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1

Pop, Lucian, Nicolae Bacalbasa, Irina Balescu, Ioan D. Suciu, Roxana Elena Bohiltea, and Claudia Stoica. "Hysteroscopic sterilisation." Romanian Journal of Medical Practice 16, S7 (2021): 46–47. http://dx.doi.org/10.37897/rjmp.2021.s7.14.

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A patient requesting sterilization envisages an easy to perform, safe cheap and reversible method. Despite best efforts of researchers and pharma companies, such a device has not been produced yet. Female sterilization is one of the most common procedures and encompasses tubal ligation, laparoscopic salpingectomy or hysteroscopic sterilization. This short review focuses on role of hysteroscopy on sterilization and informed consent as sterilization is a legacy for the rest of a woman life.
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2

Daniel, François-Joseph. "Sensory Science in Tension." Science & Technology Studies 33, no. 2 (2020): 49–65. http://dx.doi.org/10.23987/sts.60784.

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For the last 15 years, sensory science has frequently been recommended to industrial actors to monitor odours, assess the quality of the environment and improve their factories’ functioning. Resident “sniffing teams” have been put in place in different contexts to assess odorous pollution. These teams are groups of local residents living in the neighbourhoods of industrial facilities, who have been trained to report pollution emissions. This article describes these teams as sensory devices and argues that their functioning relies on the consent of the residents to allow themselves to “be affec
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Behmer Hansen, Rosemary Talbot, and Kavita Shah Arora. "Consenting to invasive contraceptives: an ethical analysis of adolescent decision-making authority for long-acting reversible contraception." Journal of Medical Ethics 44, no. 9 (2018): 585–88. http://dx.doi.org/10.1136/medethics-2018-104855.

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Since USA constitutional precedent established in 1976, adolescents have increasingly been afforded the right to access contraception without first obtaining parental consent or authorisation. There is general agreement this ethically permissible. However, long-acting reversible contraception (LARC) methods have only recently been prescribed to the adolescent population. They are currently the most effective forms of contraception available and have high compliance and satisfaction rates. Yet unlike other contraceptives, LARCs are associated with special procedural risks because they must be i
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4

Zhang, Ling, Wentao Shi, Shenji Lu, et al. "Prognostic factor analysis in patients with temporomandibular disorders after reversible treatment: study protocol for a prospective cohort study in China." BMJ Open 11, no. 7 (2021): e048011. http://dx.doi.org/10.1136/bmjopen-2020-048011.

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IntroductionTemporomandibular disorders (TMDs) are complex multifactorial disorders. Reversible treatment has been suggested for the initial management of TMD; however, comparable therapeutic effects of different reversible intervention modalities remain controversial. Various biopsychosocial factors, which may be putative prognostic factors that influence the response to reversible treatment for TMD, have been reported to increase the risk of developing first-onset TMD. However, there is a paucity of research that aims to identify prognostic factors associated with the clinical outcomes of re
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Ali, Fauzia, Tazeen Fatima Munim, Shabnum Nadeem, Aisha Khatoon, and Zubaida Masood. "Experience of Women after Immediate Postpartum Insertion of Intrauterine Contraceptive Device (PPIUCD), a Long-Acting Reversible Contraception." ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE 27, no. 1 (2022): 16–22. http://dx.doi.org/10.58397/ashkmdc.v27i1.310.

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ABSTRACT
 Objective: To assess the experience (during and post procedure) of women after immediate postpartum and post placental Insertion of intrauterine contraceptive device (IUCD), a long acting reversible contraceptive (LARC).
 Methods: This prospective and longitudinal study was conducted during February 2019 to September 2019 in Gynae and Obstetrics department Unit 1 at Abbasi Shaheed Hospital. All 141 booked and non-booked patients who delivered in the hospital and received immediate postpartum intrauterine contraceptive device (PPIUCD),either post placental, intra cesarean or
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Yang, Shilong, Lu Leng, Ching-Chun Chang, and Chin-Chen Chang. "Reversible Adversarial Examples with Minimalist Evolution for Recognition Control in Computer Vision." Applied Sciences 15, no. 3 (2025): 1142. https://doi.org/10.3390/app15031142.

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As artificial intelligence increasingly automates the recognition and analysis of visual content, it poses significant risks to privacy, security, and autonomy. Computer vision systems can surveil and exploit data without consent. With these concerns in mind, we introduce a novel method to control whether images can be recognized by computer vision systems using reversible adversarial examples. These examples are generated to evade unauthorized recognition, allowing only systems with permission to restore the original image by removing the adversarial perturbation with zero-bit error. A key ch
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7

Rafique, Irum, Alruba Taimoor, Aamir Nazir, Humaira Bashir, Rakhshanda Inam Khan, and Safia Khan. "SAFETY AND EFFICACY OF A SINGLE-ROD SUBDERMAL CONTRACEPTIVE ETONOGESTREL IMPLANT(IMPLANON): SIX MONTH FOLLOWUP EXPERIENCE IN WOMEN OF REPRODUCTIVE AGE." Pakistan Journal of Physiology 18, no. 3 (2022): 23–26. http://dx.doi.org/10.69656/pjp.v18i3.1468.

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Background: Etonogestrel implant is an effective and healthier contraceptive method for women in developing countries because of its convenience, price, long duration, and safety of use while breastfeeding. It has high possibility of return to fertility after removal. The objective of the study was to determine the efficacy in term of frequency of compliance of etonogestrel implant and side-effects in women receiving it as reversible contraception. Methods: A descriptive case series was designed and was conducted in Family Planning Centre, Federal Government Polyclinic, Islamabad. The study wa
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Sadaf, Rabeea, Laila Nazir, Samreen, Saman Muddassir, Engineer Abdul Bashir, and Kiran Jehangir. "compare the clinical efficacy and side effects of implant (JADELLE) and IUCD (COPPER T)." International journal of health sciences 7, S1 (2023): 1683–96. http://dx.doi.org/10.53730/ijhs.v7ns1.14400.

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This study aims to compare the performance and side effects of the subdermal implant JADELLE and intrauterine contraceptive device Copper-T as long-acting reversible contraceptive methods. The study design involved a comparative analysis of Jadelle and Copper-T contraceptives, assessing clinical performance and side effects. Sample data from 336 participants was collected using stratified random sampling, with standardized instruments for demographic information, clinical assessment, and contraceptive side effects. Inclusion criteria were reproductive-age multipara women, while exclusion crite
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Sadaf, Rabeea, Laila Nazir, Samreen Samreen, Saman Muddassir, Engineer Abdul Bashir, and Kiran Jehangir. "To compare the clinical efficacy and side effects of implant (Jadelle) and IUCD (Copper T)." International journal of health sciences 7, S1 (2023): 1723–36. http://dx.doi.org/10.53730/ijhs.v7ns1.14406.

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This study aims to compare the performance and side effects of the subdermal implant JADELLE and intrauterine contraceptive device Copper-T as long-acting reversible contraceptive methods. The study design involved a comparative analysis of Jadelle and Copper-T contraceptives, assessing clinical performance and side effects. Sample data from 336 participants was collected using stratified random sampling, with standardized instruments for demographic information, clinical assessment, and contraceptive side effects. Inclusion criteria were reproductive-age multipara women, while exclusion crite
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10

Seres, László, Gyöngyi Pethő, Zoltán Pető, and Tünde Pető. "Átmeneti kettős látás és szemizombénulás fogászati érzéstelenítést követően." Orvosi Hetilap 159, no. 52 (2018): 2212–16. http://dx.doi.org/10.1556/650.2018.31233.

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Abstract: Dental anaesthesia is one of the most frequently performed medical procedures. Although the frequency of ocular complications is low, these can be alarming and can potentially give rise to medicolegal issues. Dentists and oral surgeons should be well-informed of these adverse reactions. Ophthalmologists and emergency physicians might be required for appropriate care of these patients. Fortunately, most ocular complications related to dental anesthesia are transient. Differential diagnosis includes stroke and intracranial hemorrhage and so vital signs are to be closely monitored. The
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Gupta, Nidhi, and Akanksha . "A prospective observational study conducted in tertiary teaching hospital of Uttar Pradesh to compare safety and efficacy of PPIUCD and interval IUCD (380A)." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 1 (2018): 295. http://dx.doi.org/10.18203/2320-1770.ijrcog20185442.

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Background: The objective of this study was to compare the efficacy and safety of PPIUCD and interval IUCD.Methods: This was a prospective observational study conducted on women attending the OPD and indoor services of S.N. Medical college, Agra. 800 women willing for PPIUCD insertion were included in the study after informed consent excluding chorioamnionitis, PROM>18 hours, unresolved PPH and puerperal sepsis. Another 200 willing women were inserted interval IUCD according to MEC criteria of WHO. All were followed up for 1 year.Results: It was found that rate of expulsion was more in PPIU
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Chandra Bhowmik, Goutom, Sanjib Chowdhury, Kamrul Hasan, et al. "Survival of Cardiac Arrest with Withdrawal of Mechanical Ventilator: A Case Report." Asploro Cardiovascular Case Reports and Research 2, no. 1 (2025): 6–10. https://doi.org/10.36502/2025/accrr.6104.

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Background: In-hospital cardiac arrest (IHCA) is a common clinical event with extremely poor outcomes associated with cardiovascular disease. Although IHCA, associated with a high mortality rate, has received little attention compared to other cardiovascular conditions such as myocardial infarction and stroke [1]. The survival rate of IHCA to discharge is approximately 25% [2]. We report a case of cardiac arrest survival in a patient with a history of old MI (anterior), SVD, and uncontrolled DM and HTN. The patient was initially treated with resuscitation according to guidelines due to the una
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13

Qureshi, Bushra Qaiser, Emad Uddin Siddiqu, and Sayyeda Ghazala Kazi. "he outcome of Ketamine and Propofol for Procedural Sedation and Analgesia (PSA) in Pediatric Patients in the Emergency Department: A Cross-Sectional Study." Journal of Bahria University Medical and Dental College 14, no. 01 (2024): 24–29. http://dx.doi.org/10.51985/jbumdc2023275.

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bjectives: We aim to evaluate the outcomes of Ketamine and Propofol for PSA in pediatric Pakistani Emergency Department (ED) patients. Our primary objective is to observe sedation duration and recovery time. Secondary objective is to assess the need for repeat doses and potential complications associated with the use of these drugs. Study Design & Setting: Descriptive cross-sectional study. Urban tertiary care hospital: Aga Khan University Hospital (AKUH) ED, Pakistan. Methodology: 179 eligible patients requiring painful procedures in the emergency, under 16 years, selected through nonprob
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Suthar, Kiran, Pramod Sharma, Manish Verma, and Vishnu Kr Goyal. "Efficacy and safety of high dose hydroxyurea in transfusion dependent thalassemic children: a quasi experimental study." International Journal of Contemporary Pediatrics 4, no. 4 (2017): 1514. http://dx.doi.org/10.18203/2349-3291.ijcp20172697.

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Background: This study was conducted to find out whether high dose hydroxyurea is an effective and safe modality, in inducing haemoglobin synthesis to decrease blood transfusion requirement in transfusion dependent thalassemics.Methods: This quasi experimental un-control before and after comparison study was conducted in Thalassemia Day Care Centre, Department of Pediatrics over a period of six months after obtaining an approval from the Institute’s ethical committee. Fifty transfusions dependent thalassemic children belonging from 2 to 18 yrs were given hydroxyurea in dose of 20mg/kg after ge
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15

Hostiuc, S., I. Negoi, and E. Drima. "Decisional capacity in patients with acute delirium. A Rawlsian approach." European Psychiatry 41, S1 (2017): S581. http://dx.doi.org/10.1016/j.eurpsy.2017.01.872.

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Delirium is characterized by a temporary, usually reversible, cause of mental alteration; it can occur at any age, but affect most often the elderly. Delirium patients may also present acute psychotic episodes, which might make them decisionally incompetent. In order to assess decisional capacity, Fan et al developed a two-stage approach, which tries to analyse:– the presence of delirium, using the Confusion Assessment Method;– a proper analysis of the decisional capacity.Often, in patients with decreased decisional capacity, physicians must assess which ethical principle should respect first
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16

Yadav, Sumitra, Ruchi Joshi, and Monica Solanki. "Knowledge attitude practice and acceptance of postpartum intrauterine devices among postpartal women in a tertiary care center." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 4 (2017): 1507. http://dx.doi.org/10.18203/2320-1770.ijrcog20171418.

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Background: PPIUCDs are the only method for couples requesting a highly effective and reversible, yet long acting, family planning method that can be initiated during the immediate postpartum phase. World Health Organization (WHO) medical eligibility criteria state that it is generally safe for postpartum lactating women to use a PPIUCD, with the advantages outweighing the disadvantages. PPIUCDs are cost-effective and they are low-cost intervention that reduces maternal, infant, and under-five Child mortality.Methods: After approval from the ethical committee and consent from the patients, the
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17

Noel, Patrick, Laurent Layani, Thierry Manos, et al. "The Reflux and BariClip: Initial Results and Mechanism of Action." Journal of Clinical Medicine 11, no. 22 (2022): 6698. http://dx.doi.org/10.3390/jcm11226698.

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Introduction: Laparoscopic BariClip Gastroplasty (LBCG) represents a new bariatric procedure that mimics the principle of the Laparoscopic Sleeve Gastrectomy (LSG), but using a completely reversible mechanism, which is essential for gastroesophageal reflux disease (GERD). The purpose of our study was to evaluate the evolution of GERD following the initial experience with LBCG. Methods: The first 43 obese patients who underwent LBCG performed by the same surgeon in two different medical centers in May 2018–December 2019 were included in the current study. Twelve patients had issues of reflux, r
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Nusrullah, Muhammad, Muhammad Younus, and Yasir Nasir. "Relationship between Arterial and Venous Blood Gases in Patients Presenting with Chronic Obstructive Pulmonary Disease." Annals of King Edward Medical University 24, no. 1 (2018): 684–88. http://dx.doi.org/10.21649/akemu.v24i1.2343.

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Arterial blood gas analysis is an important test for determining acid base balance of the body. Chronic obstructive pulmonary disease is characterized by chronic airflow limitation which is not fully reversible and it can lead to respiratory failure. Objective: To determine the correlation between arterial and venous blood gases in patients presenting with chronic obstructive pulmonary disease. Material and Methods: This cross sectional study was conducted at Department of Chest Medicine, Mayo Hospital, Lahore, Pakistan. After meeting the inclusion criteria, 100 patients were enrolled. Informe
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19

Dalle Ave, Anne L., and James L. Bernat. "Uncontrolled Donation After Circulatory Determination of Death: A Systematic Ethical Analysis." Journal of Intensive Care Medicine 33, no. 11 (2016): 624–34. http://dx.doi.org/10.1177/0885066616682200.

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Uncontrolled donation after circulatory determination of death (uDCDD) refers to organ donation after a refractory cardiac arrest. We analyzed ethical issues raised by the uDCDD protocols of France, Madrid, and New York City. We recommend: (1) Termination of resuscitation (TOR) guidelines need refinement, particularly the minimal duration of resuscitation efforts before considering TOR; (2) Before enrolling in an uDCDD protocol, physicians must ascertain that additional resuscitation efforts would be ineffective; (3) Inclusion in an uDCDD protocol should not be made in the outpatient setting t
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20

Fomenko, N. M., M. I. Oleksyn, O. B. Synoverska, T. H. Berezna, and Y. L. Kryshtafovych. "A case of mitochondrial episodic myopathy (variant without optic atrophy and reversible leukoencephalopathy) in the Carpathian region." Modern pediatrics. Ukraine, no. 3(131) (April 28, 2023): 134–38. http://dx.doi.org/10.15574/sp.2023.131.134.

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Mitochondrial episodic myopathy with/or without optic nerve atrophy and reversible leukoencephalopathy (MEOAL, OMIM 251900) belongs to rare primary mitochondrial myopathies, caused by nuclear genome DNA mutations with autosomal recessive inheritance. Purpose - to inform about the case of this current rare mitochondrial miopathy and encrease the knowledge of practical doctors in scope of diagnostics and treatment of the current orphan pathology Clinical case. In the clinical case being presented herein, the sick child had a severe course of the disease in the form of episodes of severe myopathy
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Μουμτζή (Sofia Moumtzi), Σοφία. "Contraception and sterilisation of patients with severe psychiatric disorders." Bioethica 2, no. 2 (2016): 51. http://dx.doi.org/10.12681/bioeth.19781.

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The number of individuals that suffer from psychiatric diseases rises exponentially as a result of the humanitarian crisis and social exclusion. The increase in the incidence of psychiatric disorders has serious consequences in the ability/right to reproduce and to proper child rearing in order to assure the children' normal social and professional inclusion. So the big ethical dilemma is if we should or if we should not apply contraception or sterilisation upon individuals that carry severe psychiatric disorders. Contraception is a mild method of birth control in comparison to sterilisation w
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Singata-Madliki, Mandisa, G. Justus Hofmeyr, Florence Carayon-Lefebvre d’Hellencourt, and Theresa Anne Lawrie. "Psychological, behavioural and physiological effects of three long-acting reversible contraception (LARC) methods: protocol for an ancillary study of the ECHO randomised trial." BMJ Open 7, no. 11 (2017): e019205. http://dx.doi.org/10.1136/bmjopen-2017-019205.

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IntroductionThis is the protocol for an ancillary study to the multicentre Evidence for Contraceptive Options and HIV Outcomes (ECHO) Trial, a three-arm randomised trial comparing the effects of depot medroxyprogesterone acetate (DMPA), the levonorgestrel (LNG) implant and the copper intrauterine device (IUD) on HIV incidence (NCT02550067pre-results). The ancillary study will compare other non-contraceptive effects of these three long-acting, reversible contraceptions about which there is little existing comparative evidence.Methods and analysisWomen randomised to IUD, DMPA and LNG implant (1:
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He, Xia, Jianhua Xu, and Jie Wen. "Therapeutic p53 gene agent in the treatment of refractory cancer cases: A phase I study." Journal of Clinical Oncology 31, no. 15_suppl (2013): 2543. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.2543.

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2543 Background: To evaluate the benefit of adding therapeutic p53 gene agent into the standard treatment regimens for refractory cancer cases. Methods: Recombinant adenoviral human p53 gene (rAd-p53), was given intravenously at a dose of 2×1012 viral particles /day on 5 consecutive days one week before routine anti-cancer treatment start, and was repeated after an interval of 16 days. The inclusion criteria include: 1.Pathologically confirmed recurrent cancers; 2. Disseminated cases; 3. Patients with key organ metastasis; 4.Unresectable lesions; 5.Chemo- or radio-therapy resistant cases. The
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Misra, Amar Kumar, Joydeep Mukherjee, Sanjay Kumar, et al. "A Study on Clinical Profile of Hemifacial Spasm in India and the Therapeutic Response to Botulinum Toxin Type A Injection as well as Pre and Postinjection Quality of Life." Journal of the Association of Physicians of India 70, no. 12 (2022): 44–47. http://dx.doi.org/10.5005/japi-11001-0161.

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Background: Hemifacial spasm (HFS) is a distressing, involuntary, irregular tonic-clonic contraction of the facial muscles innervated by the seventh cranial nerve. It affects the quality of life. Botulinum toxin is a preferred symptomatic treatment option for the condition. However, there is a lack of study in the Indian scenario. Therefore, we observed the demographic profile, clinical spectrum, therapeutic response, and adverse effects of botulinum toxin and assessed the quality of life in the pre and postinjection phases in our subjects with HFS. Materials and methods: The study design is a
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Wade, Dinesh, and Shweta Avinash Khade. "Evaluation of effect of pospartum intrauterine contraceptive device." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 5 (2019): 1852. http://dx.doi.org/10.18203/2320-1770.ijrcog20191931.

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Background: This study was done to compare and evaluate safety, efficacy and complications of PPIUCD and interval IUCD insertion and to generate evidence on the safety and effectiveness of these two types of IUCD insertions.Methods: This prospective study was carried out at tertiary care center and Teaching Institute in the Department of obstetrics and gynecology. All enrolled patients in obstetrics and gynecology from 1/2/16 to 31/7/16 were included in this study. Women fulfilling inclusion criteria were included in the study after informed consent. Study protocol was approved by ethics commi
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Tahir, Nangiyal Ahmad, and Saima Ghufran. "Causes Of Unilateral Blindness." Journal of Clinical and Community Ophthalmology 1, no. 01 (2023): 35–38. https://doi.org/10.71177/jcco.v1i01.27.

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Aim: To enlist the frequency of diseases that causes unilateral blindness (reversible & irreversible both). Study Design: Cross Sectional study Duration and setting of study: This study was done at OPD Ophthalmology, Hayatabad Medical Complex (HMC) Peshawar, from 1st March, to 30th June, 2019. Methods: In this study all patients presenting with unilateral blindness to eye outpatient department, Hayatabad Medical Complex were included. Blindness was defined as presenting visual acuity of less than 3/60 in any one eye. After taking consent, the data was collected through Pre-designed questio
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Shepperson, Andrea. "The Digital Aesthetic Test Drive." Primary Dental Journal 12, no. 2 (2023): 46–56. http://dx.doi.org/10.1177/20501684231174494.

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The burgeoning public interest in techniques to enhance a smile has led to demand on clinicians that require important steps in the pre-treatment approval process. Digital dentistry provides a new level of planning and visualisation, improving clinical risk assessment and patient engagement. Dentists must acquire a sound understanding of aesthetic design parameters, including physiologic limitations, and must match patient expectations with clinical reality. Digital design offers flexibility not obtainable with the conventional analogue wax up. Multiple versions of a design can be viewed in a
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Kumar, Prem, Mayur Khandelwa, H. S. Kumar, Neeti Sharma, and Shankar Lal Jakhar. "A Prospective Comparative Study of Sensorineural Hearing Loss in Patients of Head and Neck Cancers Treated with 2-D RT vs 3-D CRT." Asian Pacific Journal of Cancer Care 9, no. 1 (2024): 87–92. http://dx.doi.org/10.31557/apjcc.2024.9.1.87-92.

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Background: SNHL is disabling for the patient, since it has a chronic and often Progressive natural history. sensorineural hearing loss is irreversible, whereas conductive hearing loss (as often found after radiotherapy) is mainly reversible. Material and Methods: This prospective randomized study was conducted in Department of Radiation Oncology, S P medical college Bikaner, Rajasthan. The study was done from November 2020 to October 2021. After taking informed consent total of 50 patients of biopsy proven squamous cell carcinoma of head and neck region randomly distributed among Group A who
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Priyanka, Kanni, Bangonda Prema, Shashidhar Yuvaraj, and Margutti Akshay. "A Comparative Study of Desflurane and Sevoflurane for Hemodynamic Ability and Postoperative Outcome under General Anesthesia." International Journal of Pharmaceutical and Clinical Research 15, no. 10 (2023): 380–84. https://doi.org/10.5281/zenodo.11248224.

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General anaesthesia can be defined as reversible depression of central nervous system resulting in loss of consciousness and absence of response to external stimuli. General anaesthesia is usually defined as triad of amnesia, analgesia and muscle relaxation. Inhalational anaesthetics are the drugs which are most commonly used for the maintenance of general anaesthesia. Adding only a small amount of volatile anaesthetic to the inspired mixture of gases results in a state of unconsciousness and amnesia.&nbsp;<strong>Materials and Methods:</strong>&nbsp;This study done at Dept of Anaesthesiology,
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Nahar, Khadiza Nurun, Parveen Fatima, Farhana Dewan, et al. "Acceptability and Feasibility of Postpartum Intra Uterine Contraceptive Device Insertion in Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh." Bangladesh Medical Journal 47, no. 3 (2019): 25–31. http://dx.doi.org/10.3329/bmj.v47i3.43495.

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Worldwide intra uterine contraceptive device (IUCD) is a reversible method of contraception. Postpartum IUCD insertion is labeled when IUCD is inserted within 10 minutes to 48 hours of expulsion of placenta. The objective of the study was to analyze the acceptability and feasibility of immediate postpartum intrauterine contraceptive device (PPIUCD) in a tertiary care hospital of Bangladesh. A cross sectional study was conducted among eligible postpartum women at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka Bangladesh. Counseling was done about the procedure of PPIUCD in details.
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Sheetal Rudra Naik, Mamatha Tittamegalapalya Ramalingaiah, and Aishwarya Ram. "Study of clinical and etiological profile of hypertension in young patients." Asian Journal of Medical Sciences 16, no. 1 (2025): 49–54. https://doi.org/10.71152/ajms.v16i1.4358.

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Background: Hypertension significantly impacts global health, leading to coronary heart disease, stroke, and renal disease. Addressing it in young adults is crucial due to its potentially reversible causes and early intervention. Aims and Objectives: (1) To study the clinical profile of newly diagnosed hypertension in young patients (2) To study the etiological profile of hypertension in young. Materials and Methods: In this cross-sectional study after obtaining clearance from the institutional ethics committee, the patients fulfilling the inclusion criteria were enrolled after obtaining infor
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Yasin, Asma, Ayesha Azhar Khan, Asma Amin Baig, Madiha Afzal, Uzma Aziz, and Heema . "Acceptance of Post Placental IUCD Among Antenatal Patients." Pakistan Journal of Medical and Health Sciences 16, no. 4 (2022): 1133–35. http://dx.doi.org/10.53350/pjmhs221641133.

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Objective: To see the acceptance rate of PPIUCD among antenatal patients and compare it with international standards so that strategies to increase uptake of this contraceptive device can be devised especially for low compliance patients. Background : Post placental intrauterine contraceptive device ( PPIUCD) is the method of contraception that is effective immediately after delivery and patients don’t have to come back again from home. It is long acting, reversible, cost effective, free of systemic side effects and best for women with low compliance. Material and methods: This cross sectional
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G., Sruthi, Lalith Sundaram, Ranjakumar TC, Rahana Ashraf, and Nimesha Alex. "Central Corneal Thickness (CCT) Measurement in Each Trimester of Pregnancy: A Screening Parameter for a Healthy Eye During Pregnancy : A Prospective Study!" International Journal of Recent Surgical and Medical Sciences 01, no. 01 (2015): 019–25. http://dx.doi.org/10.1055/s-0039-1678628.

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AIM: - To detect central corneal thickness (CCT) in each trimester of pregnancy. Purpose: To evaluate difference in measurement of central corneal thickness due to corneal changes in each trimester of pregnancy. METHOD: - 100 healthy pregnant women within age group ranging from 21 to 35 years were included in the study. Central corneal thickness (Ultrasound Pachymetry), Intra ocular pressure (Goldmann-Applanation Tonometer) was done. Changes in central corneal thickness (CCT) were calculated at 3 time periods: First trimester, Second trimester, Third trimester. Informed consent was taken from
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Deshpande, Madhura Tinaikar, and Shashikala A. Sangle. "Clinical study of renal dysfunction in liver cirrhosis in a tertiary care hospital." Bharati Vidyapeeth Medical Journal 3, no. 4 (2023): 24–29. http://dx.doi.org/10.56136/bvmj/2023_01559.

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Background: Acute Kindney Injury (AKI) is a common complication of Liver Cirrhosis, and is reversible in its initial stage. AKI is seen in 20% of hospitalizations associated with complications related to liver dysfunction. The objective of the study was to study the clinical profile of patients with liver cirrhosis with renal dysfunction. Materials and Methods: This was a prospective observational study in diagnosed cases on liver cirrhosis in a tertiary care government hospital in Maharashtra. All the patients were screened for renal dysfunction using International Club of Ascites (ICA) AKI c
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Hu, Xichun, Jian Zhang, and Nicholas Patrick McAndrew. "Early clinical safety and pharmacokinetics data of DZD1516, an BBB-penetrant selective HER2 inhibitor for the treatment of HER2-positive metastatic breast cancer." Journal of Clinical Oncology 40, no. 16_suppl (2022): 1038. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.1038.

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1038 Background: Patients with HER2+ metastatic breast cancer (MBC) are at high risk of developing central nervous system metastases. DZD1516 is a reversible HER2-specific tyrosine kinase inhibitor (TKI) with full blood-brain barrier (BBB) penetration. Here we report the preliminary safety and PK data from the ongoing phase 1 study (NCT04509596) in patients with HER2+ MBC who relapsed from multiple prior treatments. Methods: Eligible patients received single oral dosing of DZD1516 on C0D1 and then twice daily (BID) oral dosing from C1D1 in a continuous 21-day cycle until disease progression, u
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Mane, Nupur S., and Jyoti V. Rokade. "Study the acceptance, compliance and efficacy of injection depot medroxy progesterone acetate as contraception: a prospective observational study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 1 (2020): 303. http://dx.doi.org/10.18203/2320-1770.ijrcog20205786.

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Background: India was the first country in the world to launch a family planning programme, as early as 1952, with the main aim of controlling its population. Depot medroxy progesterone acetate, or DMPA is a progestin-only method of contraception. It is a 3-monthly intramuscular injectable that delivers 150 mg of medroxyprogesterone acetate in microcrystalline suspension form that delays absorption of the hormone after the injection. It provides long acting, effective and reversible contraception. In this study, we evaluated patients in reproductive age group 18-35 years who were willing to us
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Benazir, Ansari, Sankar Murmu Sib, Pal Rajib, Dasgupta Mandira, and Kumar Hansda Subodh. "Profile of Acceptors and Outcome of Postpartum Intrauterine Contraceptive Device in a Tertiary Health Care Facility in West Bengal: A Prospective Observational Study." International Journal of Pharmaceutical and Clinical Research 14, no. 9 (2022): 290–300. https://doi.org/10.5281/zenodo.13324175.

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<strong>Background:&nbsp;</strong>In this study, we wanted to evaluate and analyse acceptance, effectiveness and complications of PPIUCD insertion in the postpartum period, assess the proportion of women accepting immediate PPIUCD insertion, find out the reasons for acceptance and decline of PPIUCD, find out the complications among the acceptors, follow post placental insertion and its outcome after 6 weeks, 3 months, and 6 months, evaluate the effectiveness of PPIUCD, and determine the reasons for removal of PPIUCD.&nbsp;<strong>Materials and Methods:&nbsp;</strong>This was a hospital based p
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Anderson, Douglas, and Azam Ahmed. "Treatment of patients with intractable obsessive—compulsive disorder with anterior capsular stimulation." Journal of Neurosurgery 98, no. 5 (2003): 1104–8. http://dx.doi.org/10.3171/jns.2003.98.5.1104.

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✓ Obsessive—compulsive disorder (OCD) is a common, chronic, disabling anxiety disorder characterized by recurrent obsessive thoughts and uncontrolled repetitive acts. Although many patients respond to various pharmacological treatments, there is a cohort of patients with intractable or refractory disease. The authors present the case of a patient with intractable OCD who was treated with bilateral electrical stimulators, which were stereotactically placed in the anterior limbs of the internal capsules. Following psychiatric consultation and 10 years of empirical medication regimens for OCD, a
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Ojha, Bidhata, Radha Baral, and Dipshikha Bajracharya. "ESTIMATION OF SALIVARY pH, BUFFERING CAPACITY, FLOW RATE, CARIES PREVALENCE AND ORAL MANIFESTATION IN CHRONIC RENAL FAILURE PATIENTS UNDERGOING DIALYSIS." Journal of Chitwan Medical College 10, no. 2 (2020): 19–24. http://dx.doi.org/10.54530/jcmc.139.

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Background: Renal failure is a process that expresses a loss of functional capacity of the nephrons, independently of its etiology. Although acute renal failure is reversible in the majority of cases, chronic renal failure presents a progressive course towards terminal renal failure. Hemodialysis is the most widely used technique leading to systemic alterations, oral complications and variations in the flow and composition of the saliva. The purpose of this study was to estimate salivary pH, buffering capacity, flow rate in chronic renal failure patients undergoing hemodialysis with its oral m
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Ojha, Bidhata, Radha Baral, and Dipshikha Bajracharya. "Estimation of salivary pH, buffering capacity, flow rate, caries prevalence and oral manifestation in chronic renal failure patients undergoing dialysis." Journal of Chitwan Medical College 10, no. 2 (2020): 19–24. http://dx.doi.org/10.3126/jcmc.v10i2.29663.

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Background: Renal failure is a process that expresses a loss of functional capacity of the nephrons, independently of its etiology. Although acute renal failure is reversible in the majority of cases, chronic renal failure presents a progressive course towards terminal renal failure. Hemodialysis is the most widely used technique leading to systemic alterations, oral complications and variations in the flow and composition of the saliva. The purpose of this study was to estimate salivary pH, buffering capacity, flow rate in chronic renal failure patients undergoing hemodialysis with its oral m
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Olubunmi Omotunde Onigbinde, Modupeore Ekua Sorunke, Olufemi O. Olagundoye, Folabi Oyapero, and Adenike Ololade Awotile. "The prevalence, perception, and behavior of self-reported gingival bleeding in two communities in Lagos state. Lagos. Nigeria." World Journal of Advanced Research and Reviews 24, no. 2 (2024): 033–43. http://dx.doi.org/10.30574/wjarr.2024.24.2.3298.

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Background: Periodontal disease is an inflammatory reaction that progresses from gingival inflammation (gingivitis) to loss of attachment, alveolar bone resorption, and eventual tooth loss. The earliest sign, gingival bleeding (GB) is often reported as bleeding while brushing and bleeding on probing (BOP) during clinical intraoral examination. Periodontal disease at this stage is completely reversible. Therefore, this cross-sectional survey assessed the prevalence and perception of self-reported gingival bleeding (SRGB) as well as oral hygiene practices of the studied population. Methodology:
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Mambally, Aparna, T. Udayakiren, Ravendra Kumar Tiwari, Hirpara Kishan MukeshBhai, and Arya S. Menon. "SUSTAINING LIFE WITH ACUTE KIDNEY INJURY; IMPACT OF AYURVEDIC STRATEGIES IN IMPROVING THE PATIENT RELATED OUTCOMES: A CASE REPORT." International Journal of Research in Ayurveda and Pharmacy 16, no. 2 (2025): 79–83. https://doi.org/10.7897/2277-4343.16248.

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Introduction: Declining of kidney function abruptly along with subsequent dysregulation of electrolytes, volume of urine and abnormal retention of nitrogenous wastes can lead to an acute kidney failure. Acute kidney failure can be reversible with medicines but chronic kidney failure is usually irreversible, with rate of mortality being very high. So only way is to extend the lifespan with medications, dialysis therapy or kidney transplant. This creates a lot of practical difficulties to the patient. Failure of kidney function is indicated by rise in serum creatinine, increase in urea and decre
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Vijayalakshmi, Gillella, Kavitha Kothapally, Uma Bhashyakarla, and Vasantha Kavati. "A prospective interventional study of intra-caesarean copper intrauterine contraceptive devices insertion in a teaching hospital in a rural medical college in Telangana, India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 4 (2020): 1470. http://dx.doi.org/10.18203/2320-1770.ijrcog20201207.

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Background: Providing quality contraceptive services to women is essential for achieving maternal and child health. Objective of this study was to evaluate the efficacy of intra-caesarean insertion of copper IUCDs as postpartum contraception. To study the side effects of intra caesarean copper device. To study the continuation rates of intra-caesarean copper IUCDs. To study the acceptability of intra-caesarean copper IUCD as immediate postpartum contraceptive.Methods: The prospective study was undertaken at Bhaskar medical college and general hospital, Yenkepally, Moinabad, Telangana, between
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A R, Rachana, Malatesh Undi, Latha K G, and Swetha K. "A Study To Assess The Perception, Acceptance And Satisfaction Regarding Postpartum Intra Uterine Contraceptive Device Services In A Tertiary Care Hospital In A Coastal District Of Karnataka." Indian Journal of Public Health Research & Development 15, no. 1 (2024): 348–55. https://doi.org/10.37506/y72dhm51.

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Introduction Unintended pregnancy is an important public health issue in developing countries like India because of its association with adverse social and health outcomes. Family planning enables women to achieve healthy spacing between births and reduces maternal and child mortality by 10%. Intra Uterine Contraceptive Device (IUCD) is effective immediately after insertion and provides very effective, safe and long-term –yet reversible protection from pregnancy. Postpartum IUCD insertion has a higher rate of retention. Objective To assess the perception, acceptance and satisfaction regarding
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DeRenzo, Evan. "Surrogate Decision Making for Severely Cognitively Impaired Research Subjects: The Continuing Debate." Cambridge Quarterly of Healthcare Ethics 3, no. 4 (1994): 539–48. http://dx.doi.org/10.1017/s0963180100005429.

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As research into Alzheimer's disease and other dementing disorders becomes more complex, risky, invasive, and commonplace, the need intensifies for discussion of the ethics of involving persons with dementia in research, specifically research of greater than minimal risk and of no expected direct benefit to the subject. (It is beyond the scope of this paper to consider the ethical issues related to research involvement of cognitively impaired children or children or adults with intermittent and/or reversible cognitive or psychiatric impairments. For such discussions, refer to the references in
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Budman, D. R., N. J. Meropol, B. Reigner, et al. "Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabine." Journal of Clinical Oncology 16, no. 5 (1998): 1795–802. http://dx.doi.org/10.1200/jco.1998.16.5.1795.

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PURPOSE To evaluate the toxicology and pharmacology of an orally active fluoropyrimidine given as a continuous daily dose divided into two portions for 6 weeks, and to determine the maximal-tolerated daily dose (MTD) and the suggested phase II daily dose. PATIENTS AND METHODS Solid-tumor patients with a Karnofsky performance status greater than 70 who had normal organ function and resolution of the effects of prior therapy, and who gave informed written consent, were enrolled. Oral capecitabine, as a divided morning and evening dose, was administered to cohorts of a minimum of 3 patients start
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Ashraf, Shazia, Munazzah Bashir, and Rubina Tazayyen Yousaf. "In A Tertiary Care Hospital, the Use of A Postpartum Intrauterine Contraceptive Device as A Method of Contraception." Pakistan Journal of Medical and Health Sciences 16, no. 11 (2022): 667–69. http://dx.doi.org/10.53350/pjmhs20221611667.

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Objective: Aim was to assess the acceptability, safety, and efficacy of a post-partum intrauterine contraceptive device among patients. Study Design: Prospective observational study Place and Duration: AIMC / Jinnah Hospital, Lahore for the duration from January 2022 to August 2022. Methods: Total 190 pregnant women of age 18-42 years were presented in this study. After receiving informed written consent, gestational age, BMI, parity, socioeconomic status, and age were determined. All the patients received postpartum intrauterine contraceptive device (PPIUCD) either of normal vaginal delivery
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Zahid, Muhammad, Alamzeb Khan Jadoon, Dur e. Shehwar Ali, Shah Nawaz, Seema Ali, and Ayesha Khan. "The nightmare of impaired fasting glucose in young adults: a cross-sectional study." Journal of Rehman Medical Institute 10, no. 4 (2025): 07–09. https://doi.org/10.52442/jrmi.v10i4.893.

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Introduction: Prediabetes, a precursor of frank Diabetes Mellitus, can be diagnosed before it gives rise to the actual disease condition if a screening strategy is adopted in young adults. Once diagnosed, lifestyle modifications can make prediabetes reversible thereby preventing the morbidity and mortality associated with frank Diabetes Mellitus. Objective: To determine the prevalence of impaired fasting glucose (IFG), a precursor to type 2 diabetes, among young adults (aged 17–24 years) at Nowshera Medical College, Nowshera. Materials &amp; Methods: A cross-sectional descriptive study was con
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Olubunmi, Omotunde Onigbinde, Ekua Sorunke Modupeore, O. Olagundoye Olufemi, Oyapero Folabi, and Ololade Awotile Adenike. "The prevalence, perception, and behavior of self-reported gingival bleeding in two communities in Lagos state. Lagos. Nigeria." World Journal of Advanced Research and Reviews 24, no. 2 (2024): 033–43. https://doi.org/10.5281/zenodo.15067590.

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<strong>Background:</strong>&nbsp;Periodontal disease is an inflammatory reaction that progresses from gingival inflammation (gingivitis) to loss of attachment, alveolar bone resorption, and eventual tooth loss. The earliest sign, gingival bleeding (GB) is&nbsp;often reported as bleeding while brushing and bleeding on probing (BOP) during clinical intraoral examination. Periodontal disease at this stage is completely reversible. Therefore, this cross-sectional survey assessed the prevalence and perception of self-reported gingival bleeding (SRGB) as well as oral hygiene practices of the studie
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Beg, Ahsan, Abdul Malik, Amjad Mahmood, M. Younas, and Fakher e. Fayaz. "DECISION MAKING FOR DEVICE CLOSURE IN ADULTS WITH ‘HYPERTENSIVE PDA’–NON-INVASIVE CRITERIA: IMMEDIATE RESULTS." Pakistan Armed Forces Medical Journal 70, Suppl-4 (2021): S762–67. http://dx.doi.org/10.51253/pafmj.v70isuppl-4.6020.

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Objective: To find the mean pulmonary artery pressures (PAP) in adults (&gt;12 years) Patent Ductus Arteriosus (PDA) with ‘reversible pulmonary hypertension’ after the device closure. Residual PDA and immediate complications (embolization, pulse loss, obstruction in the aorta or pulmonary artery) are to be reported.&#x0D; Study Design: Retrospective study.&#x0D; Place and Duration of Study: Tertiary Care Referral Hospital, from Aug 2007 to Jun 2020.&#x0D; Methodology: This retrospective study is descriptive. Data collected by convenience sampling from 3 tertiary care referral hospital. 981 pat
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