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Journal articles on the topic 'Copper and iron'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Chen, Teng-Chien, Ricky Priambodo, Ruo-Lin Huang, and Yao-Hui Huang. "The Effective Electrolytic Recovery of Dilute Copper from Industrial Wastewater." Journal of Waste Management 2013 (April 9, 2013): 1–6. http://dx.doi.org/10.1155/2013/164780.

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Electroplating copper industry was discharged huge amount wastewater and cause serious environmental and health damage in Taiwan. This research applied electrical copper recovery system to recover copper metal. In this work, electrotreatment of a industrial copper wastewater ([Cu] = 30000 mg L−1) was studied with titanium net coated with a thin layer of RuO2/IrO2 (DSA) reactor. The optimal result for simulated copper solution was 99.9% copper recovery efficiency in current density 0.585 A/dm2 and no iron ion. Due to high concentration of iron and chloride ions in real industrial wastewater, th

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2

Lee, Jennifer K., Jung-Heun Ha, and James F. Collins. "Dietary Iron Intake in Excess of Requirements Impairs Intestinal Copper Absorption in Sprague Dawley Rat Dams, Causing Copper Deficiency in Suckling Pups." Biomedicines 9, no. 4 (2021): 338. http://dx.doi.org/10.3390/biomedicines9040338.

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Physiologically relevant iron-copper interactions have been frequently documented. For example, excess enteral iron inhibits copper absorption in laboratory rodents and humans. Whether this also occurs during pregnancy and lactation, when iron supplementation is frequently recommended, is, however, unknown. Here, the hypothesis that high dietary iron will perturb copper homeostasis in pregnant and lactating dams and their pups was tested. We utilized a rat model of iron-deficiency/iron supplementation during pregnancy and lactation to assess this possibility. Rat dams were fed low-iron diets e

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3

Doguer, Caglar, Jung‐Heun Ha, and James F. Collins. "Intersection of Iron and Copper Metabolism in the Mammalian Intestine and Liver." Comprehensive Physiology 8, no. 4 (2018): 1433–61. https://doi.org/10.1002/j.2040-4603.2018.tb00047.x.

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ABSTRACTIron and copper have similar physiochemical properties; thus, physiologically relevant interactions seem likely. Indeed, points of intersection between these two essential trace minerals have been recognized for many decades, but mechanistic details have been lacking. Investigations in recent years have revealed that copper may positively influence iron homeostasis, and also that iron may antagonize copper metabolism. For example, when body iron stores are low, copper is apparently redistributed to tissues important for regulating iron balance, including enterocytes of upper small bowe

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4

Rajiv Gaikwad Chitra, Ranjana. "Copper and Iron Levels in Wilson's Disease Cases." International Journal of Science and Research (IJSR) 13, no. 3 (2024): 795–96. http://dx.doi.org/10.21275/sr24311102611.

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5

Jiang, Long Kui. "Influence on Concentration of Magnetite with Changing of Fe³⁺/Fe²⁺ in Copper Slag." Advanced Materials Research 634-638 (January 2013): 3080–83. http://dx.doi.org/10.4028/www.scientific.net/amr.634-638.3080.

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Large number of available resource is in the copper slag, which includes oxides of copper and oxides of iron. The total iron in copper slag is usually above 35%, and iron element in copper slag are mainly distributed in olivine phase and magnetic iron oxide minerals. Because minerals in copper slag embedded with each other and the grain of minerals in copper slag are very small, so it is very difficult to recover iron from the copper slag by means of traditional separation technology. Based on the characteristics of copper slag, iron in copper slag can selectively be gathered to magnetite phas

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6

Chillappagari, Shashi, Andreas Seubert, Hein Trip, Oscar P. Kuipers, Mohamed A. Marahiel, and Marcus Miethke. "Copper Stress Affects Iron Homeostasis by Destabilizing Iron-Sulfur Cluster Formation in Bacillus subtilis." Journal of Bacteriology 192, no. 10 (2010): 2512–24. http://dx.doi.org/10.1128/jb.00058-10.

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ABSTRACT Copper and iron are essential elements for cellular growth. Although bacteria have to overcome limitations of these metals by affine and selective uptake, excessive amounts of both metals are toxic for the cells. Here we investigated the influences of copper stress on iron homeostasis in Bacillus subtilis, and we present evidence that copper excess leads to imbalances of intracellular iron metabolism by disturbing assembly of iron-sulfur cofactors. Connections between copper and iron homeostasis were initially observed in microarray studies showing upregulation of Fur-dependent genes

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7

Takasugi, Satoshi, Tohru Matsui, and Hideo Yano. "Iron supplementation by intraperitoneal injection eliminates the accumulation of hepatic copper induced by excess calcium in rats." British Journal of Nutrition 102, no. 2 (2009): 258–63. http://dx.doi.org/10.1017/s0007114508184707.

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Excess calcium is well known to induce iron deficiency. Furthermore, excess calcium increases hepatic copper concentration and decreases renal copper concentration. We investigated the effect of iron supplementation on the tissue distribution of copper in rats given a high-calcium diet. Male rats (5 weeks old) were divided into four groups; a control group, and three groups given a diet containing 5-fold higher calcium than its requirement and an intraperitoneal iron supplementation of 0, 1 or 2 mg/week as iron dextran. The animals were fed their respective experimental diets with or without i

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8

van Bakel, Harm, Eric Strengman, Cisca Wijmenga, and Frank C. P. Holstege. "Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism." Physiological Genomics 22, no. 3 (2005): 356–67. http://dx.doi.org/10.1152/physiolgenomics.00055.2005.

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Exhaustive microarray time course analyses of Saccharomyces cerevisiae during copper starvation and copper excess reveal new aspects of metal-induced gene regulation. Aside from identifying targets of established copper- and iron-responsive transcription factors, we find that genes encoding mitochondrial proteins are downregulated and that copper-independent iron transport genes are preferentially upregulated, both during prolonged copper deprivation. The experiments also suggest the presence of a small regulatory iron pool that links copper and iron responses. One hundred twenty-eight genes w

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9

Ranganathan, Perungavur N., Yan Lu, Lingli Jiang, Changae Kim, and James F. Collins. "Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake." Blood 118, no. 11 (2011): 3146–53. http://dx.doi.org/10.1182/blood-2011-05-352112.

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AbstractIncreases in serum and liver copper content are noted during iron deficiency in mammals, suggesting that copper-dependent processes participate during iron deprivation. One point of intersection between the 2 metals is the liver-derived, multicopper ferroxidase ceruloplasmin (Cp) that is important for iron release from certain tissues. The current study sought to explore Cp expression and activity during physiologic states in which hepatic copper loading occurs (eg, iron deficiency). Weanling rats were fed control or low iron diets containing low, normal, or high copper for ∼ 5 weeks,

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10

Ha, Jung-Heun, Caglar Doguer, and James F. Collins. "Consumption of a high-iron diet disrupts homeostatic regulation of intestinal copper absorption in adolescent mice." American Journal of Physiology-Gastrointestinal and Liver Physiology 313, no. 4 (2017): G353—G360. http://dx.doi.org/10.1152/ajpgi.00169.2017.

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High-iron feeding of rodents has been commonly used to model human iron-overload disorders. We recently noted that high-iron consumption impaired growth and caused severe systemic copper deficiency in growing rats, but the mechanism by which this occurred could not be determined due to technical limitations. In the current investigation, we thus utilized mice; first to determine if the same phenomenon occurred in another mammalian species, and second since we could assess in vivo copper absorption in mice. We hypothesized that excessive dietary iron impaired intestinal copper absorption. Weanl

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11

Thomas, Carla, and Phillip S. Oates. "Copper deficiency increases iron absorption in the rat." American Journal of Physiology-Gastrointestinal and Liver Physiology 285, no. 5 (2003): G789—G795. http://dx.doi.org/10.1152/ajpgi.00509.2002.

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Release of iron from enterocytes and hepatocytes is thought to require the copper-dependent ferroxidase activity of hephaestin (Hp) and ceruloplasmin (Cp), respectively. In swine, copper deficiency (CD) impairs iron absorption, but whether this occurs in rats is unclear. By feeding a diet deficient in copper, CD was produced, as evidenced by the loss of copper-dependent plasma ferroxidase I activity, and in enterocytes, CD reduced copper levels and copper-dependent oxidase activity. Hematocrit was reduced, and liver iron was doubled. CD reduced duodenal mucosal iron and ferritin, whereas CD in

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12

Han, Okhee, and Marianne Wessling-Resnick. "Copper repletion enhances apical iron uptake and transepithelial iron transport by Caco-2 cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 282, no. 3 (2002): G527—G533. http://dx.doi.org/10.1152/ajpgi.00414.2001.

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The influence of copper status on Caco-2 cell apical iron uptake and transepithelial transport was examined. Cells grown for 7–8 days in media supplemented with 1 μM CuCl2had 10-fold higher cellular levels of copper compared with control. Copper supplementation did not affect the integrity of differentiated Caco-2 cell monolayers grown on microporous membranes. Copper-repleted cells displayed increased uptake of iron as well as increased transport of iron across the cell monolayer. Northern blot analysis revealed that expression of the apical iron transporter divalent metal transporter-1 (DMT1

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13

Arredondo, Miguel, Patricia Muñoz, Casilda V. Mura, and Marco T. Núñez. "DMT1, a physiologically relevant apical Cu1+transporter of intestinal cells." American Journal of Physiology-Cell Physiology 284, no. 6 (2003): C1525—C1530. http://dx.doi.org/10.1152/ajpcell.00480.2002.

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Despite important advances in the understanding of copper secretion and excretion, the molecular components of intestinal copper absorption remain a mystery. DMT1, also known as Nramp2 and DCT1, is the transporter responsible for intestinal iron uptake. Electrophysiological evidence suggests that DMT1 can also be a copper transporter. Thus we examined the potential role of DMT1 as a copper transporter in intestinal Caco-2 cells. Treatment of cells with a DMT1 antisense oligonucleotide resulted in 80 and 48% inhibition of iron and copper uptake, respectively. Cells incorporated considerable amo

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14

Park, Yong-Sung, Suzie Kang, Hyewon Seo, and Cheol-Won Yun. "A copper transcription factor, AfMac1, regulates both iron and copper homeostasis in the opportunistic fungal pathogen Aspergillus fumigatus." Biochemical Journal 475, no. 17 (2018): 2831–45. http://dx.doi.org/10.1042/bcj20180399.

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Although iron and copper are co-ordinately regulated in living cells, the homeostatic effects of each of these metals on the other remain unknown. Here, we show the function of AfMac1, a transcriptional activator of the copper and iron regulons of Aspergillus fumigatus, on the interaction between iron and copper. In addition to the copper-specific AfMac1-binding motif 5′-TGTGCTCA-3′ found in the promoter region of ctrC, the iron-specific AfMac1-binding motif 5′-AT(C/G)NN(A/T)T(A/C)-3′ was identified in the iron regulon but not in the copper regulon by ChIP sequence analysis. Furthermore, mutat

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15

AGUNBIADE, J. A., and G. M. BABATUNDE. "COPPER AND IRON SUPPLEMENTATION IN THE TROPICAL ENVIRONMENT EFFECTS ON HAEMATOLOGICAL MEASUREMENTS, ORGAN WEIGHTS, TISSUE COPPER AND IRON." Nigerian Journal of Animal Production 22, no. 1 (2021): 49–55. http://dx.doi.org/10.51791/njap.v22i1.2028.

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The study which lasted 3 months was a factorial arrangement in which nine dietary treatments resulting from supplementation of a commercial layers diet with 0, 200 or 400 mg/kg Copper and 0, 100 or 200 mg/kg Iron were fed to 135 fifty two-week old laying hens of the Golden Hubbard Connect Strain. After 12 weeks on the diets, three birds, randomly selected from each treatment, were slaughtered and their blood, liver, spleen and heart analysed for effect of supplementary copper and iron on haemoglobin content, packed cell volume and weights of the liver, spleen and heart and their copper and iro

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16

Kim, Youn Che, and Myung Jin Suk. "Expansion Behavior of Iron-Copper Compact from (FeCu) Pre-Alloyed Powder." Materials Science Forum 534-536 (January 2007): 517–20. http://dx.doi.org/10.4028/www.scientific.net/msf.534-536.517.

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Dilatometric curves of iron-copper compact made from elemental or pre-alloyed powder were compared in order to study its expansion mechanism. The compacts from a mixture of elemental iron and copper powders showed the maximum expansion at the copper powder content of 7.44mass% and at the sintering temperatures above the copper melting-point. In the case of the compacts from a mixture of iron pre-alloyed powder of (Fe- 3.44mass%Cu) and copper powder, the maximum expansion which is lower than the former case was obtained at the additive copper powder content of 4.00mass%. But the compact from a

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17

Qu, Yi, Keqin Tan, Baojun Zhao, and Sui Xie. "Recovery of Cu-Fe Alloy from Copper Smelting Slag." Metals 13, no. 2 (2023): 271. http://dx.doi.org/10.3390/met13020271.

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Copper smelting slag usually contains 1–6 wt% copper, which can be recovered by pyrometallurgical and flotation processes. However, the tailing slags still consist of 0.3–0.7 wt% Cu and 35–45 wt% Fe equivalents to those in the copper and iron ores, respectively. Most of the research was focused on the recovery of iron from the tailing slags. Copper can increase the mechanical strength, corrosion resistance and antibacterial property of some steels. A new process to recover copper and iron directly and fully from hot copper smelting slag is proposed to produce Cu-Fe alloy for steel production.

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18

Chen, Lu, Qi Gong, Xiao Ling Wei, and Qian Hou. "Analysis of Iron in Copper, Copper Oxide and Copper Nitrate by Solid-Phase Extraction ICP-AES Method." Advanced Materials Research 396-398 (November 2011): 238–40. http://dx.doi.org/10.4028/www.scientific.net/amr.396-398.238.

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The reasearch shows that when the mass ratio of copper to iron is equal or greater than 100, the influence of copper on the determination of trace iron can not be ignored. To eliminate the interference, the polypropylene radical strong base anion ion exchange fiber was taken as the solid phase extraction solvent. Extraction and separation of trace iron (Ⅲ) from solution copper (Ⅱ) by the extraction solvent was studied. The extraction conditions including of adsorption and elution were optimized. The strong base anion ion exchange fiber was put into the analysis solution with the medium of 6mol

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19

Wang, Jei Pil. "Development of the Process of Manufacturing Pig Iron for Cast Iron from Copper Slag." Applied Mechanics and Materials 711 (December 2014): 218–21. http://dx.doi.org/10.4028/www.scientific.net/amm.711.218.

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A study on the manufacturing pig iron for cast iron from copper slag has been conducted to recover iron-copper matte to be used as a raw material for foundry industries. The copper slag was reduced by carbothermic reaction at 1300°C for 2 hours using electric furnace. Finally, iron-copper matte was successfully obtained with about 93 wt.% and 5 wt.%, respectively.

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20

Hasegawa,, M., K. Wakimoto,, and M. Iwase,. "Activities of Iron in Liquid Copper-Iron Alloys Saturated with Copper-Iron Solid Solutions." High Temperature Materials and Processes 21, no. 5 (2002): 243–50. http://dx.doi.org/10.1515/htmp.2002.21.5.243.

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21

Al-Shukry, Abbas H., Zain E. Mansor, and Nada A. Abd Al Hussein Al -Hussein. "Simultaneous Determination of Iron and Copper in Aqueous Solution Using Spectrophotometry." Journal Port Science Research 7, no. 1 (2024): 15–21. http://dx.doi.org/10.36371/port.2024.1.3.

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Iron and copper mixtures were quantitatively determined in aqueous solutions for the first time using the analytical method in this approach with the aid of T60U Spectrophotometer. The method is so simple, fast, economic, and can be carried out easily on a bench. The absorbencies for iron, copper and iron-copper mixtures in aqueous solution were measured using T60U adopted with UVWin6 software UV -VIS Spectrometer (pg instruments United Kingdom) by filling two 5 ml quartz cells of dimensions 1*1*5 cm, the first is filled with the blank solution which is a solution containing all the constituen

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22

Hussein, Al, Marah Hameed, Waleed Jalil, and Ali Ezzy. "<b>Evaluation of factors affecting the physiological levels of copper and iron in sheep and cattle in some areas of Diyala Governorate, Iraq</b>." Open Veterinary Journal 15, no. 1 (2025): 261. https://doi.org/10.5455/ovj.2025.v15.i1.24.

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Background: Trace minerals are important components of many physiological functions, including growth, development, and the immune response. Aim: Evaluation of copper and iron status in sheep and cattle in some areas of Diyala governorate, Iraq. Methods: One hundred blood samples were collected, 50 from sheep and 50 from cattle in order to measure the levels of copper and iron in the serum. Results: In sheep, serum level of copper significantly increased among females in comparison to males, while among cattle, serum level of copper significantly decreased in females in in comparison with male

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23

Babaei, S., and N. Khakipour. "Assessment of Heavy Metals Concentrations in Roadside Canola Fields in Mazandaran Province, Iran." Journal of Applied Sciences and Environmental Management 24, no. 9 (2020): 1617–23. http://dx.doi.org/10.4314/jasem.v24i9.20.

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Contamination of agricultural products with heavy metals in soil and air is considered as serious threat to the quality and safety of these products. Cars and vehicles are among the major sources of heavy metals such as lead, iron and copper in the environment surrounding roads and highways. According to carcinogenic and destructive effects of these elements on human health, the aim of this study is to measure the concentrations of lead, iron and copper resulting from the traffic of vehicles available in the soil and canola plants growing in the central regions of MAZANDARAN province in Iran.

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24

Manger, Priyanka Thapa, Gyanendra Kumar Yadav, Dhananjay Tiwari, Richa Awasthi, and Durga Prasad Verma. "Serum Copper, Iron, and Total Iron Binding Capacity in Hypothyroidism: A Case Control Study." Molecular and Cellular Biomedical Sciences 7, no. 3 (2023): 141. http://dx.doi.org/10.21705/mcbs.v7i3.336.

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Background: Thyroid hormone metabolism is linked to iron metabolism. Thyroperoxidase, a key enzyme in the biosynthesis of thyroid hormones, is iron-dependent. Thus, iron deficiency might be the primary cause of hypothyroidism. Copper is another trace element that has been linked to thyroid status. Copper regulates excessive thyroxine (T4) absorption and reduces cell damage during thyroid hormone synthesis. The present study clarified the possible correlations between iron and copper levels as well as total iron binding capacity (TIBC) and triiodothyronine (T3), T4, as well as thyroid-stimulati

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Rajendra, Prasad, P. Thankachan P., T. Thomas Molly, and Pathak Rajiv. "Synthesis of aryl substituted azomethine complexes of iron-, cobalt- and copper(II)." Journal of Indian Chemical Society Vol. 78, Jan 2001 (2001): 28–31. https://doi.org/10.5281/zenodo.5849469.

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Department of Chemistry, University of Roorkee, Roorkee-247 667, India <em>E-mail</em> : rajenfcy @rurkiu.ernet.in School of Studies in Chemistry, Vikram University, Ujjain-456 010, India <em>Manuscript received  March 2000, revised 6 July 2000, accepted 26 August 2000</em> Pseudotetrahedral and pseudooctahedral complexes of the types [ML<sub>2</sub>Cl<sub>2</sub>], [M(L-L)Cl<sub>2</sub>], [ML<sub>4</sub>Cl<sub>2</sub>] and [M(L-L)CI<sub>2</sub>]  (where, L = C<sub>6</sub>H<sub>5</sub>CH=NC<sub>6</sub>H<sub>5</sub> OR C<sub>6</sub>H<sub>5</sub>CH=NC<sub>6</su

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Day, Patrick Lloyd, Ria Fyffe-Freil, Patrick Vanderboom, et al. "Iron and Copper Liver Concentrations in Wilson Disease." Journal of Gastrointestinal and Liver Diseases 33, no. 4 (2024): 517–23. https://doi.org/10.15403/jgld-5662.

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Background and Aims: Wilson disease (WD) results in the defective incorporation of copper into ceruloplasmin as well as decreased biliary copper excretion. Secondary iron overload has also been associated with WD; however, the prevalence is currently unknown. This study aims to determine the prevalence of potential secondary iron overload in patients suspected to have WD. The secondary aim was to determine whether common laboratory tests were associated with liver copper concentrations or the need for liver transplantation in a subset of patients with confirmed WD. Methods: Using our instituti

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27

La Fontaine, Sharon, Jeanette M. Quinn, Stacie S. Nakamoto, et al. "Copper-Dependent Iron Assimilation Pathway in the Model Photosynthetic Eukaryote Chlamydomonas reinhardtii." Eukaryotic Cell 1, no. 5 (2002): 736–57. http://dx.doi.org/10.1128/ec.1.5.736-757.2002.

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ABSTRACT The unicellular green alga Chlamydomonas reinhardtii is a valuable model for studying metal metabolism in a photosynthetic background. A search of the Chlamydomonas expressed sequence tag database led to the identification of several components that form a copper-dependent iron assimilation pathway related to the high-affinity iron uptake pathway defined originally for Saccharomyces cerevisiae. They include a multicopper ferroxidase (encoded by Fox1), an iron permease (encoded by Ftr1), a copper chaperone (encoded by Atx1), and a copper-transporting ATPase. A cDNA, Fer1, encoding ferr

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28

Li, Zhongkai, Chunming Liu, and Yujie Liu. "Dislocation hardening coupling between hard matrix and soft zones in a dual-phase heterostructured material." Journal of Physics: Conference Series 2459, no. 1 (2023): 012029. http://dx.doi.org/10.1088/1742-6596/2459/1/012029.

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Abstract Strain hardening coupling between hard and soft zones is still not well understood in heterostructured materials. Here we report the coupling of dislocation hardening between hard iron matrix and soft copper zones in heterostructured Fe-40Cu dual-phase materials. Dislocation hardening is the predominant hardening mechanism in the Fe-40Cu materials, as dislocations dominate plastic deformation in both iron and copper. Low-temperature annealing kept highly deformed iron matrix strong and inductile but softened copper zones by promoting recrystallization in them. This raised plastic inco

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29

Severin, Thorsten, Thilo Rehren, and Helmut Schleicher. "Early metal smelting in Aksum, Ethiopia: copper or iron?" European Journal of Mineralogy 23, no. 6 (2011): 981–92. http://dx.doi.org/10.1127/0935-1221/2011/0023-2167.

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30

Chekman, I. S. "Pharmacological Properties of Metal (Silver, Copper, and Iron) Nanoparticles." Science and innovation 11, no. 1 (2015): 67–71. http://dx.doi.org/10.15407/scine11.01.067.

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Myrzaliev, B. M., Kulgamal A. Nogaeva, and E. B. Kolmachikhina. "The Metallurgical Characterization of Iron-Containing Concentrate." Materials Science Forum 989 (May 2020): 428–33. http://dx.doi.org/10.4028/www.scientific.net/msf.989.428.

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The expediency of processing iron-containing concentrate with low iron content, increased content of manganese and copper is considered in the article. To process such a concentrate, a metallization process is proposed to produce sponge iron with a reducing agent - carbon. It was found that in solid-phase reduction at 1150 °C iron is reduced to a greater extent, as well as small particles with a copper content of about 95%, manganese is not recovered. The simulation process of metallization with carbon at a temperature of 1250 °C shows that iron is mainly distributed in the metallic phase, to

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Xie, Liwei, and James F. Collins. "Copper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cells." American Journal of Physiology-Cell Physiology 304, no. 3 (2013): C257—C262. http://dx.doi.org/10.1152/ajpcell.00336.2012.

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Iron deficiency decreases oxygen tension in the intestinal mucosa, leading to stabilization of hypoxia-inducible transcription factor 2α (Hif2α) and subsequent upregulation of genes involved in iron transport [e.g., divalent metal transporter (Dmt1) and ferroportin 1 (Fpn1)]. Iron deprivation also alters copper homeostasis, reflected by copper accumulation in the intestinal epithelium and induction of an intracellular copper-binding protein [metallothionein (Mt)] and a copper exporter [Menkes copper ATPase (Atp7a)]. Importantly, Atp7a is also a Hif2α target. It was, however, previously noted t

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Middleton, Maureen, Manuel Olivares, Alejandra Espinoza, Miguel Arredondo, Fernando Pizarro, and Carolina Valenzuela. "Exploratory Study: Excessive Iron Supplementation Reduces Zinc Content in Pork without Affecting Iron and Copper." Animals 11, no. 3 (2021): 776. http://dx.doi.org/10.3390/ani11030776.

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The aim of this work was to determine in an exploratory manner the effect of excessive iron supplementation on iron, zinc, and copper contents in pork and pork offal. Pigs averaging 50 days in age and 15 ± 1.3 kg body weight were allocated to a control group (500 ppm dietary Fe) and a supplemental group (3000 ppm dietary Fe). After an iron supplementation period of 60 days, blood samples were analyzed to determine iron biomarkers, serum copper, and zinc contents. Animals were slaughtered to assess total iron, non-heme iron, heme iron, zinc, and copper contents in samples of nine meat cuts and

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Saouli, Zoi, Zisis Kontoninas, Fotios Girtovitis, et al. "Copper and Iron Status in Myelodysplastic Syndromes." Blood 110, no. 11 (2007): 4593. http://dx.doi.org/10.1182/blood.v110.11.4593.4593.

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Abstract Introduction: Copper is an essential mineral found in many tissues. It is involved in iron incorporation into hemoglobin, hemolytic syndromes, while copper deficiency provokes iron overload and induces dysplastic changes to erythrocytes. On the other hand, there are references that iron overload can result in mild copper deficiency. There seems to be equivocal relationship between these two elements. Aim: The aim of this study is to determine copper and iron status in myelodysplastic patients and to investigate if copper deficiency correlates with the type of myelodysplastic syndrome.

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Zhang, Baojing, Tingan Zhang, and Zhihe Dou. "A Thermodynamic and Experimental Assessment of the Recovery of Copper, Iron, Zinc, and Lead from Copper Slag." Minerals 12, no. 5 (2022): 496. http://dx.doi.org/10.3390/min12050496.

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With the increases in the costs of iron and copper ores, the incongruity between the significant imports of these ores into China and the ongoing accumulation of unused copper slag has greatly increased. Even so, there are few low-value methods for the utilization of copper slag. The present work demonstrates the processing of this material via reduction whilst smelting wear-resistant cast iron. This system is able to recover copper, iron, zinc, and lead. The FactSage software package was used to calculate the reduction thermodynamics of the copper slag, and suitable conditions for the process

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Bremner, I., W. R. Humphries, M. Phillippo, M. J. Walker, and P. C. Morrice. "Iron-induced copper deficiency in calves: dose-response relationships and interactions with molybdenum and sulphur." Animal Science 45, no. 3 (1987): 403–14. http://dx.doi.org/10.1017/s0003356100002890.

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ABSTRACTThe effects of dietary supplements of iron, molybdenum and sulphur on copper metabolism in calves were examined. In one experiment, 27 castrated male pre-ruminant Friesian calves were given a milk-substitute ration containing 0·9, 4·5 or 9 mmol iron per kg dry matter for 8 weeks. The iron supplements had no effect on liver copper retention. When 24 of these calves were then given a diet based on barley grains and barley straw containing 0, 4·5, 9 or 13·5 mmols iron per kg for up to 24 weeks, liver and plasma copper concentrations were greatly reduced in all iron-supplemented animals bu

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Lestari, Ayu, and Irwan Said. "Analisis kadar mineral mikro tembaga dan besi pada biji durian." Media Eksakta 19, no. 1 (2023): 96–101. http://dx.doi.org/10.22487/me.v19i1.1112.

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This study aims to determine the levels of copper and iron contained in durian seeds, determine the levels of copper and iron using Atomic Absorption Spectrophotometer (AAS). The results showed that the analysis of the water content of durian seeds obtained 37.382%, ash content 17.782% and mass 44.835%. Analysis of the iron content measured at the copper wavelength of 248,3 nm, at the wavelength of 249,2, the results obtained respectively 49.244 ± 116.076 mg/100g for copper and 66.495± 15.753 mg/100g for iron. The results of this study are expected to be one of the alternative food ingredients

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Muñoz, Carlos, Ernesto Rios, Jorge Olivos, Oscar Brunser, and Manuel Olivares. "Iron, copper and immunocompetence." British Journal of Nutrition 98, S1 (2007): S24—S28. http://dx.doi.org/10.1017/s0007114507833046.

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Microminerals including copper and iron are essential to immunity and health in human beings. The development of powerful tools in analytical cell biology and molecular genetics has facilitated efforts to identify specific cellular and molecular functions of trace elements in the maturation, activation and functions of host defence mechanisms. Selected recent reports about the role of copper and iron nutrition on immune functions are critically analysed here. Effects of trace element supplementation on infectious morbidity are also reviewed. While micromineral deficiencies, in general, may hav

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Arredondo, Miguel, and Marco T. Núñez. "Iron and copper metabolism." Molecular Aspects of Medicine 26, no. 4-5 (2005): 313–27. http://dx.doi.org/10.1016/j.mam.2005.07.010.

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CRADDOCK, P. T., and N. D. MEEKS. "IRON IN ANCIENT COPPER." Archaeometry 29, no. 2 (1987): 187–204. http://dx.doi.org/10.1111/j.1475-4754.1987.tb00411.x.

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Hong, S. I. "Copper-Iron Filamentary Microcomposites." Advanced Engineering Materials 3, no. 7 (2001): 475–79. http://dx.doi.org/10.1002/1527-2648(200107)3:7<475::aid-adem475>3.0.co;2-c.

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Ravia, Jennifer J., Renu M. Stephen, Fayez K. Ghishan, and James F. Collins. "Menkes Copper ATPase (Atp7a) Is a Novel Metal-responsive Gene in Rat Duodenum, and Immunoreactive Protein Is Present on Brush-border and Basolateral Membrane Domains." Journal of Biological Chemistry 280, no. 43 (2005): 36221–27. http://dx.doi.org/10.1074/jbc.m506727200.

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We previously noted strong induction of genes related to intestinal copper homeostasis (Menkes Copper ATPase (Atp7a) and metallothionein) in the duodenal epithelium of iron-deficient rats across several stages of postnatal development (Collins, J. F., Franck, C. A., Kowdley, K. V., and Ghishan, F. K. (2005) Am. J. Physiol., 288, G964–G971). We now report significant copper loading in the livers and intestines of iron-deficient rats. These findings are consistent with the hypothesis that there is increased intestinal copper transport during iron deficiency. We additionally found that hepatic At

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Silva, D. M. de, and S. D. Aust. "Ferritin and ceruloplasmin in oxidative damage: review and recent findings." Canadian Journal of Physiology and Pharmacology 71, no. 9 (1993): 715–20. http://dx.doi.org/10.1139/y93-107.

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The oxidation of biomolecules such as lipid, protein, and DNA is associated with a variety of toxicities and pathologies. In an all-encompassing definition these oxidative processes have been referred to as "oxidative stress." Although the direct reaction between molecular oxygen and most biomolecules is spin forbidden, this reaction can be efficiently catalyzed by transition metals such as iron and copper. Iron especially has been demonstrated to be a potent catalyst of biological oxidations. This review focuses on the relationship between iron and copper with respect to the copper protein ce

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Hedrich, Sabrina, Chris du Plessis, Nelson Mora, and D. Barrie Johnson. "Reduction and Complexation of Copper in a Novel Bioreduction System Developed to Recover Base Metals from Mine Process Waters." Advanced Materials Research 825 (October 2013): 483–86. http://dx.doi.org/10.4028/www.scientific.net/amr.825.483.

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An integrated bio-processing scheme was devised and tested in the laboratory for recovering copper, or other base metals, from pregnant leach solutions (PLS) using a two-step process involving both iron-reduction, and sulfate-reduction for H2S generation and sulfide precipitation, as a potential alternative to conventional SX-EW. Reduction of ferric iron in the PLS was achieved using iron-reducingAcidithiobacillusspp. andSulfobacillus thermosulfidooxidansin column reactors containing elemental sulfur as electron donor. Analysis of the column reactor effluents showed not only that most of the f

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Rodriguez-Matas, M. C., F. Lisbona, A. E. Gómez-Ayala, I. López-Aliaga, and M. S. Campos. "Influence of nutritional iron deficiency development on some aspects of iron, copper and zinc metabolism." Laboratory Animals 32, no. 3 (1998): 298–306. http://dx.doi.org/10.1258/002367798780559248.

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This paper examines the development of iron (Fe) deficiency and its possible interactions with trace elements such as zinc (Zn) and copper (Cu) by investigating iron-deficient and control rats. The effects of iron deficiency were studied at day 0, 10, 20, 30 and 40 in rats fed on an iron-free diet (diet ID). It was found that the critical period in the development of nutritional iron deficiency occurs after 30 to 40 days without iron supplementation. At this time the organism is unable to maintain haemoglobin levels without endangering the iron-dependent enzymatic groups which are essential fo

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Tang, Qing Jie, Shao Fan, and Bo Liu. "Effect of the Additives on the Catalytic Performance of Iron-Ruthenium Composite Catalyst." Advanced Materials Research 160-162 (November 2010): 671–75. http://dx.doi.org/10.4028/www.scientific.net/amr.160-162.671.

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A series of Iron-Ruthenium composite catalyst were prepared by precipitation and immersion, the effect of potassium and copper were studied by the slurry bed reactor at 260°C、2MPa、CO／H2＝1∶1，and the reduction behavior of Iron-Ruthenium composite catalyst was studied by TPR. The experimental results showed that the performance of Iron-Ruthenium composite catalyst was better than single Iron-based catalyst. The addition of potassium and copper caused the catalytic performance of Iron-Ruthenium composite catalyst improve significantly, and Copper could improve significantly reduction effect on Iro

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Estienne, Mark, Kimberly Williams, Nima Emami, Sherri Clark-Deener, and Rami Dalloul. "Effects of different parenteral iron treatment regimens on hematology characteristics, serum concentrations of hepcidin, and growth performance in pigs fed nursery diets supplemented with copper." Journal of Swine Health and Production 30, no. 4 (2022): 210–22. http://dx.doi.org/10.54846/jshap/1288.

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Objective: To determine the effects of iron treatments on hematology, hepcidin, and growth in weaned pigs fed copper-supplemented diets. Materials and methods: Pigs were allocated to a 3 × 2 factorial arrangement of treatments (4 pens/treatment combination, 3 pigs/pen) with factors being intramuscular iron (200 mg at birth; 100 mg at birth and weaning [22.4 days of age]; or 100 mg at birth and 14 days of age) and dietary copper (14 [control] or 250 ppm [supplemented]). Blood was sampled at days 0, 7, and 49 post weaning. Results: Pigs receiving 100 mg iron at birth and weaning, but not pigs in

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Dubbels, Bradley L., Alan A. DiSpirito, John D. Morton, Jeremy D. Semrau, J. N. E. Neto, and Dennis A. Bazylinski. "Evidence for a copper-dependent iron transport system in the marine, magnetotactic bacterium strain MV-1." Microbiology 150, no. 9 (2004): 2931–45. http://dx.doi.org/10.1099/mic.0.27233-0.

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Cells of the magnetotactic marine vibrio, strain MV-1, produce magnetite-containing magnetosomes when grown anaerobically or microaerobically. Stable, spontaneous, non-magnetotactic mutants were regularly observed when cells of MV-1 were cultured on solid media incubated under anaerobic or microaerobic conditions. Randomly amplified polymorphic DNA analysis showed that these mutants are not all genetically identical. Cellular iron content of one non-magnetotactic mutant strain, designated MV-1nm1, grown anaerobically, was ∼20- to 80-fold less than the iron content of wild-type (wt) MV-1 for th

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Yamashita, S., A. Abe, and A. Noma. "Sensitive, Direct Procedures for Simultaneous Determinations of Iron and Copper in Serum, with Use of 2-(5-Nitro-2-Pyridylazo)-5-(N-Propyl-N-Sulfopropylamino)Phenol (Nitro-PAPS) as Ligand." Clinical Chemistry 38, no. 7 (1992): 1373–75. http://dx.doi.org/10.1093/clinchem/38.7.1373.

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Abstract We developed a direct, simple, and sensitive procedure for the simultaneous colorimetric assay of iron and copper in serum, using sodium dodecyl sulfate-ascorbic acid to dissociate iron and copper from transferrin and ceruloplasmin, respectively. We also use a new water-soluble reagent, 2-(5-nitro-2-pyridylazo)-5-(N-propyl-N-sulfopropylamino)phenol disodium salt (nitro-PAPS) and thioglycolic acid to eliminate interference from copper in the measurement of iron. Within- and between-run precisions of the present method were 2.5-2.8% for iron and 1.8-4.6% for copper. The proposed method

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Tang, Qing Jie, Wen Rong Wu, Xiao Min Yang, and Na Zhao. "Effect of Copper on Iron-Ruthenium Complex Catalyst for CO Hydrogenation." Advanced Materials Research 531 (June 2012): 276–79. http://dx.doi.org/10.4028/www.scientific.net/amr.531.276.

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A series of Iron-Ruthenium complex catalyst were prepared by precipitation and immersion. The effect of Copper was studied on Iron-Ruthenium complex catalyst for CO hydrogenation and temperature programmed reduction. The results show that the effect of Copper is important to Iron-Ruthenium complex catalyst for CO hydrogenation. The selectivity of Olefin improved obviously with copper adding into Iron-Ruthenium complex catalyst, and the intensity of reducing peak increased significantly

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