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1

Sterckx, Sigrid, Kasper Raus, and Freddy Mortier, eds. Continuous Sedation at the End of Life. Cambridge University Press, 2013. http://dx.doi.org/10.1017/cbo9781139856652.

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2

Urman, Richard D., and Alan D. Kaye, eds. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2012. http://dx.doi.org/10.1017/cbo9781139084000.

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3

Malamed, Stanley F. Sedation: A guide to patient management. 3rd ed. Mosby, 1995.

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4

G, Reves J., and Sladen Robert N, eds. Anesthesia and sedation by continuous infusion: Proceedings of a symposium, May 31-June 1, 1991. Excerpta Medica, 1992.

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5

L, Quinn Christine, ed. Sedation: A guide to patient management. 2nd ed. Mosby, 1989.

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6

Favaro, Alice. Después de la caída del ‘ángel’. Edizioni Ca' Foscari, 2020. http://dx.doi.org/10.30687/978-88-6969-416-5.

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Ángel Bonomini was born in Buenos Aires in 1929 where he lived until his death at the age of sixty-four in 1994. He worked for various newspapers and magazines as an art critic and translator, but always maintaining his literary activity. He inherited the tradition of the Argentine fantastic and was a prolific writer: his production includes essays, poems and fantastic tales.Although he lived in a period of great cultural splendor and his literary talent was recognised by authors such as Borges and Bioy Casares, he fell into an unexplained oblivion, disappearing quite early from the contempora
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7

Gross. Moderate And Deep Sedation. Not Avail, 2006.

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8

Sterckx, Sigrid, and Kasper Raus. Continuous Sedation at the End of Life. Edited by Stuart J. Youngner and Robert M. Arnold. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199974412.013.7.

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This chapter examines continuous sedation as a way to relieve unbearable suffering in patients at the end of life. After considering consensus and guidelines on continuous sedation, it looks at the debate over terminology and definition. It then discusses the practice of continuous sedation in various countries and how it is performed, along with the importance of patient consent and autonomy in all sedation guidelines. The chapter goes on to analyze some of the commonly invoked justifications for continuous sedation, including the doctrine of double effect, last resort and refractory sufferin
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9

Urman, Richard D., and Alan D. Kaye. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2012.

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10

Kaye, Alan David, and Richard D. Urman. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2017.

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11

Kaye, Alan David, and Richard D. Urman. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2017.

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12

Urman, Richard D., and Alan David Kaye, eds. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2017. http://dx.doi.org/10.1017/9781316796016.

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13

Urman, Richard D., and Alan D. Kaye. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2012.

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14

Urman, Richard D., and Alan D. Kaye. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2012.

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15

Urman, Richard D., and Alan D. Kaye. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2012.

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16

Kaye, Alan David, and Richard D. Urman. Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2017.

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17

Moderate and deep sedation in clinical practice. Cambridge University Press, 2012.

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18

Moderate and Deep Sedation in Clinical Practice. Cambridge University Press, 2024.

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19

Association, American Dental, ed. Guidelines for the use of conscious sedation, deep sedation and general anesthesia for dentists. 1997.

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20

Knape, Johannes (Hans) T. A. Conscious sedation. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0050.

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After a thorough introduction to conscious sedation, including the reasons for the increase in demand for assistance for moderate (conscious)-to-deep sedation in medicine over recent decades, this chapter covers some key definitions, before moving on to morbidity, mortality, and safety. The chapter then discusses how to prepare the patient for sedation, including the issue of whether the patient should have fasted prior to sedation and the screening of patients for sedation. It looks at the necessary qualifications and responsibilities of a sedation practitioner, and the monitoring of patients
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21

Macauley, Robert C. Palliative Sedation (DRAFT). Edited by Robert C. Macauley. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199313945.003.0009.

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Palliative sedation refers to lowering a patient’s level of consciousness so that she no longer suffers from intolerable and refractory symptoms. Some forms of palliative sedation are ethically uncontroversial, such as emergency or respite sedation. Continuous sedation to unconsciousness (CSU) is controversial in that a patient in such a state is unable to eat or drink and may not be able to protect her airway. Ethically relevant considerations include the inability to participate in subsequent decision-making, the uncertain quality of an unconscious life, and the impact on life expectancy (wh
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22

Continuous Sedation at the End of Life: Ethical, Clinical and Legal Perspectives. Cambridge University Press, 2013.

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23

Sterckx, Sigrid, Freddy Mortier, and Kasper Raus. Continuous Sedation at the End of Life: Ethical, Clinical and Legal Perspectives. Cambridge University Press, 2013.

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24

Sterckx, Sigrid, Freddy Mortier, and Kasper Raus. Continuous Sedation at the End of Life: Ethical, Clinical and Legal Perspectives. Cambridge University Press, 2013.

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25

Sterckx, Sigrid, Freddy Mortier, and Kasper Raus. Continuous Sedation at the End of Life: Ethical, Clinical and Legal Perspectives. Cambridge University Press, 2016.

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26

Asin, Melvin. The Behaviour of Reinforced Concrete Continuous Deep Beams. Delft Univ Pr, 2000.

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27

Malamed, Stanley F. Sedation: A guide to patient management. 2nd ed. Mosby, 1988.

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28

Quinn, Christine L., and Stanley F. Malamed. Sedation: A Guide to Patient Management. 3rd ed. Mosby-Year Book, 1995.

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29

Sury, Michael. Procedural sedation in children. Edited by Jonathan G. Hardman and Neil S. Morton. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0072.

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Sedation is a state of reduced consciousness in which the patient should be rousable. The main concern is that sedation can become too deep, unintentionally, and the patient can be harmed. The practitioner must therefore be trained to cope with all the common side-effects of sedation. Sedation techniques depend on the intended procedure. Four common scenarios are covered in this chapter: painless imaging, painful procedures, endoscopy, and dental procedures. Each of these has specific demands and they are discussed in detail. The anaesthetist should choose short-acting potent drugs to provide
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30

Sedation: A guide to patient management. 5th ed. Mosby Elsevier, 2010.

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31

Sedation: A Guide to Patient Management. 4th ed. Mosby, 2002.

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32

Exhaust ventilation of deep cuts using a continuous-mining machine. U.S. Dept. of the Interior, Bureau of Mines, 1985.

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33

Mistraletti, Giovanni, and Gaetano Iapichino. Sedation assessment in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0358.

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Patient comfort is a primary goal in ICU, but achieving and maintaining the appropriate balance of analgesia, sedation, and treatment of delirium is frequently challenging. International guidelines recommend keeping critically-ill patients calm and cooperative, awake in daytime and asleep at night, always avoiding deep sedation. To state the actual level of sedation and the desired one, it is necessary to frequently perform a sedation assessment with validated tools. Subjective methods are the most useful guides in ICU consciously-sedated patients, representing the gold standard for good clini
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34

Krakauer, Eric L. Sedation at the end of life. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0182.

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Palliative sedation is a well-accepted therapy that should be considered in the rare situations when a terminally ill patient whose overriding goal is comfort experiences severe suffering that is refractory to all available standard palliative interventions. Typically, such suffering is caused by physical or neuropsychiatric symptoms such as pain, dyspnoea, vomiting, seizures, agitated delirium, anxiety, or depression. The level of sedation should be proportional to an individual patient’s suffering and should be just deep enough to provide the desired relief. In some cases, sedation to uncons
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35

Lacombe, Gabriel F. Comparison of remifentanil infusion with fentanyl for use with propofol for deep sedation in oral surgery. 2003.

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36

Sessler, Curtis N., and Katie M. Muzevich. Sedatives and anti-anxiety agents in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0042.

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Sedative and anti-anxiety agents are administered to many mechanically-ventilated intensive care unit (ICU) patients. While commonly considered supportive care, suboptimal administration of sedatives has been linked to longer duration of mechanical ventilation and longer ICU length of stay. The use of a structured multidisciplinary approach can help improve outcomes. The level of consciousness, as well as the presence and severity of agitation should be routinely evaluated using a validated sedation–agitation scale. The approach to delivery of sedation should be based upon specific goals, part
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37

Assessment of deep conventional and continuous-type (unconventional) natural gas plays in the United States. U.S. Dept. of the Interior, U.S. Geological Survey, 1996.

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38

Metzner, Julia, and Karen B. Domino. Outcomes, Regulation, and Quality Improvement. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190495756.003.0010.

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To improve the safety of patients undergoing procedures in remote locations, practitioners should be familiar with rigorous continuous quality improvement systems, national and regulatory patient safety efforts, as well as complications related to anesthesia/sedation in out of the operating room (OOOR) settings. This chapter discusses severe outcomes and mechanisms of injury in OOOR locations, national patient safety and regulatory efforts that may be adapted to the OOOR setting, and quality improvement efforts essential to track outcomes and improve patient safety. Patient safety can be impro
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39

Vespa, Paul M. Electroencephalogram monitoring in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0221.

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Electroencephalography monitoring provides a method for monitoring brain function, which can complement other forms of monitoring, such as monitoring of intracranial pressure and derived parameters, such as cerebral perfusion pressure. Continuous electroencephalogram (EEG) monitoring can be helpful in seizure detection after brain injury and coma. Seizures can be detected by visual inspection of the raw EEG and/or processed EEG data. Treatment of status epilepticus can be improved by rapid identification and abolition of seizures using continuous EEG. Quantitative EEG can also be used to detec
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40

Schmidt, Gregory A., and Kevin Doerschug. Promoting physical recovery in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0378.

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Survivors of critical illnesses are often faced with persistent neuromuscular weakness that interferes with daily activities. Advancements in survival from critical illness have led to a rise in the number of patients afflicted with post-intensive care unit (ICU) incapacity. It is clear that the pathology leading to ICU-acquired weakness is present within 24 hours of the start of ICU care. Care-givers must consider interventions to limit or reverse these processes from the onset of critical illness. We suggest strategies both for avoiding harms and for actively promoting recovery of skeletal a
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41

Youngner, Stuart J., and Robert M. Arnold. Introduction. Edited by Stuart J. Youngner and Robert M. Arnold. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199974412.013.30.

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This volume explores the topic of death and dying from the late twentieth to the early twenty-first centuries, with particular emphasis on the United States. The book comprises six sections. Section I examines how the law has helped shape clinical practice, emphasizing the roles of rights and patient autonomy. Section II focuses on specific clinical issues, including death and dying in children, continuous sedation as a way to relieve suffering at the end of life, and the problem of prognostication in patients who are thought to be dying. Section III considers psychosocial and cultural issues,
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42

Dodds, Chris, Chandra M. Kumar, and Frédérique Servin. Anaesthesia for orthopaedic surgery in the elderly. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198735571.003.0007.

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Arthritis and falls are common in the elderly and hence lead to major bone and joint surgery. Elderly patients may suffer from significant cardiorespiratory, renal, and neurologic dysfunction, and they may be malnourished; therefore, preoperative assessment is essential. Both general and regional anaesthesia techniques are commonly used, but regional anaesthesia, with or without sedation, is preferred. The use of cement during surgery is known to be associated with intraoperative morbidities, as is the use of a tourniquet. Antibiotics are routinely used, but they must be administered before th
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43

Youngner, Stuart J., and Robert M. Arnold, eds. The Oxford Handbook of Ethics at the End of Life. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199974412.001.0001.

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This handbook explores the topic of death and dying from the late twentieth to the early twenty-first centuries, with particular emphasis on the United States. In this period, technology has radically changed medical practices and the way we die as structures of power have been reshaped by the rights claims of African Americans, women, gays, students, and, most relevant here, patients. Respecting patients’ values has been recognized as the essential moral component of clinical decision making. Technology’s promise has been seen to have a dark side: it prolongs the dying process. For the first
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44

Muders, Thomas, and Christian Putensen. Pressure-controlled mechanical ventilation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0096.

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Beside reduction in tidal volume limiting peak airway pressure minimizes the risk for ventilator-associated-lung-injury in patients with acute respiratory distress syndrome. Pressure-controlled, time-cycled ventilation (PCV) enables the physician to keep airway pressures under strict limits by presetting inspiratory and expiratory pressures, and cycle times. PCV results in a square-waved airway pressure and a decelerating inspiratory gas flow holding the alveoli inflated for the preset time. Preset pressures and cycle times, and respiratory system mechanics affect alveolar and intrinsic positi
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45

Henning, Jessen. Part I Assessing the UN Institutional Structure for Global Ocean Governance: The UN’s Role in Global Ocean Governance, 3 Advancing the Deep Seabed ‘Mining Code’: Key Environmental Elements of the Regulatory Framework for the Commercial Exploitation of Mineral Resources. Oxford University Press, 2018. http://dx.doi.org/10.1093/law/9780198824152.003.0003.

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This chapter examines the key environmental elements of the International Seabed Authority's (ISA) ‘Mining Code’, a regulatory framework for the commercial exploitation of mineral resources. The term ‘Mining Code’ refers to the whole comprehensive set of rules, regulations and procedures issued by the ISA to regulate prospecting, exploration and exploitation of minerals. The set of rules includes the collaboration of the respective responsibilities of deep seabed explorers and of the ISA in order to ensure environmentally sustainable development of deep seabed mineral resources. The chapter fi
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46

Turkheimer, Eric. The hard question in psychiatric nosology. Edited by Kenneth S. Kendler and Josef Parnas. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198796022.003.0005.

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Nosology is primarily an exercise in grouping like with like: an empirical, quantitative, and theoretical exercise referred to as taxonomy or cladistics. Consideration of the formal process of making decisions about taxonomy reveals some of the choices that must be made in adopting any particular conceptual system for a complex domain such as psychiatric symptomatology. The psychometrician Louis Guttman and the psychopathologist Paul Meehl made key contributions to our understanding of how multivariate phenomena can be codified. Their contributions clarified the role played by empirical data i
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47

Reed, Christopher Robert. Demography and Ethos. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252036231.003.0002.

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The political economy of the 1920s were intricately linked to the demographic changes, emerging social structure, level of racial consciousness, cultural and aesthetic expressions, and religious practices and activities of this pivotal period in Chicago's history. This chapter focuses on demographics and the thinking accompanying the expansion of this population. Between 1910 and 1920, the African American population of Chicago increased by 148.5 percent. By 1927, a head count around the city in all three of the major geographical divisions found 196,569 persons of African descent in residence
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48

Fung, Victor. A Way of Music Education. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190234461.001.0001.

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A Way of Music Education: Classic Chinese Wisdoms presents a philosophy of music education rooted in Yijing (I-Ching or The Book of Changes), classic Confucianism, and classic Daoism, which matured in the mid-sixth to mid-third century BC China (pre-Qin period). This philosophy puts the human at the center of an organismic world, in which all matters and events are connected, be they musical or non-musical. It is human-centric and dao-centric. Music educational experiences are key attributes to musical well-being throughout one’s lifetime. Concepts of yin and yang, deep harmony, and the teachi
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49

Farrell, David M., and Niamh Hardiman, eds. The Oxford Handbook of Irish Politics. Oxford University Press, 2021. http://dx.doi.org/10.1093/oxfordhb/9780198823834.001.0001.

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Ireland has enjoyed continuous democratic government for almost a century, an unusual experience among countries that gained their independence in the twentieth century. But the way this works has changed dramatically over time. Ireland’s colonial past has had an enduring influence over political life, enabling stable institutions of democratic accountability, while also shaping economic underdevelopment and persistent emigration. More recently, membership of the EU has brought about far-reaching transformation across almost all aspects of life. But the paradoxes have only intensified. Now one
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50

MacMaster, Thomas J., and Angela Zhang, eds. A Cultural History of Slavery and Human Trafficking in The Pre-Modern Era. Bloomsbury Publishing Plc, 2024. http://dx.doi.org/10.5040/9781350053762.

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Slavery was a continuous presence throughout the Pre-Modern Era, roughly 500 CE to 1450 CE, an epoch where changes in geopolitical forces, demography, and cultural background all contributed to who could or could not be enslaved. At the same time, coercion as a way of life differed across socio-cultural and economic realities, ranging what are commonly termed chattel slaves and war captives, to sexual and domestic slaves. This volume destabilizes the deep-seated idea that during the so-called “Middle Age” between antiquity and modernity social and cultural relationships remained stagnant. Draw
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