

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42

Marrison, Shaun. "Development of new radical cyclisation methodologies for carbocycle synthesis." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247637.

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43

Chen, Wenqian. "Membrane enhanced peptide synthesis (MEPS) : process development and application." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/51499.

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Peptides are polymers of amino acids and are better drug candidates than traditional small-molecule compounds due to high specificity and potency. Conventional synthesis methods include Solid Phase Peptide Synthesis (SPPS) and Liquid Phase Peptide Synthesis (LPPS), which have different technical limitations. Significant improvements can be made by a new technology, Membrane Enhanced Peptide Synthesis (MEPS), which integrates nanofiltration into LPPS for the purification of intermediate products. The research work described in this thesis is an outcome of the MemTide consortium (Imperial Colleg

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44

Bourne, Samuel. "Development of novel gas-flow methodologies for pharmaceutical synthesis." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708895.

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45

Frias, Carolina Padovan. "Design and development of halodeboronation methods for organic synthesis." Thesis, University of Strathclyde, 2018. http://digitool.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=30296.

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Boronic acids and derivatives are one of the most useful classes of compounds in organic synthesis. Methodologies involving diboron systems have emerged recently as a rapid and powerful approach to synthesize complex molecules. Selectivity in these systems is a key aspect and is typically achieved through protecting group strategies. In this approach one boron species is rendered inert under reaction conditions, while the unprotected boron residue can be selectively manipulated. Nonetheless those methods have the drawback of requiring additional actions to allow subsequent functionalisation (s

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46

Rainka, Matthew P. (Matthew Paul). "Development of transitional metal-catalyzed reactions for organic synthesis." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/32494.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005.<br>Vita.<br>Includes bibliographical references.<br>Chapter 1. A general catalyst system for the synthesis of tetra-ortho-substituted biaryls via the Suzuki-Miyaura cross-coupling reaction is described. It was found that the most efficient catalyst system is based on a phenanthrene-substituted biaryl phosphine ligand. Utilizing this ligand, a number of tetra-ortho-substituted biaryls were synthesized in good to excellent yields. Chapter 2. A procedure for the arylation of methyl and cyclic ketone enolates with o-

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47

Lim, Chee-Kiang. "The development of new organotin reagents for organic synthesis." Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/32169.

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48

Curtis, A. D. M. "The development of sugar-based quinones for asymmetric synthesis." Thesis, University of Manchester, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679590.

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49

Miao, Lei. "Synthesis of Amphibian Alkaloids and Development of Acetaminophen Analogues." ScholarWorks@UNO, 2009. http://scholarworks.uno.edu/td/985.

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The focus of these studies has been toward the development of new synthetic methods and procedures for the synthesis of novel compounds with unique biological properties. This research has led to the development of two new synthetic strategies for the construction of two novel amphibian alkaloids. In addition, the efforts have led to the large-scale process for the preparation of a novel analgesic compound. The regioselective ring opening of lactones (δ-valerolactone and γ-butyrolactone) with aryllithium reagents is reported for the construction of a series of δ-hydroxyarylketones and γ-hydrox

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50

Slaughter, Kimari. "Synthesis and Development of Potential CB1 Receptor Neutral Antagonists." ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1483.

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Cannabis and its derivatives have been used for both medicinal and recreational purposes. The study of this plant led to the discovery of over 60 cannabinoids, found exclusively in cannabis, that contribute to the behavioral effects of cannabis use, the most common is delta-9-tetrahydrocannabinol. Cannabinoid receptors function to increase activity in the mesolimbic dopamine reward system. Dopamine is a neurotransmitter that plays a major role in addition and its regulation plays a crucial role in mental and physical well-being. There is evidence that CB1 receptors are important to the reinfor

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