Academic literature on the topic 'Continuous flow'

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Journal articles on the topic "Continuous flow"

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Ötvös, Sándor B. "Continuous-Flow Catalysis." Catalysts 11, no. 9 (August 31, 2021): 1066. http://dx.doi.org/10.3390/catal11091066.

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Britton, Joshua, Sudipta Majumdar, and Gregory A. Weiss. "Continuous flow biocatalysis." Chemical Society Reviews 47, no. 15 (2018): 5891–918. http://dx.doi.org/10.1039/c7cs00906b.

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Golan, Abraham. "Continuous-flow vaginoscopy." Reviews in Gynaecological Practice 3, no. 4 (December 2003): 177–79. http://dx.doi.org/10.1016/s1471-7697(03)00062-5.

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MacLaurin, Paul. "Continuous flow techniques." TrAC Trends in Analytical Chemistry 11, no. 9 (October 1992): IX—X. http://dx.doi.org/10.1016/0165-9936(92)80067-g.

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Teissié, J. "Continuous Flow Electroporation." Nature Biotechnology 6, no. 5 (May 1988): 598. http://dx.doi.org/10.1038/nbt0588-598d.

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Yoshida, Jun-ichi, Aiichiro Nagaki, and Daisuke Yamada. "Continuous flow synthesis." Drug Discovery Today: Technologies 10, no. 1 (March 2013): e53-e59. http://dx.doi.org/10.1016/j.ddtec.2012.10.013.

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Gilmore, Kerry, and Peter H. Seeberger. "Continuous Flow Photochemistry." Chemical Record 14, no. 3 (May 30, 2014): 410–18. http://dx.doi.org/10.1002/tcr.201402035.

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Wang, Huiyue, Zhao Jin, Xin Hu, Qiao Jin, Songwei Tan, Ali Reza Mahdavian, Ning Zhu, and Kai Guo. "Continuous flow cationic polymerizations." Chemical Engineering Journal 430 (February 2022): 132791. http://dx.doi.org/10.1016/j.cej.2021.132791.

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Bhaya, Vinay, Ramesh Joshi, and Amol Kulkarni. "Continuous-Flow Meerwein Arylation." Journal of Flow Chemistry 4, no. 4 (December 10, 2014): 211–16. http://dx.doi.org/10.1556/jfc-d-14-00023.

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Konstam, Marvin A., Barbara Czerska, Michael Böhm, Ron M. Oren, Jerzy Sadowski, Sanjaya Khanal, William T. Abraham, et al. "Continuous Aortic Flow Augmentation." Circulation 112, no. 20 (November 15, 2005): 3107–14. http://dx.doi.org/10.1161/circulationaha.105.555367.

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Dissertations / Theses on the topic "Continuous flow"

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Faizullah, Azad Tawfiq. "Continuous flow injection analysis." Thesis, University of Hull, 1985. http://hydra.hull.ac.uk/resources/hull:16437.

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Pal, S. "Understanding flow of solid in continuous flow reactors." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2019. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/5989.

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McPake, Christopher C. "New continuous flow oxidation methodology." Thesis, Durham University, 2011. http://etheses.dur.ac.uk/3244/.

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The HOF.MeCN complex, formed from the reaction of elementary fluorine with aqueous acetonitrile, was discovered by Shlomo Rozen in 1987 and, in a series of publications, he demonstrated that the complex is a uniquely effective electrophilic oxygen transfer agent. However, it is estimated that the HOF.MeCN complex has a half life of a few hours at 0ºC and thus, must be produced and used immediately when required. In addition to this, highly exothermic, rapid oxidation processes can be problematic with reaction control and safety when reagents are added into an excess of a highly oxidizing medium. Consequently, scale-up of oxidations to a larger industrial level using the HOF.MeCN complex in batch processes would not be possible. In recent years, continuous flow reactors using microchannels have been viewed as a viable method for avoiding many of the problems encountered when a laboratory process is scaled-up. The low chemical inventory of such reactors means that even highly reactive reactions can be performed safely and, with the application of multiple reaction channels in parallel, large quantities of product can be easily obtained. In this thesis we present new continuous flow methodology for the in situ generation of HOF.MeCN and, without isolation, immediate substrate oxidation in a two-step process. The continuous process, therefore, provides a genuine method for oxidizing large quantities of material, without the problems associated with batch oxidations. Scale-up oxidations of various amines, alkenes, and anilines are also presented along with a safe and accurate method for calibrating HOF.MeCN amounts.
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Dahnoun, Naim. "Continuous monitoring of blood flow." Thesis, University of Leicester, 1990. http://hdl.handle.net/2381/34319.

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An extensive review of the literature revealed that there are still significant weakness in the available technology for blood flow measurement. This dissertation describes two techniques for blood velocity measurement. The first is an invasive method which uses multimodal optical fibres for light transmission to and from a sensing tip, which attenuates the light depending upon the blood velocity. The design and construction of this flowmeter is presented and bench results shown. The modulated light is transmitted to the detection and processing circuit and provision is made for the transducer to be insensitive to pressure fluctuations and ambient light. The second technique, which is noninvasive, uses a continuous wave Doppler ultrasonic technique; the instrument designed is a portable directional Doppler velocimeter with purpose-built probes intended for monitoring blood flow in femorodistal bypass grafts in ambulatory patients. This portable unit differs from conventional Doppler units in many respect which are described. This unit has been developed in order to understand the behaviour of blood flow in grafts while the patients are persuing everyday tasks. A postoperative study of successful in situ vein grafts from 8 patients has been undertaken to determine the feasibility of the technique. This pilot study shows that posture can have an effect on blood flow in grafts, and also shows that it is possible to monitor blood velocity with Doppler techniques for a long period of time, without intervention of an operator.
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Lovick, Jonathon. "Horizontal, oil-water flows in the dual continuous flow regime." Thesis, University College London (University of London), 2004. http://discovery.ucl.ac.uk/1383486/.

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The research presented in this thesis is concerned with the flow behaviour of two-phase, liquid-liquid, oil-water flow through horizontal pipes. The test liquids used were oil (density 828kg/rn3, viscosity 6x iO 3 Pa s) and water, with experiments carried out in a purpose built test facility with a stainless steel pipe (internal dia. 38mm, length 8m). Visual observation of the flow was possible at low mixture velocities through a lm transparent pipe at the end of the test section. At higher mixture velocities local probes were used for flow pattern identification. These local probes were a conductivity probe for identifying the continuous phase, and a high frequency impedance probe for measuring local phase distribution. A dual sensor impedance probe was also developed for measuring local drop velocity and also the drop chord length distributions. Pressure gradient was also measured using a differential pressure transducer, and in-situ phase fractions were obtained using Quick Closing Valves. Experimental results show that the dual continuous flow regime, where both phases retain their continuity while there is mixing at the interface, dominates at all input oil fractions at low mixture velocities and intermediate oil fractions at high mixture velocities. In general the pressure drop of the two-phase mixture is lower than that of single phase oil. At higher mixture velocities a minimum in pressure gradient appeared at high oil fractions perhaps as a combination of the drag reduction phenomenon and the relative fraction of the oil and water layers in the pipe. At the highest mixture velocity this minimum was at the boundary of fully dispersed oil continuous flow with dual continuous flow. Velocity ratios are shown to increase with increasing oil fraction at low mixture velocities, with this trend reversing at high mixture velocities. These trends in the pressure gradient and velocity ratio can be explained using the phase distribution diagrams, with the interfacial curvature greatly affecting velocity ratio. Local chord length data shows that, in general, drop sizes decrease with increasing distance from the interface and that oil drops tend to be slightly larger than water drops. Mixture velocity did not significantly affect the drop size of either phase in dual continuous flow. A modified version of the two-fluid model was suggested for dual continuous flow that treats the upper and lower layers as dispersions and uses experimental entrainment to calculate their properties. Better predictions were obtained when friction factors that accounted for the drag reduction phenomenon were used to calculate wall shear stresses.
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Bessoth, Fiona Gabriele. "Microstructure for efficient continuous flow mixing." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367869.

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Scovell, Katherine A. "Continuous flow reactions at high pressure." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.537684.

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Mueller, Simon T. R. "Diazo compounds in continuous flow technology." Thesis, Cardiff University, 2015. http://orca.cf.ac.uk/86662/.

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Diazo compounds are highly reactive carbene precursors which can be used to generate molecular complexity rapidly. However, diazo compounds are highly energetic and dangerous compounds and therefore, their use in large-scale applications remains rare. In this work, the use of continuous flow technology for the safe, efficient and scalable use of diazo compounds is described. By using flow chemistry, diazo compounds were safely generated within small diameter devices and directly used in subsequent reactions without a hazardous isolation of the diazo reagents. This thesis describes five new protocols for the use of diazo compounds. In the first project, ethyl diazoacetate (EDA) was generated safely in flow and used in subsequent aldol addition reactions to aldehydes with high yields (right). The preparation of the organometallic ethyl lithiodiazoacetate species in flow was achieved in the second project and used for the addition to ketones (left). Detailed kinetic and thermal studies on aryl diazoacetates were performed in the third project which yielded a new, multistep continuous flow protocol for the use of donor / acceptor carbenes. Rapid reaction optimisation was achieved using in-line infrared spectroscopy. Purification of the diazo species was performed in flow using in-line liquid / liquid extraction methodology. The fourth protocol entails the rapid assembly of complex lactone-cyclopropane structures of biological interest from diazo compounds in a combination of flow and batch technologies (left). In the final project, the stereoselective preparation of indolines using diazo compounds is discussed (right).
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Sharma, Y. "Continuous flow synthesis of organic compounds." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2017. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/4520.

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Kelly, Liam P. (Liam Porter). "Development of a continuous-flow synthesis of neostigmine methylsulfate and studies toward a continuous-flow synthesis of lisinopril." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122853.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 2019
Cataloged from PDF version of thesis.
Includes bibliographical references.
[color illustration] Herein, we describe the development of a continuous flow synthesis of neostigmine methyl sulfate, an acetylcholinesterase inhibitor on the WHO list of essential medicines, and the transfer of the synthesis into a next-generation reconfigurable frame developed by our collaborators. Starting from 3-dimethylaminophenol, the synthesis provides a throughput of approximately 46.8 g/day (or 93,600 doses/day) of crude neostigmine methyl sulfate. The synthesis also showcases a prototype in-line evaporation unit that operates without any added carrier gas. Dr. Christina Dai performed early screening of lithium bases. Dr. Yuqing Cui and Dr. Naomi Briggs developed the downstream purification sequence. Dr. Nopphon Weeranoppanant developed the in-line evaporator and, along with Dr. Dale Thomas, assisted with performing the synthesis within their developed frame. Liam P. Kelly developed the continuous synthesis of neostigmine methyl sulfate. [color illustration] Lisinopril is a member of a large family of ACE inhibitors generally known as N-carboxyethyl dipeptides. Of this family, lisinopril is the most commonly prescribed. All known routes to lisinopril require isolation of several synthetic intermediates and protecting group manipulations, thus, development of an efficient continuous synthesis would provide great benefit. Herein we describe our investigation of several routes to generate intermediates of lisinopril with the end goal of a fully continuous synthesis, high material throughput, and minimal protecting group manipulations. Liam P. Kelly performed all work described within this chapter.
by Liam P. Kelly.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Chemistry
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Books on the topic "Continuous flow"

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Tundo, Pietro. Continuous flow methods in organic synthesis. New York: Ellis Horwood, 1991.

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Jung, André. Computational modelling of continuous flow sterilisation. Birmingham: University of Birmingham, 1999.

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Glasnov, Toma. Continuous-Flow Chemistry in the Research Laboratory. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32196-7.

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M, Caprioli R., ed. Continuous-flow fast atom bombardment mass spectrometry. Chichester: Wiley, 1990.

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Griffith, Owen Mitch. Techniques of preparative, zonal and continuous flow ultracentrifugation. 5th ed. Palo Alto (Calif.): Beckman Instruments, 1986.

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Saville, D. A. Mathematical models of continuous flow electrophoresis: Final report. [Princeton, N.J.]: Princeton University, 1986.

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George, Harry, and Iron and Steel Society, eds. The Shrouding of steel flow for casting and teeming. Warrendale, PA: Iron and Steel Society, 1986.

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Iowa. Office of Transportation Inventory. and United States. Federal Highway Administration., eds. Iowa permanent continuous automatic traffic recorders, 1981-1990. [Ames, Iowa]: Iowa Dept. of Transportation, 1991.

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Saville, D. A. The fluid mechanics of continuous flow electrophoresis: Final report. Princeton, NJ: Dept. of Chemical Engineering, University of Princeton, 1990.

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Rosa, M. D. Di. CW laser strategies for simultaneous multi-parameter measurements in high-speed gas flows. Washington: AIAA, 1992.

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Book chapters on the topic "Continuous flow"

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Gierusz, Leszek A., and Teresa J. T. Pinheiro. "Continuous Flow." In Encyclopedia of Biophysics, 366–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-16712-6_60.

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Anderson, Larry, Dan Fleming, Bruce Hamilton, and Pat Wardwell. "Improve Flow & Pull." In Continuous Improvement, 85–106. New York: Productivity Press, 2021. http://dx.doi.org/10.4324/9781003216698-8.

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Brandolese, R., and G. Gritti. "Continuous Flow Systems." In Anaesthesia, Pain, Intensive Care and Emergency Medicine - A.P.I.C.E., 117–22. Milano: Springer Milan, 1998. http://dx.doi.org/10.1007/978-88-470-2278-2_11.

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Pieber, Bartholomäus, and C. Oliver Kappe. "Aerobic Oxidations in Continuous Flow." In Organometallic Flow Chemistry, 97–136. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/3418_2015_133.

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Frank, R., H. Leban, M. Kraft, and H. Gausepohl. "Continuous flow peptide synthesis." In Peptides, 215–16. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_63.

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Olsder, Geert Jan. "Synchronized Continuous Flow Systems." In Discrete Event Systems: Modeling and Control, 113–24. Basel: Birkhäuser Basel, 1993. http://dx.doi.org/10.1007/978-3-0348-9120-2_9.

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Fukuyama, Takahide, Akihiro Furuta, and Ilhyong Ryu. "Continuous Flow Synthesis Using Recyclable Reaction Media." In Sustainable Flow Chemistry, 25–42. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527689118.ch2.

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Asselt, W. A., J. J. Geerdink, G. Simbruner, and A. Okken. "Estimated Peripheral Blood Flow in Premature Newborn Infants." In Continuous Transcutaneous Monitoring, 249–51. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1927-6_45.

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Uemura, Tomomasa, Manabu Iguchi, and Yoshiaki Ueda. "Continuous Casting of Molten Steel." In Flow Visualization in Materials Processing, 117–35. Tokyo: Springer Japan, 2017. http://dx.doi.org/10.1007/978-4-431-56567-3_6.

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Caligara, F., G. Rooth, and U. Ewald. "Skin Blood Flow Calculations from Transcutaneous Gas Pressure Measurements." In Continuous Transcutaneous Monitoring, 253–57. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1927-6_46.

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Conference papers on the topic "Continuous flow"

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Bowers, Jr., George H. "Continuous flow manufacturing." In 10th Annual Symposium on Microlithography, edited by James N. Wiley. SPIE, 1991. http://dx.doi.org/10.1117/12.29746.

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Tang, Zineng, Shiyue Zhang, Hyounghun Kim, and Mohit Bansal. "Continuous Language Generative Flow." In Proceedings of the 59th Annual Meeting of the Association for Computational Linguistics and the 11th International Joint Conference on Natural Language Processing (Volume 1: Long Papers). Stroudsburg, PA, USA: Association for Computational Linguistics, 2021. http://dx.doi.org/10.18653/v1/2021.acl-long.355.

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Sandras, William A. "Continuous Flow Customized Production." In SAE International Congress and Exposition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 1985. http://dx.doi.org/10.4271/850587.

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Campos, L. D. O., P. Gardin, S. Vincent, and J. P. Caltagirone. "Physical modeling of turbulent multiphase flow in a continuous casting steel mold." In MULTIPHASE FLOW 2015. Southampton, UK: WIT Press, 2015. http://dx.doi.org/10.2495/mpf150371.

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GORBUNKOV, V. I., V. V. SHALAY, and N. V. PUSTOVOI. "SUPERSONIC ARGON FLOW PARAMETERS IN AN ARCJET THRUSTER." In International Colloquia on Pulsed and Continuous Detonations. TORUS PRESS, 2021. http://dx.doi.org/10.30826/icpcd12b17.

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The small closed volume occupied by cold gas plasma is a feature of the orbit-correction propulsion systems of spacecraft (PSSC). When determining the kinetic parameters of the working fluid flow in the arcjet and argon is selected as the process gas, the most important characteristic is the gas temperature. The well-known statement about the adiabatic nature of the compression process due to an increase in temperature suggests that the compression process is a source of natural gas oscillations and is of paramount importance for establishing the Boltzmann distribution of excited atoms over energy levels. In the Boltzmann approximation, using the methods of emission spectroscopy, the temperature of the working gas in the PSSC was obtained which made it possible to determine the effective flow rate of argon and the corresponding speed of sound. The values of the kinetic parameters of the supersonic argon flow in the arcjet made it possible to substantiate the results of recording the frequency of oscillations of the arc voltage of the PSSC discharge chamber in the Helmholtz resonator mode near fH= 6.25 kHz. It is shown that the length of the discharge chamber in the approximation of a partially open resonator can be of decisive importance in finding the natural vibrations of the resonator. It is suggested that on the basis of the engine under consideration, it is possible to consider the initiation of detonation in a supersonic flow of a combustible mixture.
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Podio, A. L., J. N. McCoy, and M. D. Woods. "Decentralized, Continuous-Flow Gas Anchor." In SPE Production Operations Symposium. Society of Petroleum Engineers, 1995. http://dx.doi.org/10.2118/29537-ms.

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Hartfield, Roy, and Timothy W. Ledlow. "Continuous Flow Rotary Vane Engine." In SAE 2014 World Congress & Exhibition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2014. http://dx.doi.org/10.4271/2014-01-1189.

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Zhao, Zongyi, Xingang Shi, Arpit Gupta, Qing Li, Zhiliang Wang, Bin Xiong, and Xia Yin. "Continuous Flow Measurement with SuperFlow." In 2021 IEEE/ACM 29th International Symposium on Quality of Service (IWQOS). IEEE, 2021. http://dx.doi.org/10.1109/iwqos52092.2021.9521284.

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Baxendale, Ian R. "Continuous Chemical Synthesis in Flow." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-speech12.

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GORBUNKOV, V. I., V. V. SHALAY, and N. V. PUSTOVOI. "THE SUPERSONIC ARGON FLOW PARAMETERS IN AN ARCJET THRUSTER." In 12TH INTERNATIONAL COLLOQUIUM ON PULSED AND CONTINUOUS DETONATIONS. TORUS PRESS, 2020. http://dx.doi.org/10.30826/icpcd12a29.

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A small closed volume occupied by the gas plasma is a specific feature of the propulsion systems for orbit correction of spacecraft (PSSC). We found the temperature of argon in the PSSC chamber using emission spectroscopy methods in the approximation of partial local thermal equilibrium.
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Reports on the topic "Continuous flow"

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Barrett, Louise M., Andrew J. Skulan, Anup K. Singh, Eric B. Cummings, and Gregory J. Fiechtner. Continuous-Flow Detector for Rapid Pathogen Identification. Office of Scientific and Technical Information (OSTI), September 2006. http://dx.doi.org/10.2172/1323909.

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Author, Not Given. Continuous Flow Solid-Catalytic Biodiesel Production Process. Office of Scientific and Technical Information (OSTI), March 2007. http://dx.doi.org/10.2172/942155.

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Robinson, S. M. Development of a continuous-flow fluidic pump. Office of Scientific and Technical Information (OSTI), August 1985. http://dx.doi.org/10.2172/5354448.

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Evans, Amanda Christine, and Gregory Weiss. Continuous Flow Biocatalytic Generation of Green Propellant Fuels. Office of Scientific and Technical Information (OSTI), May 2019. http://dx.doi.org/10.2172/1514922.

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Evans, Amanda Christine. Continuous Flow Biocatalytic Generation of Green Propellant Fuels. Office of Scientific and Technical Information (OSTI), May 2019. http://dx.doi.org/10.2172/1523225.

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Aloisi, Marc, Emily Luteran, Jordan Harper, and Paul Peterson. Cost-efficient temperature mediation of DPMS synthesis in flow using continuous flow chemistry. Office of Scientific and Technical Information (OSTI), June 2024. http://dx.doi.org/10.2172/2377683.

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Dyrkacz, G. R., and C. A. A. Bloomquist. Improved maceral separation method using a continuous flow centrifuge. Office of Scientific and Technical Information (OSTI), March 1994. http://dx.doi.org/10.2172/10132744.

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Aloisi, Marc, Emily Luteran, Wendi Akerley, and Robert Gilbertson. Immobilization of Urease for continuous flow conversion of waste urea. Office of Scientific and Technical Information (OSTI), September 2024. http://dx.doi.org/10.2172/2440690.

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Mills, Chris, and Zak Latif. PR-363-21601-Z01 Flow Sensors for Continuous Equipment Monitoring. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), September 2022. https://doi.org/10.55274/r0012243.

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As a Strategic Research Priority (SRP), one of the key research objectives for PRCI and its members includes reducing Greenhouse Gas (GHG) from pipeline systems by developing, demonstrating, and validating processes and sensors to detect, quantify, and mitigate such releases. Identification of unexpected deviations in unit efficiency would allow operators to make timely repairs or adjustments to restore efficiency and minimize related greenhouse gases required to drive compressors and pumps. This report covers existing and emerging sensors that can be used to install retrofit flow measurement equipment to compressors and pumps, considering the unique equipment challenges.
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Mottola, H. A. [Unsegmented continuous-flow sample processing and electrochemical detection of gaseous species]. Office of Scientific and Technical Information (OSTI), January 1991. http://dx.doi.org/10.2172/6894107.

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