Academic literature on the topic 'Corneal transplantation'

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Journal articles on the topic "Corneal transplantation"

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Nakagawa, Hayate, Tomas Blanco, Francesca Kahale, Rohan Bir Singh, Thomas H. Dohlman, and Reza Dana. "Novel adaptation of a running suture technique in a mouse model of corneal transplantation." Journal of Biological Methods 8, no. 4 (2021): 1. http://dx.doi.org/10.14440/jbm.2021.373.

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Several murine models of corneal transplantation have been developed over the years to study the immunopathological processes that lead to the failure of grafted corneas. In all of them, the classic eight interrupted sutures technique is utilized for transplanting the donor cornea on the host bed. However, in clinical practice, a single continuous suture with a single knot is generally performed for corneal transplantation. Here, we describe the adaptation of the single continuous suture technique in a mouse model of corneal transplantation.
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Salabarria, Ann-Charlott, Manuel Koch, Alfrun Schönberg, et al. "Topical VEGF-C/D Inhibition Prevents Lymphatic Vessel Ingrowth into Cornea but Does Not Improve Corneal Graft Survival." Journal of Clinical Medicine 9, no. 5 (2020): 1270. http://dx.doi.org/10.3390/jcm9051270.

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Vascular endothelial growth factor-C/D (VEGF-C/D) regulates lymphangiogenesis. Ingrowth of lymphatic vessels is negatively associated with corneal transplantation success. In this study, we therefore analyzed the effect local blockade of VEGF-C/D has on inflamed corneas. We used the murine model of suture-induced neovascularization and subsequent high-risk corneal transplantation. Mice were treated with a VEGF-C/D trap prior to transplantation. Topical inhibition of VEGF-C/D significantly reduced lymphatic vessel ingrowth, but increased Macrophage numbers in the cornea. Furthermore, corneal tr
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Procházková, Alexandra, Martina Poláchová, Jakub Dítě, Magdaléna Netuková, and Pavel Studený. "Chemical, Physical, and Biological Corneal Decellularization Methods: A Review of Literature." Journal of Ophthalmology 2024 (March 25, 2024): 1–17. http://dx.doi.org/10.1155/2024/1191462.

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The cornea is one of the most commonly transplanted tissues worldwide. It is used to restore vision when severe visual impairment or blindness occurs in patients with corneal diseases or after trauma. Due to the global shortage of healthy donor corneas, decellularized corneal tissue has significant potential as an alternative to corneal transplantation. It preserves the native and biological ultrastructure of the cornea and, therefore, represents the most promising scaffold. This article discusses different methods of corneal decellularization based on the current literature. We searched PubMe
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Sakowska, Justyna, Paulina Glasner, Maciej Zieliński, Piotr Trzonkowski, and Leopold Glasner. "Corneal Allografts: Factors for and against Acceptance." Journal of Immunology Research 2021 (October 3, 2021): 1–11. http://dx.doi.org/10.1155/2021/5372090.

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Cornea is one of the most commonly transplanted tissues worldwide. However, it is usually omitted in the field of transplantology. Transplantation of the cornea is performed to treat many ocular diseases. It restores eyesight significantly improving the quality of life. Advancements in banking of explanted corneas and progressive surgical techniques increased availability and outcomes of transplantation. Despite the vast growth in the field of transplantation laboratory testing, standards for corneal transplantation still do not include HLA typing or alloantibody detection. This standard pract
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Ostrovski, D. S., S. A. Borzenok, B. E. Malyugin, O. P. Antonova, M. Kh Khubetsova та T. Z. Kerimov. "Проблема получения клеточной культуры эндотелиальных клеток роговицы для регенеративных целей". Russian Journal of Transplantology and Artificial Organs 26, № 2 (2024): 135–44. http://dx.doi.org/10.15825/1995-1191-2024-2-135-144.

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Human posterior corneal epithelium (corneal endothelium) has limited proliferative activity both in vivo and in vitro. Disease or dysfunction in these cells leads to impaired corneal transparency of varying degrees of severity, up to blindness. Currently, the only effective standard treatment for corneal endothelial dysfunction is transplantation of donor cornea that contains a pool of healthy and functionally active cells. However, there is a global shortage of donor corneas, which has led to an unmet clinical need and the fact that only 1 patient out of 10 in need receives surgical treatment
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Cen, Yu-Jie, Wei Wang, and Yun Feng. "Preliminary studies of constructing a tissue-engineered lamellar corneal graft by culturing mesenchymal stem cells onto decellularized corneal matrix." International Journal of Ophthalmology 14, no. 1 (2021): 10–18. http://dx.doi.org/10.18240/ijo.2021.01.02.

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AIM: To construct a competent corneal lamellar substitute in order to alleviate the shortage of human corneal donor. METHODS: Rabbit mesenchymal stem cells (MSCs) were isolated from bone marrow and identified by flow cytometric, osteogenic and adipogenic induction. Xenogenic decellularized corneal matrix (XDCM) was generated from dog corneas. MSCs were seeded and cultured on XDCM to construct the tissue-engineered cornea. Post-transplantation biocompatibility of engineered corneal graft were tested by animal experiment. Rabbits were divided into two groups then underwent lamellar keratoplasty
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Guérin, Louis-Philippe, Gaëtan Le-Bel, Pascale Desjardins, et al. "The Human Tissue-Engineered Cornea (hTEC): Recent Progress." International Journal of Molecular Sciences 22, no. 3 (2021): 1291. http://dx.doi.org/10.3390/ijms22031291.

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Each day, about 2000 U.S. workers have a job-related eye injury requiring medical treatment. Corneal diseases are the fifth cause of blindness worldwide. Most of these diseases can be cured using one form or another of corneal transplantation, which is the most successful transplantation in humans. In 2012, it was estimated that 12.7 million people were waiting for a corneal transplantation worldwide. Unfortunately, only 1 in 70 patients received a corneal graft that same year. In order to provide alternatives to the shortage of graftable corneas, considerable progress has been achieved in the
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Brunette, Isabelle, Emilio I. Alarcon, and May Griffith. "Cornea Regeneration as an Alternative to Human Donor Transplantation." European Ophthalmic Review 09, no. 02 (2015): 111. http://dx.doi.org/10.17925/eor.2015.09.02.111.

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There is a need for an alternative to human donor corneas as the availability of good-quality tissues remains limited, with this situation potentially worsening as the population in many countries is progressively ageing. There have been numerous attempts to develop corneal equivalent as alternatives to donated human corneas as well as prostheses. In this short review, we focus on the efforts in bioengineering implants that promote regeneration by Canadian researchers, including our current team of authors. The examples of technologies developed that we describe include biomaterials that allow
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McTiernan, Christopher D., Fiona C. Simpson, Michel Haagdorens, et al. "LiQD Cornea: Pro-regeneration collagen mimetics as patches and alternatives to corneal transplantation." Science Advances 6, no. 25 (2020): eaba2187. http://dx.doi.org/10.1126/sciadv.aba2187.

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Transplantation with donor corneas is the mainstay for treating corneal blindness, but a severe worldwide shortage necessitates the development of other treatment options. Corneal perforation from infection or inflammation is sealed with cyanoacrylate glue. However, the resulting cytotoxicity requires transplantation. LiQD Cornea is an alternative to conventional corneal transplantation and sealants. It is a cell-free, liquid hydrogel matrix for corneal regeneration, comprising short collagen-like peptides conjugated with polyethylene glycol and mixed with fibrinogen to promote adhesion within
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Wan, Lu-Qin, Hui-Feng Wang, Chen Chen, et al. "Efficacy of rhNGF-loaded amniotic membrane transplantation for rabbit corneal epithelial and nerve regeneration." International Journal of Ophthalmology 14, no. 11 (2021): 1653–59. http://dx.doi.org/10.18240/ijo.2021.11.02.

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AIM: To evaluate the efficacy of recombinant human nerve growth factor-loaded amniotic membrane (rhNGF-AM) on corneal epithelial and nerve regeneration in rabbit model. METHODS: Freshly prepared human amniotic membrane (AM) were immersed into PBS buffer containing 100 or 500 μg/mL rhNGF for 15, 30, and 60min at 4℃. The in vitro release kinetics of rhNGF was measured with ELISA. For in vivo evaluation, the AM were immersed with 500 μg/mL rhNGF for 30min. Fifty-seven rabbits were selected to establish corneal epithelial defect model. In addition to the 19 rabbits in control group, 38 rabbits rec
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Dissertations / Theses on the topic "Corneal transplantation"

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Parekh, Mohit. "Human corneal endothelial cell culture and corneal transplantation." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3422398.

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Cornea is the front transparent window of the eye which is responsible for optimal and clear vision. Transparency of this tissue is highly inevitable and cannot be compromised. Human cornea is made up of multiple layers out of which the posterior layer ‘endothelium’ is responsible for the transparency of the cornea. Endothelium is a monolayer of cells that allow the ions and solutes to transport from aqueous humour to the cornea and back which in turn maintains the transparency of the cornea by preserving the homeostasis between the anterior and posterior cornea. Earlier, it was observed that
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Brice, Sarah Louise, and sarahlbrice@gmail com. "Regional Immunosuppression for Corneal Transplantation." Flinders University. Medicine, 2010. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20100811.113448.

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Corneal transplantation is performed to restore vision or to relieve pain in patients with damaged or diseased corneas. However, approximately 40% of corneal allografts fail after 10 years. The most common cause of graft failure is irreversible immunological rejection, primarily mediated by CD4+ T cells, despite the topical application of glucocorticosteroids. The aim of this project was to investigate the anatomic site of antigen presentation during corneal transplantation in the rat, by using a lentiviral vector to express an anti-CD4 antibody fragment at potential sites of antigen presentat
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Arancibia, Carcamo Carolina Virgina. "Class II MHC on corneal endothelium : implications for corneal transplantation." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395028.

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Elzawia, Omar Rajab. "Corneal graft outcome, endothelial monolayer survival following corneal grafting : a prospective and retrospective study." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322567.

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Torres, Paulo Francisco de Ancede Aires de Sousa. "The Role of cytokines during corneal transplantation : Studies on immunopathological mechanisms of corneal rejection." Doctoral thesis, Universidade do Porto. Reitoria, 1999. http://hdl.handle.net/10216/10584.

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Torres, Paulo Francisco de Ancede Aires de Sousa. "The Role of cytokines during corneal transplantation : Studies on immunopathological mechanisms of corneal rejection." Tese, Universidade do Porto. Reitoria, 1999. http://hdl.handle.net/10216/10584.

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Tsang, K. "Prioritization preferences for corneal transplantation allocation in Hong Kong." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31972226.

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Rayner, Sandra Anne. "Tumour necrosis factor and gene transfer in corneal transplantation." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248143.

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Winton, Helen Louise. "Inflammation related genetic variants in high risk corneal transplantation." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617796.

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Corneal transplantation is the oldest, most common and usually the most successful type of solid tissue allograft. The acceptancc of corneal allografts compared to other categories of allografts is called immune privilege. However, some conditions rob the corneal allograft of its immune privilege and promote rejection, which remains the leading cause of corneal graft failure. The precise immune mechanism underlying graft failure is incompletely understood. While differences in human leukocyte antigen (HLA) molecules between donor and host contribute to the alloreactivity driving the donor-anti
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Tsang, K., and 曾光. "Prioritization preferences for corneal transplantation allocation in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31972226.

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Books on the topic "Corneal transplantation"

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Jacob, Soosan. Corneal Transplantation. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-5596-8.

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Hjortdal, Jesper, ed. Corneal Transplantation. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-24052-7.

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Mannis, Mark J. Corneal transplantation: A history in profiles. J.P. Wayenborgh, 1999.

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Thomas, John. Corneal endothelial transplant: (DSAEK, DMEK & DLEK). Jaypee-Highlights Medical Pub., 2010.

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MD, John Thomas, ed. Lamellar corneal surgery. Jaypee Brothers Medical Publishers, 2008.

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A, Mannis Avi, and Albert Daniel M, eds. Corneal transplantation: A history in profiles. J.P. Wayenborgh, 1999.

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1951-, Price Francis W., and Price Marianne O. 1952-, eds. DSEK: What you need to know about endothelial keratoplasty. SLACK Inc., 2009.

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N, Westerhouse Alan, ed. Eye research developments: Glaucoma, corneal transplantation, and bacterial eye infections. Nova Science Publishers, 2009.

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N, Westerhouse Alan, ed. Eye research developments: Glaucoma, corneal transplantation, and bacterial eye infections. Nova Science Publishers, 2009.

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Hill, John Clifford. The mechanism and management of corneal graft rejection. Kugler, 1996.

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Book chapters on the topic "Corneal transplantation"

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Zuberbuhler, Bruno, Stephen Tuft, David Gartry, and David Spokes. "Corneal Transplantation." In Corneal Surgery. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-12502-7_3.

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Williams, Keryn A. "Corneal transplantation." In Yearbook of Cell and Tissue Transplantation 1996–1997. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0165-0_9.

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van Rij, Gabriël, and Bart T. H. van Dooren. "The History of Corneal Transplantation." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_1.

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Armitage, W. John, and Margareta Claesson. "National Corneal Transplant Registries." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_10.

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Brunette, Isabelle, Catherine Beauchemin, and Jean Lachaine. "Economic Evaluation of Keratoplasty." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_11.

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Krootila, Kari, Olli Wetterstrand, and Juha Holopainen. "Post-keratoplasty Astigmatism." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_12.

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De Sanctis, Ugo. "Optics of Transplanted Grafts: IOL Calculation in Grafted Patients." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_13.

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Albé, Elena, and Massimo Busin. "Mechanical Microkeratomes." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_14.

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Williams, Geraint P., and Jodhbir S. Mehta. "Technology: Femtosecond Laser in Keratoplasty." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_15.

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Rama, Paolo, Stanislav Matuska, and Graziella Pellegrini. "Limbal Stem-Cell Expansion and Transplantation." In Corneal Transplantation. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24052-7_16.

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Conference papers on the topic "Corneal transplantation"

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Antony, Maria Merin, and Murukeshan Vadakke Matham. "Corneal quality assessment for corneal transplantation using hyperspectral imaging." In JSAP-Optica Joint Symposia. Optica Publishing Group, 2024. https://doi.org/10.1364/jsapo.2024.17a_a37_2.

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Cornea is the most widely transplanted human tissue. To ensure good surgical results and effective visual recovery, thorough screening of donors and donor tissues is necessary throughout the process [1]. This screening minimizes the risk of transmitting infectious diseases and environmental contaminants to the recipient, while also guaranteeing the transplant’s high optical and functional quality. Therefore, the quality assessment of the cornea at various stages - from donor selection to the transplantation procedure is crucial to ensure its longevity and effectiveness.
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Díez-Ajenjo, M. Amparo, M. Carmen García Domene, M. Josefa Luque Cobija, Mariola Penadés Fons, Diana Martínez Martínez, and Eduardo García Martínez. "THEORETICAL-PRACTICAL SEMINAR ON CORNEAL TRANSPLANTATION FOR OPTOMETRY STUDENTS." In 13th International Technology, Education and Development Conference. IATED, 2019. http://dx.doi.org/10.21125/inted.2019.0671.

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Menabuoni, Luca, B. Dragoni, and Roberto Pini. "Preliminary experiences on diode laser welding in corneal transplantation." In BiOS Europe '96, edited by Gregory B. Altshuler, Fausto Chiesa, Herbert J. Geschwind, et al. SPIE, 1996. http://dx.doi.org/10.1117/12.260709.

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Okumura, Naoki. "P47-A153 Transplantation of cultured human corneal endothelial cells." In Abstracts from the 2023 Annual Meeting of the European Eye Bank Association (Aachen, Germany - 2-4 March 2023). BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjophth-2023-eeba.46.

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Lagali, Neil S. "Need for technologies in advanced corneal research, diagnosis, and transplantation." In Ophthalmic Technologies XXIX, edited by Fabrice Manns, Per G. Söderberg, and Arthur Ho. SPIE, 2019. http://dx.doi.org/10.1117/12.2520656.

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Tinena, F., P. Sobrevilla, and E. Montseny. "On quality assessment of corneal endothelium and its possibility to be used for surgical corneal transplantation." In 2009 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE). IEEE, 2009. http://dx.doi.org/10.1109/fuzzy.2009.5277395.

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Bostan, Caremans, Huizing, Leandro Ferreira, Vlyminck, and Vermeulen. "24 Is there an impact of cancer treatment on corneal transplantation?" In EEBA 2024 abstracts. BMJ Publishing Group Ltd, 2024. https://doi.org/10.1136/bmjophth-2024-eeba.24.

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Paulus, Ulrike, Ines Ushiro-Lumb, Cathy Hopkinson, Lewis Downward, and Shaminie Shanmugaranjan. "6 The impact of COVID-19 on corneal transplantation in England." In Abstracts of the European Eye Bank Association Virtual Meeting, 3–5 March 2022. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/bmjophth-2022-eeba.6.

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Dong, Hua, and Xueying Yang. "The project management of corneal transplantation in animal experiments based on BP neural network." In 2017 IEEE 6th Data Driven Control and Learning Systems Conference (DDCLS). IEEE, 2017. http://dx.doi.org/10.1109/ddcls.2017.8068121.

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Tsui, Rachel, Vanissa Chow, Catherine Wong, et al. "P29-A135 Impact of COVID-19 on corneal donation and transplantation in Hong Kong." In Abstracts from the 2023 Annual Meeting of the European Eye Bank Association (Aachen, Germany - 2-4 March 2023). BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/bmjophth-2023-eeba.28.

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