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1

Dhungel, Alok, Tariq Wassem, and Kshitiz Upadhyay-Dhungel. "Diabetic: A Comparative Study." Janaki Medical College Journal of Medical Science 4, no. 1 (2017): 19–26. http://dx.doi.org/10.3126/jmcjms.v4i1.16381.

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Background and Objectives: Type II diabetes mellitus (DM) is particularly common medical disorder and is leading cause of morbidity worldwide. The complication of DM is due to micro or macro vascular damage. The presence of an extensive microvascular circulation and abundant connective tissue in the lungs raises the possibility that lung tissue may be a target organ in diabetic patients and thus pulmonary function test can be affected by DM. This study was designed to compare pulmonary function test between Type II diabetic and non-diabetic individuals; and, with the duration of DM.Material and Methods: This cross sectional comparative study was conducted at King Edward Medical University, Lahore Pakistan. Total sample consist of 91 diabetic and 91 non-diabetic grouped as group A and group B. FEV1, FVC, FEV1/FVC ratio, and PEFR were compared within two groups and with the duration of DM.Results: Total 182 sample with mean age 53.1±5.90 years, with 91(50%) male and 91(50%) female. Group A and B had 91(50%) sample each. Mean value of FVC, FEV1 and PEFR showed statistically significant difference among the both group. Mean of FVC decreases significantly with the increasing duration of DM; although, is not significant with FEV1, FEV1/FVC ratio, and PEFR.Conclusion: Diabetic group showed significantly impaired pulmonary functions test as FEV1, FVC, and PEFR as compare to non-diabetic group.Janaki Medical College Journal of Medical Sciences (2016) Vol. 4 (1): 19-26
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2

Beecher, Donald, Christopher Marlowe, and Richard Rowland. "Edward II." Sixteenth Century Journal 27, no. 2 (1996): 583. http://dx.doi.org/10.2307/2544213.

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3

Pencak, William. "Edward II." American Journal of Semiotics 11, no. 3 (1994): 203–21. http://dx.doi.org/10.5840/ajs1994113/413.

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4

Prasch, Thomas, Steve Clark-Hall, Antony Root, Derek Jarman, Ken Butler, and Stephen McBride. "Edward II." American Historical Review 98, no. 4 (1993): 1164. http://dx.doi.org/10.2307/2166608.

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5

Kruger, Loren, and Bertolt Brecht. "Edward II." Theatre Journal 40, no. 3 (1988): 413. http://dx.doi.org/10.2307/3208335.

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6

Anderson, Randall Louis, and Christopher Marlowe. "Edward II." Theatre Journal 45, no. 1 (1993): 106. http://dx.doi.org/10.2307/3208590.

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7

Sequera, Hector. "Reconstructing William Byrd’s consort songs from the Paston lutebooks: a historically informed and computational approach to comparative analysis and musical idiom." Early Music 47, no. 4 (2019): 455–77. http://dx.doi.org/10.1093/em/caz069.

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Abstract This article outlines how computational analysis can be applied to the process of making and evaluating idiomatic reconstructions of polyphonic music from lute intabulations. It focuses on some of William Byrd’s consort songs that survive only as intabulations in one of the lute books owned by Edward Paston (1550–1630), London, British Library, Add. Ms. 31992. Fourteen of the consort songs survive as intabulations and full settings, and form the corpus used in this study; 15 survive only as intabulations needing reconstruction to return them to a performable state. After discussing the context of the pieces, the article presents three analyses: (1) to establish the differences between the tablatures and the full settings, (2) to study more closely these differences in order to inform reconstruction work, and (3) to evaluate three separate reconstructions of Byrd’s ‘In tower most high’ using the corpus and the data collected.
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8

Cervo, Nathan A. "Marlowe's Edward II." Explicator 58, no. 3 (2000): 123–24. http://dx.doi.org/10.1080/00144940009595957.

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9

Harcourt, Edward. "II—Edward Harcourt." Aristotelian Society Supplementary Volume 78, no. 1 (2004): 111–29. http://dx.doi.org/10.1111/j.0309-7013.2004.00118.x.

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10

Callens, Johan. "Edward II (review)." Theatre Journal 64, no. 4 (2012): 601–3. http://dx.doi.org/10.1353/tj.2012.a494455.

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11

Aleva, Maarten. "Edward II en Richard II." Madoc 33, no. 2 (2019): 108–16. http://dx.doi.org/10.5117/madoc2019.2.005.alev.

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12

Cho, Jaehee. "Edward II : Oedipal Tragedy." NEW STUDIES OF ENGLISH LANGUAGE & LITERATURE 77 (November 30, 2020): 225–45. http://dx.doi.org/10.21087/nsell.2020.11.77.225.

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13

Smith, Alan. "Marlowe’s Edward II, 5.3.23." Explicator 52, no. 2 (1994): 66–69. http://dx.doi.org/10.1080/00144940.1994.11484095.

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14

Cochrane, Claire. "The Theatre: Edward II." Cahiers Élisabéthains: A Journal of English Renaissance Studies 32, no. 1 (1987): 85–86. http://dx.doi.org/10.1177/018476788703200113.

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15

Smith, Peter J. "Review: Play: Edward II." Cahiers Élisabéthains: A Journal of English Renaissance Studies 48, no. 1 (1995): 96–98. http://dx.doi.org/10.1177/018476789504800117.

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16

Peterson, Kaara L. "Play review: Edward II." Cahiers Élisabéthains: A Journal of English Renaissance Studies 94, no. 1 (2017): 136–39. http://dx.doi.org/10.1177/0184767817728907k.

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17

Smith, Peter J. "Play review: Edward II." Cahiers Élisabéthains: A Journal of English Renaissance Studies 100, no. 1 (2019): 132–34. http://dx.doi.org/10.1177/0184767819868166d.

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18

Hamilton, J. S. "England under Edward I and Edward II, 1259–1327." History: Reviews of New Books 29, no. 2 (2001): 68–69. http://dx.doi.org/10.1080/03612759.2001.10525758.

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19

Gillespie, James L., and Sandra Raban. "England under Edward I and Edward II 1259-1327." Albion: A Quarterly Journal Concerned with British Studies 33, no. 4 (2001): 623. http://dx.doi.org/10.2307/4052900.

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20

Rachel Evans. "Edward II (review)." Theatre Journal 60, no. 3 (2008): 482–84. http://dx.doi.org/10.1353/tj.0.0066.

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21

Hamilton, J. S. "Edward II, by Seymour Phillips." English Historical Review CXXVI, no. 520 (2011): 655–57. http://dx.doi.org/10.1093/ehr/cer107.

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22

McCLOSKEY, SUSAN. "The Worlds of "Edward II"." Renaissance Drama 16 (January 1985): 35–48. http://dx.doi.org/10.1086/rd.16.41920156.

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23

SCHOFIELD, PHILLIPP R. "Edward II - By Seymour Phillips." History 96, no. 324 (2011): 500. http://dx.doi.org/10.1111/j.1468-229x.2011.00531_7.x.

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24

Byung-Eun Lee. "The Aristocracy in Edward II." Medieval and Early Modern English Studies 16, no. 2 (2008): 311–27. http://dx.doi.org/10.17054/memes.2008.16.2.311.

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25

Stevens, Andrea. "Edward II (review)." Shakespeare Bulletin 27, no. 1 (2009): 117–22. http://dx.doi.org/10.1353/shb.0.0055.

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26

Cronin, Graeme. "England under Edward I and Edward II (review)." Parergon 19, no. 1 (2002): 295. http://dx.doi.org/10.1353/pgn.2002.0098.

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27

GIVEN-WILSON, C. "Richard II, Edward II, and the Lancastrian Inheritance." English Historical Review CIX, no. 432 (1994): 553–71. http://dx.doi.org/10.1093/ehr/cix.432.553.

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28

Dyer, Christopher. "England under Edward I and Edward II, 1259-1327. Sandra Raban." Speculum 78, no. 1 (2003): 250. http://dx.doi.org/10.1017/s0038713400099735.

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29

KangSeokJu. "Edward II: Homoeroticism and Political Desire." English21 29, no. 4 (2016): 5–32. http://dx.doi.org/10.35771/engdoi.2016.29.4.001.

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30

Ivic, Christopher. "Republican Reimaginings in Marlowe’s Edward II." Humanities 11, no. 1 (2022): 23. http://dx.doi.org/10.3390/h11010023.

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This essay explores the intersection of republican and nationalist ideas in Marlowe’s Elizabethan history play Edward II. I read the play less in terms of recent dominant readings: that is, focussing on the same-sex relation between King Edward and his ‘minion’ Gaveston. Instead, I focus on the play’s critique of Edward’s authoritarian and arbitrary rule, a critique of monarchy informed by proto-republican ideology and a nascent nationalism. This essay also considers the play’s archipelagic angles within the context of the play’s initial inscription—Queen Elizabeth’s two-kingdom, three-nation rule—as well as its Jacobean publications.
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31

Palmer, Bryan D. "Homage to Edward Thompson, Part II." Labour / Le Travail 33 (1994): 13. http://dx.doi.org/10.2307/25143788.

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32

SULLIVAN, CERI. "MARLOWE'S EDWARD II AND RECUSANT PHRASING." Notes and Queries 41, no. 4 (1994): 451—a—451. http://dx.doi.org/10.1093/nq/41-4-451a.

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33

BRACKETT, VIRGINIA. "ELIZABETH CARY, DRAYTON, AND EDWARD II." Notes and Queries 41, no. 4 (1994): 517—b—519. http://dx.doi.org/10.1093/nq/41-4-517b.

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34

Hamilton, J. S. "The Uncertain Death of Edward II?" History Compass 6, no. 5 (2008): 1264–78. http://dx.doi.org/10.1111/j.1478-0542.2008.00549.x.

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35

TALVACCHIA, B. "Historical Phallicy: Derek Jarman's Edward II." Oxford Art Journal 16, no. 1 (1993): 112–28. http://dx.doi.org/10.1093/oxartj/16.1.112.

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36

Kelly, William B. "Mapping Subjects in Marlowe's "Edward II"." South Atlantic Review 63, no. 1 (1998): 1. http://dx.doi.org/10.2307/3201388.

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37

Zhang, Tian, Thomas Weart, Matthias Weiss, et al. "Abstract CT055: PAVO: A phase-II, open label, single arm study of niraparib in patients with locally advanced/metastatic PALB2 mutated tumors." Cancer Research 83, no. 8_Supplement (2023): CT055. http://dx.doi.org/10.1158/1538-7445.am2023-ct055.

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Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPi) have demonstrated efficacy in treating solid tumors with Homologous Recombination Deficiency (HRD), the inability to repair DNA double-stranded breaks through the Homologous Recombination Repair (HRR) pathway. Specific genetic and epigenetic alterations result in defective HRR function. Bi-allelic loss of BRCA1 or BRCA2 principally drives HRR deficiency. While BRCA1/2 are instrumental to HRR, multiple genes, including PALB2, impact the HRR pathway. PALB2 mutations occur in an estimated 0.97% to 3.66% of solid tumors [AACR GENIE PALB2] and are associated with susceptibility to various cancers. No clinically approved therapies specifically targeting PALB2 currently exist. Emerging evidence suggests that patients with germline or somatic PALB2 mutations may benefit from PARPi treatment, which has potential to be a new tumor agnostic therapy option across a wide range of solid tumors. Methods PAVO is a pan-tumor, single-arm, multicenter Phase-II study assessing the safety and efficacy of niraparib (a PARPi) in patients who harbor a confirmed PALB2 mutation. The study plans to enroll up to 110 adult subjects. Eligible participants must have: locally advanced or metastatic solid tumor(s); confirmed pathogenic or likely pathogenic somatic or germline PALB2 mutation; received all standard of care (SOC) therapy for their tumor type, or are unlikely to derive benefit from SOC therapy in the opinion of the treating physician; ECOG performance status of 0 or 1; life expectancy of ≥ 12 weeks with adequate organ/bone marrow function. Exclusion criteria include a confirmed somatic or germline BRCA1/2 mutation, prior treatment with any PARPi, ovarian or prostate cancer, or rapid progression while on platinum-based therapy in the metastatic setting. Niraparib will be administered in 28 day cycles with daily dosing, as outlined in the protocol. Participants will continue study treatment until documented radiographic progression, unacceptable toxicity, death, or consent withdrawal. The primary study endpoint is objective response rate (ORR), defined as the proportion of participants who have partial or complete response to therapy as assessed by Independent Central Review. Secondary endpoints include DOR, PFS, and CBR. PAVO is sponsored by Tempus with support from GSK (GlaxoSmithKline). The trial opened in March 2022. Tempus molecular data tracking (integrated NGS and EMR data) and the TIME Trial program (rapid match of patients to Just in TIME sites for clinical trials), enable patient identification and prescreening. Enrollment occurs through a combination of TIME and prospective clinical sites, where individualized prescreening models are in development. New site identification and referral of molecularly eligible patients to enrolling centers are ongoing. Clinical Trial Registry: NCT05169437 Citation Format: Tian Zhang, Thomas Weart, Matthias Weiss, Drew Murray, Minaxi Jhawer, Edward Huynh, Shumei Kato, Amy Cummings, Lydia Usha, Arvinder Bhinder, Rajiv Desai, Brad Johnson, Anjali Avadhani, Cecile Rose T. Vibat, Lauren Lopez, Brynna Driscoll, Annajane Ward, Christie K. Rice, Blathnaid Donovan, Scott Sherrin, Mykel Robble, Stephanie O'Leary, Kimberly Blackwell, Amine Aziez, Stephanie Petrone, Kathleen Harnden, Kimberly Strickland, Sonya Reid, Mark Robson, Andrew S. Paulson, Afshin Dowlati. PAVO: A phase-II, open label, single arm study of niraparib in patients with locally advanced/metastatic PALB2 mutated tumors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 2 (Clinical Trials and Late-Breaking Research); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(8_Suppl):Abstract nr CT055.
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38

Rikos, Dimitrios, Michail Vikelis, Emmanouil V. Dermitzakis, et al. "Reporting Quality and Risk of Bias Analysis of Published RCTs Assessing Anti-CGRP Monoclonal Antibodies in Migraine Prophylaxis: A Systematic Review." Journal of Clinical Medicine 13, no. 7 (2024): 1964. http://dx.doi.org/10.3390/jcm13071964.

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Objective: Phase II/III randomized clinical trials (RCTs) are vulnerable to many types of bias beyond randomization. Insights into the reporting quality of RCTs involving migraine patients treated with monoclonal antibodies targeting the calcitonin gene-related peptide system (anti-CGRP MAbs) are currently lacking. Our aim was to analyze the reporting quality of phase II/III RCTs involving migraine patients treated with anti-CGRP MAbs. Methods: A systematic search was performed on the PubMed and EMBASE databases, according to PRISMA guidelines, for relevant RCTs in either episodic or chronic migraine prevention. Additionally, an adapted version of the 2010 CONSORT statement checklist was utilized. The ROBvis online tool was used to document the risk of bias. Results: From the initially identified 179 articles, we finally found 31 RCTs that were eligible for evaluation. The average CONSORT compliance was 88.7% (69.7–100%), while 93.5% (N = 29) of the articles had a compliance greater than 75%. Twenty-eight CONSORT items were reported in more than 75% of the articles. The average compliance of the analyzed RCTs was 93.9% for Galcanezumab, 91.3% for Fremanezumab, followed by 85.4% for Erenumab and Eptinezumab studies. Implementation of the ROB2 tool showed some concerning “missing information” arising from the inadequate reporting. Specifically, 50% of the studies (N = 16) were categorized as having inadequate information regarding the randomization process. Conclusions: Adequate reporting quality was disclosed in the evaluated RCTs with anti-CGRP MAbs in migraine prevention. However, some methodological issues need to be highlighted to be addressed in future studies assessing the efficacy of new molecules targeting CGRP or other candidate pathways implicated in migraine pathophysiology.
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39

Li, Jing-Yi, Yuan-Fen Zhang, Gordon S. Smith, et al. "Quality of Reporting of Randomized Clinical Trials in Tai Chi Interventions—A Systematic Review." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–10. http://dx.doi.org/10.1093/ecam/nep022.

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Objectives. To evaluate the reporting quality of published randomized clinical trials (RCTs) in the Tai Chi literature following the publication of the CONSORT guidelines in 2001.Data Sources. The OVID MEDLINE and PUBMED databases.Review Methods. To survey the general characteristics of Tai Chi RCTs in the literature, we included any report if (i) it was an original report of the trial; (ii) its design was RCT; (iii) one of the treatments being tested was Tai Chi; and (iv) it was in English. In addition, we assessed the reporting quality of RCTs that were published between 2002 and 2007, using a modified CONSORT checklist of 40 items. The adequate description of Tai Chi interventions in these trials was examined against a 10-item checklist adapted from previous reviews.Results. The search yielded 31 Tai Chi RCTs published from 2002 to 2007 and only 11 for 1992–2001. Among trials published during 2002–2007, the most adequately reported criteria were related to background, participant eligibility and interpretation of the study results. Nonetheless, the most poorly reported items were associated with randomization allocation concealment, implementation of randomization and the definitions of period of recruitment and follow-up. In addition, only 23% of RCTs provided adequate details of Tai Chi intervention used in the trials.Conclusion. The findings in this review indicated that the reporting quality of Tai Chi intervention trials is sub-optimal. Substantial improvement is required to meet the CONSORT guidelines and allow assessment of the quality of evidence. We believe that not only investigators, but also journal editors, reviewers and funding agencies need to follow the CONSORT guidelines to improve the standards of research and strengthen the evidence base for Tai Chi and for complementary and alternative medicine.
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40

김성환. "Homosexuality/Sodomy and Politics in Edward II and Richard II." Shakespeare Review 49, no. 1 (2013): 5–31. http://dx.doi.org/10.17009/shakes.2013.49.1.001.

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41

Mitchell, Shelagh. "Ladies of the Garter: Edward III; Richard II; Elizabeth II." Court Historian 22, no. 2 (2017): 151–67. http://dx.doi.org/10.1080/14629712.2017.1388705.

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42

Buck, Mark. "Roy M. Haines, King Edward II (2003)." Nottingham Medieval Studies 48 (January 2004): 256–59. http://dx.doi.org/10.1484/j.nms.3.370.

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43

Maddicott, J. R. "The Reign of Edward II: New Perspectives." English Historical Review CXXIII, no. 500 (2008): 176–78. http://dx.doi.org/10.1093/ehr/cem406.

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44

BENNETT, KATE. "BALDOCK'S ’GENTRIE‘: SOCIAL CLIMBING IN EDWARD II." Notes and Queries 44, no. 4 (1997): 483—b—484. http://dx.doi.org/10.1093/nq/44.4.483-b.

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45

Rutkoski, Marie. "Breeching the Boy in Marlowe's Edward II." SEL Studies in English Literature 1500-1900 46, no. 2 (2006): 281–304. http://dx.doi.org/10.1353/sel.2006.0020.

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46

Bennett, K. "Baldock's 'Gentrie': Social Climbing in Edward II." Notes and Queries 44, no. 4 (1997): 483–84. http://dx.doi.org/10.1093/notesj/44.4.483-a.

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47

Shaltz, Justin. "Edward II, and: Measure for Measure (review)." Shakespeare Bulletin 24, no. 1 (2006): 89–96. http://dx.doi.org/10.1353/shb.2006.0019.

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48

Hull, Helen, and Kirk Melnikoff. "Edward II by The American Shakespeare Center." Shakespeare Bulletin 33, no. 2 (2015): 365–69. http://dx.doi.org/10.1353/shb.2015.0032.

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49

VALENTE, C. "The Deposition and Abdication of Edward II." English Historical Review CXIII, no. 453 (1998): 852–81. http://dx.doi.org/10.1093/ehr/cxiii.453.852.

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50

Guy-Bray, Stephen. "Homophobia and the Depoliticizing of Edward II." ESC: English Studies in Canada 17, no. 2 (1991): 125–33. http://dx.doi.org/10.1353/esc.1991.0025.

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