Dissertations / Theses on the topic 'Continuous wavelet analysis'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 21 dissertations / theses for your research on the topic 'Continuous wavelet analysis.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Bunluechokchai, Sonthaya. "Wavelet analysis of the high resolution electrocardiogram for the detection of ventricular late potentials." Thesis, University of Sussex, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288618.
Full textTse, Chung Fai Norman. "The development of complex continuous wavelet transform based harmonic analysis and dynamic waveform reconstruction algorithms." Thesis, City University London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446448.
Full textJaskowak, Daniel Joseph. "Detecting Transient Changes in Gait Using Fractal Scaling of Gait Variability in Conjunction with Gaussian Continuous Wavelet Transform." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/87393.
Full textMaster of Science
Fitness trackers have become widely accessible and easy to use. So much so that athletic teams have been using them to track activity throughout the season. Researchers are able to manipulate data generated from the fitness monitors to assess many different variables including gait. Monitoring gait may generate important information about the condition of the individual. As a person fatigues, running form is theorized to breakdown, which increases injury risk. Therefore the ability to monitor gait may be advantageous in preventing injury. The purpose of this study is to show that the methods in this study are reproducible, respond reasonably to changes in speed, and to observe the changes of gait in the presence of fatigue or on tired legs. Three analyses are used in this study. The first method called autocorrelation, overlays acceleration signals of consecutive foot strikes, and determines the similarity between them. The second method utilizes a wave transformation technique that is able to determine foot contact times. The final method attempts to determine any pattern in the running stride. This method looks for changes in the structure of the pattern. Less structure would indicate a stride that is fatigued. The results showed that the methods of gait analysis used in this study were reproducible and responded appropriately with changes in speed. Small changes in gait were observed due to the presence of fatigue. Further investigation into the use of these methods to determine changes in gait due to the presence of fatigue are warranted.
Maraun, Douglas. "What can we learn from climate data? : Methods for fluctuation, time/scale and phase analysis." Phd thesis, [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=981698980.
Full textHelienek, Matúš. "Simulační a experimentální analýza řezání kotoučovou pilou." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-412924.
Full textZamrane, Zineb. "Recherche d’indices de variabilité climatique dans des séries hydroclmatiques au Maroc : identification, positionnement temporel, tendances et liens avec les fluctuations climatiques : cas des grands bassins de la Moulouya, du Sebou et du Tensift." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT181/document.
Full textThis work is to characterize the temporal and spatial variability of hydroclimatic time series (rainfall, flow) at three large basins in Morocco; (basins of the Sebou and Moulouya Tensift) and look links between the hydrologic variability and climate fluctuation materialized by various climate indices, NAO, SOI, WMOI. The approach to study is based on statistical analysis of time series, related to time and space dimensions.The great watershed of continental scale as Tensift, Sebou and Moulouya in Mediterranean climate under oceanic influence, integrate over large areas the hydrological response to climate and environmental changes (climate fluctuations, precipitation, flows) not only to large spatial and temporal scales, but also to changes in the physical environment anthropogenic (land use changes, developments ...), which sometimes makes difficult to identify the links between hydrological variability and climate variability. The main objective of this work is to determine and quantify the relationships between hydrological variability and climate fluctuations (regionalised precipitation, climate change indexes) across each studied basin and its main sub-basins, via using spectral analysis methods adapted to the study of non-stationary processes (continuous wavelet analysis, coherence analysis wavelet). Many modes of variability are identified from the station analysis (rainfall and flow rates), the annual cycle to 16-22 years, this analysis will be complemented by a grid analysis, the data come from a (SIEREM) file covering the period from 1940 to 1999, which will allow a better understanding of the spatial variability of signals set highlighted. Which is identified frequencies the 1 year 8-16 years, distinguished different time periods at each basin, three main discontinuities identified in 1970, 1980 and 2000. The contribution of climatic indices is important enough it is between 55% and 80%
Bassani, Thiago. "Design of a BCI system using EEG signal analysis with continuous wavelet transformation and Naïves bayes classifier / Thiago Bassani ; orientador, Julio Cesar Nievola." reponame:Biblioteca Digital de Teses e Dissertações da PUC_PR, 2009. http://www.biblioteca.pucpr.br/tede/tde_busca/arquivo.php?codArquivo=1482.
Full textBibliografia: f. 47-52
Uma das questões mais importantes na interface de computador-cérebro é a análise de padrões cerebrais, geralmente representados por sinais elétricos. Este trabalho tem como objetivo introduzir uma ferramenta de mineração de dados para sinais de EEG, anali
One of the most important issues in brain-computer interface (BCI) is the analysis of patterns in brain states generally represented by electrical signals. The main objective of this work is to present an exploratory approach on electroencephalographic (E
Pereira, André Luis Vinagre. "Manutenção preditiva de um par engrenado através da análise de lubrificantes e da análise de vibrações utilizando a transformada de wavelet." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/153304.
Full textApproved for entry into archive by Cristina Alexandra de Godoy null (cristina@adm.feis.unesp.br) on 2018-04-02T12:53:22Z (GMT) No. of bitstreams: 1 pereira_alv_me_ilha.pdf: 7001331 bytes, checksum: 858704904256f11c8131d5f17bd44a78 (MD5)
Made available in DSpace on 2018-04-02T12:53:22Z (GMT). No. of bitstreams: 1 pereira_alv_me_ilha.pdf: 7001331 bytes, checksum: 858704904256f11c8131d5f17bd44a78 (MD5) Previous issue date: 2018-02-27
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Na manutenção preditiva, as análises dos sinais de vibração e das partículas do óleo são frequentemente utilizadas para o diagnóstico de falhas em redutores, porque elas contêm informações das condições de seus elementos mecânicos. Os sinais de vibração de um redutor geralmente têm muito ruído e a relação sinal-ruído é tão baixa que a extração de informações dos componentes do sinal é muito difícil, especialmente em situações práticas. Uma das soluções para este problema é a aplicação de técnicas de processamento do sinal para facilitar a obtenção de informações. Neste trabalho, uma técnica de cancelamento de ruído, a média temporal síncrona (TSA), e outra técnica da transformada contínua de wavelet de Morlet foram desenvolvidas para extração de recursos e diagnóstico de diferentes tipos de danos locais da engrenagem. Estas técnicas são aplicadas em sinais medidos em uma bancada experimental, que consiste em um par engrenado acoplado a um motor e a um gerador. Outro método para monitorar o estado do sistema é pela análise de partículas presente no óleo provenientes do desgaste das engrenagens. Avaliando a quantidade, formato, tamanho e material das partículas é possível obter informações das condições do equipamento e do tipo de desgaste ocorrido. Neste trabalho, foram feitas a análise do óleo pelas técnicas da ferrografia e contagem de partículas. A parte experimental deste trabalho foi dividida em dois experimentos. No primeiro experimento as condições de um par engrenado durante toda a sua vida útil foi monitorada, enquanto que no segundo experimento, um entalhe foi feito na raiz do dente simulando uma trinca por fadiga. A análise das partículas de óleo mostrou quais tipos de desgastes estava ocorrendo e a técnica da transformada contínua de wavelet mostrou-se precisa na identificação de falhas em dentes de engrenagens, sendo possível indicar em qual dente a falha estava se desenvolvendo.
At the predictive maintenance, the vibration signals analysis and oil particles analysis are frequently used to diagnose failures in a gearbox, because they contain information about the condition of its mechanic’s elements. The vibration signals of a gearbox usually have a lot of noise and the ratio ‘signal-noise’ is very low, making the extraction of information from the signals component very hard, especially in a practical situation. One of the solutions to this problem is the application of technics of signal processing, to improve the collection of information. At this study, a technique of noise cancellation, Temporal Synchronous Average (TSA) and another technique called continuous transform with the Morlet wavelet were executed for the extraction of resources and diagnostics of different type of gears local damages. Those methods are applied to signals measured on an experimental test stand, consisting of a gearbox with an engine and a generator. Another method for monitoring system wear is by analyzing wear particles in the oil generated due to the wear on the gears. By evaluating the quantity, shape, size and material of the particles it is possible to obtain information about the conditions of the equipment and the type of wear that has occurred. During this work, it was done the analysis of the oil by the techniques of ferrography and particle counting. The experimental part of this study was divided into two experiments. On the first experiment was monitored the conditions of a couple meshed throughout its useful life and in the second was made a notch in the root of the tooth simulating a crack by fatigue. The analysis of the oil particles showed what types of wear was occurring and the technique of the continuous wavelet transform was accurate in the identification of defects in gear's teeth, and it was possible to indicate which tooth was failing.
Nes, Preben Gråberg. "Edge-Detection in Signals using the Continuous Wavelet-Transform. : Edge-Detection in Medical UltraSound Images." Thesis, Norwegian University of Science and Technology, Department of Mathematical Sciences, 2006. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-9498.
Full textToday, UltraSound (US) images are often used in medical examination and surgery. An improvement of the quality of these US-images will lead to many advantages, which is a big motivation for research on this field. One obstacle in improving the quality of the images is the presence of noise and texture. In order to distinguish this unwanted information from the interesting objects, different techniques can be used. Characteristic features, such as the ability to find vague contours, small objects or edges of small strength, decides if the technique is suitable for analysing noisy signals. This thesis presents different techniques for finding objects in US-images by using the continuous wavelet-transform. One observation from the analysis is that for edge-detectors using the wavelet-transform at a single scale, there is a compromise between accuracy and reliability. One has to choose between detecting small objects or vague contours. At fine scales one is able to detect small objects, but not objects with a vague contour without including redundant information. At coarse scales one is able to detect vague contours without including redundant information, but one will not detect small objects. The Lipschitz-regularity and the length of a maxima-line in the time-scale plane works well to find the points where the signal changes with a long duration, but is less suitable to find small objects and to remove unwanted information. By using the value of the wavelet-transform at several scales, it is possible to find vague contours in images, small objects, and edges of small strength compared to the strength of the noise. Another important observation from the analysis is that use of the circumference of objects is appropriate in order to find the most important objects in an image. Using this information has been very useful with respect to the analysis of US-images. Medical ultra-sound images are in general of varying quality. In addition the quality of a US-image will typically change within the signal, and changes with respect to the quality of the contour of objects and the influence of noise. The technique which in general is most reliable and produces the best representations of the US-images analysed in this thesis, uses information about the amplitude of the wavelet-transform both within and across scales, in addition to information about the circumference of the objects. This combined edge-detector is reliable with respect to represent the important objects in the image, and this representation is often easily obtained by the edge-detector.
Vu, Phuong Lan. "Altimétrie spatiale, réflectométrie GNSS et surcotes marines." Thesis, Toulouse 3, 2019. http://www.theses.fr/2019TOU30076.
Full textThe objective of this PhD thesis was to develop an innovative remote sensing methodology, based on existing platforms, to monitor the main factors influencing coastal dynamics. We propose monitoring based on a classic tool i.e. satellite altimetry but with a focus on new space missions (SARAL, Sentinel-3). Whose contributions will be evaluated, particularly in the coastal zone, which is the most critical from a socio-economic point of view? I have focused my attention on the French Atlantic coast between La Rochelle and Bayonne. We will also rely on an original technique based on the reflection of GNSS positioning satellites (technical known as GNSS-R). These tools will allow us to precisely monitor the various tidal waves, but they have also allowed us to detect more unusual phenomena such as the extreme event of 2010: the storm Xynthia that affected the coasts of southern Europe. These tools demonstrate that it is also possible will also be able to see to monitor the coastal dynamics related to swell variations and its impact on coastal erosion, and even the effects of the strong atmospheric depression associated with Xynthia, which has had a measurable impact on the local sea level of the Atlantic Ocean. My thesis is focused on two complementary approaches based on two scales of study: the first one is global and used satellite altimetry, the second one is more local and focused on the extreme event detection and it is based on the GNSS reflectometry. The first study, which I carried out, relies on different satellite altimetry missions (ERS-2, Jason- 1/2/3, ENVISAT, SARAL) which allowed us to follow the sea level variations (SSH) from the French Atlantic coast to the south of the Bay of Biscay during the 1995-2015 period. SARAL data, including a footprint of around 6 km, show that it is now possible to approach the coastal fringe up to ~ 10 km with a great precision (RMSE ~ 20 cm). The second application is based on the GNSS-R methodology that we used to track SSH in the inner part of the bay of Saint Jean de Luz - Socoa during the storm Xynthia. Here again the results are exceptional since they allowed us to follow the impact of the storm Xynthia on the local level of the ocean. I thus highlighted that it was possible with only one instrument to follow the effects of the tides, and even the effects of the marine surges which associated to the impact of the atmospheric pressure on the sea level give a good correlation (R = 0.77 between the RC3 component and the surge, and R = 0.73 with the atmospheric pressure) during storm. Finally we also looked at what is happening in the transition between continental and oceanic waters for the deltas of the Red River and Mekong in Vietnam. And, even if the time series are rather short or truncated (Red River) the results are more than encouraging since they allowed us to follow the flooding events associated with two tropical storms (Mirinae and Nida) and to measure the delay between the rain falls and the propagation of the flood wave which shows in this case a delay of 48 h for Nida. With the deployment of permanent GNSS networks in many countries, this technique can be applied when a permanent GNSS station is located near the shore. The GNSS-R approach can be used to monitor sea level variations but also the effect of extreme events. For that we used 3 months of recordings (January-March 2010) from the Socoa GNSS station to determine the tidal components in the GNSS-R signals and to identify the Xynthia storm
Doležal, Petr. "Časově-frekvenční analýza elektrogramů." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2015. http://www.nusl.cz/ntk/nusl-221321.
Full textSamad, Sarah. "Contactless detection of cardiopulmonary activity for a person in different scenarios." Thesis, Rennes, INSA, 2017. http://www.theses.fr/2017ISAR0030/document.
Full textNowadays, contact-less monitoring patient's heartbeat using Doppler radar has attracted considerable interest of researchers, especially when the traditional electrocardiogram (ECG) measurements with fixed electrodes is not practical in some cases like infants at risk or sudden infant syndrome or burn victims. Due to the microwave sensitivity toward tiny movements, radar has been employed as a noninvasive monitoring system of human cardiopulmonary activity. According to Doppler effect, a constant frequency signal reflected off an object having a varying displacement will result in a reflected signal, but with a time varying phase. In our case, the object is the patient's chest; the reflected signal of the person's chest contains information about the heartbeat and respiration. The system is based on a vector network analyzer and 2 horn antennas. The S21 is computed using a vector network analyzer. The phase variation of S21 contains information about cardiopulmonary activity. Processing techniques are used to extract the heartbeat signal from the S21 phase. This thesis presents a comparative study in heartbeat detection, considering different radiated powers and frequencies. The radiated powers used are between 3 and -17 dBm and the operational frequencies used are 2.4, 5.8, 10 and 20 GHz. This helps to make a compromise between the minimum power emitted and the complexity of the measurement system. In addition, a comparative study of several signal processing methods is proposed to extract the best technique for heartbeat measurement and thus to extract its parameters. Processing techniques are based on wavelet transforms and conventional filtering in order to make a comparison between them. The parameter extracted in this thesis is the heartbeat rate HR. Measurements were performed simultaneously with a PC-based electrocardiograph to validate the heartbeat rate measurement. Since the person can move from a room to another inside his home, measurements from the four sides of the person and behind a wall are performed. In addition, a modeling approach based on cardio-respiratory measurement for a person who is walking forward is presented. Furthermore, a comparison between single and two-antenna microwave systems for a non-breathing person is carried out to test the accuracy of the single-antenna system relative to the two antenna microwave system. After that, measurements are performed using one antenna microwave system for a person who breathes normally
Khan, W., Ping Jiang, and David R. W. Holton. "Word spotting in continuous speech using wavelet transform." 2014. http://hdl.handle.net/10454/10713.
Full textWord spotting in continuous speech is considered a challenging issue due to dynamic nature of speech. Literature contains a variety of novel techniques for the isolated word recognition and spotting. Most of these techniques are based on pattern recognition and similarity measures. This paper amalgamates the use of different techniques that includes wavelet transform, feature extraction and Euclidean distance. Based on the acoustic features, the proposed system is capable of identifying and localizing a target (test) word in a continuous speech of any length. Wavelet transform is used for the time-frequency representation and filtration of speech signal. Only high intensity frequency components are passed to feature extraction and matching process resulting robust performance in terms of matching as well as computational cost.
Yen-YuShen and 沈彥佑. "Analysis of Non-contact Vital Sign Signals Using Continuous Wavelet Transform." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/68257401755056579535.
Full text國立成功大學
電機工程學系碩博士班
101
An automatic computer-aided digital signal processor for Doppler radar vital signs healthcare monitoring is described. A voltage waveform signal containing heart-beat and respiration signatures are band-pass filtered for the heart signal. The proposed method, combination of continuous wavelet transform (CWT) and peak finding, is used to adaptively detect heart-beat rate for each of these phase modulated Doppler radar signals. Involving in electrocardiogram, well-developed medical aid, realizes a complete non-contact vital signs monitoring system. An investigation of heart rate variability (HRV) measurements is adopted for the cardiopulmonary disease prognosis. Experimental results show that the proposed algorithm not only provides an accurate heart rate detection but also be able to evaluate heart rate variability (HRV).
Jiang, A. S., and 江安生. "Application of time-frequency and characteristic analysis for EEG energy values before and after acupuncture with continuous wavelet transform." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/31477910444075913067.
Full text建國科技大學
機電光系統研究所
94
The purpose of this research is to study the effect for acupuncture by analysis of EEG using technology of continuous wavelet transform (CWT). According to definition of EEG, the signal was decomposed into a combination of delta(0.5-4Hz), theta(5-8Hz), alpha(8-13Hz), and beta(13-30Hz). There are 24 male normal subjects were enrolled in this study, and their age is between 20 and 24 years old. Electrode points measured are at the position of T3 and T4 in temporal areas. All the measuring time is 30 minutes. Subjects are eyes-closed in 5 minutes before acupuncture. Then, the EEG signal is continuously recorded for 20 minutes. During this time, subjects keep eyes-closed and conscious. The EEG keeps on recording for 5 minutes after acupuncture. A continuous wavelet transform maps a time function into a two-dimensional function of time and frequency. For characteristic and quantitative analysis, we proposed a analytic time-frequency method to obtain energy from each wave band of EEG, and a Wilcoxon signed rank test is employed to see if acupuncture is significant. The results show that: 1. After deep acupuncture, left beta wave decline (12~16%) statistically between 9th and 20th minutes, and so does right beta wave between 10th and 20th minutes (10~14%). 2. After minimal acupuncture, left alpha wave decline (6-13%) statistically between 7th and 14th minutes, and so does right alpha wave (12-18%). Left beta wave decline (17~20%) statistically between 10th and 20th minutes, and so does right beta wave between 9th and 18th minutes (13~21%). 3. There is no significant variation between 21th~25th minutes the time no acupuncture.
Vaidya, Anil Pralhad. "A Model Study For The Application Of Wavelet And Neural Network For Identification And Localization Of Partial Discharges In Transformers." Thesis, 2004. http://etd.iisc.ernet.in/handle/2005/1183.
Full textZhan, Yi-Rong, and 詹依蓉. "Using the Continuous Wavelet Analysis Method to Explore the Dynamic Relationship between Female Wage and Low Fertility Together with Ageing Population." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/27838279896756945757.
Full text南開科技大學
福祉科技與服務管理所
102
ABSTRACT (1)Objectives: The purposes of this study are twofold: first, we explore the dynamic relationship between female wage and fertility, and second, we investigate the dynamic relationship between fertility and ageing population in Taiwan. The results generated from this study not only can provide a complete picture of the dynamic relationship between business cycle and low fertility together with ageing population but also can serve as an important reference for the policymaker to increase the female fertility in Taiwan . (2)Materials and Methods The monthly data used in this study include crude birth rate, marriage rate, number of aged 65 and over and female wage from 1978-2012 in five municipal areas in Taiwan. We performed the continuous wavelet analysis to investigate the eight hypotheses:(H1)female wage positively leading fertility,(H2)female wage negatively leading fertility,(H3)female wage positively lagging fertility,(H4)female wage negatively lagging fertility,(H5)fertility positively leading ageing population,(H6)fertility negatively leading ageing population,(H7)fertility positively lagging ageing population, and(H8)fertility negatively lagging ageing population hypotheses. The first four hypotheses are corresponding to the first purpose of this study, and the rest four hypotheses are corresponding to the second purpose of this study. (3)Results Our results showed that there exists a negative relationship between female wage and fertility, and in the short and long run, fertility is a leading index of the female wage, a result consistent with the female wage negatively lagging fertility hypothesis. In the medium run, however, fertility positively led the female wage, a result predicted by the female wage positively lagging hypothesis. In addition, there exists a negative relationship between fertility and ageing population, and the fertility negatively leading ageing population hypothesis is validated for all periodicities in Taiwan area. (4)Conclusion The results of this study found that the way to increase fertility is the most important policy to reduce the ageing population. In addition, the female wage negatively (positively) lagging fertility hypothesis was observed in the short and long (medium) run. Therefore, an appropriate fertility plan may serves as an important policy instrument to stimulate economics in the short and long run. In the medium run, Taiwan government should encourage fertility that increases labor force benefit the economic development for Taiwan. Keywords : Continuous wavelet analysis, Ageing population, Lowest-low Fertility, Business cycle.
Carvalho, Madalena Moura Trindade Rodrigues de. "Uma análise comparativa dos índices PSI 20, IBEX 35 e DAX 30 usando onduletas." Master's thesis, 2015. http://hdl.handle.net/10316/31737.
Full textO presente trabalho pretende aprofundar o estudo de três índices bolsistas europeus, PSI 20, IBEX 35 e DAX 30, utilizando para tal uma abordagem recente, a análise com onduletas. As características únicas das séries financeiras, como a ausência de estacionaridade, a presença de clusters de volatilidade e do efeito alavanca, exigem uma ferramenta minuciosa capaz de analisar profundamente a série. A análise com onduletas permite realizar a decomposição da série em vários níveis de detalhe e de aproximação, tendo em conta o domínio do tempo e o domínio da frequência simultaneamente. A relação entre os rendimentos dos três índices em estudo é avaliada utilizando uma abordagem baseada em onduletas. Os resultados mostram como estes três índices bolsistas se encontram bem correlacionados para frequências baixas.
The aim of this work is to develop the study of three european stock market indexes, PSI 20, IBEX 35 and DAX 30, using a very promising tool called: wavelet analysis. Time series of financial asset returns often exhibit volatility clustering and leverage effects which require a great tool, capable of decomposing a time series in a set of detail and approximation coeficients into a time-frequency space. The link between the three stock market indexes is analised with a wavelet-based measure. The results show that these european stock markets are highly integrated at lower frequencies.
Lanka, Karthikeyan. "Predictability of Nonstationary Time Series using Wavelet and Empirical Mode Decomposition Based ARMA Models." Thesis, 2013. http://etd.iisc.ernet.in/2005/3363.
Full textBeausoleil, Thierry P. "Techniques de spectroscopie proche infrarouge et analyses dans le plan temps-fréquence appliquées à l’évaluation hémodynamique du très grand prématuré." Thèse, 2017. http://hdl.handle.net/1866/20527.
Full textΤσαρούχας, Νικόλαος. "Electrophysiologιcal study of brain hypoxia." Thesis, 2009. http://nemertes.lis.upatras.gr/jspui/handle/10889/4120.
Full textΗ παρούσα ερευνητική εργασία στοχεύει στην ανάπτυξη εργαλείων Βιοϊατρικής Νευρομηχανικής (Βιοτεχνολογίες) για την σε βάθος λειτουργική μελέτη, ταχεία διάγνωση, συνεχή παρακολούθηση και έγκαιρη αντιμετώπιση οξέων και χρόνιων εγκεφαλικών διαταραχών, ατόμων που υπόκεινται σε ή πάσχουν από οιαδήποτε μορφή συστηματικής υποξαιμίας ή πιο εντοπισμένης εγκεφαλικής υποξίας, καθώς και για την λειτουργική αξιολόγηση και το συνεχή έλεγχο της προσαρμοστικότητας κατά την εξάσκηση των «υψιβατών», και γενικότερα ατόμων που ασκούν δραστηριότητες και λειτουργούν μέσα σε περιβάλλοντα αυξημένων οπτικο-γνωστικο-κινητικών απαιτήσεων (ένα είδος «στρες τεστ» για τον εγκέφαλο). Για το σκοπό αυτό υποβάλλουμε ολόκληρο το οπτικογνωστικό σύστημα, από το στοιχειώδες αισθητηριακό έως το πιο πολύπλοκο νοητικό επίπεδο, σε μια πειραματική δοκιμασία κατηγορικής διάκρισης σύνθετων οπτικογνωστικών ερεθισμάτων, μετά από υπερταχεία οπτική διέγερση που οδηγεί στην έκλυση κινητικής απάντησης κατά την κατηγοριοποίηση στόχων (εικόνες «ζώων» εκλύουν παραγωγικές αποκρίσεις) και στην καταστολή της κατά την κατηγοριοποίηση μη-στόχων (εικόνες «μη-ζώων» εκλύουν ανασταλτικές αποκρίσεις). Οι ταλαντωτικές ηλεκτροφυσιολογικές αποκρίσεις που συγχρόνως καταγράφονται στις ινιακές-κροταφικές-βρεγματικές περιοχές του εγκεφάλου αναλύονται στο πεδίο του χρόνου (<20Hz) και στο συζευγμένο χρονοφασματικό πεδίο ευρυζωνικά (1-60Hz) με το συνεχή μετασχηματισμό του κυματίου που βελτιστοποιεί την πολυφασματική ανάλυση της υψίσυχνης (≥20Hz) γ-ταλαντωτικής δραστηριότητας. Αυτή η δοκιμασία οπτικογνωστικής κατηγοριοποίησης λαμβάνει χώρα τόσο σε νορμοξαιμικές όσο και υποξαιμικές συνθήκες (ελεγχόμενη μείωση στον κορεσμό του αίματος σε οξυγόνο από ≥97% γύρω στο 80% για 15 λεπτά κάτω από συνθήκες υποβαρικής υποξίας μέσα σε υποβαρικό θάλαμο), προκειμένου να ελέγξουμε ηλεκτροφυσιολογικούς δείκτες που μπορούν να ανιχνεύσουν και να συλλάβουν με τον πιο ευαίσθητο και δυναμικό τρόπο ακόμη και τόσο βραχύβιες και σχετικά ήπιες μεταβολές της εγκεφαλικής λειτουργίας. Η στατιστική παραμετρική ανάλυση των χρονοφασματικών χαρτών και η γενικευμένη, στατιστικά πιο ασφαλής, μέθοδος ανάλυσης των διακυμάνσεων ανέδειξαν ως πλέον ευαίσθητους και αξιόπιστους τους ακόλουθους δείκτες: τις κύριες αιχμές των προκλητών δυναμικών, τον παράγοντα φασικής συνάφειας των ταλαντώσεων μεταξύ των μοναδιαίων καταγραφών και την εκλυόμενη ενέργεια των προκλητών/φασικά-κλειδωμένων και επαγόμενων/ολικών ταλαντώσεων. Οι ηλεκτροφυσιολογικοί αυτοί δείκτες σε συνδυασμό με ψυχομετρικές δοκιμασίες επιτρέπουν τη διερεύνηση των σταδίων/επιπέδων κάμψης καθώς και των αποθεμάτων αντιρρόπησης των οπτικο-αντιληπτικών και γνωστικών-νοητικών λειτουργιών του εγκεφάλου για τον καθορισμό των λειτουργικών ουδών ευαισθησίας διάφορων εγκεφαλικών λειτουργιών στην υποξία. Ανοίγουν μάλιστα το δρόμο. για το λειτουργικό χαρακτηρισμό, τη διάγνωση και την παρακολούθηση εγκεφαλικών προσβολών ή άλλων οξέων και χρόνιων παθολογικών καταστάσεων του εγκεφάλου.