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Relevant bibliographies by topics / Contractilité vasculaire / Dissertations / Theses

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Dissertations / Theses on the topic 'Contractilité vasculaire'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Lisowska, Justyna. "Control by CCM complex of the dialog between integrins and cadherins for the vascular stability." Thesis, Grenoble, 2014. http://www.theses.fr/2014GRENV065.

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Les interactions cellule-cellule et cellule-matrice extracellulaire (MEC) sont cruciales pour entretenir la cohésion tissulaire. Ces deux types d'adhésions sont fonctionnellement interconnectés par un dialogue permanent qui met en jeu des voies de signalisation convergentes régulant notamment l'architecture et la contractilité du cytosquelette d'acto-myosine sous-jacent. Ce dialogue permet d'établir un équilibre de forces intracellulaires en réponse à la tension appliquée par le milieu extérieur. L'endothélium des vaisseaux sanguins est un tissu soumis à des conditions mécaniques particulières

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2

El, Dirani Zeinab. "Effet de l’hypoxie intermittente et de l’entraînement physique intensif sur la structure et la fonction du tissu musculaire chez le rat." Thesis, Université Grenoble Alpes (ComUE), 2018. http://www.theses.fr/2018GREAV067/document.

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Le syndrome d'apnée obstructive du sommeil (SAOS), est une maladie chronique qui se caractérise par des interruptions répétées de la respiration durant le sommeil en raison de la fermeture temporaire des voies aériennes supérieures. L'hypoxie intermittente chronique (HI) résultante de cette fermeture transitoire des voies aériennes supérieures, constitue l’une des conséquences majeures du SAOS, et elle est la responsable de la plupart des complications liées à cette pathologie, dont nous citons: l’hypertension artérielle, l’infarctus de myocarde et plus généralement le remodelage cardiovascula

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3

Faury, Gilles. "Action des peptides de l'elastine sur le metabolisme calcique des cellules endotheliales vasculaires et sur la contractilite vasculaire au cours du vieillissement." Université Joseph Fourier (Grenoble), 1996. http://www.theses.fr/1996GRE10111.

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L'elasticite des parois vasculaires est due a la presence d'une proteine fibreuse de la matrice extracellulaire, l'elastine. Au cours du vieillissement ou des pathologies vasculaires, l'elastine est degradee en peptides qui peuvent devenir circulants et qui possedent un recepteur a haute affinite, present sur la membrane des cellules vasculaires. Nous avons montre que les peptides d'elastine, a des concentrations circulantes, provoquent, sur des anneaux aortiques de rats adultes, une vasodilatation dependante de l'endothelium et de la dose, mais n'exercent pas cette activite sur des anneaux de

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4

Topors, Mourad. "Vasoregulatory gene expression and vascular contractility following hypoxia." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37849.

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The overall aim of this thesis was to analyze the expression of key vasoregulatory genes in the vascular endothelium and smooth muscle following hypoxia. Hypoxia caused a reversal in endothelial cell function such that the vascular endothelium enhanced alpha-agonist induced contractions. Downregulation of endothelial nitric oxide synthase (eNOS) and impaired endothelium-dependent vasodilation were observed in the aortas of rats exposed to hypoxia for 12 and 48 hours. Following stimulation of aortic rings with acetylcholine, cyclic GMP and nitrite levels were also reduced. Decreased endothelial

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5

Ji, Junzhi. "Regulatory roles of nitric oxide in vascular smooth muscle contractility." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq22608.pdf.

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6

Tay, Jacqueline I.-Yen. "Human fallopian tubes : in-vitro vascular perfusion and tubal contractility." Thesis, University of Leicester, 2003. http://hdl.handle.net/2381/29445.

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The Fallopian tubes are organs of transport and the tubal fluid nourishes the embryo during this time. Their role, however, has largely been neglected since the development of in vitro fertilisation. Studies of tubal physiology have been limited by the relative inaccessibility of the tubes, problems with collecting neat tubal fluid and difficulties in developing tests which reliably assess tubal function rather than tubal patency. This thesis sets out to validate the technique of in vitro vascular perfusion of the Fallopian tubes and to demonstrate that it is a reproducible technique which can

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7

Abebe, Worku. "Noradrenaline-induced vascular contractility and phosphoinositide metabolism in streptozotocin-diabetic rats." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/30549.

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Alterations in the reactivity of blood vessels to neurotransmitters and circulating hormones have been suggested to cause, or contribute to, some of the cardiovascular complications associated with diabetes mellitus. Previous studies have demonstrated that aortae and mesenteric arteries from male rats with streptozotocin (STZ)-induced diabetes of 12 weeks duration are more responsive to the contractile effects of noradrenaline (NA). The increased responsiveness of the diabetic arteries to NA has been reported to result from stimulation of α₁-adrenoceptors. Contraction of vascular smooth muscle

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8

AL-Kheraije, Khalid. "The role of human profilin in vascular smooth muscle contractility and hypertension /." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486402957195511.

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9

Mukerji, Mark Sanjiv. "The effects of progesterone and related compounds on the contractility of rat vascular smooth muscle." Thesis, Lancaster University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302393.

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10

Constable, Peter David. "The effect of hypertonic saline and hyperosmotic dextrose on cardiac contractility and ventricular-vascular coupling /." The Ohio State University, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487777901660005.

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11

Egert, Amanda M. "EFFECT OF DIETARY EXPOSURE TO ERGOT ALKALOIDS ON CONTRACTILITY OF BOVINE MESENTERIC VASCULATURE AND RUMEN MOTILITY." UKnowledge, 2014. http://uknowledge.uky.edu/animalsci_etds/40.

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Endophyte-infected (E+) tall fescue grass has been associated with fescue toxicosis, a costly syndrome characterized by poor cattle performance and health resulting in significant production losses. The fungal endophyte produces ergot alkaloids, which help the grass thrive in poor conditions but are toxic to mammals. A number of symptoms of fescue toxicosis can be related to vasoconstriction of bovine core, peripheral, and foregut vasculature. The first part of this series of experiments demonstrated ergot alkaloids were also vasoactive in midgut vasculature, with the exception of lysergic aci

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12

Lewis, Sophronia. "The effect of ablation and acute inhibition of plasma membrane calcium ATPase 4 (PMCA4) with a novel inhibitor on isolated mouse mesenteric resistance arterial contractility." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/the-effect-of-ablation-and-acute-inhibition-of-plasma-membrane-calcium-atpase-4-pmca4-with-a-novel-inhibitor-on-isolated-mouse-mesenteric-resistance-arterial-contractility(676a26ea-867e-4947-9544-76b356fce23a).html.

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Plasma membrane calcium ATPase 4 (PMCA4) is a calcium extrusion pump which may also modulate Ca2+-triggered signal transduction pathways. Previous studies postulate that PMCA4 modulates signalling via an interaction with neuronal nitric oxide synthase (nNOS) in localised plasmalemmal microdomains. The effect of PMCA4 on vascular contractility is unclear. This project has utilised PMCA4 ablated mice (PMCA4 KO (-/-)) and a novel specific PMCA4 inhibitor (termed AP2) to study the role of PMCA4 in mouse resistance artery contractility.Immunohistochemistry, Western blotting and polymerase chain rea

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13

Zaborska, Karolina Emilia. "Consequences of maternal obesity on vascular contractility and perivascular adipose tissue regulation of resistance artery tone in rats." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/consequences-of-maternal-obesity-on-vascular-contractility-and-perivascular-adipose-tissue-regulation-of-resistance-artery-tone-in-rats(120fc687-c67a-442c-b87d-92be0fa2b558).html.

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Background: Maternal obesity pre-programme offspring to develop obesity and associated cardiovascular disease later in life. In health, perivascular adipose tissue (PVAT) reduces vascular contractility, an effect lost in obesity and during pregnancy. However, neither the effect of obesity during pregnancy on PVAT function in the mothers nor the possible epigenetic effect in the offspring is known. This study sought to identify detrimental vascular changes in post-partum dams and their offspring resulting from maternal obesity. Methods: Six-eight week old female Sprague-Dawley rats were fed a 1

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14

Simonet, Serge. "Effets de la stimulation adrenergique et serotoninergique sur le muscle lisse de l'artere coronaire de mouton : role de l'endothelium dans la regulation du tonus vasculaire." Poitiers, 1988. http://www.theses.fr/1988POIT2283.

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15

Imsirovic, Jasmin. "Effects of variable mechanical stimuli on vascular smooth muscle contractility." Thesis, 2017. https://hdl.handle.net/2144/20844.

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Cells within the aortic wall are exposed to variable cyclic mechanical stimuli due to variability in blood pressure. Vascular smooth muscle cells, which have been shown to play an important role in maintaining aortic wall tension and stiffness, respond to mechanical stretch by reorganizing their cytoskeletal and contractile elements, which requires energy produced by the mitochondria. Mitochondria have also been implicated as a sensor in mechanotransduction pathways. We have shown recently that cells transduce fluctuations in their mechanical environment by reorganizing their cytoskeletal and

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16

Elavalakanar, Pavania. "Bcl11b regulates arterial stiffness by regulating vascular smooth muscle contractility." Thesis, 2017. https://hdl.handle.net/2144/23716.

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BACKGROUND: Arterial stiffness (AS), or loss of elastic compliance of large arteries, is an independent risk factor for cardiovascular events1. A recent study demonstrated that single nucleotide polymorphisms (SNPs) in a genetic locus downstream of the gene Bcl11b are associated with AS2. However, how this genetic locus and Bcl11b regulate AS is unknown. OBJECTIVES: To determine the molecular mechanisms by which Bcl11b effects the aortic wall and AS. METHODS: Vascular smooth muscle (VSM) cells were isolated from aortas of wildtype (WT) mice and mice with VSM-specific Bcl11b deletion (BKO).

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17

孫千媚. "Effect of Red Wine on Vascular Contractility in Spontaneously Hypertensive Rats." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/22139763344453492292.

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碩士<br>國防醫學院<br>生理學研究所<br>88<br>Abstract Coronary heart disease is the most significant cause of death in the industrialized countries. The potential factors which influenced the development and the courses of the disease have been of great interest during the last decades. Since the early 1970s, there have been increasing evidences that the consumption of moderate amounts of wine is inversely correlated with the mortality of myocardial infarction. A study showing that the mortality due to myocardial infarction was lowered by 50% at moderate consumption of 40 ml of wine each

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18

Rahman, Mohammad Mahmudur. "Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release." Thesis, 2006. http://hdl.handle.net/2429/18128.

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The effect of chronic cigarette smoking on endothelin modulation of vascular contraction and CYP enzyme levels was studied in 20 male Sprague-Dawley rats. The animals were divided equally into smoking and non-smoking groups. The smoking group was exposed to 6 research cigarettes per rat per day 5 days a week for 16 weeks. The control group was sham smoked. Functional contractile studies were performed in aortas and carotid arteries to determine the regulation of vascular tone by basal release of endothelin. Liver samples were analyzed for CYPIAI and CYPIA2 gene expression by RT-PCR. Plasma sam

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19

Omar, Nivin. "A study of the role of actin polymerization in the regulation of vascular contractility in a mouse model." Thesis, 2017. https://hdl.handle.net/2144/23311.

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Cardiovascular disease is the leading cause of death in the United States and globally. Aortic stiffness has recently been implicated as an independent risk factor and has attracted research efforts to prevent cardiovascular diseases. More recently, vascular smooth muscle cell stiffness has been proven to play an important role in aortic stiffness, but the precise mechanism of how smooth muscle contributes to vascular stiffness is still unknown. Studying VSMCs (vascular smooth muscle cells) in depth is a hot topic for ongoing research in this decade because, by understanding the mechanisms inv

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