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Dissertations / Theses on the topic 'Controlled release technology'

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1

Hussey, Jeremy Steven. "Wood in controlled release technology." Thesis, Bangor University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263193.

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2

Kanga, Yao. "Controlled release of Isothiazoline biocides from industrial minerals." Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/1594/.

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This project investigated how various minerals of different surface areas and morphologies can be used to adsorb isothiazoline biocides for controlled-release and antimicrobial purposes. The absorption of the biocides on the mineral powders was achieved by way of using a bench high shear mill (dry process), or combining them to hydrated minerals (wet process). The characterisation of the minerals was achieved by XRF (chemical composition), XRD (crystal composition), SEM (morphology), B.E.T nitrogen (surface area), and Light Scattering (particle size distribution). HPLC was used to determine th
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Christie, Annette Louise. "Synthesis of biodegradable microparticles for controlled active ingredient release." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/103479/.

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This thesis investigates the degradation and release of a fluorescent dye from biodegradable microparticles. Particular attention is given to determining the effect of polymeric properties on the subsequent microparticle degradation and release rate. Chapter 1 reviews the current polymerisation techniques for the synthesis of polyesters and introduces the synthetic procedures and degradability currently attainable for biodegradable microparticles. The concept of ‘smart’ release technology is introduced and the potential for using biodegradable ‘smart’ particles for enhanced agricultural formul
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Sinha, Piyush Mohan. "Nanoengineered implantable devices for controlled drug delivery." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1115138930.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xxii, 220 p.; also includes graphics (some col.). Includes bibliographical references (p. 202-220). Available online via OhioLINK's ETD Center.
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Syzov, Vladyslav. "Delivery of a coated bioactive from a rumen controlled-release device." The University of Waikato, 2008. http://hdl.handle.net/10289/2368.

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Ruminants possess a unique digestive system. Using the high metabolic potential of the symbiotic microflora of the rumen, ruminants are capable of digesting plant material and obtaining nutrients and energy from this process. Because of the ruminal fermentation, the most bioactives are not stable in the harsh ruminal environment. Therefore there is a need to improve the bioavailability of a bioactive by protecting it from the ruminal digestion. The formulation of protected bioactive can be delivered in the rumen in a controlled manner and over a long period of time. In this project the degree
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Wang, Hongjuan. "Technology of production of drugs with controlled release in capsules based on nanoporous silicon dioxide." Магістерська робота, Київський національний університет технологій та дизайну, 2021. https://er.knutd.edu.ua/handle/123456789/19265.

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The master's thesis is devoted to study the synthesis technology of mesoporous silicon dioxide with solid and hollow structure based on the self-assemble between surfactants, co-structure directing agents and inorganic silica precursors. Well-defined spherical mesoporous silica displays interesting properties for biomedical applications such as uniform particle size, large surface area and tunable pore diameters and volumes, allowing the incorporation of large amounts of drugs and protecting them from deactivation and degradation processes acting as an excellent nanoplatform for drug delivery.
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7

Sui, Cong. "Novel encapsulation of water soluble active ingredients to acheive their controlled release in aqueous environment." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8622/.

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Encapsulation technology has been widely researched and applied to different industry sectors. There are vast examples of encapsulation for controlled release of hydrophilic or hydrophobic ingredients to the target place. However, it is still difficult to encapsulate the small water-soluble salts or molecules, achieving long-term sustained release or even no release in water. Herein, a novel type of organic-inorganic composite solid microsphere, comprised of polystyrene sulfonate and silica was developed here to achieve a sustained release of K+ ions in aqueous environment for over 48 hours. F
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Abu, Awwad Hosam Al-Deen. "Controlled release system for delivery of GET peptide and its application for transcription factor delivery for bone regeneration." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/50996/.

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The repair of bone defects and non-union fractures is a significant challenge for clinicians as it requires tissue replacement. The current graft approaches used to treat these injuries have limitations with regard to quality and availability. This has resulted in research efforts to develop alternative synthetic materials that are able to aid tissue regeneration. These materials usually combined with biological factors to induce cells proliferation and differentiation. Transcription factors can provide specific regulatory effect, however, these transcription factors are very difficult to be d
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9

Dry, Carolyn. "Design of systems for time delayed activated internal release of chemicals in concrete from porous fibers, aggregates of prills, to improve durability /." This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-05222007-091330/.

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Ditto, Andrew. "DNA-LPEI complexes encapsulated in LTP nanospheres as a non-viral gene therapy vector." Akron, OH : University of Akron, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=akron1165596983.

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Thesis (M.S.)--University of Akron, Dept. of Biomedical Engineering, 2006.<br>"December, 2006." Title from electronic thesis title page (viewed 12/31/2008) Advisor, Yang Yun; Committee members, Stephanie Lopina, Steven Schmidt; Department Chair, Daniel Sheffer; Dean of the College, George K. Haritos; Dean of the Graduate School, George R. Newkome. Includes bibliographical references.
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11

Kao, Chen-Yu. "Developing a Minimally Invasive Sustained Release System for Glioma Therapy." Thesis, Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/19757.

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Malignant brain tumor is one of the most lethal forms of cancers. In the United States alone, approximately 20,500 new cases of primary malignant brain and central nervous system tumors are expected to be diagnosed in 2007 with 12,740 deaths estimated. Treatment of malignant brain tumor remains a major challenge despite recent advance in surgery and other adjuvant therapies, such as chemotherapy. The failure of potential effective chemotherapeutics for brain tumor treatment is usually not due to the lack of potency of the drug, but rather can be attributed to lack of therapeutic strategies ca
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Kleinubing, Sirlene Adriana 1980. "Liberação controlada da oxitetraciclina encapsulada em matriz de alginato/quitosana recoberta com Acril-EZE® MP em leito fluidizado." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266562.

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Orientador: Lucia Helena Innocentini Mei<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Química<br>Made available in DSpace on 2018-08-22T20:49:29Z (GMT). No. of bitstreams: 1 Kleinubing_SirleneAdriana_M.pdf: 3412137 bytes, checksum: 4c9018ce01be800e79a8dbd49b20fe27 (MD5) Previous issue date: 2013<br>Resumo: O presente trabalho fundamenta-se no desenvolvimento de micropartículas de polímeros naturais para utilização em sistemas de liberação gastrorresistentes, onde o fármaco passa pelo meio gástrico intacto, permitindo sua absorção apenas no meio entér
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Veiga, Itiara Gonçalves. "Produção e caracterização de membranas de quitosana associada com outros biopolímeros para liberação controlada de anti-inflamatórios." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266664.

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Orientadores: Angela Maria Moraes, Paulo de Tarso Vieira e Rosa, Hermínio Cipriano de Sousa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica<br>Made available in DSpace on 2018-08-21T13:49:40Z (GMT). No. of bitstreams: 1 Veiga_ItiaraGoncalves_D.pdf: 7420007 bytes, checksum: 72fa5c4f048822ac905a8b95278e63f3 (MD5) Previous issue date: 2012<br>Resumo: O corpo humano é recoberto por aproximadamente 2 m2 de pele, e lesões cutâneas, além de causarem danos físicos, mecânicos e térmicos, podem também afetar as funções fisiológicas de outros tecidos, gerando de
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Correa, Renata Mukai. "Preparo e caracterização de microcapsulas obtidas por polimerização ionica para alimentação de larvas de peixe." [s.n.], 2003. http://repositorio.unicamp.br/jspui/handle/REPOSIP/255987.

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Orientador: Carlos Raimundo Ferreira Grosso<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos<br>Made available in DSpace on 2018-08-03T18:23:17Z (GMT). No. of bitstreams: 1 Correa_RenataMukai_M.pdf: 13500100 bytes, checksum: 565403535c4481aa54c2bbd82994ce84 (MD5) Previous issue date: 2003<br>Resumo: Este trabalho visou a produção de microcápsulas capazes de reter proteínas, para serem utilizadas na tentativa de substituição dos organismos vivos usados na alimentação de larvas de peixes. Quatro diferentes polissacarídeos: alginato, carragena,
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15

Dry, Carolyn Minnetta. "Design of systems for time delayed activated internal release of chemicals in concrete from porous fibers, aggregates of prills, to improve durability." Diss., Virginia Tech, 1991. http://hdl.handle.net/10919/37870.

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Incorporation of chemicals into the internal matrix of cement or concrete, with later release occurring upon stimulation, alters the matrix parameters from those at the initial set. Permeability is reduced, for example, and therefore durability enhanced. The advantages of these designs would be the ability to reduce maintenance and repair costs in the initial building configuration and to delay the time of eventual repair. The components and the structure could take greater environmental abuse also. Permeability is significantly reduced by release of a polymer from wax-coated porous fibers
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Kubo, Tatiana Miyuki Ogawa. "Preparação e caracterização de microparticulas de hialuronato de sodio para encapsulação e liberação controlada de proteinas para aplicação nasal." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/267236.

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Orientador: Maria Helena Andrade Santana<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica<br>Made available in DSpace on 2018-08-04T23:14:50Z (GMT). No. of bitstreams: 1 Kubo_TatianaMiyukiOgawa_M.pdf: 3390196 bytes, checksum: 90fbf573dfcb12a87da26f2fdcbfb4dd (MD5) Previous issue date: 2005<br>Resumo: Neste trabalho foi feito o estudo da preparação de microesferas de hialuronato de sódio pelo método de emulsificação e evaporação de solvente, utilizando temperatura como agente de retificação física. O assunto foi abordado com ênfase na influência d
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Grillo, Renato 1984. "Desenvolvimento de sistemas de liberação modificada para herbicidas triazínicos utilizando nanocápsulas poliméricas." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314420.

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Orientador: Leonardo Fernandes Fraceto<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-19T01:41:13Z (GMT). No. of bitstreams: 1 Grillo_Renato_M.pdf: 3217546 bytes, checksum: e0e0715313f026b21d8edb4e55fd94cf (MD5) Previous issue date: 2011<br>Resumo: Muitas das novas tecnologias desenvolvidas atualmente envolvem a nanobiotecnologia, dentre elas, os sistemas carreadores nanoestruturados poliméricos. Os sistemas nanoestruturados poliméricos (SNP) agem como compartimentos transportadores de substâncias bioativas e aprese
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18

Corrêa, Daniel Henrique do Amaral. "Citotoxicidade da desidrocrotonina livre e veiculada em sistemas de liberação controlada : nanoesferas de acido poli-lactico-co-glicolico (PLGA) e complexos de inclusão com ciclodextrinas." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314607.

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Orientador: Patricia da Silva Melo<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-05T14:49:01Z (GMT). No. of bitstreams: 1 Correa_DanielHenriquedoAmaral_M.pdf: 1457648 bytes, checksum: 6adbe0feca89d1798ac2084d68454c69 (MD5) Previous issue date: 2005<br>Resumo: A droga desidrocrotonina (DHC), isolada da planta Croton cajucara, é conhecida pelas suas atividades biológicas, entretanto apresenta uma vasta e conhecida toxicidade. Neste trabalho foram preparadas formulações contendo DHC associada a polímeros (PLGA) ou cic
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19

Souza, Renata Francielle Bombaldi de 1989. "Membranas de quitosana complexada com alginato e xantana : comportamento na presença de diferentes proporções de água e incorporação de eritromicina." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266113.

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Orientador: Ângela Maria Moraes<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Química<br>Made available in DSpace on 2018-08-25T00:10:27Z (GMT). No. of bitstreams: 1 Souza_RenataFrancielleBombaldide_M.pdf: 3223063 bytes, checksum: 499816d787b51fb2d1c646cab724d531 (MD5) Previous issue date: 2014<br>Resumo: A quitosana, o alginato e a xantana são polímeros naturais biodegradáveis e biocompatíveis muito utilizados na obtenção de curativos para tratamento de lesões de pele. Compostos ativos podem ser adicionados a dispositivos formados pela combinação des
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Sacchetin, Priscila Soares Costa. "Produção de micropartículas poliméricas por tecnologia de fluidos supercríticos para aplicação como veículo na administração oral de 17'alfa'-metiltestosterona para tilápias do Nilo." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266610.

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Orientadores: Ângela Maria Moraes, Paulo de Tarso Vieira e Rosa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Química<br>Made available in DSpace on 2018-08-21T17:27:21Z (GMT). No. of bitstreams: 1 Sacchetin_PriscilaSoaresCosta_D.pdf: 18116107 bytes, checksum: a46dd208ddd43d66ee2bb2d29e98cc46 (MD5) Previous issue date: 2012<br>Resumo: No presente trabalho propôs-se a formação de carreadores orais compostos pelos polímeros sintéticos PLA (poli(L-ácido lático)), PLGA (poli(50/50 DL-ácido lático-co-glicólico)) e PCL (policaprolactona) para a construção de sist
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Souza, Fernanda Carla Bombaldi de 1989. "Incorporação de alfa-bisabolol em membranas de policaprolactona e de quitosana complexada com goma guar." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266114.

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Orientador: Ângela Maria Moraes<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Agrícola<br>Made available in DSpace on 2018-08-25T01:12:46Z (GMT). No. of bitstreams: 1 Souza_FernandaCarlaBombaldide_M.pdf: 2498035 bytes, checksum: f26cf0a46c0249d60c3316fd94c93e91 (MD5) Previous issue date: 2014<br>Resumo: A quitosana, a goma guar e a policaprolactona são exemplos de polímeros muito usados na obtenção de curativos para a terapia de lesões de pele devido ao fato de serem biocompatíveis e biodegradáveis. A fim de aumentar a atividade biológica destes curat
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Bernatavicius, Sergio Tadeu. "Utilização de microesferas de poli (L-acido-latico) contendo medicamento no tratamento de perda do tecido dental." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263896.

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Orientador : Eliana Aparecida de Rezende Duek<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecanica<br>Made available in DSpace on 2018-08-04T01:54:38Z (GMT). No. of bitstreams: 1 Bernatavicius_SergioTadeu_M.pdf: 9386061 bytes, checksum: 9e736c52e1042de3187574f10e183c68 (MD5) Previous issue date: 2004<br>Resumo: Um dos pontos que deve ser considerado de difícil solução no Brasil, é a perda dentinária. Vários materiais tem sido estudados para minimizar o problema, mas nenhum atende às necessidades de tal aplicação. Nesse sentido, o objetivo do present
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23

Prata, Ana Silvia 1977. "Estudo dos parametros fisico-quimicos envolvidos na formação de microcapsulas produzidas por coacervação complexa." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/255965.

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Orientadores: Carlos Raimundo Ferreira Grosso, Maria Ines Re<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos<br>Made available in DSpace on 2018-08-06T03:05:42Z (GMT). No. of bitstreams: 1 Prata_AnaSilvia_D.pdf: 8487208 bytes, checksum: c134b0c8ddb26e852727eca6b6bef640 (MD5) Previous issue date: 2006<br>Resumo: Microencapsulação é uma tecnologia usada como ferramenta potencial para proteção de um composto e modulação de sua liberação. Atualmente, estudos na área de micropartículas e liberação controlada estão bastante avançados e uma variedade de
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Meslard, Jean-Claude. "Immobilisation temporaire de medicaments par des liaisons hydrolysables sur des polymeres biocompatibles : application a l'ophtalmologie." Paris 6, 1988. http://www.theses.fr/1988PA066417.

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L'objectif est l'immobilisation reversible de medicaments (chloramphenicol, indometacine) au sein de lentilles de contact hydrophiles permettant une liberation lente et continue lors de leur adaptation sur des yeux malades
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Freitas, Miller Nunes de. "Desenvolvimento, caracterização e avaliação de um sistema osmótico do tipo bicamada." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-27022009-170513/.

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Os comprimidos osmóticos do tipo bicamada ou \"push pull\" são sistemas reservatórios constituídos de um núcleo bicamada, circundado por uma membrana semipermeável e com um orifício de liberação perfurado a laser que permitem a liberação do fármaco através da cinética de ordem zero. Este sistema possui a vantagem de apresentar uma liberação controlada e não influenciada pelos fatores fisiológicos do trato gastrointestinal, permitindo aplicações terapêuticas para novos fármacos e inclusive para fármacos já existentes. O presente projeto contemplou as etapas de desenvolvimento, caracterização e
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Bakhouya, Abderrahmane. "Etude du processus de libération des principes actifs à partir de formes galéniques lipidiques à matrice de gélucire : modélisation de la pénétration tissulaire de la ciprofloxacine." Saint-Etienne, 1996. http://www.theses.fr/1996STET4013.

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Les formes galéniques matricielles, à matrice lipidique tels que les gélucires, permettent une libération contrôlée du principe actif. Ces matrices peuvent subir une érosion plus ou moins prononcée selon la nature de l'excipient. Lorsque le gélucire est hydrophile, le processus de libération s'effectue par érosion de la forme galénique. Avec un gélucire lipophile, le processus de libération est contrôlé par diffusion. Pour simuler le contrôle de la libération par érosion dans l'organisme, nous avons construit un modèle numérique qui tient compte de tous les facteurs ; notamment, les trois stad
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Levet, Vincent. "Development and Evaluation of Controlled-Release Cisplatin Dry Powders for Inhalation against Lung Tumours." Doctoral thesis, Universite Libre de Bruxelles, 2017. https://dipot.ulb.ac.be/dspace/bitstream/2013/249264/4/TOC.pdf.

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Lung cancer is the deadliest cancer in the world, with a global 5-year survival rate of about 15%. Despite a notable impact of the latest improvements in prevention, screening, detection and staging, the efficacy of conventional treatments is not sufficient and has reached a therapeutic plateau. These conventional treatments involve a combination of surgery, radiotherapy (RT) and chemotherapy (CT). CT is used in almost all stages: in operable and inoperable stages to limit tumour cell invasion and in latest stages as a palliative treatment. Cisplatin is one of the most frequently used and most
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Zhu, Xuntao. "Development of target release rate concept for controlled release packaging." 2008. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051770.

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Lang, Jillian C. "Tocopherol stability in controlled release packaging films." 2009. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051028.

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CHEN, FU-RONG, and 陳福榮. "A study for controlled release microcapsules using ion exchange technology." Thesis, 1986. http://ndltd.ncl.edu.tw/handle/00301235845828517953.

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Coelho, Catarina Cardoso. "Heparinized nanohydroxyapatite/collagen granules for controlled release of vancomycin." Dissertação, 2013. https://repositorio-aberto.up.pt/handle/10216/90326.

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Coelho, Catarina Cardoso. "Heparinized nanohydroxyapatite/collagen granules for controlled release of vancomycin." Master's thesis, 2013. https://repositorio-aberto.up.pt/handle/10216/90326.

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Araújo, Joana Catarina Ribeiro. "Biphasic Controlled Release of Active Pharmaceutical Ingredients from Biodegradable Implants." Dissertação, 2014. https://repositorio-aberto.up.pt/handle/10216/88457.

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Araújo, Joana Catarina Ribeiro. "Biphasic Controlled Release of Active Pharmaceutical Ingredients from Biodegradable Implants." Master's thesis, 2014. https://repositorio-aberto.up.pt/handle/10216/88457.

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Ching-yao, Yang, and 楊景堯. "The Study of Microencapsulation Technology on the Preparation of Controlled Release Microcapsules of Drugs." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/47199191829834188319.

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博士<br>國立成功大學<br>化學工程學系<br>88<br>Microencapsulation of aspirin in ethylcellulose was demonstrated using an coacervation phase separation technique. First, using an oil-in-water emulsion non-solvent addition method to prepare microcapsules. The ethylcellulose viscosity and drug to ethylcellulose ratio have very significant effect (significance level 1%) to the recovered weight of microcapsules from analysis of variance(ANOVA). The appropriate viscosity of ethylcellulose and higher drug to ethylcellulose ratio increase the recovered weight. The agitation speed and drug to ethylcellulose ratio hav
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Leung, Sau-Hung Spence. "Polymer structural features contributing to mucoadhesion." 1987. http://catalog.hathitrust.org/api/volumes/oclc/17926556.html.

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Thesis (Ph. D.)--University of Wisconsin--Madison, 1987.<br>Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 159-183).
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"Development of a sustained-release microsphere formulation for delicate therapeutic proteins using a novel aqueous-aqueous emulsion technology." 2008. http://library.cuhk.edu.hk/record=b5896772.

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Zhang, Xinran.<br>Thesis submitted in: December 2007.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.<br>Includes bibliographical references (leaves 80-87).<br>Abstracts in English and Chinese.<br>TITLE PAGE --- p.i<br>ABSTRACT --- p.ii<br>中文摘要 --- p.v<br>ACKNOWLEDGEMENTS --- p.vii<br>TABLE OF CONTENTS --- p.viii<br>LIST OF FIGURES --- p.xi<br>LIST OF TABLES --- p.xiv<br>ABBREVIATIONS --- p.xv<br>Chapter CHAPTER 1. --- Introduction<br>Chapter 1.1. --- Rationale of the Study --- p.1<br>Chapter 1.2. --- Current technologies for formulating long-acting parenteral protein deli
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