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Relevant bibliographies by topics / Contractility measurements

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Academic literature on the topic 'Contractility measurements'

Author: Grafiati

Published: 4 September 2021

Last updated: 8 February 2022

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Journal articles on the topic "Contractility measurements"

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Cao, L., E. Manders, and M. Helmes. "Automatic detection of adult cardiomyocyte for high throughput measurements of calcium and contractility." PLOS ONE 16, no. 9 (2021): e0256713. http://dx.doi.org/10.1371/journal.pone.0256713.

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Simultaneous calcium and contractility measurements on isolated adult cardiomyocytes have been the gold standard for the last decades to study cardiac (patho)physiology. However, the throughput of this system is low which limits the number of compounds that can be tested per animal. We developed instrumentation and software that can automatically find adult cardiomyocytes. Cells are detected based on the cell boundary using a Sobel-filter to find the edge information in the field of view. Separately, we detected motion by calculating the variance of intensity for each pixel in the frame throug

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Unruh, H. W., R. Wang, D. Bose, and S. N. Mink. "Does pentobarbital anesthesia depress left ventricular contractility in dogs?" American Journal of Physiology-Heart and Circulatory Physiology 261, no. 3 (1991): H700—H706. http://dx.doi.org/10.1152/ajpheart.1991.261.3.h700.

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Although pentobarbital sodium (NP) anesthesia has been shown to depress left ventricular (LV) contractility in dogs, measurements of LV contractility in previous studies have been made soon after a bolus of NP was given when serum concentrations would be extremely high. In this study, we compared indexes of LV contractility during awake and anesthetized conditions. During anesthesia, measurements were obtained 1 h after an intravenous bolus of NP was given when serum concentrations were approximately 25 mg/l and above that reported to abolish pain. In 13 dogs, subendocardial ultrasonic crystal

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Fry, Christopher H., Andrew Gammie, Marcus John Drake, Paul Abrams, Darryl Graham Kitney, and Bahareh Vahabi. "Estimation of bladder contractility from intravesical pressure-volume measurements." Neurourology and Urodynamics 36, no. 4 (2016): 1009–14. http://dx.doi.org/10.1002/nau.23047.

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Helmes, Michiel, Lu Cao, and Emmy Manders. "Full Automatic High Throughput Cardiomyocyte Calcium and Contractility Measurements." Biophysical Journal 118, no. 3 (2020): 410a. http://dx.doi.org/10.1016/j.bpj.2019.11.2318.

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Menon, Prahlad G., Srilakshmi M. Adhypak, Ronald B. Williams, Mark Doyle, and Robert W. W. Biederman. "Investigating Cardiac MRI Based Right Ventricular Contractility as a Novel Non-Invasive Metric of Pulmonary Arterial Pressure." Clinical Medicine Insights: Cardiology 8s1 (January 2014): CMC.S15711. http://dx.doi.org/10.4137/cmc.s15711.

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Background We test the hypothesis that cardiac magnetic resonance (CMR) imaging-based indices of four-dimensional (4D) (three dimensions (3D) + time) right ventricle (RV) function have predictive values in ascertaining invasive pulmonary arterial systolic pressure (PASP) measurements from right heart catheterization (RHC) in patients with pulmonary arterial hypertension (PAH). Methods We studied five patients with idiopathic PAH and two age and sex-matched controls for RV function using a novel contractility index (CI) for amplitude and phase to peak contraction established from analysis of re

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Myers, David R., Todd Sulchek, and Wilbur Lam. "Nanomechanics of Platelet Contractility." Blood 118, no. 21 (2011): 2202. http://dx.doi.org/10.1182/blood.v118.21.2202.2202.

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Abstract Abstract 2202 Background: Blood clots are composed of fibrin, platelets, and other blood cells and proteins, which interact to prevent hemorrhage. Previous studies on clot formation have shown that the mechanical properties of clots have direct effects on hemostasis and thrombosis, and alterations of those clot mechanics are associated with disease. For example, clots are 50% stiffer and more resistant to dissolution in young patients with post-myocardial infarction (Collet, et al., Arterioscler Thromb Vasc Biol, 2006) than clots from healthy controls. Conversely, clots are softer and

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Engwall, Michael, Kathy Derakhchan, and Hugo Vargas. "Evaluation of a heart rate correction for rat contractility measurements." Journal of Pharmacological and Toxicological Methods 68, no. 1 (2013): e46. http://dx.doi.org/10.1016/j.vascn.2013.01.165.

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Wiederholt, M. "1136 The trabecular meshwork: Lessons from electrophysiological and contractility measurements." Vision Research 35 (October 1995): S56. http://dx.doi.org/10.1016/0042-6989(95)90034-9.

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Wiederholt, M. "The trabecular meshwork: lessons from electrophysio-logical and contractility measurements." Vision Research 35, no. 1 (1995): S56. http://dx.doi.org/10.1016/0042-6989(95)98243-3.

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Stahl, F., A. Lepple-Wienhues, M. Kuppinger, U. Schneider, and M. Wiederholt. "Measurements of intracellular calcium and contractility in human ciliary muscle." Pfl�gers Archiv European Journal of Physiology 418, no. 6 (1991): 531–37. http://dx.doi.org/10.1007/bf00370567.

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Dissertations / Theses on the topic "Contractility measurements"

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Gonçalves, Alexandre Manuel Monteiro. "T3 HORMONE AS AN EFFECTIVE THERAPY FOR HEART FAILURE WITH PRESERVED EJECTION FRACTION: Effects on Ca2+ transients and contractility." Master's thesis, 2018. http://hdl.handle.net/10316/81936.

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Dissertação de Mestrado em Investigação Biomédica apresentada à Faculdade de Medicina<br>A insuficiência cardíaca com fração de ejeção preservada (ICFEP) constitui um frequente problema clínico, mas até hoje, nenhuma intervenção terapêutica parece modular o seu desfecho clínico. Alguns doentes com ICFEP possuem alterações no eixo hormonal da tiroide e é já conhecido o impacto da influência destas hormonas sobre o sistema cardiovascular. Neste projeto, testamos a hipótese de que administração oral preventiva com triiodotironina (T3) pode prevenir o desenvolvimento de ICFEP. Iniciou-se às 14 sem

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Books on the topic "Contractility measurements"

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Dierdorf, Stephen F. Hypocalcemia/Hypercalcemia. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0038.

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Calcium is critical to many vital physiologic functions. These functions include cardiac rhythm and contractility, neuromuscular transmission, and skeletal muscle contractility. 45% of the calcium in the blood is ionized, which is more revalent to the physiologic function of calcium as opposed to the fraction that is bound. Serum ionized calcium levels are closely regulated by the parathyroid gland via calcium-sensing receptors and parathormone secretion. Low or high levels of calcium can result in life-threatening cardiac dysrhythmias and skeletal muscle weakness leading to respiratory failur

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Sidhu, Kulraj S., Mfonobong Essiet, and Maxime Cannesson. Cardiac and vascular physiology in anaesthetic practice. Edited by Jonathan G. Hardman. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0001.

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This chapter discusses key components of cardiovascular physiology applicable to clinical practice in the field of anaesthesiology. From theory development to ground-breaking innovations, the history of cardiac and vascular anatomy, as well as physiology, is presented. Utilizing knowledge of structure and function, parameters created have allowed adequate patient clinical assessment and guided interventions. A review of concepts reveals the impact of multiple physiological variables on a patient’s haemodynamic state and the need for more accurate and efficient measurements. In particular, it i

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Cosyns, Bernard, Thor Edvardsen, Krasimira Hristova, and Hyung-Kwan Kim. Left ventricle: systolic function. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0020.

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The assessment of left ventricular (LV) systolic function is one of the most important parts of correct diagnosis, selection of treatment strategy or medications, and prediction of prognosis. Although cardiac magnetic resonance imaging is generally accepted as the gold standard in vivo imaging modality for assessing LV systolic function, its practical use is limited due to its limited availability, high cost, and the presence of conditions precluding its performance such as a pacemaker, claustrophobia, and severe arrhythmia. Thus, transthoracic echocardiography is a first-line imaging modality

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Book chapters on the topic "Contractility measurements"

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Zuppinger, Christian. "Edge-Detection for Contractility Measurements with Cardiac Spheroids." In Methods in Pharmacology and Toxicology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6661-5_11.

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Zuppinger, Christian. "Measurement of Contractility and Calcium Release in Cardiac Spheroids." In Methods in Molecular Biology. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9030-6_4.

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Paukkunen, Mikko, and Matti Linnavuo. "Precordial Vibrations." In Advances in Systems Analysis, Software Engineering, and High Performance Computing. IGI Global, 2014. http://dx.doi.org/10.4018/978-1-4666-6252-0.ch011.

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In the era of medicine, the heart and cardiovascular system has become one of the standard observation targets. Palpation and auscultation in the precordial area is performed as part of the regular physical examination to detect possible cardiovascular and pulmonary problems. However, due to the large number of people suffering from cardiovascular problems, labor-intensive methods such as auscultation might be inefficient in preventive cardiovascular condition screening. Seismocardiography (SCG) could have the potential to be a part of the solution to this problem. SCG is one of many modalities of cardiac-induced vibration measurements, and it has been shown to be of use in detecting coronary artery disease and assessing myocardial contractility. Lately, due to advances in sensor technologies, the SCG measurement is being developed by introducing three-dimensional measurements. Three-dimensional approach is considered to yield more information about the cardiovascular system than any single uniaxial approach. In conclusion, SCG seems to have the potential to offer a complementary view to cardiovascular function and a cost-effective method for screening of cardiovascular diseases. SCG is explored in this chapter.

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Hoyler, Marguerite, and Natalia S. Ivascu. "Postoperative Right Ventricular Failure." In Cardiothoracic Critical Care. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190082482.003.0011.

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This chapter examines postoperative right ventricular (RV) failure. RV failure is not uncommon following cardiac surgery and often portends a worse clinical outcome. After establishing the diagnosis of RV failure, the central goal of treatment is to increase RV function in order to achieve adequate left ventricular preload and cardiac output. Key management points include decreasing RV volume and preload, increasing RV contractility, reducing RV afterload, maintaining normal rate and rhythm, and supporting RV and systemic perfusion. Diuresis, inodilators and inopressors, and inhaled direct pulmonary vasodilators are mainstays of treatment. Meanwhile, serial transthoracic echocardiogram and central venous pressure measurements, as well as markers of cardiac output and systemic perfusion, are critical for guiding RV failure management.

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Broscheit, Jens. "Measurement of Myocardial Contractility in the Ischemic Heart – A Disease Immanent Uncertainty." In Novel Strategies in Ischemic Heart Disease. InTech, 2012. http://dx.doi.org/10.5772/31608.

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Conference papers on the topic "Contractility measurements"

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Garcia-Sanchez, Tomas, Esther Jorge, Gerard Amoros-Figueras, Ramon Bragos, Joan Cinca, and Javier Rosell-Ferrer. "Myocardial contractility assessed by dynamic electrical impedance measurements during dobutamine stress." In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7319893.

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Zhang, Qiang, Ashwin Iyer, Kang Kim, and Nitin Sharma. "Volitional Contractility Assessment of Plantar Flexors by Using Non-invasive Neuromuscular Measurements." In 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob). IEEE, 2020. http://dx.doi.org/10.1109/biorob49111.2020.9224298.

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Rodriguez, Marita L., Charles E. Murry, and Nathan J. Sniadecki. "Assessment of Induced Pluripotent Stem Cell-Derived Cardiomyocyte Contractility Using Micropost Arrays." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14640.

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Cardiovascular stem cell therapies have shown increasing promise as a potential therapeutic means for reversing the effects of a myocardial infarction [1]. Out of the currently available sources of human stem cells, human induced pluripotent stem cells (hiPSCs) are very promising in that: the number of cell lines that can be induced to the pluripotent state is extremely vast, they serve as a potential source for patient-specific cardiomyocytes, and their use is non-controversial. However, before they can be used feasibly in a clinical setting, the functional engraftment of these cells into the

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Kolli, Kranthi K., Mohamed Effat, Tarek Helmy, et al. "Influence of Heart Rate and Contractility on Coronary Diagnostic Parameters With Normal Microvasculature in Porcine Model." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19199.

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Invasive guide-wire measurements are used to assess coronary lesion severity under clinical settings. The objective of the present research is to determine the influence of heart rate (HR) and contractility (CY) on fractional flow reserve (FFR; the ratio of distal pressure to proximal pressure at a stenotic section) and pressure drop coefficient (CDPe; the ratio of trans-stenotic pressure drop to distal dynamic pressure). In-vivo experiments were performed on eight Yorkshire pigs, to evaluate the diagnostic parameters for the conditions “CY<1100 mmHg/sec” and “CY>1100 mmHg/sec,” and for

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Ruggeri, Alfredo, Andrea Logiudice, Werner Rainera, and Andrea Erlicherh. "A new approach for a minimally invasive measurement of cardiac contractility via ventricle elastance." In Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering'. IEEE, 1997. http://dx.doi.org/10.1109/iembs.1997.754517.

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Weafer, P., N. Reynolds, W. Ronan, E. Dowling, S. Jarvis, and P. McGarry. "Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14793.

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Dynamic mechanical loading is essential for cell function and tissue maintenance. In an effort to characterize the response of cells to cyclic deformation several in vitro studies have relied on the testing of large populations of cells seeded on 2D substrates or in 3D scaffolds and gels. However, such studies do not allow for the measurement of forces actively generated at a single cell level. In the present study deformation controlled cyclic loading experiments are performed on single osteoblasts at the whole cell level using a modified AFM system [1,2]. In addition to untreated cells, expe

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