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Journal articles on the topic 'Control orchestration protocol'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Mayoral, Arturo, Ricard Vilalta, Raul Muñoz, et al. "Control Orchestration Protocol: Unified Transport API for Distributed Cloud and Network Orchestration." Journal of Optical Communications and Networking 9, no. 2 (2017): A216. http://dx.doi.org/10.1364/jocn.9.00a216.

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Mayoral, Arturo, Ricard Vilalta, Raül Muñoz, et al. "Control Orchestration Protocol: unified transport API for distributed cloud and network orchestration." JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING 9, no. 2 (2017): A216—A222. https://doi.org/10.1364/JOCN.9.00A216.

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In the context of the fifth generation of mobile technology (5G), multiple technologies will converge into a unified end-to-end system. For this purpose, software defined networking (SDN) is proposed, as the control paradigm will integrate all network segments and heterogeneous optical and wireless network technologies together with massive storage and computing infrastructures. The control orchestration protocol is presented as a unified transport application programming interface solution for joint cloud/network orchestration, allowing interworking of heterogeneous control planes to provide

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Casellas, Ramon, Ricardo Martínez, Raül Muñoz, Ricard Vilalta, and Lei Liu. "Control and Orchestration of Multidomain Optical Networks With GMPLS as Inter-SDN Controller Communication." Journal of Optical Communications and Networking 7, no. 11 (2015): B46—B54. https://doi.org/10.5281/zenodo.46114.

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Emerging use cases, such as the orchestration of heterogeneous domains or the interconnection of remote data centers, require the design of new network control, management, and orchestration architectures that are adapted to the requirements associated with end-to-end services. This heterogeneity, stemming from actual deployments, is related to the involved data and control technologies or due to network segmentation. It is acknowledged that, in these scenarios, the deployment of a single software-defined networking (SDN) controller may not be practical or may have fundamental limitations, in

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Casellas, Ramon, Ricardo Martínez, Ricard Vilalta, and Raül Muñoz. "Control, Management and Orchestration of Optical Networks: Evolution, Trends and Challenges." Journal of Lightwave Technology 36, no. 7 (2018): 1390–402. https://doi.org/10.1109/JLT.2018.2793464.

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Automating the provisioning of telecommunications services, deployed over a heterogeneous infrastructure (in terms of domains, technologies, and management platforms), remains a complex task, yet driven by the constant need to reduce costs and service deployment time. This is more so, when such services are increasingly conceived around interconnected functions and require allocation of computing, storage, and networking resources. This automation drives the development of service and resource orchestration platforms that extend, integrate, and build on top of existing approaches, macroscopica

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Zabasta, A., N. Kunicina, and K. Kondratjevs. "Transition from Legacy to Connectivity Solution for Infrastructure Control of Smart Municipal Systems." Latvian Journal of Physics and Technical Sciences 54, no. 3 (2017): 13–22. http://dx.doi.org/10.1515/lpts-2017-0016.

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Abstract Collaboration between heterogeneous systems and architectures is not an easy problem in the automation domain. By now, utilities and suppliers encounter real problems due to underestimated costs of technical solutions, frustration in selecting technical solutions relevant for local needs, and incompatibilities between a plenty of protocols and appropriate solutions. The paper presents research on creation of architecture of smart municipal systems in a local cloud of services that apply SOA and IoT approaches. The authors of the paper have developed a broker that applies orchestration

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Mayoral, Arturo, Raül Muñoz, Ricard Vilalta, Ramon Casellas, Ricardo Martínez, and Víctor López. "Need for a Transport API in 5G for Global Orchestration of Cloud and Networks Through a Virtualized Infrastructure Manager and Planner." Journal of Optical Communications and Networking 9, no. 1 (2017): A55—A62. https://doi.org/10.1364/JOCN.9.000A55.

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The new 5G paradigm seeks for a scalable architecture that is able to efficiently manage the increasing volume of traffic generated by smart devices to be processed in a distributed cloud infrastructure. To this end, coordinated management of the network and the cloud resources forming an end-to-end system is of great importance. Software defined networking and network function virtualization architectures are the key enablers for integrating network and cloud resources, enabling cross optimization on both sides. This optimization requires efficient resource allocation algorithms, which take i

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Casellas, Ramon, Oscar González, Francesco Paolucci, et al. "A Control Plane Architecture for Multi-Domain Elastic Optical Networks: the view of the IDEALIST project." IEEE Communications Magazine, 54, no. 8 (2016): 136–43. https://doi.org/10.1109/MCOM.2016.7537188.

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A key objective of the IDEALIST project included the design and implementation of a GMPLS and PCE-based control plane for multi-vendor and multi-domain flexi-grid EON, leveraging the project advances in optical switching and transmission technology, an enabling interoperable deployment. A control plane, relying on a set of entities, interfaces, and protocols, provides the automation of the provisioning, recovery, and monitoring of end-to-end optical connections. This article provides an overview of the implemented architecture. We present the macroscopic system along with the core functional b

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Khalid, S., H. M. Abdullah, and S. Z. Ahmad. "Analysis of Transmission Control Protocol Incast over Large-scale HPC Clusters." Nucleus 58, no. 1-4 (2022): 1–8. https://doi.org/10.71330/nucleus.58.01-4.1165.

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The lifecycle of large-scale applications executing on High-Performance Computing (HPC) clusters involves massive use of transmission control protocol (TCP) while performing orchestration for job completion on multiple compute resources. As the HPC clusters involve large local area network communication for distributing jobs over compute and data nodes, the core network fabric in cluster architecture faces heavy workloads of TCP sessions; causing more than average packet drop events. This results in the poor TCP throughput; thus reducing the overall performance indices of the cluster. In this

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Kim, Taehun, Hojung Kim, SeungKeun Cho, YongSeong Kim, ByungKwen Song, and Jincheol Kim. "Real-Time Kubernetes-Based Front-End Processor for Smart Grid." Electronics 14, no. 12 (2025): 2377. https://doi.org/10.3390/electronics14122377.

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In Supervisory Control and Data Acquisition (SCADA) systems, central to industrial automation and control systems, the Front-end Processor (FEP) facilitates seamless communication between field control devices and central management systems. As the Industrial Internet of Things (IIoT) and Industry 4.0 centered on the smart factory paradigm gain traction, conventional FEPs are increasingly showing limitations in various aspects. To address these issues, Data Distribution Service, a real-time communication middleware, and Kubernetes, a container orchestration platform, have garnered attention. H

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Muñoz, Raül, Ricard Vilalta, Ramon Casellas, et al. "Integrated SDN/NFV management and orchestration architecture for dynamic deployment of virtual SDN control instances for virtual tenant networks." Journal of Optical Communications and Networking 7, no. 11 (2015): B62—B70. https://doi.org/10.5281/zenodo.46115.

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Software-defined networking (SDN) and network function virtualization (NFV) have emerged as the most promising candidates for improving network function and protocol programmability and dynamic adjustment of network resources. On the one hand, SDN is responsible for providing an abstraction of network resources through well-defined application programming interfaces. This abstraction enables SDN to perform network virtualization, that is, to slice the physical infrastructure and create multiple coexisting application-specific virtual tenant networks (VTNs) with specific quality-of-service and

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Patni, Sakshi, and Joohyung Lee. "EdgeGuard: Decentralized Medical Resource Orchestration via Blockchain-Secured Federated Learning in IoMT Networks." Future Internet 17, no. 1 (2024): 2. https://doi.org/10.3390/fi17010002.

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The development of medical data and resources has become essential for enhancing patient outcomes and operational efficiency in an age when digital innovation in healthcare is becoming more important. The rapid growth of the Internet of Medical Things (IoMT) is changing healthcare data management, but it also brings serious issues like data privacy, malicious attacks, and service quality. In this study, we present EdgeGuard, a novel decentralized architecture that combines blockchain technology, federated learning, and edge computing to address those challenges and coordinate medical resources

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Casellas, Ramon, Raul Muñoz, Ricardo Martínez, et al. "Overarching Control of Flexi Grid Optical Networks: Interworking of GMPLS and OpenFlow Domains." IEEE/OSA Journal of Lightwave Technology 33, no. 5 (2015): 1054–62. https://doi.org/10.5281/zenodo.47522.

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Optical transport networks provide transport, multiplexing, routing, management, supervision, and survivability of optical channels. Within a flexible dense wavelength division multiplexing grid, the optical spectrum can be allocated in multiples of a width granularity, depending on the client signal rate and modulation format. A control plane (CP) can be used for efficient and dynamic provisioning and recovery of flexi-grid connections. Two main CP architectures coexist, with common functions like addressing, automatic topology discovery, network abstraction, path computation, and connection

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Huang, Xiao, Xiaofeng Wang, Yuan Liu, and Qingsong Xue. "A Distributed Traffic Replay Framework for Network Emulation." Information 14, no. 2 (2023): 59. http://dx.doi.org/10.3390/info14020059.

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Traffic replay can effectively improve the fidelity of network emulation and can support emerging network verification and network security evaluation. A distributed traffic replay framework for network emulation, named DTRF, is designed for large-scale and high-fidelity network traffic emulation on the cloud platform. A fast traffic replay strategy bypassing the kernel is proposed to improve the traffic replay performance in the single node by alleviating the problem of high overhead from the kernel protocol stack. To conveniently expand the emulation scale, an extendable method of workflow o

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Shariat, Mehrdad, Ömer Bulakci, Antonio De Domenico, et al. "A Flexible Network Architecture for 5G Systems." Wireless Communications and Mobile Computing 2019 (February 11, 2019): 1–19. http://dx.doi.org/10.1155/2019/5264012.

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In this paper, we define a flexible, adaptable, and programmable architecture for 5G mobile networks, taking into consideration the requirements, KPIs, and the current gaps in the literature, based on three design fundamentals: (i) split of user and control plane, (ii) service-based architecture within the core network (in line with recent industry and standard consensus), and (iii) fully flexible support of E2E slicing via per-domain and cross-domain optimisation, devising inter-slice control and management functions, and refining the behavioural models via experiment-driven optimisation. The

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Anton, Simon D. Duque. "Software-Bus-Toolchain (SBT): Introducing a Versatile Method for Quickly Implementing (I)IoT-Scenarios." Future Internet 16, no. 7 (2024): 237. http://dx.doi.org/10.3390/fi16070237.

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The Internet of Things (IoT) has become ubiquitous. IoT devices are applied in a multitude of applications, e.g., in smart home scenarios, building automation, smart energy and smart cities, healthcare, and industrial environments. Fast and efficient implementation and roll-out of IoT devices is a critical factor for successs and acceptance of IoT devices. At the same time, the variety of hardware platforms that can be used for IoT applications, as well as the number of IoT orchestration platforms is increasing. Finding the right combination of tooling and hardware is not trivial, but essentia

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Vaquero-Melchor, Diego, Ana M. Bernardos, and Luca Bergesio. "SARA: A Microservice-Based Architecture for Cross-Platform Collaborative Augmented Reality." Applied Sciences 10, no. 6 (2020): 2074. http://dx.doi.org/10.3390/app10062074.

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Augmented Reality (AR) functionalities may be effectively leveraged in collaborative service scenarios (e.g., remote maintenance, on-site building, street gaming, etc.). Standard development cycles for collaborative AR require to code for each specific visualization platform and implement the necessary control mechanisms over the shared assets. in order to face this challenge, this paper describes SARA, an architecture to support cross-platform collaborative Augmented Reality applications based on microservices. The architecture is designed to work over the concept of collaboration models whic

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Seery, Tara Elisabeth, Chaitali Singh Nangia, Heidi Ann McKean, et al. "Promising survival and disease control in third-line or greater metastatic or locally advanced pancreatic cancer patients following chemo-radiation and novel combination of aldoxorubicin, N-803 IL-15 superagonist, and PDL1- NK cell therapy." Journal of Clinical Oncology 40, no. 4_suppl (2022): 582. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.582.

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582 Background: Pancreatic cancer claimed an estimated 47,050 lives in the USA in 2020, with an expected median overall survival (OS) of 3 months in 3rd line. (Manax ASCO GI 2019), with no evidence of disease control in these late stage patients. We hypothesize that effective response against pancreatic cancer requires orchestration of both the innate and adaptive immune system to accomplish immunogenic cell death with survival benefit. Herein we report the first results of a novel combination immunotherapy protocol of low-dose chemoradiation, cytokine-induced NK and T cell activation via N-80

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Dimpy Jindal, Et al. "Smart Ontology Framework for Multi-Tenant Cloud Architecture." International Journal on Recent and Innovation Trends in Computing and Communication 11, no. 9 (2023): 3506–14. http://dx.doi.org/10.17762/ijritcc.v11i9.9563.

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The exponential growth of data complexity in an era marked by the rapid expansion of the computer environment has led to an increase in the demand for scalable and effective systems. The crucial stage of data management, which acts as a vital conduit for accelerating the processing of enormous amounts of data, is at the centre of this paradigm. Scientific workflows must be coordinated in order to orchestrate the management of large datasets within this complex ecosystem. These workflows differ from generic workflows in that they involve a complex interplay of scheduling, algorithms, data flow,

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Seery, Tara Elisabeth, Chaitali Singh Nangia, Phillip D. Reid, et al. "Overall survival in patients with metastatic or locally advanced pancreatic cancer following chemoradiation with novel combination of aldoxorubicin, N-803 IL-15 superagonist, and PDL1- NK cell therapy." Journal of Clinical Oncology 41, no. 4_suppl (2023): 720. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.720.

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720 Background: Pancreatic cancer claimed an estimated 47,050 lives in the USA in 2020, with an expected median overall survival (OS) of 3 months in 3rd line. (Manax ASCO GI 2019), with no evidence of disease control in these late stage patients. We hypothesize that effective response against pancreatic cancer requires orchestration of both the innate and adaptive immune system to accomplish immunogenic cell death with survival benefit. Herein we report updated results of the fully enrolled cohort of a novel combination immunotherapy protocol of low-dose chemoradiation, cytokine-induced NK and

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Miller, Jason, Min Luo, Hua Wang, et al. "P857 ONM-500 – a novel STING-activating therapeutic nanovaccine platform for cancer immunotherapy." Journal for ImmunoTherapy of Cancer 8, Suppl 1 (2020): A7—A8. http://dx.doi.org/10.1136/lba2019.11.

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BackgroundEfficacy of cancer vaccines requires the induction of tumor antigen-specific cytotoxic T-lymphocytes (CTL) to effectively clear established tumors. Orchestration of antigen presentation, co-stimulatory signaling, and innate cytokine signals are necessary steps for tumor-specific T-cell activation. The ONM-500 nanovaccine platform1-2 utilizes a novel pH-sensitive polymer that forms an antigen-encapsulating nanoparticle and functions both as a carrier for antigen delivery of both peptide and protein antigens to dendritic cells and acts as an adjuvant, activating the stimulator on inter

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Sunil Sudhakaran. "Security-embedded orchestration for regulatory-heavy industries on cloud platforms." World Journal of Advanced Engineering Technology and Sciences 15, no. 3 (2025): 961–74. https://doi.org/10.30574/wjaets.2025.15.3.0991.

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The advent of cloud computing has revolutionized the way businesses operate, especially in regulatory-heavy industries that must adhere to stringent compliance requirements. However, ensuring the security and compliance of cloud orchestration frameworks remains a significant challenge. This paper proposes a novel model for security-embedded orchestration, specifically designed to address the security and compliance needs of industries such as finance, healthcare, and telecommunications. The model integrates a series of security controls and compliance validation processes directly into the orc

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Narne, Harish, and Sandip Dholakia. "Adaptive Security Model for Cloud Platforms Based on Information Security and Cryptographic Protocols." International Journal of Computing and Engineering 7, no. 2 (2025): 10–20. https://doi.org/10.47941/ijce.2591.

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Purpose: This paper proposes an adaptive security model designed for cloud platforms, integrating information security principles and cryptographic protocols to address evolving cybersecurity threats. The model ensures dynamic security control adjustments based on real-time risk assessments to protect enterprise applications and business operations. Methodology: The proposed model employs continuous monitoring, intelligent threat detection, and automated responses to proactively mitigate risks. It integrates cryptographic techniques such as AES, RSA, and elliptic-curve cryptography to secure d

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Sathesh Suseendran. "Automation and Orchestration in NVMe over Fibre Channel Environments: A Comprehensive Analysis." World Journal of Advanced Engineering Technology and Sciences 15, no. 3 (2025): 2334–40. https://doi.org/10.30574/wjaets.2025.15.3.1096.

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Non-Volatile Memory Express over Fibre Channel (NVMe-FC) represents a significant advancement in enterprise storage technology, delivering substantial performance improvements compared to traditional protocols while maintaining compatibility with existing infrastructure. Implementing comprehensive automation and orchestration frameworks has become essential for organizations seeking to maximize the benefits of NVMe-FC deployments. Automated provisioning dramatically reduces deployment times and configuration errors while ensuring optimal performance through precise parameter settings. API inte

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Tanaka, H., Y. Okada, S. Nakayamada, et al. "OP0001 DECONVOLUTING IMMUNOLOGICAL AND CLINICAL HETEROGENEITY ACROSS AUTOIMMUNE RHEUMATIC DISEASES BY COHORT-WIDE IMMUNO-PHENOTYPING." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1.2–1. http://dx.doi.org/10.1136/annrheumdis-2023-eular.4390.

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BackgroundAutoimmune rheumatic diseases (AIRDs) are systemic but heterogeneous diseases characterized by orchestration of disrupted self-tolerance of immune systems. We face a challenge in characterizing clinical immune features and selecting best treatment strategy of the AIRD patients.ObjectivesDeconvolution of immunological and clinical heterogeneity within and across AIRDs is an essential step towards implementation of personalized medicine. Immuno-phenotypes, immune-related cell types in peripheral blood mononuclear cells quantified by flow-cytometry analysis, can less invasively describe

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STINE, JOHN A., GUSTAVO DE VECIANA, KEVIN H. GRACE, and ROBERT C. DURST. "ORCHESTRATING SPATIAL REUSE IN WIRELESS AD HOC NETWORKS USING SYNCHRONOUS COLLISION RESOLUTION (SCR)." Journal of Interconnection Networks 03, no. 03n04 (2002): 167–95. http://dx.doi.org/10.1142/s0219265902000616.

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We propose a novel medium access control protocol for ad hoc wireless networks data to send can contend simultaneously for the channel. Nodes contend for access using a synchronous signaling mechanism that achieves two objectives: it arbitrates contentions locally and it selects a subset of nodes across the network that attempt to transmit simultaneously. The subset of nodes that survive the signaling mechanism can be viewed as an orchestrated set of transmissions that are spatially reusing the channel shared by the nodes. Thus the 'quality' of the subset of nodes selected by the signaling mec

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Naresh Enjamuri. "The New API Economy: Advances in scalable platforms and process automation." World Journal of Advanced Research and Reviews 26, no. 2 (2025): 3491–500. https://doi.org/10.30574/wjarr.2025.26.2.2049.

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This article explores the transformative evolution of application programming interfaces (APIs) from basic integration tools to sophisticated ecosystems powering enterprise digital transformation. It examines how cutting-edge advances in distributed API management, artificial intelligence optimization, specialized protocols, and process automation are reshaping the technological landscape. The emergence of API mesh architectures provides enhanced traffic control across multi-cloud environments while implementing zero-trust security principles. Meanwhile, AI capabilities enable predictive perfo

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Cristancho, Pilar, Jacinda Berger, Lojine Kamel, Manuela Araque, Barch Deanna, and Lenze Eric. "3551 Intermittent Theta Burst Stimulation to Relieve Depression and Executive Function impairment in older adults." Journal of Clinical and Translational Science 3, s1 (2019): 47–48. http://dx.doi.org/10.1017/cts.2019.113.

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OBJECTIVES/SPECIFIC AIMS: The objective of the study is to examine the ability of iTBS to improve depression and executive impairment in depressed older adults. If effective, this treatment will have the potential to improve the quality of life in LLD. METHODS/STUDY POPULATION: From 12- 2016 to date older adults (60 – 85 y/o) in a major depressive episode, with evidence of executive dysfunction (on the NIH Tool Box battery) were enrolled. iTBS protocol: This brief paradigm (3 min 9 seconds duration) was administered on weekdays for four weeks (20 sessions total). Stimulation intensity was set

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ul Hassan, Mahmood, Amin A. Al-Awady, Abid Ali, et al. "ANN-Based Intelligent Secure Routing Protocol in Vehicular Ad Hoc Networks (VANETs) Using Enhanced AODV." Sensors 24, no. 3 (2024): 818. http://dx.doi.org/10.3390/s24030818.

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A vehicular ad hoc network (VANET) is a sophisticated wireless communication infrastructure incorporating centralized and decentralized control mechanisms, orchestrating seamless data exchange among vehicles. This intricate communication system relies on the advanced capabilities of 5G connectivity, employing specialized topological arrangements to enhance data packet transmission. These vehicles communicate amongst themselves and establish connections with roadside units (RSUs). In the dynamic landscape of vehicular communication, disruptions, especially in scenarios involving high-speed vehi

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Bertoli, Annalisa, Andrea Cervo, Carlo Alberto Rosati, and Cesare Fantuzzi. "Smart Node Networks Orchestration: A New E2E Approach for Analysis and Design for Agile 4.0 Implementation." Sensors 21, no. 5 (2021): 1624. http://dx.doi.org/10.3390/s21051624.

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The field of cyber-physical systems is a growing IT research area that addresses the deep integration of computing, communication and process control, possibly with humans in the loop. The goal of such area is to define modelling, controlling and programming methodologies for designing and managing complex mechatronics systems, also called industrial agents. Our research topic mainly focuses on the area of data mining and analysis by means of multi-agent orchestration of intelligent sensor nodes using internet protocols, providing also web-based HMI visualizations for data interpretability and

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Weiss, Eyal, Shir Caplan, Kobi Horn, and Moshe Sharabi. "Real-Time Defect Detection in Electronic Components during Assembly through Deep Learning." Electronics 13, no. 8 (2024): 1551. http://dx.doi.org/10.3390/electronics13081551.

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This paper introduces a pioneering method for real-time image processing in electronic component assembly, revolutionizing quality control in manufacturing. By promptly capturing images from pick-and-place machines during the interval between component pick-up and mounting, defects are identified and promptly addressed in line. This proactive approach ensures that defective components are rejected before mounting, effectively preventing issues from ever occurring, thus significantly enhancing efficiency and reliability. Leveraging rapid network protocols such as gRPC and orchestration via Kube

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Abdulkadhim, Mustafa, Noor Qusay, and Aymen M. Al-Kadhimi. "Design and simulation of a software defined networkingenabled smart switch, for internet of things-based smart grid." Indonesian Journal of Electrical Engineering and Computer Science 25, no. 2 (2022): 780–87. https://doi.org/10.11591/ijeecs.v25.i2.pp780-787.

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Using sustainable energy is the future of our planet earth, this became not only economically efficient but also a necessity for the preservation of life on earth. Because of such necessity, smart grids became a very important issue to be researched. Many literatures discussed this topic and with the development of internet of things (IoT) and smart sensors, smart grids are developed even further. On the other hand, software defined networking is a technology that separates the control plane from the data plan of the network. It centralizes the management and the orchestration of the network t

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Awa, Daniel Ndzingu, and Mbunkah Daniel Achukwi. "Livestock pathology in the central African region: some epidemiological considerations and control strategies." Animal Health Research Reviews 11, no. 2 (2010): 235–44. http://dx.doi.org/10.1017/s1466252309990077.

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AbstractDisease consistently features among the major constraints of livestock production in the central African region, orchestrating important economic losses. This article reviews livestock diseases of economic importance, including foot-and-mouth disease, trypanosomosis and dermatophilosis in cattle, peste des petits ruminants and gastrointestinal helminthosis in sheep and goats, and Newcastle disease in poultry. Some aspects of epidemiology such as pathogen identification, prevalence and risk factors are examined in the light of research findings in the region. Control tools such as vacci

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Abdulkadhim, Mustafa, Noor Qusay Abdulmuhsen, and Aymen M. Al-Kadhimi. "Design and simulation of a software defined networking-enabled smart switch for internet of things-based smart grid." Indonesian Journal of Electrical Engineering and Computer Science 25, no. 2 (2022): 780. http://dx.doi.org/10.11591/ijeecs.v25.i2.pp780-787.

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Using sustainable energy is the future of our planet earth, this became not only economically efficient but also a necessity for the preservation of life on earth. Because of such necessity, smart grids became a very important issue to be researched. Many literatures discussed this topic and with the development of internet of things (IoT) and smart sensors, smart grids are developed even further. On the other hand, software defined networking is a technology that separates the cntrol plane from the data plan of the network. It centralizes the management and the orchestration of the network ta

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Crippa, Stefania, Ludovica Santi, Roberto Bosotti, Giulia Porro, and Maria Ester Bernardo. "Bone Marrow-Derived Mesenchymal Stromal Cells: A Novel Target to Optimize Hematopoietic Stem Cell Transplantation Protocols in Hematological Malignancies and Rare Genetic Disorders." Journal of Clinical Medicine 9, no. 1 (2019): 2. http://dx.doi.org/10.3390/jcm9010002.

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Mesenchymal stromal cells (MSCs) are crucial elements in the bone marrow (BM) niche where they provide physical support and secrete soluble factors to control and maintain hematopoietic stem progenitor cells (HSPCs). Given their role in the BM niche and HSPC support, MSCs have been employed in the clinical setting to expand ex-vivo HSPCs, as well as to facilitate HSPC engraftment in vivo. Specific alterations in the mesenchymal compartment have been described in hematological malignancies, as well as in rare genetic disorders, diseases that are amenable to allogeneic hematopoietic stem cell tr

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Cimino, Maura, Paula Parreira, Victoria Leiro, et al. "Enhancement of hMSC In Vitro Proliferation by Surface Immobilization of a Heparin-Binding Peptide." Molecules 28, no. 8 (2023): 3422. http://dx.doi.org/10.3390/molecules28083422.

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The use of human Mesenchymal Stem Cells (hMSC) as therapeutic agents for advanced clinical therapies relies on their in vitro expansion. Over the last years, several efforts have been made to optimize hMSC culture protocols, namely by mimicking the cell physiological microenvironment, which strongly relies on signals provided by the extracellular matrix (ECM). ECM glycosaminoglycans, such as heparan-sulfate, sequester adhesive proteins and soluble growth factors at the cell membrane, orchestrating signaling pathways that control cell proliferation. Surfaces exposing the synthetic polypeptide p

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Jongtaveesataporn, Aimrudee, and Shingo Takada. "Combining the Strengths of BPEL and Mule ESB." International Journal of Software Engineering and Knowledge Engineering 24, no. 03 (2014): 347–90. http://dx.doi.org/10.1142/s0218194014500144.

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Service Oriented Architecture (SOA) provides an application framework which integrates variety of technology services in a loosely coupled way. Mule Enterprise Service Bus (ESB) is a widely-used ESB product that provides important functions such as message routing, message transformation, protocol-mediation, and event handling. These functions enable Mule ESB to integrate services implemented on various platforms and technologies. However, Mule ESB does not support business logic at all. Another approach to integrate services is to use a business process language such as BPEL (Business Process

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Researcher. "OPTIMIZING MULTI-TENANT SD-WAN DEPLOYMENTS: AN INTEGRATED APPROACH TO SECURITY, PERFORMANCE, AND REGULATORY COMPLIANCE." International Journal of Computer Engineering and Technology (IJCET) 15, no. 6 (2024): 1467–81. https://doi.org/10.5281/zenodo.14506771.

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<em>The widespread adoption of Software-Defined Wide Area Networks (SD-WAN) has led to multi-tenant cloud-hosted deployments, presenting unique challenges in balancing security, performance, and regulatory compliance. This article presents a comprehensive framework for addressing these challenges through empirical analysis of implementations across diverse enterprise environments. The article examines critical security considerations, including data isolation, access control management, and shared infrastructure risks, while proposing robust mitigation strategies through network segmentation a

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Jangeed, Denis, Idrish Mohammad, and Jitendra Patel. "SENSOR BASED SMART TRAFFIC LIGHT CONTROL SYSTEM." International Journal of Technical Research & Science 9, Spl (2024): 27–35. http://dx.doi.org/10.30780/specialissue-iset-2024/022.

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The Smart traffic light control system (STLCS) is a pioneering initiative aimed at addressing the complex challenges inherent in contemporary urban traffic management. As cities worldwide grapple with escalating issues such as traffic congestion, safety hazards, and environmental degradation, the urgency for innovative solutions has never been more pronounced. The STLCS offers a multifaceted approach, harnessing the power of state-of-the-art technologies such as sensor-based cameras, intelligent traffic lights, and sophisticated real-time data analytics. Central to the functionality of the STL

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Jin, Xinmin, Jian Teng, and Jiaji Chen. "IoT-Edge Hybrid Architecture with Cross-Modal Transformer and Federated Manifold Learning for Safety-Critical Gesture Control in Adaptive Mobility Platforms." Future Internet 17, no. 7 (2025): 271. https://doi.org/10.3390/fi17070271.

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This research presents an IoT-empowered adaptive mobility framework that integrates high-dimensional gesture recognition with edge-cloud orchestration for safety-critical human–machine interaction. The system architecture establishes a three-tier IoT network: a perception layer with 60 GHz FMCW radar and TOF infrared arrays (12-node mesh topology, 15 cm baseline spacing) for real-time motion tracking; an edge intelligence layer deploying a time-aware neural network via NVIDIA Jetson Nano to achieve up to 99.1% recognition accuracy with latency as low as 48 ms under optimal conditions (typical

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Kumar, Nishant N., and Ms Priya Panchal. "Building a Secure IoT Platform for Smart Home Automation: A Comprehensive Integration." International Journal for Research in Applied Science and Engineering Technology 12, no. 1 (2024): 302–9. http://dx.doi.org/10.22214/ijraset.2024.57917.

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Abstract: The creation and use of a novel Internet ofThings (IoT) platform designed for smart home automation arepresented in this research study. The platform combines powerful hardware elements with cutting-edge software technologies. It makes use of Docker ptimization on, an Ubuntu-based Linux server, and essential utilities like Traefik, MySQL, Node-RED, Mosquitto, Adminer, and InfluxDB. The infrastructure is painstakingly built to provide scalable deployment, effective data management, and smooth communication. The core of the technique is the creation of a Linux server running Ubuntu. A

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Fu, Chunle, Bailing Wang, Hongri Liu, and Wei Wang. "Software-Defined Virtual Private Network for SD-WAN." Electronics 13, no. 13 (2024): 2674. http://dx.doi.org/10.3390/electronics13132674.

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Software-Defined Wide Area Networks (SD-WANs) are an emerging Software-Defined Network (SDN) technology to reinvent Wide Area Networks (WANs) for ubiquitous network interconnections in cloud computing, edge computing, and the Internet of Everything. The state-of-the-art overlay-based SD-WANs are simply conjunctions of Virtual Private Network (VPN) and SDN architecture to leverage the controllability and programmability of SDN, which are only applicable for specific platforms and do not comply with the extensibility of SDN. This paper motivates us to refactor traditional VPNs with SDN architect

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Chyad, Haitham Salman, Raniah Ali Mustafa, and Dena Nadir George. "Cloud resources modelling using smart cloud management." Bulletin of Electrical Engineering and Informatics 11, no. 2 (2022): 1134–42. http://dx.doi.org/10.11591/eei.v11i2.3286.

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Cloud computing complexity is growing rapidly with the advancements that it is witnessing. It has created a requirement to simplify the process of configuring cloud and re-configuring it when required, it also involves tasks like auto scaling of infrastructure, elastic computing and maintaining the health of the servers. The proposed method introduces a smart cloud management using knowledge base, which models the resources of cloud; it handles service level agreement and its evaluations. The proposed knowledge base supports representational state transfer (REST/RESTful) services to store and

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Kamala Aliyeva, Rashid Jafarov, Kamala Aliyeva, Rashid Jafarov. "SAFETY CONTROL SYSTEMS FOR ETHYLENE PRODUCTION." PAHTEI-Procedings of Azerbaijan High Technical Educational Institutions 35, no. 12 (2023): 206–13. http://dx.doi.org/10.36962/pahtei35122023-206.

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Ethylene production is a cornerstone of the petrochemical industry, with a global demand that continues to rise. Ensuring efficient, safe, and environmentally responsible ethylene production processes is paramount. Ethylene production control systems, encompassing a range of technologies and strategies, play a pivotal role in achieving these objectives. This abstract provides a concise overview of key aspects of ethylene production control systems, their challenges, and their critical importance. Ethylene production control systems serve as the backbone of modern ethylene plants, orchestrating

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Maheshbhai, Kansara. "Advancements in Cloud Database Migration: Current Innovations and Future Prospects for Scalable and Secure Transitions." Sage Science Review of Applied Machine Learning 7, no. 1 (2024): 127–43. https://doi.org/10.5281/zenodo.15033980.

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<strong>Abstract</strong> Cloud database migration is a seminal transformation in modern data management, constituting the foundation of the evolution from legacy and on-premises environments to scalable and distributed cloud environments. This research paper presents a detailed study of the existing technical challenges and emerging methodologies in cloud database migration with special emphasis on automation, data integrity, and optimization of performance. The study covers advanced migration paradigms that employ state-of-the-art virtualization, container orchestration, and machine learning

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Emmanuel Cadet, Olajide Soji Osundare, Harrison Oke Ekpobimi, Zein Samira, and Yodit Wondaferew Weldegeorgise. "Cloud migration and microservices optimization framework for large-scale enterprises." Open Access Research Journal of Engineering and Technology 7, no. 2 (2024): 046–59. http://dx.doi.org/10.53022/oarjet.2024.7.2.0059.

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As large-scale enterprises increasingly adopt cloud computing, the need for a structured framework to guide seamless cloud migration and optimize microservices architecture becomes critical. This review presents a comprehensive designed to address the challenges and opportunities associated with transitioning to cloud environments and optimizing microservices for performance, scalability, and security. The review begins with an assessment of the enterprise’s current infrastructure, emphasizing a phased approach to cloud migration. It outlines key strategies such as lift-and-shift, re-platformi

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Asfour, Hasan A., Mohammed Z. Allouh, and Raed S. Said. "Myogenic regulatory factors: The orchestrators of myogenesis after 30 years of discovery." Experimental Biology and Medicine 243, no. 2 (2018): 118–28. http://dx.doi.org/10.1177/1535370217749494.

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Prenatal and postnatal myogenesis share many cellular and molecular aspects. Myogenic regulatory factors are basic Helix-Loop-Helix transcription factors that indispensably regulate both processes. These factors (Myf5, MyoD, Myogenin, and MRF4) function as an orchestrating cascade, with some overlapped actions. Prenatally, myogenic regulatory factors are restrictedly expressed in somite-derived myogenic progenitor cells and their derived myoblasts. Postnatally, myogenic regulatory factors are important in regulating the myogenesis process via satellite cells. Many positive and negative regulat

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Mahmud, Shawn A., Jian-Guo Wang, Peng Wei, et al. "The Major Phagocyte Peroxidase-Derived Oxidant, HOSCN (Hypothiocyanous Acid), Induces Proinflammatory and Cytoprotective Gene Expression in Endothelium: A Mechanism for Microlocalized Regulation of Inflammation." Blood 110, no. 11 (2007): 3295. http://dx.doi.org/10.1182/blood.v110.11.3295.3295.

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Abstract Phagocyte peroxidases have recently been shown to play important roles in the pathogenesis of atherosclerosis, inflammatory bowel disease, and asthma. Thiocyanate (SCN-) is the principal physiologic substrate for eosinophil peroxidase (EPO) and a major (i.e., accounting for 50% of H2O2 consumed) substrate for myeloperoxidase (MPO). The product of these reactions is HOSCN (hypothiocyanous acid), a weak, exclusively sulfhydryl-reactive oxidant capable of diffusing across cell membranes to impose intracellular oxidant stress. Endothelium immediately subjacent to or near adherent activate

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Lamprianidou, Eleftheria, Constantinos Tsatalas, Paraskevi Miltiades, et al. "CD4+ T Cells in High-Risk MDS Patients Bear an Aberrant STAT Signaling Biosignature." Blood 124, no. 21 (2014): 1906. http://dx.doi.org/10.1182/blood.v124.21.1906.1906.

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Abstract CD4+ T cells hold a central role in tumor immunity by orchestrating and regulating antitumor responses. Azacytidine can apparently modulate tumor immunity in myelodysplastic syndrome (MDS) patients and affect CD4+ cell polarization, mainly in responding patients. Signal transducer and activator of transcription (STAT) proteins have essential roles in the epigenetic control of T helper (TH) cell differentiation and aberrant STAT signaling is involved in the pathobiology of numerous malignancies by compromising tumor immunity. MDS have a strong immunopathogenetic component, but the CD4+

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Katrašnik, Tomaž, Klemen Zelič, and Igor Mele. "In-Operando Virtual Look inside the Battery: The Role of Physics-Based Models in Advancing State-of-X Diagnostics of Batteries with Phase-Separating Materials." ECS Meeting Abstracts MA2024-02, no. 26 (2024): 2063. https://doi.org/10.1149/ma2024-02262063mtgabs.

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Lithium iron phosphate (LFP)-based batteries, as well as their mixed analogues, such as lithium iron manganese phosphate batteries, are gaining importance owing to their high safety, high power density, acceptable energy density, durability, lack of resource-limiting critical metals, and especially their excellent price-performance ratio. However, these phase-separating active materials are characterized by several intriguing phenomena, as for example inherent voltage hysteresis, when subjected to finite (nearly) constant currents [1], newly reported entering into the voltage hysteresis during

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Mayoral, Arturo, Ricard Vilalta, Raül Muñoz, Ramon Casellas, and Ricardo Martínez. "SDN orchestration architectures and their integration with Cloud Computing Applications." Optical Switching and Networking, February 1, 2016. https://doi.org/10.1016/j.osn.2015.09.007.

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Emerging cloud-based applications, running in geographically distributed data centers (DCs), generate new dynamic traffic patterns which claim for a more efficient management of the traffic flows. Geographically distributed DCs interconnection requires automatic and more dynamic provisioning and deletion of end-to-end (E2E) connectivity services, through heterogeneous network domains. Each network domain may use a different data transport technology but also a different control/management system. The fast development of Software Defined Networking (SDN) and the interworking with current contro

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